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Instability of myelin tubes under dehydration: deswelling of layered cylindrical structures.

Publication ,  Journal Article
Chen, CM; Schmidt, CF; Olmsted, PD; MacKintosh, FC
Published in: Physical review. E, Statistical, nonlinear, and soft matter physics
November 2001

We report experimental observations of an undulational instability of myelin figures. Motivated by this, we examine theoretically the deformation and possible instability of concentric, cylindrical, multilamellar membrane structures. Under conditions of osmotic stress (swelling or dehydration), we find a stable, deformed state in which the layer deformation is given by deltaR infinity r(square root[B(A)/(hB)]), where B(A) is the area compression modulus, B is the interlayer compression modulus, and h is the repeat distance of layers. Also, above a finite threshold of dehydration (or osmotic stress), we find that the system becomes unstable to undulations, first with a characteristic wavelength of order square root[xi(d)0], where xi is the standard smectic penetration depth and d0 is the thickness of dehydrated region.

Duke Scholars

Published In

Physical review. E, Statistical, nonlinear, and soft matter physics

DOI

EISSN

1550-2376

ISSN

1539-3755

Publication Date

November 2001

Volume

64

Issue

5 Pt 1

Start / End Page

050903

Related Subject Headings

  • Water
  • Osmotic Pressure
  • Myelin Sheath
  • Microscopy, Interference
  • Membrane Lipids
  • Macromolecular Substances
  • In Vitro Techniques
  • Fluids & Plasmas
  • Drug Stability
  • Biophysics
 

Citation

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Chen, C. M., Schmidt, C. F., Olmsted, P. D., & MacKintosh, F. C. (2001). Instability of myelin tubes under dehydration: deswelling of layered cylindrical structures. Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics, 64(5 Pt 1), 050903. https://doi.org/10.1103/physreve.64.050903
Chen, C. M., C. F. Schmidt, P. D. Olmsted, and F. C. MacKintosh. “Instability of myelin tubes under dehydration: deswelling of layered cylindrical structures.Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics 64, no. 5 Pt 1 (November 2001): 050903. https://doi.org/10.1103/physreve.64.050903.
Chen CM, Schmidt CF, Olmsted PD, MacKintosh FC. Instability of myelin tubes under dehydration: deswelling of layered cylindrical structures. Physical review E, Statistical, nonlinear, and soft matter physics. 2001 Nov;64(5 Pt 1):050903.
Chen, C. M., et al. “Instability of myelin tubes under dehydration: deswelling of layered cylindrical structures.Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics, vol. 64, no. 5 Pt 1, Nov. 2001, p. 050903. Epmc, doi:10.1103/physreve.64.050903.
Chen CM, Schmidt CF, Olmsted PD, MacKintosh FC. Instability of myelin tubes under dehydration: deswelling of layered cylindrical structures. Physical review E, Statistical, nonlinear, and soft matter physics. 2001 Nov;64(5 Pt 1):050903.

Published In

Physical review. E, Statistical, nonlinear, and soft matter physics

DOI

EISSN

1550-2376

ISSN

1539-3755

Publication Date

November 2001

Volume

64

Issue

5 Pt 1

Start / End Page

050903

Related Subject Headings

  • Water
  • Osmotic Pressure
  • Myelin Sheath
  • Microscopy, Interference
  • Membrane Lipids
  • Macromolecular Substances
  • In Vitro Techniques
  • Fluids & Plasmas
  • Drug Stability
  • Biophysics