Skip to main content

Third generation anthropomorphic physical phantom for mammography and DBT: Incorporating voxelized 3D printing and uniform chest wall QC region

Publication ,  Conference
Zhao, C; Solomon, J; Sturgeon, GM; Gehm, ME; Catenacci, M; Wiley, BJ; Samei, E; Lo, JY
Published in: Progress in Biomedical Optics and Imaging - Proceedings of SPIE
January 1, 2017

Physical breast phantoms provide a standard method to test, optimize, and develop clinical mammography systems, including new digital breast tomosynthesis (DBT) systems. In previous work, we produced an anthropomorphic phantom based on 500x500x500 μm breast CT data using commercial 3D printing. We now introduce an improved phantom based on a new cohort of virtual models with 155x155x155 μm voxels and fabricated through voxelized 3D printing and dithering, which confer higher resolution and greater control over contrast. This new generation includes a uniform chest wall extension for evaluating conventional QC metrics. The uniform region contains a grayscale step wedge, chest wall coverage markers, fiducial markers, spheres, and metal ink stickers of line pairs and edges to assess contrast, resolution, artifact spread function, MTF, and other criteria. We also experimented with doping photopolymer material with calcium, iodine, and zinc to increase our current contrast. In particular, zinc was discovered to significantly increase attenuation beyond 100% breast density with a linear relationship between zinc concentration and attenuation or breast density. This linear relationship was retained when the zinc-doped material was applied in conjunction with 3D printing. As we move towards our long term goal of phantoms that are indistinguishable from patients, this new generation of anthropomorphic physical breast phantom validates our voxelized printing process, demonstrates the utility of a uniform QC region with features from 3D printing and metal ink stickers, and shows potential for improved contrast via doping.

Duke Scholars

Published In

Progress in Biomedical Optics and Imaging - Proceedings of SPIE

DOI

ISSN

1605-7422

ISBN

9781510607095

Publication Date

January 1, 2017

Volume

10132
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Zhao, C., Solomon, J., Sturgeon, G. M., Gehm, M. E., Catenacci, M., Wiley, B. J., … Lo, J. Y. (2017). Third generation anthropomorphic physical phantom for mammography and DBT: Incorporating voxelized 3D printing and uniform chest wall QC region. In Progress in Biomedical Optics and Imaging - Proceedings of SPIE (Vol. 10132). https://doi.org/10.1117/12.2256091
Zhao, C., J. Solomon, G. M. Sturgeon, M. E. Gehm, M. Catenacci, B. J. Wiley, E. Samei, and J. Y. Lo. “Third generation anthropomorphic physical phantom for mammography and DBT: Incorporating voxelized 3D printing and uniform chest wall QC region.” In Progress in Biomedical Optics and Imaging - Proceedings of SPIE, Vol. 10132, 2017. https://doi.org/10.1117/12.2256091.
Zhao C, Solomon J, Sturgeon GM, Gehm ME, Catenacci M, Wiley BJ, et al. Third generation anthropomorphic physical phantom for mammography and DBT: Incorporating voxelized 3D printing and uniform chest wall QC region. In: Progress in Biomedical Optics and Imaging - Proceedings of SPIE. 2017.
Zhao, C., et al. “Third generation anthropomorphic physical phantom for mammography and DBT: Incorporating voxelized 3D printing and uniform chest wall QC region.” Progress in Biomedical Optics and Imaging - Proceedings of SPIE, vol. 10132, 2017. Scopus, doi:10.1117/12.2256091.
Zhao C, Solomon J, Sturgeon GM, Gehm ME, Catenacci M, Wiley BJ, Samei E, Lo JY. Third generation anthropomorphic physical phantom for mammography and DBT: Incorporating voxelized 3D printing and uniform chest wall QC region. Progress in Biomedical Optics and Imaging - Proceedings of SPIE. 2017.

Published In

Progress in Biomedical Optics and Imaging - Proceedings of SPIE

DOI

ISSN

1605-7422

ISBN

9781510607095

Publication Date

January 1, 2017

Volume

10132