Adverse drug reactions with halogenated anesthetics.
Publication
, Journal Article
Kharasch, ED
Published in: Clin Pharmacol Ther
July 2008
Problems with organ toxicity from the halogenated volatile anesthetics have influenced clinical practice, anesthetic selection, and drug development for half a century.(1,2) In turn, investigations that elucidated the mechanisms of volatile anesthetics adverse effects identified new mechanisms, provided remarkable insights into human toxicology, and represented seminal contributions to clinical pharmacology. This review focuses on adverse organ effects (hepatic, renal, and others) that are attributable to anesthetic metabolism and/or degradation. Routine reversible effects on pulmonary, cardiac, and other organ functions are not addressed.
Duke Scholars
Published In
Clin Pharmacol Ther
DOI
EISSN
1532-6535
Publication Date
July 2008
Volume
84
Issue
1
Start / End Page
158 / 162
Location
United States
Related Subject Headings
- Pharmacology & Pharmacy
- Liver
- Kidney
- Hydrocarbons, Halogenated
- Humans
- Halothane
- Anesthetics, Inhalation
- 3214 Pharmacology and pharmaceutical sciences
- 1115 Pharmacology and Pharmaceutical Sciences
Citation
APA
Chicago
ICMJE
MLA
NLM
Kharasch, E. D. (2008). Adverse drug reactions with halogenated anesthetics. Clin Pharmacol Ther, 84(1), 158–162. https://doi.org/10.1038/clpt.2008.97
Kharasch, E. D. “Adverse drug reactions with halogenated anesthetics.” Clin Pharmacol Ther 84, no. 1 (July 2008): 158–62. https://doi.org/10.1038/clpt.2008.97.
Kharasch ED. Adverse drug reactions with halogenated anesthetics. Clin Pharmacol Ther. 2008 Jul;84(1):158–62.
Kharasch, E. D. “Adverse drug reactions with halogenated anesthetics.” Clin Pharmacol Ther, vol. 84, no. 1, July 2008, pp. 158–62. Pubmed, doi:10.1038/clpt.2008.97.
Kharasch ED. Adverse drug reactions with halogenated anesthetics. Clin Pharmacol Ther. 2008 Jul;84(1):158–162.
Published In
Clin Pharmacol Ther
DOI
EISSN
1532-6535
Publication Date
July 2008
Volume
84
Issue
1
Start / End Page
158 / 162
Location
United States
Related Subject Headings
- Pharmacology & Pharmacy
- Liver
- Kidney
- Hydrocarbons, Halogenated
- Humans
- Halothane
- Anesthetics, Inhalation
- 3214 Pharmacology and pharmaceutical sciences
- 1115 Pharmacology and Pharmaceutical Sciences