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The East Asian Paradox: An Updated Position Statement on the Challenges to the Current Antithrombotic Strategy in Patients with Cardiovascular Disease.

Publication ,  Journal Article
Kim, HK; Tantry, US; Smith, SC; Jeong, MH; Park, S-J; Kim, MH; Lim, D-S; Shin, E-S; Park, D-W; Huo, Y; Chen, S-L; Bo, Z; Goto, S; Kimura, T ...
Published in: Thromb Haemost
April 2021

East Asian patients have reduced anti-ischemic benefits and increased bleeding risk during antithrombotic therapies compared with Caucasian patients. As potent P2Y12 receptor inhibitors (e.g., ticagrelor and prasugrel) and direct oral anticoagulants are commonly used in current daily practice, the unique risk-benefit trade-off in East Asians has been a topic of emerging interest. In this article, we propose updated evidence and future directions of antithrombotic treatment in East Asian patients.

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Published In

Thromb Haemost

DOI

EISSN

2567-689X

Publication Date

April 2021

Volume

121

Issue

4

Start / End Page

422 / 432

Location

Germany

Related Subject Headings

  • Treatment Outcome
  • Risk Factors
  • Risk Assessment
  • Platelet Aggregation Inhibitors
  • Humans
  • Hemorrhage
  • Fibrinolytic Agents
  • Cardiovascular System & Hematology
  • Cardiovascular Diseases
  • Asian People
 

Citation

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Kim, H. K., Tantry, U. S., Smith, S. C., Jeong, M. H., Park, S.-J., Kim, M. H., … Jeong, Y.-H. (2021). The East Asian Paradox: An Updated Position Statement on the Challenges to the Current Antithrombotic Strategy in Patients with Cardiovascular Disease. Thromb Haemost, 121(4), 422–432. https://doi.org/10.1055/s-0040-1718729
Kim, Hyun Kuk, Udaya S. Tantry, Sidney C. Smith, Myung Ho Jeong, Seung-Jung Park, Moo Hyun Kim, Do-Sun Lim, et al. “The East Asian Paradox: An Updated Position Statement on the Challenges to the Current Antithrombotic Strategy in Patients with Cardiovascular Disease.Thromb Haemost 121, no. 4 (April 2021): 422–32. https://doi.org/10.1055/s-0040-1718729.
Kim HK, Tantry US, Smith SC, Jeong MH, Park S-J, Kim MH, et al. The East Asian Paradox: An Updated Position Statement on the Challenges to the Current Antithrombotic Strategy in Patients with Cardiovascular Disease. Thromb Haemost. 2021 Apr;121(4):422–32.
Kim, Hyun Kuk, et al. “The East Asian Paradox: An Updated Position Statement on the Challenges to the Current Antithrombotic Strategy in Patients with Cardiovascular Disease.Thromb Haemost, vol. 121, no. 4, Apr. 2021, pp. 422–32. Pubmed, doi:10.1055/s-0040-1718729.
Kim HK, Tantry US, Smith SC, Jeong MH, Park S-J, Kim MH, Lim D-S, Shin E-S, Park D-W, Huo Y, Chen S-L, Bo Z, Goto S, Kimura T, Yasuda S, Chen W-J, Chan M, Aradi D, Geisler T, Gorog DA, Sibbing D, Lip GYH, Angiolillo DJ, Gurbel PA, Jeong Y-H. The East Asian Paradox: An Updated Position Statement on the Challenges to the Current Antithrombotic Strategy in Patients with Cardiovascular Disease. Thromb Haemost. 2021 Apr;121(4):422–432.
Journal cover image

Published In

Thromb Haemost

DOI

EISSN

2567-689X

Publication Date

April 2021

Volume

121

Issue

4

Start / End Page

422 / 432

Location

Germany

Related Subject Headings

  • Treatment Outcome
  • Risk Factors
  • Risk Assessment
  • Platelet Aggregation Inhibitors
  • Humans
  • Hemorrhage
  • Fibrinolytic Agents
  • Cardiovascular System & Hematology
  • Cardiovascular Diseases
  • Asian People