Christoph F. Schmidt
Hertha Sponer Distinguished Professor of Physics
Current Appointments & Affiliations
- Hertha Sponer Distinguished Professor of Physics, Physics, Trinity College of Arts & Sciences 2018
- Professor of Physics, Physics, Trinity College of Arts & Sciences 2018
- Professor of Biomedical Engineering, Biomedical Engineering, Pratt School of Engineering 2019
- Professor of Biology, Biology, Trinity College of Arts & Sciences 2019
Contact Information
- Box 90305, Durham, NC 27708
- Duke University, Department of Physics, Duke Box 90305, 124 Science Drive, Durham, NC 27708
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christoph.schmidt@duke.edu
(919) 660-2708
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Schmidt lab
- Background
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Education, Training, & Certifications
- D.R., Technical University of Munich (Germany) 1988
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Previous Appointments & Affiliations
- Research Professor of Physics, Physics, Trinity College of Arts & Sciences 2018
- Scholar In Residence of Physics, Physics, Trinity College of Arts & Sciences 2017
- Recognition
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In the News
- Research
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Selected Grants
- Mechanism of epidermal coordination during development and regeneration in zebrafish awarded by National Institutes of Health 2023 - 2028
- University Training Program in Biomolecular and Tissue Engineering awarded by National Institutes of Health 1994 - 2027
- Collaborative Research: Single-molecule in vivo analysis of mechanosensitive channels in bacteria using force spectroscopy awarded by National Science Foundation 2022 - 2025
- Acquisition of a VRS1250 Video-Rate Imaging Module for a Shared-Use Asylum-Cypher Atomic Force Microscope (AFM) awarded by North Carolina Biotechnology Center 2023 - 2024
- LUMICKS C-TRAP awarded by National Institutes of Health 2022 - 2023
- missing activity
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External Relationships
- Agence Nationale de la Recherche, France
- Arizona State University
- European Research Council
- University of Goettingen
- Publications & Artistic Works
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Selected Publications
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Books
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Gittes, F., and C. F. Schmidt. Signals and noise in micromechanical measurements. Vol. 55, 1998. https://doi.org/10.1016/s0091-679x(08)60406-9.Full Text
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Academic Articles
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Haertter, Daniel, Xiaolei Wang, Stephanie M. Fogerson, Nitya Ramkumar, Janice M. Crawford, Kenneth D. Poss, Stefano Di Talia, Daniel P. Kiehart, and Christoph F. Schmidt. “DeepProjection: specific and robust projection of curved 2D tissue sheets from 3D microscopy using deep learning.” Development 149, no. 21 (November 1, 2022). https://doi.org/10.1242/dev.200621.Full Text Link to Item
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Jayachandran, Christina, Arindam Ghosh, Meenakshi Prabhune, Jonathan Bath, Andrew J. Turberfield, Lara Hauke, Jörg Enderlein, Florian Rehfeldt, and Christoph F. Schmidt. “A DNA-based optical force sensor for live-cell applications.” Biorxiv, December 24, 2021.Link to Item
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Haertter, Daniel, Xiaolei Wang, Stephanie M. Fogerson, Nitya Ramkumar, Janice M. Crawford, Kenneth D. Poss, Stefano Di Talia, Daniel P. Kiehart, and Christoph F. Schmidt. “DeepProjection: Rapid and structure-specific projections of tissue sheets embedded in 3D microscopy stacks using deep learning.” Biorxiv, November 17, 2021. https://doi.org/10.1101/2021.11.17.468809.Full Text
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Nishi, Kengo, Fred C. MacKintosh, and Christoph F. Schmidt. “Multiscale Microrheology Using Fluctuating Filaments as Stealth Probes.” Physical Review Letters 127, no. 15 (October 2021): 158001. https://doi.org/10.1103/physrevlett.127.158001.Full Text
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Raja, Sufi O., Alexey I. Chizhik, Christoph F. Schmidt, Jörg Enderlein, and Arindam Ghosh. “Mapping Activity-Dependent Quasi-stationary States of Mitochondrial Membranes with Graphene-Induced Energy Transfer Imaging.” Nano Letters 21, no. 19 (October 2021): 8244–49. https://doi.org/10.1021/acs.nanolett.1c02672.Full Text
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Mizuno, D., C. Tardin, and C. F. Schmidt. “Rapid local compression in active gels is caused by nonlinear network response.” Soft Matter 16, no. 40 (October 2020): 9369–82. https://doi.org/10.1039/c9sm02362c.Full Text Open Access Copy
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Das, Moumita, Christoph F. Schmidt, and Michael Murrell. “Introduction to Active Matter.” Soft Matter 16, no. 31 (August 2020): 7185–90. https://doi.org/10.1039/d0sm90137g.Full Text
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Rabbani, Mohammad T., Christoph F. Schmidt, and Alexandra Ros. “Length-Selective Dielectrophoretic Manipulation of Single-Walled Carbon Nanotubes.” Analytical Chemistry 92, no. 13 (July 2020): 8901–8. https://doi.org/10.1021/acs.analchem.0c00794.Full Text
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Butkevich, E., N. C. Verma, N. Oleksiievets, I. Gregor, C. F. Schmidt, J. Enderlein, C. K. Nandi, and A. I. Chizhik. “Carbon Dots for Studying Muscle Architecture.” Acs Applied Nano Materials 2, no. 12 (December 27, 2019): 7466–72. https://doi.org/10.1021/acsanm.9b01815.Full Text
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Katana, Radoslaw, Chonglin Guan, Damiano Zanini, Matthew E. Larsen, Diego Giraldo, Bart R. H. Geurten, Christoph F. Schmidt, Steven G. Britt, and Martin C. Göpfert. “Chromophore-Independent Roles of Opsin Apoproteins in Drosophila Mechanoreceptors.” Current Biology : Cb 29, no. 17 (September 2019): 2961-2969.e4. https://doi.org/10.1016/j.cub.2019.07.036.Full Text
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Tarantola, Marco, Tim Meyer, Christoph F. Schmidt, and Wolfram-Hubertus Zimmermann. “Physics meets medicine - At the heart of active matter.” Progress in Biophysics and Molecular Biology 144 (July 2019): 1–2. https://doi.org/10.1016/j.pbiomolbio.2019.03.009.Full Text
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Butkevich, Eugenia, Peter Weist, Daniel Härtter, Dieter Klopfenstein, Renata Garces, and Christoph Schmidt. “Drebrin-like protein regulates body bending ofC. elegansvia suppression of NCA cation leak channels,” 2019. https://doi.org/10.1101/2019.12.12.874289.Full Text
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Nishi, Kengo, Maria L. Kilfoil, Christoph F. Schmidt, and F. C. MacKintosh. “Reply to the 'Comment on "A symmetrical method to obtain shear moduli from microrheology"' by M. Tassieri, Soft Matter, 2018, 14, DOI.” Soft Matter 14, no. 42 (October 2018): 8671–72. https://doi.org/10.1039/c8sm01792a.Full Text
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Tassieri, Manlio. “Comment on "A symmetrical method to obtain shear moduli from microrheology" by K. Nishi, M. L. Kilfoil, C. F. Schmidt, and F. C. MacKintosh, Soft Matter, 2018, 14, 3716.” Soft Matter 14, no. 42 (October 2018): 8666–70. https://doi.org/10.1039/c8sm00806j.Full Text
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Tan, Tzer Han, Maya Malik-Garbi, Enas Abu-Shah, Junang Li, Abhinav Sharma, Fred C. MacKintosh, Kinneret Keren, Christoph F. Schmidt, and Nikta Fakhri. “Self-organized stress patterns drive state transitions in actin cortices.” Science Advances 4, no. 6 (June 2018): eaar2847. https://doi.org/10.1126/sciadv.aar2847.Full Text
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Nishi, Kengo, Maria L. Kilfoil, Christoph F. Schmidt, and F. C. MacKintosh. “A symmetrical method to obtain shear moduli from microrheology.” Soft Matter 14, no. 19 (May 2018): 3716–23. https://doi.org/10.1039/c7sm02499a.Full Text
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Heidemann, Knut M., Andrew O. Sageman-Furnas, Abhinav Sharma, Florian Rehfeldt, Christoph F. Schmidt, and Max Wardetzky. “Topology determines force distributions in one-dimensional random spring networks.” Physical Review. E 97, no. 2–1 (February 2018): 022306. https://doi.org/10.1103/physreve.97.022306.Full Text
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Heidemann, Knut M., Andrew O. Sageman-Furnas, Abhinav Sharma, Florian Rehfeldt, Christoph F. Schmidt, and Max Wardetzky. “Topology Counts: Force Distributions in Circular Spring Networks.” Physical Review Letters 120, no. 6 (February 2018): 068001. https://doi.org/10.1103/physrevlett.120.068001.Full Text
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Rezvani, S., N. Shi, T. M. Squires, and C. F. Schmidt. “Microfluidic device for chemical and mechanical manipulation of suspended cells.” Journal of Physics D: Applied Physics 51, no. 4 (January 10, 2018). https://doi.org/10.1088/1361-6463/aaa121.Full Text
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Prahlad, Achintya, Christian Spalthoff, Deqing Kong, Jörg Großhans, Martin C. Göpfert, and Christoph F. Schmidt. “Mechanical Properties of a Drosophila Larval Chordotonal Organ.” Biophysical Journal 113, no. 12 (December 2017): 2796–2804. https://doi.org/10.1016/j.bpj.2017.08.061.Full Text
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Rabbani, Mohammad Towshif, Christoph F. Schmidt, and Alexandra Ros. “Single-Walled Carbon Nanotubes Probed with Insulator-Based Dielectrophoresis.” Analytical Chemistry 89, no. 24 (December 2017): 13235–44. https://doi.org/10.1021/acs.analchem.7b03105.Full Text
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Rehfeldt, F., and C. F. Schmidt. “Physical probing of cells.” Journal of Physics D: Applied Physics 50, no. 46 (October 13, 2017). https://doi.org/10.1088/1361-6463/aa8aa6.Full Text
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Nishizawa, Kenji, Marcel Bremerich, Heev Ayade, Christoph F. Schmidt, Takayuki Ariga, and Daisuke Mizuno. “Feedback-tracking microrheology in living cells.” Science Advances 3, no. 9 (September 2017): e1700318. https://doi.org/10.1126/sciadv.1700318.Full Text
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Gladrow, J., C. P. Broedersz, and C. F. Schmidt. “Nonequilibrium dynamics of probe filaments in actin-myosin networks.” Physical Review. E 96, no. 2–1 (August 2017): 022408. https://doi.org/10.1103/physreve.96.022408.Full Text
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Prabhune, M., F. Rehfeldt, and C. F. Schmidt. “Molecular force sensors to measure stress in cells.” Journal of Physics D: Applied Physics 50, no. 23 (May 15, 2017). https://doi.org/10.1088/1361-6463/aa6e1e.Full Text
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Ghosh, M., S. Ghosh, M. Seibt, I. A. T. Schaap, C. F. Schmidt, and G. Mohan Rao. “Designing deoxidation inhibiting encapsulation of metal oxide nanostructures for fluidic and biological applications.” Applied Surface Science 390 (December 30, 2016): 924–28. https://doi.org/10.1016/j.apsusc.2016.08.117.Full Text
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Butkevich, Eugenia, Wolfgang Härtig, Miroslav Nikolov, Christian Erck, Jens Grosche, Henning Urlaub, Christoph F. Schmidt, Dieter R. Klopfenstein, and John Jia En Chua. “Phosphorylation of FEZ1 by Microtubule Affinity Regulating Kinases regulates its function in presynaptic protein trafficking.” Scientific Reports 6 (June 2016): 26965. https://doi.org/10.1038/srep26965.Full Text
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Gladrow, J., N. Fakhri, F. C. MacKintosh, C. F. Schmidt, and C. P. Broedersz. “Broken Detailed Balance of Filament Dynamics in Active Networks.” Physical Review Letters 116, no. 24 (June 2016): 248301. https://doi.org/10.1103/physrevlett.116.248301.Full Text
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Battle, Christopher, Chase P. Broedersz, Nikta Fakhri, Veikko F. Geyer, Jonathon Howard, Christoph F. Schmidt, and Fred C. MacKintosh. “Broken detailed balance at mesoscopic scales in active biological systems.” Science (New York, N.Y.) 352, no. 6285 (April 2016): 604–7. https://doi.org/10.1126/science.aac8167.Full Text
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Butkevich, Eugenia, Dieter R. Klopfenstein, and Christoph F. Schmidt. “Game of Zones: how actin-binding proteins organize muscle contraction.” Worm 5, no. 2 (April 2016): e1161880. https://doi.org/10.1080/21624054.2016.1161880.Full Text
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Pfeffer, Tobias J., Florenz Sasse, Christoph F. Schmidt, Stefan Lakämper, Andreas Kirschning, and Tim Scholz. “The natural diterpene tonantzitlolone A and its synthetic enantiomer inhibit cell proliferation and kinesin-5 function.” European Journal of Medicinal Chemistry 112 (April 2016): 164–70. https://doi.org/10.1016/j.ejmech.2016.02.022.Full Text
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Chizhik, Anna M., Simon Stein, Mariia O. Dekaliuk, Christopher Battle, Weixing Li, Anja Huss, Mitja Platen, et al. “Super-Resolution Optical Fluctuation Bio-Imaging with Dual-Color Carbon Nanodots.” Nano Letters 16, no. 1 (January 2016): 237–42. https://doi.org/10.1021/acs.nanolett.5b03609.Full Text
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Prabhune, Meenakshi, Kerstin von Roden, Florian Rehfeldt, and Christoph F. Schmidt. “Sulfo-SMCC Prevents Annealing of Taxol-Stabilized Microtubules In Vitro.” Plos One 11, no. 8 (January 2016): e0161623. https://doi.org/10.1371/journal.pone.0161623.Full Text
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Butkevich, Eugenia, Kai Bodensiek, Nikta Fakhri, Kerstin von Roden, Iwan A. T. Schaap, Irina Majoul, Christoph F. Schmidt, and Dieter R. Klopfenstein. “Drebrin-like protein DBN-1 is a sarcomere component that stabilizes actin filaments during muscle contraction.” Nature Communications 6 (July 2015): 7523. https://doi.org/10.1038/ncomms8523.Full Text
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Düselder, André, Vladimir Fridman, Christina Thiede, Alice Wiesbaum, Alina Goldstein, Dieter R. Klopfenstein, Olga Zaitseva, Marcel E. Janson, Larisa Gheber, and Christoph F. Schmidt. “Deletion of the Tail Domain of the Kinesin-5 Cin8 Affects Its Directionality.” The Journal of Biological Chemistry 290, no. 27 (July 2015): 16841–50. https://doi.org/10.1074/jbc.m114.620799.Full Text
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Wilts, Bodo D., Iwan A. T. Schaap, and Christoph F. Schmidt. “Swelling and softening of the cowpea chlorotic mottle virus in response to pH shifts.” Biophysical Journal 108, no. 10 (May 2015): 2541–49. https://doi.org/10.1016/j.bpj.2015.04.019.Full Text
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Wessel, Alok D., Maheshwar Gumalla, Jörg Grosshans, and Christoph F. Schmidt. “The mechanical properties of early Drosophila embryos measured by high-speed video microrheology.” Biophysical Journal 108, no. 8 (April 2015): 1899–1907. https://doi.org/10.1016/j.bpj.2015.02.032.Full Text
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Battle, Christopher, Carolyn M. Ott, Dylan T. Burnette, Jennifer Lippincott-Schwartz, and Christoph F. Schmidt. “Intracellular and extracellular forces drive primary cilia movement.” Proceedings of the National Academy of Sciences of the United States of America 112, no. 5 (February 2015): 1410–15. https://doi.org/10.1073/pnas.1421845112.Full Text
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Schlosser, Florian, Florian Rehfeldt, and Christoph F. Schmidt. “Force fluctuations in three-dimensional suspended fibroblasts.” Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences 370, no. 1661 (February 2015): 20140028. https://doi.org/10.1098/rstb.2014.0028.Full Text
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Kaufeld, T., C. Steinem, and C. F. Schmidt. “Microporous device for local electric recordings on model lipid bilayers.” Journal of Physics D: Applied Physics 48, no. 2 (January 21, 2015). https://doi.org/10.1088/0022-3727/48/2/025401.Full Text
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Heidemann, Knut M., Abhinav Sharma, Florian Rehfeldt, Christoph F. Schmidt, and Max Wardetzky. “Elasticity of 3D networks with rigid filaments and compliant crosslinks.” Soft Matter 11, no. 2 (January 2015): 343–54. https://doi.org/10.1039/c4sm01789g.Full Text
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Fakhri, Nikta, Alok D. Wessel, Charlotte Willms, Matteo Pasquali, Dieter R. Klopfenstein, Frederick C. MacKintosh, and Christoph F. Schmidt. “High-resolution mapping of intracellular fluctuations using carbon nanotubes.” Science (New York, N.Y.) 344, no. 6187 (May 2014): 1031–35. https://doi.org/10.1126/science.1250170.Full Text
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Fakhri, Nikta, and Christoph F. Schmidt. “A surprising twist.” Elife 3 (April 2014): e02715. https://doi.org/10.7554/elife.02715.Full Text
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Atakhorrami, M., G. H. Koenderink, J. F. Palierne, F. C. Mackintosh, and C. F. Schmidt. “Scale-dependent nonaffine elasticity of semiflexible polymer networks.” Physical Review Letters 112, no. 8 (February 24, 2014). https://doi.org/10.1103/PhysRevLett.112.088101.Full Text
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Fridman, Vladimir, Adina Gerson-Gurwitz, Ofer Shapira, Natalia Movshovich, Stefan Lakämper, Christoph F. Schmidt, and Larisa Gheber. “Kinesin-5 Kip1 is a bi-directional motor that stabilizes microtubules and tracks their plus-ends in vivo.” Journal of Cell Science 126, no. Pt 18 (September 2013): 4147–59. https://doi.org/10.1242/jcs.125153.Full Text
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Battle, C., L. Lautscham, and C. F. Schmidt. “Differential interference contrast microscopy using light-emitting diode illumination in conjunction with dual optical traps.” The Review of Scientific Instruments 84, no. 5 (May 2013): 053703. https://doi.org/10.1063/1.4804597.Full Text
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Thiede, Christina, Stefan Lakämper, Alok D. Wessel, Stefanie Kramer, and Christoph F. Schmidt. “A chimeric kinesin-1 head/kinesin-5 tail motor switches between diffusive and processive motility.” Biophysical Journal 104, no. 2 (January 2013): 432–41. https://doi.org/10.1016/j.bpj.2012.11.3810.Full Text
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Düselder, André, Christina Thiede, Christoph F. Schmidt, and Stefan Lakämper. “Neck-linker length dependence of processive Kinesin-5 motility.” Journal of Molecular Biology 423, no. 2 (October 2012): 159–68. https://doi.org/10.1016/j.jmb.2012.06.043.Full Text
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Nijenhuis, Nadja, Daisuke Mizuno, Jos A. E. Spaan, and Christoph F. Schmidt. “High-resolution microrheology in the pericellular matrix of prostate cancer cells.” Journal of the Royal Society, Interface 9, no. 73 (August 2012): 1733–44. https://doi.org/10.1098/rsif.2011.0825.Full Text
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Valdés, Viviana, José Ignacio Valenzuela, Daniela A. Salas, Matías Jaureguiberry-Bravo, Carolina Otero, Christina Thiede, Christoph F. Schmidt, and Andrés Couve. “Endoplasmic reticulum sorting and kinesin-1 command the targeting of axonal GABAB receptors.” Plos One 7, no. 8 (January 2012): e44168. https://doi.org/10.1371/journal.pone.0044168.Full Text
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Gerson-Gurwitz, Adina, Christina Thiede, Natalia Movshovich, Vladimir Fridman, Maria Podolskaya, Tsafi Danieli, Stefan Lakämper, Dieter R. Klopfenstein, Christoph F. Schmidt, and Larisa Gheber. “Directionality of individual kinesin-5 Cin8 motors is modulated by loop 8, ionic strength and microtubule geometry.” The Embo Journal 30, no. 24 (November 2011): 4942–54. https://doi.org/10.1038/emboj.2011.403.Full Text
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Ivanovska, Irena L., Roberto Miranda, Jose L. Carrascosa, Gijs J. L. Wuite, and Christoph F. Schmidt. “Discrete fracture patterns of virus shells reveal mechanical building blocks.” Proceedings of the National Academy of Sciences of the United States of America 108, no. 31 (August 2011): 12611–16. https://doi.org/10.1073/pnas.1105586108.Full Text
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Toyota, T., D. A. Head, C. F. Schmidt, and D. Mizuno. “Non-Gaussian athermal fluctuations in active gels.” Soft Matter 7, no. 7 (May 16, 2011): 3234–39. https://doi.org/10.1039/c0sm00925c.Full Text
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Schaap, Iwan A. T., Carolina Carrasco, Pedro J. de Pablo, and Christoph F. Schmidt. “Kinesin walks the line: single motors observed by atomic force microscopy.” Biophysical Journal 100, no. 10 (May 2011): 2450–56. https://doi.org/10.1016/j.bpj.2011.04.015.Full Text
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Veigel, Claudia, and Christoph F. Schmidt. “Moving into the cell: single-molecule studies of molecular motors in complex environments.” Nature Reviews. Molecular Cell Biology 12, no. 3 (March 2011): 163–76. https://doi.org/10.1038/nrm3062.Full Text
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Butterfield, Anthony E., Russell J. Stewart, Christoph F. Schmidt, and Mikhail Skliar. “Bidirectional power stroke by ncd kinesin.” Biophysical Journal 99, no. 12 (December 2010): 3905–15. https://doi.org/10.1016/j.bpj.2010.10.045.Full Text
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Lakämper, Stefan, Christina Thiede, André Düselder, Stefanie Reiter, Mikhail J. Korneev, Lukas C. Kapitein, Erwin J. G. Peterman, and Christoph F. Schmidt. “The effect of monastrol on the processive motility of a dimeric kinesin-5 head/kinesin-1 stalk chimera.” Journal of Molecular Biology 399, no. 1 (May 2010): 1–8. https://doi.org/10.1016/j.jmb.2010.03.009.Full Text
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Mackintosh, Frederick C., and Christoph F. Schmidt. “Active cellular materials.” Current Opinion in Cell Biology 22, no. 1 (February 2010): 29–35. https://doi.org/10.1016/j.ceb.2010.01.002.Full Text
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Calmat, Stéphane, Johnny Hendriks, Harm van Heerikhuizen, Christoph F. Schmidt, Saskia M. van der Vies, and Erwin J. G. Peterman. “Dissociation kinetics of the GroEL-gp31 chaperonin complex studied with Förster resonance energy transfer.” Biochemistry 48, no. 49 (December 2009): 11692–98. https://doi.org/10.1021/bi9013962.Full Text
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Veigel, Claudia, and Christoph F. Schmidt. “Biochemistry. Friction in motor proteins.” Science (New York, N.Y.) 325, no. 5942 (August 2009): 826–27. https://doi.org/10.1126/science.1178017.Full Text
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Nijenhuis, Nadja, Daisuke Mizuno, Jos A. E. Spaan, and Christoph F. Schmidt. “Viscoelastic response of a model endothelial glycocalyx.” Physical Biology 6, no. 2 (July 2009): 025014. https://doi.org/10.1088/1478-3975/6/2/025014.Full Text
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Mizuno, Daisuke, Rommel Bacabac, Catherine Tardin, David Head, and Christoph F. Schmidt. “High-resolution probing of cellular force transmission.” Physical Review Letters 102, no. 16 (April 2009): 168102. https://doi.org/10.1103/physrevlett.102.168102.Full Text
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Mameren, Joost van, Karen C. Vermeulen, Fred Gittes, and Christoph F. Schmidt. “Leveraging single protein polymers to measure flexural rigidity.” The Journal of Physical Chemistry. B 113, no. 12 (March 2009): 3837–44. https://doi.org/10.1021/jp808328a.Full Text
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Wildenberg, Siet M. J. L. van den, Li Tao, Lukas C. Kapitein, Christoph F. Schmidt, Jonathan M. Scholey, and Erwin J. G. Peterman. “The homotetrameric kinesin-5 KLP61F preferentially crosslinks microtubules into antiparallel orientations.” Current Biology : Cb 18, no. 23 (December 2008): 1860–64. https://doi.org/10.1016/j.cub.2008.10.026.Full Text
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Jabbari-Farouji, S., M. Atakhorrami, D. Mizuno, E. Eiser, G. H. Wegdam, F. C. Mackintosh, Daniel Bonn, and C. F. Schmidt. “High-bandwidth viscoelastic properties of aging colloidal glasses and gels.” Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics 78, no. 6 Pt 1 (December 2008): 061402. https://doi.org/10.1103/physreve.78.061402.Full Text
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Kapitein, Lukas C., Marcel E. Janson, Siet M. J. L. van den Wildenberg, Casper C. Hoogenraad, Christoph F. Schmidt, and Erwin J. G. Peterman. “Microtubule-driven multimerization recruits ase1p onto overlapping microtubules.” Current Biology : Cb 18, no. 21 (November 2008): 1713–17. https://doi.org/10.1016/j.cub.2008.09.046.Full Text
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Mizuno, D., D. A. Head, F. C. MacKintosh, and C. F. Schmidt. “Active and passive microrheology in equilibrium and nonequilibrium systems.” Macromolecules 41, no. 19 (October 14, 2008): 7194–7202. https://doi.org/10.1021/ma801218z.Full Text
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Jabbari-Farouji, S., D. Mizuno, D. Derks, G. H. Wegdam, F. C. MacKintosh, C. F. Schmidt, and D. Bonn. “Effective temperatures from the fluctuation-dissipation measurements in soft glassy materials.” Epl 84, no. 2 (October 1, 2008). https://doi.org/10.1209/0295-5075/84/20006.Full Text
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Nijenhuis, Nadja, Daisuke Mizuno, Christoph F. Schmidt, Hans Vink, and Jos A. E. Spaan. “Microrheology of hyaluronan solutions: implications for the endothelial glycocalyx.” Biomacromolecules 9, no. 9 (September 2008): 2390–98. https://doi.org/10.1021/bm800381z.Full Text
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Bacabac, R. G., D. Mizuno, C. F. Schmidt, F. C. MacKintosh, J. J. W. A. Van Loon, J. Klein-Nulend, and T. H. Smit. “Erratum to "Round versus flat: Bone cell morphology, elasticity, and mechanosensing" [J. Biomech. 41 (2008) 1590-1598] (DOI:10.1016/j.jbiomech.2008.01.031).” Journal of Biomechanics 41, no. 12 (August 28, 2008): 2786. https://doi.org/10.1016/j.jbiomech.2008.01.035.Full Text
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Kapitein, Lukas C., Benjamin H. Kwok, Joshua S. Weinger, Christoph F. Schmidt, Tarun M. Kapoor, and Erwin J. G. Peterman. “Microtubule cross-linking triggers the directional motility of kinesin-5.” The Journal of Cell Biology 182, no. 3 (August 2008): 421–28. https://doi.org/10.1083/jcb.200801145.Full Text
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Walder, Robert, Christoph F. Schmidt, and Michael Dennin. “Combined macro- and microrheometer for use with Langmuir monolayers.” The Review of Scientific Instruments 79, no. 6 (June 2008): 063905. https://doi.org/10.1063/1.2937649.Full Text
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Atakhorrami, M., D. Mizuno, G. H. Koenderink, T. B. Liverpool, F. C. MacKintosh, and C. F. Schmidt. “Short-time inertial response of viscoelastic fluids measured with Brownian motion and with active probes.” Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics 77, no. 6 Pt 1 (June 2008): 061508. https://doi.org/10.1103/physreve.77.061508.Full Text
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Atakhorrami, M., K. M. Addas, and C. F. Schmidt. “Twin optical traps for two-particle cross-correlation measurements: eliminating cross-talk.” The Review of Scientific Instruments 79, no. 4 (April 2008): 043103. https://doi.org/10.1063/1.2898407.Full Text
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Bacabac, Rommel G., Daisuke Mizuno, Christoph F. Schmidt, Fred C. MacKintosh, Jack J. W. A. Van Loon, Jenneke Klein-Nulend, and Theo H. Smit. “Round versus flat: bone cell morphology, elasticity, and mechanosensing.” Journal of Biomechanics 41, no. 7 (January 2008): 1590–98. https://doi.org/10.1016/j.jbiomech.2008.01.031.Full Text
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Korneev, Mikhail J., Stefan Lakämper, and Christoph F. Schmidt. “Load-dependent release limits the processive stepping of the tetrameric Eg5 motor.” European Biophysics Journal : Ebj 36, no. 6 (July 2007): 675–81. https://doi.org/10.1007/s00249-007-0134-6.Full Text
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Schaap, Iwan A. T., Bernd Hoffmann, Carolina Carrasco, Rudolf Merkel, and Christoph F. Schmidt. “Tau protein binding forms a 1 nm thick layer along protofilaments without affecting the radial elasticity of microtubules.” Journal of Structural Biology 158, no. 3 (June 2007): 282–92. https://doi.org/10.1016/j.jsb.2006.11.010.Full Text
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Jabbari-Farouji, Sara, Daisuke Mizuno, Maryam Atakhorrami, Fred C. MacKintosh, Christoph F. Schmidt, Erika Eiser, Gerard H. Wegdam, and Daniel Bonn. “Fluctuation-dissipation theorem in an aging colloidal glass.” Physical Review Letters 98, no. 10 (March 2007): 108302. https://doi.org/10.1103/physrevlett.98.108302.Full Text
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Mizuno, Daisuke, Catherine Tardin, C. F. Schmidt, and F. C. Mackintosh. “Nonequilibrium mechanics of active cytoskeletal networks.” Science (New York, N.Y.) 315, no. 5810 (January 2007): 370–73. https://doi.org/10.1126/science.1134404.Full Text
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Klug, William S., Robijn F. Bruinsma, Jean-Philippe Michel, Charles M. Knobler, Irena L. Ivanovska, Christoph F. Schmidt, and Gijs J. L. Wuite. “Failure of viral shells.” Physical Review Letters 97, no. 22 (December 2006): 228101. https://doi.org/10.1103/physrevlett.97.228101.Full Text
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Vatsa, Aviral, Daisuke Mizuno, Theo H. Smit, Christoph F. Schmidt, Fred C. MacKintosh, and Jenneke Klein-Nulend. “Bio imaging of intracellular NO production in single bone cells after mechanical stimulation.” Journal of Bone and Mineral Research : The Official Journal of the American Society for Bone and Mineral Research 21, no. 11 (November 2006): 1722–28. https://doi.org/10.1359/jbmr.060720.Full Text
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Kwok, Benjamin H., Lukas C. Kapitein, Jeffrey H. Kim, Erwin J. G. Peterman, Christoph F. Schmidt, and Tarun M. Kapoor. “Allosteric inhibition of kinesin-5 modulates its processive directional motility.” Nature Chemical Biology 2, no. 9 (September 2006): 480–85. https://doi.org/10.1038/nchembio812.Full Text
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Schaap, Iwan A. T., Carolina Carrasco, Pedro J. de Pablo, Frederick C. MacKintosh, and Christoph F. Schmidt. “Elastic response, buckling, and instability of microtubules under radial indentation.” Biophysical Journal 91, no. 4 (August 2006): 1521–31. https://doi.org/10.1529/biophysj.105.077826.Full Text
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Berg-Sørensen, K., E. J. G. Peterman, T. Weber, C. F. Schmidt, and H. Flyvbjerg. “Power spectrum analysis for optical tweezers. II: Laser wavelength dependence of parasitic filtering, and how to achieve high bandwidth.” Review of Scientific Instruments 77, no. 6 (July 11, 2006). https://doi.org/10.1063/1.2204589.Full Text
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Atakhorrami, M., J. I. Sulkowska, K. M. Addas, G. H. Koenderink, J. X. Tang, A. J. Levine, F. C. Mackintosh, and C. F. Schmidt. “Correlated fluctuations of microparticles in viscoelastic solutions: quantitative measurement of material properties by microrheology in the presence of optical traps.” Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics 73, no. 6 Pt 1 (June 2006): 061501. https://doi.org/10.1103/physreve.73.061501.Full Text
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Graveland-Bikker, J. F., I. A. T. Schaap, C. F. Schmidt, and C. G. de Kruif. “Structural and mechanical study of a self-assembling protein nanotube.” Nano Letters 6, no. 4 (April 2006): 616–21. https://doi.org/10.1021/nl052205h.Full Text
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Koenderink, G. H., M. Atakhorrami, F. C. MacKintosh, and C. F. Schmidt. “High-frequency stress relaxation in semiflexible polymer solutions and networks.” Physical Review Letters 96, no. 13 (April 2006): 138307. https://doi.org/10.1103/physrevlett.96.138307.Full Text
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Michel, J. P., I. L. Ivanovska, M. M. Gibbons, W. S. Klug, C. M. Knobler, G. J. L. Wuite, and C. F. Schmidt. “Nanoindentation studies of full and empty viral capsids and the effects of capsid protein mutations on elasticity and strength.” Proceedings of the National Academy of Sciences of the United States of America 103, no. 16 (April 2006): 6184–89. https://doi.org/10.1073/pnas.0601744103.Full Text
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Vermeulen, Karen C., Gijs J. L. Wuite, Ger J. M. Stienen, and Christoph F. Schmidt. “Optical trap stiffness in the presence and absence of spherical aberrations.” Applied Optics 45, no. 8 (March 2006): 1812–19. https://doi.org/10.1364/ao.45.001812.Full Text
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Vermeulen, K. C., J. Van Mameren, G. J. M. Stienen, E. J. G. Peterman, G. J. L. Wuite, and C. F. Schmidt. “Calibrating bead displacements in optical tweezers using acousto-optic deflectors.” Review of Scientific Instruments 77, no. 1 (February 6, 2006): 1–6. https://doi.org/10.1063/1.2165568.Full Text
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Goodman, R. P., I. A. T. Schaap, C. F. Tardin, C. M. Erben, R. M. Berry, C. F. Schmidt, and A. J. Turberfield. “Rapid chiral assembly of rigid DNA building blocks for molecular nanofabrication.” Science (New York, N.Y.) 310, no. 5754 (December 2005): 1661–65. https://doi.org/10.1126/science.1120367.Full Text
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Atakhorrami, M., G. H. Koenderink, C. F. Schmidt, and F. C. MacKintosh. “Short-time inertial response of viscoelastic fluids: observation of vortex propagation.” Physical Review Letters 95, no. 20 (November 2005): 208302. https://doi.org/10.1103/physrevlett.95.208302.Full Text
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Buchanan, M., M. Atakhorrami, J. F. Palierne, and C. F. Schmidt. “Comparing macrorheology and one- and two-point microrheology in wormlike micelle solutions.” Macromolecules 38, no. 21 (October 18, 2005): 8840–44. https://doi.org/10.1021/ma0500990.Full Text
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Buchanan, M., M. Atakhorrami, J. F. Palierne, F. C. MacKintosh, and C. F. Schmidt. “High-frequency microrheology of wormlike micelles.” Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics 72, no. 1 Pt 1 (July 2005): 011504. https://doi.org/10.1103/physreve.72.011504.Full Text
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Kapitein, Lukas C., Erwin J. G. Peterman, Benjamin H. Kwok, Jeffrey H. Kim, Tarun M. Kapoor, and Christoph F. Schmidt. “The bipolar mitotic kinesin Eg5 moves on both microtubules that it crosslinks.” Nature 435, no. 7038 (May 2005): 114–18. https://doi.org/10.1038/nature03503.Full Text
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Schaap, Iwan A. T., Pedro J. de Pablo, and Christoph F. Schmidt. “Resolving the molecular structure of microtubules under physiological conditions with scanning force microscopy.” European Biophysics Journal : Ebj 33, no. 5 (August 2004): 462–67. https://doi.org/10.1007/s00249-003-0386-8.Full Text
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Addas, Karim M., Christoph F. Schmidt, and Jay X. Tang. “Microrheology of solutions of semiflexible biopolymer filaments using laser tweezers interferometry.” Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics 70, no. 2 Pt 1 (August 2004): 021503. https://doi.org/10.1103/physreve.70.021503.Full Text
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Dijk, Meindert A van, Lukas C. Kapitein, Joost van Mameren, Christoph F. Schmidt, and Erwin J. G. Peterman. “Combining optical trapping and single-molecule fluorescence spectroscopy: enhanced photobleaching of fluorophores.” The Journal of Physical Chemistry. B 108, no. 20 (May 2004): 6479–84. https://doi.org/10.1021/jp049805+.Full Text
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Ivanovska, I. L., P. J. de Pablo, B. Ibarra, G. Sgalari, F. C. MacKintosh, J. L. Carrascosa, C. F. Schmidt, and G. J. L. Wuite. “Bacteriophage capsids: tough nanoshells with complex elastic properties.” Proceedings of the National Academy of Sciences of the United States of America 101, no. 20 (May 2004): 7600–7605. https://doi.org/10.1073/pnas.0308198101.Full Text
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Pablo, P. J. de, I. A. Schaap, F. C. MacKintosh, and C. F. Schmidt. “Deformation and collapse of microtubules on the nanometer scale.” Physical Review Letters 91, no. 9 (August 2003): 098101. https://doi.org/10.1103/physrevlett.91.098101.Full Text
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Peterman, E. J. G., M. A. Van Dijk, L. C. Kapitein, and C. F. Schmidt. “Extending the bandwidth of optical-tweezers interferometry.” Review of Scientific Instruments 74, no. 7 (July 1, 2003): 3246–49. https://doi.org/10.1063/1.1584085.Full Text
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Peterman, Erwin J. G., Frederick Gittes, and Christoph F. Schmidt. “Laser-induced heating in optical traps.” Biophysical Journal 84, no. 2 Pt 1 (February 2003): 1308–16. https://doi.org/10.1016/s0006-3495(03)74946-7.Full Text
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Agayan, Rodney R., Frederick Gittes, Raoul Kopelman, and Christoph F. Schmidt. “Optical trapping near resonance absorption.” Applied Optics 41, no. 12 (April 2002): 2318–27. https://doi.org/10.1364/ao.41.002318.Full Text
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Addas, K. M., A. J. Levine, J. X. Tang, and C. F. Schmidt. “One- and two-particle microrheology in entangled solutions of fd virus.” Materials Research Society Symposium Proceedings 711 (January 1, 2002): 59–65.
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Vermeulen, Karen C., Ger J. M. Stienen, and Christoph F. Schmid. “Cooperative behavior of molecular motors.” Journal of Muscle Research and Cell Motility 23, no. 1 (January 2002): 71–79. https://doi.org/10.1023/a:1019980613619.Full Text
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Chen, C. M., C. F. Schmidt, P. D. Olmsted, and F. C. MacKintosh. “Instability of myelin tubes under dehydration: deswelling of layered cylindrical structures.” Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics 64, no. 5 Pt 1 (November 2001): 050903. https://doi.org/10.1103/physreve.64.050903.Full Text
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deCastro, M. J., R. M. Fondecave, L. A. Clarke, C. F. Schmidt, and R. J. Stewart. “Working strokes by single molecules of the kinesin-related microtubule motor ncd.” Nature Cell Biology 2, no. 10 (October 2000): 724–29. https://doi.org/10.1038/35036357.Full Text
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Kacher, C. M., I. M. Weiss, R. J. Stewart, C. F. Schmidt, P. K. Hansma, M. Radmacher, and M. Fritz. “Imaging microtubules and kinesin decorated microtubules using tapping mode atomic force microscopy in fluids.” European Biophysics Journal : Ebj 28, no. 8 (January 2000): 611–20. https://doi.org/10.1007/s002490050001.Full Text
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MacKintosh, F. C., and C. F. Schmidt. “Microrheology.” Current Opinion in Colloid and Interface Science 4, no. 4 (August 1, 1999): 300–307. https://doi.org/10.1016/S1359-0294(99)90010-9.Full Text
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Allersma, M. W., F. Gittes, M. J. deCastro, R. J. Stewart, and C. F. Schmidt. “Two-dimensional tracking of ncd motility by back focal plane interferometry.” Biophysical Journal 74, no. 2 Pt 1 (February 1998): 1074–85. https://doi.org/10.1016/s0006-3495(98)74031-7.Full Text
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Gittes, F., and C. F. Schmidt. “Thermal noise limitations on micromechanical experiments.” European Biophysics Journal 27, no. 1 (January 1, 1998): 75–81. https://doi.org/10.1007/s002490050113.Full Text
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Gittes, F., and C. F. Schmidt. “Interference model for back-focal-plane displacement detection in optical tweezers.” Optics Letters 23, no. 1 (January 1998): 7–9. https://doi.org/10.1364/ol.23.000007.Full Text
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Stewart, R. J., J. Semerjian, and C. F. Schmidt. “Highly processive motility is not a general feature of the kinesins.” European Biophysics Journal : Ebj 27, no. 4 (January 1998): 353–60. https://doi.org/10.1007/s002490050142.Full Text
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Schnurr, B., F. Gittes, F. C. MacKintosh, and C. F. Schmidt. “Determining microscopic viscoelasticity in flexible and semiflexible polymer networks from thermal fluctuations.” Macromolecules 30, no. 25 (December 15, 1997): 7781–92. https://doi.org/10.1021/ma970555n.Full Text
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Gittes, F., B. Schnurr, P. D. Olmsted, F. C. MacKintosh, and C. F. Schmidt. “Microscopic viscoelasticity: Shear moduli of soft materials determined from thermal fluctuations.” Physical Review Letters 79, no. 17 (January 1, 1997): 3286–89. https://doi.org/10.1103/PhysRevLett.79.3286.Full Text
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Thomson, N. H., M. Fritz, M. Radmacher, J. P. Cleveland, C. F. Schmidt, and P. K. Hansma. “Protein tracking and detection of protein motion using atomic force microscopy.” Biophysical Journal 70, no. 5 (May 1996): 2421–31. https://doi.org/10.1016/s0006-3495(96)79812-0.Full Text
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Gittes, F., and C. F. Schmidt. “Microscopic approaches to dynamics and structure of biological motors.” Current Opinion in Solid State and Materials Science 1, no. 3 (January 1, 1996): 412–24. https://doi.org/10.1016/S1359-0286(96)80034-9.Full Text
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Fritz, M., M. Radmacher, J. P. Cleveland, M. W. Allersma, R. J. Stewart, R. Gieselmann, P. Janmey, C. F. Schmidt, and P. K. Hansma. “Imaging Globular and Filamentous Proteins in Physiological Buffer Solutions with Tapping Mode Atomic Force Microscopy.” Langmuir 11, no. 9 (September 1, 1995): 3529–35. https://doi.org/10.1021/la00009a040.Full Text
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Svoboda, K., C. F. Schmidt, B. J. Schnapp, and S. M. Block. “Direct observation of kinesin stepping by optical trapping interferometry.” Nature 365, no. 6448 (October 1993): 721–27. https://doi.org/10.1038/365721a0.Full Text
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Schmidt, C. F., K. Svoboda, N. Lei, I. B. Petsche, L. E. Berman, C. R. Safinya, and G. S. Grest. “Existence of a flat phase in red cell membrane skeletons.” Science (New York, N.Y.) 259, no. 5097 (February 1993): 952–55. https://doi.org/10.1126/science.8438153.Full Text
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Svoboda, K., C. F. Schmidt, D. Branton, and S. M. Block. “Conformation and elasticity of the isolated red blood cell membrane skeleton.” Biophysical Journal 63, no. 3 (September 1992): 784–93. https://doi.org/10.1016/s0006-3495(92)81644-2.Full Text
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Zimmermann, R. M., C. F. Schmidt, and H. E. Gaub. “Absolute quantities and equilibrium kinetics of macromolecular adsorption measured by fluorescence photobleaching in total internal reflection.” Journal of Colloid and Interface Science 139, no. 1 (October 1, 1990): 268–80. https://doi.org/10.1016/0021-9797(90)90462-W.Full Text
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Schmidt, C. F., R. M. Zimmermann, and H. E. Gaub. “Multilayer adsorption of lysozyme on a hydrophobic substrate.” Biophysical Journal 57, no. 3 (March 1990): 577–88. https://doi.org/10.1016/s0006-3495(90)82573-x.Full Text
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Schmidt, C. F., M. Bärmann, G. Isenberg, and E. Sackmann. “Chain Dynamics, Mesh Size, and Diffusive Transport in Networks of Polymerized Actin: A Quasielastic Light Scattering and Microfluorescence Study.” Macromolecules 22, no. 9 (September 1, 1989): 3638–49. https://doi.org/10.1021/ma00199a023.Full Text
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Bayerl, T. M., C. F. Schmidt, and E. Sackmann. “Kinetics of Symmetric and Asymmetric Phospholipid Transfer between Small Sonicated Vesicles Studied by High-Sensitivity Differential Scanning Calorimetry, NMR, Electron Microscopy, and Dynamic Light Scattering.” Biochemistry 27, no. 16 (August 1, 1988): 6078–85. https://doi.org/10.1021/bi00416a037.Full Text
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Book Sections
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Schmidt, C. F. “A practical guide to optical tweezers.” In Soft Condensed Matter Physics in Molecular and Cell Biology, 259–74, 2006.
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Conference Papers
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Nishi, Kengo, Sufi Raja, An Pham, Fred C. MacKintosh, and Christoph F. Schmidt. “Non-equilibrium fluctuations in cells report on driving forces and organelle mechanics.” In Biorheology, 58:158–158, 2021.Link to Item
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Ranaivosod, Fanomezana M., Amna Abdalla Mohammed Khalid, Steven Rosenfeld, Christoph F. Schmidt, and Anne M. Houdusse. “The Mitotic Kinesin-6 KIF20A is an Unconventional Transporter and Network Builder.” In Biophysical Journal, 120:289A-289A, 2021.Link to Item
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Rabbani, M. T., C. F. Schmidt, and A. Ros. “Towards separation of single walled carbon nanotubes with insulator-based dielectrophoresis.” In 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, Microtas 2017, 1342–43, 2020.
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Keren, K., N. Fakhri, M. Malik-Garbi, E. Abu Shah, and C. F. Schmidt. “Characterization of the mechanical properties of reconstituted contractile actin networks using single wall carbon nanotubes.” In Molecular Biology of the Cell, Vol. 25. AMER SOC CELL BIOLOGY, 2014.Link to Item
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Ott, C. M., C. Battle, J. Lippincott-Schwartz, and C. F. Schmidt. “Primary cilia bend and pivot in response to intracellular and extracellular forces.” In Molecular Biology of the Cell, Vol. 25. AMER SOC CELL BIOLOGY, 2014.Link to Item
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Gurwitz, Adina Gerson, Christina Thiede, Natalia Movshovich, Vladimir Fridman, Maria Podolskaya, Stefan Lakaemper, Dieter R. Klopfenstein, Christoph F. Schmidt, and Larisa Gheber. “Loop 8 Plays a Role in Controlling S. Cerevisiae Kinesin-5 Cin8 Motility and Function.” In Biophysical Journal, 102:702A-702A. CELL PRESS, 2012.Link to Item
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Lakaemper, S., C. Thiede, A. D. Wessel, and C. F. Schmidt. “Exaggerating the switch - a chimeric Kinesin-tetramer with fulsome motile features.” In Molecular Biology of the Cell, Vol. 23. AMER SOC CELL BIOLOGY, 2012.Link to Item
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Gerson-Gurwitz, Adina, Christina Thiede, Natalia Movshovich, Vladimir Fridman, Maria Podolskaya, Stefan Lakämper, Dieter R. Klopfenstein, Christoph F. Schmidt, and Larisa Gheber. “Control of Directionality of Individual Kinesin-5 Motors.” In Biophysical Journal, 102:696a-696a. Elsevier BV, 2012. https://doi.org/10.1016/j.bpj.2011.11.3778.Full Text
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Fakhri, Nikta, Joerg Enderlein, Matteo Pasquali, Frederick C. MacKintosh, and Christoph F. Schmidt. “Carbon nanotubes as mechanical probes of equilibrium and non-equilibrium cytoskeletal networks.” In European Biophysics Journal With Biophysics Letters, 40:159–159. SPRINGER, 2011.Link to Item
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Gerson-Gurwitz, Adina, Christina Thiede, Natalia Movshovich, Vladimir Fridman, Maria Podolskaya, Tsafi Danieli, Stefan Lakaemper, Dieter R. Klopfenstein, Christoph F. Schmidt, and Larisa Gheber. “Control of the fast, slow and reverse gear of the yeast mitotic kinesin-5 Cin8.” In European Biophysics Journal With Biophysics Letters, 40:163–163. SPRINGER, 2011.Link to Item
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Henschel, Volker, Alessandro Esposito, Eugenia Butkevich, Christoph F. Schmidt, Fred S. Wouters, and Dieter R. Klopfenstein. “Detecting protein conformational states in C. elegans in vivo by confocal fluorescence anisotropy.” In European Biophysics Journal With Biophysics Letters, 40:150–150. SPRINGER, 2011.Link to Item
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Thiede, Christina, Adina Gerson-Gurwitz, Natalia Movshovich, Vladimir Fridman, Maria Podolskaya, Tsafi Danieli, Stefan Lakaemper, Dieter Kopfenstein, Christoph F. Schmidt, and Larisa Gheber. “Directionality of the yeast Kinesin-5 Cin8 is controlled by molecular structure and salt conditions.” In European Biophysics Journal With Biophysics Letters, 40:135–135. SPRINGER, 2011.Link to Item
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Dueselder, Andre, Christina Thiede, Stefanie Kramer, Christoph F. Schmidt, and Stefan Lakaemper. “Neck-Linker-Length Dependence of Processive Kinesin-5 Motility.” In Biophysical Journal, 100:122–23. CELL PRESS, 2011.Link to Item
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Fridman, Vladimir, Adina Gerson-Gurwitz, Christina Thiede, Maria Podolskaya, Movshovich Natalia, Stefan Lakamper, Christoph F. Schmidt, and Larisa Gheber. “Mitotic Functions and Motile Properties of the S. cerevisiae Kinesin-5 motors.” In Biophysical Journal, 100:530–530. CELL PRESS, 2011.Link to Item
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Kleeblatt, Jan, Iwan A. T. Schaap, and Christoph F. Schmidt. “A Structural Bistability in the Microtubule Lattice Revealed by AFM Imaging of the Inside of Microtubules.” In Biophysical Journal, 100:449–449. CELL PRESS, 2011.Link to Item
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Mizuno, D., D. Head, F. C. MacKintosh, and C. F. Schmidt. “Motor-driven force fluctuations in suspended cells and in cytoskeletal model systems.” In Molecular Biology of the Cell, Vol. 22. AMER SOC CELL BIOLOGY, 2011.Link to Item
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Zoergiebel, Felix, Marcel Bremerich, Frederick C. MacKintosh, and Christoph F. Schmidt. “Stiff-Filament Microrheology.” In Biophysical Journal, 98:557A-557A. CELL PRESS, 2010.Link to Item
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Thiede, Christina, Stefan Lakämper, Alok D. Weßel, Stefanie Reiter, and Christoph F. Schmidt. “Tetrameric Chimera DK4mer is a Tool to Study Mechanisms Of Kinesin-5 Regulation. A Tetrameric Chimera of a Kinesin 1 and a Kinesin 5 is a Fast Microtubule Sliding Motor.” In Biophysical Journal, 98:165a-165a. Elsevier BV, 2010. https://doi.org/10.1016/j.bpj.2009.12.892.Full Text
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Wilts, Bodo D., Iwan A. T. Schaap, Mark J. Young, Trevor Douglas, Charles M. Knobler, and Christoph F. Schmidt. “Swelling and Softening of the CCMV Plant Virus Capsid in Response to pH Shifts.” In Biophysical Journal, 98:656a-656a. Elsevier BV, 2010. https://doi.org/10.1016/j.bpj.2009.12.3597.Full Text
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Mizunu, D., M. Atakhorrami, K. M. Addas, J. X. Tang, G. H. Koenderink, F. C. MacKintosht, and C. F. Schmidt. “Laser trapping and laser interferometry for high-bandwidth micromechanical probing of biomaterials.” In 2008 Asia Optical Fiber Communication and Optoelectronic Exposition and Conference, Aoe 2008, 2008.
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Mizuno, D., M. Atakhorrami, K. M. Addas, J. X. Tang, G. H. Koenderink, F. C. MacKintosh, and C. F. Schmidt. “Laser trapping and laser interferometry for high-bandwidth micromechanical probing of biomaterials.” In Optics Infobase Conference Papers, 2008.
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Mizuno, D., M. Atakhorrami, K. M. Addas, J. X. Tang, G. H. Koenderink, F. C. MacKintosh, and C. F. Schmidt. “Laser trapping and laser interferometry for high-bandwidth micromechanical probing of biomaterials.” In Optics Infobase Conference Papers, 2008. https://doi.org/10.1364/aoe.2008.sap1.Full Text
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Schmidt, C. F., and D. Mizuno. “Linear and nonlinear laser-trapping microrheology.” In Proceedings of Spie the International Society for Optical Engineering, Vol. 6644, 2007. https://doi.org/10.1117/12.739441.Full Text
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Lakmper, S., M. J. Korneev, S. Reiter, L. C. Kapitein, E. J. G. Peterman, and C. F. Schmidt. “Monastrol-inhibition of a highly processive Kinesin5-head/Kinesin1-stalk chimera.” In European Journal of Cell Biology, 86:9–9. ELSEVIER GMBH, URBAN & FISCHER VERLAG, 2007.Link to Item
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Bacabac, R. G., D. Mizuno, C. F. Schmidt, F. C. MacKintosh, J. J. W. A. Van Loon, J. Klein-Nulend, and T. H. Smit. “Mechanosensitivity and elasticity of bone cells under round and flat morphologies.” In Calcified Tissue International, 80:S72–S72. SPRINGER, 2007.Link to Item
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Bacabac, R. G., D. Mizuno, C. F. Schmidt, F. C. MacKintosh, T. H. Smit, J. J. W. A. Van Loon, and J. Klein-Nulend. “Viscoelasticity and force traction of bone cells in 3-dimensional morphology.” In Calcified Tissue International, 80:S72–S72. SPRINGER, 2007.Link to Item
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Ivanovska, Irena L., Xabier Agirrezabala, Jose L. Carrascosa, Christoph F. Schmidt, and Gijs J. L. Wuite. “Deconstructing viral capsids reveals their strengths and weaknesses.” In Biophysical Journal, 49A-49A. CELL PRESS, 2007.Link to Item
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Kapitein, Lukas C., Benjamin H. Kwok, Christoph F. Schmidt, Tarun M. Kapoor, and Erwin J. G. Peterman. “Microtubule crosslinking triggers the directional motility of Kinesin-5.” In Biophysical Journal, 494A-494A. BIOPHYSICAL SOCIETY, 2007.Link to Item
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Klug, William S., Robijn F. Bruinsma, Jean-Philippe Michel, Charles M. Knobler, Irena L. Ivanovska, Christoph F. Schmidt, and Gijs J. L. Wuite. “Mechanical failure of viral shells.” In Biophysical Journal, 532A-532A. BIOPHYSICAL SOCIETY, 2007.Link to Item
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Lakaemper, Stefan, Mikhail Korneev, and Christoph F. Schmidt. “The effect of monastrol on the biophysical behavior of EG5/DMKHC chimeras.” In Biophysical Journal, 485A-485A. BIOPHYSICAL SOCIETY, 2007.Link to Item
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Schaap, Iwan A. T., Carolina Carrasco, Simone Harder, Bernd Hoffmann, Pedro J. De Pablo, and Christoph F. Schmidt. “Cytoskeletal filaments and their associated proteins studied with atomic force microscopy.” In Biophysical Journal, 309A-309A. BIOPHYSICAL SOCIETY, 2007.Link to Item
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Vatsa, A., D. Mizuno, T. H. Smit, C. F. Schmidt, F. C. MacKintosh, and J. Klein-Nulend. “The mechanosensitive part of a single osteocyte, cell body or cell process?” In Calcified Tissue International, 80:S87–88. SPRINGER, 2007.Link to Item
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Atakhorrami, M., and C. F. Schmidt. “High-bandwidth one-and two-particle microrheology in solutions of wormlike micelles.” In Rheologica Acta, 45:449–56, 2006. https://doi.org/10.1007/s00397-005-0071-1.Full Text
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Ivanovska, I. L., J. P. Michel, G. J. L. Wuite, C. M. Knobler, C. F. Schmidt, and W. M. Gelbart. “Squeezing self-assembled nanocontainers: AFM indentation studies of viral capsids.” In Abstracts of Papers of the American Chemical Society, 229:U709–U709. AMER CHEMICAL SOC, 2005.Link to Item
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Atakhorrami, M., G. H. Koenderink, C. F. Schmidt, and F. C. MacKintosh. “Mapping vortex diffusion in viscous and viscoelastic fluids.” In Biophysical Journal, 88:518A-518A. BIOPHYSICAL SOCIETY, 2005.Link to Item
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Ivanovska, I. L., J. P. Michel, W. M. Gelbart, C. M. Knobler, C. F. Schmidt, and G. J. L. Wuite. “Squeezing CCMV: AFM nanoindentation studies of viruses.” In Biophysical Journal, 88:230A-230A. BIOPHYSICAL SOCIETY, 2005.Link to Item
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Ivanovska, I. L., R. Serrano, J. L. Carrascosa, C. F. Schmidt, and G. J. L. Wuite. “Breaking and buckling viral shells with AFM: Highly ordered structures display complex mechanical properties.” In Biophysical Journal, 88:230A-231A. BIOPHYSICAL SOCIETY, 2005.Link to Item
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Kapitein, L. C., E. J. G. Peterman, B. H. Kwok, J. H. Kim, T. M. Kapoor, and C. F. Schmidt. “The mitotic motor Eg5 slides anti-parallel microtubules apart.” In Biophysical Journal, 88:647A-648A. BIOPHYSICAL SOCIETY, 2005.Link to Item
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Mizuno, D., A. Vatsa, J. Klein-Nulend, T. H. Smit, F. C. MacKintosh, and C. F. Schmidt. “Single-cell nitric oxide detection in mechanosensitive osteocytes.” In Biophysical Journal, 88:432A-432A. BIOPHYSICAL SOCIETY, 2005.Link to Item
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Vermeulen, K. C., J. van Mameren, G. J. L. Wuite, and C. F. Schmidt. “Dependence of optical trap stiffness on focusing depth in the presence and absence of spherical aberrations.” In Biophysical Journal, 88:663A-663A. BIOPHYSICAL SOCIETY, 2005.Link to Item
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Berg-Sørensen, K., E. J. G. Peterman, L. Oddershede, M. Van Dijk, E. L. Florin, C. F. Schmidt, and H. Flyvbjerg. “Parasitic filtering in position detection systems for optical tweezers.” In Proceedings of Spie the International Society for Optical Engineering, 5514:419–27, 2004. https://doi.org/10.1117/12.559582.Full Text
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Peterman, E. J. G., M. A. van Dijk, L. C. Kapitein, J. van Mameren, and C. F. Schmidt. “Minimizing photobleaching in experiments combining optical tweezers and single-molecule fluorescence.” In Abstracts of Papers of the American Chemical Society, 228:U215–U215. AMER CHEMICAL SOC, 2004.Link to Item
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Atakhorrami, M., J. Kwiecinska, K. M. Addas, G. Koenderink, A. J. Levine, J. X. Tang, and C. F. Schmidt. “Cross talk, trapping effects and solvent inertia in one- and two-particle microrheology.” In Biophysical Journal, 86:487A-487A. BIOPHYSICAL SOCIETY, 2004.Link to Item
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Atakhorrami, M., K. M. Addas, M. Buchanan, J. F. Palierne, J. X. Tang, F. C. MacKintosh, and C. F. Schmidt. “Under what conditions do one- and two-particle microrheology report bulk viscoelastic properties?” In Biophysical Journal, 86:487A-487A. BIOPHYSICAL SOCIETY, 2004.Link to Item
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Ivanovska, I., P. J. Pablo, G. Sgalari, F. C. Mackintosh, J. L. Carrascosa, C. F. Schmidt, and G. J. Wuite. “Exploring the nano-mechanics of single virus shells using scanning force microscopy.” In Biophysical Journal, 86:153A-154A. BIOPHYSICAL SOCIETY, 2004.Link to Item
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Koenderink, G. H., M. Atakhorrami, F. C. MacKintosh, and C. F. Schmidt. “One and two particle microrheology of entangled actin solutions.” In Biophysical Journal, 86:360A-360A. BIOPHYSICAL SOCIETY, 2004.Link to Item
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Van Dijk, M. A., J. van Mameren, L. C. Kapitein, C. F. Schmidt, and E. J. G. Peterman. “Minimizing photobleaching in experiments combining optical tweezers and single-molecule fluorescence.” In Biophysical Journal, 86:599A-599A. BIOPHYSICAL SOCIETY, 2004.Link to Item
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Addas, K., J. Tang, C. F. Schmidt, and A. L. Levine. “One- and two-particle microrheology of solutions of semiflexible filamentous fd virus.” In Biophysical Journal, 84:286A-286A. BIOPHYSICAL SOCIETY, 2003.Link to Item
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Broek, B. van den, C. F. Schmidt, and G. J. L. Wuite. “The effect of DNA tension on restriction-enzyme cutting rates studied with optical tweezers.” In Biophysical Journal, 84:141A-141A. BIOPHYSICAL SOCIETY, 2003.Link to Item
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De Pablo, P. J., I. A. T. Schaap, and C. F. Schmidt. “Observation of microtubules with scanning force microscopy in liquid.” In Nanotechnology, 14:143–46, 2003. https://doi.org/10.1088/0957-4484/14/2/308.Full Text
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Kapitein, L. C., C. F. Schmidt, and E. J. G. Peterman. “Kinesin studied with single-pair Forster resonance energy transfer.” In Biophysical Journal, 84:441A-442A. BIOPHYSICAL SOCIETY, 2003.Link to Item
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Mameren, J. van, F. Gittes, and C. F. Schmidt. “Flexural rigidity of microtubules and F-actin studied with optical tweezers.” In Biophysical Journal, 84:149A-149A. BIOPHYSICAL SOCIETY, 2003.Link to Item
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Addas, K. M., J. X. Tang, A. J. Levine, and C. F. Schmidt. “Extracting local and bulk viscoelasticity of entangled FD virus solutions by two-bead microrheology.” In Biophysical Journal, 82:497A-498A. BIOPHYSICAL SOCIETY, 2002.Link to Item
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Peterman, E. J. G., R. R. Agayan, F. Gittes, R. Kopelman, and C. F. Schmidt. “Resonance effects in optical trapping.” In Biophysical Journal, 82:496A-496A. BIOPHYSICAL SOCIETY, 2002.Link to Item
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Agayan, R. R., C. F. Schmidt, F. Gittes, and R. Kopelman. “Laser tweezing near resonance absorption.” In Proceedings of Spie the International Society for Optical Engineering, 4431:341–51, 2001. https://doi.org/10.1117/12.447444.Full Text
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Peterman, E. J. G., F. Gittes, W. Moehler, and C. F. Schmidt. “Optical tweezer experiments: Temperature effects and back focal plane interferometry.” In Biophysical Journal, 80:73A-73A. BIOPHYSICAL SOCIETY, 2001.Link to Item
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Schmidt, C. F., J. Von Mameren, J. Von Zon, W. Mohler, and F. Gittes. “Non-linear compliance of bead-to-filament attachment in three-bead motility assays.” In Biophysical Journal, 80:579A-579A. BIOPHYSICAL SOCIETY, 2001.Link to Item
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Stewart, R. J., M. D. Decastro, R. M. Fondecave, and C. F. Schmidt. “Single molecule motility assays with the kinesin-related ncd motor: Working strokes and kinetic parameters.” In Biophysical Journal, 80:512A-512A. BIOPHYSICAL SOCIETY, 2001.Link to Item
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deCastro, M. J., R. M. Fondecave, L. A. Clarke, C. F. Schmidt, and R. J. Stewart. “Working strokes generated by single molecules of the kinesin-related NCD motor.” In Biophysical Journal, 78:278A-278A. BIOPHYSICAL SOCIETY, 2000.Link to Item
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Clarke, L. A., R. M. Fondecave, M. J. deCastro, R. J. Stewart, and C. F. Schmidt. “Three-bead assay for kinesin motors.” In Biophysical Journal, 76:A43–A43. BIOPHYSICAL SOCIETY, 1999.Link to Item
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Moehler, W., F. Gittes, and C. F. Schmidt. “Fluctuations and force-displacement characteristics of beads bound to single actin filaments.” In Biophysical Journal, 76:A39–A39. BIOPHYSICAL SOCIETY, 1999.Link to Item
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Allersma, M. W., F. Gittes, M. J. deCastro, R. J. Stewart, and C. F. Schmidt. “High resolution two-dimensional detection of ncd motility with optical tweezers.” In Materials Research Society Symposium Proceedings, 489:85–90, 1998.
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Gittes, F., B. Schnurr, C. F. Schmidt, P. D. Olmsted, and F. C. Mackintosh. “Model for dynamic shear modulus of semiflexible polymer solutions.” In Materials Research Society Symposium Proceedings, 489:49–54, 1998.
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Mackintosh, F. C., F. Gittes, B. Schnurr, P. D. Olmsted, and C. F. Schmidt. “Viscoelasticity and its microscopic characterization in semiflexible biopolymer solutions.” In Materials Research Society Symposium Proceedings, 489:39–48, 1998.
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Schmidt, C. F., F. Gittes, M. W. Allersma, W. Mohler, and B. Schnurr. “Microscopic dynamics of proteins probed with optical tweezers.” In Abstracts of Papers of the American Chemical Society, 216:U681–U681. AMER CHEMICAL SOC, 1998.Link to Item
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Allersma, M. W., M. J. deCastro, R. Fondecave, R. J. Stewart, and C. F. Schmidt. “Evidence for non-processive ncd motility in vitro.” In Biophysical Journal, 74:A50–A50. BIOPHYSICAL SOCIETY, 1998.Link to Item
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Gittes, F., B. Schnurr, W. Moehler, P. D. Olmsted, J. V. Shah, M. Osterfield, P. A. Janmey, F. C. MacKintosh, and C. F. Schmidt. “Microscopic viscoelasticity in actin networks: A model system for semiflexible polymers.” In Biophysical Journal, 74:A361–A361. BIOPHYSICAL SOCIETY, 1998.Link to Item
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Gittes, F., and C. F. Schmidt. “Back-focal-plane detection of force and motion in optical traps.” In Biophysical Journal, 74:A183–A183. BIOPHYSICAL SOCIETY, 1998.Link to Item
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Lewis, M. K., P. Wolanin, C. F. Schmidt, V. A. Barnett, A. Gafni, and D. G. Steel. “Protein structural changes studied by near-field spectroscopy.” In Biophysical Journal, 74:A179–A179. BIOPHYSICAL SOCIETY, 1998.Link to Item
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Schnurr, B., F. Gittes, P. D. Olmsted, F. C. MacKintosh, and C. F. Schmidt. “Microrheology in actin gels: Experiment and theory.” In Biophysical Journal, 72:TU285–TU285. CELL PRESS, 1997.Link to Item
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Schnurr, B., F. Gittes, P. D. Olmsted, C. F. Schmidt, and F. C. Mackintosh. “Local viscoelasticity of biopolymer solutions.” In Materials Research Society Symposium Proceedings, 463:15–20, 1997.
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Allersma, M. W., D. R. Stom, and C. F. Schmidt. “Bending elasticity of individual cytoskeletal polymers measured by applying calibrated forces with optical tweezers.” In Biophysical Journal, 70:TU405–TU405. CELL PRESS, 1996.Link to Item
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Fritz, M., M. Radmacher, M. W. Allersma, J. P. Cleveland, R. J. Stewart, P. K. Hansma, and C. F. Schmidt. “Imaging microtubules in buffer solution using tapping mode atomic force microscopy.” In Proceedings of Spie the International Society for Optical Engineering, 2384:150–57, 1995.
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Radmacher, M., M. Fritz, M. W. Allersma, C. F. Schmidt, and P. K. Hansma. “Imaging adhesion forces on proteins with the atomic force microscope.” In Proceedings of Spie the International Society for Optical Engineering, 2384:136–43, 1995.
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SVOBODA, K., C. F. SCHMIDT, B. J. SCHNAPP, and S. M. BLOCK. “DIRECT OBSERVATION OF KINESIN STEPS.” In Biophysical Journal, 66:A353–A353. BIOPHYSICAL SOCIETY, 1994.Link to Item
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SVOBODA, K., C. F. SCHMIDT, D. BRANTON, and S. M. BLOCK. “ELASTIC PROPERTIES OF EXTRACTED RED-BLOOD-CELL MEMBRANE SKELETONS.” In Faseb Journal, 6:A523–A523. FEDERATION AMER SOC EXP BIOL, 1992.Link to Item
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