Novel aminoalkyl tris-cyclometalated iridium complexes as cellular stains.
Publication
, Journal Article
Sansee, A; Meksawangwong, S; Chainok, K; Franz, KJ; Gál, M; Pålsson, L-O; Puniyan, W; Traiphol, R; Pal, R; Kielar, F
Published in: Dalton transactions (Cambridge, England : 2003)
November 2016
Herein we report the synthesis and investigation of the properties of two tris-cyclometalated luminescent iridium complexes. These complexes are the simple derivatives of fac-[Ir(ppy)3] bearing amino alkyl groups on one of the phenylpyridine rings. The complexes are highly emissive and exhibit structured emission peaks in aqueous solution while having only broad unstructured emission in organic solvents. The complexes have been shown to be taken up by NIH-3T3 and PC3 cells, where they localize in the lysosomes and remain emissive with lifetimes in the microsecond domain.
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Published In
Dalton transactions (Cambridge, England : 2003)
DOI
EISSN
1477-9234
ISSN
1477-9226
Publication Date
November 2016
Volume
45
Issue
43
Start / End Page
17420 / 17430
Related Subject Headings
- Organometallic Compounds
- NIH 3T3 Cells
- Molecular Structure
- Mice
- Lysosomes
- Luminescent Agents
- Luminescence
- Iridium
- Inorganic & Nuclear Chemistry
- Humans
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Sansee, A., Meksawangwong, S., Chainok, K., Franz, K. J., Gál, M., Pålsson, L.-O., … Kielar, F. (2016). Novel aminoalkyl tris-cyclometalated iridium complexes as cellular stains. Dalton Transactions (Cambridge, England : 2003), 45(43), 17420–17430. https://doi.org/10.1039/c6dt02776h
Sansee, A., S. Meksawangwong, K. Chainok, K. J. Franz, M. Gál, L. -. O. Pålsson, W. Puniyan, R. Traiphol, R. Pal, and F. Kielar. “Novel aminoalkyl tris-cyclometalated iridium complexes as cellular stains.” Dalton Transactions (Cambridge, England : 2003) 45, no. 43 (November 2016): 17420–30. https://doi.org/10.1039/c6dt02776h.
Sansee A, Meksawangwong S, Chainok K, Franz KJ, Gál M, Pålsson L-O, et al. Novel aminoalkyl tris-cyclometalated iridium complexes as cellular stains. Dalton transactions (Cambridge, England : 2003). 2016 Nov;45(43):17420–30.
Sansee, A., et al. “Novel aminoalkyl tris-cyclometalated iridium complexes as cellular stains.” Dalton Transactions (Cambridge, England : 2003), vol. 45, no. 43, Nov. 2016, pp. 17420–30. Epmc, doi:10.1039/c6dt02776h.
Sansee A, Meksawangwong S, Chainok K, Franz KJ, Gál M, Pålsson L-O, Puniyan W, Traiphol R, Pal R, Kielar F. Novel aminoalkyl tris-cyclometalated iridium complexes as cellular stains. Dalton transactions (Cambridge, England : 2003). 2016 Nov;45(43):17420–17430.
Published In
Dalton transactions (Cambridge, England : 2003)
DOI
EISSN
1477-9234
ISSN
1477-9226
Publication Date
November 2016
Volume
45
Issue
43
Start / End Page
17420 / 17430
Related Subject Headings
- Organometallic Compounds
- NIH 3T3 Cells
- Molecular Structure
- Mice
- Lysosomes
- Luminescent Agents
- Luminescence
- Iridium
- Inorganic & Nuclear Chemistry
- Humans