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Organ dose variability and trends in tomosynthesis and radiography.

Publication ,  Journal Article
Hoye, J; Zhang, Y; Agasthya, G; Sturgeon, G; Kapadia, A; Segars, WP; Samei, E
Published in: J Med Imaging (Bellingham)
July 2017

The purpose of this study was to investigate relationships between patient attributes and organ dose for a population of computational phantoms for 20 tomosynthesis and radiography protocols. Organ dose was estimated from 54 adult computational phantoms (age: 18 to 78 years, weight 52 to 117 kg) using a validated Monte-Carlo simulation (PENELOPE) of a system capable of performing tomosynthesis and radiography. The geometry and field of view for each exam were modeled to match clinical protocols. For each protocol, the energy deposited in each organ was estimated by the simulations, converted to dose units, and then normalized by exposure in air. Dose to radiosensitive organs was studied as a function of average patient thickness in the region of interest and as a function of body mass index. For tomosynthesis, organ doses were also studied as a function of x-ray tube position. This work developed comprehensive information for organ dose dependencies across a range of tomosynthesis and radiography protocols. The results showed a protocol-dependent exponential decrease with an increasing patient size. There was a variability in organ dose across the patient population, which should be incorporated in the metrology of organ dose. The results can be used to prospectively and retrospectively estimate organ dose for tomosynthesis and radiography.

Duke Scholars

Published In

J Med Imaging (Bellingham)

DOI

ISSN

2329-4302

Publication Date

July 2017

Volume

4

Issue

3

Start / End Page

031207

Location

United States

Related Subject Headings

  • 4003 Biomedical engineering
  • 3202 Clinical sciences
 

Citation

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ICMJE
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Hoye, J., Zhang, Y., Agasthya, G., Sturgeon, G., Kapadia, A., Segars, W. P., & Samei, E. (2017). Organ dose variability and trends in tomosynthesis and radiography. J Med Imaging (Bellingham), 4(3), 031207. https://doi.org/10.1117/1.JMI.4.3.031207
Hoye, Jocelyn, Yakun Zhang, Greeshma Agasthya, Greg Sturgeon, Anuj Kapadia, W Paul Segars, and Ehsan Samei. “Organ dose variability and trends in tomosynthesis and radiography.J Med Imaging (Bellingham) 4, no. 3 (July 2017): 031207. https://doi.org/10.1117/1.JMI.4.3.031207.
Hoye J, Zhang Y, Agasthya G, Sturgeon G, Kapadia A, Segars WP, et al. Organ dose variability and trends in tomosynthesis and radiography. J Med Imaging (Bellingham). 2017 Jul;4(3):031207.
Hoye, Jocelyn, et al. “Organ dose variability and trends in tomosynthesis and radiography.J Med Imaging (Bellingham), vol. 4, no. 3, July 2017, p. 031207. Pubmed, doi:10.1117/1.JMI.4.3.031207.
Hoye J, Zhang Y, Agasthya G, Sturgeon G, Kapadia A, Segars WP, Samei E. Organ dose variability and trends in tomosynthesis and radiography. J Med Imaging (Bellingham). 2017 Jul;4(3):031207.

Published In

J Med Imaging (Bellingham)

DOI

ISSN

2329-4302

Publication Date

July 2017

Volume

4

Issue

3

Start / End Page

031207

Location

United States

Related Subject Headings

  • 4003 Biomedical engineering
  • 3202 Clinical sciences