William Paul Segars
Associate Professor in Radiology
Our current research involves the use of computer-generated phantoms and simulation techniques to investigate and optimize medical imaging systems and methods. Medical imaging simulation involves virtual experiments carried out entirely on the computer using computational models for the patients as well as the imaging devices. Simulation is a powerful tool for characterizing, evaluating, and optimizing medical imaging systems. A vital aspect of simulation is to have realistic models of the subject's anatomy as well as accurate models for the physics of the imaging process. Without this, the results of the simulation may not be indicative of what would occur in actual clinical studies and would, therefore, have limited practical value. We are leading the development of realistic simulation tools for use toward human and small animal imaging research.
These tools have a wide variety of applications in many different imaging modalities to investigate the effects of anatomical, physiological, physical, and instrumentational factors on medical imaging and to research new image acquisition strategies, image processing and reconstruction methods, and image visualization and interpretation techniques. We are currently applying them to the field of x-ray CT. The motivation for this work is the lack of sufficiently rigorous methods for optimizing the image quality and radiation dose in x-ray CT to the clinical needs of a given procedure. The danger of unnecessary radiation exposure from CT applications, especially for pediatrics, is just now being addressed. Optimization is essential in order for new and emerging CT applications to be truly useful and not represent a danger to the patient. Given the relatively high radiation doses required of current CT systems, thorough optimization is unlikely to ever be done in live patients. It would be prohibitively expensive to fabricate physical phantoms to simulate a realistic range of patient sizes and clinical needs especially when physiologic motion needs to be considered. The only practical approach to the optimization problem is through the use of realistic computer simulation tools developed in our work.
These tools have a wide variety of applications in many different imaging modalities to investigate the effects of anatomical, physiological, physical, and instrumentational factors on medical imaging and to research new image acquisition strategies, image processing and reconstruction methods, and image visualization and interpretation techniques. We are currently applying them to the field of x-ray CT. The motivation for this work is the lack of sufficiently rigorous methods for optimizing the image quality and radiation dose in x-ray CT to the clinical needs of a given procedure. The danger of unnecessary radiation exposure from CT applications, especially for pediatrics, is just now being addressed. Optimization is essential in order for new and emerging CT applications to be truly useful and not represent a danger to the patient. Given the relatively high radiation doses required of current CT systems, thorough optimization is unlikely to ever be done in live patients. It would be prohibitively expensive to fabricate physical phantoms to simulate a realistic range of patient sizes and clinical needs especially when physiologic motion needs to be considered. The only practical approach to the optimization problem is through the use of realistic computer simulation tools developed in our work.
Current Appointments & Affiliations
- Associate Professor in Radiology, Radiology, Clinical Science Departments 2018
Contact Information
- Box 2731 Med Ctr, 2424 Erwin Road, Durham, NC 27710
- Hock Plaza Suite 302, 2424 Erwin Road, Durham, NC 27705
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paul.segars@duke.edu
(919) 684-1473
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Google Scholar
- Background
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Education, Training, & Certifications
- Ph.D., University of North Carolina - Chapel Hill 2001
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Previous Appointments & Affiliations
- Associate Professor of Biomedical Engineering, Biomedical Engineering, Pratt School of Engineering 2016 - 2018
- Associate Professor in Radiology, Radiology, Clinical Science Departments 2016 - 2018
- Associate Professor of Radiology, Radiology, Clinical Science Departments 2010 - 2016
- Assistant Professor in Radiology, Radiology, Clinical Science Departments 2007 - 2010
- Assistant Professor of Biomedical Engineering, Biomedical Engineering, Pratt School of Engineering 2007 - 2008
- Instructor, Temporary in the Department of Radiology, Radiology, Clinical Science Departments 2006 - 2007
- Recognition
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In the News
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NOV 16, 2022 -
SEP 7, 2022 Pratt School of Engineering
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Awards & Honors
- Expertise
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Subject Headings
- Adult
- Anatomy
- Animals
- Biomechanical Phenomena
- Breast
- Child
- Computer Simulation
- Error
- Finite Element Analysis
- Humans
- Infant
- Models, Anatomic
- Models, Animal
- Models, Biological
- Models, Cardiovascular
- Motion
- Pediatrics
- Phantoms, Imaging
- Positron-Emission Tomography
- Respiratory Mechanics
- Software
- Tomography, Emission-Computed
- Tomography, X-Ray Computed
- Tomosynthesis
- Uncertainty
- Research
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Selected Grants
- Accuracy and Precision in CT Quantification of COPD Through Virtual Imaging Trials awarded by National Institutes of Health 2021 - 2026
- Simulation Tools for 3D and 4D CT and Dosimetry awarded by National Institutes of Health 2007 - 2024
- Toward precision radiotherapy: Physiological modeling of respiratory motion based on ultra-quality 4D-MRI awarded by University of Virginia - Charlottesville 2019 - 2023
- eXtended Modular ANthropomorphic (XMAN) phantom for Imaging and Treatment Optimization in Radiotherapy awarded by University of Maryland, Baltimore 2022 - 2023
- Precision Cardiac CT: Development of a Computational Platform for Optimizing Imaging awarded by National Institutes of Health 2017 - 2023
- Open-access X-ray and CT simulation toolkit for research in cancer imaging and dosimetry awarded by GE Global Research 2019 - 2021
- Training in Medical Imaging awarded by National Institutes of Health 2003 - 2020
- Assessing deformable image registration in the lung using hyperpolarized-gas MRI awarded by National Institutes of Health 2016 - 2018
- 3D Digital Breast Phantoms For Multimodality Research awarded by National Institutes of Health 2010 - 2014
- Multi-Scale Model of the Human Heart for Imaging Research awarded by National Institutes of Health 2009 - 2013
- Cross-disciplinary Training in Medical Physics awarded by National Institutes of Health 2007 - 2013
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External Relationships
- Gammex (Sun Nuclear)
- METIS Health Analytics, LLC
- Publications & Artistic Works
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Selected Publications
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Academic Articles
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Abadi, Ehsan, Giavanna Jadick, David A. Lynch, W Paul Segars, and Ehsan Samei. “Emphysema Quantifications With CT Scan: Assessing the Effects of Acquisition Protocols and Imaging Parameters Using Virtual Imaging Trials.” Chest 163, no. 5 (May 2023): 1084–1100. https://doi.org/10.1016/j.chest.2022.11.033.Full Text Link to Item
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Ho, Fong Chi, Saman Sotoudeh-Paima, W Paul Segars, Ehsan Samei, and Ehsan Abadi. “Development and Application of a Virtual Imaging Trial framework for Airway Quantifications via CT.” Proc Spie Int Soc Opt Eng 12463 (February 2023). https://doi.org/10.1117/12.2654263.Full Text Link to Item
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McCabe, Cindy, Thomas J. Sauer, Mojtaba Zarei, W Paul Segars, Ehsan Samei, and Ehsan Abadi. “A systematic assessment of photon-counting CT for bone mineral density and microarchitecture quantifications.” Proc Spie Int Soc Opt Eng 12463 (February 2023).Link to Item
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Häggmark, Ilian, Kian Shaker, Sven Nyrén, Bariq Al-Amiry, Ehsan Abadi, William P Segars, Ehsan Samei, and Hans M Hertz. “Phase-contrast virtual chest radiography.” Proc Natl Acad Sci U S A 120, no. 1 (January 3, 2023): e2210214120. https://doi.org/10.1073/pnas.2210214120.Full Text Link to Item
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Chen, Junyu, Eric C. Frey, Yufan He, William P. Segars, Ye Li, and Yong Du. “TransMorph: Transformer for unsupervised medical image registration.” Med Image Anal 82 (November 2022): 102615. https://doi.org/10.1016/j.media.2022.102615.Full Text Link to Item
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Fedrigo, Roberto, William P. Segars, Patrick Martineau, Claire Gowdy, Ingrid Bloise, Carlos F. Uribe, and Arman Rahmim. “Development of scalable lymphatic system in the 4D XCAT phantom: Application to quantitative evaluation of lymphoma PET segmentations.” Med Phys 49, no. 11 (November 2022): 6871–84. https://doi.org/10.1002/mp.15963.Full Text Link to Item
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Silva, Catherine C. O., Ademir X. da Silva, Delson Braz, Luis F. C. Lima, W. P. Segars, and Lidia V. de Sá. “S-values for radium-223 and absorbed doses estimates for 223RACL2 using three computational phantoms.” Appl Radiat Isot 189 (November 2022): 110387. https://doi.org/10.1016/j.apradiso.2022.110387.Full Text Link to Item
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Wu, Mingye, Paul FitzGerald, Jiayong Zhang, W Paul Segars, Hengyong Yu, Yongshun Xu, and Bruno De Man. “XCIST-an open access x-ray/CT simulation toolkit.” Phys Med Biol 67, no. 19 (September 28, 2022). https://doi.org/10.1088/1361-6560/ac9174.Full Text Link to Item
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Sharma, Shobhit, Anuj Kapadia, Francesco Ria, W Paul Segars, and Ehsan Samei. “Dose coefficients for organ dosimetry in tomosynthesis imaging of adults and pediatrics across diverse protocols.” Med Phys 49, no. 8 (August 2022): 5439–50. https://doi.org/10.1002/mp.15798.Full Text Open Access Copy Link to Item
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Taguchi, Katsuyuki, Christoph Polster, W Paul Segars, Nafi Aygun, and Karl Stierstorfer. “Model-based pulse pileup and charge sharing compensation for photon counting detectors: A simulation study.” Med Phys 49, no. 8 (August 2022): 5038–51. https://doi.org/10.1002/mp.15779.Full Text Link to Item
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Sugiura, Teruyo, Rie Tanaka, Ehsan Samei, William Paul Segars, Ehsan Abadi, Kazuo Kasahara, Noriyuki Ohkura, Masaya Tamura, and Isao Matsumoto. “Quantitative analysis of changes in lung density by dynamic chest radiography in association with CT values: a virtual imaging study and initial clinical corroboration.” Radiol Phys Technol 15, no. 1 (March 2022): 45–53. https://doi.org/10.1007/s12194-021-00648-w.Full Text Link to Item
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Sharma, Shobhit, Anuj Kapadia, Justin Brown, William Paul Segars, Wesley Bolch, and Ehsan Samei. “A GPU-accelerated framework for individualized estimation of organ doses in digital tomosynthesis.” Med Phys 49, no. 2 (February 2022): 891–900. https://doi.org/10.1002/mp.15400.Full Text Link to Item
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Abadi, Ehsan, Cindy McCabe, Brian Harrawood, Saman Sotoudeh-Paima, W Paul Segars, and Ehsan Samei. “Development and Clinical Applications of a Virtual Imaging Framework for Optimizing Photon-counting CT.” Proc Spie Int Soc Opt Eng 12031 (2022). https://doi.org/10.1117/12.2612079.Full Text Link to Item
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Fu, Wanyi, Shobhit Sharma, Ehsan Abadi, Alexandros-Stavros Iliopoulos, Qi Wang, Joseph Y. Lo, Xiaobai Sun, William P. Segars, and Ehsan Samei. “Corrections to "iPhantom: A Framework for Automated Creation of Individualized Computational Phantoms and its Application to CT Organ Dosimetry".” Ieee J Biomed Health Inform 26, no. 1 (January 2022): 478. https://doi.org/10.1109/JBHI.2021.3130397.Full Text Link to Item
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Sotoudeh-Paima, Saman, W Paul Segars, Ehsan Samei, and Ehsan Abadi. “Photon-counting CT versus conventional CT for COPD quantifications: intra-scanner optimization and inter-scanner assessments using virtual imaging trials.” Proc Spie Int Soc Opt Eng 12031 (2022). https://doi.org/10.1117/12.2613003.Full Text Link to Item
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Fricks, Rafael B., Francesco Ria, Hamid Chalian, Pegah Khoshpouri, Ehsan Abadi, Lorenzo Bianchi, William P. Segars, and Ehsan Samei. “Deep learning classification of COVID-19 in chest radiographs: performance and influence of supplemental training.” J Med Imaging (Bellingham) 8, no. 6 (November 2021): 064501. https://doi.org/10.1117/1.JMI.8.6.064501.Full Text Open Access Copy Link to Item
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Ria, Francesco, Wanyi Fu, Jocelyn Hoye, W Paul Segars, Anuj J. Kapadia, and Ehsan Samei. “Correction to: Comparison of 12 surrogates to characterize CT radiation risk across a clinical population.” Eur Radiol 31, no. 10 (October 2021): 8068. https://doi.org/10.1007/s00330-021-07903-z.Full Text Link to Item
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Jadick, Giavanna, Ehsan Abadi, Brian Harrawood, Shobhit Sharma, W Paul Segars, and Ehsan Samei. “A scanner-specific framework for simulating CT images with tube current modulation.” Physics in Medicine and Biology 66, no. 18 (September 2021). https://doi.org/10.1088/1361-6560/ac2269.Full Text
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Ria, Francesco, Wanyi Fu, Jocelyn Hoye, W Paul Segars, Anuj J. Kapadia, and Ehsan Samei. “Comparison of 12 surrogates to characterize CT radiation risk across a clinical population.” Eur Radiol 31, no. 9 (September 2021): 7022–30. https://doi.org/10.1007/s00330-021-07753-9.Full Text Open Access Copy Link to Item
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Bauer, Dominik F., Tom Russ, Barbara I. Waldkirch, Christian Tönnes, William P. Segars, Lothar R. Schad, Frank G. Zöllner, and Alena-Kathrin Golla. “Generation of annotated multimodal ground truth datasets for abdominal medical image registration.” International Journal of Computer Assisted Radiology and Surgery 16, no. 8 (August 2021): 1277–85. https://doi.org/10.1007/s11548-021-02372-7.Full Text
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Fu, Wanyi, Shobhit Sharma, Ehsan Abadi, Alexandros-Stavros Iliopoulos, Qi Wang, Joseph Y. Lo, Xiaobai Sun, William P. Segars, and Ehsan Samei. “iPhantom: A Framework for Automated Creation of Individualized Computational Phantoms and Its Application to CT Organ Dosimetry.” Ieee J Biomed Health Inform 25, no. 8 (August 2021): 3061–72. https://doi.org/10.1109/JBHI.2021.3063080.Full Text Link to Item
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Divel, Sarah E., Soren Christensen, William P. Segars, Maarten G. Lansberg, and Norbert J. Pelc. “A dynamic simulation framework for CT perfusion in stroke assessment built from first principles.” Med Phys 48, no. 7 (July 2021): 3500–3510. https://doi.org/10.1002/mp.14887.Full Text Link to Item
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Gullberg, Grant T., Uttam M. Shrestha, Alexander I. Veress, W Paul Segars, Jing Liu, Karen Ordovas, and Youngho Seo. “Novel Methodology for Measuring Regional Myocardial Efficiency.” Ieee Trans Med Imaging 40, no. 6 (June 2021): 1711–25. https://doi.org/10.1109/TMI.2021.3065219.Full Text Link to Item
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Chang, Yushi, Zhuoran Jiang, William Paul Segars, Zeyu Zhang, Kyle Lafata, Jing Cai, Fang-Fang Yin, and Lei Ren. “A generative adversarial network (GAN)-based technique for synthesizing realistic respiratory motion in the extended cardiac-torso (XCAT) phantoms.” Phys Med Biol 66, no. 11 (May 31, 2021). https://doi.org/10.1088/1361-6560/ac01b4.Full Text Link to Item
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Tanaka, Rie, Ehsan Samei, William Paul Segars, Ehsan Abadi, Isao Matsumoto, Masaya Tamura, Munehisa Takata, and Tsuneo Yamashiro. “Assessment of pleural invasion and adhesion of lung tumors with dynamic chest radiography: A virtual clinical imaging study.” Med Phys 48, no. 4 (April 2021): 1616–23. https://doi.org/10.1002/mp.14750.Full Text Link to Item
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Sharma, Shobhit, Ehsan Abadi, Anuj Kapadia, W Paul Segars, and Ehsan Samei. “A GPU-accelerated framework for rapid estimation of scanner-specific scatter in CT for virtual imaging trials.” Phys Med Biol 66, no. 7 (March 23, 2021). https://doi.org/10.1088/1361-6560/abeb32.Full Text Link to Item
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Fu, Wanyi, Francesco Ria, William Paul Segars, Kingshuk Roy Choudhury, Joshua M. Wilson, Anuj J. Kapadia, and Ehsan Samei. “Patient-Informed Organ Dose Estimation in Clinical CT: Implementation and Effective Dose Assessment in 1048 Clinical Patients.” Ajr Am J Roentgenol 216, no. 3 (March 2021): 824–34. https://doi.org/10.2214/AJR.19.22482.Full Text Open Access Copy Link to Item
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Abadi, Ehsan, W. Paul Segars, Hamid Chalian, and Ehsan Samei. “Virtual Imaging Trials for Coronavirus Disease (COVID-19).” Ajr Am J Roentgenol 216, no. 2 (February 2021): 362–68. https://doi.org/10.2214/AJR.20.23429.Full Text Link to Item
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Samei, Ehsan, Taylor Richards, William P. Segars, Melissa A. Daubert, Alex Ivanov, Geoffrey D. Rubin, Pamela S. Douglas, and Udo Hoffmann. “Task-dependent estimability index to assess the quality of cardiac computed tomography angiography for quantifying coronary stenosis.” J Med Imaging (Bellingham) 8, no. 1 (January 2021): 013501. https://doi.org/10.1117/1.JMI.8.1.013501.Full Text Link to Item
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Taguchi, Katsuyuki, Thomas J. Sauer, W Paul Segars, Eric C. Frey, Jingyan Xu, Eleni Liapi, J Webster Stayman, et al. “Three-dimensional regions-of-interest-based intra-operative four-dimensional soft tissue perfusion imaging using a standard x-ray system with no gantry rotation: A simulation study for a proof of concept.” Med Phys 47, no. 12 (December 2020): 6087–6102. https://doi.org/10.1002/mp.14514.Full Text Link to Item
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MacDonald, Lawrence R., Joseph Y. Lo, Gregory M. Sturgeon, Chengeng Zeng, Robert L. Harrison, Paul E. Kinahan, and William Paul Segars. “Impact of Using Uniform Attenuation Coefficients for Heterogeneously Dense Breasts in a Dedicated Breast PET/X-ray Scanner.” Ieee Trans Radiat Plasma Med Sci 4, no. 5 (September 2020): 585–93. https://doi.org/10.1109/trpms.2020.2991120.Full Text Link to Item
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Abadi, Ehsan, William P. Segars, Benjamin M. W. Tsui, Paul E. Kinahan, Nick Bottenus, Alejandro F. Frangi, Andrew Maidment, Joseph Lo, and Ehsan Samei. “Virtual clinical trials in medical imaging: a review.” J Med Imaging (Bellingham) 7, no. 4 (July 2020): 042805. https://doi.org/10.1117/1.JMI.7.4.042805.Full Text Link to Item
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Abadi, Ehsan, William P. Segars, Brian Harrawood, Shobhit Sharma, Anuj Kapadia, and Ehsan Samei. “Virtual clinical trial for quantifying the effects of beam collimation and pitch on image quality in computed tomography.” J Med Imaging (Bellingham) 7, no. 4 (July 2020): 042806. https://doi.org/10.1117/1.JMI.7.4.042806.Full Text Link to Item
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Chang, Yushi, Kyle Lafata, William Paul Segars, Fang-Fang Yin, and Lei Ren. “Development of realistic multi-contrast textured XCAT (MT-XCAT) phantoms using a dual-discriminator conditional-generative adversarial network (D-CGAN).” Phys Med Biol 65, no. 6 (March 19, 2020): 065009. https://doi.org/10.1088/1361-6560/ab7309.Full Text Link to Item
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Sharma, Shobhit, Anuj Kapadia, Wanyi Fu, Ehsan Abadi, W Paul Segars, and Ehsan Samei. “A real-time Monte Carlo tool for individualized dose estimations in clinical CT.” Phys Med Biol 64, no. 21 (November 4, 2019): 215020. https://doi.org/10.1088/1361-6560/ab467f.Full Text Link to Item
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Hoye, Jocelyn, Shobhit Sharma, Yakun Zhang, Wanyi Fu, Francesco Ria, Anuj Kapadia, W Paul Segars, Joshua Wilson, and Ehsan Samei. “Organ doses from CT localizer radiographs: Development, validation, and application of a Monte Carlo estimation technique.” Med Phys 46, no. 11 (November 2019): 5262–72. https://doi.org/10.1002/mp.13781.Full Text Open Access Copy Link to Item
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Hoye, Jocelyn, Shobhit Sharma, Yakun Zhang, Wanyi Fu, Francesco Ria, Anuj Kapadia, W Paul Segars, Joshua Wilson, and Ehsan Samei. “Organ doses from CT localizer radiographs: Development, validation, and application of a Monte Carlo estimation technique.” Medical Physics 46, no. 11 (November 1, 2019): 5262–72. https://doi.org/10.1002/mp.13781].Full Text Open Access Copy Link to Item
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Abadi, Ehsan, Brian Harrawood, Jayasai R. Rajagopal, Shobhit Sharma, Anuj Kapadia, William Paul Segars, Karl Stierstorfer, Martin Sedlmair, Elizabeth Jones, and Ehsan Samei. “Development of a scanner-specific simulation framework for photon-counting computed tomography.” Biomed Phys Eng Express 5, no. 5 (August 2019). https://doi.org/10.1088/2057-1976/ab37e9.Full Text Link to Item
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Gullberg, Grant T., Alexander I. Veress, Uttam M. Shrestha, Jing Liu, Karen Ordovas, W Paul Segars, and Youngho Seo. “Multiresolution spatiotemporal mechanical model of the heart as a prior to constrain the solution for 4D models of the heart.” Proc Spie Int Soc Opt Eng 11072 (June 2019). https://doi.org/10.1117/12.2534906.Full Text Link to Item
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Abadi, Ehsan, Brian Harrawood, Shobhit Sharma, Anuj Kapadia, William P. Segars, and Ehsan Samei. “DukeSim: A Realistic, Rapid, and Scanner-Specific Simulation Framework in Computed Tomography.” Ieee Trans Med Imaging 38, no. 6 (June 2019): 1457–65. https://doi.org/10.1109/TMI.2018.2886530.Full Text Link to Item
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Roy, Christopher W., Davide Marini, William Paul Segars, Mike Seed, and Christopher K. Macgowan. “Fetal XCMR: a numerical phantom for fetal cardiovascular magnetic resonance imaging.” J Cardiovasc Magn Reson 21, no. 1 (May 23, 2019): 29. https://doi.org/10.1186/s12968-019-0539-2.Full Text Link to Item
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Segars, W Paul, Alexander I. Veress, Gregory M. Sturgeon, and Ehsan Samei. “Incorporation of the Living Heart Model into the 4D XCAT Phantom for Cardiac Imaging Research.” Ieee Trans Radiat Plasma Med Sci 3, no. 1 (January 2019): 54–60. https://doi.org/10.1109/TRPMS.2018.2823060.Full Text Link to Item
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Abadi, Ehsan, William P. Segars, Gregory M. Sturgeon, Brian Harrawood, Anuj Kapadia, and Ehsan Samei. “Modeling "Textured" Bones in Virtual Human Phantoms.” Ieee Trans Radiat Plasma Med Sci 3, no. 1 (January 2019): 47–53. https://doi.org/10.1109/TRPMS.2018.2828083.Full Text Link to Item
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Abadi, Ehsan, William P. Segars, Gregory M. Sturgeon, Justus E. Roos, Carl E. Ravin, and Ehsan Samei. “Modeling Lung Architecture in the XCAT Series of Phantoms: Physiologically Based Airways, Arteries and Veins.” Ieee Trans Med Imaging 37, no. 3 (March 2018): 693–702. https://doi.org/10.1109/TMI.2017.2769640.Full Text Link to Item
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Segars, W Paul, B. M. W. Tsui, B. M. W. Jing Cai, B. M. W. Fang-Fang Yin, George S. K. Fung, and Ehsan Samei. “Application of the 4-D XCAT Phantoms in Biomedical Imaging and Beyond.” Ieee Trans Med Imaging 37, no. 3 (March 2018): 680–92. https://doi.org/10.1109/TMI.2017.2738448.Full Text Link to Item
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Richards, Taylor, Gregory M. Sturgeon, Juan Carlos Ramirez-Giraldo, Geoffrey D. Rubin, Lynne Hurwitz Koweek, William Paul Segars, and Ehsan Samei. “Quantification of uncertainty in the assessment of coronary plaque in CCTA through a dynamic cardiac phantom and 3D-printed plaque model.” J Med Imaging (Bellingham) 5, no. 1 (January 2018): 013501. https://doi.org/10.1117/1.JMI.5.1.013501.Full Text Link to Item
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Wang, Chunhao, Fang-Fang Yin, W. P. Segars, Zheng Chang, and Lei Ren. “Development of a Computerized 4-D MRI Phantom for Liver Motion Study.” Technol Cancer Res Treat 16, no. 6 (December 2017): 1051–59. https://doi.org/10.1177/1533034617723753.Full Text Link to Item
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Samei, Ehsan, Xiaoyu Tian, W. Paul Segars, and Donald P. Frush. “Radiation risk index for pediatric CT: a patient-derived metric.” Pediatr Radiol 47, no. 13 (December 2017): 1737–44. https://doi.org/10.1007/s00247-017-3973-z.Full Text Link to Item
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Sturgeon, Gregory M., Subok Park, William Paul Segars, and Joseph Y. Lo. “Synthetic breast phantoms from patient based eigenbreasts.” Med Phys 44, no. 12 (December 2017): 6270–79. https://doi.org/10.1002/mp.12579.Full Text Link to Item
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Fu, Wanyi, Gregory M. Sturgeon, Greeshma Agasthya, William Paul Segars, Anuj J. Kapadia, and Ehsan Samei. “Breast dose reduction with organ-based, wide-angle tube current modulated CT.” J Med Imaging (Bellingham) 4, no. 3 (July 2017): 031208. https://doi.org/10.1117/1.JMI.4.3.031208.Full Text Link to Item
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Hoye, Jocelyn, Yakun Zhang, Greeshma Agasthya, Greg Sturgeon, Anuj Kapadia, W Paul Segars, and Ehsan Samei. “Organ dose variability and trends in tomosynthesis and radiography.” J Med Imaging (Bellingham) 4, no. 3 (July 2017): 031207. https://doi.org/10.1117/1.JMI.4.3.031207.Full Text Link to Item
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Tang, Jing, Xinhui Wang, Xiangzhen Gao, W Paul Segars, Martin A. Lodge, and Arman Rahmim. “Enhancing ejection fraction measurement through 4D respiratory motion compensation in cardiac PET imaging.” Phys Med Biol 62, no. 11 (June 7, 2017): 4496–4513. https://doi.org/10.1088/1361-6560/aa6417.Full Text Link to Item
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Sahbaee, Pooyan, Ehsan Abadi, W Paul Segars, Daniele Marin, Rendon C. Nelson, and Ehsan Samei. “The Effect of Contrast Material on Radiation Dose at CT: Part II. A Systematic Evaluation across 58 Patient Models.” Radiology 283, no. 3 (June 2017): 749–57. https://doi.org/10.1148/radiol.2017152852.Full Text Link to Item
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Sahbaee, Pooyan, W Paul Segars, Daniele Marin, Rendon C. Nelson, and Ehsan Samei. “The Effect of Contrast Material on Radiation Dose at CT: Part I. Incorporation of Contrast Material Dynamics in Anthropomorphic Phantoms.” Radiology 283, no. 3 (June 2017): 739–48. https://doi.org/10.1148/radiol.2016152851.Full Text Link to Item
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Carver, Diana E., Susan D. Kost, Nicholas D. Fraser, W Paul Segars, David R. Pickens, Ronald R. Price, and Michael G. Stabin. “Realistic phantoms to characterize dosimetry in pediatric CT.” Pediatr Radiol 47, no. 6 (May 2017): 691–700. https://doi.org/10.1007/s00247-017-3805-1.Full Text Link to Item
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Muryn, John S., Ashraf G. Morgan, Chris L. Liptak, Frank F. Dong, W Paul Segars, Andrew N. Primak, and Xiang Li. “Analysis of uncertainties in Monte Carlo simulated organ and effective dose in chest CT: scanner- and scan-related factors.” Phys Med Biol 62, no. 8 (April 21, 2017): 3175–3203. https://doi.org/10.1088/1361-6560/aa60d7.Full Text Link to Item
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Dasari, Paul K. R., Arda Könik, P Hendrik Pretorius, Karen L. Johnson, William P. Segars, Mohammed S. Shazeeb, and Michael A. King. “Correction of hysteretic respiratory motion in SPECT myocardial perfusion imaging: Simulation and patient studies.” Med Phys 44, no. 2 (February 2017): 437–50. https://doi.org/10.1002/mp.12072.Full Text Link to Item
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Fu, Wanyi, Xiaoyu Tian, Gregory M. Sturgeon, Greeshma Agasthya, William Paul Segars, Mitchell M. Goodsitt, Ella A. Kazerooni, and Ehsan Samei. “CT breast dose reduction with the use of breast positioning and organ-based tube current modulation.” Med Phys 44, no. 2 (February 2017): 665–78. https://doi.org/10.1002/mp.12076.Full Text Link to Item
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Sanders, Jeremiah, Xiaoyu Tian, William Paul Segars, John Boone, and Ehsan Samei. “Automated, patient-specific estimation of regional imparted energy and dose from tube current modulated computed tomography exams across 13 protocols.” J Med Imaging (Bellingham) 4, no. 1 (January 2017): 013503. https://doi.org/10.1117/1.JMI.4.1.013503.Full Text Link to Item
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Kiarashi, Nooshin, Loren W. Nolte, Joseph Y. Lo, W Paul Segars, Sujata V. Ghate, Justin B. Solomon, and Ehsan Samei. “Impact of breast structure on lesion detection in breast tomosynthesis, a simulation study.” J Med Imaging (Bellingham) 3, no. 3 (July 2016): 035504. https://doi.org/10.1117/1.JMI.3.3.035504.Full Text Link to Item
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Tian, Xiaoyu, W Paul Segars, Robert L. Dixon, and Ehsan Samei. “Convolution-based estimation of organ dose in tube current modulated CT.” Phys Med Biol 61, no. 10 (May 21, 2016): 3935–54. https://doi.org/10.1088/0031-9155/61/10/3935.Full Text Link to Item
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Sturgeon, Gregory M., Nooshin Kiarashi, Joseph Y. Lo, E. Samei, and W. P. Segars. “Finite-element modeling of compression and gravity on a population of breast phantoms for multimodality imaging simulation.” Med Phys 43, no. 5 (May 2016): 2207. https://doi.org/10.1118/1.4945275.Full Text Link to Item
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Krishnamurthy, Adarsh, Matthew J. Gonzales, Gregory Sturgeon, W Paul Segars, and Andrew D. McCulloch. “Biomechanics Simulations Using Cubic Hermite Meshes with Extraordinary Nodes for Isogeometric Cardiac Modeling.” Comput Aided Geom Des 43 (March 2016): 27–38. https://doi.org/10.1016/j.cagd.2016.02.016.Full Text Link to Item
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Smyczynski, Mark S., Howard C. Gifford, Andre Lehovich, Joseph E. McNamara, W Paul Segars, Eric A. Hoffman, Benjamin M. W. Tsui, and Michael A. King. “Modeling the respiratory motion of solitary pulmonary nodules and determining the impact of respiratory motion on their detection in SPECT imaging.” Ieee Trans Nucl Sci 63, no. 1 (February 2016): 117–29. https://doi.org/10.1109/TNS.2015.2512840.Full Text Link to Item
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Smyczynski, Mark S., Howard C. Gifford, Joyoni Dey, Andre Lehovich, Joseph E. McNamara, W Paul Segars, and Michael A. King. “LROC Investigation of Three Strategies for Reducing the Impact of Respiratory Motion on the Detection of Solitary Pulmonary Nodules in SPECT.” Ieee Trans Nucl Sci 63, no. 1 (February 2016): 130–39. https://doi.org/10.1109/TNS.2015.2481825.Full Text Link to Item
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Erickson, David W., Jered R. Wells, Gregory M. Sturgeon, Ehsan Samei, James T. Dobbins, W Paul Segars, and Joseph Y. Lo. “Population of 224 realistic human subject-based computational breast phantoms.” Med Phys 43, no. 1 (January 2016): 23. https://doi.org/10.1118/1.4937597.Full Text Link to Item
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Li, Xiang, Ashraf G. Morgan, Christopher L. Liptak, John S. Muryn, Frank F. Dong, Andrew N. Primak, and W Paul Segars. “Adult abdomen-pelvis CT: Does equilibrium dose-pitch product better account for the kVp dependence of organ dose than conventional CTDI?” Med Phys 42, no. 11 (November 2015): 6258–68. https://doi.org/10.1118/1.4932222.Full Text Link to Item
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Stabin, Michael G., Susan D. Kost, William P. Segars, and Raymond A. Guilmette. “Two Realistic Beagle Models for Dose Assessment.” Health Phys 109, no. 3 (September 2015): 198–204. https://doi.org/10.1097/HP.0000000000000324.Full Text Link to Item
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Segars, W. P., Hannah Norris, Gregory M. Sturgeon, Yakun Zhang, Jason Bond, Anum Minhas, Daniel J. Tward, et al. “The development of a population of 4D pediatric XCAT phantoms for imaging research and optimization.” Med Phys 42, no. 8 (August 2015): 4719–26. https://doi.org/10.1118/1.4926847.Full Text Link to Item
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Dey, Joyoni, W Paul Segars, P Hendrik Pretorius, and Michael A. King. “Effect of Non-Alignment/Alignment of Attenuation Map Without/With Emission Motion Correction in Cardiac SPECT/CT.” Ieee Trans Nucl Sci 62, no. 4 (August 2015): 1813–24. https://doi.org/10.1109/TNS.2015.2446895.Full Text Link to Item
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Sung, Yongjin, W Paul Segars, Adam Pan, Masami Ando, Colin J. R. Sheppard, and Rajiv Gupta. “Realistic wave-optics simulation of X-ray phase-contrast imaging at a human scale.” Sci Rep 5 (July 14, 2015): 12011. https://doi.org/10.1038/srep12011.Full Text Link to Item
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Kiarashi, Nooshin, Adam C. Nolte, Gregory M. Sturgeon, William P. Segars, Sujata V. Ghate, Loren W. Nolte, Ehsan Samei, and Joseph Y. Lo. “Development of realistic physical breast phantoms matched to virtual breast phantoms based on human subject data.” Med Phys 42, no. 7 (July 2015): 4116–26. https://doi.org/10.1118/1.4919771.Full Text Link to Item
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Veress, Alexander I., George S. K. Fung, Taek-Soo Lee, Benjamin M. W. Tsui, Gregory A. Kicska, W. Paul Segars, and Grant T. Gullberg. “The direct incorporation of perfusion defect information to define ischemia and infarction in a finite element model of the left ventricle.” J Biomech Eng 137, no. 5 (May 2015): 051004. https://doi.org/10.1115/1.4028989.Full Text Link to Item
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Tian, Xiaoyu, Xiang Li, W Paul Segars, Donald P. Frush, and Ehsan Samei. “Prospective estimation of organ dose in CT under tube current modulation.” Med Phys 42, no. 4 (April 2015): 1575–85. https://doi.org/10.1118/1.4907955.Full Text Link to Item
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Segars, W. P., K. Rybicki, Hannah Norris, D. Frush, and E. Samei. “Organ localization: toward prospective patient-specific organ dosimetry in computed tomography.” Med Phys 41, no. 12 (December 2014): 121908. https://doi.org/10.1118/1.4901554.Full Text Link to Item
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Tremblay, Marilyn, Gary H. Kramer, Kevin Capello, and Paul Segars. “Effect of respiratory motion on lung counting efficiency using a 4D NURBS-based cardio-torso (NCAT) phantom.” Health Phys 107, no. 6 (December 2014): 564–69. https://doi.org/10.1097/HP.0000000000000156.Full Text Link to Item
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Samei, Ehsan, Xiaoyu Tian, and W Paul Segars. “Determining organ dose: the holy grail.” Pediatr Radiol 44 Suppl 3 (October 2014): 460–67. https://doi.org/10.1007/s00247-014-3117-7.Full Text Link to Item
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Sechopoulos, Ioannis, John M. Sabol, Johan Berglund, Wesley E. Bolch, Libby Brateman, Emmanuel Christodoulou, Michael Flynn, et al. “Radiation dosimetry in digital breast tomosynthesis: report of AAPM Tomosynthesis Subcommittee Task Group 223.” Med Phys 41, no. 9 (September 2014): 091501. https://doi.org/10.1118/1.4892600.Full Text Link to Item
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Li, Xiang, W Paul Segars, and Ehsan Samei. “The impact on CT dose of the variability in tube current modulation technology: a theoretical investigation.” Phys Med Biol 59, no. 16 (August 21, 2014): 4525–48. https://doi.org/10.1088/0031-9155/59/16/4525.Full Text Link to Item
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Wissmann, Lukas, Claudio Santelli, William P. Segars, and Sebastian Kozerke. “MRXCAT: Realistic numerical phantoms for cardiovascular magnetic resonance.” J Cardiovasc Magn Reson 16, no. 1 (August 20, 2014): 63. https://doi.org/10.1186/s12968-014-0063-3.Full Text Link to Item
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Könik, Arda, Caitlin M. Connolly, Karen L. Johnson, Paul Dasari, Paul W. Segars, P. H. Pretorius, Clifford Lindsay, Joyoni Dey, and Michael A. King. “Digital anthropomorphic phantoms of non-rigid human respiratory and voluntary body motion for investigating motion correction in emission imaging.” Phys Med Biol 59, no. 14 (July 21, 2014): 3669–82. https://doi.org/10.1088/0031-9155/59/14/3669.Full Text Link to Item
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Kiarashi, Nooshin, Joseph Y. Lo, Yuan Lin, Lynda C. Ikejimba, Sujata V. Ghate, Loren W. Nolte, James T. Dobbins, William P. Segars, and Ehsan Samei. “Development and application of a suite of 4-D virtual breast phantoms for optimization and evaluation of breast imaging systems.” Ieee Trans Med Imaging 33, no. 7 (July 2014): 1401–9. https://doi.org/10.1109/TMI.2014.2312733.Full Text Link to Item
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Sahbaee, Pooyan, W Paul Segars, and Ehsan Samei. “Patient-based estimation of organ dose for a population of 58 adult patients across 13 protocol categories.” Med Phys 41, no. 7 (July 2014): 072104. https://doi.org/10.1118/1.4883778.Full Text Link to Item
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Belley, Matthew D., William Paul Segars, and Anuj J. Kapadia. “Assessment of individual organ doses in a realistic human phantom from neutron and gamma stimulated spectroscopy of the breast and liver.” Med Phys 41, no. 6 (June 2014): 063902. https://doi.org/10.1118/1.4873684.Full Text Link to Item
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Norris, Hannah, Yakun Zhang, Jason Bond, Gregory M. Sturgeon, Anum Minhas, Daniel J. Tward, J. T. Ratnanather, et al. “A set of 4D pediatric XCAT reference phantoms for multimodality research.” Med Phys 41, no. 3 (March 2014): 033701. https://doi.org/10.1118/1.4864238.Full Text Link to Item
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Tian, Xiaoyu, Xiang Li, W Paul Segars, Erik K. Paulson, Donald P. Frush, and Ehsan Samei. “Pediatric chest and abdominopelvic CT: organ dose estimation based on 42 patient models.” Radiology 270, no. 2 (February 2014): 535–47. https://doi.org/10.1148/radiol.13122617.Full Text Link to Item
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Zhang, Yakun, Xiang Li, W Paul Segars, and Ehsan Samei. “Comparison of patient specific dose metrics between chest radiography, tomosynthesis, and CT for adult patients of wide ranging body habitus.” Med Phys 41, no. 2 (February 2014): 023901. https://doi.org/10.1118/1.4859315.Full Text Link to Item
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Dobbins, J. T., J. R. Wells, and W. P. Segars. “Dose reduction in CT with correlated-polarity noise reduction: Context-dependent spatial resolution and noise properties demonstrating two-fold dose reduction with minimal artifacts.” Progress in Biomedical Optics and Imaging Proceedings of Spie 9033 (January 1, 2014). https://doi.org/10.1117/12.2043685.Full Text
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Norris, H., Y. Zhang, J. Frush, G. M. Sturgeon, A. Minhas, D. J. Tward, J. T. Ratnanather, et al. “The development of a population of 4D pediatric XCAT phantoms for CT imaging research and optimization.” Progress in Biomedical Optics and Imaging Proceedings of Spie 9033 (January 1, 2014). https://doi.org/10.1117/12.2043777.Full Text
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Tian, X., X. Li, W. P. Segars, D. Frush, and E. Samei. “Prospective optimization of CT under Tube current modulation: I. organ dose.” Progress in Biomedical Optics and Imaging Proceedings of Spie 9033 (January 1, 2014). https://doi.org/10.1117/12.2043858.Full Text
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Tian, Xiaoyu, Xiang Li, W Paul Segars, Donald P. Frush, Erik K. Paulson, and Ehsan Samei. “Dose coefficients in pediatric and adult abdominopelvic CT based on 100 patient models.” Phys Med Biol 58, no. 24 (December 21, 2013): 8755–68. https://doi.org/10.1088/0031-9155/58/24/8755.Full Text Link to Item
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Zhang, You, Fang-Fang Yin, W Paul Segars, and Lei Ren. “A technique for estimating 4D-CBCT using prior knowledge and limited-angle projections.” Med Phys 40, no. 12 (December 2013): 121701. https://doi.org/10.1118/1.4825097.Full Text Link to Item
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Vergalasova, I., J. Cai, W. Giles, W. P. Segars, and F. F. Yin. “Evaluation of the effect of respiratory and anatomical variables on a Fourier technique for markerless, self-sorted 4D-CBCT.” Phys Med Biol 58, no. 20 (October 21, 2013): 7239–59. https://doi.org/10.1088/0031-9155/58/20/7239.Full Text Link to Item
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Gonzales, Matthew J., Gregory Sturgeon, Adarsh Krishnamurthy, Johan Hake, René Jonas, Paul Stark, Wouter-Jan Rappel, et al. “A three-dimensional finite element model of human atrial anatomy: new methods for cubic Hermite meshes with extraordinary vertices.” Med Image Anal 17, no. 5 (July 2013): 525–37. https://doi.org/10.1016/j.media.2013.03.005.Full Text Link to Item
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Cheng, Lishui, Robert F. Hobbs, Paul W. Segars, George Sgouros, and Eric C. Frey. “Improved dose-volume histogram estimates for radiopharmaceutical therapy by optimizing quantitative SPECT reconstruction parameters.” Phys Med Biol 58, no. 11 (June 7, 2013): 3631–47. https://doi.org/10.1088/0031-9155/58/11/3631.Full Text Link to Item
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Li, X., W. P. Segars, and E. Samei. “Organ dose in chest CT: Effect of modulation scheme on estimation accuracy.” Progress in Biomedical Optics and Imaging Proceedings of Spie 8668 (June 3, 2013). https://doi.org/10.1117/12.2008505.Full Text
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Zhang, Y., X. Li, W. Paul Segars, and E. Samei. “Comparative dosimetry of radiography, tomosynthesis, and CT for chest imaging across 59 adult patients.” Progress in Biomedical Optics and Imaging Proceedings of Spie 8668 (June 3, 2013). https://doi.org/10.1117/12.2008544.Full Text
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Hsu, Christina M. L., Mark L. Palmeri, W Paul Segars, Alexander I. Veress, and James T. Dobbins. “Generation of a suite of 3D computer-generated breast phantoms from a limited set of human subject data.” Med Phys 40, no. 4 (April 2013): 043703. https://doi.org/10.1118/1.4794924.Full Text Link to Item
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Segars, W. P., Jason Bond, Jack Frush, Sylvia Hon, Chris Eckersley, Cameron H. Williams, Jianqiao Feng, et al. “Population of anatomically variable 4D XCAT adult phantoms for imaging research and optimization.” Med Phys 40, no. 4 (April 2013): 043701. https://doi.org/10.1118/1.4794178.Full Text Link to Item
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Genc, K., P. Segars, S. Cockram, D. Thompson, M. Horner, R. Cotton, and P. Young. “Workflow for creating a simulation ready virtual population for finite element modeling.” Asme 2013 Conference on Frontiers in Medical Devices: Applications of Computer Modeling and Simulation, Fmd 2013, January 1, 2013. https://doi.org/10.1115/FMD2013-16027.Full Text
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III, J. T. D., J. R. Wells, and W. P. Segars. “Dose reduction in CT with correlated-polarity noise reduction: Comparable image quality at half the dose with projection space processing.” Progress in Biomedical Optics and Imaging Proceedings of Spie 8668 (2013). https://doi.org/10.1117/12.2008563.Full Text
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Dey, J., A. Konik, W. P. Segars, and M. A. King. “Multi-modal rigid and non-rigid registration for attenuation correction in cardiac SPECT/CT using emission scatter to CT conversion.” Ieee Nuclear Science Symposium Conference Record, December 1, 2012, 2859–66. https://doi.org/10.1109/NSSMIC.2012.6551653.Full Text
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Li, Xiang, Ehsan Samei, Cameron H. Williams, W Paul Segars, Daniel J. Tward, Michael I. Miller, J Tilak Ratnanather, Erik K. Paulson, and Donald P. Frush. “Effects of protocol and obesity on dose conversion factors in adult body CT.” Med Phys 39, no. 11 (November 2012): 6550–71. https://doi.org/10.1118/1.4754584.Full Text Link to Item
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Stabin, Michael G., X George Xu, Mary A. Emmons, W Paul Segars, Chengyu Shi, and Michael J. Fernald. “RADAR reference adult, pediatric, and pregnant female phantom series for internal and external dosimetry.” J Nucl Med 53, no. 11 (November 2012): 1807–13. https://doi.org/10.2967/jnumed.112.106138.Full Text Link to Item
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Mishra, Pankaj, Sara St James, W Paul Segars, Ross I. Berbeco, and John H. Lewis. “Adaptation and applications of a realistic digital phantom based on patient lung tumor trajectories.” Phys Med Biol 57, no. 11 (June 7, 2012): 3597–3608. https://doi.org/10.1088/0031-9155/57/11/3597.Full Text Link to Item
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Zhang, Yakun, Xiang Li, W Paul Segars, and Ehsan Samei. “Organ doses, effective doses, and risk indices in adult CT: comparison of four types of reference phantoms across different examination protocols.” Med Phys 39, no. 6 (June 2012): 3404–23. https://doi.org/10.1118/1.4718710.Full Text Link to Item
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Panta, R., W. Segars, F. Yin, and J. Cai. “SU-E-J-145: Implementing 4D XCAT Phantom for 4D Radiotherapy Research.” Med Phys 39, no. 6Part8 (June 2012): 3686. https://doi.org/10.1118/1.4734981.Full Text Link to Item
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Qin, Y., Z. Chang, W. Segars, F. Yin, and J. Cai. “SU-D-218-02: 4D-MRI Based on Body Area (BA) Surrogate and Sagittal Image Acquisition.” Med Phys 39, no. 6Part3 (June 2012): 3622. https://doi.org/10.1118/1.4734705.Full Text Link to Item
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Zhang, F., Y. Qin, W. Segars, F. Yin, and J. Cai. “MO-A-213AB-04: Verification of 4D Dose Delivery Using 4D Digital Human Phantom.” Med Phys 39, no. 6Part20 (June 2012): 3859. https://doi.org/10.1118/1.4735756.Full Text Link to Item
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Lindsay, C., M. A. Gennert, C. M. Connolly, A. Konik, P. K. Dasari, W. P. Segars, and M. A. King. “Interactive generation of digital anthropomorphic phantoms from XCAT shape priors.” Progress in Biomedical Optics and Imaging Proceedings of Spie 8317 (May 14, 2012). https://doi.org/10.1117/12.911275.Full Text
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Bond, J., J. Frush, S. Hon, C. Eckersley, C. H. Williams, J. Feng, D. J. Tward, et al. “Series of 4D adult XCAT phantoms for imaging research and dosimetry.” Progress in Biomedical Optics and Imaging Proceedings of Spie 8313 (May 4, 2012). https://doi.org/10.1117/12.911676.Full Text
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Tian, X., X. Li, W. P. Segars, D. P. Frush, and E. Samei. “Patient- and cohort-specific dose and risk estimation for abdominopelvic CT: A study based on 100 patients.” Progress in Biomedical Optics and Imaging Proceedings of Spie 8313 (May 4, 2012). https://doi.org/10.1117/12.913341.Full Text
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Stabin, M. G., M. A. Emmons, W. P. Segars, and M. J. Fernald. “Realistic reference adult and paediatric phantom series for internal and external dosimetry.” Radiat Prot Dosimetry 149, no. 1 (March 2012): 56–59. https://doi.org/10.1093/rpd/ncr383.Full Text Link to Item
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Panta, Raj K., Paul Segars, Fang-Fang Yin, and Jing Cai. “Establishing a framework to implement 4D XCAT phantom for 4D radiotherapy research.” J Cancer Res Ther 8, no. 4 (2012): 565–70. https://doi.org/10.4103/0973-1482.106539.Full Text Link to Item
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Cai, Jing, Zheng Chang, Zhiheng Wang, William Paul Segars, and Fang-Fang Yin. “Four-dimensional magnetic resonance imaging (4D-MRI) using image-based respiratory surrogate: a feasibility study.” Med Phys 38, no. 12 (December 2011): 6384–94. https://doi.org/10.1118/1.3658737.Full Text Link to Item
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Veress, A. I., G. S. K. Fung, B. M. W. Tsui, W. P. Segars, and G. T. Gullberg. “Incorporation of perfusion information into a finite element model of the left ventricle.” Asme 2011 Summer Bioengineering Conference, Sbc 2011, no. PARTS A AND B (December 1, 2011): 151–52. https://doi.org/10.1115/SBC2011-53285.Full Text
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Hsu, Christina M. L., Mark L. Palmeri, W Paul Segars, Alexander I. Veress, and James T. Dobbins. “An analysis of the mechanical parameters used for finite element compression of a high-resolution 3D breast phantom.” Med Phys 38, no. 10 (October 2011): 5756–70. https://doi.org/10.1118/1.3637500.Full Text Link to Item
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Fung, George S. K., Takahiro Higuchi, Min Jae Park, W Paul Segars, and Benjamin M. W. Tsui. “Development of a 4D Digital Phantom for Tracer Kinetic Modeling and Analysis of Dynamic Perfusion PET and SPECT Simulation Studies.” Ieee Nucl Sci Symp Conf Rec (1997) 2011 (October 2011): 4192–95. https://doi.org/10.1109/NSSMIC.2011.6153803.Full Text Link to Item
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Fung, George S. K., W Paul Segars, Grant T. Gullberg, and Benjamin M. W. Tsui. “Development of a model of the coronary arterial tree for the 4D XCAT phantom.” Phys Med Biol 56, no. 17 (September 7, 2011): 5651–63. https://doi.org/10.1088/0031-9155/56/17/012.Full Text Link to Item
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Tward, D. J., C. Ceritoglu, G. Sturgeon, W. P. Segars, M. I. Miller, and J. T. Ratnanather. “Generating patient-specific dosimetry phantoms with whole-body diffeomorphic image registration.” 2011 Ieee 37th Annual Northeast Bioengineering Conference, Nebec 2011, June 16, 2011. https://doi.org/10.1109/NEBC.2011.5778717.Full Text
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Li, Xiang, Ehsan Samei, W Paul Segars, Gregory M. Sturgeon, James G. Colsher, and Donald P. Frush. “Patient-specific radiation dose and cancer risk for pediatric chest CT.” Radiology 259, no. 3 (June 2011): 862–74. https://doi.org/10.1148/radiol.11101900.Full Text Link to Item
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Tang, Jing, W Paul Segars, Taek-Soo Lee, Xin He, Arman Rahmim, and Benjamin M. W. Tsui. “Quantitative study of cardiac motion estimation and abnormality classification in emission computed tomography.” Med Eng Phys 33, no. 5 (June 2011): 563–72. https://doi.org/10.1016/j.medengphy.2010.12.006.Full Text Link to Item
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Connolly, C. M., A. Konik, P. K. R. Dasari, P. Segars, S. Zheng, K. L. Johnson, J. Dey, and M. A. King. “Creation of 3D digital anthropomorphic phantoms which model actual patient non-rigid body motion as determined from MRI and position tracking studies of volunteers.” Progress in Biomedical Optics and Imaging Proceedings of Spie 7964 (May 16, 2011). https://doi.org/10.1117/12.878193.Full Text
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Fung, G. S. K., K. Stierstorfer, W. P. Segars, K. Taguchi, T. G. Flohr, and B. M. W. Tsui. “XCAT/DRASIM: A realistic CT/human-model simulation package.” Progress in Biomedical Optics and Imaging Proceedings of Spie 7961 (May 13, 2011). https://doi.org/10.1117/12.878034.Full Text
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Li, X., E. Samei, W. P. Segars, E. K. Paulson, and D. P. Frush. “The feasibility of universal DLP-to-risk conversion coefficients for body CT protocols.” Progress in Biomedical Optics and Imaging Proceedings of Spie 7961 (May 13, 2011). https://doi.org/10.1117/12.878616.Full Text
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Wells, J. R., W. P. Segars, C. J. N. Kigongo, and J. T. Dobbins. “Refinement of motion correction strategies for lower-cost CT for under-resourced regions of the world.” Progress in Biomedical Optics and Imaging Proceedings of Spie 7961 (May 13, 2011). https://doi.org/10.1117/12.878697.Full Text
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Veress, Alexander I., W Paul Segars, Benjamin M. W. Tsui, and Grant T. Gullberg. “Incorporation of a left ventricle finite element model defining infarction into the XCAT imaging phantom.” Ieee Trans Med Imaging 30, no. 4 (April 2011): 915–27. https://doi.org/10.1109/TMI.2010.2089801.Full Text Link to Item
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Dey, J., W. P. Segars, P. H. Pretorius, and M. A. King. “Investigation of respiratory motion correction with and without motion correction of attenuation map in cardiac SPECT/CT in presence of non-rigid motion, an NCAT study.” Ieee Nuclear Science Symposium Conference Record, January 1, 2011, 3237–43. https://doi.org/10.1109/NSSMIC.2011.6152580.Full Text
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Karakatsanis, N. A., M. A. Lodge, Y. Zhou, J. Mhlanga, M. A. Chaudhry, A. K. Tahari, W. P. Segars, R. L. Wahl, and A. Rahmim. “Dynamic multi-bed FDG PET imaging: Feasibility and optimization.” Ieee Nuclear Science Symposium Conference Record, January 1, 2011, 3863–70. https://doi.org/10.1109/NSSMIC.2011.6153735.Full Text
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Könik, A., C. M. Connolly, K. L. Johnson, P. Dasari, P. Segars, P. H. Pretorius, and M. A. King. “Digital anthropomorphic phantoms of non-rigid human respiratory and voluntary body motions: A tool-set for investigating motion correction in 3D reconstruction.” Ieee Nuclear Science Symposium Conference Record, January 1, 2011, 3572–78. https://doi.org/10.1109/NSSMIC.2011.6153671.Full Text
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Li, Xiang, Ehsan Samei, W Paul Segars, Gregory M. Sturgeon, James G. Colsher, Greta Toncheva, Terry T. Yoshizumi, and Donald P. Frush. “Patient-specific radiation dose and cancer risk estimation in CT: part II. Application to patients.” Med Phys 38, no. 1 (January 2011): 408–19. https://doi.org/10.1118/1.3515864.Full Text Link to Item
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Li, Xiang, Ehsan Samei, W Paul Segars, Gregory M. Sturgeon, James G. Colsher, Greta Toncheva, Terry T. Yoshizumi, and Donald P. Frush. “Patient-specific radiation dose and cancer risk estimation in CT: part I. development and validation of a Monte Carlo program.” Med Phys 38, no. 1 (January 2011): 397–407. https://doi.org/10.1118/1.3515839.Full Text Link to Item
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Tward, Daniel J., Can Ceritoglu, Anthony Kolasny, Gregory M. Sturgeon, W Paul Segars, Michael I. Miller, and J Tilak Ratnanather. “Patient Specific Dosimetry Phantoms Using Multichannel LDDMM of the Whole Body.” Int J Biomed Imaging 2011 (2011): 481064. https://doi.org/10.1155/2011/481064.Full Text Link to Item
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Cheung, A. A., T. Niu, T. L. Faber, W. P. Segars, L. Zhu, and J. Chen. “Simulation of left ventricular dyssynchrony using the XCAT phantom.” Ieee Nuclear Science Symposium Conference Record, December 1, 2010, 3187–89. https://doi.org/10.1109/NSSMIC.2010.5874391.Full Text
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Dey, Joyoni, William P. Segars, P Hendrik Pretorius, Ronn P. Walvick, Philippe P. Bruyant, Seth Dahlberg, and Michael A. King. “Estimation and correction of cardiac respiratory motion in SPECT in the presence of limited-angle effects due to irregular respiration.” Med Phys 37, no. 12 (December 2010): 6453–65. https://doi.org/10.1118/1.3517836.Full Text Link to Item
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Segars, W. P., G. M. Sturgeon, D. J. Ward, J. T. Ratnanather, M. I. Miller, and B. M. W. Tsui. “The new XCAT series of digital phantoms for multi-modality imaging.” Ieee Nuclear Science Symposium Conference Record, December 1, 2010, 2392–95. https://doi.org/10.1109/NSSMIC.2010.5874215.Full Text
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Segars, W. P., G. Sturgeon, S. Mendonca, Jason Grimes, and B. M. W. Tsui. “4D XCAT phantom for multimodality imaging research.” Med Phys 37, no. 9 (September 2010): 4902–15. https://doi.org/10.1118/1.3480985.Full Text Link to Item
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Tang, Jing, Taek-Soo Lee, Xin He, W Paul Segars, and Benjamin M. W. Tsui. “Comparison of 3D OS-EM and 4D MAP-RBI-EM reconstruction algorithms for cardiac motion abnormality classification using a motion observer.” Ieee Trans Nucl Sci 57, no. 5 (August 26, 2010): 2571. https://doi.org/10.1109/TNS.2010.2050604.Full Text Link to Item
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Lewis, John H., Ruijiang Li, W Tyler Watkins, Joshua D. Lawson, W Paul Segars, Laura I. Cerviño, William Y. Song, and Steve B. Jiang. “Markerless lung tumor tracking and trajectory reconstruction using rotational cone-beam projections: a feasibility study.” Phys Med Biol 55, no. 9 (May 7, 2010): 2505–22. https://doi.org/10.1088/0031-9155/55/9/006.Full Text Link to Item
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McGurk, Ross, Joao Seco, Marco Riboldi, John Wolfgang, Paul Segars, and Harald Paganetti. “Extension of the NCAT phantom for the investigation of intra-fraction respiratory motion in IMRT using 4D Monte Carlo.” Phys Med Biol 55, no. 5 (March 7, 2010): 1475–90. https://doi.org/10.1088/0031-9155/55/5/014.Full Text Link to Item
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Keenan, Mary A., Michael G. Stabin, William P. Segars, and Michael J. Fernald. “RADAR realistic animal model series for dose assessment.” J Nucl Med 51, no. 3 (March 2010): 471–76. https://doi.org/10.2967/jnumed.109.070532.Full Text Link to Item
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Fung, George S. K., W Paul Segars, Taek-Soo Lee, Takahiro Higuchi, Alexander I. Veress, Grant T. Gullberg, and Benjamin M. W. Tsui. “Realistic Simulation of Regional Myocardial Perfusion Defects for Cardiac SPECT Studies.” Ieee Nucl Sci Symp Conf Rec (1997) 2010 (2010): 3061–64. https://doi.org/10.1109/NSSMIC.2010.5874362.Full Text Link to Item
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Tabary, J., S. Marache-Francisco, S. Valette, W. P. Segars, and C. Lartizien. “Realistic X-ray CT simulation of the XCAT phantom with SINDBAD.” Ieee Nuclear Science Symposium Conference Record, December 1, 2009, 3980–83. https://doi.org/10.1109/NSSMIC.2009.5401942.Full Text
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Xi, H., B. W. Schafer, W. P. Segars, F. Eckstein, V. Kuhn, T. J. Beck, and T. Lee. “Assessing the Susceptibility to Local Buckling at the Femoral Neck Cortex to Age-Related Bone Loss.” Ifmbe Proceedings 23 (December 1, 2009): 1918–19. https://doi.org/10.1007/978-3-540-92841-6_476.Full Text
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Paul Segars, W., and Benjamin M. W. Tsui. “MCAT to XCAT: The Evolution of 4-D Computerized Phantoms for Imaging Research: Computer models that take account of body movements promise to provide evaluation and improvement of medical imaging devices and technology.” Proc Ieee Inst Electr Electron Eng 97, no. 12 (December 2009): 1954–68. https://doi.org/10.1109/JPROC.2009.2022417.Full Text Link to Item
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Minarik, D., M. Ljungberg, P. Segars, and K Sjögreen Gleisner. “Evaluation of quantitative planar 90Y bremsstrahlung whole-body imaging.” Phys Med Biol 54, no. 19 (October 7, 2009): 5873–83. https://doi.org/10.1088/0031-9155/54/19/014.Full Text Link to Item
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Segars, W Paul, David S. Lalush, Eric C. Frey, Dinesh Manocha, Michael A. King, and Benjamin M. W. Tsui. “Improved Dynamic Cardiac Phantom Based on 4D NURBS and Tagged MRI.” Ieee Trans Nucl Sci 56, no. 5 (October 1, 2009): 2728–38. https://doi.org/10.1109/TNS.2009.2016196.Full Text Link to Item
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Lee, Taeyong, Jae Bong Choi, Benjamin W. Schafer, W Paul Segars, Felix Eckstein, Volker Kuhn, and Thomas J. Beck. “Assessing the susceptibility to local buckling at the femoral neck cortex to age-related bone loss.” Ann Biomed Eng 37, no. 9 (September 2009): 1910–20. https://doi.org/10.1007/s10439-009-9751-9.Full Text Link to Item
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Li, Christina M., W Paul Segars, Georgia D. Tourassi, John M. Boone, and James T. Dobbins. “Methodology for generating a 3D computerized breast phantom from empirical data.” Med Phys 36, no. 7 (July 2009): 3122–31. https://doi.org/10.1118/1.3140588.Full Text Link to Item
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Fung, G. S. K., W. P. Segars, A. I. Veress, G. T. Gullberg, and B. M. W. Tsui. “Toward modeling of regional myocardial ischemia and infarction: Generation of realistic coronary arterial tree for the heart model of the XCAT phantom.” Progress in Biomedical Optics and Imaging Proceedings of Spie 7262 (June 22, 2009). https://doi.org/10.1117/12.811571.Full Text
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Segars, W. P., G. Sturgeon, X. Li, L. Cheng, C. Ceritoglu, J. T. Ratnanather, M. I. Miller, B. M. W. Tsui, D. Frush, and E. Samei. “Patient specific computerized phantoms to estimate dose in pediatric CT.” Progress in Biomedical Optics and Imaging Proceedings of Spie 7258 (June 16, 2009). https://doi.org/10.1117/12.813517.Full Text
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Li, X., E. Samei, W. P. Segars, G. M. Sturgeon, J. G. Colsher, and D. P. Frush. “Patient-specific dose estimation for pediatric abdomen-pelvisCT.” Progress in Biomedical Optics and Imaging Proceedings of Spie 7258 (June 15, 2009). https://doi.org/10.1117/12.813531.Full Text
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He, Bin, Yong Du, W Paul Segars, Richard L. Wahl, George Sgouros, Heather Jacene, and Eric C. Frey. “Evaluation of quantitative imaging methods for organ activity and residence time estimation using a population of phantoms having realistic variations in anatomy and uptake.” Med Phys 36, no. 2 (February 2009): 612–19. https://doi.org/10.1118/1.3063156.Full Text Link to Item
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Segars, W. P., Seng Peng Mok, and Benjamin M. W. Tsui. “Investigation of Respiratory Gating in Quantitative Myocardial SPECT.” Ieee Trans Nucl Sci 56, no. 1 (February 1, 2009): 91–96. https://doi.org/10.1109/TNS.2008.2007739.Full Text Link to Item
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Le Maitre, A., W. P. Segars, S. Marache, A. Reilhac, M. Hatt, S. Tomei, C. Lartizien, and D. Visvikis. “Incorporating patient-specific variability in the simulation of realistic whole-body 18F-FDG distributions for oncology applications.” Proceedings of the Ieee 97, no. 12 (January 1, 2009): 2026–38. https://doi.org/10.1109/JPROC.2009.2027925.Full Text
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Dey, J., W. P. Segars, P. H. Pretorius, and M. A. King. “Estimation and correction of irregular respiratory motion of the heart in presence of partial angle effects due to amplitude binning in SPECT.” Ieee Nuclear Science Symposium Conference Record, December 1, 2008, 3656–62. https://doi.org/10.1109/NSSMIC.2008.4774110.Full Text
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Li, Xiang, Ehsan Samei, W Paul Segars, Gregory M. Sturgeon, James G. Colsher, and Donald P. Frush. “Patient-specific dose estimation for pediatric chest CT.” Med Phys 35, no. 12 (December 2008): 5821–28. https://doi.org/10.1118/1.3026593.Full Text Link to Item
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Smyczynski, M. S., H. C. Gifford, A. Lehovich, J. E. Mcnamara, W. P. Segars, J. Dey, and M. A. King. “Effectiveness of three alternative strategies in reducing the degrading impact ofrespiratory motion on the detection of small pulmonary nodules in SPECT imaging.” Ieee Nuclear Science Symposium Conference Record, December 1, 2008, 3663–67. https://doi.org/10.1109/NSSMIC.2008.4774111.Full Text
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Sun, Z., W. P. Segars, E. K. Fishman, J. A. Brinker, and K. Taguchi. “Banding artifact reduction for cardiac CT.” Ieee Nuclear Science Symposium Conference Record, December 1, 2008, 4838–39. https://doi.org/10.1109/NSSMIC.2008.4774325.Full Text
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Rahmim, Arman, Katie Dinelle, Ju-Chieh Cheng, Mikhail A. Shilov, William P. Segars, Sarah C. Lidstone, Stephan Blinder, et al. “Accurate event-driven motion compensation in high-resolution PET incorporating scattered and random events.” Ieee Trans Med Imaging 27, no. 8 (August 2008): 1018–33. https://doi.org/10.1109/TMI.2008.917248.Full Text Link to Item
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Segars, W. P., M. Mahesh, T. J. Beck, E. C. Frey, and B. M. W. Tsui. “Realistic CT simulation using the 4D XCAT phantom.” Med Phys 35, no. 8 (August 2008): 3800–3808. https://doi.org/10.1118/1.2955743.Full Text Link to Item
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Rahmim, Arman, Ju-Chieh Cheng, Katie Dinelle, Mikhail Shilov, W Paul Segars, Olivier G. Rousset, Benjamin M. W. Tsui, Dean F. Wong, and Vesna Sossi. “System matrix modelling of externally tracked motion.” Nucl Med Commun 29, no. 6 (June 2008): 574–81. https://doi.org/10.1097/MNM.0b013e3282f5d2de.Full Text Link to Item
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Fung, G. S. K., W. P. Segars, J. F. H. Geschwind, B. M. W. Tsui, and K. Taguchi. “Effect of respiratory motion on abdominal C-arm CT angiography using the 4D NCAT phantom.” Ieee Nuclear Science Symposium Conference Record 6 (December 1, 2007): 4536–38. https://doi.org/10.1109/NSSMIC.2007.4437119.Full Text
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Lee, T. S., W. P. Segars, and B. M. W. Tsui. “The development and application of a realistic simulation dataset for simultaneous cardiac and respiratory gated ECT/CT.” Ieee Nuclear Science Symposium Conference Record 5 (December 1, 2007): 3656–59. https://doi.org/10.1109/NSSMIC.2007.4436914.Full Text
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Segars, W. P., S. Mendonca, G. Sturgeon, and B. M. W. Tsui. “Enhanced 4D heart model based on high resolution dual source gated cardiac CT images.” Ieee Nuclear Science Symposium Conference Record 4 (December 1, 2007): 2617–20. https://doi.org/10.1109/NSSMIC.2007.4436684.Full Text
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Segars, W. P., S. Mori, G. T. Y. Chen, and B. M. W. Tsui. “Modeling respiratory motion variations in the 4D NCAT phantom.” Ieee Nuclear Science Symposium Conference Record 4 (December 1, 2007): 2677–79. https://doi.org/10.1109/NSSMIC.2007.4436697.Full Text
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Segars, W. P., S. Mori, G. T. Y. Chen, and B. M. W. Tsui. “Modeling respiratory motion variations in the 4P NCAT phantom.” Ieee Nuclear Science Symposium Conference Record 6 (December 1, 2007): 4531–33. https://doi.org/10.1109/NSSMIC.2007.4437117.Full Text
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Taguchi, K., M. Zhang, E. C. Frey, J. Xu, W. P. Segars, and B. M. W. Tsui. “Image-domain material decomposition using photon-counting CT.” Progress in Biomedical Optics and Imaging Proceedings of Spie 6510, no. PART 1 (October 15, 2007). https://doi.org/10.1117/12.713508.Full Text
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Taguchi, K., S. Zhihui, W. P. Segars, E. K. Fishman, and B. M. W. Tsui. “Image-domain motion compensated time-resolved 4D cardiac CT.” Progress in Biomedical Optics and Imaging Proceedings of Spie 6510, no. PART 1 (October 15, 2007). https://doi.org/10.1117/12.709980.Full Text
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Smyczynski, M. S., H. C. Gifford, A. Lehovich, J. E. McNamara, W. P. Segars, B. M. W. Tsui, and M. A. King. “Impact of respiratory motion on the detection of small pulmonary nodules in SPECT imaging.” Ieee Nucl Sci Symp Conf Rec (1997) 5 (2007): 3241–45. https://doi.org/10.1109/NSSMIC.2007.4436830.Full Text Link to Item
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Veress, Alexander I., W Paul Segars, Jeffrey A. Weiss, Benjamin M. W. Tsui, and Grant T. Gullberg. “Normal and pathological NCAT image and phantom data based on physiologically realistic left ventricle finite-element models.” Ieee Trans Med Imaging 25, no. 12 (December 2006): 1604–16. https://doi.org/10.1109/tmi.2006.884213.Full Text Link to Item
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Kindhan, P., L. MacDonald, L. Ng, A. Alessio, P. Segars, B. Tsui, and S. Pathak. “Compensating for patient respiration in PET/CT imaging with the registered and summed phases (RASP) procedure.” 2006 3rd Ieee International Symposium on Biomedical Imaging: From Nano to Macro Proceedings 2006 (November 17, 2006): 1104–7.
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Fung, G. S. K., W. P. Segars, K. Taguchi, E. K. Fishman, and B. M. W. Tsui. “Development of a computer-generated model for the coronary arterial tree based on multislice CT and morphometric data.” Progress in Biomedical Optics and Imaging Proceedings of Spie 6142 II (June 30, 2006). https://doi.org/10.1117/12.653491.Full Text
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Segars, W. P., K. Taguchi, G. S. K. Fung, E. K. Fishman, and B. M. W. Tsui. “Effect of heart rate on CT angiography using the enhanced cardiac model of the 4D NCAT.” Progress in Biomedical Optics and Imaging Proceedings of Spie 6142 I (June 30, 2006). https://doi.org/10.1117/12.653347.Full Text
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Taguchi, K., W. P. Segars, G. S. K. Fung, and B. M. W. Tsui. “Toward time resolved 4D cardiac CT imaging with patient dose reduction; estimating the global heart motion.” Progress in Biomedical Optics and Imaging Proceedings of Spie 6142 I (June 30, 2006). https://doi.org/10.1117/12.653279.Full Text
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Descourt, P., W. P. Segars, F. Lamare, L. Ferrer, B. Tsui, Y. Bizais, M. Bardiè, and D. Visvikis. “RTNCAT (Real Time NCAT): Implementing Real Time physiological movement of voxellized phantoms in GATE.” Ieee Nuclear Science Symposium Conference Record 5 (January 1, 2006): 3163–65. https://doi.org/10.1109/NSSMIC.2006.356546.Full Text
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Rahmim, A., J. C. Cheng, K. Dinelle, M. Shilov, W. P. Segars, O. G. Rousset, B. M. W. Tsui, D. F. Wong, and V. Sossi. “System matrix modeling of externally tracked motion.” Ieee Nuclear Science Symposium Conference Record 4 (January 1, 2006): 2137–41. https://doi.org/10.1109/NSSMIC.2006.354337.Full Text
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Segars, W. P., S. P. Mok, and B. M. W. Tsui. “Investigation of equal magnitude respiratory gating in quantitative myocardial SPECT.” Ieee Nuclear Science Symposium Conference Record 4 (January 1, 2006): 2107–10. https://doi.org/10.1109/NSSMIC.2006.354330.Full Text
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Shilov, M. A., E. C. Frey, W. P. Segars, J. Xu, and B. M. W. Tsui. “Optimization of gated liver FDG PET with non-uniform respiration.” Ieee Nuclear Science Symposium Conference Record 4 (January 1, 2006): 2594–96. https://doi.org/10.1109/NSSMIC.2006.354438.Full Text
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Taguchi, K., W. P. Segars, H. Kudo, E. C. Frey, E. K. Fishman, and B. M. W. Tsui. “Toward time resolved cardiac CT images with patient dose reduction: Image-based motion estimation.” Ieee Nuclear Science Symposium Conference Record 4 (January 1, 2006): 2029–32. https://doi.org/10.1109/NSSMIC.2006.354312.Full Text
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Tang, J., W. P. Segars, and B. M. W. Tsui. “Cardiac motion estimation from gated emission computed tomography images.” Ieee Nuclear Science Symposium Conference Record 5 (January 1, 2006): 2688–94. https://doi.org/10.1109/NSSMIC.2006.356435.Full Text
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Lee, T. S., W. P. Segars, and B. M. W. Tsui. “Study of parameters characterizing space-time Gibbs priors for 4D MAP-RBI-EM in gated myocardial perfusion SPECT.” Ieee Nuclear Science Symposium Conference Record 4 (December 1, 2005): 2124–28. https://doi.org/10.1109/NSSMIC.2005.1596754.Full Text
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Segars, W. P., and B. M. W. Tsui. “Effect of respiratory motion in CT-based attenuation correction in SPECT using different CT scanners and protocols.” Ieee Nuclear Science Symposium Conference Record 4 (December 1, 2005): 2413–17. https://doi.org/10.1109/NSSMIC.2005.1596819.Full Text
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He, Bin, Yong Du, Xiyun Song, W Paul Segars, and Eric C. Frey. “A Monte Carlo and physical phantom evaluation of quantitative In-111 SPECT.” Phys Med Biol 50, no. 17 (September 7, 2005): 4169–85. https://doi.org/10.1088/0031-9155/50/17/018.Full Text Link to Item
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Kraitchman, Dara L., Mitsuaki Tatsumi, Wesley D. Gilson, Takayoshi Ishimori, Dorota Kedziorek, Piotr Walczak, W Paul Segars, et al. “Dynamic imaging of allogeneic mesenchymal stem cells trafficking to myocardial infarction.” Circulation 112, no. 10 (September 6, 2005): 1451–61. https://doi.org/10.1161/CIRCULATIONAHA.105.537480.Full Text Link to Item
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Segars, W. P., M. Mahesh, T. Beck, E. C. Frey, and B. M. W. Tsui. “Validation of the 4D NCAT simulation tools for use in high-resolution x-ray CT research.” Progress in Biomedical Optics and Imaging Proceedings of Spie 5745, no. II (August 25, 2005): 828–34. https://doi.org/10.1117/12.595987.Full Text
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Song, X., W. P. Segars, Y. Du, B. M. W. Tsui, and E. C. Frey. “Fast modelling of the collimator-detector response in Monte Carlo simulation of SPECT imaging using the angular response function.” Phys Med Biol 50, no. 8 (April 21, 2005): 1791–1804. https://doi.org/10.1088/0031-9155/50/8/011.Full Text Link to Item
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Lalush, David S., Megan K. Jatko, and W Paul Segars. “An observer study methodology for evaluating detection of motion abnormalities in gated myocardial perfusion SPECT.” Ieee Trans Biomed Eng 52, no. 3 (March 2005): 480–85. https://doi.org/10.1109/TBME.2004.843290.Full Text Link to Item
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Guerrero, Thomas, Geoffrey Zhang, William Segars, Tzeng-Chi Huang, Stephen Bilton, Geoffrey Ibbott, Lei Dong, Kenneth Forster, and Kang Ping Lin. “Elastic image mapping for 4-D dose estimation in thoracic radiotherapy.” Radiat Prot Dosimetry 115, no. 1–4 (2005): 497–502. https://doi.org/10.1093/rpd/nci225.Full Text Link to Item
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Mok, S. P., B. M. W. Tsui, Y. Wang, Y. Qi, Y. Du, W. P. Segars, B. C. Yoder, and E. C. Frey. “Development and validation of a Monte Carlo simulation tool for multi-pinhole microSPECT.” Ieee Nuclear Science Symposium Conference Record 6 (December 1, 2004): 3440–44.
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Veress, A. I., W. P. Segars, B. M. W. Tsui, J. A. Weiss, and G. T. Gullberg. “Physiologically realistic LV models to produce normal and pathological image and phantom data.” Ieee Nuclear Science Symposium Conference Record 7 (December 1, 2004): 4231–35.
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He, X., E. C. Frey, J. M. Links, K. L. Gilland, W. P. Segars, and B. M. W. Tsui. “A mathematical observer study for the evaluation and optimization of compensation methods for myocardial SPECT using a phantom population that realistically models patient variability.” Ieee Transactions on Nuclear Science 51, no. 1 I (February 1, 2004): 218–24. https://doi.org/10.1109/TNS.2004.823331.Full Text
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Segars, William P., Benjamin M. W. Tsui, Eric C. Frey, G Allan Johnson, and Stuart S. Berr. “Development of a 4-D digital mouse phantom for molecular imaging research.” Mol Imaging Biol 6, no. 3 (2004): 149–59. https://doi.org/10.1016/j.mibio.2004.03.002.Full Text Link to Item
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Lee, T. S., W. P. Segars, and B. M. W. Tsui. “A study of the effect of cardiac gating in myocardial SPECT using the 4D NCAT.” Ieee Nuclear Science Symposium Conference Record 4 (December 1, 2003): 2681–85.
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Segars, W. P., B. M. W. Tsui, E. C. Frey, and E. K. Fishman. “Extension of the 4D NCAT phantom to dynamic X-ray CT simulation.” Ieee Nuclear Science Symposium Conference Record 5 (December 1, 2003): 3195–99.
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Song, X., E. C. Frey, X. He, W. P. Segars, and B. M. W. Tsui. “A mathematical observer study for evaluation of a model-based compensation method for crosstalk in simultaneous dual isotope SPECT.” Ieee Nuclear Science Symposium Conference Record 4 (December 1, 2003): 2521–25.
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Garrity, J. M., W. Paul Segars, S. B. Knisley, and B. M. W. Tsui. “Development of a Dynamic Model for the Lung Lobes and Airway Tree in the NCAT Phantom.” Ieee Transactions on Nuclear Science 50, no. 3 (January 1, 2003): 378–83. https://doi.org/10.1109/TNS.2003.812445.Full Text
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Garrity, J. M., W. P. Segars, S. Knisley, and B. M. W. Tsui. “Development of a Dynamic Model for the Lung Lobes and Airway Tree in the NCAT Phantom.” Ieee Nuclear Science Symposium and Medical Imaging Conference 3 (December 1, 2002): 1858–62.
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He, X., E. C. Frey, J. Links, K. L. Gilland, W. P. Segars, and B. M. W. Tsui. “Evaluation and Optimization of Compensation Methods for Myocardial SPECT using a Set of Realistic Phantoms that Include Patient Variability.” Ieee Nuclear Science Symposium and Medical Imaging Conference 2 (December 1, 2002): 764–68.
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Segars, W. P., B. M. W. Tsui, A. J. Da Silva, and L. Shao. “CT-PET Image Fusion using the 4D NCAT Phantom with the Purpose of Attenuation Correction.” Ieee Nuclear Science Symposium and Medical Imaging Conference 3 (December 1, 2002): 1775–79.
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Smyczynski, M. S., H. C. Gifford, T. H. Farncombe, W. P. Segars, B. M. W. Tsui, and M. A. King. “Impact of respiratory motion on the detection of solitary pulmonary nodules with SPECT tumor imaging of NeoTect.” Ieee Nuclear Science Symposium and Medical Imaging Conference 2 (December 1, 2002): 838–41.
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Zhu, Z., B. M. W. Tsui, and W. P. Segars. “A Simulation Study of the Effect of Gating Scheme on Respiratory Motion Blurring in FDG Lung PET.” Ieee Nuclear Science Symposium and Medical Imaging Conference 3 (December 1, 2002): 1554–58.
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Segars, W. P., and B. M. W. Tsui. “Study of the efficacy of respiratory gating in myocardial SPECT using the new 4-D NCAT phantom.” Ieee Transactions on Nuclear Science 49 I, no. 3 (June 1, 2002): 675–79. https://doi.org/10.1109/TNS.2002.1039548.Full Text
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Segars, W. P., and B. M. W. Tsui. “Study of the efficacy of respiratory gating in myocardial SPECT using the new 4D NCAT phantom.” Ieee Nuclear Science Symposium and Medical Imaging Conference 3 (December 1, 2001): 1536–39.
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Smyczynski, M. S., W. P. Segars, M. V. Narayanan, P. H. Pretorius, H. C. Gifford, T. H. Farncombe, E. A. Hoffman, B. M. W. Tsui, and M. A. King. “Modeling the respiratory motion of solitary pulmonary nodules for investigating SPECT tumor imaging.” Ieee Nuclear Science Symposium and Medical Imaging Conference 3 (December 1, 2001): 1371–75.
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Segars, W. P., D. S. Lalush, and B. M. W. Tsui. “Modeling respiratory mechanics in the MCAT and spline-based MCAT phantoms.” Ieee Transactions on Nuclear Science 48, no. 1 I (February 1, 2001): 89–97. https://doi.org/10.1109/23.910837.Full Text
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Faber, T. L., E. V. Garcia, D. S. Lalush, W. P. Segars, and B. M. W. Tsui. “Simulating patient-specific heart shape and motion using SPECT perfusion images with the MCAT phantom.” Proceedings of Spie the International Society for Optical Engineering 4319 (January 1, 2001): 22–26. https://doi.org/10.1117/12.428050.Full Text
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Segars, W. P., D. S. Lalush, and B. M. W. Tsui. “Development of an interactive software application to model patient populations in the 4D NURBS-based Cardiac Torso phantom.” Ieee Nuclear Science Symposium and Medical Imaging Conference 3 (December 1, 2000).
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Tsui, B. M. W., W. P. Segars, and D. S. Lalush. “Effects of upward creep and respiratory motion in myocardial SPECT.” Ieee Transactions on Nuclear Science 47, no. 3 PART 3 (January 1, 2000): 1192–95. https://doi.org/10.1109/23.856568.Full Text
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Tsui, B. M. W., W. P. Segars, and D. S. Lalush. “Effects of upward creep and respiratory motion in myocardial SPECT.” Ieee Transactions on Nuclear Science 47, no. 3 PART 3 (2000): 1192–95.
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Lalush, D. S., W. P. Segars, and B. M. W. Tsui. “Monte Carlo optimization of 4D smoothing methods for gated myocardial perfusion SPECT.” Annual International Conference of the Ieee Engineering in Medicine and Biology Proceedings 2 (December 1, 1999): 1123.
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Paul Segars, W., D. S. Lalush, M. Benjamin, and W. Tsui. “Namic heart phantom.” Ieee Transactions on Nuclear Science 46, no. 3 PART 2 (December 1, 1999): 503–6. https://doi.org/10.1109/23.775570.Full Text
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Segars, W. P., D. S. Lalush, and B. M. W. Tsui. “Next generation MCAT: A realistic spline-based torso phantom.” Annual International Conference of the Ieee Engineering in Medicine and Biology Proceedings 2 (December 1, 1999): 978.
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Segars, W. P., D. S. Lalush, and B. M. W. Tsui. “Realistic spline-based dynamic heart phantom.” Ieee Nuclear Science Symposium and Medical Imaging Conference 2 (January 1, 1999): 1175–78.
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Segars, P., and J. E. McNamee. “Pattern of vascular resistance contributes to blood flow heterogeneity.” Faseb Journal 10, no. 3 (December 1, 1996).
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Book Sections
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Veress, A. I., B. R. Coleman, G. Farrar, W. P. Segars, and B. C. Fabien. “Image-based estimation of passive myocardial properties using finite element modeling.” In Handbook of Imaging in Biological Mechanics, 155–71, 2014. https://doi.org/10.1201/b17566.Full Text
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Zubal, I George, and W Paul Segars. “Anthropomorphic Phantoms: Early Developments and Current Advances.” In MONTE CARLO CALCULATIONS IN NUCLEAR MEDICINE, 2ND EDITION: APPLICATIONS IN DIAGNOSTIC IMAGING, 31–44, 2013.Link to Item
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Zubal, I. G., and W. P. Segars. “Anthropomorphic Phantoms: Early Developments and Current Advances.” In Monte Carlo Calculations in Nuclear Medicine: Applications in Diagnostic Imaging, 31–44, 2012. https://doi.org/10.1201/b13073-8.Full Text
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Segars, W. P., and B. M. W. Tsui. “The MCAT, NCAT, XCAT, and MOBY Computational Human and Mouse Phantoms.” In Handbook of Anatomical Models for Radiation Dosimetry, 105–34, 2009. https://doi.org/10.1201/EBK1420059793-11.Full Text
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Stabin, M. G., M. A. Emmons-Keenan, W. P. Segars, and M. J. Fernald. “The Vanderbilt University Reference Adult and Pediatric Phantom Series.” In Handbook of Anatomical Models for Radiation Dosimetry, 337–46, 2009. https://doi.org/10.1201/EBK1420059793-19.Full Text
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Tsui, B. M. W., and W. P. Segars. “Applications to Nuclear Medicine Imaging and Dosimetry Involving MCAT, NCAT, and MOBY Phantoms.” In Handbook of Anatomical Models for Radiation Dosimetry, 549–66, 2009. https://doi.org/10.1201/EBK1420059793-31.Full Text
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Xu, X. G., M. G. Stabin, W. E. Bolch, and W. P. Segars. “Summary and Future Needs Related to Computational Phantoms.” In Handbook of Anatomical Models for Radiation Dosimetry, 679–84, 2009. https://doi.org/10.1201/EBK1420059793-37.Full Text
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Conference Papers
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Bhattarai, M., S. Sharma, S. Vrbaški, E. Abadi, W. P. Segars, A. Contillo, R. Longo, and E. Samei. “Simulation of the combined effects of charge sharing and pulse pileup in photon-counting CT.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 12031, 2022. https://doi.org/10.1117/12.2612663.Full Text
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Clark, D. P., E. Abadi, N. Felice, W. P. Segars, E. Samei, and C. T. Badea. “Cardiac CT reconstruction for vendor-neutral virtual imaging trials.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 12031, 2022. https://doi.org/10.1117/12.2612950.Full Text
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Dahal, L., F. I. Tushar, E. Abadi, R. B. Fricks, M. Mazurowski, W. P. Segars, E. Samei, and J. Y. Lo. “Virtual versus reality: external validation of COVID-19 classifiers using XCAT phantoms for chest radiography.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 12031, 2022. https://doi.org/10.1117/12.2612975.Full Text
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McCabe, C., M. Zarei, W. P. Segars, E. Samei, and E. Abadi. “Optimization of imaging parameters of an investigational photon-counting CT prototype for lung lesion radiomics.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 12033, 2022. https://doi.org/10.1117/12.2612973.Full Text
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Tanaka, R., W. P. Segars, E. Abadi, S. Minami, and E. Samei. “Optimization of imaging conditions in pediatric dynamic chest radiography: a virtual imaging trial.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 12031, 2022. https://doi.org/10.1117/12.2612720.Full Text
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Tushar, F. I., E. Abadi, S. Sotoudeh-Paima, R. B. Fricks, M. A. Mazurowski, W. P. Segars, E. Samei, and J. Y. Lo. “Virtual vs. reality: External validation of COVID-19 classifiers using XCAT phantoms for chest computed tomography.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 12033, 2022. https://doi.org/10.1117/12.2613010.Full Text
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Tushar, F. I., H. Nujaim, W. Fu, E. Abadi, M. A. Mazurowski, W. P. Segars, E. Samei, and J. Y. Lo. “Quality or quantity: toward a unified approach for multi-organ segmentation in body CT.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 12031, 2022. https://doi.org/10.1117/12.2613101.Full Text
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Abadi, E., G. Jadick, E. A. Hoffman, D. Lynch, W. P. Segars, and E. Samei. “Copd quantifications via ct imaging: Ascertaining the effects of acquisition protocol using virtual imaging trial.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 11595, 2021. https://doi.org/10.1117/12.2581965.Full Text
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Gann, A. M., E. Abadi, J. Hoye, T. J. Sauer, W. P. Segars, H. Chalian, and E. Samei. “An analysis of radiomics features in lung lesions in covid-19.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 11595, 2021. https://doi.org/10.1117/12.2582296.Full Text
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Ishihara, N., R. Tanaka, W. P. Segars, E. Abadi, and E. Samei. “Estimation of lung volume changes from frontal and lateral views of dynamic chest radiography using a convolutional neural network model: A computational phantom study.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 11595, 2021. https://doi.org/10.1117/12.2579948.Full Text
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Sauer, T. J., E. Abadi, W. P. Segars, and E. Samei. “Optimization of CT angiography using physiologically-informed computational plaques, dynamic XCAT phantoms, and physics-based CT simulation.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 11595, 2021. https://doi.org/10.1117/12.2582293.Full Text
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Sugiura, T., R. Tanaka, W. P. Segars, E. Abadi, and E. Samei. “Correlation of respiratory changes in lung density on dynamic chest radiographs with changes in the ct value: A computational phantom study.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 11595, 2021. https://doi.org/10.1117/12.2579973.Full Text
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Zarei, M., E. Abadi, R. Fricks, W. P. Segars, and E. Samei. “A probabilistic conditional adversarial neural network to reduce imaging variation in radiography.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 11595, 2021. https://doi.org/10.1117/12.2582336.Full Text
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Zarei, M., E. Abadi, W. P. Segars, T. Richards, and E. Samei. “Multi-factorial optimization of imaging parameters for quantifying coronary stenosis in cardiac ct.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 11595, 2021. https://doi.org/10.1117/12.2582311.Full Text
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Fu, W., P. W. Segars, S. Sharma, J. Y. Lo, and E. Samei. “IPhantom: An automated framework in generating personalized computational phantoms for organ-based radiation dosimetry.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 11595, 2021. https://doi.org/10.1117/12.2582238.Full Text
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Jadick, G., E. Abadi, B. Harrawood, S. Sharma, W. P. Segars, and E. Samei. “A framework to simulate ct images with tube current modulation.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 11595, 2021. https://doi.org/10.1117/12.2580983.Full Text
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Abadi, Ehsan, William Segars, Shobit Sharma, Francesco Ria, Hamid Chalian, and Ehsan Samei. “Virtual Imaging Trials for Novel Coronavirus Disease (COVID-19),” 2020.
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Ria, Francesco, wanyi Fu, Hamid Chalian, W. Segars, Rafael Fricks, Pegah Khoshpouri, and Ehsan Samei. “Justification of radiological procedures in COVID-19 pandemic based on radiation risk only,” 2020.Open Access Copy
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Ria, Francesco, Wanyi Fu, Jocelyn Hoye, William Segars, Anuj Kapadia, and Ehsan Samei. “Clinical Decision Making in CT: Risk Assessment Comparison Across 12 Risk Metrics in Patient Populations.” In Journal of Medical Physics, 6:e519–e519. Medknow Publications, 2020. https://doi.org/10.1002/mp.14316.Full Text Open Access Copy
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“THE 2020 AAPM ANNUAL MEETING PROGRAM.” In Med Phys, 47:e255-2720, 2020. https://doi.org/10.1002/mp.14316.Full Text Open Access Copy Link to Item
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Abadi, E., J. Rajagopal, T. Sauer, E. Jones, W. P. Segars, and E. Samei. “Optimization of energy thresholds in photon-counting CT via a virtual clinical trial.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 11312, 2020. https://doi.org/10.1117/12.2549055.Full Text
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Gullberg, Grant, Uttam Shrestha, Alexander Veress, W Paul Segars, Jing Liu, Karen Ordovas, and Youngho Seo. “NOVEL METHODOLGY FOR MEASURING REGIONAL MYOCARDIAL EFFICIENCY.” In Journal of Nuclear Medicine, Vol. 61, 2020.Link to Item
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Samei, E., E. Abadi, A. Kapadia, J. Lo, M. Mazurowski, and P. Segars. “Virtual imaging trials: An emerging experimental paradigm in imaging research and practice.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 11312, 2020. https://doi.org/10.1117/12.2549818.Full Text
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Tanaka, R., E. Samei, W. P. Segars, E. Abadi, I. Matsumoto, M. Tamura, N. Ishihara, and T. Yamashiro. “Prediction of pleural invasion of lung cancer with dynamic chest radiography: A simulation study.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 11312, 2020. https://doi.org/10.1117/12.2547464.Full Text
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Veress, Alexander, Uttam Shrestha, Jing Liu, Karen Ordovas, Grant Gullberg, W Paul Segars, and Youngho Seo. “IN VIVO MEASURE OF CARDIAC EFFICIENCY USING HYBRID PET/MRI TECHNOLOGY.” In Journal of Nuclear Medicine, Vol. 60. SOC NUCLEAR MEDICINE INC, 2019.Link to Item
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Liu, Y., W. Fu, V. Selvakumaran, M. Phelan, W. P. Segars, E. Samei, M. Mazurowski, J. Y. Lo, G. D. Rubin, and R. Henao. “Deep learning of 3D computed tomography (CT) images for organ segmentation using 2D multi-channel SegNet model.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 10954, 2019. https://doi.org/10.1117/12.2512887.Full Text
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Richards, T., A. Ivanov, P. Segars, U. Hoffmann, and E. Samei. “Cardiac CT estimability index: An ideal estimator in the presence of noise and motion.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 10948, 2019. https://doi.org/10.1117/12.2513035.Full Text
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Sauer, T. J., E. Abadi, P. Segars, and E. Samei. “Anatomically- and computationally-informed hepatic contrast perfusion simulations for use in virtual clinical trials.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 10948, 2019. https://doi.org/10.1117/12.2513465.Full Text
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Tanaka, R., E. Samei, P. Segars, E. Abadi, H. Roth, H. Oda, and K. Mori. “Dynamic chest radiography for pulmonary function diagnosis: A validation study using 4D extended cardiac-torso (XCAT) phantom.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 10948, 2019. https://doi.org/10.1117/12.2512332.Full Text
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Veress, A. I., W. P. Segars, and E. Samei. “Utilizing deformable image registration to create new living human heart models for imaging simulation.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 10948, 2019. https://doi.org/10.1117/12.2512939.Full Text
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Abadi, Ehsan, Brian Harrawood, Jayasai Rajagopal, Shobhit Sharma, Anuj Kapadia, Martin Sedlmair, Juan Carlos Ramirez-Giraldo, Karl Stierstorfer, W Paul Segars, and Ehsan Samei. “A framework for realistic virtual clinical trials in photon counting computed tomography.” In Medical Imaging 2019: Physics of Medical Imaging, 10948:109484F-109484F, 2019.
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Abadi, Ehsan, W Paul Segars, Brian Harrawood, Shobhit Sharma, Thomas Sauer, Anuj Kapadia, and Ehsan Samei. “Trade-off between spatial details and motion artifact in multi-detector CT: A virtual clinical trial with 4D textured human models.” In Medical Imaging 2019: Physics of Medical Imaging, 10948:109482R-109482R, 2019.
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Fu, Wanyi, Shobhit Sharma, Taylor Smith, Rui Hou, Ehsan Abadi, Vignesh Selvakumaran, Ruixiang Tang, et al. “Multi-organ segmentation in clinical-computed tomography for patient-specific image quality and dose metrology.” In Medical Imaging 2019: Physics of Medical Imaging, 10948:1094829–1094829, 2019.
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Sharma, Shobhit, Ehsan Abadi, Anuj Kapadia, W Paul Segars, and Ehsan Samei. “A comprehensive GPU-based framework for scatter estimation in single source, dual source, and photon-counting CT.” In Medical Imaging 2019: Physics of Medical Imaging, 10948:109482V-109482V, 2019.
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Fu, W., F. Ria, J. Wilson, A. J. Kapadia, W. P. Segars, and E. Samei. “Effective Dose for Computed Tomography in Large, Clinical Populations,” 2018.
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Ria, F., Wanyi Fu, Yakun Zhang, Jocelyn Hoye, W. P. Segars, A. J. Kapadia, and E. Samei. “Characterization of Radiation Risk across a Clinical CT Patient Population: Comparison across 12 Risks Metrics,” 2018.
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Abadi, E., B. Harrawood, A. Kapadia, W. P. Segars, and E. Samei. “Development of a fast, voxel-based, and scanner-specific CT simulator for image-quality-based virtual clinical trials.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 10573, 2018. https://doi.org/10.1117/12.2293123.Full Text
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Abadi, E., W. P. Segars, B. Harrawood, A. Kapadia, and E. Samei. “Virtual clinical trial in action: Textured XCAT phantoms and scanner-specific CT simulator to characterize noise across CT reconstruction algorithms.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 10573, 2018. https://doi.org/10.1117/12.2294599.Full Text
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Rajagopal, J., G. M. Sturgeon, X. C. Chen, T. J. Sauer, Y. Ren, W. P. Segars, and J. Y. Lo. “Evaluation of statistical breast phantoms with higher resolution.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 10573, 2018. https://doi.org/10.1117/12.2294049.Full Text
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Richards, T., P. Segars, and E. Samei. “Variability of stenosis characterization: Impact of coronary vessel motion in cardiac CT.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 10573, 2018. https://doi.org/10.1117/12.2293261.Full Text
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Fu, Wanyi, William P. Segars, Ehsan Abadi, Shobhit Sharma, Anuj J. Kapadia, and Ehsan Samei. “From patient-informed to patient-specific organ dose estimation in clinical computed tomography.” In Medical Imaging 2018: Physics of Medical Imaging, 10573:1057315–1057315, 2018.
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Sharma, Shobhit, Anuj Kapadia, Ehsan Abadi, Wanyi Fu, W Paul Segars, and Ehsan Samei. “A rapid GPU-based Monte-Carlo simulation tool for individualized dose estimations in CT.” In Medical Imaging 2018: Physics of Medical Imaging, 10573:105733V-105733V, 2018.
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Abadi, E., G. M. Sturgeon, G. Agasthya, B. Harrawood, C. Hoeschen, A. Kapadia, W. P. Segars, and E. Samei. “Airways, vasculature, and interstitial tissue: Anatomically informed computational modeling of human lungs for virtual clinical trials.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 10132, 2017. https://doi.org/10.1117/12.2254739.Full Text
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Fu, W., G. M. Sturgeon, G. Agasthya, W. P. Segars, A. J. Kapadia, and E. Samei. “Estimation of breast dose reduction potential for organ-based tube current modulated CT with wide dose reduction arc.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 10132, 2017. https://doi.org/10.1117/12.2255797.Full Text
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Hoye, J., Y. Zhang, G. Agasthya, G. Sturgeon, A. Kapadia, W. P. Segars, and E. Samei. “An atlas-based organ dose estimator for tomosynthesis and radiography.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 10132, 2017. https://doi.org/10.1117/12.2255583.Full Text
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Sauer, T. J., C. G. Graff, R. Zeng, M. Santana, G. M. Sturgeon, H. Bosmans, S. J. Glick, X. C. Chen, W. P. Segars, and J. Y. Lo. “Detectability of artificial lesions in anthropomorphic virtual breast phantoms of variable glandular fraction.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 10132, 2017. https://doi.org/10.1117/12.2255896.Full Text
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Sturgeon, G. M., T. W. Richards, E. Samei, and W. P. Segars. “Improved virtual cardiac phantom with variable diastolic filling rates and coronary artery velocities.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 10132, 2017. https://doi.org/10.1117/12.2255572.Full Text
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Becchetti, M. F., J. B. Solomon, W. P. Segars, and E. Samei. “Synthesized interstitial lung texture for use in anthropomorphic computational phantoms.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 9783, 2016. https://doi.org/10.1117/12.2217135.Full Text
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Divel, S. E., W. P. Segars, S. Christensen, M. Wintermark, M. G. Lansberg, and N. J. Pelc. “Development of a realistic, dynamic digital brain phantom for CT perfusion validation.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 9783, 2016. https://doi.org/10.1117/12.2214997.Full Text
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Fu, W., X. Tian, G. Sturgeon, G. Agasthya, W. P. Segars, M. M. Goodsitt, E. A. Kazerooni, and E. Samei. “Estimation of breast dose saving potential using a breast positioning technique for organ-based tube current modulated CT.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 9783, 2016. https://doi.org/10.1117/12.2217239.Full Text
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Fu, W., X. Tian, P. Sahbaee, Y. Zhang, W. P. Segars, and E. Samei. “Organ dose conversion coefficients for tube current modulated CT protocols for an adult population.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 9783, 2016. https://doi.org/10.1117/12.2217271.Full Text
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Sanders, J. W., X. Tian, W. P. Segars, J. Boone, and E. Samei. “An automated technique for estimating patient-specific regional imparted energy and dose in TCM CT exams.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 9783, 2016. https://doi.org/10.1117/12.2216413.Full Text
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Sturgeon, G. M., D. J. Tward, M. Ketcha, J. T. Ratnanather, M. I. Miller, S. Park, W. P. Segars, and J. Y. Lo. “Eigenbreasts for statistical breast phantoms.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 9783, 2016. https://doi.org/10.1117/12.2216398.Full Text
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Elangovan, P., A. Rashidnasab, A. Mackenzie, D. R. Dance, K. C. Young, H. Bosmans, W. P. Segars, and K. Wells. “Performance comparison of breast imaging modalities using a 4AFC human observer study.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 9412, 2015. https://doi.org/10.1117/12.2081878.Full Text
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Kiarashi, N., L. W. Nolte, J. Y. Lo, W. P. Segars, S. V. Ghate, and E. Samei. “The impact of breast structure on lesion detection in breast tomosynthesis.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 9412, 2015. https://doi.org/10.1117/12.2082473.Full Text
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Liptak, C. L., D. Tovey, W. P. Segars, F. D. Dong, and X. Li. “Anatomy-based transmission factors for technique optimization in portable chest x-ray.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 9412, 2015. https://doi.org/10.1117/12.2082056.Full Text
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Muryn, J. S., A. G. Morgan, W. P. Segars, C. L. Liptak, F. F. Dong, A. N. Primak, and X. Li. “Analysis of uncertainties in Monte Carlo simulated organ dose for chest CT.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 9412, 2015. https://doi.org/10.1117/12.2076067.Full Text
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Sahbaee, P., Y. Li, P. Segars, D. Marin, R. Nelson, and E. Samei. “Determination of contrast media administration to achieve a targeted contrast enhancement in CT.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 9412, 2015. https://doi.org/10.1117/12.2082261.Full Text
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Tian, X., W. P. Segars, R. L. Dixon, and E. Samei. “Convolution-based estimation of organ dose in tube current modulated CT.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 9412, 2015. https://doi.org/10.1117/12.2082238.Full Text
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Nolte, A., N. Kiarashi, E. Samei, W. P. Segars, and J. Y. Lo. “A second generation of physical anthropomorphic 3D breast phantoms based on human subject data.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 9033, 2014. https://doi.org/10.1117/12.2043703.Full Text
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Segars, W. P., A. I. Veress, J. R. Wells, G. M. Sturgeon, N. Kiarashi, J. Y. Lo, E. Samei, and J. T. Dobbins. “Population of 100 realistic, patient-based computerized breast phantoms for multi-modality imaging research.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 9033, 2014. https://doi.org/10.1117/12.2043868.Full Text
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Bond, J., D. Frush, E. Samei, and W. P. Segars. “Simulation of anatomical texture in voxelized XCAT phantoms.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 8668, 2013. https://doi.org/10.1117/12.2008422.Full Text
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Kiarashi, N., G. M. Sturgeon, L. W. Nolte, J. Y. Lo, J. T. D. III, W. P. Segars, and E. Samei. “Development of matched virtual and physical breast phantoms based on patient data.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 8668, 2013. https://doi.org/10.1117/12.2008406.Full Text
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Wilson, J. M., K. L. Chisholm, J. D. Oldan, W. P. Segars, T. G. Turkington, and B. B. Chin. “Patient-specific model of NaF PET to facilitate multicenter clinical trial PET imaging protocols and analysis: preliminary results of a CT-based simulation.” In Journal of Nuclear Medicine, 54:26–27, 2013.
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Kiarashi, N., Y. Lin, W. P. Segars, S. V. Ghate, L. Ikejimba, B. Chen, J. Y. Lo, J. T. Dobbins, L. W. Nolte, and E. Samei. “Development of a dynamic 4D anthropomorphic breast phantom for contrast-based breast imaging.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 8313, 2012. https://doi.org/10.1117/12.913332.Full Text
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Mishra, P., S. S. James, W. Segars, R. Berbeco, and J. Lewis. “TU‐C‐213CD‐06: Patient Lung Tumor Trajectory Based Modified‐XCAT and Its Applications.” In Medical Physics, 39:3903, 2012. https://doi.org/10.1118/1.4735933.Full Text
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Zhang, Y., X. li, W. Segars, and E. Samei. “TH‐A‐214‐02: Organ Dose, Effective Dose, and Dose Conversion Coefficients in Adult CT: Comparison of Mathematical, XCAT, and ICRP Reference Phantoms.” In Medical Physics, 38:3842–43, 2011. https://doi.org/10.1118/1.3613467.Full Text
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Dobbins, J. T., J. R. Wells, W. P. Segars, C. M. Li, and C. J. N. Kigongo. “Initial investigation into lower-cost CT for resource limited regions of the world.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 7622, 2010. https://doi.org/10.1117/12.844293.Full Text
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Li, X., E. Samei, W. P. Segars, G. M. Sturgeon, J. G. Colsher, and D. P. Frush. “Patient-specific radiation dose and cancer risk estimation in pediatric chest CT: A study in 30 patients.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 7622, 2010. https://doi.org/10.1117/12.845491.Full Text
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Li, C. M., W. P. Segars, J. Y. Lo, A. I. Veress, J. M. Boone, and J. T. Dobbins. “Computerized 3D breast phantom with enhanced High-Resolution detail.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 7258, 2009. https://doi.org/10.1117/12.813529.Full Text
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Dey, Joyoni, William P. Segars, P Hendrik Pretorius, and Michael A. King. “Estimation and Correction of Irregular Respiratory motion of the Heart in Presence of Partial Angle Effects Due to Amplitude Binning in SPECT.” In 2008 Ieee Nuclear Science Symposium and Medical Imaging Conference (2008 Nss/Mic), Vols 1 9, 2931-+. IEEE, 2009.Link to Item
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Smyczynski, M. S., H. C. Gifford, A. Lehovich, J. E. McNamara, W. P. Segars, J. Dey, and M. A. King. “Effectiveness of three alternative strategies in reducing the degrading impact of respiratory motion on the detection of small pulmonary nodules in SPECT imaging.” In 2008 Ieee Nuclear Science Symposium and Medical Imaging Conference (2008 Nss/Mic), Vols 1 9, 2938-+. IEEE, 2009.Link to Item
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Li, C. M., W. P. Segars, J. Y. Lo, A. I. Veress, J. M. Boone, and J. T. Dobbins. “Three-dimensional computer generated breast phantom based on empirical data.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 6913, 2008. https://doi.org/10.1117/12.772185.Full Text
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Baydush, A., D. Godfrey, and W. Segars. “SU‐GG‐J‐93: Feasibility Study On Artifact Reduction Using Dual Energy Digital Tomosynthesis.” In Medical Physics, 35:2700, 2008. https://doi.org/10.1118/1.2961643.Full Text
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Baydush, A., D. Godfrey, and W. Segars. “SU‐GG‐J‐94: Feasibility Study On the Efficacy of Dual Energy Cine Imaging in Radiation Therapy for Lung Cancer.” In Medical Physics, 35:2700, 2008. https://doi.org/10.1118/1.2961644.Full Text
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hu, N., L. Cerviño, W. Segars, J. Lewis, N. Tyagi, A. Mundt, C. Yashar, J. Shan, and S. Jiang. “TH‐D‐AUD A‐08: A Method for Generating Large Datasets of Patient Geometries for Radiotherapy Treatment Planning Studies.” In Medical Physics, 35:2983–84, 2008. https://doi.org/10.1118/1.2962901.Full Text
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Roper, J. R., J. E. Bowsher, W. P. Segars, and F. Yin. “Onboard SPECT for Biological Target Localization.” In International Journal of Radiation Oncology*Biology*Physics, 69:S642–43. Elsevier BV, 2007. https://doi.org/10.1016/j.ijrobp.2007.07.1982.Full Text
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Hauser, M. A., J. W. Walter, R. W. Walters, M. Maready, S. Takeuchi, W. P. Segars, C. M. Hulette, et al. “Identification of candidate genes for Parkinson disease (PD)by the convergence of genetic linkage and association data with gene expression in the substantia nigra.” In American Journal of Human Genetics, 71:467–467. UNIV CHICAGO PRESS, 2002.Link to Item
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