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MRI of posterior eye shape and its associations with myopia and ethnicity.

Publication ,  Journal Article
Lim, LS; Matsumura, S; Htoon, HM; Tian, J; Lim, SB; Sensaki, S; Chen, C; Hilal, S; Wong, TY; Cheng, CY; Kuo, A; Saw, SM
Published in: Br J Ophthalmol
September 2020

PURPOSE: To evaluate posterior eye shape variations across a wide refractive error range using brain MRI in a multiethnic cohort. METHODS: Adult subjects in the multiethnic Singapore Epidemiology of Eye Disease study were included. Spherical equivalent (SE) was measured using subjective refraction, and axial length (AL) was measured using optical biometry. MRI was performed using a 3-Tesla whole body scanner with a 32-channel head coil. The radii and asphericity based on fitting of the posterior two-thirds of the eye (240°) were calculated. The refractive error status was categorised as myopic (SE<-0.5 D) or non-myopic (SE≥-0.5 D). RESULTS: A total of 450 adult participants (mean age 64.2±6.5 years old) were included. Less oblate asphericity was associated with more myopic SE, longer AL and with a refractive error categorisation of myopia (p<0.001 for all). Asphericity values were less oblate in myopic compared with non-myopic eyes (p<0.001). Multivariate analysis showed that Chinese subjects had less oblate eyes than Malay and Indian subjects, especially in non-myopic eyes. CONCLUSIONS: A less oblate posterior eye shape was associated with myopic eyes. Chinese eyes have less oblate shapes than Malay and Indian eyes, especially in non-myopic eyes.

Duke Scholars

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Published In

Br J Ophthalmol

DOI

EISSN

1468-2079

Publication Date

September 2020

Volume

104

Issue

9

Start / End Page

1239 / 1245

Location

England

Related Subject Headings

  • Vision Tests
  • Singapore
  • Posterior Eye Segment
  • Ophthalmology & Optometry
  • Myopia
  • Middle Aged
  • Male
  • Magnetic Resonance Imaging
  • Humans
  • Female
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Lim, L. S., Matsumura, S., Htoon, H. M., Tian, J., Lim, S. B., Sensaki, S., … Saw, S. M. (2020). MRI of posterior eye shape and its associations with myopia and ethnicity. Br J Ophthalmol, 104(9), 1239–1245. https://doi.org/10.1136/bjophthalmol-2019-315020
Lim, Laurence Shen, Saiko Matsumura, Hla Myint Htoon, James Tian, Shin Bin Lim, Sonoko Sensaki, Christopher Chen, et al. “MRI of posterior eye shape and its associations with myopia and ethnicity.Br J Ophthalmol 104, no. 9 (September 2020): 1239–45. https://doi.org/10.1136/bjophthalmol-2019-315020.
Lim LS, Matsumura S, Htoon HM, Tian J, Lim SB, Sensaki S, et al. MRI of posterior eye shape and its associations with myopia and ethnicity. Br J Ophthalmol. 2020 Sep;104(9):1239–45.
Lim, Laurence Shen, et al. “MRI of posterior eye shape and its associations with myopia and ethnicity.Br J Ophthalmol, vol. 104, no. 9, Sept. 2020, pp. 1239–45. Pubmed, doi:10.1136/bjophthalmol-2019-315020.
Lim LS, Matsumura S, Htoon HM, Tian J, Lim SB, Sensaki S, Chen C, Hilal S, Wong TY, Cheng CY, Kuo A, Saw SM. MRI of posterior eye shape and its associations with myopia and ethnicity. Br J Ophthalmol. 2020 Sep;104(9):1239–1245.

Published In

Br J Ophthalmol

DOI

EISSN

1468-2079

Publication Date

September 2020

Volume

104

Issue

9

Start / End Page

1239 / 1245

Location

England

Related Subject Headings

  • Vision Tests
  • Singapore
  • Posterior Eye Segment
  • Ophthalmology & Optometry
  • Myopia
  • Middle Aged
  • Male
  • Magnetic Resonance Imaging
  • Humans
  • Female