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Modeling "Textured" Bones in Virtual Human Phantoms.

Publication ,  Journal Article
Abadi, E; Segars, WP; Sturgeon, GM; Harrawood, B; Kapadia, A; Samei, E
Published in: IEEE Trans Radiat Plasma Med Sci
January 2019

The purpose of this study was to develop detailed and realistic models of the cortical and trabecular bones in the spine, ribs, and sternum and incorporate them into the library of virtual human phantoms (XCAT). Cortical bone was modeled by 3D morphological erosion of XCAT homogenously defined bones with an average thickness measured from the CT dataset upon which each individual XCAT phantom was based. The trabecular texture was modeled using a power law synthesis algorithm where the parameters were tuned using high-resolution anatomical images of the Human Visible Female. The synthesized bone textures were added into the XCAT phantoms. To qualitatively evaluate the improved realism of the bone modeling, CT simulations of the XCAT phantoms were acquired with and without the textured bone modeling. The 3D power spectrum of the anatomical images exhibited a power law behavior (R2 = 0.84), as expected in fractal and porous textures. The proposed texture synthesis algorithm was able to synthesize textures emulating real anatomical images, with the simulated CT images with the prototyped bones were more realistic than those simulated with the original XCAT models. Incorporating intra-organ structures, the "textured" phantoms are envisioned to be used to conduct virtual clinical trials in the context of medical imaging in cases where the actual trials are infeasible due to the lack of ground truth, cost, or potential risks to the patients.

Duke Scholars

Published In

IEEE Trans Radiat Plasma Med Sci

DOI

ISSN

2469-7311

Publication Date

January 2019

Volume

3

Issue

1

Start / End Page

47 / 53

Location

United States
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Abadi, E., Segars, W. P., Sturgeon, G. M., Harrawood, B., Kapadia, A., & Samei, E. (2019). Modeling "Textured" Bones in Virtual Human Phantoms. IEEE Trans Radiat Plasma Med Sci, 3(1), 47–53. https://doi.org/10.1109/TRPMS.2018.2828083
Abadi, Ehsan, William P. Segars, Gregory M. Sturgeon, Brian Harrawood, Anuj Kapadia, and Ehsan Samei. “Modeling "Textured" Bones in Virtual Human Phantoms.IEEE Trans Radiat Plasma Med Sci 3, no. 1 (January 2019): 47–53. https://doi.org/10.1109/TRPMS.2018.2828083.
Abadi E, Segars WP, Sturgeon GM, Harrawood B, Kapadia A, Samei E. Modeling "Textured" Bones in Virtual Human Phantoms. IEEE Trans Radiat Plasma Med Sci. 2019 Jan;3(1):47–53.
Abadi, Ehsan, et al. “Modeling "Textured" Bones in Virtual Human Phantoms.IEEE Trans Radiat Plasma Med Sci, vol. 3, no. 1, Jan. 2019, pp. 47–53. Pubmed, doi:10.1109/TRPMS.2018.2828083.
Abadi E, Segars WP, Sturgeon GM, Harrawood B, Kapadia A, Samei E. Modeling "Textured" Bones in Virtual Human Phantoms. IEEE Trans Radiat Plasma Med Sci. 2019 Jan;3(1):47–53.

Published In

IEEE Trans Radiat Plasma Med Sci

DOI

ISSN

2469-7311

Publication Date

January 2019

Volume

3

Issue

1

Start / End Page

47 / 53

Location

United States