Research Interests
Focused on medical imaging and machine learning to improve the overall health and vision outcome of patients with ocular and neurological diseases (e.g., age-related macular degeneration, diabetic retinopathy, Alzheimer, and ALS) through earlier and personalized therapy.
Selected Grants
Defining the underlying causes of retinal degeneration in CRB1 disease
ResearchCo-Principal Investigator · Awarded by Foundation Fighting Blindness, Inc · 2024 - 2029Quantitative assessment of glaucomatous conventional outflow dynamics
ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2019 - 2029Automated Quantitative Ulcer Analysis (AQUA): Diagnosing Organism Types
ResearchPrincipal Investigator · Awarded by University of Michigan · 2024 - 2028Blink, Lacrimation, and Nociception: Precision Mapping and Integrated Atlas Generation of Corneal Trigeminal Afferents in Mice and Humans
ResearchCo-Principal Investigator · Awarded by National Institutes of Health · 2022 - 2027Elucidating perifoveal vascular development in infants
ResearchCo Investigator · Awarded by National Institutes of Health · 2022 - 2027Retinal Light Scattering Measurements as a Clinical Biomarker of Alzheimer's Disease
ResearchCo Investigator · Awarded by National Institute on Aging · 2022 - 2027NAC Attack, a phase-3, multicenter, randomized, placebo-controlled trial with retinitis pigmentosa: OCT Reading Center
Clinical TrialCo-Principal Investigator · Awarded by National Institutes of Health · 2022 - 2027Automated Software for Analysis of Adaptive Optics Scanning Optical Coherence Tomography Images
ResearchPrincipal Investigator · Awarded by Foundation Fighting Blindness, Inc · 2021 - 2026Soft drusen in rhesus macaques as a nonhuman primate model of early age-related macular degeneration
ResearchPrincipal Investigator · Awarded by University of California - Davis · 2021 - 2025OCT measurement of trabecular meshwork function in vivo
ResearchCo Investigator · Awarded by Georgia Institute of Technology · 2020 - 2025Quantifying Microbial Keratitis Features to Predict Outcomes
ResearchPrincipal Investigator · Awarded by University of Michigan · 2020 - 2024Screening for pediatric retinal diseases using artificial intelligence and wide-field fundus imaging
ResearchCollaborator · Awarded by VitreoRetinal Surgery Foundation · 2021 - 2023The BCI (Brain Computer Interface) Glaucoma Study: Objective Home-Based Detection of Progressive Visual Function Loss in Glaucoma
ResearchCo Investigator · Awarded by National Institutes of Health · 2019 - 2023Application of deep machine learning for identifying structural and functional deficits in retinitis pigmentosa
ResearchPrincipal Investigator · Awarded by Retina Foundation of the Southwest · 2019 - 2022Advanced a/LCI systems for improved clinical utility
ResearchCollaborating Investigator · Awarded by National Institutes of Health · 2016 - 2022Artificial Intelligence-aided Screening of Potentially Blinding Pediatric Retinal Diseases
FellowshipPrincipal Investigator · Awarded by Hartwell Foundation · 2020 - 2022Compressive aperture super-resolution in vivo microscopy
ResearchCo-Principal Investigator · Awarded by National Science Foundation · 2019 - 2022Portable motion-stabilized optical coherence tomography for eye care in acute care settings
ResearchCo Investigator · Awarded by National Institutes of Health · 2018 - 2022Handheld Portable Adaptive Optics Optical Coherence Tomography for Imaging Young Children
ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2019 - 2022Using Machine Learning to Identify Eye Disease in Optical Coherence Tomography Images Obtained from a Robotically-Aligned Scanner
FellowshipCo-Mentor · Awarded by Research To Prevent Blindness, Inc. · 2021 - 2021Psychophysics-Guided Signal Processing for Retinal Prosthetics
ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2018 - 2021A Deep Learning Model to Objectively Quantify Glaucomatous Damage on Fundus Photographs: Validation and Application to a Teleophthalmology Screening Program
ResearchCollaborator · Awarded by National Institutes of Health · 2020 - 2021Novel Experimental Model for Pseudoexfolliation Syndrome
ResearchBioinformatics Specialist · Awarded by National Institutes of Health · 2018 - 2020Training in Medical Imaging
Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2003 - 2020Coherent light scattering for early detection of Alzheimer's disease
ResearchCo Investigator · Awarded by National Institutes of Health · 2017 - 2020Handheld Portable Adaptive Optics Scanning Laser Ophthalmoscope for Imaging Young Children
ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2016 - 2019NCS-FO:Real-time optical readout and control of population neural activity with cellular resolution
ResearchCo-Principal Investigator · Awarded by National Science Foundation · 2015 - 2019RPB: 2014 Nelson Trust Award
ResearchCollaborator · Awarded by Research To Prevent Blindness, Inc. · 2014 - 2019Automated Software for Analysis of Adaptive Optics Scanning Laser Ophthalmoscopy Images
ResearchPrincipal Investigator · Awarded by Foundation Fighting Blindness, Inc · 2016 - 2019Flavoprotein Autofluorescence Imaging in AMD
ResearchCo Investigator · Awarded by National Institutes of Health · 2015 - 2018Computer Aided Classification of Diabetic Macular Edema
ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2012 - 2018Temporal dynamics of retinal ganglion cell neurodegeneration in glaucoma
ResearchCollaborator · Awarded by National Institutes of Health · 2015 - 2018Intraoperative OCT Guidance of Intraocular Surgery
ResearchCo Investigator · Awarded by National Institutes of Health · 2013 - 2017OCT measurement of TM/SC stiffness in living mice
ResearchCollaborator · Awarded by BrightFocus Foundation · 2015 - 2017Smartphone Ophthalmoscope Lens Vascularity
ResearchPrincipal Investigator · Awarded by Research Triangle Institute International · 2015 - 2017UPenn - NEI Follow-up Study: Comparison of AMD Treatment Trials (CATT) YR3
ResearchCo Investigator · Awarded by University of Pennsylvania · 2013 - 2017Using Optical Coherence Tomography to Elucidate Optic Nerve Development in Healthy Infants and Children
ResearchCollaborator · Awarded by Knights Templar Eye Foundation, Inc. · 2015 - 2017Field Deployable Optical Coherence Tomography for Triage of Ocular Trauma
ResearchCo Investigator · Awarded by United States Army Medical Research and Materiel Command · 2012 - 2016Smartphone ophthalmoscope image analysis of lens capsule vascularity to estimate preterm gestational age
ResearchPrincipal Investigator · Awarded by Research Triangle Institute · 2014 - 2016Novel Retinal Biomarkers for Early Detection of Alzheimer's Disease
ResearchCo Investigator · Awarded by Alzheimer's Association · 2013 - 2016Coherent light scattering for early detection of retinal disease
ResearchCo Investigator · Awarded by National Institutes of Health · 2013 - 2016Coordinating Center for the Comparison of AMD Treatments Trials
ResearchCo Investigator · Awarded by University of Pennsylvania · 2014 - 2015Portable Motion Compensated SDOCT System for Imaging Young Children
ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2012 - 2014Real Time Intraoperative SDOCT for Vitreoretinal Surgery
ResearchCo Investigator · Awarded by National Institutes of Health · 2009 - 2012External Relationships
- Optical Society of America (Optica)
- Queensland University of Technology
- Roche
- Universities and other research entities. I usually give a few lectures a year and they have a small amount of speaker honoraria
- University of California
- University of Michigan-Shanghai Jiao Tong University Joint Institute
This faculty member (or a member of their immediate family) has reported outside activities with the companies, institutions, or organizations listed above. This information is available to institutional leadership and, when appropriate, management plans are in place to address potential conflicts of interest.