Sina Farsiu | Scholars@Duke

Sina Farsiu
Associate Professor in the Department of Biomedical Engineering

I am the director of the Vision and Image Processing (VIP) Laboratory. Along with my colleagues, we investigate how to improve early diagnostic methods and find new imaging biomarkers of ocular and neurological diseases in adults (e.g. age-related macular degeneration, diabetic retinopathy, Glaucoma, Alzheimer) and children (e.g. retinopathy or prematurity). We also develop automatic segmentation algorithms to detect/segment/quantify anatomical/pathological structures seen on medical images.

On another front, we study efficient signal processing based methods to overcome the theoretical and practical limitations that constrain the achievable resolution of any imaging device. Our approach, which is based on adaptive extraction and robust fusion of relevant information from the expensive and sophisticated as well as simple and cheap sensors, has found wide applications in improving the quality of imaging systems such as ophthalmic SD-OCT, digital X-ray mammography, electronic and optical microscopes, and commercial digital camcorders. We are also interested in pursuing statistical signal processing based projects, including super-resolution, demosaicing, deblurring, denoising, motion estimation, compressive sensing/adaptive sampling, and sensor fusion.

Current Appointments & Affiliations

Associate Professor in the Department of Biomedical Engineering, Biomedical Engineering, Pratt School of Engineering 2016
Associate Professor in the Department of Ophthalmology, Ophthalmology, Clinical Science Departments 2016
Associate Professor in the Department of Electrical and Computer Engineering, Electrical and Computer Engineering, Pratt School of Engineering 2018
Faculty Network Member of the Duke Institute for Brain Sciences, Duke Institute for Brain Sciences, University Institutes and Centers 2012

Contact Information

Box 3802 Med Ctr, Durham, NC 27710
CIEMAS 2575, Durham, NC 27708
(919) 684-6642
Academic Webpage
Google Scholar
Vision & Image Processing Lab

Background
Education, Training, & Certifications
- Postdoctoral Scholar, Electrical Engineering, University of California at Los Angeles 2006 - 2007
- Research Assistant, Electrical Engineering, University of California at Los Angeles 2001 - 2005
Duke Appointment History
- Assistant Professor in the Department of Electrical and Computer Engineering, Electrical and Computer Engineering, Pratt School of Engineering 2013 - 2017
- Assistant Professor in the Department of Computer Science, Computer Science, Trinity College of Arts & Sciences 2013 - 2017
- Assistant Professor in the Department of Ophthalmology, Ophthalmology, Clinical Science Departments 2014 - 2016
- Assistant Professor in the Department of Biomedical Engineering, Biomedical Engineering, Pratt School of Engineering 2014 - 2016
- Assistant Professor of Ophthalmology, Ophthalmology, Clinical Science Departments 2013 - 2014
- Assistant Professor - Track V of Ophthalmology, Ophthalmology, Clinical Science Departments 2009 - 2013
- Assistant Research Professor of Biomedical Engineering, Biomedical Engineering, Pratt School of Engineering 2009 - 2011
Recognition
In the News
- SEP 20, 2017
  
  Farsiu Receives Signal Processing Award
- JAN 19, 2017 Pratt School of Engineering
  
  Farsiu Wins ARVO Foundation/Pfizer Ophthalmics Carl Camras Translational Research Award
- AUG 10, 2016 WUNC
  
  New handheld device could allow for easy retina imaging in children
- MAR 4, 2016 The News & Observer
  
  At Duke, sibling sleuths try to unlock mummy mystery
- APR 29, 2015 The Daily Mail, Australian Associated Press
  
  Eye test could detect dementia
- AUG 29, 2014
  
  Sina Farsiu: Biomedical Engineer Processes an Avalanche of Images
- FEB 10, 2014 Duke Research Blog
  
  Duke Labs Produce 2 Intel Talent Search Finalists
Expertise
Subject Headings
Research
Selected Grants
- Advanced a/LCI systems for improved clinical utility awarded by National Institutes of Health 2016 - 2021
- Psychophysics-Guided Signal Processing for Retinal Prosthetics awarded by National Institutes of Health 2018 - 2020
- Analyzing retinal microanatomy in retinopathy of prematurity to improve care awarded by National Institutes of Health 2016 - 2020
- Whole Eye Optical Coherence Tomography to Improve Refractive Surgery and Eye Care awarded by National Institutes of Health 2014 - 2019
- NCS-FO:Real-time optical readout and control of population neural activity with cellular resolution awarded by National Science Foundation 2015 - 2019
- Training in Medical Imaging awarded by National Institutes of Health 2003 - 2019
- RPB: 2014 Nelson Trust Award awarded by Research To Prevent Blindness, Inc. 2014 - 2019
- Automated Software for Analysis of Adaptive Optics Scanning Laser Ophthalmoscopy Images awarded by Foundation Fighting Blindness, Inc 2016 - 2019
- Coherent light scattering for early detection of Alzheimer's disease awarded by National Institutes of Health 2017 - 2019
- Flavoprotein Autofluorescence Imaging in AMD awarded by National Institutes of Health 2015 - 2018
- Handheld Portable Adaptive Optics Scanning Laser Ophthalmoscope for Imaging Young Children awarded by National Institutes of Health 2016 - 2018
- Computer Aided Classification of Diabetic Macular Edema awarded by National Institutes of Health 2012 - 2018
- Temporal dynamics of retinal ganglion cell neurodegeneration in glaucoma awarded by National Institutes of Health 2015 - 2018
- Intraoperative OCT Guidance of Intraocular Surgery awarded by National Institutes of Health 2013 - 2017
- OCT measurement of TM/SC stiffness in living mice awarded by BrightFocus Foundation 2015 - 2017
- Smartphone Ophthalmoscope Lens Vascularity awarded by Research Triangle Institute International 2015 - 2017
- UPenn - NEI Follow-up Study: Comparison of AMD Treatment Trials (CATT) YR3 awarded by University of Pennsylvania 2013 - 2017
- Knight's Template OCT in Normal Children awarded by Knights Templar Eye Foundation, Inc. 2015 - 2017
- Field Deployable Optical Coherence Tomography for Triage of Ocular Trauma awarded by United States Army Medical Research and Materiel Command 2012 - 2016
- Smartphone ophthalmoscope image analysis of lens capsule vascularity to estimate preterm gestational age awarded by Research Triangle Institute 2014 - 2016
- Novel Retinal Biomarkers for Early Detection of Alzheimer's Disease awarded by Alzheimer's Association 2013 - 2016
- Coherent light scattering for early detection of retinal disease awarded by National Institutes of Health 2013 - 2016
- Coordinating Center for the Comparison of AMD Treatments Trials awarded by University of Pennsylvania 2014 - 2015
- Portable Motion Compensated SDOCT System for Imaging Young Children awarded by National Institutes of Health 2012 - 2014
- Real Time Intraoperative SDOCT for Vitreoretinal Surgery awarded by National Institutes of Health 2009 - 2012
Publications & Artistic Works
Selected Publications
- Book Sections
  - Li, XT, Chiu, SJ, Nicholas, P, Toth, CA, Izatt, JA, and Farsiu, S. "Segmentation of ophthalmic Optical Coherence Tomography images using graph cuts." 2010. Full Text
  - Toth, CA, Farsiu, S, Khanifar, A, and Chong, G. "Applications of spectral-domain OCT in AMD." In Optical Coherence Tomography in Age-Related Macular Degeneration: OCT in AMD, 15-34. December 1, 2009. Full Text
  - Farsiu, S, Chiu, SJ, Izatt, JA, and Toth, CA. "Fast detection and segmentation of drusen in retinal optical coherence tomography images." 2008. Full Text
  - Robinson, MD, Farsiu, S, Lo, JY, and Toth, CA. "Efficient restoration and enhancement of super-resolved X-ray images." 629-632. 2008. Full Text
- Conference Papers
  - Sleiman, K, Veerappan, M, Winter, KP, McCall, MN, Yiu, G, Farsiu, S, Chew, EY, Clemons, T, Toth, CA, and Age-Related Eye Disease Study 2 Ancillary Spectral Domain Optical Coherence Tomography Study Group, . "Optical Coherence Tomography Predictors of Risk for Progression to Non-Neovascular Atrophic Age-Related Macular Degeneration." December 2017. Full Text
  - LaRocca, F, DuBose, TB, Farsiu, S, and Izatt, JA. "Optical photon reassignment super-resolved scanning laser ophthalmoscopy." 2017. Full Text Link to Item
  - Allingham, MJ, Mukherjee, D, Lally, E, Rabbani, H, Mettu, PS, Cousins, SW, and Farsiu, S. "A quantitative approach to predict differential effects of anti-VEGF treatment on diffuse and focal leakage in patients with diabetic macular edema." September 2016. Link to Item
  - Ashpole, NE, Mukherjee, D, Li, G, Maccarini, P, Sherwood, JM, Ethier, CR, Overby, DR, Farsiu, S, and Stamer, WD. "IOP-induced Changes in Schlemm's Canal Dimensions and the Relation to Shear Stress." September 2016. Link to Item
  - Cunefare, D, Cooper, RF, Higgins, BP, Dubra, A, Carroll, J, and Farsiu, S. "Automated Detection of Cone Photoreceptors in Split Detector Adaptive Optics Scanning Light Ophthalmoscope Images." September 2016. Link to Item
  - Davila, J, Bavinger, C, Dunbar, GE, Stem, M, Kwark, L, Farsiu, S, and Gardner, TW. "Effects of panretinal photocoagulation on macular structure and function in patients with proliferative diabetic retinopathy." September 2016. Link to Item
  - DuBose, TB, Milanfar, P, Izatt, JA, and Farsiu, S. "Fundamental Bounds on Accuracy of Human Retinal SDOCT Image Segmentation based on Retinal Layer-Specific Noise Models." September 2016. Link to Item
  - LaRocca, F, Nankivil, D, Dubose, T, Toth, CA, Farsiu, S, and Izatt, JA. "Parafoveal cone photoreceptor imaging in infants and young children using an ultra-compact SLO/OCT handheld probe." September 2016. Link to Item
  - Lad, EM, Mukherjee, D, Vann, RR, Clemons, TE, Chew, EY, Jaffe, GJ, and Farsiu, S. "Novel software to assess correlation between MAIA microperimetry and OCT imaging of ellipsoid zone in type 2 idiopathic macular telangiectasia." September 2016. Link to Item
  - Li, G, Mukherjee, D, Navarro, I, Farsiu, S, Gonzalez, P, Kopczynski, C, and Stamer, WD. "Real-time Visualization of AR-13324 Effects on Schlemm's Canal and Scleral Vessels in Living Mice." September 2016. Link to Item
  - Mukherjee, D, Li, G, Stamer, WD, and Farsiu, S. "Segmentation and analysis software for mapping aqueous humor outflow pattern in living mice." September 2016. Link to Item
  - Polans, J, LaRocca, F, Carrasco-Zevallos, O, Keller, B, Lad, EM, Whitson, H, Kuo, AN, Farsiu, S, and Izatt, JA. "Wide-Field Sensorless Adaptive Optics Optical Coherence Tomography for Enhanced Visualization of the Retinal Periphery." September 2016. Link to Item
  - Vuong, V, Moisselev, E, Cunefare, D, Farsiu, S, Moshiri, A, and Yiu, G. "Repeatability of choroidal thickness measurements on Enhanced Depth Imaging OCT using different posterior boundaries." September 2016. Link to Item
  - Walter, S, Grewal, DS, Cunefare, D, Bhullar, PK, Farsiu, S, and Mahmoud, TH. "Topography of the Vitreoretinal Interface in Vitreomacular Traction Syndrome." September 2016. Link to Item
  - Whitson, H, Farsiu, S, Stinnett, SS, Kwark, L, Potter, G, Burke, J, Cousins, SW, and Lad, EM. "Retinal Biomarkers of Alzheimer's Disease." September 2016. Link to Item
  - DuBose, TB, Milanfar, P, Izatt, JA, and Farsiu, S. "Optical coherence tomography noise modeling and fundamental bounds on human retinal layer segmentation accuracy." 2016. Full Text Link to Item
  - Hu, F, Morhard, R, Liu, H, Murphy, H, Farsiu, S, and Ramanujam, N. "Label-free vascular imaging in a spontaneous hamster cheek pouch carcinogen model for pre-cancer detection (Conference Presentation)." 2016. Full Text Link to Item
  - Viehland, C, Keller, B, Carrasco-Zevallos, O, Cunefare, D, Shen, L, Toth, C, Farsiu, S, and Izatt, JA. "Novel real-time volumetric tool segmentation algorithm for intraoperative microscope integrated OCT (Conference Presentation)." 2016. Full Text Link to Item
  - Allingham, MJ, Izatt, D, Nie, Q, Lad, EM, Mettu, PS, Cousins, SW, and Farsiu, S. "Robust, easy-to-use, semiautomated software quantifies lesion rim area hyperautofluorescence and predicts progression of geographic atrophy." June 2015. Link to Item
  - Bozho-Todorich, , Shieh, C, DeSouza, P, Carrasco-Zevallos, O, Cunefare, D, Izatt, JA, Farsiu, S, Mruthyunjaya, P, Kuo, AN, and Toth, CA. "Impact of Microscope Integrated OCT on ophthalmology resident performance of anterior segment maneuvers in model eyes." June 2015. Link to Item
  - Chandramohan, A, Wright, JP, Fernandez, XD, Zhuang, J, Kwark, L, Farsiu, S, Cousins, SW, Madden, D, Lad, EM, and Whitson, HE. "Relationships between Retinal Nerve Fiber Layer and Brain Changes in Age-Related Macular Degeneration." June 2015. Link to Item
  - Gunther, RC, Toth, CA, Veerappan, M, Michelson, M, Tai, V, Winter, K, Folgar, FA, Chew, EY, and Farsiu, S. "Association of drusen substructure findings on SD-OCT with abnormal drusen volumes and progression to choroidal neovascularization in the AREDS2 Ancillary Study." June 2015. Link to Item
  - Lad, EM, Cousins, SW, Farsiu, S, and Proia, AD. "Retinal Macrophages in Stages of Age-related Macular Degeneration." June 2015. Link to Item
  - Rothman, A, Sevilla, MB, El-Dairi, M, Shimony, J, Gustafson, K, Pizoli, C, Tong, A, Farsiu, S, Freedman, S, and Toth, CA. "Very Preterm Neonatal Retinal Nerve Fiber Layer Thickness is a Biomarker of Brain Anatomy and Neurodevelopmental Health." June 2015. Link to Item
  - Sevilla, MB, Jr, MG, Lad, E, Clark, ME, Yuan, E, Farsiu, S, Curcio, CA, Owsley, C, and Toth, CA. "Relating retinal morphology on spectral domain optical coherence tomography (SDOCT) to macular function in aging and early to intermediate age-related macular degeneration (AMD)." June 2015. Link to Item
  - Simonett, J, Huang, R, Siddique, N, Farsiu, S, Siddique, T, Volpe, NJ, and Fawzi, AA. "Retinal Structural Changes in Amyotrophic Lateral Sclerosis (ALS)." June 2015. Link to Item
  - Whitson, HE, Farsiu, S, Stinnett, S, Lee, S, Kwark, L, Potter, G, Burke, J, Cousins, SW, and Lad, E. "Retinal imaging biomarkers for early diagnosis of Alzheimer's disease." June 2015. Link to Item
  - Yiu, G, Chiu, SJ, Petrou, PA, Stinnett, S, Sarin, N, Farsiu, S, Chew, EY, Wong, WT, and Toth, CA. "Relationship of Central Choroidal Thickness with Age-Related Macular Degeneration Status." June 2015. Link to Item
  - LaRocca, F, Nankivil, D, DuBose, T, Farsiu, S, and Izatt, JA. "Ultra-compact switchable SLO/OCT handheld probe design." 2015. Full Text Link to Item
  - McNabb, RP, LaRocca, F, Farsiu, S, Kuo, AN, and Izatt, JA. "Distributed scan SDOCT improves post refractive surgery corneal biometry." December 1, 2012.
  - Robinson, MD, Farsiu, S, Lo, JY, Toth, CA, and IEEE, . "Efficient Restoration and Enhancement of Super-resolved X-ray Images." 2008. Link to Item
  - Farsiu, S, Milanfar, P, and IEEE, . "Multi-scale statistical detection and ballistic imaging through turbid media." 2007. Link to Item
  - Farsiu, S, Elad, M, Milanfar, P, and IEEE, . "Constrained, globally optimal, multi-frame motion estimation." 2005. Full Text Link to Item
- Journal Articles
  - Gibson, A, Piquette, KE, Bergmann, U, Christens-Barry, W, Davis, G, Endrizzi, M, Fan, S, Farsiu, S, Fitzgerald, A, Griffiths, J, Jones, C, Li, G, Manning, PL, Maughan Jones, C, Mazza, R, Mills, D, Modregger, P, Munro, PRT, Olivo, A, Stevenson, A, Venugopal, B, Wallace, V, Wogelius, RA, Toth, MB, and Terras, M. "An assessment of multimodal imaging of subsurface text in mummy cartonnage using surrogate papyrus phantoms (Accepted)." Heritage Science 6, no. 1 (December 1, 2018). Full Text
  - Willoughby, AS, Vuong, VS, Cunefare, D, Farsiu, S, Noronha, G, Danis, RP, and Yiu, G. "Choroidal Changes After Suprachoroidal Injection of Triamcinolone in Eyes With Macular Edema Secondary to Retinal Vein Occlusion." American journal of ophthalmology (March 22, 2018). (Letter) Full Text
  - Soltanian-Zadeh, S, Gong, Y, and Farsiu, S. "Information-Theoretic Approach and Fundamental Limits of Resolving Two Closely-Timed Neuronal Spikes in Mouse Brain Calcium Imaging (Accepted)." IEEE Transactions on Biomedical Engineering (March 7, 2018). Full Text
  - Patel, TP, Prajna, NV, Farsiu, S, Valikodath, NG, Niziol, LM, Dudeja, L, Kim, KH, and Woodward, MA. "Novel Image-Based Analysis for Reduction of Clinician-Dependent Variability in Measurement of the Corneal Ulcer Size." Cornea 37, no. 3 (March 2018): 331-339. Full Text
  - Yiu, G, Wang, Z, Munevar, C, Tieu, E, Shibata, B, Wong, B, Cunefare, D, Farsiu, S, Roberts, J, and Thomasy, SM. "Comparison of chorioretinal layers in rhesus macaques using spectral-domain optical coherence tomography and high-resolution histological sections." Experimental eye research 168 (March 2018): 69-76. Full Text
  - Willoughby, AS, Vuong, VS, Cunefare, D, Farsiu, S, Noronha, G, Danis, RP, and Yiu, G. "Choroidal Changes After Suprachoroidal Injection of Triamcinolone Acetonide in Eyes With Macular Edema Secondary to Retinal Vein Occlusion." American journal of ophthalmology 186 (February 2018): 144-151. Full Text
  - Lad, EM, Mukherjee, D, Stinnett, SS, Cousins, SW, Potter, GG, Burke, JR, Farsiu, S, and Whitson, HE. "Evaluation of inner retinal layers as biomarkers in mild cognitive impairment to moderate Alzheimer's disease." PloS one 13, no. 2 (January 2018): e0192646-. Full Text
  - Wong, SS, Vuong, VS, Cunefare, D, Farsiu, S, Moshiri, A, and Yiu, G. "Macular Fluid Reduces Reproducibility of Choroidal Thickness Measurements on Enhanced Depth Optical Coherence Tomography." American journal of ophthalmology 184 (December 2017): 108-114. Full Text
  - DuBose, TB, Cunefare, D, Cole, E, Milanfar, P, Izatt, JA, and Farsiu, S. "Statistical Models of Signal and Noise and Fundamental Limits of Segmentation Accuracy in Retinal Optical Coherence Tomography (Accepted)." IEEE Transactions on Medical Imaging (November 10, 2017). Full Text
  - Yiu, G, Tieu, E, Munevar, C, Wong, B, Cunefare, D, Farsiu, S, Garzel, L, Roberts, J, and Thomasy, SM. "In Vivo Multimodal Imaging of Drusenoid Lesions in Rhesus Macaques." Scientific reports 7, no. 1 (November 3, 2017): 15013-. Full Text
  - Qian, R, Carrasco-Zevallos, OM, Mangalesh, S, Sarin, N, Vajzovic, L, Farsiu, S, Izatt, JA, and Toth, CA. "Characterization of Long Working Distance Optical Coherence Tomography for Imaging of Pediatric Retinal Pathology." Translational vision science & technology 6, no. 5 (October 16, 2017): 12-. Full Text
  - McNabb, RP, Tian, J, Farsiu, S, Izatt, JA, Lad, EM, and Kuo, AN. "Retinal imaging in human autopsy eyes using a custom optical coherence tomography periscope." Biomedical optics express 8, no. 9 (September 2017): 4152-4159. Full Text
  - Cunefare, D, Fang, L, Cooper, RF, Dubra, A, Carroll, J, and Farsiu, S. "Open source software for automatic detection of cone photoreceptors in adaptive optics ophthalmoscopy using convolutional neural networks." Scientific reports 7, no. 1 (July 26, 2017): 6620-. Full Text
  - Wang, J, O'Sullivan, ML, Mukherjee, D, Puñal, VM, Farsiu, S, and Kay, JN. "Anatomy and spatial organization of Müller glia in mouse retina." The Journal of comparative neurology 525, no. 8 (June 2017): 1759-1777. Full Text
  - Fang, L, Cunefare, D, Wang, C, Guymer, RH, Li, S, and Farsiu, S. "Automatic segmentation of nine retinal layer boundaries in OCT images of non-exudative AMD patients using deep learning and graph search." Biomedical optics express 8, no. 5 (May 2017): 2732-2744. Full Text
  - Mukherjee, D, Lad, EM, Vann, RR, Jaffe, SJ, Clemons, TE, Friedlander, M, Chew, EY, Jaffe, GJ, Farsiu, S, and MacTel Study Group, . "Correlation Between Macular Integrity Assessment and Optical Coherence Tomography Imaging of Ellipsoid Zone in Macular Telangiectasia Type 2." Investigative ophthalmology & visual science 58, no. 6 (May 2017): BIO291-BIO299. Full Text
  - Allingham, MJ, Mukherjee, D, Lally, EB, Rabbani, H, Mettu, PS, Cousins, SW, and Farsiu, S. "A Quantitative Approach to Predict Differential Effects of Anti-VEGF Treatment on Diffuse and Focal Leakage in Patients with Diabetic Macular Edema: A Pilot Study." Translational vision science & technology 6, no. 2 (March 21, 2017): 7-. Full Text
  - Willoughby, AS, Chiu, SJ, Silverman, RK, Farsiu, S, Bailey, C, Wiley, HE, Ferris, FL, and Jaffe, GJ. "Platform-Independent Cirrus and Spectralis Thickness Measurements in Eyes with Diabetic Macular Edema Using Fully Automated Software." Translational vision science & technology 6, no. 1 (February 7, 2017): 9-. Full Text
  - Fang, L, Li, S, Cunefare, D, and Farsiu, S. "Segmentation Based Sparse Reconstruction of Optical Coherence Tomography Images." IEEE transactions on medical imaging 36, no. 2 (February 2017): 407-421. Full Text
  - Polans, J, Cunefare, D, Cole, E, Keller, B, Mettu, PS, Cousins, SW, Allingham, MJ, Izatt, JA, and Farsiu, S. "Enhanced visualization of peripheral retinal vasculature with wavefront sensorless adaptive optics optical coherence tomography angiography in diabetic patients." Optics letters 42, no. 1 (January 2017): 17-20. Full Text
  - Polans, J, Keller, B, Carrasco-Zevallos, OM, LaRocca, F, Cole, E, Whitson, HE, Lad, EM, Farsiu, S, and Izatt, JA. "Wide-field retinal optical coherence tomography with wavefront sensorless adaptive optics for enhanced imaging of targeted regions." Biomedical optics express 8, no. 1 (January 2017): 16-37. Full Text
  - Prakalapakorn, SG, Vickers, LA, Estrada, R, Freedman, SF, Tomasi, C, Farsiu, S, and Wallace, DK. "Using an Image Fusion Methodology to Improve Efficiency and Traceability of Posterior Pole Vessel Analysis by ROPtool." The open ophthalmology journal 11 (January 2017): 143-151. Full Text
  - Lezama, J, Mukherjee, D, McNabb, RP, Sapiro, G, Kuo, AN, and Farsiu, S. "Segmentation guided registration of wide field-of-view retinal optical coherence tomography volumes." Biomedical optics express 7, no. 12 (December 2016): 4827-4846. Full Text
  - Smith, RT, Farsiu, S, and Allingham, M. "Understanding RPE Lipofuscin." Investigative ophthalmology & visual science 57, no. 15 (December 2016): 6766-. (Letter) Full Text
  - Veerappan, M, El-Hage-Sleiman, A-KM, Tai, V, Chiu, SJ, Winter, KP, Stinnett, SS, Hwang, TS, Hubbard, GB, Michelson, M, Gunther, R, Wong, WT, Chew, EY, Toth, CA, and Age-related Eye Disease Study 2 Ancillary Spectral Domain Optical Coherence Tomography Study Group, . "Optical Coherence Tomography Reflective Drusen Substructures Predict Progression to Geographic Atrophy in Age-related Macular Degeneration." Ophthalmology 123, no. 12 (December 2016): 2554-2570. Full Text
  - Veerappan, M, El-Hage-Sleiman, A-KM, Tai, V, Chiu, SJ, Winter, KP, Stinnett, SS, Hwang, TS, Hubbard, GB, Michelson, M, Gunther, R, Wong, WT, Chew, EY, Toth, CA, and Age-related Eye Disease Study 2 Ancillary Spectral Domain Optical Coherence Tomography Study Group, . "Optical Coherence Tomography Reflective Drusen Substructures Predict Progression to Geographic Atrophy in Age-related Macular Degeneration." Ophthalmology 123, no. 12 (December 2016): 2554-2570. Full Text
  - Pasricha, ND, Shieh, C, Carrasco-Zevallos, OM, Keller, B, Cunefare, D, Mehta, JS, Farsiu, S, Izatt, JA, Toth, CA, and Kuo, AN. "Needle Depth and Big-Bubble Success in Deep Anterior Lamellar Keratoplasty: An Ex Vivo Microscope-Integrated OCT Study." Cornea 35, no. 11 (November 2016): 1471-1477. Full Text
  - Twa, MD, Schulle, KL, Chiu, SJ, Farsiu, S, and Berntsen, DA. "Validation of Macular Choroidal Thickness Measurements from Automated SD-OCT Image Segmentation." Optometry and vision science : official publication of the American Academy of Optometry 93, no. 11 (November 2016): 1387-1398. Full Text
  - Yiu, G, Vuong, VS, Oltjen, S, Cunefare, D, Farsiu, S, Garzel, L, Roberts, J, and Thomasy, SM. "Effect of Uveal Melanocytes on Choroidal Morphology in Rhesus Macaques and Humans on Enhanced-Depth Imaging Optical Coherence Tomography." Investigative ophthalmology & visual science 57, no. 13 (October 2016): 5764-5771. Full Text
  - Li, G, Mukherjee, D, Navarro, I, Ashpole, NE, Sherwood, JM, Chang, J, Overby, DR, Yuan, F, Gonzalez, P, Kopczynski, CC, Farsiu, S, and Stamer, WD. "Visualization of conventional outflow tissue responses to netarsudil in living mouse eyes." European journal of pharmacology 787 (September 2016): 20-31. Full Text
  - Vuong, VS, Moisseiev, E, Cunefare, D, Farsiu, S, Moshiri, A, and Yiu, G. "Repeatability of Choroidal Thickness Measurements on Enhanced Depth Imaging Optical Coherence Tomography Using Different Posterior Boundaries." American journal of ophthalmology 169 (September 2016): 104-112. Full Text
  - Carrasco-Zevallos, OM, Keller, B, Viehland, C, Shen, L, Waterman, G, Todorich, B, Shieh, C, Hahn, P, Farsiu, S, Kuo, AN, Toth, CA, and Izatt, JA. "Live volumetric (4D) visualization and guidance of in vivo human ophthalmic surgery with intraoperative optical coherence tomography." Scientific reports 6 (August 19, 2016): 31689-. Full Text Open Access Copy
  - Keller, B, Cunefare, D, Grewal, DS, Mahmoud, TH, Izatt, JA, and Farsiu, S. "Length-adaptive graph search for automatic segmentation of pathological features in optical coherence tomography images." Journal of biomedical optics 21, no. 7 (July 2016): 76015-. Full Text
  - Kuo, AN, Verkicharla, PK, McNabb, RP, Cheung, CY, Hilal, S, Farsiu, S, Chen, C, Wong, TY, Ikram, MK, Cheng, CY, Young, TL, Saw, SM, and Izatt, JA. "Posterior Eye Shape Measurement With Retinal OCT Compared to MRI." Investigative ophthalmology & visual science 57, no. 9 (July 2016): OCT196-OCT203. Full Text
  - Todorich, B, Shieh, C, DeSouza, PJ, Carrasco-Zevallos, OM, Cunefare, DL, Stinnett, SS, Izatt, JA, Farsiu, S, Mruthyunjaya, P, Kuo, AN, and Toth, CA. "Impact of Microscope-Integrated OCT on Ophthalmology Resident Performance of Anterior Segment Surgical Maneuvers in Model Eyes." Investigative ophthalmology & visual science 57, no. 9 (July 2016): OCT146-OCT153. Full Text
  - Wu, Z, Cunefare, D, Chiu, E, Luu, CD, Ayton, LN, Toth, CA, Farsiu, S, and Guymer, RH. "Longitudinal Associations Between Microstructural Changes and Microperimetry in the Early Stages of Age-Related Macular Degeneration." Investigative ophthalmology & visual science 57, no. 8 (July 2016): 3714-3722. Full Text
  - Stem, MS, Dunbar, GE, Jackson, GR, Farsiu, S, Pop-Busui, R, and Gardner, TW. "Glucose variability and inner retinal sensory neuropathy in persons with type 1 diabetes mellitus." Eye (London, England) 30, no. 6 (June 2016): 825-832. Full Text
  - Cunefare, D, Cooper, RF, Higgins, B, Katz, DF, Dubra, A, Carroll, J, and Farsiu, S. "Automatic detection of cone photoreceptors in split detector adaptive optics scanning light ophthalmoscope images." Biomedical optics express 7, no. 5 (May 2016): 2036-2050. Full Text
  - Sevilla, MB, McGwin, G, Lad, EM, Clark, M, Yuan, EL, Farsiu, S, Curcio, CA, Owsley, C, and Toth, CA. "Relating Retinal Morphology and Function in Aging and Early to Intermediate Age-related Macular Degeneration Subjects." American journal of ophthalmology 165 (May 2016): 65-77. Full Text
  - Allingham, MJ, Nie, Q, Lad, EM, Izatt, DJ, Mettu, PS, Cousins, SW, and Farsiu, S. "Semiautomatic Segmentation of Rim Area Focal Hyperautofluorescence Predicts Progression of Geographic Atrophy Due to Dry Age-Related Macular Degeneration." Investigative ophthalmology & visual science 57, no. 4 (April 2016): 2283-2289. Full Text
  - Kim, S, Heflin, S, Kresty, LA, Halling, M, Perez, LN, Ho, D, Crose, M, Brown, W, Farsiu, S, Arshavsky, V, and Wax, A. "Analyzing spatial correlations in tissue using angle-resolved low coherence interferometry measurements guided by co-located optical coherence tomography." Biomedical optics express 7, no. 4 (April 2016): 1400-1414. Full Text
  - Bavinger, JC, Dunbar, GE, Stem, MS, Blachley, TS, Kwark, L, Farsiu, S, Jackson, GR, and Gardner, TW. "The Effects of Diabetic Retinopathy and Pan-Retinal Photocoagulation on Photoreceptor Cell Function as Assessed by Dark Adaptometry." Investigative ophthalmology & visual science 57, no. 1 (January 2016): 208-217. Full Text
  - Folgar, FA, Yuan, EL, Sevilla, MB, Chiu, SJ, Farsiu, S, Chew, EY, Toth, CA, and Age Related Eye Disease Study 2 Ancillary Spectral-Domain Optical Coherence Tomography Study Group, . "Drusen Volume and Retinal Pigment Epithelium Abnormal Thinning Volume Predict 2-Year Progression of Age-Related Macular Degeneration." Ophthalmology 123, no. 1 (January 2016): 39-50.e1. Full Text
  - Knoll, B, Simonett, J, Volpe, NJ, Farsiu, S, Ward, M, Rademaker, A, Weintraub, S, and Fawzi, AA. "Retinal nerve fiber layer thickness in amnestic mild cognitive impairment: Case-control study and meta-analysis." Alzheimer's & dementia (Amsterdam, Netherlands) 4 (January 2016): 85-93. Full Text
  - LaRocca, F, Nankivil, D, DuBose, T, Toth, CA, Farsiu, S, and Izatt, JA. "In vivo cellular-resolution retinal imaging in infants and children using an ultracompact handheld probe." Nature photonics 10 (January 2016): 580-584. Full Text
  - Simonett, JM, Huang, R, Siddique, N, Farsiu, S, Siddique, T, Volpe, NJ, and Fawzi, AA. "Macular sub-layer thinning and association with pulmonary function tests in Amyotrophic Lateral Sclerosis." Scientific reports 6 (January 2016): 29187-. Full Text
  - Boussommier-Calleja, A, Li, G, Wilson, A, Ziskind, T, Scinteie, OE, Ashpole, NE, Sherwood, JM, Farsiu, S, Challa, P, Gonzalez, P, Downs, JC, Ethier, CR, Stamer, WD, and Overby, DR. "Physical Factors Affecting Outflow Facility Measurements in Mice." Investigative ophthalmology & visual science 56, no. 13 (December 2015): 8331-8339. Full Text
  - Estrada, R, Allingham, MJ, Mettu, PS, Cousins, SW, Tomasi, C, and Farsiu, S. "Retinal Artery-Vein Classification via Topology Estimation." IEEE transactions on medical imaging 34, no. 12 (December 2015): 2518-2534. Full Text
  - Estrada, R, Tomasi, C, Schmidler, SC, and Farsiu, S. "Tree Topology Estimation." IEEE transactions on pattern analysis and machine intelligence 37, no. 8 (August 2015): 1688-1701. Full Text
  - Nam, DH, Desouza, PJ, Hahn, P, Tai, V, Sevilla, MB, Tran-Viet, D, Cunefare, D, Farsiu, S, Izatt, JA, and Toth, CA. "INTRAOPERATIVE SPECTRAL DOMAIN OPTICAL COHERENCE TOMOGRAPHY IMAGING AFTER INTERNAL LIMITING MEMBRANE PEELING IN IDIOPATHIC EPIRETINAL MEMBRANE WITH CONNECTING STRANDS." Retina (Philadelphia, Pa.) 35, no. 8 (August 2015): 1622-1630. Full Text
  - Hahn, P, Carrasco-Zevallos, O, Cunefare, D, Migacz, J, Farsiu, S, Izatt, JA, and Toth, CA. "Intrasurgical Human Retinal Imaging With Manual Instrument Tracking Using a Microscope-Integrated Spectral-Domain Optical Coherence Tomography Device." Translational vision science & technology 4, no. 4 (July 2015): 1-. Full Text
  - Fang, L, Li, S, Kang, X, Izatt, JA, and Farsiu, S. "3-D Adaptive Sparsity Based Image Compression With Applications to Optical Coherence Tomography." IEEE transactions on medical imaging 34, no. 6 (June 2015): 1306-1320. Full Text
  - Goldhagen, BE, Bhatti, MT, Srinivasan, PP, Chiu, SJ, Farsiu, S, and El-Dairi, MA. "Retinal atrophy in eyes with resolved papilledema detected by optical coherence tomography." Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society 35, no. 2 (June 2015): 122-126. Full Text
  - Boynton, GE, Stem, MS, Kwark, L, Jackson, GR, Farsiu, S, and Gardner, TW. "Multimodal characterization of proliferative diabetic retinopathy reveals alterations in outer retinal function and structure." Ophthalmology 122, no. 5 (May 2015): 957-967. Full Text
  - Chiu, SJ, Allingham, MJ, Mettu, PS, Cousins, SW, Izatt, JA, and Farsiu, S. "Kernel regression based segmentation of optical coherence tomography images with diabetic macular edema." Biomedical optics express 6, no. 4 (April 2015): 1172-1194. Full Text
  - Rothman, AL, Sevilla, MB, Freedman, SF, Tong, AY, Tai, V, Tran-Viet, D, Farsiu, S, Toth, CA, and El-Dairi, MA. "Assessment of retinal nerve fiber layer thickness in healthy, full-term neonates." American journal of ophthalmology 159, no. 4 (April 2015): 803-811. Full Text
  - Yiu, G, Chiu, SJ, Petrou, PA, Stinnett, S, Sarin, N, Farsiu, S, Chew, EY, Wong, WT, and Toth, CA. "Relationship of central choroidal thickness with age-related macular degeneration status." American journal of ophthalmology 159, no. 4 (April 2015): 617-626. Full Text
  - Rabbani, H, Allingham, MJ, Mettu, PS, Cousins, SW, and Farsiu, S. "Fully automatic segmentation of fluorescein leakage in subjects with diabetic macular edema." Investigative ophthalmology & visual science 56, no. 3 (January 29, 2015): 1482-1492. Full Text
  - Srinivasan, PP, Kim, LA, Mettu, PS, Cousins, SW, Comer, GM, Izatt, JA, and Farsiu, S. "Fully automated detection of diabetic macular edema and dry age-related macular degeneration from optical coherence tomography images." Biomedical optics express 5, no. 10 (October 2014): 3568-3577. Full Text
  - Yiu, G, Manjunath, V, Chiu, SJ, Farsiu, S, and Mahmoud, TH. "Effect of anti-vascular endothelial growth factor therapy on choroidal thickness in diabetic macular edema." American journal of ophthalmology 158, no. 4 (October 2014): 745-751.e2. Full Text
  - LaRocca, F, Nankivil, D, Farsiu, S, and Izatt, JA. "True color scanning laser ophthalmoscopy and optical coherence tomography handheld probe." Biomedical optics express 5, no. 9 (September 2014): 3204-3216. Full Text
  - Nankivil, D, Dhalla, A-H, Gahm, N, Shia, K, Farsiu, S, and Izatt, JA. "Coherence revival multiplexed, buffered swept source optical coherence tomography: 400 kHz imaging with a 100 kHz source." Optics letters 39, no. 13 (July 2014): 3740-3743. Full Text
  - Li, G, Farsiu, S, Chiu, SJ, Gonzalez, P, Lütjen-Drecoll, E, Overby, DR, and Stamer, WD. "Pilocarpine-induced dilation of Schlemm's canal and prevention of lumen collapse at elevated intraocular pressures in living mice visualized by OCT." Investigative ophthalmology & visual science 55, no. 6 (March 4, 2014): 3737-3746. Full Text
  - Polans, J, McNabb, RP, Izatt, JA, and Farsiu, S. "Compressed wavefront sensing." Optics letters 39, no. 5 (March 2014): 1189-1192. Full Text
  - Srinivasan, PP, Heflin, SJ, Izatt, JA, Arshavsky, VY, and Farsiu, S. "Automatic segmentation of up to ten layer boundaries in SD-OCT images of the mouse retina with and without missing layers due to pathology." Biomedical optics express 5, no. 2 (February 2014): 348-365. Full Text
  - Yiu, G, Pecen, P, Sarin, N, Chiu, SJ, Farsiu, S, Mruthyunjaya, P, and Toth, CA. "Characterization of the choroid-scleral junction and suprachoroidal layer in healthy individuals on enhanced-depth imaging optical coherence tomography." JAMA Ophthalmol 132, no. 2 (February 2014): 174-181. Full Text Link to Item
  - Farsiu, S, Chiu, SJ, O'Connell, RV, Folgar, FA, Yuan, E, Izatt, JA, Toth, CA, and Age-Related Eye Disease Study 2 Ancillary Spectral Domain Optical Coherence Tomography Study Group, . "Quantitative classification of eyes with and without intermediate age-related macular degeneration using optical coherence tomography." Ophthalmology 121, no. 1 (January 2014): 162-172. Full Text Link to Item
  - Folgar, FA, Yuan, EL, Farsiu, S, and Toth, CA. "Lateral and axial measurement differences between spectral-domain optical coherence tomography systems." Journal of biomedical optics 19, no. 1 (January 2014): 16014-. Full Text
  - Li, G, Farsiu, S, Qiu, J, Dixon, A, Song, C, McKinnon, SJ, Yuan, F, Gonzalez, P, and Stamer, WD. "Disease progression in iridocorneal angle tissues of BMP2-induced ocular hypertensive mice with optical coherence tomography." Molecular vision 20 (January 2014): 1695-1709.
  - Bowes Rickman, C, Farsiu, S, Toth, CA, and Klingeborn, M. "Dry age-related macular degeneration: mechanisms, therapeutic targets, and imaging. (Published online)" Invest Ophthalmol Vis Sci 54, no. 14 (December 13, 2013): ORSF68-ORSF80. (Review) Full Text Link to Item
  - Lee, JY, Chiu, SJ, Srinivasan, PP, Izatt, JA, Toth, CA, Farsiu, S, and Jaffe, GJ. "Fully automatic software for retinal thickness in eyes with diabetic macular edema from images acquired by cirrus and spectralis systems. (Published online)" Invest Ophthalmol Vis Sci 54, no. 12 (November 15, 2013): 7595-7602. Full Text Link to Item
  - Fang, L, Li, S, McNabb, RP, Nie, Q, Kuo, AN, Toth, CA, Izatt, JA, and Farsiu, S. "Fast acquisition and reconstruction of optical coherence tomography images via sparse representation." IEEE Trans Med Imaging 32, no. 11 (November 2013): 2034-2049. Full Text Link to Item
  - LaRocca, F, Nankivil, D, Farsiu, S, and Izatt, JA. "Handheld simultaneous scanning laser ophthalmoscopy and optical coherence tomography system." BIOMEDICAL OPTICS EXPRESS 4, no. 11 (November 1, 2013): 2307-2321. Full Text Link to Item
  - Cabrera, MT, O'Connell, RV, Toth, CA, Maldonado, RS, Tran-Viet, D, Allingham, MJ, Chiu, SJ, Farsiu, S, Maradiaga Panayotti, GM, Swamy, GK, and Freedman, SF. "Macular findings in healthy full-term Hispanic newborns observed by hand-held spectral-domain optical coherence tomography." Ophthalmic Surg Lasers Imaging Retina 44, no. 5 (September 2013): 448-454. Full Text Link to Item
  - Kuo, AN, McNabb, RP, Chiu, SJ, El-Dairi, MA, Farsiu, S, Toth, CA, and Izatt, JA. "Correction of ocular shape in retinal optical coherence tomography and effect on current clinical measures." Am J Ophthalmol 156, no. 2 (August 2013): 304-311. Full Text Link to Item
  - LaRocca, F, Dhalla, A-H, Kelly, MP, Farsiu, S, and Izatt, JA. "Optimization of confocal scanning laser ophthalmoscope design." J Biomed Opt 18, no. 7 (July 2013): 076015-. Full Text Link to Item
  - Moreno, TA, O'Connell, RV, Chiu, SJ, Farsiu, S, Cabrera, MT, Maldonado, RS, Tran-Viet, D, Freedman, SF, Wallace, DK, and Toth, CA. "Choroid development and feasibility of choroidal imaging in the preterm and term infants utilizing SD-OCT. (Published online)" Invest Ophthalmol Vis Sci 54, no. 6 (June 14, 2013): 4140-4147. Full Text Link to Item
  - Chiu, SJ, Lokhnygina, Y, Dubis, AM, Dubra, A, Carroll, J, Izatt, JA, and Farsiu, S. "Automatic cone photoreceptor segmentation using graph theory and dynamic programming. (Published online)" Biomed Opt Express 4, no. 6 (June 1, 2013): 924-937. Full Text Link to Item
  - Hendargo, HC, Estrada, R, Chiu, SJ, Tomasi, C, Farsiu, S, and Izatt, JA. "Automated non-rigid registration and mosaicing for robust imaging of distinct retinal capillary beds using speckle variance optical coherence tomography. (Published online)" Biomed Opt Express 4, no. 6 (June 1, 2013): 803-821. Full Text Link to Item
  - Christenbury, JG, Folgar, FA, O'Connell, RV, Chiu, SJ, Farsiu, S, Toth, CA, and Age-related Eye Disease Study 2 Ancillary Spectral Domain Optical Coherence Tomography Study Group, . "Progression of intermediate age-related macular degeneration with proliferation and inner retinal migration of hyperreflective foci." Ophthalmology 120, no. 5 (May 2013): 1038-1045. Full Text Link to Item
  - Ehlers, JP, Tao, YK, Farsiu, S, Maldonado, R, Izatt, JA, and Toth, CA. "Visualization of real-time intraoperative maneuvers with a microscope-mounted spectral domain optical coherence tomography system." Retina 33, no. 1 (January 2013): 232-236. Full Text Link to Item
  - McNabb, RP, LaRocca, F, Farsiu, S, Kuo, AN, and Izatt, JA. "Distributed scan SDOCT improves post refractive surgery corneal biometry." Biomedical Optics, BIOMED 2012 (December 1, 2012).
  - Vajzovic, L, Hendrickson, AE, O'Connell, RV, Clark, LA, Tran-Viet, D, Possin, D, Chiu, SJ, Farsiu, S, and Toth, CA. "Maturation of the human fovea: correlation of spectral-domain optical coherence tomography findings with histology." Am J Ophthalmol 154, no. 5 (November 2012): 779-789.e2. Full Text Link to Item
  - McNabb, RP, Larocca, F, Farsiu, S, Kuo, AN, and Izatt, JA. "Distributed scanning volumetric SDOCT for motion corrected corneal biometry." Biomed Opt Express 3, no. 9 (September 1, 2012): 2050-2065. Full Text Link to Item
  - Folgar, FA, Chow, JH, Farsiu, S, Wong, WT, Schuman, SG, O'Connell, RV, Winter, KP, Chew, EY, Hwang, TS, Srivastava, SK, Harrington, MW, Clemons, TE, and Toth, CA. "Spatial correlation between hyperpigmentary changes on color fundus photography and hyperreflective foci on SDOCT in intermediate AMD. (Published online)" Invest Ophthalmol Vis Sci 53, no. 8 (July 9, 2012): 4626-4633. Full Text Link to Item
  - Yanni, SE, Wang, J, Chan, M, Carroll, J, Farsiu, S, Leffler, JN, Spencer, R, and Birch, EE. "Foveal avascular zone and foveal pit formation after preterm birth." Br J Ophthalmol 96, no. 7 (July 2012): 961-966. Full Text Link to Item
  - Kuo, AN, McNabb, RP, Zhao, M, Larocca, F, Stinnett, SS, Farsiu, S, and Izatt, JA. "Corneal biometry from volumetric SDOCT and comparison with existing clinical modalities." Biomed Opt Express 3, no. 6 (June 1, 2012): 1279-1290. Full Text Link to Item
  - Chiu, SJ, Toth, CA, Bowes Rickman, C, Izatt, JA, and Farsiu, S. "Automatic segmentation of closed-contour features in ophthalmic images using graph theory and dynamic programming." Biomed Opt Express 3, no. 5 (May 1, 2012): 1127-1140. Full Text Link to Item
  - Fang, L, Li, S, Nie, Q, Izatt, JA, Toth, CA, and Farsiu, S. "Sparsity based denoising of spectral domain optical coherence tomography images." Biomed Opt Express 3, no. 5 (May 1, 2012): 927-942. Full Text Link to Item
  - Maldonado, RS, O'Connell, R, Ascher, SB, Sarin, N, Freedman, SF, Wallace, DK, Chiu, SJ, Farsiu, S, Cotten, M, and Toth, CA. "Spectral-domain optical coherence tomographic assessment of severity of cystoid macular edema in retinopathy of prematurity." Arch Ophthalmol 130, no. 5 (May 2012): 569-578. Full Text Link to Item
  - Lin, P, Mettu, PS, Pomerleau, DL, Chiu, SJ, Maldonado, R, Stinnett, S, Toth, CA, Farsiu, S, and Mruthyunjaya, P. "Image inversion spectral-domain optical coherence tomography optimizes choroidal thickness and detail through improved contrast. (Published online)" Invest Ophthalmol Vis Sci 53, no. 4 (April 6, 2012): 1874-1882. Full Text Link to Item
  - Estrada, R, Tomasi, C, Cabrera, MT, Wallace, DK, Freedman, SF, and Farsiu, S. "Exploratory Dijkstra forest based automatic vessel segmentation: applications in video indirect ophthalmoscopy (VIO)." Biomed Opt Express 3, no. 2 (February 1, 2012): 327-339. Full Text Link to Item
  - Chiu, SJ, Izatt, JA, O'Connell, RV, Winter, KP, Toth, CA, and Farsiu, S. "Validated automatic segmentation of AMD pathology including drusen and geographic atrophy in SD-OCT images. (Published online)" Invest Ophthalmol Vis Sci 53, no. 1 (January 5, 2012): 53-61. Full Text Link to Item
  - Cabrera, MT, Maldonado, RS, Toth, CA, O'Connell, RV, Chen, BB, Chiu, SJ, Farsiu, S, Wallace, DK, Stinnett, SS, Panayotti, GMM, Swamy, GK, and Freedman, SF. "Subfoveal fluid in healthy full-term newborns observed by handheld spectral-domain optical coherence tomography." Am J Ophthalmol 153, no. 1 (January 2012): 167-75.e3. Full Text Link to Item
  - Maldonado, RS, O'Connell, RV, Sarin, N, Freedman, SF, Wallace, DK, Cotten, CM, Winter, KP, Stinnett, S, Chiu, SJ, Izatt, JA, Farsiu, S, and Toth, CA. "Dynamics of human foveal development after premature birth." Ophthalmology 118, no. 12 (December 2011): 2315-2325. Full Text Link to Item
  - Ehlers, JP, Kernstine, K, Farsiu, S, Sarin, N, Maldonado, R, and Toth, CA. "Analysis of pars plana vitrectomy for optic pit-related maculopathy with intraoperative optical coherence tomography: a possible connection with the vitreous cavity." Arch Ophthalmol 129, no. 11 (November 2011): 1483-1486. Full Text Link to Item
  - Estrada, R, Tomasi, C, Cabrera, MT, Wallace, DK, Freedman, SF, and Farsiu, S. "Enhanced video indirect ophthalmoscopy (VIO) via robust mosaicing." Biomed Opt Express 2, no. 10 (October 1, 2011): 2871-2887. Full Text Link to Item
  - Ding, J-D, Johnson, LV, Herrmann, R, Farsiu, S, Smith, SG, Groelle, M, Mace, BE, Sullivan, P, Jamison, JA, Kelly, U, Harrabi, O, Bollini, SS, Dilley, J, Kobayashi, D, Kuang, B, Li, W, Pons, J, Lin, JC, and Bowes Rickman, C. "Anti-amyloid therapy protects against retinal pigmented epithelium damage and vision loss in a model of age-related macular degeneration." Proc Natl Acad Sci U S A 108, no. 28 (July 12, 2011): E279-E287. Full Text Link to Item
  - Ding, J, Herrmann, LJR, Farsiu, S, Smith, S, Groelle, M, Mace, B, Sullivan, P, Jamison, J, Kelly, U, Harrabi, O, Bollini, S, Dilley, J, Kobayashi, D, Kuang, B, Li, W, Pons, J, Lin, J, and Rickman, CB. "Anti-amyloid immunotherapy protects against RPE damage and loss of visual function in a mouse model of age-related macular degeneration." Proceedings of the National Academy of Sciences (PNAS). 108, no. 28 (June 2011). (Academic Article) Link to Item
  - Larocca, F, Chiu, SJ, McNabb, RP, Kuo, AN, Izatt, JA, and Farsiu, S. "Robust automatic segmentation of corneal layer boundaries in SDOCT images using graph theory and dynamic programming." Biomed Opt Express 2, no. 6 (June 1, 2011): 1524-1538. Full Text Link to Item
  - Ehlers, JP, Tao, YK, Farsiu, S, Maldonado, R, Izatt, JA, and Toth, CA. "Integration of a spectral domain optical coherence tomography system into a surgical microscope for intraoperative imaging. (Published online)" Invest Ophthalmol Vis Sci 52, no. 6 (May 16, 2011): 3153-3159. Full Text Link to Item
  - Reidel, B, Thompson, JW, Farsiu, S, Moseley, MA, Skiba, NP, and Arshavsky, VY. "Proteomic profiling of a layered tissue reveals unique glycolytic specializations of photoreceptor cells." Mol Cell Proteomics 10, no. 3 (March 2011): M110.002469-. Full Text Link to Item
  - Ehlers, JP, Gupta, PK, Farsiu, S, Maldonado, R, Kim, T, Toth, CA, and Mruthyunjaya, P. "Evaluation of contrast agents for enhanced visualization in optical coherence tomography." Invest Ophthalmol Vis Sci 51, no. 12 (December 2010): 6614-6619. Full Text Link to Item
  - Jain, N, Farsiu, S, Khanifar, AA, Bearelly, S, Smith, RT, Izatt, JA, and Toth, CA. "Quantitative comparison of drusen segmented on SD-OCT versus drusen delineated on color fundus photographs." Invest Ophthalmol Vis Sci 51, no. 10 (October 2010): 4875-4883. Full Text Link to Item
  - Robinson, MD, Toth, CA, Lo, JY, and Farsiu, S. "Efﬁcient fourier-wavelet super-resolution." IEEE Trans Image Process 19, no. 10 (October 2010): 2669-2681. Full Text Link to Item
  - Chiu, SJ, Li, XT, Nicholas, P, Toth, CA, Izatt, JA, and Farsiu, S. "Automatic segmentation of seven retinal layers in SDOCT images congruent with expert manual segmentation." Opt Express 18, no. 18 (August 30, 2010): 19413-19428. Open Access Copy Link to Item
  - Tao, YK, Farsiu, S, and Izatt, JA. "Interlaced spectrally encoded confocal scanning laser ophthalmoscopy and spectral domain optical coherence tomography. (Published online)" Biomed Opt Express 1, no. 2 (August 2, 2010): 431-440. Full Text Link to Item
  - Chavala, SH, Farsiu, S, Maldonado, R, Wallace, DK, Freedman, SF, and Toth, CA. "Insights into advanced retinopathy of prematurity using handheld spectral domain optical coherence tomography imaging." Ophthalmology 116, no. 12 (December 2009): 2448-2456. Full Text Link to Item
  - Dayani, PN, Maldonado, R, Farsiu, S, and Toth, CA. "Intraoperative use of handheld spectral domain optical coherence tomography imaging in macular surgery." Retina 29, no. 10 (November 2009): 1457-1468. Full Text Link to Item
  - Schuman, SG, Koreishi, AF, Farsiu, S, Jung, S-H, Izatt, JA, and Toth, CA. "Photoreceptor layer thinning over drusen in eyes with age-related macular degeneration imaged in vivo with spectral-domain optical coherence tomography." Ophthalmology 116, no. 3 (March 2009): 488-496.e2. Full Text Link to Item
  - Scott, AW, Farsiu, S, Enyedi, LB, Wallace, DK, and Toth, CA. "Imaging the infant retina with a hand-held spectral-domain optical coherence tomography device." Am J Ophthalmol 147, no. 2 (February 2009): 364-373.e2. Full Text Link to Item
  - Chong, GT, Farsiu, S, Freedman, SF, Sarin, N, Koreishi, AF, Izatt, JA, and Toth, CA. "Abnormal foveal morphology in ocular albinism imaged with spectral-domain optical coherence tomography." Arch Ophthalmol 127, no. 1 (January 2009): 37-44. Full Text Link to Item
  - Chou, N, Izatt, JA, and Farsiu, S. "Generalized pseudo-polar fourier grids and applications in registering ophthalmic optical coherence tomography images." Conference Record - Asilomar Conference on Signals, Systems and Computers (2009): 807-811. Full Text
  - Robinson, D, Farsiu, S, and Milanfar, P. "Optimal registration of aliased images using variable projection with applications to super-resolution." Computer Journal 52, no. 1 (2009): 31-42. Full Text
  - Wang, X, Farsiu, S, Milanfar, P, and Shakouri, A. "Power trace: An efficient method for extracting the power dissipation profile in an IC chip from its temperature map." IEEE Transactions on Components and Packaging Technologies 32, no. 2 (2009): 309-316. Full Text
  - Takeda, H, Farsiu, S, and Milanfar, P. "Deblurring using regularized locally adaptive kernel regression." IEEE Trans Image Process 17, no. 4 (April 2008): 550-563. Full Text Link to Item
  - Farsiu, S, Christofferson, J, Eriksson, B, Milanfar, P, Friedlander, B, Shakouri, A, and Nowak, R. "Statistical detection and imaging of objects hidden in turbid media using ballistic photons." Appl Opt 46, no. 23 (August 10, 2007): 5805-5822. Link to Item
  - Takeda, H, Farsiu, S, and Milanfar, P. "Kernel regression for image processing and reconstruction." IEEE Trans Image Process 16, no. 2 (February 2007): 349-366. Link to Item
  - Takeda, H, Farsiu, S, and Milanfar, P. "Higher order bilateral filters and their properties." Proceedings of SPIE - The International Society for Optical Engineering 6498 (2007). Full Text
  - Wang, X, Shakouri, A, Farsiu, S, and Milanfar, P. "Extraction of power dissipation profile in an IC chip from temperature map." Annual IEEE Semiconductor Thermal Measurement and Management Symposium (2007): 51-56. Full Text
  - Farsiu, S, Elad, M, and Milanfar, P. "Multiframe demosaicing and super-resolution of color images." IEEE Trans Image Process 15, no. 1 (January 2006): 141-159. Link to Item
  - Farsiu, S, Elad, M, and Milanfar, P. "A practical approach to super-resolution." Proceedings of SPIE - The International Society for Optical Engineering 6077 (2006). Full Text
  - Farsiu, S, Elad, M, and Milanfar, P. "Video-to-video dynamic super-resolution for grayscale and color sequences." Eurasip Journal on Applied Signal Processing 2006 (2006). Full Text
  - Farsiu, S, and Milanfar, P. "Multi-scale statistical detection and ballistic imaging through turbid media." Proceedings - International Conference on Image Processing, ICIP 3 (2006): III537-III540. Full Text
  - Takeda, H, Farsiu, S, and Milanfar, P. "Robust kernel regression for restoration and reconstruction of images from sparse noisy data." Proceedings - International Conference on Image Processing, ICIP (2006): 1257-1260. Full Text
  - Takeda, H, Farsiu, S, and Milanfar, P. "Regularized kernel regression for image deblurring." Conference Record - Asilomar Conference on Signals, Systems and Computers (2006): 1914-1918. Full Text
  - Farsiu, S, Elad, M, and Milanfar, P. "Constrained, globally optimal, multi-frame motion estimation." IEEE Workshop on Statistical Signal Processing Proceedings 2005 (2005): 1396-1401.
  - Takeda, H, Farsiu, S, and Milanfar, P. "Image denoising by adaptive kernel regression." Conference Record - Asilomar Conference on Signals, Systems and Computers 2005 (2005): 1660-1665.
  - Farsiu, S, Robinson, MD, Elad, M, and Milanfar, P. "Fast and robust multiframe super resolution." IEEE Trans Image Process 13, no. 10 (October 2004): 1327-1344. Link to Item
  - Farsiu, S, Elad, M, and Milanfar, P. "Multi-frame demosaicing and super-resolution from under-sampled color images." Proceedings of SPIE - The International Society for Optical Engineering 5299 (2004): 222-233. Full Text
  - Farsiu, S, Robinson, D, Elad, M, and Milanfar, P. "Dynamic demosaicing and color super-resolution of video sequences." Proceedings of SPIE - The International Society for Optical Engineering 5562 (2004): 169-178. Full Text
  - Farsiu, S, Robinson, D, Elad, M, and Milanfar, P. "Advances and challenges in super-resolution." International Journal of Imaging Systems and Technology 14, no. 2 (2004): 47-57. Full Text
  - Farsiu, S, Robinson, D, Elad, M, and Milanfar, P. "Robust Shift and Add Approach to Super-Resolution." Proceedings of SPIE - The International Society for Optical Engineering 5203 (2003): 121-130. Full Text
  - Farsiu, S, Robinson, D, Elad, M, and Milanfar, P. "Fast and robust super-resolution." IEEE International Conference on Image Processing 2 (2003): 291-294.
  - Rajimehr, R, Farsiu, S, Kouhsari, LM, Bidari, A, Lucas, C, Yousefian, S, and Bahrami, F. "Prediction of lupus nephritis in patients with systemic lupus erythematosus using artificial neural networks." Lupus 11, no. 8 (2002): 485-492. Full Text Link to Item
- Other Articles
  - McNabb, RP, Farsiu, S, Stinnett, SS, Izatt, JA, and Kuo, AN. "Reply." Ophthalmology 123, no. 1 (January 2016): e6-e7. (Letter) Full Text
  - McNabb, RP, Farsiu, S, Stinnett, SS, Izatt, JA, and Kuo, AN. "Re: McNabb et al.: Optical coherence tomography accurately measures corneal power change from laser refractive surgery (Ophthalmology 2015;122:677-86) REPLY." OPHTHALMOLOGY 123, no. 1 (January 2016): E6-E7. Full Text Link to Item
  - Folgar, FA, Yuan, EL, Farsiu, S, and Toth, CA. "Errata: Lateral and axial measurement differences between spectral-domain optical coherence tomography systems." Journal of biomedical optics 20, no. 5 (May 2015): 59802-. Full Text
  - Folgar, FA, Yuan, EL, Farsiu, S, and Toth, CA. "Erratum: Lateral and axial measurement differences between spectral-domain optical coherence tomography systems(Journal of Biomedical Optics 19:1 016014 (2014))." Journal of Biomedical Optics 20, no. 5 (May 1, 2015).
  - Dayani, PN, Maldonado, R, Farsiu, S, and Toth, CA. "Erratum: Intraoperative use of handheld spectral domain optical coherence tomography imaging in macular surgery (Retina (2009) 29:10 (1457-1468))." Retina 31, no. 6 (2011): 1236--. Full Text
  - Scott, AW, Farsiu, S, Enyedi, LB, Wallace, DK, and Toth, CA. "Retinal Morphologic Features in Shaken Baby Syndrome Evaluated by Optical Coherence Tomography REPLY." AMERICAN JOURNAL OF OPHTHALMOLOGY 147, no. 6 (June 2009): 1102-1103. Full Text Link to Item
  - Scott, AW, Farsiu, S, Enyedi, LB, Wallace, DK, and Toth, CA. "Reply." American Journal of Ophthalmology 147, no. 6 (2009): 1102-1103. Full Text
  - Khanifar, AA, and Farsiu, S. "Spectral-domain OCT in practice." Retina Today , no. MAY (2008): 49-51.
  - Robinson, MD, Farsiu, S, Lo, JY, Milanfar, P, and Toth, CA. "Efficient registration of aliased x-ray images." Conference Record - Asilomar Conference on Signals, Systems and Computers (2007): 215-219. Full Text
Teaching & Mentoring
Recent Courses
Advising & Mentoring
- I am proud of the students that have collaborated with me at the Vision and Image Processing Laboratory and their outstanding scientific achievements. My most recent PhD graduate, Stephanie J. Chiu, co-authored over 20 journal papers during her tenure in my lab. My most recent Pratt Fellow undergraduate student, Pratul P. Srinivasan, published four journal papers including two first-authored papers during his tenure in my lab.
Scholarly, Clinical, & Service Activities
Outreach & Engaged Scholarship
- Bass Connections Faculty Team Member. Art, Vision and the Brain: An Exploration of Color and Brightness. July 2014 - May 2015 2014 - 2015

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