Paul Alfred Gurbel | Scholars@Duke

Paul Alfred Gurbel
Adjunct Professor in the Department of Medicine

Current Appointments & Affiliations

Adjunct Professor in the Department of Medicine, Medicine, Clinical Pharmacology, Medicine 2013

Contact Information

Background
Education, Training, & Certifications
- M.D., University of Maryland, Baltimore 1983
Duke Appointment History
- Associate, Medicine, Clinical Science Departments 1988 - 1989
Publications & Artistic Works
Selected Publications
- Books
  - Waksman, R., P. A. Gurbel, and M. A. Gaglia. Antiplatelet Therapy in Cardiovascular Disease, 2014. https://doi.org/10.1002/9781118493984.
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- Academic Articles
  - Kim, Hyun Kuk, Udaya S. Tantry, Sidney C. Smith, Myung Ho Jeong, Seung-Jung Park, Moo Hyun Kim, Do-Sun Lim, et al. “The East Asian Paradox: An Updated Position Statement on the Challenges to the Current Antithrombotic Strategy in Patients with Cardiovascular Disease.” Thromb Haemost 121, no. 4 (April 2021): 422–32. https://doi.org/10.1055/s-0040-1718729.
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  - Navarese, Eliano P., Lara Frediani, David E. Kandzari, Gianluca Caiazzo, Angela Marella Cenname, Bernardo Cortese, Tommaso Piva, et al. “Efficacy and safety of intracoronary epinephrine versus conventional treatments alone in STEMI patients with refractory coronary no-reflow during primary PCI: The RESTORE observational study.” Catheter Cardiovasc Interv 97, no. 4 (March 2021): 602–11. https://doi.org/10.1002/ccd.29113.
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  - Gurbel, Paul A., Kevin P. Bliden, and Udaya S. Tantry. “Defining platelet response to acetylsalicylic acid: the relation between inhibition of serum thromboxane B₂ and agonist-induced platelet aggregation.” Journal of Thrombosis and Thrombolysis 51, no. 2 (February 2021): 260–64. https://doi.org/10.1007/s11239-020-02334-x.
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  - Jeong, Young-Hoon, Bliden Kevin, Jong-Hwa Ahn, Rahul Chaudhary, Min Gyu Kang, Hyun Woong Park, Jin-Sin Koh, Yongwhi Park, Udaya S. Tantry, and Paul A. Gurbel. “Viscoelastic properties of clot formation and their clinical impact in East Asian versus Caucasian patients with stable coronary artery disease: a COMPARE-RACE analysis.” J Thromb Thrombolysis 51, no. 2 (February 2021): 454–65. https://doi.org/10.1007/s11239-020-02240-2.
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  - Kim, H. K., U. S. Tantry, H. W. Park, E. S. Shin, T. Geisler, D. A. Gorog, P. A. Gurbel, and Y. H. Jeong. “Ethnic difference of thrombogenicity in patients with cardiovascular disease: A pandora box to explain prognostic differences.” Korean Circulation Journal 51, no. 3 (February 1, 2021): 202–21. https://doi.org/10.4070/KCJ.2020.0537.
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  - Gurbel, Paul A., Kevin Bliden, Scott D. Barnett, Casey Witt, Heng Zou, and Udaya Tantry. “An Ex Vivo Study to Evaluate the Effect of Tegaserod on Platelet Activation and Aggregation.” J Cardiovasc Pharmacol Ther 26, no. 1 (January 2021): 40–50. https://doi.org/10.1177/1074248420942004.
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  - Chaudhary, Rahul, Kevin P. Bliden, Rolf P. Kreutz, Young-Hoon Jeong, Udaya S. Tantry, Jerrold H. Levy, and Paul A. Gurbel. “Race-Related disparities in COVID-19 thrombotic outcomes: Beyond social and economic explanations.” Eclinicalmedicine 29 (December 2020): 100647. https://doi.org/10.1016/j.eclinm.2020.100647.
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  - Kuliopulos, Athan, Paul A. Gurbel, Jeffrey J. Rade, Carey D. Kimmelstiel, Susan E. Turner, Kevin P. Bliden, Elizabeth K. Fletcher, Daniel H. Cox, Lidija Covic, and Lidija TRIP-PCI Investigators. “PAR1 (Protease-Activated Receptor 1) Pepducin Therapy Targeting Myocardial Necrosis in Coronary Artery Disease and Acute Coronary Syndrome Patients Undergoing Cardiac Catheterization: A Randomized, Placebo-Controlled, Phase 2 Study.” Arterioscler Thromb Vasc Biol 40, no. 12 (December 2020): 2990–3003. https://doi.org/10.1161/ATVBAHA.120.315168.
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  - Liu, Tiancheng, Jessica Hsiung, Su Zhao, Jessica Kost, Deepika Sreedhar, Carl V. Hanson, Kjerstie Olson, et al. “Quantification of antibody avidities and accurate detection of SARS-CoV-2 antibodies in serum and saliva on plasmonic substrates.” Nat Biomed Eng 4, no. 12 (December 2020): 1188–96. https://doi.org/10.1038/s41551-020-00642-4.
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  - Mahla, Elisabeth, Udaya S. Tantry, Michael Schoerghuber, and Paul A. Gurbel. “Platelet Function Testing in Patients on Antiplatelet Therapy before Cardiac Surgery.” Anesthesiology 133, no. 6 (December 1, 2020): 1263–76. https://doi.org/10.1097/ALN.0000000000003541.
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  - Bae, Jae Seok, Jong-Hwa Ahn, Jeong Yoon Jang, Sang Young Cho, Min Gyu Kang, Kye-Hwan Kim, Hyun Woong Park, et al. “The Impact of platelet-fibrin clot strength on occurrence and clinical outcomes of peripheral artery disease in patients with significant coronary artery disease.” J Thromb Thrombolysis 50, no. 4 (November 2020): 969–81. https://doi.org/10.1007/s11239-020-02103-w.
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  - Salsoso, Rocío, Talia F. Dalcoquio, Remo H. M. Furtado, André Franci, Carlos J. D. G. Barbosa, Paulo R. R. Genestreti, Celia M. C. Strunz, et al. “Relation of High Lipoprotein (a) Concentrations to Platelet Reactivity in Individuals with and Without Coronary Artery Disease.” Adv Ther 37, no. 11 (November 2020): 4568–84. https://doi.org/10.1007/s12325-020-01483-y.
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  - Verma, Shefali Setia, Thomas O. Bergmeijer, Li Gong, Jean-Luc Reny, Joshua P. Lewis, Braxton D. Mitchell, Dimitrios Alexopoulos, et al. “Genomewide Association Study of Platelet Reactivity and Cardiovascular Response in Patients Treated With Clopidogrel: A Study by the International Clopidogrel Pharmacogenomics Consortium.” Clin Pharmacol Ther 108, no. 5 (November 2020): 1067–77. https://doi.org/10.1002/cpt.1911.
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  - Rout, Amit, Sahib Singh, Sauradeep Sarkar, Immad Munawar, Aakash Garg, Christopher R. D’Adamo, Udaya S. Tantry, Ashwin Dharmadhikari, and Paul A. Gurbel. “Meta-Analysis of the Usefulness of Therapeutic Hypothermia After Cardiac Arrest.” Am J Cardiol 133 (October 15, 2020): 48–53. https://doi.org/10.1016/j.amjcard.2020.07.038.
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  - Dias, Joao D., Carlos G. Lopez-Espina, Kevin Bliden, Paul Gurbel, Jan Hartmann, and Hardean E. Achneck. “TEG®6s system measures the contributions of both platelet count and platelet function to clot formation at the site-of-care.” Platelets 31, no. 7 (October 2, 2020): 932–38. https://doi.org/10.1080/09537104.2019.1704713.
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  - Baber, Usman, George Dangas, Dominick Joseph Angiolillo, David Joel Cohen, Samin Kumar Sharma, Johny Nicolas, Carlo Briguori, et al. “Ticagrelor alone vs. ticagrelor plus aspirin following percutaneous coronary intervention in patients with non-ST-segment elevation acute coronary syndromes: TWILIGHT-ACS.” Eur Heart J 41, no. 37 (October 1, 2020): 3533–45. https://doi.org/10.1093/eurheartj/ehaa670.
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  - Rout, Amit, Udaya S. Tantry, Marko Novakovic, Ajaypaul Sukhi, and Paul A. Gurbel. “Targeted pharmacotherapy for ischemia reperfusion injury in acute myocardial infarction.” Expert Opin Pharmacother 21, no. 15 (October 2020): 1851–65. https://doi.org/10.1080/14656566.2020.1787987.
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  - Sherwood, Matthew, Kevin P. Bliden, Leonard Ilkhanoff, Ganesh Venkataraman, Adam Strickberger, Sharam Yazdani, Robert McSwain, et al. “Detailed thrombogenicity phenotyping and 1 year outcomes in patients undergoing WATCHMAN implantation: (TARGET-WATCHMAN) a case-control study.” J Thromb Thrombolysis 50, no. 3 (October 2020): 484–98. https://doi.org/10.1007/s11239-020-02205-5.
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  - Gurbel, Paul A., Kevin P. Bliden, Rahul Chaudhary, and Udaya S. Tantry. “First In-Human Experience With Inhaled Acetylsalicylic Acid for Immediate Platelet Inhibition: Comparison With Chewed and Swallowed Acetylsalicylic Acid.” Circulation 142, no. 13 (September 29, 2020): 1305–7. https://doi.org/10.1161/CIRCULATIONAHA.120.047477.
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  - Storey, Robert F., Paul A. Gurbel, Jurrien Ten Berg, Corine Bernaud, George D. Dangas, Jean-Marie Frenoux, Diana A. Gorog, et al. “Pharmacodynamics, pharmacokinetics, and safety of single-dose subcutaneous administration of selatogrel, a novel P2Y12 receptor antagonist, in patients with chronic coronary syndromes.” Eur Heart J 41, no. 33 (September 1, 2020): 3132–40. https://doi.org/10.1093/eurheartj/ehz807.
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  - Tantry, Udaya S., Kevin P. Bliden, Rahul Chaudhary, Marko Novakovic, Amit Rout, and Paul A. Gurbel. “Vorapaxar in the treatment of cardiovascular diseases.” Future Cardiol 16, no. 5 (September 2020): 373–84. https://doi.org/10.2217/fca-2019-0090.
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  - Gurbel, Paul A., Kevin P. Bliden, and Karsten Schrör. “Can an Old Ally Defeat a New Enemy?” Circulation 142, no. 4 (July 28, 2020): 315–17. https://doi.org/10.1161/CIRCULATIONAHA.120.047830.
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  - Navarese, Eliano P., Safi U. Khan, Michalina Kołodziejczak, Jacek Kubica, Sergio Buccheri, Christopher P. Cannon, Paul A. Gurbel, et al. “Comparative Efficacy and Safety of Oral P2Y12 Inhibitors in Acute Coronary Syndrome: Network Meta-Analysis of 52 816 Patients From 12 Randomized Trials.” Circulation 142, no. 2 (July 14, 2020): 150–60. https://doi.org/10.1161/CIRCULATIONAHA.120.046786.
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  - Gurbel, P. A., A. Rout, and U. S. Tantry. “Pharmacogenetic considerations in antiplatelet therapy.” Expert Review of Precision Medicine and Drug Development 5, no. 4 (July 3, 2020): 235–38. https://doi.org/10.1080/23808993.2020.1768844.
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  - Kim, H. K., U. S. Tantry, P. A. Gurbel, and Y. H. Jeong. “Another unmet need against residual risk of atherosclerotic cardiovascular disease: Can "thrombin pathway" be a new target for therapy?” Korean Circulation Journal 50 (July 1, 2020). https://doi.org/10.4070/KCJ.2020.0287.
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  - Lewis, Joshua P., Joshua D. Backman, Jean-Luc Reny, Thomas O. Bergmeijer, Braxton D. Mitchell, Marylyn D. Ritchie, Jean-Pierre Déry, et al. “Pharmacogenomic polygenic response score predicts ischaemic events and cardiovascular mortality in clopidogrel-treated patients.” Eur Heart J Cardiovasc Pharmacother 6, no. 4 (July 1, 2020): 203–10. https://doi.org/10.1093/ehjcvp/pvz045.
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  - Garg, Aakash, Amit Rout, Abhishek Sharma, Davit Sargsyan, Traymon Beavers, Udaya Tantry, Paul Gurbel, Sunil V. Rao, John B. Kostis, and Marc Cohen. “Safety and efficacy of antiplatelet regimens after percutaneous coronary intervention using drug eluting stents: A network meta-analysis of randomized controlled trials.” Prog Cardiovasc Dis 63, no. 3 (May 2020): 243–48. https://doi.org/10.1016/j.pcad.2020.03.018.
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  - Becker, Kristian C., Lydia Coulter Kwee, Megan L. Neely, Elizabeth Grass, Joseph A. Jakubowski, Keith A. A. Fox, Harvey D. White, et al. “Circulating MicroRNA Profiling in Non-ST Elevated Coronary Artery Syndrome Highlights Genomic Associations with Serial Platelet Reactivity Measurements.” Sci Rep 10, no. 1 (April 10, 2020): 6169. https://doi.org/10.1038/s41598-020-63263-6.
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  - Jeong, Young-Hoon, Yong-Lee Kim, Udaya Tantry, and Paul A. Gurbel. “Antithrombotic treatment strategies after PCI.” Lancet 395, no. 10227 (March 14, 2020): 866–67. https://doi.org/10.1016/S0140-6736(20)30030-1.
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  - Chaudhary, Rahul, Tushar Sharma, Jalaj Garg, Ajaypaul Sukhi, Kevin Bliden, Udaya Tantry, Mohit Turagam, Dhanunjaya Lakkireddy, and Paul Gurbel. “Direct oral anticoagulants: a review on the current role and scope of reversal agents.” J Thromb Thrombolysis 49, no. 2 (February 2020): 271–86. https://doi.org/10.1007/s11239-019-01954-2.
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  - Bliden, Kevin, Rahul Chaudhary, Athan Kuliopulos, Henry Tran, Hamid Taheri, Behnam Tehrani, Arnold Rosenblatt, Eliano Navarese, Udaya S. Tantry, and Paul A. Gurbel. “Effects of vorapaxar on clot characteristics, coagulation, inflammation, and platelet and endothelial function in patients treated with mono- and dual-antiplatelet therapy.” J Thromb Haemost 18, no. 1 (January 2020): 23–35. https://doi.org/10.1111/jth.14616.
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  - Kubica, Jacek, Piotr Adamski, Piotr Niezgoda, Dimitrios Alexopoulos, Jolita Badarienė, Andrzej Budaj, Katarzyna Buszko, et al. “Prolonged antithrombotic therapy in patients after acute coronary syndrome: A critical appraisal of current European Society of Cardiology guidelines.” Cardiol J 27, no. 6 (2020): 661–76. https://doi.org/10.5603/CJ.a2020.0132.
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  - Navarese, Eliano P., Rita L. Musci, Lara Frediani, Paul A. Gurbel, and Jacek Kubica. “Ion channel inhibition against COVID-19: A novel target for clinical investigation.” Cardiol J 27, no. 4 (2020): 421–24. https://doi.org/10.5603/CJ.a2020.0090.
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  - Rout, Amit, Ajaypaul Sukhi, Rahul Chaudhary, Kevin P. Bliden, Udaya S. Tantry, and Paul A. Gurbel. “Investigational drugs in phase II clinical trials for acute coronary syndromes.” Expert Opin Investig Drugs 29, no. 1 (January 2020): 33–47. https://doi.org/10.1080/13543784.2020.1708324.
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  - Mehran, Roxana, Usman Baber, Samin K. Sharma, David J. Cohen, Dominick J. Angiolillo, Carlo Briguori, Jin Y. Cha, et al. “Ticagrelor with or without Aspirin in High-Risk Patients after PCI.” N Engl J Med 381, no. 21 (November 21, 2019): 2032–42. https://doi.org/10.1056/NEJMoa1908419.
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  - Ramotowski, Bogumił, Paul A. Gurbel, Udaya Tantry, and Andrzej Budaj. “Smoking and cardiovascular diseases: paradox greater than expected?” Pol Arch Intern Med 129, no. 10 (October 30, 2019): 700–706. https://doi.org/10.20452/pamw.14931.
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  - Chaudhary, Rahul, Ajaypaul Sukhi, Rohit Chaudhary, Manila Jindal, Ankit Vyas, Amit Rout, Kevin Bliden, Udaya Tantry, and Paul Gurbel. “Gender differences in thrombogenicity among patients with angina and non-obstructive coronary artery disease.” J Thromb Thrombolysis 48, no. 3 (October 2019): 373–81. https://doi.org/10.1007/s11239-019-01901-1.
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  - Tantry, Udaya S., and Paul A. Gurbel. “Secondary prevention of ischaemic stroke: more evidence to block two pathways affecting platelet activation.” Eur Heart J Qual Care Clin Outcomes 5, no. 4 (October 1, 2019): 275–78. https://doi.org/10.1093/ehjqcco/qcz041.
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  - Tantry, Udaya S., Rahul Chaudhary, and Paul A. Gurbel. “In search for an optimal antithrombotic regimen in patients with atrial fibrillation undergoing stenting.” Kardiol Pol 77, no. 9 (September 23, 2019): 817–19. https://doi.org/10.33963/KP.14983.
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  - Gurbel, Paul A., Eliano P. Navarese, and Udaya S. Tantry. “The optimal antithrombotic regimen to prevent post-CABG adverse events: an ongoing controversy.” Eur Heart J 40, no. 29 (August 1, 2019): 2441–43. https://doi.org/10.1093/eurheartj/ehz263.
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  - Gurbel, Paul A., Keith A. A. Fox, Udaya S. Tantry, Hugo Ten Cate, and Jeffrey I. Weitz. “Combination Antiplatelet and Oral Anticoagulant Therapy in Patients With Coronary and Peripheral Artery Disease.” Circulation 139, no. 18 (April 30, 2019): 2170–85. https://doi.org/10.1161/CIRCULATIONAHA.118.033580.
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  - Huo, Y., Y. H. Jeong, Y. Gong, D. Wang, B. He, J. Chen, G. Fu, et al. “2018 update of expert consensus statement on antiplatelet therapy in East Asian patients with ACS or undergoing PCI.” Science Bulletin 64, no. 3 (February 15, 2019): 166–79. https://doi.org/10.1016/j.scib.2018.12.020.
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  - Bliden, Kevin P., Gabe Raviv, Udaya S. Tantry, Rahul Chaudhary, John W. Cochran, Eliano P. Navarese, Tricia Brannan, Ankit Vyas, and Paul A. Gurbel. “"Blueprinting" thrombogenicity and antithrombotic drug response at the bedside in patients presenting emergently with symptoms of acute stroke.” J Thromb Thrombolysis 47, no. 2 (February 2019): 192–99. https://doi.org/10.1007/s11239-019-01813-0.
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  - Koh, Jin-Sin, Yongwhi Park, Jong-Hwa Ahn, Min Gyu Kang, Kye-Hwan Kim, Jae Seok Bae, Hyun Woong Park, et al. “Influence of Amlodipine on Haemostatic Measurements during Clopidogrel Treatment in Patients with Coronary Artery Disease.” Thrombosis and Haemostasis 119, no. 2 (February 2019): 264–73. https://doi.org/10.1055/s-0038-1676795.
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  - Åstrand, Magnus, Carl Amilon, Daniel Röshammar, Anders Himmelmann, Dominick J. Angiolillo, Robert F. Storey, Paul A. Gurbel, Marc P. Bonaca, and Bengt Hamrén. “Pharmacokinetic-pharmacodynamic modelling of platelet response to ticagrelor in stable coronary artery disease and prior myocardial infarction patients.” Br J Clin Pharmacol 85, no. 2 (February 2019): 413–21. https://doi.org/10.1111/bcp.13812.
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  - Dracoulakis, Marianna Deway Andrade, Paul Gurbel, Marco Cattaneo, Herlon Saraiva Martins, José Carlos Nicolau, and Roberto Kalil Filho. “High Residual Platelet Reactivity during Aspirin Therapy in Patients with Non-St Segment Elevation Acute Coronary Syndrome: Comparison Between Initial and Late Phases.” Arq Bras Cardiol 113, no. 3 (2019): 357–63. https://doi.org/10.5935/abc.20190146.
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  - Gurbel, Paul, Udaya Tantry, and Steven Weisman. “A narrative review of the cardiovascular risks associated with concomitant aspirin and NSAID use.” J Thromb Thrombolysis 47, no. 1 (January 2019): 16–30. https://doi.org/10.1007/s11239-018-1764-5.
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  - Jeong, Y. H., U. S. Tantry, and P. A. Gurbel. “Temporal variability of platelet reactivity phenotype: Another barrier to personalized antiplatelet strategy guided by platelet function testing.” Korean Circulation Journal 49, no. 11 (January 1, 2019): 1062–65. https://doi.org/10.4070/kcj.2019.0260.
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  - Mahla, Elisabeth, Udaya S. Tantry, Florian Prüller, and Paul A. Gurbel. “Is There a Role for Preoperative Platelet Function Testing in Patients Undergoing Cardiac Surgery During Antiplatelet Therapy?” Circulation 138, no. 19 (November 6, 2018): 2145–59. https://doi.org/10.1161/CIRCULATIONAHA.118.035160.
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  - Tantry, U. S., E. P. Navarese, K. P. Bliden, and P. A. Gurbel. “The potential of genotype-guided antiplatelet therapy: promises and challenges.” Expert Review of Precision Medicine and Drug Development 3, no. 6 (November 2, 2018): 371–77. https://doi.org/10.1080/23808993.2018.1552517.
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  - Gurbel, Paul A., Palak Shah, Shashank Desai, and Udaya S. Tantry. “Antithrombotic Strategies and Device Thrombosis.” Cardiol Clin 36, no. 4 (November 2018): 541–50. https://doi.org/10.1016/j.ccl.2018.06.008.
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  - Hinohara, Tomoya T., Matthew T. Roe, Harvey D. White, Keith A. A. Fox, Deepak L. Bhatt, Christian Hamm, Paul A. Gurbel, et al. “Outcomes of Patients Receiving Downstream Revascularization After Initial Medical Management for Non-ST-Segment Elevation Acute Coronary Syndromes (From the TRILOGY ACS Trial).” Am J Cardiol 122, no. 8 (October 15, 2018): 1322–29. https://doi.org/10.1016/j.amjcard.2018.06.052.
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  - Navarese, Eliano P., Bernhard Wernly, Michael Lichtenauer, Aniela M. Petrescu, Michalina Kołodziejczak, Alexander Lauten, Lara Frediani, et al. “Dual vs single antiplatelet therapy in patients with lower extremity peripheral artery disease - A meta-analysis.” Int J Cardiol 269 (October 15, 2018): 292–97. https://doi.org/10.1016/j.ijcard.2018.07.009.
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  - Brener, Sorin J., Ajay J. Kirtane, Michael J. Rinaldi, Thomas D. Stuckey, Bernhard Witzenbichler, Giora Weisz, Franz-Josef Neumann, et al. “Prediction of Ischemic and Bleeding Events Using the Dual Antiplatelet Therapy Score in an Unrestricted Percutaneous Coronary Intervention Population.” Circ Cardiovasc Interv 11, no. 10 (October 2018): e006853. https://doi.org/10.1161/CIRCINTERVENTIONS.118.006853.
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  - Tantry, Udaya, Rahul Chaudhary, Jacek Kubica, Kevin Bliden, and Paul A. Gurbel. “Cangrelor for the treatment of patients with Arterial Thrombosis.” Expert Opin Pharmacother 19, no. 12 (August 2018): 1389–98. https://doi.org/10.1080/14656566.2018.1506767.
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  - Giustino, Gennaro, Björn Redfors, Ajay J. Kirtane, Roxana Mehran, George D. Dangas, Bernhard Witzenbichler, Franz-Josef Neumann, et al. “Platelet Reactivity and Risk of Ischemic Stroke After Coronary Drug-Eluting Stent Implantation: From the ADAPT-DES Study.” Jacc Cardiovasc Interv 11, no. 13 (July 9, 2018): 1277–86. https://doi.org/10.1016/j.jcin.2018.01.263.
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  - Venkataraman, Ganesh, Kevin P. Bliden, Udaya S. Tantry, and Paul A. Gurbel. “Thromboembolism after WATCHMANTM in a clopidogrel non-responder: A case for concern?” Catheter Cardiovasc Interv 92, no. 1 (July 2018): 200–202. https://doi.org/10.1002/ccd.27402.
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  - Navarese, Eliano P., Michalina Kołodziejczak, Aniela Petrescu, Bernhard Wernly, Michael Lichtenauer, Alexander Lauten, Antonino Buffon, et al. “Role of proprotein convertase subtilisin/kexin type 9 inhibitors in patients with coronary artery disease undergoing percutaneous coronary intervention.” Expert Rev Cardiovasc Ther 16, no. 6 (June 2018): 419–29. https://doi.org/10.1080/14779072.2018.1474099.
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  - Rana, Rajashree, Tianfang Huang, Georgios Koukos, Elizabeth K. Fletcher, Susan E. Turner, Andrew Shearer, Paul A. Gurbel, et al. “Noncanonical Matrix Metalloprotease 1-Protease-Activated Receptor 1 Signaling Drives Progression of Atherosclerosis.” Arterioscler Thromb Vasc Biol 38, no. 6 (June 2018): 1368–80. https://doi.org/10.1161/ATVBAHA.118.310967.
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  - Gurbel, Paul A., Udaya S. Tantry, Denise D’Andrea, Thomas Chung, John H. Alexander, Kevin P. Bliden, Samuel D. Wright, and Pierluigi Tricoci. “Evaluation of potential antiplatelet effects of CSL112 (Apolipoprotein A-I [Human]) in patients with atherosclerosis: results from a phase 2a study.” J Thromb Thrombolysis 45, no. 4 (May 2018): 469–76. https://doi.org/10.1007/s11239-018-1644-z.
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  - Tantry, Udaya S., Eliano P. Navarese, Aung Myat, Rahul Chaudhary, and Paul A. Gurbel. “Combination oral antithrombotic therapy for the treatment of myocardial infarction: recent developments.” Expert Opin Pharmacother 19, no. 7 (May 2018): 653–65. https://doi.org/10.1080/14656566.2018.1457649.
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  - Navarese, Eliano P., Jennifer G. Robinson, Mariusz Kowalewski, Michalina Kolodziejczak, Felicita Andreotti, Kevin Bliden, Udaya Tantry, Jacek Kubica, Paolo Raggi, and Paul A. Gurbel. “Association Between Baseline LDL-C Level and Total and Cardiovascular Mortality After LDL-C Lowering: A Systematic Review and Meta-analysis.” Jama 319, no. 15 (April 17, 2018): 1566–79. https://doi.org/10.1001/jama.2018.2525.
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  - Bergmeijer, Thomas O., Jean-Luc Reny, Ruth E. Pakyz, Li Gong, Joshua P. Lewis, Eun-Young Kim, Daniel Aradi, et al. “Genome-wide and candidate gene approaches of clopidogrel efficacy using pharmacodynamic and clinical end points-Rationale and design of the International Clopidogrel Pharmacogenomics Consortium (ICPC).” Am Heart J 198 (April 2018): 152–59. https://doi.org/10.1016/j.ahj.2017.12.010.
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  - Bae, Jae S., Jong-Hwa Ahn, Udaya S. Tantry, Paul A. Gurbel, and Young-Hoon Jeong. “Should Antithrombotic Treatment Strategies in East Asians Differ from Caucasians?” Curr Vasc Pharmacol 16, no. 5 (2018): 459–76. https://doi.org/10.2174/1570161116666180117103238.
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  - Navarese, E. P., B. Wernly, M. Lichtenauer, M. Pepe, W. Wanha, G. Ferrante, L. Frediani, et al. “Prime time for the sweet spot in timing of coronary invasive approach in patients with non-ST elevation myocardial infarction.” Journal of Thoracic Disease 10, no. 1 (January 1, 2018): 17–20. https://doi.org/10.21037/jtd.2017.11.125.
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  - Tantry, Udaya S., Eliano P. Navarese, Aung Myat, and Paul A. Gurbel. “Selection of P2Y12 Inhibitor in Percutaneous Coronary Intervention and/or Acute Coronary Syndrome.” Prog Cardiovasc Dis 60, no. 4–5 (January 2018): 460–70. https://doi.org/10.1016/j.pcad.2018.01.003.
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  - Tantry, Udaya S., Eliano P. Navarese, Kevin P. Bliden, and Paul A. Gurbel. “Acetylsalicylic acid and clopidogrel hyporesponsiveness following acute coronary syndromes.” Kardiol Pol 76, no. 9 (2018): 1312–19. https://doi.org/10.5603/KP.a2018.0159.
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  - Chaudhary, Rahul, Denny Mathew, Kevin Bliden, Udaya S. Tantry, Tushar Sharma, Martin G. Gesheff, Christopher J. Franzese, Shachi Pandya, Peter P. Toth, and Paul A. Gurbel. “Low-density lipoprotein 4: a novel predictor of coronary artery disease severity.” Curr Med Res Opin 33, no. 11 (November 2017): 1979–84. https://doi.org/10.1080/03007995.2017.1365052.
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  - Shah, Palak, Udaya S. Tantry, Kevin P. Bliden, and Paul A. Gurbel. “Bleeding and thrombosis associated with ventricular assist device therapy.” J Heart Lung Transplant 36, no. 11 (November 2017): 1164–73. https://doi.org/10.1016/j.healun.2017.05.008.
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  - Winter, Max-Paul, Erik L. Grove, Raffaele De Caterina, Diana A. Gorog, Ingo Ahrens, Tobias Geisler, Paul A. Gurbel, Udaya Tantry, Eliano P. Navarese, and Jolanta M. Siller-Matula. “Advocating cardiovascular precision medicine with P2Y12 receptor inhibitors.” Eur Heart J Cardiovasc Pharmacother 3, no. 4 (October 1, 2017): 221–34. https://doi.org/10.1093/ehjcvp/pvw044.
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  - Gurbel, Paul A., Eliano P. Navarese, and Udaya S. Tantry. “Exploration of PCSK9 as a Cardiovascular Risk Factor: Is There a Link to the Platelet?” J Am Coll Cardiol 70, no. 12 (September 19, 2017): 1463–66. https://doi.org/10.1016/j.jacc.2017.07.779.
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  - Stuckey, Thomas D., Ajay J. Kirtane, Bruce R. Brodie, Bernhard Witzenbichler, Claire Litherland, Giora Weisz, Michael J. Rinaldi, et al. “Impact of Aspirin and Clopidogrel Hyporesponsiveness in Patients Treated With Drug-Eluting Stents: 2-Year Results of a Prospective, Multicenter Registry Study.” Jacc Cardiovasc Interv 10, no. 16 (August 28, 2017): 1607–17. https://doi.org/10.1016/j.jcin.2017.05.059.
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  - Tantry, Udaya S., Young-Hoon Jeong, and Paul A. Gurbel. “More Evidence for Non-P2Y12-Mediated Effects of Ticagrelor.” Jacc Cardiovasc Interv 10, no. 16 (August 28, 2017): 1659–61. https://doi.org/10.1016/j.jcin.2017.06.014.
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  - Chen, Gailing, Kevin P. Bliden, Rahul Chaudhary, Fang Liu, Himabindu Kaza, Eliano P. Navarese, Udaya S. Tantry, and Paul A. Gurbel. “Central aortic pulse pressure, thrombogenicity and cardiovascular risk.” J Thromb Thrombolysis 44, no. 2 (August 2017): 223–33. https://doi.org/10.1007/s11239-017-1524-y.
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  - Kolodziejczak, Michalina, Felicita Andreotti, Mariusz Kowalewski, Antonino Buffon, Marco Matteo Ciccone, Gianfranco Parati, Pietro Scicchitano, et al. “Implantable Cardioverter-Defibrillators for Primary Prevention in Patients With Ischemic or Nonischemic Cardiomyopathy: A Systematic Review and Meta-analysis.” Ann Intern Med 167, no. 2 (July 18, 2017): 103–11. https://doi.org/10.7326/M17-0120.
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  - Gurbel, Paul A., Christopher R. deFilippi, Kevin P. Bliden, and Udaya S. Tantry. “HIV infection, ACS, PCI and high platelet reactivity: ingredients for a perfect thrombotic storm.” Eur Heart J 38, no. 21 (June 1, 2017): 1687–89. https://doi.org/10.1093/eurheartj/ehw630.
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  - Park, Yongwhi, Udaya S. Tantry, Jin-Sin Koh, Jong-Hwa Ahn, Min Gyu Kang, Kye Hwan Kim, Jeong Yoon Jang, et al. “Novel role of platelet reactivity in adverse left ventricular remodelling after ST-segment elevation myocardial infarction: The REMODELING Trial.” Thromb Haemost 117, no. 5 (May 3, 2017): 911–22. https://doi.org/10.1160/TH16-10-0744.
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  - Bliden, Kevin P., Rahul Chaudhary, Nafees Mohammed, Adina A. Muresan, Carlos G. Lopez-Espina, Eli Cohen, Gabriel Raviv, et al. “Determination of non-Vitamin K oral anticoagulant (NOAC) effects using a new-generation thrombelastography TEG 6s system.” J Thromb Thrombolysis 43, no. 4 (May 2017): 437–45. https://doi.org/10.1007/s11239-017-1477-1.
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  - Secemsky, Eric A., Robert W. Yeh, Dean J. Kereiakes, Donald E. Cutlip, David J. Cohen, P Gabriel Steg, Christopher P. Cannon, et al. “Mortality Following Cardiovascular and Bleeding Events Occurring Beyond 1 Year After Coronary Stenting: A Secondary Analysis of the Dual Antiplatelet Therapy (DAPT) Study.” Jama Cardiol 2, no. 5 (May 1, 2017): 478–87. https://doi.org/10.1001/jamacardio.2017.0063.
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  - Patel, Manesh R., F Gerry R. Fowkes, and William R. Hiatt. “Ticagrelor versus Clopidogrel in Peripheral Artery Disease.” N Engl J Med 376, no. 15 (April 13, 2017): 1488–89. https://doi.org/10.1056/NEJMc1701197.
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  - Jakubowski, Joseph A., David Erlinge, Dimitrios Alexopoulos, David S. Small, Kenneth J. Winters, Paul A. Gurbel, and Dominick J. Angiolillo. “The Rationale for and Clinical Pharmacology of Prasugrel 5 mg.” Am J Cardiovasc Drugs 17, no. 2 (April 2017): 109–21. https://doi.org/10.1007/s40256-016-0202-3.
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  - Gurbel, Paul A., Matthew J. Price, Jeffrey R. Dahlen, and Udaya S. Tantry. “ANTARCTIC: platelet function testing to adjust therapy.” Lancet 389, no. 10075 (March 25, 2017): 1193. https://doi.org/10.1016/S0140-6736(17)30780-8.
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  - Koh, Jin-Sin, Yongwhi Park, Udaya S. Tantry, Jong-Hwa Ahn, Min Gyu Kang, Kyehwan Kim, Jeong Yoon Jang, et al. “Pharmacodynamic effects of a new fixed-dose clopidogrel-aspirin combination compared with separate administration of clopidogrel and aspirin in patients treated with coronary stents: The ACCEL-COMBO trial.” Platelets 28, no. 2 (March 2017): 187–93. https://doi.org/10.1080/09537104.2016.1206197.
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  - Tantry, Udaya S., and Paul A. Gurbel. “Rapid Desensitization of the Patients With Aspirin Hypersensitivity and Coronary Artery Disease.” Circ Cardiovasc Interv 10, no. 2 (February 2017). https://doi.org/10.1161/CIRCINTERVENTIONS.117.004881.
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  - Navarese, Eliano P., Paul A. Gurbel, Felicita Andreotti, Michalina Marta Kołodziejczak, Suetonia C. Palmer, Sofia Dias, Antonino Buffon, et al. “Prevention of contrast-induced acute kidney injury in patients undergoing cardiovascular procedures-a systematic review and network meta-analysis.” Plos One 12, no. 2 (2017): e0168726. https://doi.org/10.1371/journal.pone.0168726.
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  - Sharma, Tushar, Kevin Bliden, Rahul Chaudhary, Udaya Tantry, and Paul A. Gurbel. “Efficacy of aspirin (325 mg) + omeprazole (40 mg) in treating coronary artery disease.” Expert Opin Pharmacother 18, no. 1 (January 2017): 123–31. https://doi.org/10.1080/14656566.2016.1269747.
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  - Gurbel, Paul A., Kevin P. Bliden, Rahul Chaudhary, Jeff Patrick, Fang Liu, Gailing Chen, Christopher McLeod, and Udaya S. Tantry. “Antiplatelet Effect Durability of a Novel, 24-Hour, Extended-Release Prescription Formulation of Acetylsalicylic Acid in Patients With Type 2 Diabetes Mellitus.” Am J Cardiol 118, no. 12 (December 15, 2016): 1941–47. https://doi.org/10.1016/j.amjcard.2016.08.088.
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  - Kim, Ju H., Palak Shah, Udaya S. Tantry, and Paul A. Gurbel. “Coagulation Abnormalities in Heart Failure: Pathophysiology and Therapeutic Implications.” Curr Heart Fail Rep 13, no. 6 (December 2016): 319–28. https://doi.org/10.1007/s11897-016-0308-6.
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  - Myat, Aung, Udaya S. Tantry, Jacek Kubica, and Paul A. Gurbel. “Current controversies in the use of aspirin and ticagrelor for the treatment of thrombotic events.” Expert Rev Cardiovasc Ther 14, no. 12 (December 2016): 1361–70. https://doi.org/10.1080/14779072.2016.1247693.
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  - Gurbel, Paul A., Young-Hoon Jeong, and Udaya S. Tantry. “The Dogged Search for Cryptic Effects of Ticagrelor: Wishful Thinking or Real Benefits Beyond P2Y12 Inhibition?” Circulation 134, no. 22 (November 29, 2016): 1720–23. https://doi.org/10.1161/CIRCULATIONAHA.116.024710.
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  - Gurbel, Paul A., Kevin P. Bliden, Brian A. Baker, Jeffrey Dahlen, and Udaya S. Tantry. “Cigarette Smoking, Clopidogrel Responsiveness, and Hemoglobin Level.” Jacc Cardiovasc Interv 9, no. 22 (November 28, 2016): 2364. https://doi.org/10.1016/j.jcin.2016.09.026.
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  - Cornel, Jan H., E Magnus Ohman, Benjamin Neely, Joseph A. Jakubowski, Deepak L. Bhatt, Harvey D. White, Diego Ardissino, et al. “Relationship of Platelet Reactivity With Bleeding Outcomes During Long-Term Treatment With Dual Antiplatelet Therapy for Medically Managed Patients With Non-ST-Segment Elevation Acute Coronary Syndromes.” J Am Heart Assoc 5, no. 11 (November 4, 2016). https://doi.org/10.1161/JAHA.116.003977.
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  - Gurbel, Paul A., Kevin P. Bliden, Udaya S. Tantry, Amy L. Monroe, Adina A. Muresan, Norman E. Brunner, Carlos G. Lopez-Espina, et al. “First report of the point-of-care TEG: A technical validation study of the TEG-6S system.” Platelets 27, no. 7 (November 2016): 642–49. https://doi.org/10.3109/09537104.2016.1153617.
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  - Gurbel, Paul A., and Udaya S. Tantry. “Antiplatelet therapy: What have we learned from the ANTARCTIC trial?” Nat Rev Cardiol 13, no. 11 (November 2016): 639–40. https://doi.org/10.1038/nrcardio.2016.167.
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  - Chaudhary, Rahul, Katayoon Saadin, Kevin P. Bliden, William S. Harris, Bao Dinh, Tushar Sharma, Udaya S. Tantry, and Paul A. Gurbel. “Risk factors associated with plasma omega-3 fatty acid levels in patients with suspected coronary artery disease.” Prostaglandins Leukot Essent Fatty Acids 113 (October 2016): 40–45. https://doi.org/10.1016/j.plefa.2016.08.009.
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  - Bliden, Kevin P., Rahul Chaudhary, Luis R. Lopez, Rongras Damrongwatanasuk, Kirk Guyer, Martin G. Gesheff, Christopher J. Franzese, Himabindu Kaza, Udaya S. Tantry, and Paul A. Gurbel. “Oxidized Low-Density Lipoprotein-β2-Glycoprotein I Complex But Not Free Oxidized LDL Is Associated With the Presence and Severity of Coronary Artery Disease.” Am J Cardiol 118, no. 5 (September 1, 2016): 673–78. https://doi.org/10.1016/j.amjcard.2016.06.023.
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  - Chaudhary, Rahul, Kevin P. Bliden, Jalaj Garg, Nafees Mohammed, Udaya Tantry, Denny Mathew, Peter P. Toth, et al. “Statin therapy and inflammation in patients with diabetes treated with high dose aspirin.” J Diabetes Complications 30, no. 7 (September 2016): 1365–70. https://doi.org/10.1016/j.jdiacomp.2016.05.002.
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  - Kubica, Jacek, Aldona Kubica, Bernd Jilma, Piotr Adamski, Eva-Luise Hobl, Eliano Pio Navarese, Jolanta Maria Siller-Matula, et al. “Impact of morphine on antiplatelet effects of oral P2Y12 receptor inhibitors.” Int J Cardiol 215 (July 15, 2016): 201–8. https://doi.org/10.1016/j.ijcard.2016.04.077.
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  - Bliden, Kevin P., Udaya S. Tantry, Rahul Chaudhary, Seunghwan Byun, and Paul A. Gurbel. “Extended-release acetylsalicylic acid for secondary prevention of stroke and cardiovascular events.” Expert Rev Cardiovasc Ther 14, no. 7 (July 2016): 779–91. https://doi.org/10.1080/14779072.2016.1188005.
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  - Giustino, Gennaro, Ajay J. Kirtane, Usman Baber, Philippe Généreux, Bernhard Witzenbichler, Franz-Josef Neumann, Giora Weisz, et al. “Impact of Anemia on Platelet Reactivity and Ischemic and Bleeding Risk: From the Assessment of Dual Antiplatelet Therapy With Drug-Eluting Stents Study.” Am J Cardiol 117, no. 12 (June 15, 2016): 1877–83. https://doi.org/10.1016/j.amjcard.2016.03.034.
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  - Bedeir, Kareem, Kevin Bliden, Udaya Tantry, Paul A. Gurbel, and Elisabeth Mahla. “Timing of Coronary Bypass Surgery in Patients Receiving Clopidogrel: The Role of VerifyNow.” Can J Cardiol 32, no. 6 (June 2016): 724–25. https://doi.org/10.1016/j.cjca.2016.01.038.
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  - Gurbel, Paul A., and Udaya S. Tantry. “Antithrombotic therapy in medically managed patients with non-ST-segment elevation acute coronary syndromes.” Heart 102, no. 11 (June 1, 2016): 882–92. https://doi.org/10.1136/heartjnl-2014-306695.
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  - Navarese, Eliano P., Michalina Kolodziejczak, Dean J. Kereiakes, Udaya S. Tantry, Christopher O’Connor, and Paul A. Gurbel. “Proprotein Convertase Subtilisin/Kexin Type 9 Monoclonal Antibodies for Acute Coronary Syndrome: A Narrative Review.” Ann Intern Med 164, no. 9 (May 3, 2016): 600–607. https://doi.org/10.7326/M15-2994.
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  - Kwon, Tae Jung, Udaya S. Tantry, Yongwhi Park, Young-Min Choi, Jong-Hwa Ahn, Kye Hwan Kim, Jin-Sin Koh, et al. “Influence of platelet reactivity on BARC classification in East Asian patients undergoing percutaneous coronary intervention. Results of the ACCEL-BLEED study.” Thromb Haemost 115, no. 5 (May 2, 2016): 979–92. https://doi.org/10.1160/TH15-05-0366.
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  - Gurbel, Paul A., Young-Hoon Jeong, Eliano P. Navarese, and Udaya S. Tantry. “Platelet-Mediated Thrombosis: From Bench to Bedside.” Circ Res 118, no. 9 (April 29, 2016): 1380–91. https://doi.org/10.1161/CIRCRESAHA.115.307016.
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  - Gurbel, Paul A., and Udaya S. Tantry. “Deciding about prolonged ticagrelor therapy in coronary clot formers: an ongoing dilemma.” Eur Heart J 37, no. 14 (April 7, 2016): 1143–44. https://doi.org/10.1093/eurheartj/ehv573.
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  - Bliden, Kevin P., Udaya S. Tantry, Martin G. Gesheff, Christopher J. Franzese, Shachi Pandya, Peter P. Toth, Denny P. Mathew, Rahul Chaudhary, and Paul A. Gurbel. “Thrombin-Induced Platelet-Fibrin Clot Strength Identified by Thrombelastography: A Novel Prothrombotic Marker of Coronary Artery Stent Restenosis.” J Interv Cardiol 29, no. 2 (April 2016): 168–78. https://doi.org/10.1111/joic.12277.
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  - Chaudhary, Rahul, Kevin P. Bliden, Udaya S. Tantry, Nafees Mohammed, Denny Mathew, Martin G. Gesheff, Christopher J. Franzese, and Paul A. Gurbel. “Association of weight gain with coronary artery disease, inflammation and thrombogenicity.” J Thromb Thrombolysis 41, no. 3 (April 2016): 394–403. https://doi.org/10.1007/s11239-015-1327-y.
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  - Reny, Jean-Luc, Pierre Fontana, Willibald Hochholzer, Franz Josef Neumann, Jurriën Ten Berg, Paul W. Janssen, Tobias Geisler, et al. “Vascular risk levels affect the predictive value of platelet reactivity for the occurrence of MACE in patients on clopidogrel. Systematic review and meta-analysis of individual patient data.” Thromb Haemost 115, no. 4 (April 2016): 844–55. https://doi.org/10.1160/TH15-09-0742.
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  - Doll, Jacob A., Megan L. Neely, Matthew T. Roe, Paul W. Armstrong, Harvey D. White, Dorairaj Prabhakaran, Kenneth J. Winters, et al. “Impact of CYP2C19 Metabolizer Status on Patients With ACS Treated With Prasugrel Versus Clopidogrel.” J Am Coll Cardiol 67, no. 8 (March 1, 2016): 936–47. https://doi.org/10.1016/j.jacc.2015.12.036.
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  - King, K. R., L. P. Grazette, D. N. Paltoo, J. T. McDevitt, S. K. Sia, P. M. Barrett, F. S. Apple, et al. “Point-of-Care Technologies for Precision Cardiovascular Care and Clinical Research: National Heart, Lung, and Blood Institute Working Group.” Jacc: Basic to Translational Science 1, no. 1–2 (February 1, 2016): 73–86. https://doi.org/10.1016/j.jacbts.2016.01.008.
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  - Bliden, Kevin P., Jeff Patrick, Andrew T. Pennell, Udaya S. Tantry, and Paul A. Gurbel. “Drug delivery and therapeutic impact of extended-release acetylsalicylic acid.” Future Cardiol 12, no. 1 (January 2016): 45–58. https://doi.org/10.2217/fca.15.60.
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  - Gurbel, Paul A., Kevin P. Bliden, Susan E. Turner, Udaya S. Tantry, Martin G. Gesheff, Travis P. Barr, Lidija Covic, and Athan Kuliopulos. “Cell-Penetrating Pepducin Therapy Targeting PAR1 in Subjects With Coronary Artery Disease.” Arterioscler Thromb Vasc Biol 36, no. 1 (January 2016): 189–97. https://doi.org/10.1161/ATVBAHA.115.306777.
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  - Tantry, Udaya S., and Paul A. Gurbel. “A Bigger Look Into the "Therapeutic Window" of Platelet Reactivity to Adenosine Diphosphate.” Jacc Cardiovasc Interv 8, no. 15 (December 28, 2015): 1988–89. https://doi.org/10.1016/j.jcin.2015.10.008.
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  - Tantry, Udaya S., Fang Liu, Gailing Chen, and Paul A. Gurbel. “Vorapaxar in the secondary prevention of atherothrombosis.” Expert Rev Cardiovasc Ther 13, no. 12 (December 2015): 1293–1305. https://doi.org/10.1586/14779072.2015.1109447.
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  - Gurbel, Paul A., and Udaya S. Tantry. “Inhibited and Uninhibited Platelet Deposition Within a Thrombus: Does It Depend on the Antiplatelet Drug?” Arterioscler Thromb Vasc Biol 35, no. 10 (October 2015): 2081–82. https://doi.org/10.1161/ATVBAHA.115.306371.
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  - Jeong, Young-Hoon, Sidney C. Smith, and Paul A. Gurbel. “Long-Term Use of Ticagrelor in Patients with Prior Myocardial Infarction.” N Engl J Med 373, no. 13 (September 24, 2015): 1273–74. https://doi.org/10.1056/NEJMc1508692.
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  - Tricoci, Pierluigi, Denise M. D’Andrea, Paul A. Gurbel, Zhenling Yao, Marina Cuchel, Brion Winston, Robert Schott, et al. “Infusion of Reconstituted High-Density Lipoprotein, CSL112, in Patients With Atherosclerosis: Safety and Pharmacokinetic Results From a Phase 2a Randomized Clinical Trial.” J Am Heart Assoc 4, no. 8 (August 25, 2015): e002171. https://doi.org/10.1161/JAHA.115.002171.
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  - Kowalewski, Mariusz, Volker Schulze, Sergio Berti, Ron Waksman, Jacek Kubica, Michalina Kołodziejczak, Antonino Buffon, et al. “Complete revascularisation in ST-elevation myocardial infarction and multivessel disease: meta-analysis of randomised controlled trials.” Heart 101, no. 16 (August 2015): 1309–17. https://doi.org/10.1136/heartjnl-2014-307293.
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  - Aradi, Dániel, Ajay Kirtane, Laurent Bonello, Paul A. Gurbel, Udaya S. Tantry, Kurt Huber, Matthias K. Freynhofer, et al. “Bleeding and stent thrombosis on P2Y12-inhibitors: collaborative analysis on the role of platelet reactivity for risk stratification after percutaneous coronary intervention.” Eur Heart J 36, no. 27 (July 14, 2015): 1762–71. https://doi.org/10.1093/eurheartj/ehv104.
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  - Navarese, Eliano Pio, Michalina Kolodziejczak, Volker Schulze, Paul A. Gurbel, Udaya Tantry, Yingfeng Lin, Maximilian Brockmeyer, et al. “Effects of Proprotein Convertase Subtilisin/Kexin Type 9 Antibodies in Adults With Hypercholesterolemia: A Systematic Review and Meta-analysis.” Ann Intern Med 163, no. 1 (July 7, 2015): 40–51. https://doi.org/10.7326/M14-2957.
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  - Baber, Usman, Roxana Mehran, Ajay J. Kirtane, Paul A. Gurbel, Georgios Christodoulidis, Akiko Maehara, Bernhard Witzenbichler, et al. “Prevalence and impact of high platelet reactivity in chronic kidney disease: results from the Assessment of Dual Antiplatelet Therapy with Drug-Eluting Stents registry.” Circ Cardiovasc Interv 8, no. 6 (June 2015): e001683. https://doi.org/10.1161/CIRCINTERVENTIONS.115.001683.
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  - Liu, Fang, Udaya S. Tantry, and Paul A. Gurbel. “P2Y12 receptor inhibitors for secondary prevention of ischemic stroke.” Expert Opin Pharmacother 16, no. 8 (June 2015): 1149–65. https://doi.org/10.1517/14656566.2015.1035256.
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  - Mahla, Elisabeth, Udaya S. Tantry, and Paul A. Gurbel. “Platelet Function Testing Before CABG is Recommended in the Guidelines: But Do We Have Enough Evidence?” J Interv Cardiol 28, no. 3 (June 2015): 233–35. https://doi.org/10.1111/joic.12194.
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  - Rafeedheen, Rahil, Kevin P. Bliden, Fang Liu, Udaya S. Tantry, and Paul A. Gurbel. “Novel antiplatelet agents in cardiovascular medicine.” Curr Treat Options Cardiovasc Med 17, no. 6 (June 2015): 383. https://doi.org/10.1007/s11936-015-0383-0.
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  - Franzese, Christopher J., Kevin P. Bliden, Martin G. Gesheff, Shachi Pandya, Kirk E. Guyer, Anand Singla, Udaya S. Tantry, Peter P. Toth, and Paul A. Gurbel. “Relation of fish oil supplementation to markers of atherothrombotic risk in patients with cardiovascular disease not receiving lipid-lowering therapy.” Am J Cardiol 115, no. 9 (May 1, 2015): 1204–11. https://doi.org/10.1016/j.amjcard.2015.02.002.
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  - Gurbel, Paul A., Rolf P. Kreutz, Kevin P. Bliden, and Udaya S. Tantry. “Platelet activation and pneumonia: is soluble p-selectin the right marker?” J Am Coll Cardiol 65, no. 14 (April 14, 2015): 1492–93. https://doi.org/10.1016/j.jacc.2014.12.061.
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  - Jung, Jung Hwa, Udaya S. Tantry, Paul A. Gurbel, and Young-Hoon Jeong. “Current antiplatelet treatment strategy in patients with diabetes mellitus.” Diabetes Metab J 39, no. 2 (April 2015): 95–113. https://doi.org/10.4093/dmj.2015.39.2.95.
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  - Lhermusier, Thibault, Michael J. Lipinski, Udaya S. Tantry, Ricardo O. Escarcega, Nevin Baker, Kevin P. Bliden, Marco A. Magalhaes, et al. “Meta-analysis of direct and indirect comparison of ticagrelor and prasugrel effects on platelet reactivity.” Am J Cardiol 115, no. 6 (March 15, 2015): 716–23. https://doi.org/10.1016/j.amjcard.2014.12.029.
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  - Gurbel, Paul A., Athan Kuliopulos, and Udaya S. Tantry. “G-protein-coupled receptors signaling pathways in new antiplatelet drug development.” Arterioscler Thromb Vasc Biol 35, no. 3 (March 2015): 500–512. https://doi.org/10.1161/ATVBAHA.114.303412.
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  - Gurbel, Paul A., Eliano Pio Navarese, and Udaya S. Tantry. “What is the best anticoagulant therapy during primary percutaneous coronary intervention for acute myocardial infarction?” Pol Arch Med Wewn 125, no. 6 (2015): 461–70. https://doi.org/10.20452/pamw.2890.
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  - Gurbel, Paul A., Martin G. Gesheff, Christopher J. Franzese, Kevin P. Bliden, and Udaya S. Tantry. “Is light transmittance aggregometry still a useful tool to assess pharmacodynamic effects of antiplatelet therapy?” Platelets 26, no. 6 (2015): 608–9. https://doi.org/10.3109/09537104.2014.920497.
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  - Lee, Kyounghoon, Sang-Yong Yoo, Jon Suh, Keun Ho Park, Yongwhi Park, Udaya S. Tantry, Ki-Soo Park, et al. “Efficacy of cilostazol on inhibition of platelet aggregation, inflammation and myonecrosis in acute coronary syndrome patients undergoing percutaneous coronary intervention: The ACCEL-LOADING-ACS (ACCELerated Inhibition of Platelet Aggregation, Inflammation and Myonecrosis by Adjunctive Cilostazol Loading in Patients With Acute Coronary Syndrome) study.” Int J Cardiol 190 (2015): 370–75. https://doi.org/10.1016/j.ijcard.2015.04.180.
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  - Kahn, S. R., S. Shapiro, T. Ducruet, P. S. Wells, M. A. Rodger, M. J. Kovacs, D. Anderson, et al. “Graduated compression stockings to treat acute leg pain associated with proximal DVT. A randomised controlled trial.” Thromb Haemost 112, no. 6 (December 2014): 1137–41. https://doi.org/10.1160/TH14-05-0430.
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  - Park, Y., Y. -. H. Jeong, U. S. Tantry, J. H. Ahn, K. H. Kim, J. -. S. Koh, J. -. R. Park, et al. “Effect of adjunctive dipyridamole to DAPT on platelet function profiles in stented patients with high platelet reactivity. The result of the ACCEL-DIP Study.” Thromb Haemost 112, no. 6 (December 2014): 1198–1208. https://doi.org/10.1160/TH14-01-0040.
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  - Tantry, Udaya S., Martin Gesheff, Fang Liu, Kevin P. Bliden, and Paul A. Gurbel. “Resistance to antiplatelet drugs: what progress has been made?” Expert Opin Pharmacother 15, no. 17 (December 2014): 2553–64. https://doi.org/10.1517/14656566.2014.968126.
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  - Lev, Eli I., Kevin P. Bliden, Young-Hoon Jeong, Shachi Pandya, Kelly Kang, Christopher Franzese, Udaya S. Tantry, and Paul A. Gurbel. “Influence of race and sex on thrombogenicity in a large cohort of coronary artery disease patients.” J Am Heart Assoc 3, no. 5 (October 20, 2014): e001167. https://doi.org/10.1161/JAHA.114.001167.
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  - Alexopoulos, Dimitrios, Ioanna Xanthopoulou, Robert F. Storey, Kevin P. Bliden, Udaya S. Tantry, Dominick J. Angiolillo, and Paul A. Gurbel. “Platelet reactivity during ticagrelor maintenance therapy: a patient-level data meta-analysis.” Am Heart J 168, no. 4 (October 2014): 530–36. https://doi.org/10.1016/j.ahj.2014.06.026.
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  - Gurbel, P. A., T. O. Bergmeijer, U. S. Tantry, J. M. ten Berg, D. J. Angiolillo, S. James, T. L. Lindahl, et al. “The effect of CYP2C19 gene polymorphisms on the pharmacokinetics and pharmacodynamics of prasugrel 5-mg, prasugrel 10-mg and clopidogrel 75-mg in patients with coronary artery disease.” Thromb Haemost 112, no. 3 (September 2, 2014): 589–97. https://doi.org/10.1160/TH13-10-0891.
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  - Gesheff, Martin G., Christopher J. Franzese, Kevin P. Bliden, Chase J. Contino, Rahil Rafeedheen, Udaya S. Tantry, and Paul A. Gurbel. “Review of pharmacokinetic and pharmacodynamic modeling and safety of proton pump inhibitors and aspirin.” Expert Rev Clin Pharmacol 7, no. 5 (September 2014): 645–53. https://doi.org/10.1586/17512433.2014.945428.
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  - Bliden, K. P., A. Singla, M. G. Gesheff, P. P. Toth, A. Tabrizchi, G. Ens, K. Guyer, et al. “Statin therapy and thromboxane generation in patients with coronary artery disease treated with high-dose aspirin.” Thromb Haemost 112, no. 2 (August 2014): 323–31. https://doi.org/10.1160/TH14-01-0094.
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  - Gurbel, Paul A., Brian A. Baker, William L. Bailey, Kevin P. Bliden, and Udaya S. Tantry. “Unravelling the smokers' paradox: cigarette smoking, high-risk coronary artery disease and enhanced clinical efficacy of oral P2Y₁₂ inhibitors.” Thromb Haemost 111, no. 6 (June 2014): 1187–90. https://doi.org/10.1160/TH13-08-0642.
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  - Gurbel, Paul A., Rahil Rafeedheen, and Udaya S. Tantry. “Update: Acute coronary syndromes (V). Personalized antiplatelet therapy.” Rev Esp Cardiol (Engl Ed) 67, no. 6 (June 2014): 480–87. https://doi.org/10.1016/j.rec.2014.01.012.
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  - Koh, Jin-Sin, In-Sook Kim, Udaya S. Tantry, Seong-Eun Yoon, Yongwhi Park, Sang Yeong Cho, Eun-Ju Lee, et al. “Pharmacodynamic efficacy and safety of adjunctive cilostazol loading to clopidogrel and aspirin loading: the results of the ACCEL-LOADING (Accelerated Platelet Inhibition by Cilostazol Loading) study.” Int J Cardiol 174, no. 1 (June 1, 2014): 129–32. https://doi.org/10.1016/j.ijcard.2014.03.081.
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  - Erlinge, David, Stefan James, Suman Duvvuru, Joseph A. Jakubowski, Henrik Wagner, Christoph Varenhorst, Udaya S. Tantry, et al. “Clopidogrel metaboliser status based on point-of-care CYP2C19 genetic testing in patients with coronary artery disease.” Thromb Haemost 111, no. 5 (May 5, 2014): 943–50. https://doi.org/10.1160/TH13-09-0767.
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  - Kubica, Jacek, Marek Kozinski, Eliano Pio Navarese, Udaya Tantry, Aldona Kubica, Jolanta Maria Siller-Matula, Young-Hoon Jeong, Tomasz Fabiszak, Anna Andruszkiewicz, and Paul Alfred Gurbel. “Cangrelor: an emerging therapeutic option for patients with coronary artery disease.” Curr Med Res Opin 30, no. 5 (May 2014): 813–28. https://doi.org/10.1185/03007995.2014.880050.
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  - Angiolillo, Dominick J., Nicholas Curzen, Paul Gurbel, Paul Vaitkus, Fred Lipkin, Wei Li, Joseph A. Jakubowski, Marjorie Zettler, Mark B. Effron, and Dietmar Trenk. “Pharmacodynamic evaluation of switching from ticagrelor to prasugrel in patients with stable coronary artery disease: Results of the SWAP-2 Study (Switching Anti Platelet-2).” J Am Coll Cardiol 63, no. 15 (April 22, 2014): 1500–1509. https://doi.org/10.1016/j.jacc.2013.11.032.
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  - Gurbel, Paul A., Elisabeth Mahla, and Udaya S. Tantry. “The enigmatic search for optimal DAPT duration.” Eur Heart J 35, no. 15 (April 2014): 951–54. https://doi.org/10.1093/eurheartj/eht487.
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  - Gurbel, Paul A., Kevin P. Bliden, and Udaya S. Tantry. “Letter by Grbel et al regarding article, "administration of a loading dose has no additive effect on platelet aggregation during the switch from ongoing clopidogrel treatment to ticagrelor in patients with acute coronary syndrome".” Circ Cardiovasc Interv 7, no. 2 (April 2014): 273. https://doi.org/10.1161/CIRCINTERVENTIONS.114.001323.
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  - Jeong, Young-Hoon, Kevin P. Bliden, Alan R. Shuldiner, Udaya S. Tantry, and Paul A. Gurbel. “Thrombin-induced platelet-fibrin clot strength: relation to high on-clopidogrel platelet reactivity, genotype, and post-percutaneous coronary intervention outcomes.” Thromb Haemost 111, no. 4 (April 1, 2014): 713–24. https://doi.org/10.1160/TH13-08-0643.
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  - Gouya, Ghazaleh, Jasmin Arrich, Michael Wolzt, Kurt Huber, Freek W. A. Verheugt, Paul A. Gurbel, Agnes Pirker-Kees, and Jolanta M. Siller-Matula. “Antiplatelet treatment for prevention of cerebrovascular events in patients with vascular diseases: a systematic review and meta-analysis.” Stroke 45, no. 2 (February 2014): 492–503. https://doi.org/10.1161/STROKEAHA.113.002590.
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  - Gurbel, Paul A., and Udaya S. Tantry. “Antiplatelet and anticoagulant agents in heart failure: current status and future perspectives.” Jacc Heart Fail 2, no. 1 (February 2014): 1–14. https://doi.org/10.1016/j.jchf.2013.07.007.
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  - Ahn, J. H., U. S. Tantry, K. H. Kim, P. Gurbel, and Y. H. Jeong. “PRASFIT-ACS: Important evidence against a “one-guideline-fits-all-races” approach to antiplatelet therapy.” Circulation Journal 78, no. 10 (January 1, 2014): 2563. https://doi.org/10.1253/circj.CJ-14-0663.
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  - Gurbel, P. A., R. Rafeedheen, and U. S. Tantry. “Personalized antiplatelet therapy.” Revista Espanola De Cardiologia 67, no. 6 (January 1, 2014): 480–87. https://doi.org/10.1016/j.recesp.2014.01.013.
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  - Park, Yongwhi, Jin Mu Jung, Udaya S. Tantry, Kyehwan Kim, Jin Sin Koh, Jeong Rang Park, Seok-Jae Hwang, et al. “Pharmacodynamic effects of cilostazol versus clopidogrel in stented patients under proton pump inhibitor co-administration: the ACCEL-PARAZOL study.” J Atheroscler Thromb 21, no. 11 (2014): 1121–39. https://doi.org/10.5551/jat.24109.
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  - Tantry, Udaya S., Young-Hoon Jeong, and Paul A. Gurbel. “The clopidogrel-statin interaction.” Circ J 78, no. 3 (2014): 592–94. https://doi.org/10.1253/circj.cj-14-0068.
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  - Tantry, Udaya S., Laurent Bonello, Daniel Aradi, Matthew J. Price, Young-Hoon Jeong, Dominick J. Angiolillo, Gregg W. Stone, et al. “Consensus and update on the definition of on-treatment platelet reactivity to adenosine diphosphate associated with ischemia and bleeding.” J Am Coll Cardiol 62, no. 24 (December 17, 2013): 2261–73. https://doi.org/10.1016/j.jacc.2013.07.101.
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  - Kalra, Kiran, Christopher J. Franzese, Martin G. Gesheff, Eli I. Lev, Shachi Pandya, Kevin P. Bliden, Udaya S. Tantry, and Paul A. Gurbel. “Pharmacology of antiplatelet agents.” Curr Atheroscler Rep 15, no. 12 (December 2013): 371. https://doi.org/10.1007/s11883-013-0371-3.
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  - Bliden, Kevin P., Michael Brener, Martin G. Gesheff, Christopher J. Franzese, Ali Tabrizchi, Udaya Tantry, and Paul A. Gurbel. “PA tablets: investigational compounds combining aspirin and omeprazole for cardioprotection.” Future Cardiol 9, no. 6 (November 2013): 785–97. https://doi.org/10.2217/fca.13.67.
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  - Tantry, Udaya S., Elisabeth Mahla, Martin G. Gesheff, and Paul A. Gurbel. “Importance of measurement of platelet reactivity to ADP in patients with coronary artery disease: an historical account.” Expert Rev Cardiovasc Ther 11, no. 11 (November 2013): 1547–56. https://doi.org/10.1586/14779072.2013.839382.
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  - Gurbel, P. A., and U. S. Tantry. “The role of platelet function testing in risk stratification and clinical decision-making.” Interventional Cardiology Clinics 2, no. 4 (October 1, 2013): 607–14. https://doi.org/10.1016/j.iccl.2013.05.009.
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  - Jeong, Young-Hoon, Udaya S. Tantry, Ji Hyun Min, Yongwhi Park, Eliano Pio Navarese, Jin-Sin Koh, Jeong Rang Park, et al. “Influence of platelet reactivity and inflammation on peri-procedural myonecrosis in East Asian patients undergoing elective percutaneous coronary intervention.” Int J Cardiol 168, no. 1 (September 20, 2013): 427–35. https://doi.org/10.1016/j.ijcard.2012.09.132.
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  - Doraiswamy, Vijay A., Marvin J. Slepian, Martin G. Gesheff, Udaya S. Tantry, and Paul A. Gurbel. “Potential role of oral anticoagulants in the treatment of patients with coronary artery disease: focus on dabigatran.” Expert Rev Cardiovasc Ther 11, no. 9 (September 2013): 1259–67. https://doi.org/10.1586/14779072.2013.827469.
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  - Curzen, Nicholas, Paul A. Gurbel, Aung Myat, Deepak L. Bhatt, and Simon R. Redwood. “What is the optimum adjunctive reperfusion strategy for primary percutaneous coronary intervention?” Lancet 382, no. 9892 (August 17, 2013): 633–43. https://doi.org/10.1016/S0140-6736(13)61453-1.
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  - Stone, Gregg W., Bernhard Witzenbichler, Giora Weisz, Michael J. Rinaldi, Franz-Josef Neumann, D Christopher Metzger, Timothy D. Henry, et al. “Platelet reactivity and clinical outcomes after coronary artery implantation of drug-eluting stents (ADAPT-DES): a prospective multicentre registry study.” Lancet 382, no. 9892 (August 17, 2013): 614–23. https://doi.org/10.1016/S0140-6736(13)61170-8.
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  - Erlinge, David, Paul A. Gurbel, Stefan James, Tomas L. Lindahl, Peter Svensson, Jurrien M. Ten Berg, David P. Foley, et al. “Prasugrel 5 mg in the very elderly attenuates platelet inhibition but maintains noninferiority to prasugrel 10 mg in nonelderly patients: the GENERATIONS trial, a pharmacodynamic and pharmacokinetic study in stable coronary artery disease patients.” J Am Coll Cardiol 62, no. 7 (August 13, 2013): 577–83. https://doi.org/10.1016/j.jacc.2013.05.023.
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  - Gurbel, Paul A., Kevin P. Bliden, Douglas K. Logan, Dean J. Kereiakes, Kenneth C. Lasseter, Alex White, Dominick J. Angiolillo, et al. “The influence of smoking status on the pharmacokinetics and pharmacodynamics of clopidogrel and prasugrel: the PARADOX study.” J Am Coll Cardiol 62, no. 6 (August 6, 2013): 505–12. https://doi.org/10.1016/j.jacc.2013.03.037.
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  - Myat, Aung, Yousif Ahmad, Shouvik Haldar, Udaya S. Tantry, Simon R. Redwood, Paul A. Gurbel, and Gregory Yh Lip. “Is bleeding a necessary evil? The inherent risk of antithrombotic pharmacotherapy used for stroke prevention in atrial fibrillation.” Expert Rev Cardiovasc Ther 11, no. 8 (August 2013): 1029–49. https://doi.org/10.1586/14779072.2013.815423.
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  - Obonska, Karolina, Eliano Pio Navarese, Alexandra Lansky, Giuseppe Tarantini, Roberta Rossini, Marek Kozinski, Giuseppe Musumeci, et al. “Low-dose of oral factor Xa inhibitors in patients with a recent acute coronary syndrome: a systematic review and meta-analysis of randomized trials.” Atherosclerosis 229, no. 2 (August 2013): 482–88. https://doi.org/10.1016/j.atherosclerosis.2013.04.022.
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  - Tantry, Udaya S., and Paul A. Gurbel. “The next 10 years in personalized medicine in cardiology.” Expert Rev Cardiovasc Ther 11, no. 8 (August 2013): 933–35. https://doi.org/10.1586/14779072.2013.814823.
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  - Gurbel, Paul A., and Udaya S. Tantry. “P2Y12 Receptor Blockade and Myocardial Perfusion.” Jacc Cardiovasc Interv 6, no. 7 (July 2013): 684–86. https://doi.org/10.1016/j.jcin.2013.04.006.
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  - Kim, In-Suk, Young-Hoon Jeong, Udaya S. Tantry, Yongwhi Park, Dong-Hyun Lee, Kevin P. Bliden, Jin-Sin Koh, et al. “Relation between the vasodilator-stimulated phosphoprotein phosphorylation assay and light transmittance aggregometry in East Asian patients after high-dose clopidogrel loading.” Am Heart J 166, no. 1 (July 2013): 95–103. https://doi.org/10.1016/j.ahj.2013.03.030.
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  - Jeong, Y. -. H., K. A. Abadilla, U. S. Tantry, Y. Park, J. -. S. Koh, C. H. Kwak, J. -. Y. Hwang, and P. A. Gurbel. “Influence of CYP2C19*2 and *3 loss-of-function alleles on the pharmacodynamic effects of standard- and high-dose clopidogrel in East Asians undergoing percutaneous coronary intervention: the results of the ACCEL-DOUBLE-2N3 study.” J Thromb Haemost 11, no. 6 (June 2013): 1194–97. https://doi.org/10.1111/jth.12200.
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  - Gurbel, Paul A., and Udaya S. Tantry. “Triple antithrombotic therapy with prasugrel in the stented patient: concern for more bleeding.” J Am Coll Cardiol 61, no. 20 (May 21, 2013): 2067–69. https://doi.org/10.1016/j.jacc.2013.02.032.
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  - Bliden, Kevin P., Brian A. Baker, Thomas D. Nolin, Young-Hoon Jeong, William L. Bailey, Udaya S. Tantry, and Paul A. Gurbel. “Thienopyridine efficacy and cigarette smoking status.” Am Heart J 165, no. 5 (May 2013): 693–703. https://doi.org/10.1016/j.ahj.2012.12.024.
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  - Dahlen, J. R., M. J. Price, H. Parise, and P. A. Gurbel. “Evaluating the clinical usefulness of platelet function testing: considerations for the proper application and interpretation of performance measures.” Thromb Haemost 109, no. 5 (May 2013): 808–16. https://doi.org/10.1160/TH12-08-0608.
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  - Swiger, Kristopher J., Omair Yousuf, Kevin P. Bliden, Udaya S. Tantry, and Paul A. Gurbel. “Cigarette smoking and clopidogrel interaction.” Curr Cardiol Rep 15, no. 5 (May 2013): 361. https://doi.org/10.1007/s11886-013-0361-7.
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  - Lewis, Joshua P., Kathleen Ryan, Jeffrey R. O’Connell, Richard B. Horenstein, Coleen M. Damcott, Quince Gibson, Toni I. Pollin, et al. “Genetic variation in PEAR1 is associated with platelet aggregation and cardiovascular outcomes.” Circ Cardiovasc Genet 6, no. 2 (April 2013): 184–92. https://doi.org/10.1161/CIRCGENETICS.111.964627.
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  - Navarese, Eliano Pio, David Austin, Paul A. Gurbel, Felicita Andreotti, Udaya Tantry, Stefan James, Antonino Buffon, et al. “Drug-coated balloons in treatment of in-stent restenosis: a meta-analysis of randomised controlled trials.” Clin Res Cardiol 102, no. 4 (April 2013): 279–87. https://doi.org/10.1007/s00392-012-0532-3.
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  - Tantry, Udaya S., Young-Hoon Jeong, Eliano P. Navarese, Jacek Kubica, and Paul A. Gurbel. “Influence of genetic polymorphisms on platelet function, response to antiplatelet drugs and clinical outcomes in patients with coronary artery disease.” Expert Rev Cardiovasc Ther 11, no. 4 (April 2013): 447–62. https://doi.org/10.1586/erc.13.20.
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  - Navarese, Eliano P., Paul A. Gurbel, Felicita Andreotti, Udaya Tantry, Young-Hoon Jeong, Marek Kozinski, Thomas Engstrøm, et al. “Optimal timing of coronary invasive strategy in non-ST-segment elevation acute coronary syndromes: a systematic review and meta-analysis.” Ann Intern Med 158, no. 4 (February 19, 2013): 261–70. https://doi.org/10.7326/0003-4819-158-4-201302190-00006.
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  - Gurbel, Paul A., Kevin P. Bliden, John G. Fort, Young-Hoon Jeong, Alan Shuldiner, Sumbul Chai, Tania Gesheff, et al. “Spaced administration of PA32540 and clopidogrel results in greater platelet inhibition than synchronous administration of enteric-coated aspirin and enteric-coated omeprazole and clopidogrel.” Am Heart J 165, no. 2 (February 2013): 176–82. https://doi.org/10.1016/j.ahj.2012.07.032.
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  - Saucedo, Jorge F., Dominick J. Angiolillo, Roger DeRaad, Andrew L. Frelinger, Paul A. Gurbel, Timothy M. Costigan, Joseph A. Jakubowski, et al. “Decrease in high on-treatment platelet reactivity (HPR) prevalence on switching from clopidogrel to prasugrel: insights from the switching anti-platelet (SWAP) study.” Thromb Haemost 109, no. 2 (February 2013): 347–55. https://doi.org/10.1160/TH12-06-0378.
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  - Grześk, Grzegorz, Marek Kozinski, Udaya S. Tantry, Michal Wicinski, Tomasz Fabiszak, Eliano P. Navarese, Elzbieta Grzesk, Young-Hoon Jeong, Paul A. Gurbel, and Jacek Kubica. “High-dose, but not low-dose, aspirin impairs anticontractile effect of ticagrelor following ADP stimulation in rat tail artery smooth muscle cells.” Biomed Res Int 2013 (2013): 928271. https://doi.org/10.1155/2013/928271.
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  - Jeong, Young-Hoon, Kevin P. Bliden, Mark J. Antonino, Udaya S. Tantry, and Paul A. Gurbel. “Usefulness of thrombelastography platelet mapping assay to measure the antiplatelet effect of P2Y(12) receptor inhibitors and high on-treatment platelet reactivity.” Platelets 24, no. 2 (2013): 166–69. https://doi.org/10.3109/09537104.2012.675108.
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  - Lewis, Joshua P., Richard B. Horenstein, Kathleen Ryan, Jeffrey R. O’Connell, Quince Gibson, Braxton D. Mitchell, Keith Tanner, et al. “The functional G143E variant of carboxylesterase 1 is associated with increased clopidogrel active metabolite levels and greater clopidogrel response.” Pharmacogenet Genomics 23, no. 1 (January 2013): 1–8. https://doi.org/10.1097/FPC.0b013e32835aa8a2.
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  - Singla, Anand, Kevin P. Bliden, Young-Hoon Jeong, Katrina Abadilla, Mark J. Antonino, William C. Muse, Denny P. Mathew, Oscar Bailon, Udaya S. Tantry, and Paul A. Gurbel. “Platelet reactivity and thrombogenicity in postmenopausal women.” Menopause 20, no. 1 (January 2013): 57–63. https://doi.org/10.1097/gme.0b013e31825ebafd.
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  - Tantry, Udaya S., and Paul A. Gurbel. “Antiplatelet drug resistance and variability in response: the role of antiplatelet therapy monitoring.” Curr Pharm Des 19, no. 21 (2013): 3795–3815. https://doi.org/10.2174/1381612811319210006.
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  - Gurbel, P. A., D. Erlinge, E. M. Ohman, B. Neely, M. Neely, S. G. Goodman, K. Huber, et al. “Platelet Function During Extended Prasugrel and Clopidogrel Therapy for Patients With ACS Treated Without Revascularization: The TRILOGY ACS Platelet Function Substudy.” Jama, November 4, 2012, 1–10. https://doi.org/10.1001/jama.2012.17312.
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  - Jeong, Young-Hoon, Udaya S. Tantry, Yongwhi Park, Tae Jung Kwon, Jeong Rang Park, Seok-Jae Hwang, Kevin P. Bliden, et al. “Pharmacodynamic effect of cilostazol plus standard clopidogrel versus double-dose clopidogrel in patients with type 2 diabetes undergoing percutaneous coronary intervention.” Diabetes Care 35, no. 11 (November 2012): 2194–97. https://doi.org/10.2337/dc11-2351.
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  - Roe, Matthew T., Paul W. Armstrong, Keith A. A. Fox, Harvey D. White, Dorairaj Prabhakaran, Shaun G. Goodman, Jan H. Cornel, et al. “Prasugrel versus clopidogrel for acute coronary syndromes without revascularization.” N Engl J Med 367, no. 14 (October 4, 2012): 1297–1309. https://doi.org/10.1056/NEJMoa1205512.
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  - Gurbel, P. A., T. D. Nolin, and U. S. Tantry. “Influence of smoking on treatment with clopidogrel - In reply.” Jama Journal of the American Medical Association 308, no. 13 (October 3, 2012): 1323–24. https://doi.org/10.1001/2012.jama.11193.
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  - Navarese, Eliano Pio, Paul Gurbel, Udaya Tantry, Karolina Obonska, Adam Sukiennik, and Jacek Kubica. “Caution in interpreting the findings from small observational studies.” Int J Cardiol 160, no. 1 (September 20, 2012): 71. https://doi.org/10.1016/j.ijcard.2012.05.084.
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  - Park, Yongwhi, Young-Hoon Jeong, Udaya S. Tantry, Jong Hwa Ahn, Tae Jung Kwon, Jeong Rang Park, Seok-Jae Hwang, et al. “Accelerated platelet inhibition by switching from atorvastatin to a non-CYP3A4-metabolized statin in patients with high platelet reactivity (ACCEL-STATIN) study.” Eur Heart J 33, no. 17 (September 2012): 2151–62. https://doi.org/10.1093/eurheartj/ehs083.
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  - Jeong, Young-Hoon, Kevin P. Bliden, Yongwhi Park, Udaya S. Tantry, and Paul A. Gurbel. “Pharmacogenetic guidance for antiplatelet treatment.” Lancet 380, no. 9843 (August 25, 2012): 725. https://doi.org/10.1016/S0140-6736(12)61398-1.
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  - Antonino, Mark J., Young-Hoon Jeong, Udaya S. Tantry, Kevin P. Bliden, and Paul A. Gurbel. “Role of genotype-based personalized antiplatelet therapy in the era of potent P2Y₁₂ receptor inhibitors.” Expert Rev Cardiovasc Ther 10, no. 8 (August 2012): 1011–22. https://doi.org/10.1586/erc.12.1.
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  - Jeong, Young-Hoon, Udaya S. Tantry, and Paul A. Gurbel. “Importance of potent P2Y(12) receptor blockade in acute myocardial infarction: focus on prasugrel.” Expert Opin Pharmacother 13, no. 12 (August 2012): 1771–96. https://doi.org/10.1517/14656566.2012.704909.
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  - Gurbel, Paul A., Matthew T. Roe, Joseph A. Jakubowski, Svathi Shah, David Erlinge, Shaun G. Goodman, Kurt Huber, et al. “Translational platelet research in patients with coronary artery disease: what are the major knowledge gaps?” Thromb Haemost 108, no. 1 (July 2012): 12–20. https://doi.org/10.1160/TH12-01-0039.
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  - Jeong, Young-Hoon, Kevin P. Bliden, Mark J. Antonino, Ki-Soo Park, Udaya S. Tantry, and Paul A. Gurbel. “Usefulness of the VerifyNow P2Y12 assay to evaluate the antiplatelet effects of ticagrelor and clopidogrel therapies.” Am Heart J 164, no. 1 (July 2012): 35–42. https://doi.org/10.1016/j.ahj.2012.03.022.
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  - Reny, J. -. L., C. Combescure, Y. Daali, P. Fontana, and P. PON1 Meta-Analysis Group. “Influence of the paraoxonase-1 Q192R genetic variant on clopidogrel responsiveness and recurrent cardiovascular events: a systematic review and meta-analysis.” J Thromb Haemost 10, no. 7 (July 2012): 1242–51. https://doi.org/10.1111/j.1538-7836.2012.04756.x.
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  - Tantry, U. S., E. P. Navarese, J. Kubica, Y. H. Jeong, and P. A. Gurbel. “Ticagrelor in the treatment of coronary artery disease patients.” Clinical Practice 9, no. 4 (July 1, 2012): 373–90. https://doi.org/10.2217/cpr.12.40.
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  - Gurbel, Paul A., Thomas D. Nolin, and Udaya S. Tantry. “Clopidogrel efficacy and cigarette smoking status.” Jama 307, no. 23 (June 20, 2012): 2495–96. https://doi.org/10.1001/jama.2012.5930.
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  - Angiolillo, Dominick J., Robert C. Welsh, Dietmar Trenk, Franz-Josef Neumann, Pamela B. Conley, Matthew W. McClure, Gillian Stephens, et al. “Pharmacokinetic and pharmacodynamic effects of elinogrel: results of the platelet function substudy from the intravenous and oral administration of elinogrel to evaluate tolerability and efficacy in nonurgent percutaneous coronary intervention patients (INNOVATE-PCI) trial.” Circ Cardiovasc Interv 5, no. 3 (June 2012): 347–56. https://doi.org/10.1161/CIRCINTERVENTIONS.111.965608.
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  - Husted, Steen E., Robert F. Storey, Kevin Bliden, Udaya S. Tantry, Lene Høimark, Kathleen Butler, Cheryl Wei, Renli Teng, and Paul A. Gurbel. “Pharmacokinetics and pharmacodynamics of ticagrelor in patients with stable coronary artery disease: results from the ONSET-OFFSET and RESPOND studies.” Clin Pharmacokinet 51, no. 6 (June 1, 2012): 397–409. https://doi.org/10.2165/11599830-000000000-00000.
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  - Mahla, E., T. A. Suarez, K. P. Bliden, A. J. Sequeira, P. Cho, J. Sell, J. Fan, et al. “Response to letter regarding article, "platelet function measurement-based strategy to reduce bleeding and waiting time in clopidogrel-treated patients undergoing coronary artery bypass graft surgery: The timing based on platelet function strategy to reduce clopidogrel-associated bleeding related to CABG (TARGET-CABG) study".” Circulation: Cardiovascular Interventions 5, no. 3 (June 1, 2012). https://doi.org/10.1161/CIRCINTERVENTIONS.112.970301.
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  - Welsh, Robert C., Sunil V. Rao, Uwe Zeymer, Vivian P. Thompson, Kurt Huber, Janusz Kochman, Matthew W. McClure, et al. “A randomized, double-blind, active-controlled phase 2 trial to evaluate a novel selective and reversible intravenous and oral P2Y12 inhibitor elinogrel versus clopidogrel in patients undergoing nonurgent percutaneous coronary intervention: the INNOVATE-PCI trial.” Circ Cardiovasc Interv 5, no. 3 (June 2012): 336–46. https://doi.org/10.1161/CIRCINTERVENTIONS.111.964197.
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  - Gurbel, Paul A., E Magnus Ohman, Young-Hoon Jeong, and Udaya S. Tantry. “Toward a therapeutic window for antiplatelet therapy in the elderly.” Eur Heart J 33, no. 10 (May 2012): 1187–89. https://doi.org/10.1093/eurheartj/ehr458.
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  - Navarese, Eliano Pio, Antonino Buffon, Felicita Andreotti, Paul Alfred Gurbel, Marek Kozinski, Aldona Kubica, Giuseppe Musumeci, et al. “Adenosine improves post-procedural coronary flow but not clinical outcomes in patients with acute coronary syndrome: a meta-analysis of randomized trials.” Atherosclerosis 222, no. 1 (May 2012): 1–7. https://doi.org/10.1016/j.atherosclerosis.2011.11.001.
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  - Mahla, Elisabeth, Thomas A. Suarez, Kevin P. Bliden, Peter Rehak, Helfried Metzler, Alejandro J. Sequeira, Peter Cho, et al. “Platelet function measurement-based strategy to reduce bleeding and waiting time in clopidogrel-treated patients undergoing coronary artery bypass graft surgery: the timing based on platelet function strategy to reduce clopidogrel-associated bleeding related to CABG (TARGET-CABG) study.” Circ Cardiovasc Interv 5, no. 2 (April 2012): 261–69. https://doi.org/10.1161/CIRCINTERVENTIONS.111.967208.
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  - Tantry, U. S., E. P. Navarese, and P. A. Gurbel. “Does gender have an influence on platelet function and the efficacy of oral antiplatelet therapy?” Interventional Cardiology Clinics 1, no. 2 (April 1, 2012): 223–30. https://doi.org/10.1016/j.iccl.2012.01.007.
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  - Gurbel, Paul A., and Udaya S. Tantry. “Do platelet function testing and genotyping improve outcome in patients treated with antithrombotic agents?: platelet function testing and genotyping improve outcome in patients treated with antithrombotic agents.” Circulation 125, no. 10 (March 13, 2012): 1276–87. https://doi.org/10.1161/CIRCULATIONAHA.111.031195.
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  - Jeong, Y. -. H., K. P. Bliden, U. S. Tantry, and P. A. Gurbel. “High on-treatment platelet reactivity assessed by various platelet function tests: is the consensus-defined cut-off of VASP-P platelet reactivity index too low?” J Thromb Haemost 10, no. 3 (March 2012): 487–89. https://doi.org/10.1111/j.1538-7836.2011.04604.x.
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  - Tantry, Udaya S., Young-Hoon Jeong, Eliano P. Navarese, and Paul A. Gurbel. “Platelet function measurement in elective percutaneous coronary intervention patients: exploring the concept of a P2Y₁₂ inhibitor therapeutic window.” Jacc Cardiovasc Interv 5, no. 3 (March 2012): 290–92. https://doi.org/10.1016/j.jcin.2012.01.007.
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  - Jeong, Young-Hoon, Yongwhi Park, Kevin P. Bliden, Udaya S. Tantry, and Paul A. Gurbel. “High platelet reactivity to multiple agonists during aspirin and clopidogrel treatment is indicative of a global hyperreactive platelet phenotype.” Heart 98, no. 4 (February 2012): 343. https://doi.org/10.1136/heartjnl-2011-301129.
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  - Gurbel, Paul A., Kevin P. Bliden, Mark J. Antonino, Tania Gesheff, Charles C. Cummings, Benjamin V. Dubois, William R. Herzog, and Udaya S. Tantry. “Time dependence of clopidogrel loading effect: platelet activation versus platelet aggregation.” Thromb Res 129, no. 1 (January 2012): 1–2. https://doi.org/10.1016/j.thromres.2011.07.048.
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  - Kubica, Jacek, Marek Koziński, Eliano P. Navarese, Udaya S. Tantry, Grzegorz Grześk, Tomasz Fabiszak, Aldona Kubica, Iwona Świątkiewicz, Kevin P. Bliden, and Paul A. Gurbel. “Updated evidence on intracoronary abciximab in ST-elevation myocardial infarction: a systematic review and meta-analysis of randomized clinical trials.” Cardiol J 19, no. 3 (2012): 230–42. https://doi.org/10.5603/cj.2012.0044.
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  - Navarese, Eliano Pio, Marek Kozinski, Karolina Obonska, Massimo Margheri, Paul Alfred Gurbel, Jacek Kubica, and Giuseppe De Luca. “Clinical efficacy and safety of intracoronary vs. intravenous abciximab administration in STEMI patients undergoing primary percutaneous coronary intervention: a meta-analysis of randomized trials.” Platelets 23, no. 4 (2012): 274–81. https://doi.org/10.3109/09537104.2011.619602.
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  - Tantry, Udaya S., Andrzej Budaj, and Paul A. Gurbel. “Antiplatelet therapy beyond 2012: role of personalized medicine.” Pol Arch Med Wewn 122, no. 6 (2012): 298–305.
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  - Jeong, Young-Hoon, Kevin P. Bliden, Udaya S. Tantry, and Paul A. Gurbel. “The role of platelet function testing and genotyping in the stented patient treated with clopidogrel.” J Am Coll Cardiol 58, no. 25 (December 13, 2011): 2701–2. https://doi.org/10.1016/j.jacc.2011.08.059.
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  - Gurbel, P. A., K. P. Bliden, J. Fort, Y. Zhang, J. R. Plachetka, M. Antonino, M. Gesheff, and U. S. Tantry. “Pharmacodynamic evaluation of clopidogrel plus PA32540: the Spaced PA32540 With Clopidogrel Interaction Gauging (SPACING) study.” Clin Pharmacol Ther 90, no. 6 (December 2011): 860–66. https://doi.org/10.1038/clpt.2011.201.
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  - Jeong, Young-Hoon, Udaya S. Tantry, In-Suk Kim, Jin-Sin Koh, Tae Jung Kwon, Yongwhi Park, Seok-Jae Hwang, et al. “Effect of CYP2C19*2 and *3 loss-of-function alleles on platelet reactivity and adverse clinical events in East Asian acute myocardial infarction survivors treated with clopidogrel and aspirin.” Circ Cardiovasc Interv 4, no. 6 (December 1, 2011): 585–94. https://doi.org/10.1161/CIRCINTERVENTIONS.111.962555.
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  - Navarese, Eliano Pio, Jacek Kubica, and Paul A. Gurbel. “"Sirolimus or paclitaxel drug eluting stent in left main disease: the winner is... ".” Int J Cardiol 152, no. 3 (November 3, 2011): 387. https://doi.org/10.1016/j.ijcard.2011.08.024.
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  - Gurbel, Paul A., Young-Hoon Jeong, and Udaya S. Tantry. “Vorapaxar: a novel protease-activated receptor-1 inhibitor.” Expert Opin Investig Drugs 20, no. 10 (October 2011): 1445–53. https://doi.org/10.1517/13543784.2011.606809.
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  - Lewis, J. P., A. S. Fisch, K. Ryan, J. R. O’Connell, Q. Gibson, B. D. Mitchell, H. Shen, et al. “Paraoxonase 1 (PON1) gene variants are not associated with clopidogrel response.” Clin Pharmacol Ther 90, no. 4 (October 2011): 568–74. https://doi.org/10.1038/clpt.2011.194.
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  - Navarese, E. P., G. De Luca, F. Castriota, M. Kozinski, P. A. Gurbel, C. M. Gibson, F. Andreotti, et al. “Low-molecular-weight heparins vs. unfractionated heparin in the setting of percutaneous coronary intervention for ST-elevation myocardial infarction: a meta-analysis.” J Thromb Haemost 9, no. 10 (October 2011): 1902–15. https://doi.org/10.1111/j.1538-7836.2011.04445.x.
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  - Gurbel, Paul A., Young-Hoon Jeong, and Udaya S. Tantry. “Cutaneous clopidogrel hypersensitivity: give steroids and do not stop the clopidogrel.” J Am Coll Cardiol 58, no. 14 (September 27, 2011): 1455–56. https://doi.org/10.1016/j.jacc.2011.06.036.
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  - Storey, R. F., K. P. Bliden, R. Ecob, A. Karunakaran, K. Butler, C. Wei, U. Tantry, and P. A. Gurbel. “Earlier recovery of platelet function after discontinuation of treatment with ticagrelor compared with clopidogrel in patients with high antiplatelet responses.” J Thromb Haemost 9, no. 9 (September 2011): 1730–37. https://doi.org/10.1111/j.1538-7836.2011.04419.x.
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  - Gurbel, Paul A., Elisabeth Mahla, and Udaya S. Tantry. “Peri-operative platelet function testing: the potential for reducing ischaemic and bleeding risks.” Thromb Haemost 106, no. 2 (August 2011): 248–52. https://doi.org/10.1160/TH11-02-0063.
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  - Gurbel, Paul A., Udaya S. Tantry, Kevin P. Bliden, and Young-Hoon Jeong. “Immunity to thrombotic events is achievable if we stop the guessing game: is this the major hidden message from GRAVITAS?” Thromb Haemost 106, no. 2 (August 2011): 263–64. https://doi.org/10.1160/TH11-02-0064.
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  - Gurbel, Paul A., and Udaya S. Tantry. “Clopidogrel response variability and the advent of personalised antiplatelet therapy. A bench to bedside journey.” Thromb Haemost 106, no. 2 (August 2011): 265–71. https://doi.org/10.1160/TH11-03-0167.
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  - Tantry, Udaya S., and Paul A. Gurbel. “Assessment of oral antithrombotic therapy by platelet function testing.” Nat Rev Cardiol 8, no. 10 (July 19, 2011): 572–79. https://doi.org/10.1038/nrcardio.2011.107.
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  - Jeong, Young-Hoon, Kevin P. Bliden, Udaya S. Tantry, In-Suk Kim, Yongwhi Park, and Paul A. Gurbel. “We need further studies for the development of "optimized antiplatelet therapy" based on ethnicity.” J Am Coll Cardiol 58, no. 2 (July 5, 2011): 198. https://doi.org/10.1016/j.jacc.2011.02.048.
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  - Bliden, Kevin P., Udaya S. Tantry, Robert F. Storey, Young-Hoon Jeong, Martin Gesheff, Cheryl Wei, and Paul A. Gurbel. “The effect of ticagrelor versus clopidogrel on high on-treatment platelet reactivity: combined analysis of the ONSET/OFFSET and RESPOND studies.” Am Heart J 162, no. 1 (July 2011): 160–65. https://doi.org/10.1016/j.ahj.2010.11.025.
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  - Jeong, Young-Hoon, Kevin P. Bliden, Udaya S. Tantry, and Paul A. Gurbel. “Do East Asians have different hypercoagulable states compared with Western population?” Am Heart J 162, no. 1 (July 2011): e19–20. https://doi.org/10.1016/j.ahj.2011.05.001.
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  - Kandzari, David E., Laura Mauri, Jeffrey J. Popma, Mark A. Turco, Paul A. Gurbel, Peter J. Fitzgerald, and Martin B. Leon. “Late-term clinical outcomes with zotarolimus- and sirolimus-eluting stents. 5-year follow-up of the ENDEAVOR III (A Randomized Controlled Trial of the Medtronic Endeavor Drug [ABT-578] Eluting Coronary Stent System Versus the Cypher Sirolimus-Eluting Coronary Stent System in De Novo Native Coronary Artery Lesions).” Jacc Cardiovasc Interv 4, no. 5 (May 2011): 543–50. https://doi.org/10.1016/j.jcin.2010.12.014.
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  - Bliden, Kevin P., Udaya S. Tantry, Joseph DiChiara, and Paul A. Gurbel. “Further ex vivo evidence supporting higher aspirin dosing in patients with coronary artery disease and diabetes.” Circ Cardiovasc Interv 4, no. 2 (April 1, 2011): 118–20. https://doi.org/10.1161/CIRCINTERVENTIONS.111.961847.
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  - Tantry, Udaya S., Dean J. Kereiakes, and Paul A. Gurbel. “Clopidogrel and proton pump inhibitors: influence of pharmacological interactions on clinical outcomes and mechanistic explanations.” Jacc Cardiovasc Interv 4, no. 4 (April 2011): 365–80. https://doi.org/10.1016/j.jcin.2010.12.009.
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  - Gurbel, Paul A., and Udaya S. Tantry. “An initial experiment with personalized antiplatelet therapy: the GRAVITAS trial.” Jama 305, no. 11 (March 16, 2011): 1136–37. https://doi.org/10.1001/jama.2011.332.
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  - Gurbel, Paul A., Alan R. Shuldiner, Kevin P. Bliden, Kathaleen Ryan, Ruth E. Pakyz, and Udaya S. Tantry. “The relation between CYP2C19 genotype and phenotype in stented patients on maintenance dual antiplatelet therapy.” Am Heart J 161, no. 3 (March 2011): 598–604. https://doi.org/10.1016/j.ahj.2010.12.011.
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  - Bergmeijer, T. O., J. W. van Werkum, U. S. Tantry, P. A. Gurbel, and J. M. ten Berg. “Platelet Function Testing in Clinical Practice - Experience and Views from Europe and the US.” European Cardiology 7, no. 3 (January 1, 2011): 203–11. https://doi.org/10.15420/ecr.2011.7.3.203.
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  - Gurbel, Paul A., and Udaya S. Tantry. “Antiplatelet therapy: Clopidogrel-PPI interaction, an ongoing controversy.” Nat Rev Cardiol 8, no. 1 (January 2011): 7–8. https://doi.org/10.1038/nrcardio.2010.185.
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  - Jeong, Young-Hoon, Udaya S. Tantry, Kevin P. Bliden, and Paul A. Gurbel. “Cilostazol to overcome high on-treatment platelet reactivity in korean patients treated with clopidogrel and calcium-channel blocker.” Circ J 75, no. 11 (2011): 2534–36. https://doi.org/10.1253/circj.cj-11-1076.
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  - Lau, Wei C., Terrence D. Welch, Theresa Shields, Melvyn Rubenfire, Udaya S. Tantry, and Paul A. Gurbel. “The effect of St John's Wort on the pharmacodynamic response of clopidogrel in hyporesponsive volunteers and patients: increased platelet inhibition by enhancement of CYP3A4 metabolic activity.” J Cardiovasc Pharmacol 57, no. 1 (January 2011): 86–93. https://doi.org/10.1097/FJC.0b013e3181ffe8d0.
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  - Price, Matthew J., Udaya S. Tantry, and Paul A. Gurbel. “The influence of CYP2C19 polymorphisms on the pharmacokinetics, pharmacodynamics, and clinical effectiveness of P2Y(12) inhibitors.” Rev Cardiovasc Med 12, no. 1 (2011): 1–12. https://doi.org/10.3909/ricm0590.
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  - Tantry, Udaya S., and Paul A. Gurbel. “Current options in oral antiplatelet strategies during percutaneous coronary interventions.” Rev Cardiovasc Med 12 Suppl 1 (2011): S4-13.
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  - Tantry, Udaya S., Kevin P. Bliden, Cheryl Wei, Robert F. Storey, Martin Armstrong, Kathleen Butler, and Paul A. Gurbel. “First analysis of the relation between CYP2C19 genotype and pharmacodynamics in patients treated with ticagrelor versus clopidogrel: the ONSET/OFFSET and RESPOND genotype studies.” Circ Cardiovasc Genet 3, no. 6 (December 2010): 556–66. https://doi.org/10.1161/CIRCGENETICS.110.958561.
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  - Antonino, Mark J., Rosa Coppolecchia, Elisabeth Mahla, Kevin P. Bliden, Udaya S. Tantry, and Paul A. Gurbel. “Antiplatelet effects of aspirin with phytosterols: comparison with non-enteric coated aspirin alone.” Thromb Res 126, no. 5 (November 2010): 384–85. https://doi.org/10.1016/j.thromres.2009.05.003.
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  - Gurbel, P. A., D. Kereiakes, and U. S. Tantry. “Elinogrel potassium: Receptor antagonist antiplatelet therapy.” Drugs of the Future 35, no. 11 (November 1, 2010): 885–92. https://doi.org/10.1358/dof.2010.35.11.1529823.
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  - Mega, Jessica L., Tabassome Simon, Jean-Philippe Collet, Jeffrey L. Anderson, Elliott M. Antman, Kevin Bliden, Christopher P. Cannon, et al. “Reduced-function CYP2C19 genotype and risk of adverse clinical outcomes among patients treated with clopidogrel predominantly for PCI: a meta-analysis.” Jama 304, no. 16 (October 27, 2010): 1821–30. https://doi.org/10.1001/jama.2010.1543.
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  - Gurbel, Paul A., Udaya S. Tantry, and Alan R. Shuldiner. “Letter by Gurbel et al regarding article, "Cytochrome 2C19*17 allelic variant, platelet aggregation, bleeding events, and stent thrombosis in clopidogrel-treated patients with coronary stent placement".” Circulation 122, no. 14 (October 5, 2010): e478. https://doi.org/10.1161/CIRCULATIONAHA.110.943548.
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  - Gurbel, Paul A., and Udaya S. Tantry. “Acceptance of high platelet reactivity as a risk factor: now, what do we do about it?” Jacc Cardiovasc Interv 3, no. 10 (October 2010): 1008–10. https://doi.org/10.1016/j.jcin.2010.08.011.
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  - Angiolillo, Dominick J., Jorge F. Saucedo, Roger Deraad, Andrew L. Frelinger, Paul A. Gurbel, Timothy M. Costigan, Joseph A. Jakubowski, Clement K. Ojeh, Mark B. Effron, and Mark B. SWAP Investigators. “Increased platelet inhibition after switching from maintenance clopidogrel to prasugrel in patients with acute coronary syndromes: results of the SWAP (SWitching Anti Platelet) study.” J Am Coll Cardiol 56, no. 13 (September 21, 2010): 1017–23. https://doi.org/10.1016/j.jacc.2010.02.072.
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  - Bonello, Laurent, Udaya S. Tantry, Rossella Marcucci, Ruediger Blindt, Dominick J. Angiolillo, Richard Becker, Deepak L. Bhatt, et al. “Consensus and future directions on the definition of high on-treatment platelet reactivity to adenosine diphosphate.” J Am Coll Cardiol 56, no. 12 (September 14, 2010): 919–33. https://doi.org/10.1016/j.jacc.2010.04.047.
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  - Gurbel, Paul A., Dean J. Kereiakes, and Udaya S. Tantry. “Ticagrelor for the treatment of arterial thrombosis.” Expert Opin Pharmacother 11, no. 13 (September 2010): 2251–59. https://doi.org/10.1517/14656566.2010.511175.
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  - Mahla, Elisabeth, Helfried Metzler, Udaya S. Tantry, and Paul A. Gurbel. “Controversies in oral antiplatelet therapy in patients undergoing aortocoronary bypass surgery.” Ann Thorac Surg 90, no. 3 (September 2010): 1040–51. https://doi.org/10.1016/j.athoracsur.2010.04.041.
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  - Gurbel, Paul A., Kevin P. Bliden, Irene A. Navickas, Elizabeth Mahla, Joseph Dichiara, Thomas A. Suarez, Mark J. Antonino, Udaya S. Tantry, and Eli Cohen. “Adenosine diphosphate-induced platelet-fibrin clot strength: a new thrombelastographic indicator of long-term poststenting ischemic events.” Am Heart J 160, no. 2 (August 2010): 346–54. https://doi.org/10.1016/j.ahj.2010.05.034.
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  - Storey, Robert F., Kevin P. Bliden, Shankar B. Patil, Arun Karunakaran, Rosemary Ecob, Kathleen Butler, Renli Teng, et al. “Incidence of dyspnea and assessment of cardiac and pulmonary function in patients with stable coronary artery disease receiving ticagrelor, clopidogrel, or placebo in the ONSET/OFFSET study.” J Am Coll Cardiol 56, no. 3 (July 13, 2010): 185–93. https://doi.org/10.1016/j.jacc.2010.01.062.
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  - Gurbel, Paul A., Udaya S. Tantry, Alan R. Shuldiner, and Dean J. Kereiakes. “Genotyping: one piece of the puzzle to personalize antiplatelet therapy.” J Am Coll Cardiol 56, no. 2 (July 6, 2010): 112–16. https://doi.org/10.1016/j.jacc.2010.04.008.
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  - Hennekens, Charles H., Wendy R. Schneider, Patricia R. Hebert, Udaya S. Tantry, and Paul A. Gurbel. “Hypothesis formulation from subgroup analyses: nonadherence or nonsteroidal anti-inflammatory drug use explains the lack of clinical benefit of aspirin on first myocardial infarction attributed to "aspirin resistance".” Am Heart J 159, no. 5 (May 2010): 744–48. https://doi.org/10.1016/j.ahj.2009.11.033.
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  - Gurbel, Paul A., Kevin P. Bliden, Kathleen Butler, Mark J. Antonino, Cheryl Wei, Renli Teng, Lars Rasmussen, et al. “Response to ticagrelor in clopidogrel nonresponders and responders and effect of switching therapies: the RESPOND study.” Circulation 121, no. 10 (March 16, 2010): 1188–99. https://doi.org/10.1161/CIRCULATIONAHA.109.919456.
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  - Becker, Richard C., and Paul A. Gurbel. “Platelet P2Y12 receptor antagonist pharmacokinetics and pharmacodynamics: A foundation for distinguishing mechanisms of bleeding and anticipated risk for platelet-directed therapies.” Thromb Haemost 103, no. 3 (March 2010): 535–44. https://doi.org/10.1160/TH09-07-0491.
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  - Gurbel, P. “Aspirin - Scope and limitations.” British Journal of Cardiology 17, no. SUPPL. 1 (March 1, 2010).
  - Gurbel, Paul A., and Udaya S. Tantry. “Delivery of glycoprotein IIb/IIIa inhibitor therapy for percutaneous coronary intervention: why not take the intracoronary highway?” Circulation 121, no. 6 (February 16, 2010): 739–41. https://doi.org/10.1161/CIR.0b013e3181d40dc9.
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  - Gurbel, Paul A., and Udaya S. Tantry. “Combination antithrombotic therapies.” Circulation 121, no. 4 (February 2, 2010): 569–83. https://doi.org/10.1161/CIRCULATIONAHA.109.853085.
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  - Gurbel, P. A., K. P. Bliden, M. J. Antonino, G. Stephens, D. D. Gretler, M. M. Jurek, R. E. Pakyz, A. R. Shuldiner, P. B. Conley, and U. S. Tantry. “The effect of elinogrel on high platelet reactivity during dual antiplatelet therapy and the relation to CYP2C19*2 genotype: first experience in patients.” J Thromb Haemost 8, no. 1 (January 2010): 43–53. https://doi.org/10.1111/j.1538-7836.2009.03648.x.
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  - Gurbel, Paul A., Udaya S. Tantry, and Dean J. Kereiakes. “Interaction between clopidogrel and proton-pump inhibitors and management strategies in patients with cardiovascular diseases.” Drug Healthc Patient Saf 2 (2010): 233–40. https://doi.org/10.2147/DHPS.S7297.
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  - Tantry, Udaya S., Kevin P. Bliden, Thomas A. Suarez, Rolf P. Kreutz, Joseph Dichiara, and Paul A. Gurbel. “Hypercoagulability, platelet function, inflammation and coronary artery disease acuity: results of the Thrombotic RIsk Progression (TRIP) study.” Platelets 21, no. 5 (2010): 360–67. https://doi.org/10.3109/09537100903548903.
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  - Gurbel, Paul A., Kevin P. Bliden, Kathleen Butler, Udaya S. Tantry, Tania Gesheff, Cheryl Wei, Renli Teng, et al. “Randomized double-blind assessment of the ONSET and OFFSET of the antiplatelet effects of ticagrelor versus clopidogrel in patients with stable coronary artery disease: the ONSET/OFFSET study.” Circulation 120, no. 25 (December 22, 2009): 2577–85. https://doi.org/10.1161/CIRCULATIONAHA.109.912550.
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  - Gurbel, Paul A., Udaya S. Tantry, and Alan R. Shuldiner. “The worry about clopidogrel "nonresponsiveness": identification and treatment in the post-percutaneous coronary intervention patient.” Jacc Cardiovasc Interv 2, no. 11 (November 2009): 1102–4. https://doi.org/10.1016/j.jcin.2009.09.005.
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  - Singla, Anand, Mark J. Antonino, Kevin P. Bliden, Udaya S. Tantry, and Paul A. Gurbel. “The relation between platelet reactivity and glycemic control in diabetic patients with cardiovascular disease on maintenance aspirin and clopidogrel therapy.” Am Heart J 158, no. 5 (November 2009): 784.e1-784.e6. https://doi.org/10.1016/j.ahj.2009.08.013.
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  - Tantry, U. S., and P. A. Gurbel. “Platelet monitoring for PCI: is it really necessary?” Hamostaseologie 29, no. 4 (November 2009): 368–75.
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  - Tantry, Udaya S., Elisabeth Mahla, and Paul A. Gurbel. “Aspirin resistance.” Prog Cardiovasc Dis 52, no. 2 (September 2009): 141–52. https://doi.org/10.1016/j.pcad.2009.05.001.
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  - Shuldiner, Alan R., Jeffrey R. O’Connell, Kevin P. Bliden, Amish Gandhi, Kathleen Ryan, Richard B. Horenstein, Coleen M. Damcott, et al. “Association of cytochrome P450 2C19 genotype with the antiplatelet effect and clinical efficacy of clopidogrel therapy.” Jama 302, no. 8 (August 26, 2009): 849–57. https://doi.org/10.1001/jama.2009.1232.
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  - Pinto Slottow, Tina L., Laurent Bonello, Rekha Gavini, Patricia Beauzile, Steven J. Sushinsky, Mickey Scheinowitz, Kimberly Kaneshige, et al. “Prevalence of aspirin and clopidogrel resistance among patients with and without drug-eluting stent thrombosis.” Am J Cardiol 104, no. 4 (August 15, 2009): 525–30. https://doi.org/10.1016/j.amjcard.2009.04.015.
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  - Gurbel, Paul A., Mark J. Antonino, and Udaya S. Tantry. “Recent developments in clopidogrel pharmacology and their relation to clinical outcomes.” Expert Opin Drug Metab Toxicol 5, no. 8 (August 2009): 989–1004. https://doi.org/10.1517/17425250903107772.
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  - Hoekstra, James, Marc Cohen, Robert Giugliano, Christopher B. Granger, Paul A. Gurbel, Judd E. Hollander, Steven V. Manoukian, Jorge F. Saucedo, and Charles V. Pollack. “Expert consensus on treatment strategies in non- ST-segment elevation acute coronary syndromes in patients undergoing percutaneous coronary intervention--an evidence-based review of clinical trial results and treatment guidelines from an emergency medicine perspective: report on a roundtable discussion.” Am J Emerg Med 27, no. 6 (July 2009): 720–28. https://doi.org/10.1016/j.ajem.2008.04.032.
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  - Antonino, Mark J., Elisabeth Mahla, Kevin P. Bliden, Udaya S. Tantry, and Paul A. Gurbel. “Effect of long-term clopidogrel treatment on platelet function and inflammation in patients undergoing coronary arterial stenting.” Am J Cardiol 103, no. 11 (June 1, 2009): 1546–50. https://doi.org/10.1016/j.amjcard.2009.01.367.
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  - Gurbel, Paul A., Elisabeth Mahla, Mark J. Antonino, and Udaya S. Tantry. “Response variability and the role of platelet function testing.” J Invasive Cardiol 21, no. 4 (April 2009): 172–78.
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  - Lau, Wei C., and Paul A. Gurbel. “The drug-drug interaction between proton pump inhibitors and clopidogrel.” Cmaj 180, no. 7 (March 31, 2009): 699–700. https://doi.org/10.1503/cmaj.090251.
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  - Mahla, Elisabeth, Mark J. Antonino, Udaya S. Tantry, and Paul A. Gurbel. “Point-of-care platelet function analysis ready for prime time?” J Am Coll Cardiol 53, no. 10 (March 10, 2009): 857–59. https://doi.org/10.1016/j.jacc.2008.11.033.
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  - Gilstad, John R., Paul A. Gurbel, and Ross E. Andersen. “Relationship between age and platelet activation in patients with stable and unstable angina.” Arch Gerontol Geriatr 48, no. 2 (March 2009): 155–59. https://doi.org/10.1016/j.archger.2007.12.006.
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  - Gurbel, Paul A., Kevin P. Bliden, Rolf P. Kreutz, Joseph Dichiara, Mark J. Antonino, and Udaya S. Tantry. “The link between heightened thrombogenicity and inflammation: pre-procedure characterization of the patient at high risk for recurrent events after stenting.” Platelets 20, no. 2 (March 2009): 97–104. https://doi.org/10.1080/09537100802687666.
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  - Hamed, M. S., S. Gambert, K. P. Bliden, O. Bailon, A. Singla, M. J. Antonino, F. Hamed, U. S. Tantry, and P. A. Gurbel. “Dark chocolate effect on platelet activity, C-reactive protein and lipid profile: A pilot study Southern Medical Journal (2008) 101, (1203-1208)).” Southern Medical Journal 102, no. 3 (March 1, 2009): 332. https://doi.org/10.1097/SMJ.0b013e318182f392.
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  - Gurbel, Paul A., Kevin P. Bliden, Jorge F. Saucedo, Thomas A. Suarez, Joseph DiChiara, Mark J. Antonino, Elisabeth Mahla, et al. “Bivalirudin and clopidogrel with and without eptifibatide for elective stenting: effects on platelet function, thrombelastographic indexes, and their relation to periprocedural infarction results of the CLEAR PLATELETS-2 (Clopidogrel with Eptifibatide to Arrest the Reactivity of Platelets) study.” J Am Coll Cardiol 53, no. 8 (February 24, 2009): 648–57. https://doi.org/10.1016/j.jacc.2008.10.045.
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  - Angiolillo, Dominick J., Deepak L. Bhatt, Paul A. Gurbel, and Lisa K. Jennings. “Advances in antiplatelet therapy: agents in clinical development.” Am J Cardiol 103, no. 3 Suppl (February 2, 2009): 40A-51A. https://doi.org/10.1016/j.amjcard.2008.11.023.
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  - Gurbel, Paul A., and Udaya S. Tantry. “Selecting optimal antiplatelet therapy based on platelet function monitoring in patients with coronary artery disease.” Curr Treat Options Cardiovasc Med 11, no. 1 (February 2009): 22–32. https://doi.org/10.1007/s11936-009-0003-y.
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  - Gurbel, Paul A., and Udaya S. Tantry. “Antiplatelet resistance--fact or myth?” Am Heart Hosp J 7, no. 1 (2009): 50–57. https://doi.org/10.15420/ahhj.2009.7.1.50.
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  - Gurbel, Paul A., Mark J. Antonino, Kevin P. Bliden, Joseph Dichiara, Thomas A. Suarez, Anand Singla, and Udaya S. Tantry. “Platelet reactivity to adenosine diphosphate and long-term ischemic event occurrence following percutaneous coronary intervention: a potential antiplatelet therapeutic target.” Platelets 19, no. 8 (December 2008): 595–604. https://doi.org/10.1080/09537100802351065.
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  - Gurbel, Paul A., and Udaya S. Tantry. “The rationale for and comparisons of different antiplatelet treatments in acute coronary syndrome.” J Interv Cardiol 21 Suppl 1 (December 2008): S10–17. https://doi.org/10.1111/j.1540-8183.2008.00408.x.
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  - Hamed, Miruais S., Steven Gambert, Kevin P. Bliden, Oscar Bailon, Anand Singla, Mark J. Antonino, Fatema Hamed, Udaya S. Tantry, and Paul A. Gurbel. “Dark chocolate effect on platelet activity, C-reactive protein and lipid profile: a pilot study.” South Med J 101, no. 12 (December 2008): 1203–8. https://doi.org/10.1097/SMJ.0b013e31818859eb.
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  - Bliden, Kevin P., Joseph Dichiara, Lookman Lawal, Anand Singla, Mark J. Antonino, Brian A. Baker, William L. Bailey, Udaya S. Tantry, and Paul A. Gurbel. “The association of cigarette smoking with enhanced platelet inhibition by clopidogrel.” J Am Coll Cardiol 52, no. 7 (August 12, 2008): 531–33. https://doi.org/10.1016/j.jacc.2008.04.045.
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  - Cohen, Marc, James Hoekstra, Robert Giugliano, Christopher B. Granger, Paul A. Gurbel, Judd E. Hollander, Steven V. Manoukian, Charles V. Pollack, and Jorge F. Saucedo. “Treatment strategies in non-ST-elevation acute coronary syndromes in patients undergoing percutaneous coronary intervention: an evidence-based review of clinical trial results and treatment guidelines: report on a roundtable discussion.” J Interv Cardiol 21, no. 4 (August 2008): 283–99. https://doi.org/10.1111/j.1540-8183.2008.00375.x.
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  - Gurbel, Paul A., Kevin P. Bliden, Eli Cohen, Irene A. Navickas, Anand Singla, Mark J. Antonino, Mulugeta Fissha, Rolf P. Kreutz, Ashwani K. Bassi, and Udaya S. Tantry. “Race and sex differences in thrombogenicity: risk of ischemic events following coronary stenting.” Blood Coagul Fibrinolysis 19, no. 4 (June 2008): 268–75. https://doi.org/10.1097/MBC.0b013e3282ff76ae.
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  - Dichiara, J., K. P. Bliden, U. S. Tantry, M. S. Hamed, M. J. Antonino, T. A. Suarez, O. Bailon, A. Singla, and P. A. Gurbel. “Response to comment on: dichiara et al. (2007) the effect of aspirin dosing on platelet function in diabetic and nondiabetic patients: an analysis from the aspirin-induced platelet effect (ASPECT) study: Diabetes 56:3014-3019, 2007.” Diabetes 57, no. 5 (May 1, 2008). https://doi.org/10.2337/db08-0250.
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  - Gurbel, Paul A., Mark J. Antonino, and Udaya S. Tantry. “Antiplatelet treatment of cardiovascular disease: a translational research perspective.” Pol Arch Med Wewn 118, no. 5 (May 2008): 289–97.
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  - Kereiakes, Dean J., and Paul A. Gurbel. “Peri-procedural platelet function and platelet inhibition in percutaneous coronary intervention.” Jacc Cardiovasc Interv 1, no. 2 (April 2008): 111–21. https://doi.org/10.1016/j.jcin.2008.01.005.
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  - Braunwald, Eugene, Dominick Angiolillo, Eric Bates, Peter B. Berger, Deepak Bhatt, Christopher P. Cannon, Mark I. Furman, et al. “Clinical considerations with the use of antiplatelet therapy in patients undergoing percutaneous coronary intervention.” Clin Cardiol 31, no. 3 Suppl 1 (March 2008): I28–35. https://doi.org/10.1002/clc.20359.
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  - Braunwald, Eugene, Dominick Angiolillo, Eric Bates, Peter B. Berger, Deepak Bhatt, Christopher P. Cannon, Mark I. Furman, et al. “Antiplatelet strategies: evaluating their current role in the setting of acute coronary syndromes.” Clin Cardiol 31, no. 3 Suppl 1 (March 2008): I2–9. https://doi.org/10.1002/clc.20362.
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  - Braunwald, Eugene, Dominick Angiolillo, Eric Bates, Peter B. Berger, Deepak Bhatt, Christopher P. Cannon, Mark I. Furman, et al. “Antiplatelet therapy and platelet function testing. Introduction.” Clin Cardiol 31, no. 3 Suppl 1 (March 2008): I1. https://doi.org/10.1002/clc.20370.
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  - Braunwald, Eugene, Dominick Angiolillo, Eric Bates, Peter B. Berger, Deepak Bhatt, Christopher P. Cannon, Mark I. Furman, et al. “The problem of persistent platelet activation in acute coronary syndromes and following percutaneous coronary intervention.” Clin Cardiol 31, no. 3 Suppl 1 (March 2008): I17–20. https://doi.org/10.1002/clc.20363.
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  - Braunwald, Eugene, Dominick Angiolillo, Eric Bates, Peter B. Berger, Deepak Bhatt, Christopher P. Cannon, Mark I. Furman, et al. “Investigating the mechanisms of hyporesponse to antiplatelet approaches.” Clin Cardiol 31, no. 3 Suppl 1 (March 2008): I21–27. https://doi.org/10.1002/clc.20360.
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  - Braunwald, Eugene, Dominick Angiolillo, Eric Bates, Peter B. Berger, Deepak Bhatt, Christopher P. Cannon, Mark I. Furman, et al. “Assessing the current role of platelet function testing.” Clin Cardiol 31, no. 3 Suppl 1 (March 2008): I10–16. https://doi.org/10.1002/clc.20361.
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  - Gurbel, Paul A., and Udaya S. Tantry. “Prasugrel, a third generation thienopyridine and potent platelet inhibitor.” Curr Opin Investig Drugs 9, no. 3 (March 2008): 324–36.
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  - Gurbel, P. A., K. P. Bliden, J. Dichiara, T. Gesheff, S. K. Chaganti, A. Etherington, U. S. Tantry, J. Newcomer, W. Weng, and N. K. Neerchal. “Response to the letter regarding article, "Evaluation of dose-related effects of aspirin on platelet function: Results From the Aspirin-Induced Platelet Effect (ASPECT) study".” Circulation 117, no. 4 (January 29, 2008). https://doi.org/10.1161/CIRCULATIONAHA.107.740928.
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  - Gurbel, Paul A., Wei C. Lau, and Udaya S. Tantry. “Omeprazole: a possible new candidate influencing the antiplatelet effect of clopidogrel.” J Am Coll Cardiol 51, no. 3 (January 22, 2008): 261–63. https://doi.org/10.1016/j.jacc.2007.07.090.
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  - Gurbel, Paul A., Kevin P. Bilden, and Udaya S. Tantry. “Diagnostics for aspirin resistance.” Mol Diagn Ther 12, no. 1 (2008): 55–56. https://doi.org/10.1007/BF03256269.
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  - Gurbel, Paul A., Rolf P. Kreutz, Kevin P. Bliden, Joseph DiChiara, and Udaya S. Tantry. “Biomarker analysis by fluorokine multianalyte profiling distinguishes patients requiring intervention from patients with long-term quiescent coronary artery disease: a potential approach to identify atherosclerotic disease progression.” Am Heart J 155, no. 1 (January 2008): 56–61. https://doi.org/10.1016/j.ahj.2007.08.021.
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  - DiChiara, Joseph, Kevin P. Bliden, Udaya S. Tantry, Miruais S. Hamed, Mark J. Antonino, Thomas A. Suarez, Oscar Bailon, Anand Singla, and Paul A. Gurbel. “The effect of aspirin dosing on platelet function in diabetic and nondiabetic patients: an analysis from the aspirin-induced platelet effect (ASPECT) study.” Diabetes 56, no. 12 (December 2007): 3014–19. https://doi.org/10.2337/db07-0707.
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  - Kreutz, Rolf P., Udaya S. Tantry, Kevin P. Bliden, and Paul A. Gurbel. “Inflammatory changes during the 'common cold' are associated with platelet activation and increased reactivity of platelets to agonists.” Blood Coagul Fibrinolysis 18, no. 8 (December 2007): 713–18. https://doi.org/10.1097/MBC.0b013e328201c77e.
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  - Gurbel, Paul A., Richard C. Becker, Kenneth G. Mann, Steven R. Steinhubl, and Alan D. Michelson. “Platelet function monitoring in patients with coronary artery disease.” J Am Coll Cardiol 50, no. 19 (November 6, 2007): 1822–34. https://doi.org/10.1016/j.jacc.2007.07.051.
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  - Storey, Robert F., Steen Husted, Robert A. Harrington, Stanley Heptinstall, Robert G. Wilcox, Gary Peters, Mark Wickens, et al. “Inhibition of platelet aggregation by AZD6140, a reversible oral P2Y12 receptor antagonist, compared with clopidogrel in patients with acute coronary syndromes.” J Am Coll Cardiol 50, no. 19 (November 6, 2007): 1852–56. https://doi.org/10.1016/j.jacc.2007.07.058.
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  - Gurbel, P. A., K. P. Bliden, I. Navickas, E. Cohen, and U. S. Tantry. “Post-coronary intervention recurrent ischemia in the presence of adequate platelet inhibition by dual antiplatelet therapy: what are we overlooking?” J Thromb Haemost 5, no. 11 (November 2007): 2300–2301. https://doi.org/10.1111/j.1538-7836.2007.02749.x.
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  - Gurbel, Paul A., Joseph DiChiara, and Udaya S. Tantry. “Antiplatelet therapy after implantation of drug-eluting stents: duration, resistance, alternatives, and management of surgical patients.” Am J Cardiol 100, no. 8B (October 22, 2007): 18M-25M. https://doi.org/10.1016/j.amjcard.2007.08.018.
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  - Dichiara, Joseph, Kevin P. Bliden, Udaya S. Tantry, Srivasavi K. Chaganti, Rolf P. Kreutz, Tania B. Gesheff, Yvonne Kreutz, and Paul A. Gurbel. “Platelet function measured by VerifyNow identifies generalized high platelet reactivity in aspirin treated patients.” Platelets 18, no. 6 (September 2007): 414–23. https://doi.org/10.1080/09537100701206824.
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  - Gurbel, Paul A., Kevin P. Bliden, Joseph DiChiara, Justin Newcomer, Willy Weng, Nagaraj K. Neerchal, Tania Gesheff, Srivasavi K. Chaganti, Amena Etherington, and Udaya S. Tantry. “Evaluation of dose-related effects of aspirin on platelet function: results from the Aspirin-Induced Platelet Effect (ASPECT) study.” Circulation 115, no. 25 (June 26, 2007): 3156–64. https://doi.org/10.1161/CIRCULATIONAHA.106.675587.
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  - Gurbel, P., K. P. Bliden, and U. Tantry. “Evidence that pre-existent variability in platelet response to ADP accounts for 'clopidogrel resistance': a rebuttal.” J Thromb Haemost 5, no. 5 (May 2007): 1087–88. https://doi.org/10.1111/j.1538-7836.2007.02509.x.
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  - Gurbel, Paul A., and Udaya S. Tantry. “[The role of clopidogrel in cardiovascular diseases].” Pol Arch Med Wewn 117, no. 5–6 (May 2007): 207–9.
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  - Bliden, Kevin P., Joseph DiChiara, Udaya S. Tantry, Ashwani K. Bassi, Srivasavi K. Chaganti, and Paul A. Gurbel. “Increased risk in patients with high platelet aggregation receiving chronic clopidogrel therapy undergoing percutaneous coronary intervention: is the current antiplatelet therapy adequate?” J Am Coll Cardiol 49, no. 6 (February 13, 2007): 657–66. https://doi.org/10.1016/j.jacc.2006.10.050.
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  - Tantry, Udaya S., Kevin P. Bliden, and Paul A. Gurbel. “AZD6140.” Expert Opin Investig Drugs 16, no. 2 (February 2007): 225–29. https://doi.org/10.1517/13543784.16.2.225.
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  - Gurbel, P. A., and D. E. Kandzari. “Stent thrombosis associated with first-generation drug-eluting stents: issues with antiplatelet therapy.” Neth Heart J 15, no. 4 (2007): 148–50. https://doi.org/10.1007/BF03085971.
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  - Gurbel, Paul A., Kevin P. Bliden, Amena Etherington, and Udaya S. Tantry. “Assessment of clopidogrel responsiveness: measurements of maximum platelet aggregation, final platelet aggregation and their correlation with vasodilator-stimulated phosphoprotein in resistant patients.” Thromb Res 121, no. 1 (2007): 107–15. https://doi.org/10.1016/j.thromres.2007.02.007.
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  - Gurbel, Paul A., Kevin P. Bliden, Kirk Guyer, Nikhil Aggarwal, and Udaya S. Tantry. “Delayed thrombin-induced platelet-fibrin clot generation by clopidogrel: a new dose-related effect demonstrated by thrombelastography in patients undergoing coronary artery stenting.” Thromb Res 119, no. 5 (2007): 563–70. https://doi.org/10.1016/j.thromres.2006.05.006.
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  - Gurbel, Paul A., and Udaya S. Tantry. “Stent thrombosis: role of compliance and nonresponsiveness to antiplatelet therapy.” Rev Cardiovasc Med 8 Suppl 1 (2007): S19–26.
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  - Gurbel, Paul A., and Udaya S. Tantry. “Clopidogrel resistance?” Thromb Res 120, no. 3 (2007): 311–21. https://doi.org/10.1016/j.thromres.2006.08.012.
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  - Kandzari, David E., Martin B. Leon, Jeffrey J. Popma, Peter J. Fitzgerald, Charles O’Shaughnessy, Michael W. Ball, Mark Turco, et al. “Comparison of zotarolimus-eluting and sirolimus-eluting stents in patients with native coronary artery disease: a randomized controlled trial.” J Am Coll Cardiol 48, no. 12 (December 19, 2006): 2440–47. https://doi.org/10.1016/j.jacc.2006.08.035.
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  - Gurbel, Paul A., Kevin P. Bliden, and Udaya S. Tantry. “Effect of clopidogrel with and without eptifibatide on tumor necrosis factor-alpha and C-reactive protein release after elective stenting: results from the CLEAR PLATELETS 1b study.” J Am Coll Cardiol 48, no. 11 (December 5, 2006): 2186–91. https://doi.org/10.1016/j.jacc.2005.12.084.
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  - Lau, Wei C., and Paul A. Gurbel. “Antiplatelet drug resistance and drug-drug interactions: Role of cytochrome P450 3A4.” Pharm Res 23, no. 12 (December 2006): 2691–2708. https://doi.org/10.1007/s11095-006-9084-4.
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  - Tantry, Udaya S., Kevin P. Bliden, and Paul A. Gurbel. “Prasugrel.” Expert Opin Investig Drugs 15, no. 12 (December 2006): 1627–33. https://doi.org/10.1517/13543784.15.12.1627.
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  - Gurbel, Paul A., and Udaya S. Tantry. “Aspirin and clopidogrel resistance: consideration and management.” J Interv Cardiol 19, no. 5 (October 2006): 439–48. https://doi.org/10.1111/j.1540-8183.2006.00181.x.
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  - Gurbel, Paul A., and Udaya S. Tantry. “Drug insight: Clopidogrel nonresponsiveness.” Nat Clin Pract Cardiovasc Med 3, no. 7 (July 2006): 387–95. https://doi.org/10.1038/ncpcardio0602.
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  - Tantry, U. S., K. P. Bliden, and P. A. Gurbel. “Reply.” Journal of the American College of Cardiology 47, no. 12 (June 20, 2006): 2566. https://doi.org/10.1016/j.jacc.2006.03.020.
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  - Tantry, Udaya S., Amena Etherington, Kevin P. Bliden, and Paul A. Gurbel. “Antiplatelet therapy: current strategies and future trends.” Future Cardiol 2, no. 3 (May 2006): 343–66. https://doi.org/10.2217/14796678.2.3.343.
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  - Bleske, Barry E., John M. Nicklas, Robert L. Bard, Robert D. Brook, Paul A. Gurbel, Kevin P. Bliden, Sanjay Rajagopalan, and Bertram Pitt. “Neutral effect on markers of heart failure, inflammation, endothelial activation and function, and vagal tone after high-dose HMG-CoA reductase inhibition in non-diabetic patients with non-ischemic cardiomyopathy and average low-density lipoprotein level.” J Am Coll Cardiol 47, no. 2 (January 17, 2006): 338–41. https://doi.org/10.1016/j.jacc.2005.06.087.
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  - Gurbel, P. A., and D. Singh. “Balloon angioplasty and repeat stenting may have similar long-term outcomes for people with in-stent restenosis: Commentary.” Evidence Based Cardiovascular Medicine 10, no. 1 (January 1, 2006): 47–48. https://doi.org/10.1016/j.ebcm.2006.01.007.
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  - Gurbel, Paul A. “The relationship of platelet reactivity to the occurrence of post-stenting ischemic events: emergence of a new cardiovascular risk factor.” Rev Cardiovasc Med 7 Suppl 4 (2006): S20–28.
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  - Gurbel, Paul A., Wei C. Lau, Kevin P. Bliden, and Udaya S. Tantry. “Clopidogrel resistance: implications for coronary stenting.” Curr Pharm Des 12, no. 10 (2006): 1261–69. https://doi.org/10.2174/138161206776361345.
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  - Wiviott, Stephen D., Udaya S. Tantry, Paul A. Gurbel, Paul A. American College of Cardiology, and Paul A. American Heart Association. “Clinical applications of antiplatelet therapy.” Rev Cardiovasc Med 7, no. 3 (2006): 130–46.
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  - Tantry, Udaya S., Kevin P. Bliden, and Paul A. Gurbel. “What is the best measure of thrombotic risks--pretreatment platelet aggregation, clopidogrel responsiveness, or posttreatment platelet aggregation?” Catheter Cardiovasc Interv 66, no. 4 (December 2005): 597–98. https://doi.org/10.1002/ccd.20526.
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  - Gurbel, Paul A., Kevin P. Bliden, Kirk Guyer, Peter W. Cho, Kazi A. Zaman, Rolf P. Kreutz, Ashwani K. Bassi, and Udaya S. Tantry. “Platelet reactivity in patients and recurrent events post-stenting: results of the PREPARE POST-STENTING Study.” J Am Coll Cardiol 46, no. 10 (November 15, 2005): 1820–26. https://doi.org/10.1016/j.jacc.2005.07.041.
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  - Gurbel, Paul A., Kevin P. Bliden, Waiel Samara, Jason A. Yoho, Kevin Hayes, Mulugeta Z. Fissha, and Udaya S. Tantry. “Clopidogrel effect on platelet reactivity in patients with stent thrombosis: results of the CREST Study.” J Am Coll Cardiol 46, no. 10 (November 15, 2005): 1827–32. https://doi.org/10.1016/j.jacc.2005.07.056.
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  - Tantry, Udaya S., Kevin P. Bliden, and Paul A. Gurbel. “Overestimation of platelet aspirin resistance detection by thrombelastograph platelet mapping and validation by conventional aggregometry using arachidonic acid stimulation.” J Am Coll Cardiol 46, no. 9 (November 1, 2005): 1705–9. https://doi.org/10.1016/j.jacc.2005.05.090.
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  - Tantry, Udaya S., Kevin P. Bliden, and Paul A. Gurbel. “Resistance to antiplatelet drugs: current status and future research.” Expert Opin Pharmacother 6, no. 12 (October 2005): 2027–45. https://doi.org/10.1517/14656566.6.12.2027.
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  - Kreutz, R. P., K. P. Bliden, U. S. Tantry, and P. A. Gurbel. “Viral respiratory tract infections increase platelet reactivity and activation: an explanation for the higher rates of myocardial infarction and stroke during viral illness.” J Thromb Haemost 3, no. 9 (September 2005): 2108–9. https://doi.org/10.1111/j.1538-7836.2005.01474.x.
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  - Michelson, A. D., M. Cattaneo, J. W. Eikelboom, P. Gurbel, K. Kottke-Marchant, T. J. Kunicki, F. M. Pulcinelli, et al. “Aspirin resistance: position paper of the Working Group on Aspirin Resistance.” J Thromb Haemost 3, no. 6 (June 2005): 1309–11. https://doi.org/10.1111/j.1538-7836.2005.01351.x.
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  - Gurbel, Paul A., Kevin P. Bliden, Kevin M. Hayes, Jason A. Yoho, William R. Herzog, and Udaya S. Tantry. “The relation of dosing to clopidogrel responsiveness and the incidence of high post-treatment platelet aggregation in patients undergoing coronary stenting.” J Am Coll Cardiol 45, no. 9 (May 3, 2005): 1392–96. https://doi.org/10.1016/j.jacc.2005.01.030.
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  - Hermiller, James B., Albert Raizner, Louis Cannon, Paul A. Gurbel, Michael A. Kutcher, S Chiu Wong, Mary E. Russell, et al. “Outcomes with the polymer-based paclitaxel-eluting TAXUS stent in patients with diabetes mellitus: the TAXUS-IV trial.” J Am Coll Cardiol 45, no. 8 (April 19, 2005): 1172–79. https://doi.org/10.1016/j.jacc.2004.10.075.
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  - Gurbel, Paul A., Kevin P. Bliden, Kazi A. Zaman, Jason A. Yoho, Kevin M. Hayes, and Udaya S. Tantry. “Clopidogrel loading with eptifibatide to arrest the reactivity of platelets: results of the Clopidogrel Loading With Eptifibatide to Arrest the Reactivity of Platelets (CLEAR PLATELETS) study.” Circulation 111, no. 9 (March 8, 2005): 1153–59. https://doi.org/10.1161/01.CIR.0000157138.02645.11.
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  - Kreutz, R. P., and P. A. Gurbel. “Subacute stent thrombosis in an elderly man with clopidogrel resistance.” Clinical Geriatrics 13, no. 3 (March 1, 2005): 37–40.
  - Poston, Robert, Junyan Gu, James Brown, James Gammie, Charles White, Jeffrey Manchio, Richard N. Pierson, et al. “Hypercoagulability affecting early vein graft patency does not exist after off-pump coronary artery bypass.” J Cardiothorac Vasc Anesth 19, no. 1 (February 2005): 11–18. https://doi.org/10.1053/j.jvca.2004.11.003.
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  - Gelzer-Bell, R., and P. A. Gurbel. “Diastolic heart failure in the older patient.” Clinical Geriatrics 13, no. 1 (January 1, 2005): 18–21.
  - Gurbel, Paul A., Kevin Hayes, Kevin P. Bliden, Jason Yoho, and Udaya S. Tantry. “The platelet-related effects of tenecteplase versus alteplase versus reteplase.” Blood Coagul Fibrinolysis 16, no. 1 (January 2005): 1–7. https://doi.org/10.1097/00001721-200501000-00001.
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  - Samara, Waiel M., Kevin P. Bliden, Udaya S. Tantry, and Paul A. Gurbel. “The difference between clopidogrel responsiveness and posttreatment platelet reactivity.” Thromb Res 115, no. 1–2 (2005): 89–94. https://doi.org/10.1016/j.thromres.2004.07.002.
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  - Gurbel, Paul A., Kevin P. Bliden, Kevin M. Hayes, and Udaya Tantry. “Platelet activation in myocardial ischemic syndromes.” Expert Rev Cardiovasc Ther 2, no. 4 (July 2004): 535–45. https://doi.org/10.1586/14779072.2.4.535.
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  - Joynt, Karen E., Wendy A. Gattis, Vic Hasselblad, Sergey Y. Fuzaylov, Victor L. Serebruany, Paul A. Gurbel, Laura H. Gaulden, G Michael Felker, David J. Whellan, and Christopher M. O’Connor. “Effect of angiotensin-converting enzyme inhibitors, beta blockers, statins, and aspirin on C-reactive protein levels in outpatients with heart failure.” Am J Cardiol 93, no. 6 (March 15, 2004): 783–85. https://doi.org/10.1016/j.amjcard.2003.12.010.
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  - Gurbel, Paul A., Waiel M. Samara, and Kevin P. Bliden. “Failure of clopidogrel to reduce platelet reactivity and activation following standard dosing in elective stenting: implications for thrombotic events and restenosis.” Platelets 15, no. 2 (March 2004): 95–99. https://doi.org/10.1080/09537100310001646950.
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  - Lau, Wei C., Paul A. Gurbel, Paul B. Watkins, Charlene J. Neer, Amy S. Hopp, David G. M. Carville, Kirk E. Guyer, Alan R. Tait, and Eric R. Bates. “Contribution of hepatic cytochrome P450 3A4 metabolic activity to the phenomenon of clopidogrel resistance.” Circulation 109, no. 2 (January 20, 2004): 166–71. https://doi.org/10.1161/01.CIR.0000112378.09325.F9.
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  - Gurbel, Paul A., and Kevin P. Bliden. “A new method of representing drug-induced platelet inhibition: better description of time course, response variability, non-response, and heightened activity.” Platelets 14, no. 7–8 (November 2003): 481–83. https://doi.org/10.1080/02697450310001632588.
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  - Gurbel, Paul A., and Kevin P. Bliden. “Platelet activation after stenting with heparin-coated versus noncoated stents.” Am Heart J 146, no. 4 (October 2003): E10. https://doi.org/10.1016/S0002-8703(03)00317-X.
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  - Serebruany, Victor L., Alex I. Malinin, Christopher M. O’connor, Paul A. Gurbel, and Paul A. Roxifiban Oral Compound Kinetics Evaluation Trial-I Platelet Substudy. “Effects of roxifiban on platelet aggregation and major receptor expression in patients with coronary artery disease for the Roxifiban Oral Compound Kinetics Evaluation Trial-I (ROCKET-I Platelet Substudy).” Am Heart J 146, no. 1 (July 2003): 91–98. https://doi.org/10.1016/S0002-8703(03)00186-8.
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  - Gurbel, Paul A., Kevin P. Bliden, Bonnie L. Hiatt, and Christopher M. O’Connor. “Clopidogrel for coronary stenting: response variability, drug resistance, and the effect of pretreatment platelet reactivity.” Circulation 107, no. 23 (June 17, 2003): 2908–13. https://doi.org/10.1161/01.CIR.0000072771.11429.83.
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  - Gurbel, P. A., K. P. Bliden, and B. L. Hiatt. “The early antiplatelet effects of clopidogrel loading for coronary stenting and the long-term stability of inhibition.” J Thromb Haemost 1, no. 6 (June 2003): 1319–21. https://doi.org/10.1046/j.1538-7836.2003.00184.x.
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  - Gurbel, P. A., and K. P. Bliden. “Interpretation of platelet inhibition by clopidogrel and the effect of non-responders.” J Thromb Haemost 1, no. 6 (June 2003): 1318–19. https://doi.org/10.1046/j.1538-7836.2003.t01-3-00326.x.
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  - Gurbel, Paul A., and Kevin P. Bliden. “Durability of platelet inhibition by clopidogrel.” Am J Cardiol 91, no. 9 (May 1, 2003): 1123–25. https://doi.org/10.1016/s0002-9149(03)00163-2.
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  - Serebruany, Victor L., Alex I. Malinin, Kevin P. Callahan, Azan Binbrek, Frans Van De Werf, John H. Alexander, Christopher B. Granger, Paul A. Gurbel, and Paul A. Assessment of the Safety and Efficacy of a New Thrombolytic Agent platelet substudy. “Effect of tenecteplase versus alteplase on platelets during the first 3 hours of treatment for acute myocardial infarction: the Assessment of the Safety and Efficacy of a New Thrombolytic Agent (ASSENT-2) platelet substudy.” Am Heart J 145, no. 4 (April 2003): 636–42. https://doi.org/10.1067/mhj.2003.210.
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  - Gurbel, Paul A., Charles C. Cummings, Christopher R. Bell, Amanda B. Alford, Andrew F. Meister, Victor L. Serebruany, and Victor L. Plavix Reduction Of New Thrombus Occurrence (PRONTO) trial. “Onset and extent of platelet inhibition by clopidogrel loading in patients undergoing elective coronary stenting: the Plavix Reduction Of New Thrombus Occurrence (PRONTO) trial.” Am Heart J 145, no. 2 (February 2003): 239–47. https://doi.org/10.1067/mhj.2003.109.
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  - Samara, Waiel M., and Paul A. Gurbel. “The role of platelet receptors and adhesion molecules in coronary artery disease.” Coron Artery Dis 14, no. 1 (February 2003): 65–79. https://doi.org/10.1097/00019501-200302000-00008.
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  - Gurbel, Paul A., and Kevin P. Bliden. “The stratification of platelet reactivity and activation in patients with stable coronary artery disease on aspirin therapy.” Thromb Res 112, no. 1–2 (2003): 9–12. https://doi.org/10.1016/j.thromres.2003.09.029.
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  - Gurbel, Paul A., Brian Galbut, Kevin P. Bliden, Raymond D. Bahr, Matthew T. Roe, Victor L. Serebruany, W Brian Gibler, Robert H. Christenson, E Magnus Ohman, and E Magnus EARLY Platelet Substudy. “Effect of eptifibatide for acute coronary syndromes: rapid versus late administration--therapeutic yield on platelets (The EARLY Platelet Substudy).” J Thromb Thrombolysis 14, no. 3 (December 2002): 213–19. https://doi.org/10.1023/a:1025048726396.
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  - Gurbel, Paul A., Bruce Austin, Peter W. Cho, and Alejandro J. Sequeira. “Correction of a saphenous vein graft to coronary vein anastamosis by selective retrograde coil-induced occlusion to arterialize the native vein.” Catheter Cardiovasc Interv 57, no. 4 (December 2002): 541–44. https://doi.org/10.1002/ccd.10347.
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  - Faxon, David P., Raymond J. Gibbons, Nicolas A. F. Chronos, Paul A. Gurbel, Florence Sheehan, and Florence HALT-MI Investigators. “The effect of blockade of the CD11/CD18 integrin receptor on infarct size in patients with acute myocardial infarction treated with direct angioplasty: the results of the HALT-MI study.” J Am Coll Cardiol 40, no. 7 (October 2, 2002): 1199–1204. https://doi.org/10.1016/s0735-1097(02)02136-8.
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  - Gurbel, Paul A., Kevin P. Callahan, Alex I. Malinin, Victor L. Serebruany, and Jeremy Gillis. “Could stent design affect platelet activation? Results of the Platelet Activation in STenting (PAST) Study.” J Invasive Cardiol 14, no. 10 (October 2002): 584–89.
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  - Bahr, Raymond D., Paul A. Gurbel, Alex I. Malinin, Charlyn Wentz, Robert H. Christenson, Matthew T. Roe, W Brian Gibler, Michael M. Kitt, E Magnus Ohman, and Victor L. Serebruany. “Relation of platelet activation and myocardial ischemia biomarkers dependent on type of chest pain (abrupt onset versus intermittent) in patients with angina pectoris or non-Q-wave acute myocardial infarction.” Am J Cardiol 90, no. 3 (August 1, 2002): 310–12. https://doi.org/10.1016/s0002-9149(02)02470-0.
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  - Gurbel, Paul A., Alex I. Malinin, Kevin P. Callahan, Victor L. Serebruany, and Christopher M. O’Connor. “Effect of loading with clopidogrel at the time of coronary stenting on platelet aggregation and glycoprotein IIb/IIIa expression and platelet-leukocyte aggregate formation.” Am J Cardiol 90, no. 3 (August 1, 2002): 312–15. https://doi.org/10.1016/s0002-9149(02)02471-2.
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  - Serebruany, V., M. McKenzie, A. Meister, S. Fuzaylov, P. Gurbel, D. Atar, W. Gattis, and C. O’Connor. “Whole blood impedance aggregometry for the assessment of platelet function in patients with congestive heart failure (EPCOT Trial).” Eur J Heart Fail 4, no. 4 (August 2002): 461–67. https://doi.org/10.1016/s1388-9842(02)00026-0.
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  - Gurbel, Paul A., Wendy A. Gattis, Sergey F. Fuzaylov, Laura Gaulden, Vic Hasselblad, Victor L. Serebruany, and Christopher M. O’Connor. “Evaluation of platelets in heart failure: is platelet activity related to etiology, functional class, or clinical outcomes?” Am Heart J 143, no. 6 (June 2002): 1068–75. https://doi.org/10.1067/mhj.2002.121261.
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  - Gurbel, Paul A., and Victor L. Serebruany. “Adhesion molecules, platelet activation, and cardiovascular risk.” Am Heart J 143, no. 2 (February 2002): 196–98. https://doi.org/10.1067/mhj.2002.120304.
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  - Callahan, K. P., A. I. Malinin, P. A. Gurbel, J. H. Alexander, C. B. Granger, D. Atar, and V. L. Serebruany. “Platelets and thrombolysis: Cooperation or contrariety?” Heartdrug 1, no. 5 (December 1, 2001): 281–90. https://doi.org/10.1159/000048975.
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  - Serebruany, V. L., A. I. Malinin, K. P. Callahan, P. A. Gurbel, and S. R. Steinhubl. “Statins do not affect platelet inhibition with clopidogrel during coronary stenting.” Atherosclerosis 159, no. 1 (November 2001): 239–41. https://doi.org/10.1016/s0021-9150(01)00606-2.
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  - Serebruany, V. L., C. C. Cummings, A. I. Malinin, S. R. Steinhubl, and P. A. Gurbel. “Uniform platelet activation exists before coronary stent implantation despite aspirin therapy.” Am Heart J 142, no. 4 (October 2001): 611–16. https://doi.org/10.1067/mhj.2001.116478.
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  - Serebruany, V. L., C. M. O’Connor, and P. A. Gurbel. “Effect of selective serotonin reuptake inhibitors on platelets in patients with coronary artery disease.” Am J Cardiol 87, no. 12 (June 15, 2001): 1398–1400. https://doi.org/10.1016/s0002-9149(01)01562-4.
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  - Serebruany, V. L., P. A. Gurbel, and C. M. O’Connor. “Platelet inhibition by sertraline and N-desmethylsertraline: a possible missing link between depression, coronary events, and mortality benefits of selective serotonin reuptake inhibitors.” Pharmacol Res 43, no. 5 (May 2001): 453–62. https://doi.org/10.1006/phrs.2001.0817.
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  - Serebruany, V. L., A. I. Malinin, C. R. Bell, and P. A. Gurbel. “Heparin prevents xylum clot signature analyser to detect platelet inhibition with clopidogrel during coronary stenting [2].” Thrombosis Research 102, no. 1 (April 1, 2001): 95–97. https://doi.org/10.1016/S0049-3848(01)00214-6.
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  - Serebruany, V. L., D. J. Levine, G. V. Nair, A. F. Meister, and P. A. Gurbel. “Usefulness of combining necrosis and platelet markers in triaging patients presenting with chest pain to the emergency department.” J Thromb Thrombolysis 11, no. 2 (April 2001): 155–62. https://doi.org/10.1023/a:1011280801335.
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  - Gurbel, P. A., C. M. O’Connor, M. R. Dalesandro, and V. L. Serebruany. “Relation of soluble and platelet P-selectin to early outcome in patients with acute myocardial infarction after thrombolytic therapy.” Am J Cardiol 87, no. 6 (March 15, 2001): 774-A7. https://doi.org/10.1016/s0002-9149(00)01502-2.
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  - Serebruany, V. L., A. B. Alford, A. F. Meister, S. Y. Fuzaylov, W. A. Gattis, P. A. Gurbel, and C. M. O’Connor. “Clinical utility of the platelet function analyzer (PFA-100) for the assessment of the platelet status in patients with congestive heart failure (EPCOT trial).” Thromb Res 101, no. 6 (March 15, 2001): 427–33. https://doi.org/10.1016/s0049-3848(00)00431-x.
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  - Ishizuka, Y., T. Minokawa, and S. Amemiya. “Micromere descendants at the blastula stage are involved in normal archenteron formation in sea urchin embryos.” Dev Genes Evol 211, no. 2 (February 2001): 83–88. https://doi.org/10.1007/s004270000120.
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  - Cummings, C. C., M. E. McKenzie, E. D. Horowitz, B. R. Oshrine, K. P. Callahan, P. A. Gurbel, and V. L. Serebruany. “Platelet function and total length of intracoronary stents: is there a correlation?” Thromb Res 101, no. 2 (January 15, 2001): 105–7. https://doi.org/10.1016/s0049-3848(00)00372-8.
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  - Callahan, K. P., A. I. Malinin, P. A. Gurbel, J. H. Alexander, C. B. Granger, and V. L. Serebruany. “Platelet function and fibrinolytic agents: two sides of a coin?” Cardiology 95, no. 2 (2001): 55–60. https://doi.org/10.1159/000047346.
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  - McKenzie, M. E., and P. A. Gurbel. “The potential of monoclonal antibodies to reduce reperfusion injury in myocardial infarction.” Biodrugs 15, no. 6 (2001): 395–404. https://doi.org/10.2165/00063030-200115060-00005.
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  - Gurbel, P. A., and V. L. Serebruany. “Oral platelet IIb/IIIa inhibitors: from attractive theory to clinical failures.” J Thromb Thrombolysis 10, no. 3 (December 2000): 217–20. https://doi.org/10.1023/a:1026582821645.
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  - O’connor, C. M., P. A. Gurbel, and V. L. Serebruany. “Depression and ischemic heart disease.” Am Heart J 140, no. 4 Suppl (October 2000): 63–69. https://doi.org/10.1067/mhj.2000.109979.
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  - Semaan, H. B., P. A. Gurbel, J. L. Anderson, J. B. Muhlestein, J. F. Carlquist, B. D. Horne, and V. L. Serebruany. “The effect of chronic azithromycin therapy on soluble endothelium-derived adhesion molecules in patients with coronary artery disease.” J Cardiovasc Pharmacol 36, no. 4 (October 2000): 533–37. https://doi.org/10.1097/00005344-200010000-00018.
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  - Serebruany, V. L., D. Atar, S. R. Murugesan, S. Jerome, H. Semaan, and P. A. Gurbel. “Effect of coronary thrombolysis on the plasma concentration of osteonectin (SPARC, BM40) in patients with acute myocardial infarction.” J Thromb Thrombolysis 10, no. 2 (October 2000): 197–202. https://doi.org/10.1023/a:1018774812613.
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  - Pothula, A., V. L. Serebruany, P. A. Gurbel, M. E. McKenzie, and D. Atar. “Pathophysiology and therapeutic modification of thrombin generation in patients with coronary artery disease.” Eur J Pharmacol 402, no. 1–2 (August 18, 2000): 1–10. https://doi.org/10.1016/s0014-2999(00)00440-4.
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  - Davis, C. J., P. A. Gurbel, W. A. Gattis, S. Y. Fuzaylov, G. V. Nair, C. M. O’Connor, and V. L. Serebruany. “Hemostatic abnormalities in patients with congestive heart failure: diagnostic significance and clinical challenge.” Int J Cardiol 75, no. 1 (August 2000): 15–21. https://doi.org/10.1016/s0167-5273(00)00300-4.
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  - Gurbel, P. A., D. J. Kereiakes, and V. L. Serebruany. “Soluble P-selectin is not a surrogate marker for platelet P-selectin: evidence from a multicenter chest pain study group.” J Thromb Thrombolysis 10, no. 1 (August 2000): 15–22. https://doi.org/10.1023/a:1018738502654.
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  - Gurbel, P. A., M. E. McKenzie, and V. L. Serebruany. “Initial platelet activity may predict efficacy after chronic oral glycoprotein IIb/IIIa blockade: should we still consider uniform treatment regimens?” Thromb Res 99, no. 1 (July 1, 2000): 105–7. https://doi.org/10.1016/s0049-3848(00)00229-2.
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  - Serebruany, V. L., D. R. Lowry, S. Y. Fuzailov, D. J. Levine, C. M. O’Connor, and P. A. Gurbel. “Moderate alcohol consumption is associated with decreased platelet activity in patients presenting with acute myocardial infarction.” J Thromb Thrombolysis 9, no. 3 (April 2000): 229–34. https://doi.org/10.1023/a:1018762510842.
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  - Gurbel, P. A., D. J. Kereiakes, M. R. Dalesandro, R. D. Bahr, C. M. O’Connor, and V. L. Serebruany. “Role of soluble and platelet-bound P-selectin in discriminating cardiac from noncardiac chest pain at presentation in the emergency department.” Am Heart J 139, no. 2 Pt 1 (February 2000): 320–28. https://doi.org/10.1067/mhj.2000.101109.
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  - Serebruany, V. L., M. E. McKenzie, D. J. Levin, and P. A. Gurbel. “Monitoring platelet inhibition during chronic oral platelet glycoprotein IIb/IIIa blockade: are we missing something?” Thromb Haemost 83, no. 2 (February 2000): 356–57.
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  - Gurbel, P. A., D. J. Kereiakes, D. Atar, and V. L. Serebruany. “Baseline platelet aggregation and major receptor expression predict subsequent activity following thrombolysis for acute myocardial infarction.” Scand Cardiovasc J 34, no. 1 (2000): 53–58. https://doi.org/10.1080/14017430050142404.
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  - Nair, G. V., P. A. Gurbel, S. Y. Fuzaylov, C. J. Davis, E. M. Ohman, R. D. Bahr, R. H. Christensen, and V. L. Serebruany. “Combining necrosis and platelet markers for perfecting myocardial infarction rule out: how close are we?” Cardiology 93, no. 1–2 (2000): 50–55. https://doi.org/10.1159/000007002.
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  - Semaan, H. B., P. A. Gurbel, J. L. Anderson, J. B. Muhlestein, J. F. Carlquist, B. D. Horne, and V. L. Serebruany. “Soluble VCAM-1 and E-selectin, but not ICAM-1 discriminate endothelial injury in patients with documented coronary artery disease.” Cardiology 93, no. 1–2 (2000): 7–10. https://doi.org/10.1159/000006995.
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  - Serebruany, V. L., D. J. Kereiakes, M. R. Dalesandro, and P. A. Gurbel. “The flow cytometer model markedly affects measurement of ex vivo whole blood platelet-bound P-selectin expression in patients with chest pain: are we comparing apples with oranges.” Thromb Res 96, no. 1 (October 1, 1999): 51–56. https://doi.org/10.1016/s0049-3848(99)00063-8.
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  - Serebruany, V. L., V. V. Yurovsky, and P. A. Gurbel. “Mild myocardial stunning affects platelet aggregation and certain hemostatic factors in swine.” Clin Appl Thromb Hemost 5, no. 4 (October 1999): 236–42. https://doi.org/10.1177/107602969900500406.
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  - Murugesan, S. R., P. A. Gurbel, and V. L. Serebruany. “Storing paraformaldehyde-fixed whole blood patient samples after chronic platelet glycoprotein IIb/IIIa blockade: core laboratory considerations.” Thromb Res 95, no. 4 (August 15, 1999): 201–3. https://doi.org/10.1016/s0049-3848(99)00048-1.
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  - Gurbel, P. A., C. M. O’Connor, C. C. Cummings, and V. L. Serebruany. “Clopidogrel: the future choice for preventing platelet activation during coronary stenting?” Pharmacol Res 40, no. 2 (August 1999): 107–11. https://doi.org/10.1006/phrs.1999.0478.
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  - Nair, G. V., P. A. Gurbel, C. M. O’Connor, W. A. Gattis, S. R. Murugesan, and V. L. Serebruany. “Depression, coronary events, platelet inhibition, and serotonin reuptake inhibitors.” Am J Cardiol 84, no. 3 (August 1, 1999): 321-A8. https://doi.org/10.1016/s0002-9149(99)00284-2.
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  - Serebruany, V. L., S. R. Murugesan, A. Pothula, D. Atar, D. R. Lowry, C. M. O’Connor, and P. A. Gurbel. “Increased soluble platelet/endothelial cellular adhesion molecule-1 and osteonectin levels in patients with severe congestive heart failure. Independence of disease etiology, and antecedent aspirin therapy.” Eur J Heart Fail 1, no. 3 (August 1999): 243–49. https://doi.org/10.1016/s1388-9842(99)00029-x.
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  - Gurbel, P. A., S. R. Murugesan, D. R. Lowry, and V. L. Serebruany. “Plasma thromboxane and prostacyclin are linear related and increased in patients presenting with acute myocardial infarction.” Prostaglandins Leukot Essent Fatty Acids 61, no. 1 (July 1999): 7–11. https://doi.org/10.1054/plef.1999.0064.
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  - O’Connor, C. M., P. A. Gurbel, and V. L. Serebruany. “Usefulness of soluble and surface-bound P-selectin in detecting heightened platelet activity in patients with congestive heart failure.” Am J Cardiol 83, no. 9 (May 1, 1999): 1345–49. https://doi.org/10.1016/s0002-9149(99)00098-3.
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  - Serebruany, V. L., and P. A. Gurbel. “The relations of major platelet receptor expression during myocardial infarction. Monitoring efficacy of GPIIb/IIIa inhibitors by measuring P-selectin?” Thromb Haemost 81, no. 2 (February 1999): 314–16.
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  - Serebruany, V. L., and P. A. Gurbel. “Assessment of platelet activity by measuring platelet-derived substances in plasma from patients with acute myocardial infarction: surprising lessons from the GUSTO-III Platelet Study.” Thromb Res 93, no. 3 (February 1, 1999): 149–50. https://doi.org/10.1016/s0049-3848(98)00176-5.
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  - McKenzie, M. E., A. Pothula, P. A. Gurbel, S. Y. Fuzaylov, C. M. O’Connor, W. A. Gattis, and V. L. Serebruany. “Failure of thrombin generation markers to triage patients presenting with chest pain.” Cardiology 92, no. 1 (1999): 53–58. https://doi.org/10.1159/000006946.
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  - McKenzie, M. E., P. A. Gurbel, D. J. Levine, and V. L. Serebruany. “Clinical utility of available methods for determining platelet function.” Cardiology 92, no. 4 (1999): 240–47. https://doi.org/10.1159/000006981.
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  - Serebruany, V. L., S. R. Murugesan, A. Pothula, H. Semaan, and P. A. Gurbel. “Soluble PECAM-1, but not P-selectin, nor osteonectin identify acute myocardial infarction in patients presenting with chest pain.” Cardiology 91, no. 1 (1999): 50–55. https://doi.org/10.1159/000006876.
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  - Serebruany, V. L., V. V. Yurovsky, and P. A. Gurbel. “Effects of a novel Mac-1 inhibitor, NPC 15669, on hemostatic parameters during preconditioned myocardial infarction.” Life Sci 65, no. 14 (1999): 1503–13. https://doi.org/10.1016/s0024-3205(99)00391-4.
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  - Serebruany, V. L., and P. A. Gurbel. “Effect of thrombolytic therapy on platelet expression and plasma concentration of PECAM-1 (CD31) in patients with acute myocardial infarction.” Arterioscler Thromb Vasc Biol 19, no. 1 (January 1999): 153–58. https://doi.org/10.1161/01.atv.19.1.153.
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  - Gurbel, P. A., V. Serebruany, W. J. Mergner, and F. Kolodgie. “Chapter 4 Myocardial cell injury during ischemia and reflow.” Principles of Medical Biology 13, no. C (December 1, 1998): 127–66. https://doi.org/10.1016/S1569-2582(98)80006-8.
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  - Gurbel, P. A., M. R. Dalesandro, and V. L. Serebruany. “Reteplase but not alteplase affects early soluble PECAM-1 and P-selectin release in patients with acute myocardial infarction.” Thromb Haemost 80, no. 4 (October 1998): 725.
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  - Serebruany, V. L., P. A. Gurbel, S. R. Murugesan, D. R. Lowry, E. Sturm, and S. I. Svetlov. “Depressed plasma platelet-activating factor acetylhydrolase in patients presenting with acute myocardial infarction.” Cardiology 90, no. 2 (October 1998): 127–30. https://doi.org/10.1159/000006831.
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  - Cheung, R. T. “Depressed platelet status in an elderly patient with hemorrhagic stroke after thrombolysis for acute myocardial infarction.” Stroke 29, no. 9 (September 1998): 2002–3. https://doi.org/10.1161/01.str.29.9.2002.
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  - Serebruany, V. L., M. L. Schlossberg, L. R. Edenbaum, W. R. Herzog, and P. A. Gurbel. “Serial changes of soluble endothelin-1 levels during myocardial ischaemia-reperfusion. Effects of magnesium, diltiazem and a novel MAC-1 inhibitor.” Pharmacol Res 38, no. 3 (September 1998): 165–72. https://doi.org/10.1006/phrs.1998.0349.
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  - Serebruany, V. L., P. A. Gurbel, A. R. Shustov, E. M. Ohman, and E. J. Topol. “Heterogeneity of platelet aggregation and major surface receptor expression in patients with acute myocardial infarction.” Am Heart J 136, no. 3 (September 1998): 398–405. https://doi.org/10.1016/s0002-8703(98)70212-1.
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  - Gurbel, P. A., V. L. Serebruany, A. R. Shustov, R. D. Bahr, C. Carpo, E. M. Ohman, and E. J. Topol. “Effects of reteplase and alteplase on platelet aggregation and major receptor expression during the first 24 hours of acute myocardial infarction treatment. GUSTO-III Investigators. Global Use of Strategies to Open Occluded Coronary Arteries.” J Am Coll Cardiol 31, no. 7 (June 1998): 1466–73. https://doi.org/10.1016/s0735-1097(98)00172-7.
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  - Serebruany, V. L., D. Atar, M. R. Dalesandro, C. M. O’Connor, and P. A. Gurbel. “Changes in hemostasis after parenteral magnesium in myocardial ischemia-reperfusion: from animal studies to clinical trials.” Magnes Res 11, no. 2 (June 1998): 133–40.
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  - Serebruany, V. L., S. R. Solomon, W. R. Herzog, and P. A. Gurbel. “Plasma fibronectin during myocardial ischemia-reperfusion: effects of magnesium, diltiazem, and a novel Mac-1 inhibitor.” Am J Hematol 57, no. 4 (April 1998): 309–14. https://doi.org/10.1002/(sici)1096-8652(199804)57:4<309::aid-ajh7>3.0.co;2-y.
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  - Gurbel, P. A., and V. L. Serebruany. “Soluble vascular cell adhesion molecule-1 and E-selectin in patients with acute myocardial infarction treated with thrombolytic agents.” Am J Cardiol 81, no. 6 (March 15, 1998): 772–75. https://doi.org/10.1016/s0002-9149(97)01035-7.
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  - Gurbel, P. A., V. L. Serebruany, A. R. Shustov, M. Dalesandro, C. I. Gumbs, L. B. Grablutz, R. D. Bahr, E. M. Ohman, and E. J. Topol. “Increased baseline levels of platelet P-selectin, and platelet-endothelial cell adhesion molecule-1 in patients with acute myocardial infarction as predictors of unsuccessful thrombolysis.” Coron Artery Dis 9, no. 7 (1998): 451–56. https://doi.org/10.1097/00019501-199809070-00008.
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  - Serebruany, V. L., J. V. Ordonez, V. V. Yurovsky, and P. A. Gurbel. “Crossreactivity of Human versus Swine Platelet Surface Antigens Is Similar for Glycoproteins Ib and IIIa, but Not for the Glycoprotein IIb/IIIa Complex.” J Thromb Thrombolysis 5, no. 1 (1998): 37–41. https://doi.org/10.1023/a:1008867930862.
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  - Serebruany, V. L., P. A. Gurbel, A. R. Shustov, M. R. Dalesandro, C. I. Gumbs, L. B. Grabletz, R. D. Bahr, E. M. Ohman, and E. J. Topol. “Depressed platelet status in an elderly patient with hemorrhagic stroke after thrombolysis for acute myocardial infarction. GUSTO-III Investigators.” Stroke 29, no. 1 (January 1998): 235–38. https://doi.org/10.1161/01.str.29.1.235.
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  - Serebruany, V. L., S. R. Solomon, A. R. Shustov, W. R. Herzog, and P. A. Gurbel. “Survival in Acute Myocardial Infarction Induced by Coronary Ligation: Prognostic Relevance of Certain Hemostatic Factors During the Occlusion Phase.” J Thromb Thrombolysis 5, no. 1 (1998): 29–35. https://doi.org/10.1023/A:1008815914024.
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  - Gurbel, P. A., and V. L. Serebruany. “Myths and realities of P-selectin plasma levels in patients with acute myocardial infarction.” Thromb Res 88, no. 3 (November 1, 1997): 343–44. https://doi.org/10.1016/s0049-3848(97)00263-6.
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  - Serebruany, V. L., M. L. Schlossberg, L. R. Edenbaum, W. R. Herzog, and P. A. Gurbel. “Effects of intracoronary diltiazem on certain hemostatic parameters during acute myocardial infarction in swine.” Int J Cardiol 61, no. 1 (August 29, 1997): 21–29. https://doi.org/10.1016/s0167-5273(97)00111-3.
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  - Serebruany, V. L., W. R. Herzog, M. L. Schlossberg, and P. A. Gurbel. “Bolus magnesium infusion in humans is associated with predominantly unfavourable changes in platelet aggregation and certain haemostatic factors.” Pharmacol Res 36, no. 1 (July 1997): 17–22. https://doi.org/10.1006/phrs.1997.0212.
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  - Gurbel, P. A., R. D. Anderson, H. O. Peels, A. J. van Boven, and P. den Heijer. “Coronary artery angioplasty with a helical autoperfusion balloon catheter.” Cathet Cardiovasc Diagn 40, no. 2 (February 1997): 179–85. https://doi.org/10.1002/(sici)1097-0304(199702)40:2<179::aid-ccd15>3.0.co;2-m.
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  - Serebruany, V. L., W. R. Herzog, and P. A. Gurbel. “Serial changes of the plasma prostanoids during myocardial ischemia-reperfusion in swine. Effects of magnesium, diltiazem, and a novel Mac-1 inhibitor.” Prostaglandins Leukot Essent Fatty Acids 56, no. 2 (February 1997): 135–42. https://doi.org/10.1016/s0952-3278(97)90510-x.
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  - Gurbel, P. A., F. J. Criado, E. A. Curnutte, P. Patten, and J. Secada-Lovio. “Percutaneous revascularization of an extensively diseased saphenous vein bypass graft with a saphenous vein-covered Palmaz stent.” Cathet Cardiovasc Diagn 40, no. 1 (January 1997): 75–78. https://doi.org/10.1002/(sici)1097-0304(199701)40:1<75::aid-ccd13>3.0.co;2-t.
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  - Serebruany, V. L., J. V. Ordonez, W. R. Herzog, M. Rohde, S. A. Mortensen, K. Folkers, and P. A. Gurbel. “Dietary coenzyme Q10 supplementation alters platelet size and inhibits human vitronectin (CD51/CD61) receptor expression.” J Cardiovasc Pharmacol 29, no. 1 (January 1997): 16–22. https://doi.org/10.1097/00005344-199701000-00003.
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  - Serebruany, V. L., P. A. Gurbel, J. V. Ordoñez, W. R. Herzog, M. Rohde, S. A. Mortensen, and K. Folkers. “Could coenzyme Q10 affect hemostasis by inhibiting platelet vitronectin (CD51/CD61) receptor?” Mol Aspects Med 18 Suppl (1997): S189–94. https://doi.org/10.1016/s0098-2997(97)00012-5.
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  - Serebruany, V. L., W. R. Herzog, M. L. Schlossberg, L. R. Edenbaum, and P. A. Gurbel. “Hemostatic changes after early versus late intracoronary magnesium during acute myocardial infarction in swine.” J Cardiovasc Pharmacol 28, no. 6 (December 1996): 817–23. https://doi.org/10.1097/00005344-199612000-00012.
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  - Serebruany, V. L., W. R. Herzog, and P. A. Gurbel. “Mild myocardial stunning affects platelet aggregation and hemostasis in swine.” Faseb Journal 10, no. 3 (December 1, 1996).
  - Serebruany, V. L., M. L. Schlossberg, L. R. Edenbaum, W. R. Herzog, and P. A. Gurbel. “Intracoronary magnesium and diltiazem affect to a similar extent certain hemostatic factors during acute myocardial infarction in swine.” Pharmacology 53, no. 4 (October 1996): 224–33. https://doi.org/10.1159/000139434.
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  - Serebruany, V. L., W. R. Herzog, L. R. Edenbaum, A. R. Shustov, and P. A. Gurbel. “Changes in the haemostatic profile during magnesium deficiency in swine.” Magnes Res 9, no. 3 (October 1996): 155–63.
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  - Serebruany, V. L., W. R. Herzog, and P. A. Gurbel. “Serial changes of natural antithrombotics during myocardial ischemia-reperfusion in swine. Effects of magnesium, diltiazem, and a novel Mac-1 inhibitor.” Blood Coagul Fibrinolysis 7, no. 6 (September 1996): 632–40. https://doi.org/10.1097/00001721-199609000-00009.
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  - Gurbel, P. A., V. L. Serebruany, S. F. Komiathy, M. E. Collins, G. D. Bittar, M. L. Schlossberg, and W. Mergner. “Pretreatment with an inhibitor of mac-1 alters regional and systemic platelet function during ischemia-reperfusion in swine.” Pharmacology 53, no. 2 (August 1996): 79–86. https://doi.org/10.1159/000139418.
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  - Serebruany, V. L., S. R. Solomon, L. R. Edenbaum, W. R. Herzog, and P. A. Gurbel. “Mac-1 inhibitor affects certain hemostatic parameters during myocardial stunning in swine.” Pharmacology 53, no. 2 (August 1996): 87–97. https://doi.org/10.1159/000139419.
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  - Serebruany, V. L., W. R. Herzog, S. P. Atamas, P. A. Gurbel, M. Rohde, S. A. Mortensen, and K. Folkers. “Hemostatic changes after dietary coenzyme Q10 supplementation in swine.” J Cardiovasc Pharmacol 28, no. 2 (August 1996): 175–81. https://doi.org/10.1097/00005344-199608000-00001.
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  - Anderson, R. D., and P. A. Gurbel. “The effect of intra-aortic balloon counterpulsation on coronary blood flow velocity distal to coronary artery stenoses.” Cardiology 87, no. 4 (July 1996): 306–12. https://doi.org/10.1159/000177111.
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  - Gurbel, P. A., F. I. Navetta, E. R. Bates, D. W. Muller, A. N. Tenaglia, M. J. Miller, B. Muhlstein, et al. “Lesion-directed administration of alteplase with intracoronary heparin in patients with unstable angina and coronary thrombus undergoing angioplasty.” Cathet Cardiovasc Diagn 37, no. 4 (April 1996): 382–91. https://doi.org/10.1002/(SICI)1097-0304(199604)37:4<382::AID-CCD8>3.0.CO;2-7.
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  - Gurbel, P. A. “"Functional characteristics of a new perfusion balloon: comparison with the Flowtrack 40 in a closed chest swine".” Cathet Cardiovasc Diagn 36, no. 4 (December 1995): 377–78. https://doi.org/10.1002/ccd.1810360425.
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  - Mörike, K., and G. Mikus. “Zofenopril after anterior myocardial infarction.” N Engl J Med 332, no. 25 (June 22, 1995): 1715.
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  - Benitez, R. M., P. A. Gurbel, H. Chong, and M. C. Rajasingh. “Penetrating atherosclerotic ulcer of the aortic arch resulting in extensive and fatal dissection.” Am Heart J 129, no. 4 (April 1995): 821–23. https://doi.org/10.1016/0002-8703(95)90335-6.
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  - Pimentel, C. X., S. W. Schreiter, and P. A. Gurbel. “The use of the Tracker catheter as a guidewire support device in angioplasty of angulated and tortuous circumflex coronary arteries.” J Invasive Cardiol 7, no. 3 (April 1995): 66–71.
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  - Gurbel, P. A., V. L. Serebruany, S. F. Komjathy, M. E. Collins, D. C. Sane, H. I. Scott, M. L. Schlossberg, and W. R. Herzog. “Regional and Systemic Platelet Function Is Altered by Myocardial Ischemia-Reperfusion.” J Thromb Thrombolysis 1, no. 2 (1995): 187–94. https://doi.org/10.1007/BF01062577.
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  - Herzog, W. R., P. A. Gurbel, R. A. Vogel, M. L. Schlossberg, A. I. Schneider, and V. L. Serebruany. “Effects of a Novel Leumedin NPC 15669 on Myocardial Stunning and Preconditioned Infarction Size in Swine.” J Thromb Thrombolysis 1, no. 2 (1995): 163–70. https://doi.org/10.1007/BF01062574.
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  - Serebruany, V. L., W. R. Herzog, P. A. Gurbel, M. L. Schlossberg, H. J. Scott, and R. A. Vogel. “NPC 15669, an Antiinflammatory Leucine Derivative, Reduces In Vitro Platelet Aggregability in Both Swine and Human Plasma.” J Thromb Thrombolysis 1, no. 2 (1995): 171–78. https://doi.org/10.1007/BF01062575.
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  - Gurbel, P. A., R. D. Anderson, C. S. MacCord, H. Scott, V. Serebruany, and W. R. Herzog. “Accelerated intravenous dosing of recombinant tissue-type plasminogen activator causes rapid but unstable reperfusion in a canine model of acute myocardial infarction.” Coron Artery Dis 5, no. 11 (November 1994): 929–36.
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  - Tapson, V. F., P. A. Gurbel, L. A. Witty, K. S. Pieper, and R. S. Stack. “Pharmacomechanical thrombolysis of experimental pulmonary emboli. Rapid low-dose intraembolic therapy.” Chest 106, no. 5 (November 1994): 1558–62. https://doi.org/10.1378/chest.106.5.1558.
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  - Ohman, E. M., B. S. George, C. J. White, M. J. Kern, P. A. Gurbel, R. J. Freedman, C. Lundergan, J. R. Hartmann, J. D. Talley, and M. J. Frey. “Use of aortic counterpulsation to improve sustained coronary artery patency during acute myocardial infarction. Results of a randomized trial. The Randomized IABP Study Group.” Circulation 90, no. 2 (August 1994): 792–99. https://doi.org/10.1161/01.cir.90.2.792.
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  - Ohman, E. M., J. F. Marquis, D. R. Ricci, R. I. Brown, M. L. Knudtson, D. J. Kereiakes, J. K. Samaha, J. R. Margolis, A. L. Niederman, and L. S. Dean. “A randomized comparison of the effects of gradual prolonged versus standard primary balloon inflation on early and late outcome. Results of a multicenter clinical trial. Perfusion Balloon Catheter Study Group.” Circulation 89, no. 3 (March 1994): 1118–25. https://doi.org/10.1161/01.cir.89.3.1118.
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  - Gurbel, P. A., C. S. MacCord, R. D. Anderson, H. Scott, D. Atar, W. Mergner, and W. R. Herzog. “A canine model of acute coronary artery thrombosis for the evaluation of reperfusion strategies.” Cardiology 84, no. 1 (1994): 1–8. https://doi.org/10.1159/000176322.
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  - Gurbel, P. A., R. D. Anderson, C. S. MacCord, H. Scott, S. F. Komjathy, J. Poulton, J. L. Stafford, and J. Godard. “Arterial diastolic pressure augmentation by intra-aortic balloon counterpulsation enhances the onset of coronary artery reperfusion by thrombolytic therapy.” Circulation 89, no. 1 (January 1994): 361–65. https://doi.org/10.1161/01.cir.89.1.361.
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  - Herzog, W. R., D. Atar, P. A. Gurbel, R. A. Vogel, M. L. Schlossberg, and V. L. Serebruany. “Effect of magnesium sulphate infusion on ex vivo platelet aggregation in swine.” Magnes Res 6, no. 4 (December 1993): 349–53.
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  - Tapson, V. F., C. J. Davidson, P. A. Gurbel, K. H. Sheikh, K. B. Kisslo, and R. S. Stack. “Rapid and accurate diagnosis of pulmonary emboli in a canine model using intravascular ultrasound imaging.” Chest 100, no. 5 (November 1991): 1410–13. https://doi.org/10.1378/chest.100.5.1410.
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  - Gurbel, P. A., C. J. Davidson, E. M. Ohman, J. E. Smith, and R. S. Stack. “Selective infusion of thrombolytic therapy in the acute myocardial infarct-related coronary artery as an alternative to rescue percutaneous transluminal coronary angioplasty.” Am J Cardiol 66, no. 12 (October 15, 1990): 1021–23. https://doi.org/10.1016/0002-9149(90)90945-w.
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  - Hurwitz, J. L., R. J. Kanter, P. Gurbel, R. A. Greenfield, J. H. Kasell, and C. J. Davidson. “AV blockade via selective AV nodal artery injection in a patient.” Am Heart J 120, no. 4 (October 1990): 986–88. https://doi.org/10.1016/0002-8703(90)90223-k.
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  - Navetta, F. I., M. J. Barber, P. A. Gurbel, R. W. Moreadith, R. Bernstein, M. A. Hlatky, R. E. Coleman, and T. M. Bashore. “Myocardial ischemia in constrictive pericarditis.” Am Heart J 116, no. 4 (October 1988): 1107–11. https://doi.org/10.1016/0002-8703(88)90171-8.
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  - Haber, R. H., E. Z. Oddone, P. A. Gurbel, and W. W. Stead. “Acute pulmonary decompensation due to amphotericin B in the absence of granulocyte transfusions.” N Engl J Med 315, no. 13 (September 25, 1986): 836. https://doi.org/10.1056/NEJM198609253151319.
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- Book Sections
  - Gurbel, P. A., Y. H. Jeong, and U. S. Tantry. “Phosphodiesterase inhibitors.” In Platelets, 979–89, 2019. https://doi.org/10.1016/B978-0-12-813456-6.00054-0.
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  - Tantry, U. S., A. Myat, and P. A. Gurbel. “Monitoring of antiplatelet therapy.” In Platelets in Thrombotic and Non-Thrombotic Disorders: Pathophysiology, Pharmacology and Therapeutics: An Update, 671–79, 2017. https://doi.org/10.1007/978-3-319-47462-5_45.
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  - Tantry, U. S., and P. A. Gurbel. “Markers of platelet function.” In New Therapeutic Agents in Thrombosis and Thrombolysis: Third Edition, 409–27, 2016.
  - Gurbel, P. A., M. Gesheff, K. P. Bliden, and U. S. Tantry. “Light Transmission Aggregometry.” In Antiplatelet Therapy in Cardiovascular Disease, 51–57, 2014. https://doi.org/10.1002/9781118493984.ch7.
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  - Gurbel, P. A., Y. H. Jeong, and U. S. Tantry. “Personalizing Antiplatelet Therapy.” In Antiplatelet Therapy in Cardiovascular Disease, 267–76, 2014. https://doi.org/10.1002/9781118493984.ch32.
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  - Gurbel, P. A., and U. S. Tantry. “Platelet Pathophysiology and its Role in Thrombosis.” In Antiplatelet Therapy in Cardiovascular Disease, 1–7, 2014. https://doi.org/10.1002/9781118493984.ch1.
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  - Tantry, U. S., K. P. Bliden, T. Meeran, and P. A. Gurbel. “Clopidogrel Resistance.” In Antiplatelet Therapy in Cardiovascular Disease, 285–92, 2014. https://doi.org/10.1002/9781118493984.ch34.
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  - Tantry, U. S., V. A. Doraiswamy, G. Stokken, M. J. Slepian, and P. A. Gurbel. “Thrombelastography and Other Novel Techniques.” In Antiplatelet Therapy in Cardiovascular Disease, 102–7, 2014. https://doi.org/10.1002/9781118493984.ch12.
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  - Gurbel, P. A., and U. S. Tantry. “Acute coronary syndromes.” In New Oral Anticoagulants, 35–57, 2013. https://doi.org/10.2217/EBO.12.69.
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  - Gurbel, P. A., and U. S. Tantry. “Monitoring of Antiplatelet Therapy.” In Platelets, 603–33, 2013. https://doi.org/10.1016/B978-0-12-387837-3.00030-4.
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  - Gurbel, P. A., and U. S. Tantry. “Antiplatelet drug resistance and variability in response: The role of antiplatelet therapy monitoring.” In Antiplatelet and Anticoagulation Therapy, 45–112, 2013. https://doi.org/10.1007/978-1-4471-4297-3_2.
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  - Gurbel, P. A., and U. S. Tantry. “Antithrombotic therapies.” In Advances in Acute Coronary Syndrome Management, 45–66, 2012. https://doi.org/10.2217/EBO.11.297.
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  - Gurbel, P. A., J. DiChiara, M. J. Antonino, and U. S. Tantry. “CRP and its role in coronary heart disease: New research developments.” In C-Reactive Protein: New Research, 35–42, 2009.
  - Tantry, U. S., T. A. Suarez, and P. A. Gurbel. “Thienopyridine Response Variability and Resistance.” In Antiplatelet Therapy In Ischemic Heart Disease, 77–93, 2009. https://doi.org/10.1002/9781444303339.ch6.
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  - Reichman, J. “Preface.” In Profili Evolutivi Del Diritto Industriale, Vol. 2001, 2001.
- Conference Papers
  - Mahla, Elisabeth, Florian Prueller, Sylvia Farzi, Gudrun Pregartner, Reinhard B. Raggam, Elisabeth Beran, Wolfgang Toller, Andrea Berghold, Udaya S. Tantry, and Paul A. Gurbel. “Does Platelet Reactivity Predict Bleeding in Patients Needing Urgent Coronary Artery Bypass Grafting During Dual Antiplatelet Therapy?” In Ann Thorac Surg, 102:2010–17, 2016. https://doi.org/10.1016/j.athoracsur.2016.05.003.
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  - Cornel, Jan H., E Magnus Ohman, Benjamin Neely, Peter Clemmensen, Piyamitr Sritara, Dmitry Zamoryakhin, Paul W. Armstrong, et al. “Impact of smoking status on platelet function and clinical outcomes with prasugrel vs. clopidogrel in patients with acute coronary syndromes managed without revascularization: Insights from the TRILOGY ACS trial.” In Am Heart J, 168:76-87.e1, 2014. https://doi.org/10.1016/j.ahj.2014.04.011.
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  - Alexander, W., C. M. Gibson, E. M. Hylek, and P. Gurbel. “American Heart Association 2008 Scientific Sessions. The ATLAS TIMI 46 trial: Rivaroxaban.” In P and T, 34:31, 2009.
  - Gurbel, P. A., and R. D. Anderson. “New concept in coronary angioplasty: dilatation with a helical balloon that allows simultaneous autoperfusion.” In Cathet Cardiovasc Diagn, 40:109–16, 1997. https://doi.org/10.1002/(sici)1097-0304(199701)40:1<109::aid-ccd21>3.0.co;2-m.
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