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Blood flow velocity quantification using splitspectrum amplitude-decorrelation angiography with optical coherence tomography

Publication ,  Journal Article
Tokayer, J; Jia, Y; Dhalla, AH; Huang, D
Published in: Biomedical Optics Express
January 1, 2013

The split-spectrum amplitude-decorrelation angiography (SSADA) algorithm was recently developed as a method for imaging blood flow in the human retina without the use of phase information. In order to enable absolute blood velocity quantification, in vitro phantom experiments are performed to correlate the SSADA signal at multiple time scales with various preset velocities. A linear model relating SSADA measurements to absolute flow velocities is derived using the phantom data. The operating range for the linear model is discussed along with its implication for velocity quantification with SSADA in a clinical setting. © 2013 Optical Society of America.

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Published In

Biomedical Optics Express

DOI

EISSN

2156-7085

Publication Date

January 1, 2013

Volume

4

Issue

10

Start / End Page

1909 / 1924

Related Subject Headings

  • 5102 Atomic, molecular and optical physics
  • 4003 Biomedical engineering
  • 3212 Ophthalmology and optometry
  • 0912 Materials Engineering
  • 0205 Optical Physics
 

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Tokayer, J., Jia, Y., Dhalla, A. H., & Huang, D. (2013). Blood flow velocity quantification using splitspectrum amplitude-decorrelation angiography with optical coherence tomography. Biomedical Optics Express, 4(10), 1909–1924. https://doi.org/10.1364/BOE.4.001909
Tokayer, J., Y. Jia, A. H. Dhalla, and D. Huang. “Blood flow velocity quantification using splitspectrum amplitude-decorrelation angiography with optical coherence tomography.” Biomedical Optics Express 4, no. 10 (January 1, 2013): 1909–24. https://doi.org/10.1364/BOE.4.001909.
Tokayer J, Jia Y, Dhalla AH, Huang D. Blood flow velocity quantification using splitspectrum amplitude-decorrelation angiography with optical coherence tomography. Biomedical Optics Express. 2013 Jan 1;4(10):1909–24.
Tokayer, J., et al. “Blood flow velocity quantification using splitspectrum amplitude-decorrelation angiography with optical coherence tomography.” Biomedical Optics Express, vol. 4, no. 10, Jan. 2013, pp. 1909–24. Scopus, doi:10.1364/BOE.4.001909.
Tokayer J, Jia Y, Dhalla AH, Huang D. Blood flow velocity quantification using splitspectrum amplitude-decorrelation angiography with optical coherence tomography. Biomedical Optics Express. 2013 Jan 1;4(10):1909–1924.
Journal cover image

Published In

Biomedical Optics Express

DOI

EISSN

2156-7085

Publication Date

January 1, 2013

Volume

4

Issue

10

Start / End Page

1909 / 1924

Related Subject Headings

  • 5102 Atomic, molecular and optical physics
  • 4003 Biomedical engineering
  • 3212 Ophthalmology and optometry
  • 0912 Materials Engineering
  • 0205 Optical Physics