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Photoacoustic microscopy: principles and biomedical applications.

Publication ,  Journal Article
Liu, W; Yao, J
Published in: Biomedical engineering letters
May 2018

Photoacoustic microscopy (PAM) has become an increasingly popular technology for biomedical applications, providing anatomical, functional, and molecular information. In this concise review, we first introduce the basic principles and typical system designs of PAM, including optical-resolution PAM and acoustic-resolution PAM. The major imaging characteristics of PAM, i.e. spatial resolutions, penetration depth, and scanning approach are discussed in detail. Then, we introduce the major biomedical applications of PAM, including anatomical imaging across scales from cellular level to organismal level, label-free functional imaging using endogenous biomolecules, and molecular imaging using exogenous contrast agents. Lastly, we discuss the technical and engineering challenges of PAM in the translation to potential clinical impacts.

Duke Scholars

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Published In

Biomedical engineering letters

DOI

EISSN

2093-985X

ISSN

2093-9868

Publication Date

May 2018

Volume

8

Issue

2

Start / End Page

203 / 213
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Liu, W., & Yao, J. (2018). Photoacoustic microscopy: principles and biomedical applications. Biomedical Engineering Letters, 8(2), 203–213. https://doi.org/10.1007/s13534-018-0067-2
Liu, Wei, and Junjie Yao. “Photoacoustic microscopy: principles and biomedical applications.Biomedical Engineering Letters 8, no. 2 (May 2018): 203–13. https://doi.org/10.1007/s13534-018-0067-2.
Liu W, Yao J. Photoacoustic microscopy: principles and biomedical applications. Biomedical engineering letters. 2018 May;8(2):203–13.
Liu, Wei, and Junjie Yao. “Photoacoustic microscopy: principles and biomedical applications.Biomedical Engineering Letters, vol. 8, no. 2, May 2018, pp. 203–13. Epmc, doi:10.1007/s13534-018-0067-2.
Liu W, Yao J. Photoacoustic microscopy: principles and biomedical applications. Biomedical engineering letters. 2018 May;8(2):203–213.
Journal cover image

Published In

Biomedical engineering letters

DOI

EISSN

2093-985X

ISSN

2093-9868

Publication Date

May 2018

Volume

8

Issue

2

Start / End Page

203 / 213