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Immunofluorescence Detection for Fiber Optics Chemical and Biological Sensors

Publication ,  Journal Article
Vo-Dinh, T; Tromberg, BJ; Griffin, GD; Ambrose, KR; Sepaniak, MJ; Santella, RM
Published in: Proceedings of SPIE - The International Society for Optical Engineering
April 27, 1988

This paper presents the development and application of immunofluorescence spectroscopy in fiberoptics-based chemical and biological sensors. Focus is on a fluoroimmuno-sensor (FIS), which combines the excellent specificity of the antigen-antibody reaction and the high sensitivity of laser excitation and the versatility of fiberoptics technology. The FIS can detect 40 attomoles (10-18 mole) of benzo(a)pyrene tetrol, a DNA-adduct product of the carcinogen benzo(a)pyrene. © 1988 SPIE.

Duke Scholars

Published In

Proceedings of SPIE - The International Society for Optical Engineering

DOI

EISSN

1996-756X

ISSN

0277-786X

Publication Date

April 27, 1988

Volume

910

Start / End Page

87 / 94

Related Subject Headings

  • 5102 Atomic, molecular and optical physics
  • 4009 Electronics, sensors and digital hardware
  • 4006 Communications engineering
 

Citation

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ICMJE
MLA
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Vo-Dinh, T., Tromberg, B. J., Griffin, G. D., Ambrose, K. R., Sepaniak, M. J., & Santella, R. M. (1988). Immunofluorescence Detection for Fiber Optics Chemical and Biological Sensors. Proceedings of SPIE - The International Society for Optical Engineering, 910, 87–94. https://doi.org/10.1117/12.945444
Vo-Dinh, T., B. J. Tromberg, G. D. Griffin, K. R. Ambrose, M. J. Sepaniak, and R. M. Santella. “Immunofluorescence Detection for Fiber Optics Chemical and Biological Sensors.” Proceedings of SPIE - The International Society for Optical Engineering 910 (April 27, 1988): 87–94. https://doi.org/10.1117/12.945444.
Vo-Dinh T, Tromberg BJ, Griffin GD, Ambrose KR, Sepaniak MJ, Santella RM. Immunofluorescence Detection for Fiber Optics Chemical and Biological Sensors. Proceedings of SPIE - The International Society for Optical Engineering. 1988 Apr 27;910:87–94.
Vo-Dinh, T., et al. “Immunofluorescence Detection for Fiber Optics Chemical and Biological Sensors.” Proceedings of SPIE - The International Society for Optical Engineering, vol. 910, Apr. 1988, pp. 87–94. Scopus, doi:10.1117/12.945444.
Vo-Dinh T, Tromberg BJ, Griffin GD, Ambrose KR, Sepaniak MJ, Santella RM. Immunofluorescence Detection for Fiber Optics Chemical and Biological Sensors. Proceedings of SPIE - The International Society for Optical Engineering. 1988 Apr 27;910:87–94.

Published In

Proceedings of SPIE - The International Society for Optical Engineering

DOI

EISSN

1996-756X

ISSN

0277-786X

Publication Date

April 27, 1988

Volume

910

Start / End Page

87 / 94

Related Subject Headings

  • 5102 Atomic, molecular and optical physics
  • 4009 Electronics, sensors and digital hardware
  • 4006 Communications engineering