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Immunofluorescence detection for fiber optics chemical and biological sensors

Publication ,  Journal Article
Vo-Dinn, T; Tromberg, BJ; Sepaniak, MJ; Griffin, GD; Ambrose, KR; Santella, RM
Published in: Proceedings of SPIE - The International Society for Optical Engineering
April 27, 1988

This paper presents the development and application of immunofluorescence spectroscopy in fiberoptics-based chemical and biological sensors. Focus is on a fluoroimmuno-sensor (FIS), which combines the excellent specificity of the antigen-antibody reaction and the high sensitivity of laser excitation and the versatility of fiberoptics technology. The FIS can detect 40 attomoles (10-18 mole) of benzo(a)pyrene tetrol, a DNA-adduct product of the carcinogen benzo(a)pyrene.

Duke Scholars

Published In

Proceedings of SPIE - The International Society for Optical Engineering

DOI

EISSN

1996-756X

ISSN

0277-786X

Publication Date

April 27, 1988

Volume

910

Start / End Page

87 / 94

Related Subject Headings

  • 5102 Atomic, molecular and optical physics
  • 4009 Electronics, sensors and digital hardware
  • 4006 Communications engineering
 

Citation

APA
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ICMJE
MLA
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Vo-Dinn, T., Tromberg, B. J., Sepaniak, M. J., Griffin, G. D., Ambrose, K. R., & Santella, R. M. (1988). Immunofluorescence detection for fiber optics chemical and biological sensors. Proceedings of SPIE - The International Society for Optical Engineering, 910, 87–94. https://doi.org/10.1117/12.945444

Published In

Proceedings of SPIE - The International Society for Optical Engineering

DOI

EISSN

1996-756X

ISSN

0277-786X

Publication Date

April 27, 1988

Volume

910

Start / End Page

87 / 94

Related Subject Headings

  • 5102 Atomic, molecular and optical physics
  • 4009 Electronics, sensors and digital hardware
  • 4006 Communications engineering