Current Appointments & Affiliations
Merel H. Harmel Distinguished Professor of Anesthesiology
·
2019 - Present
Anesthesiology, General, Vascular, High Risk Transplant & Critical Care,
Anesthesiology
Professor of Anesthesiology
·
2018 - Present
Anesthesiology, General, Vascular, High Risk Transplant & Critical Care,
Anesthesiology
Recent Publications
Opioids Reconsidered: From Antinociception to Potential Organ Protection.
Journal Article Anesth Analg · May 1, 2026 Full text Open Access Link to item CitePopulation Pharmacokinetics of Intravenous Methadone Enantiomers in Adults: A Comprehensive Model.
Journal Article Clin Pharmacol Ther · March 2026 Methadone is a utilitarian opioid with growing use for anesthesia and postoperative pain. Methadone pharmacokinetic models have evolved over time; however, there is no comprehensive population pharmacokinetic model. This investigation developed a populatio ... Full text Link to item CitePharmacogenetic influence on bupropion bioactivation and clinical outcomes in major depressive disorder.
Journal Article The Journal of pharmacology and experimental therapeutics · March 2026 This investigation addressed influences of CYP2B6 and CYP2C19 genetic polymorphisms on steady-state bupropion disposition, antidepressant outcomes and side effects, and evaluated influences of pharmacokinetic variability on pharmacogenetic results. This wa ... Full text CiteRecent Grants
Revolutionizing Pediatric Tonsillectomy Pharmacology and Therapeutics
ResearchCo Investigator · Awarded by Eunice Kennedy Shriver National Institute of Child Health and Human Development · 2024 - 2029Optimizing Pain Management in Infants and Young Children Undergoing Cleft Palate Repair
ResearchCo Investigator · Awarded by Gerber Foundation · 2026 - 2028Integrated Training in Anesthesiology Research
Inst. Training Prgm or CMEMentor · Awarded by National Institute of General Medical Sciences · 1996 - 2027View All Grants
Education
Northwestern University ·
1984
M.D.
Northwestern University ·
1983
Ph.D.