Observation of microtubules with scanning force microscopy in liquid
Publication
, Conference
De Pablo, PJ; Schaap, IAT; Schmidt, CF
Published in: Nanotechnology
February 1, 2003
We present the application of scanning force microscopy using the jumping mode to investigate microtubules adsorbed to glass in air and in liquid. To fix the microtubules the glass surfaces were silanized with aminopropyl-triethoxy-silane. The observed structures ranged from disrupted microtubules in air to intact microtubules in liquid. Intact microtubules show heights between 20 and 24 nm confirming the diameter found in electron microscopy studies. The force applied by the tip was critical for the microtubule height, indicating deformation by the tip. Internal structure, corresponding to protofilaments, was found.
Duke Scholars
Published In
Nanotechnology
DOI
ISSN
0957-4484
Publication Date
February 1, 2003
Volume
14
Issue
2
Start / End Page
143 / 146
Related Subject Headings
- Nanoscience & Nanotechnology
Citation
APA
Chicago
ICMJE
MLA
NLM
De Pablo, P. J., Schaap, I. A. T., & Schmidt, C. F. (2003). Observation of microtubules with scanning force microscopy in liquid. In Nanotechnology (Vol. 14, pp. 143–146). https://doi.org/10.1088/0957-4484/14/2/308
De Pablo, P. J., I. A. T. Schaap, and C. F. Schmidt. “Observation of microtubules with scanning force microscopy in liquid.” In Nanotechnology, 14:143–46, 2003. https://doi.org/10.1088/0957-4484/14/2/308.
De Pablo PJ, Schaap IAT, Schmidt CF. Observation of microtubules with scanning force microscopy in liquid. In: Nanotechnology. 2003. p. 143–6.
De Pablo, P. J., et al. “Observation of microtubules with scanning force microscopy in liquid.” Nanotechnology, vol. 14, no. 2, 2003, pp. 143–46. Scopus, doi:10.1088/0957-4484/14/2/308.
De Pablo PJ, Schaap IAT, Schmidt CF. Observation of microtubules with scanning force microscopy in liquid. Nanotechnology. 2003. p. 143–146.
Published In
Nanotechnology
DOI
ISSN
0957-4484
Publication Date
February 1, 2003
Volume
14
Issue
2
Start / End Page
143 / 146
Related Subject Headings
- Nanoscience & Nanotechnology