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Stimuli-Responsive Supramolecular Hydrogels and Their Applications in Regenerative Medicine.

Publication ,  Journal Article
Hoque, J; Sangaj, N; Varghese, S
Published in: Macromol Biosci
January 2019

Supramolecular hydrogels are a class of self-assembled network structures formed via non-covalent interactions of the hydrogelators. These hydrogels capable of responding to external stimuli are considered to be smart materials due to their ability to undergo sol-gel and/or gel-sol transition upon subtle changes in their surroundings. Such stimuli-responsive hydrogels are intriguing biomaterials with applications in tissue engineering, delivery of cells and drugs, modulating tissue environment to promote innate tissue repair, and imaging for medical diagnostics among others. This review summarizes the recent developments in stimuli-responsive supramolecular hydrogels and their potential applications in regenerative medicine. Specifically, various structural aspects of supramolecular hydrogelators involved in self-assembly, the role of external stimuli in tuning/controlling their phase transitions, and how these functions could be harnessed to advance applications in regenerative medicine are focused on. Finally, the key challenges and future prospects for these versatile materials are briefly described.

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Published In

Macromol Biosci

DOI

EISSN

1616-5195

Publication Date

January 2019

Volume

19

Issue

1

Start / End Page

e1800259

Location

Germany

Related Subject Headings

  • Tissue Engineering
  • Regenerative Medicine
  • Polymers
  • Hydrogels
  • Humans
  • Biocompatible Materials
  • 4003 Biomedical engineering
  • 3403 Macromolecular and materials chemistry
  • 0904 Chemical Engineering
  • 0903 Biomedical Engineering
 

Citation

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Hoque, J., Sangaj, N., & Varghese, S. (2019). Stimuli-Responsive Supramolecular Hydrogels and Their Applications in Regenerative Medicine. Macromol Biosci, 19(1), e1800259. https://doi.org/10.1002/mabi.201800259
Hoque, Jiaul, Nivedita Sangaj, and Shyni Varghese. “Stimuli-Responsive Supramolecular Hydrogels and Their Applications in Regenerative Medicine.Macromol Biosci 19, no. 1 (January 2019): e1800259. https://doi.org/10.1002/mabi.201800259.
Hoque J, Sangaj N, Varghese S. Stimuli-Responsive Supramolecular Hydrogels and Their Applications in Regenerative Medicine. Macromol Biosci. 2019 Jan;19(1):e1800259.
Hoque, Jiaul, et al. “Stimuli-Responsive Supramolecular Hydrogels and Their Applications in Regenerative Medicine.Macromol Biosci, vol. 19, no. 1, Jan. 2019, p. e1800259. Pubmed, doi:10.1002/mabi.201800259.
Hoque J, Sangaj N, Varghese S. Stimuli-Responsive Supramolecular Hydrogels and Their Applications in Regenerative Medicine. Macromol Biosci. 2019 Jan;19(1):e1800259.
Journal cover image

Published In

Macromol Biosci

DOI

EISSN

1616-5195

Publication Date

January 2019

Volume

19

Issue

1

Start / End Page

e1800259

Location

Germany

Related Subject Headings

  • Tissue Engineering
  • Regenerative Medicine
  • Polymers
  • Hydrogels
  • Humans
  • Biocompatible Materials
  • 4003 Biomedical engineering
  • 3403 Macromolecular and materials chemistry
  • 0904 Chemical Engineering
  • 0903 Biomedical Engineering