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Adult age differences in frontostriatal representation of prediction error but not reward outcome.

Publication ,  Journal Article
Samanez-Larkin, GR; Worthy, DA; Mata, R; McClure, SM; Knutson, B
Published in: Cognitive, affective & behavioral neuroscience
June 2014

Emerging evidence from decision neuroscience suggests that although younger and older adults show similar frontostriatal representations of reward magnitude, older adults often show deficits in feedback-driven reinforcement learning. In the present study, healthy adults completed reward-based tasks that did or did not depend on probabilistic learning, while undergoing functional neuroimaging. We observed reductions in the frontostriatal representation of prediction errors during probabilistic learning in older adults. In contrast, we found evidence for stability across adulthood in the representation of reward outcome in a task that did not require learning. Together, the results identify changes across adulthood in the dynamic coding of relational representations of feedback, in spite of preserved reward sensitivity in old age. Overall, the results suggest that the neural representation of prediction error, but not reward outcome, is reduced in old age. These findings reveal a potential dissociation between cognition and motivation with age and identify a potential mechanism for explaining changes in learning-dependent decision making in old adulthood.

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Published In

Cognitive, affective & behavioral neuroscience

DOI

EISSN

1531-135X

ISSN

1530-7026

Publication Date

June 2014

Volume

14

Issue

2

Start / End Page

672 / 682

Related Subject Headings

  • Time Factors
  • Reward
  • Predictive Value of Tests
  • Oxygen
  • Neural Pathways
  • Motivation
  • Middle Aged
  • Male
  • Magnetic Resonance Imaging
  • Learning
 

Citation

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Samanez-Larkin, G. R., Worthy, D. A., Mata, R., McClure, S. M., & Knutson, B. (2014). Adult age differences in frontostriatal representation of prediction error but not reward outcome. Cognitive, Affective & Behavioral Neuroscience, 14(2), 672–682. https://doi.org/10.3758/s13415-014-0297-4
Samanez-Larkin, Gregory R., Darrell A. Worthy, Rui Mata, Samuel M. McClure, and Brian Knutson. “Adult age differences in frontostriatal representation of prediction error but not reward outcome.Cognitive, Affective & Behavioral Neuroscience 14, no. 2 (June 2014): 672–82. https://doi.org/10.3758/s13415-014-0297-4.
Samanez-Larkin GR, Worthy DA, Mata R, McClure SM, Knutson B. Adult age differences in frontostriatal representation of prediction error but not reward outcome. Cognitive, affective & behavioral neuroscience. 2014 Jun;14(2):672–82.
Samanez-Larkin, Gregory R., et al. “Adult age differences in frontostriatal representation of prediction error but not reward outcome.Cognitive, Affective & Behavioral Neuroscience, vol. 14, no. 2, June 2014, pp. 672–82. Epmc, doi:10.3758/s13415-014-0297-4.
Samanez-Larkin GR, Worthy DA, Mata R, McClure SM, Knutson B. Adult age differences in frontostriatal representation of prediction error but not reward outcome. Cognitive, affective & behavioral neuroscience. 2014 Jun;14(2):672–682.
Journal cover image

Published In

Cognitive, affective & behavioral neuroscience

DOI

EISSN

1531-135X

ISSN

1530-7026

Publication Date

June 2014

Volume

14

Issue

2

Start / End Page

672 / 682

Related Subject Headings

  • Time Factors
  • Reward
  • Predictive Value of Tests
  • Oxygen
  • Neural Pathways
  • Motivation
  • Middle Aged
  • Male
  • Magnetic Resonance Imaging
  • Learning