Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • M.D., University of Maryland - Baltimore 1983
• 

  Duke Appointment History

  • Associate, Medicine, Clinical Science Departments 1988 - 1989
• Publications & Artistic Works
• 

  Selected Publications

  • Books

    • Waksman, R, Gurbel, PA, and Gaglia, MA. Antiplatelet Therapy in Cardiovascular Disease. June 3, 2014.  Full Text

  • Academic Articles

    • Huo, Y, Jeong, YH, Gong, Y, Wang, D, He, B, Chen, J, Fu, G, Chen, Y, Li, J, Li, Y, Goto, S, Tantry, US, Gurbel, PA, Ahn, JH, Kim, HS, Ho Jeong, M, Han, Y, Smith, SC, and Ge, J. "2018 update of expert consensus statement on antiplatelet therapy in East Asian patients with ACS or undergoing PCI." Science Bulletin 64, no. 3 (February 15, 2019): 166-179.  Full Text
    • Bliden, KP, Raviv, G, Tantry, US, Chaudhary, R, Cochran, JW, Navarese, EP, Brannan, T, Vyas, A, and Gurbel, PA. ""Blueprinting" thrombogenicity and antithrombotic drug response at the bedside in patients presenting emergently with symptoms of acute stroke." Journal of Thrombosis and Thrombolysis 47, no. 2 (February 2019): 192-199.  Full Text
    • Koh, J-S, Park, Y, Ahn, J-H, Kang, MG, Kim, K-H, Bae, JS, Park, HW, Jang, JY, Park, JR, Hwang, S-J, Kwak, CH, Hwang, J-Y, Tantry, US, Gurbel, PA, and Jeong, Y-H. "Influence of Amlodipine on Haemostatic Measurements during Clopidogrel Treatment in Patients with Coronary Artery Disease." Thrombosis and Haemostasis 119, no. 2 (February 2019): 264-273.  Full Text
    • Åstrand, M, Amilon, C, Röshammar, D, Himmelmann, A, Angiolillo, DJ, Storey, RF, Gurbel, PA, Bonaca, MP, and Hamrén, B. "Pharmacokinetic-pharmacodynamic modelling of platelet response to ticagrelor in stable coronary artery disease and prior myocardial infarction patients." British Journal of Clinical Pharmacology 85, no. 2 (February 2019): 413-421.  Full Text
    • Gurbel, P, Tantry, U, and Weisman, S. "A narrative review of the cardiovascular risks associated with concomitant aspirin and NSAID use." Journal of Thrombosis and Thrombolysis 47, no. 1 (January 2019): 16-30. (Review)  Full Text
    • Tantry, US, Navarese, EP, Bliden, KP, and Gurbel, PA. "The potential of genotype-guided antiplatelet therapy: promises and challenges." Expert Review of Precision Medicine and Drug Development 3, no. 6 (November 2, 2018): 371-377.  Full Text
    • Gurbel, PA, Shah, P, Desai, S, and Tantry, US. "Antithrombotic Strategies and Device Thrombosis." Cardiology Clinics 36, no. 4 (November 2018): 541-550. (Review)  Full Text
    • Mahla, E, Tantry, US, Prüller, F, and Gurbel, PA. "Is There a Role for Preoperative Platelet Function Testing in Patients Undergoing Cardiac Surgery During Antiplatelet Therapy?." Circulation 138, no. 19 (November 2018): 2145-2159.  Full Text
    • Brener, SJ, Kirtane, AJ, Rinaldi, MJ, Stuckey, TD, Witzenbichler, B, Weisz, G, Neumann, F-J, Metzger, DC, Henry, TD, Cox, DA, Duffy, PL, Mazzaferri, EL, Gurbel, PA, Brodie, BR, Mehran, R, McAndrew, T, and Stone, GW. "Prediction of Ischemic and Bleeding Events Using the Dual Antiplatelet Therapy Score in an Unrestricted Percutaneous Coronary Intervention Population." Circ Cardiovasc Interv 11, no. 10 (October 2018): e006853-null.  Full Text  Link to Item
    • Hinohara, TT, Roe, MT, White, HD, Fox, KAA, Bhatt, DL, Hamm, C, Gurbel, PA, Aylward, PE, Wiviott, SD, Huber, K, Neely, ML, and Ohman, EM. "Outcomes of Patients Receiving Downstream Revascularization After Initial Medical Management for Non-ST-Segment Elevation Acute Coronary Syndromes (From the TRILOGY ACS Trial)." The American Journal of Cardiology 122, no. 8 (October 2018): 1322-1329.  Full Text
    • Navarese, EP, Wernly, B, Lichtenauer, M, Petrescu, AM, Kołodziejczak, M, Lauten, A, Frediani, L, Veulemanns, V, Wanha, W, Wojakowski, W, Lesiak, M, Ferrante, G, Zeus, T, Tantry, U, Bliden, K, Buffon, A, Contegiacomo, G, Jung, C, Kubica, J, Pestrichella, V, and Gurbel, PA. "Dual vs single antiplatelet therapy in patients with lower extremity peripheral artery disease - A meta-analysis." International Journal of Cardiology 269 (October 2018): 292-297.  Full Text
    • Tantry, U, Chaudhary, R, Kubica, J, Bliden, K, and Gurbel, PA. "Cangrelor for the treatment of patients with Arterial Thrombosis." Expert Opinion on Pharmacotherapy 19, no. 12 (August 13, 2018): 1389-1398. (Review)  Full Text
    • Giustino, G, Redfors, B, Kirtane, AJ, Mehran, R, Dangas, GD, Witzenbichler, B, Neumann, FJ, Weisz, G, Généreux, P, Maehara, A, McAndrew, T, Farhan, S, Rinaldi, MJ, Metzger, DC, Henry, TD, Cox, DA, Duffy, PL, Mazzaferri, EL, Brodie, BR, Stuckey, TD, Gurbel, P, Ben-Yehuda, O, and Stone, GW. "Platelet Reactivity and Risk of Ischemic Stroke After Coronary Drug-Eluting Stent Implantation: From the ADAPT-DES Study." Jacc: Cardiovascular Interventions 11, no. 13 (July 9, 2018): 1277-1286.  Full Text
    • Venkataraman, G, Bliden, KP, Tantry, US, and Gurbel, PA. "Thromboembolism after WATCHMAN^TM in a clopidogrel non-responder: A case for concern?." Catheterization and Cardiovascular Interventions 92, no. 1 (July 1, 2018): 200-202.  Full Text
    • Navarese, EP, Kołodziejczak, M, Petrescu, A, Wernly, B, Lichtenauer, M, Lauten, A, Buffon, A, Wanha, W, Pestrichella, V, Sardella, G, Contegiacomo, G, Tantry, U, Bliden, K, Kubica, J, and Gurbel, PA. "Role of proprotein convertase subtilisin/kexin type 9 inhibitors in patients with coronary artery disease undergoing percutaneous coronary intervention." Expert Review of Cardiovascular Therapy 16, no. 6 (June 2018): 419-429. (Review)  Full Text
    • Rana, R, Huang, T, Koukos, G, Fletcher, EK, Turner, SE, Shearer, A, Gurbel, PA, Rade, JJ, Kimmelstiel, CD, Bliden, KP, Covic, L, and Kuliopulos, A. "Noncanonical matrix metalloprotease 1-protease-Activated receptor 1 signaling drives progression of atherosclerosis." Arteriosclerosis, Thrombosis, and Vascular Biology 38, no. 6 (June 1, 2018): 1368-1380.  Full Text
    • Gurbel, PA, Tantry, US, D'Andrea, D, Chung, T, Alexander, JH, Bliden, KP, Wright, SD, and Tricoci, P. "Evaluation of potential antiplatelet effects of CSL112 (Apolipoprotein A-I [Human]) in patients with atherosclerosis: results from a phase 2a study." Journal of Thrombosis and Thrombolysis 45, no. 4 (May 2018): 469-476.  Full Text
    • Tantry, US, Navarese, EP, Myat, A, Chaudhary, R, and Gurbel, PA. "Combination oral antithrombotic therapy for the treatment of myocardial infarction: recent developments." Expert Opinion on Pharmacotherapy 19, no. 7 (May 2018): 653-665. (Review)  Full Text
    • Bergmeijer, TO, Reny, J-L, Pakyz, RE, Gong, L, Lewis, JP, Kim, E-Y, Aradi, D, Fernandez-Cadenas, I, Horenstein, RB, Lee, MTM, Whaley, RM, Montaner, J, Gensini, GF, Cleator, JH, Chang, K, Holmvang, L, Hochholzer, W, Roden, DM, Winter, S, Altman, RB, Alexopoulos, D, Kim, H-S, Déry, J-P, Gawaz, M, Bliden, K, Valgimigli, M, Marcucci, R, Campo, G, Schaeffeler, E, Dridi, NP, Wen, M-S, Shin, JG, Simon, T, Fontana, P, Giusti, B, Geisler, T, Kubo, M, Trenk, D, Siller-Matula, JM, Ten Berg, JM, Gurbel, PA, Hulot, J-S, Mitchell, BD, Schwab, M, Ritchie, MD, Klein, TE, Shuldiner, AR, and ICPC Investigators, . "Genome-wide and candidate gene approaches of clopidogrel efficacy using pharmacodynamic and clinical end points-Rationale and design of the International Clopidogrel Pharmacogenomics Consortium (ICPC)." American Heart Journal 198 (April 2018): 152-159. (Review)  Full Text
    • Navarese, EP, Robinson, JG, Kowalewski, M, Kolodziejczak, M, Andreotti, F, Bliden, K, Tantry, U, Kubica, J, Raggi, P, and Gurbel, PA. "Association Between Baseline LDL-C Level and Total and Cardiovascular Mortality After LDL-C Lowering: A Systematic Review and Meta-analysis." Jama 319, no. 15 (April 2018): 1566-1579. (Review)  Full Text
    • Tantry, US, Navarese, EP, Myat, A, and Gurbel, PA. "Selection of P2Y12 Inhibitor in Percutaneous Coronary Intervention and/or Acute Coronary Syndrome." Progress in Cardiovascular Diseases 60, no. 4-5 (January 12, 2018): 460-470. (Review)  Full Text
    • Bae, JS, Ahn, J-H, Tantry, US, Gurbel, PA, and Jeong, Y-H. "Should Antithrombotic Treatment Strategies in East Asians Differ from Caucasians?." Current Vascular Pharmacology 16, no. 5 (January 2018): 459-476.  Full Text
    • Navarese, EP, Wernly, B, Lichtenauer, M, Pepe, M, Wanha, W, Ferrante, G, Frediani, L, Veulemans, V, Zeus, T, Westenfeld, R, Jung, C, and Gurbel, PA. "Prime time for the sweet spot in timing of coronary invasive approach in patients with non-ST elevation myocardial infarction." Journal of Thoracic Disease 10, no. 1 (January 2018): 17-20.  Full Text
    • Tantry, US, Navarese, EP, Bliden, KP, and Gurbel, PA. "Acetylsalicylic acid and clopidogrel hyporesponsiveness following acute coronary syndromes." Kardiologia Polska 76, no. 9 (January 2018): 1312-1319. (Review)  Full Text
    • Angiolillo, DJ, Rollini, F, Storey, RF, Bhatt, DL, James, S, Schneider, DJ, Sibbing, D, So, DYF, Trenk, D, Alexopoulos, D, Gurbel, PA, Hochholzer, W, De Luca, L, Bonello, L, Aradi, D, Cuisset, T, Tantry, US, Wang, TY, Valgimigli, M, Waksman, R, Mehran, R, Montalescot, G, Franchi, F, and Price, MJ. "International Expert Consensus on Switching Platelet P2Y12 Receptor-Inhibiting Therapies." Circulation 136, no. 20 (November 2017): 1955-1975. (Review)  Full Text
    • Chaudhary, R, Mathew, D, Bliden, K, Tantry, US, Sharma, T, Gesheff, MG, Franzese, CJ, Pandya, S, Toth, PP, and Gurbel, PA. "Low-density lipoprotein 4: a novel predictor of coronary artery disease severity." Current Medical Research and Opinion 33, no. 11 (November 2017): 1979-1984.  Full Text
    • Shah, P, Tantry, US, Bliden, KP, and Gurbel, PA. "Bleeding and thrombosis associated with ventricular assist device therapy." The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation 36, no. 11 (November 2017): 1164-1173. (Review)  Full Text
    • Winter, M-P, Grove, EL, De Caterina, R, Gorog, DA, Ahrens, I, Geisler, T, Gurbel, PA, Tantry, U, Navarese, EP, and Siller-Matula, JM. "Advocating cardiovascular precision medicine with P2Y12 receptor inhibitors." European Heart Journal. Cardiovascular Pharmacotherapy 3, no. 4 (October 2017): 221-234. (Review)  Full Text
    • Gurbel, PA, Navarese, EP, and Tantry, US. "Exploration of PCSK9 as a Cardiovascular Risk Factor: Is There a Link to the Platelet?." Journal of the American College of Cardiology 70, no. 12 (September 19, 2017): 1463-1466.  Full Text
    • Stuckey, TD, Kirtane, AJ, Brodie, BR, Witzenbichler, B, Litherland, C, Weisz, G, Rinaldi, MJ, Neumann, F-J, Metzger, DC, Henry, TD, Cox, DA, Duffy, PL, Mazzaferri, EL, Gurbel, PA, Mehran, R, Généreux, P, Ben-Yehuda, O, Simonton, CA, Stone, GW, and ADAPT-DES Investigators, . "Impact of Aspirin and Clopidogrel Hyporesponsiveness in Patients Treated With Drug-Eluting Stents: 2-Year Results of a Prospective, Multicenter Registry Study." Jacc. Cardiovascular Interventions 10, no. 16 (August 2, 2017): 1607-1617.  Full Text
    • Chen, G, Bliden, KP, Chaudhary, R, Liu, F, Kaza, H, Navarese, EP, Tantry, US, and Gurbel, PA. "Central aortic pulse pressure, thrombogenicity and cardiovascular risk." Journal of Thrombosis and Thrombolysis 44, no. 2 (August 2017): 223-233.  Full Text
    • Tantry, US, Jeong, Y-H, and Gurbel, PA. "More Evidence for Non-P2Y12-Mediated Effects of Ticagrelor." Jacc. Cardiovascular Interventions 10, no. 16 (August 2017): 1659-1661.  Full Text
    • Kolodziejczak, M, Andreotti, F, Kowalewski, M, Buffon, A, Ciccone, MM, Parati, G, Scicchitano, P, Uminska, JM, De Servi, S, Bliden, KP, Kubica, J, Bortone, A, Crea, F, Gurbel, P, and Navarese, EP. "Implantable Cardioverter-Defibrillators for Primary Prevention in Patients With Ischemic or Nonischemic Cardiomyopathy: A Systematic Review and Meta-analysis." Annals of Internal Medicine 167, no. 2 (July 2017): 103-111. (Review)  Full Text
    • Gurbel, PA, Defilippi, CR, Bliden, KP, and Tantry, US. "HIV infection, ACS, PCI and high platelet reactivity: Ingredients for a perfect thrombotic storm." European Heart Journal 38, no. 21 (June 1, 2017): 1687-1689. (Review)  Full Text
    • Bliden, KP, Chaudhary, R, Mohammed, N, Muresan, AA, Lopez-Espina, CG, Cohen, E, Raviv, G, Doubleday, M, Zaman, F, Mathew, B, Tantry, US, and Gurbel, PA. "Determination of non-Vitamin K oral anticoagulant (NOAC) effects using a new-generation thrombelastography TEG 6s system." Journal of Thrombosis and Thrombolysis 43, no. 4 (May 2017): 437-445.  Full Text
    • Gurbel, PA, and Tantry, US. "GEMINI-ACS-1: toward unearthing the antithrombotic therapy cornerstone for acute coronary syndromes." Lancet (London, England) 389, no. 10081 (May 2017): 1773-1775.  Full Text
    • Park, Y, Tantry, US, Koh, J-S, Ahn, J-H, Kang, MG, Kim, KH, Jang, JY, Park, HW, Park, J-R, Hwang, S-J, Park, K-S, Kwak, CH, Hwang, J-Y, Gurbel, PA, and Jeong, Y-H. "Novel role of platelet reactivity in adverse left ventricular remodelling after ST-segment elevation myocardial infarction: The REMODELING Trial." Thrombosis and Haemostasis 117, no. 5 (May 2017): 911-922.  Full Text
    • Secemsky, EA, Yeh, RW, Kereiakes, DJ, Cutlip, DE, Cohen, DJ, Steg, PG, Cannon, CP, Apruzzese, PK, D'Agostino, RB, Massaro, JM, Mauri, L, Kaplan, A, Ahmed, A, Ahmed, AH, Albirini, A, Moreyra, A, Rabinowitz, A, Shroff, A, Moak, A, Jacobs, A, Kabour, A, Gupta, A, Irimpen, A, Rosenthal, A, Taussig, A, Ferraro, A, Chhabra, A, Pucillo, A, Spaedy, A, White, A, Pratsos, A, Shakir, A, Ghitis, A, Agarwal, A, Jain, A, Chawla, A, Tang, A, Barker, B, Bertolet, B, Uretsky, B, Erickson, B, Rama, B, McLaurin, B, Dearing, B, Negus, B, Price, B, Brott, B, Bhambi, B, Bowers, B, Watt, B, Donohue, B, Hassel, CD, Croft, C, Lambert, C, O'Shaughnessy, C, Shoultz, C, Kim, C, Caputo, C, Nielson, C, Scott, C, Wolfe, C, McKenzie, C, Brachfeld, C, Thieling, C, Fisher, D, Lee, D, Simon, D, Churchill, D, Dobies, D, Eich, D, Goldberg, D, Griffin, D, Henderson, D, Kandzari, D, Lewis, D, Mego, D, Paniagua, D, Rizik, D, and Roberts, D. "Mortality following cardiovascular and bleeding events occurring beyond 1 year after coronary stenting: A secondary analysis of the Dual Antiplatelet Therapy (DAPT) Study." Jama Cardiology 2, no. 5 (May 1, 2017): 478-487.  Full Text
    • Jakubowski, JA, Erlinge, D, Alexopoulos, D, Small, DS, Winters, KJ, Gurbel, PA, and Angiolillo, DJ. "The Rationale for and Clinical Pharmacology of Prasugrel 5 mg." American journal of cardiovascular drugs : drugs, devices, and other interventions 17, no. 2 (April 2017): 109-121. (Review)  Full Text
    • Patel, MR, Fowkes, FGR, and Hiatt, WR. "Ticagrelor versus Clopidogrel in Peripheral Artery Disease." The New England journal of medicine 376, no. 15 (April 2017): 1488-1489. (Letter)  Full Text
    • Gurbel, PA, Price, MJ, Dahlen, JR, and Tantry, US. "ANTARCTIC: platelet function testing to adjust therapy." The Lancet 389, no. 10075 (March 2017): 1193-1193.  Full Text
    • Koh, J-S, Park, Y, Tantry, US, Ahn, J-H, Kang, MG, Kim, K, Jang, JY, Park, HW, Park, JR, Hwang, S-J, Kwak, CH, Hwang, J-Y, Gurbel, PA, and Jeong, Y-H. "Pharmacodynamic effects of a new fixed-dose clopidogrel-aspirin combination compared with separate administration of clopidogrel and aspirin in patients treated with coronary stents: The ACCEL-COMBO trial." Platelets 28, no. 2 (March 2017): 187-193.  Full Text
    • Tantry, US, and Gurbel, PA. "Rapid Desensitization of the Patients With Aspirin Hypersensitivity and Coronary Artery Disease." Circulation. Cardiovascular Interventions 10, no. 2 (February 2017).  Full Text
    • Navarese, EP, Gurbel, PA, Andreotti, F, Kołodziejczak, MM, Palmer, SC, Dias, S, Buffon, A, Kubica, J, Kowalewski, M, Jadczyk, T, Laskiewicz, M, Jędrzejek, M, Brockmeyer, M, Airoldi, F, Ruospo, M, De Servi, S, Wojakowski, W, O' Connor, C, and Strippoli, GFM. "Prevention of contrast-induced acute kidney injury in patients undergoing cardiovascular procedures-a systematic review and network meta-analysis." Plos One 12, no. 2 (January 2017): e0168726-null. (Review)  Full Text
    • Sharma, T, Bliden, K, Chaudhary, R, Tantry, U, and Gurbel, PA. "Efficacy of aspirin (325 mg) + omeprazole (40 mg) in treating coronary artery disease." Expert opinion on pharmacotherapy 18, no. 1 (January 2017): 123-131. (Review)  Full Text
    • Gurbel, PA, Bliden, KP, Chaudhary, R, Patrick, J, Liu, F, Chen, G, McLeod, C, and Tantry, US. "Antiplatelet Effect Durability of a Novel, 24-Hour, Extended-Release Prescription Formulation of Acetylsalicylic Acid in Patients With Type 2 Diabetes Mellitus." The American journal of cardiology 118, no. 12 (December 2016): 1941-1947.  Full Text
    • Kim, JH, Shah, P, Tantry, US, and Gurbel, PA. "Coagulation Abnormalities in Heart Failure: Pathophysiology and Therapeutic Implications." Current heart failure reports 13, no. 6 (December 2016): 319-328. (Review)  Full Text
    • Myat, A, Tantry, US, Kubica, J, and Gurbel, PA. "Current controversies in the use of aspirin and ticagrelor for the treatment of thrombotic events." Expert Review of Cardiovascular Therapy 14, no. 12 (December 2016): 1361-1370. (Review)  Full Text
    • Cornel, JH, Ohman, EM, Neely, B, Jakubowski, JA, Bhatt, DL, White, HD, Ardissino, D, Fox, KAA, Prabhakaran, D, Armstrong, PW, Erlinge, D, Tantry, US, Gurbel, PA, and Roe, MT. "Relationship of Platelet Reactivity With Bleeding Outcomes During Long-Term Treatment With Dual Antiplatelet Therapy for Medically Managed Patients With Non-ST-Segment Elevation Acute Coronary Syndromes." Journal of the American Heart Association 5, no. 11 (November 4, 2016).  Full Text
    • Gurbel, PA, Bliden, KP, Baker, BA, Dahlen, J, and Tantry, US. "Cigarette Smoking, Clopidogrel Responsiveness, and Hemoglobin Level." Jacc. Cardiovascular Interventions 9, no. 22 (November 2016): 2364-null. (Letter)  Full Text
    • Gurbel, PA, Bliden, KP, Tantry, US, Monroe, AL, Muresan, AA, Brunner, NE, Lopez-Espina, CG, Delmenico, PR, Cohen, E, Raviv, G, Haugen, DL, and Ereth, MH. "First report of the point-of-care TEG: A technical validation study of the TEG-6S system." Platelets 27, no. 7 (November 2016): 642-649.  Full Text
    • Gurbel, PA, Jeong, Y-H, and Tantry, US. "The Dogged Search for Cryptic Effects of Ticagrelor: Wishful Thinking or Real Benefits Beyond P2Y12 Inhibition?." Circulation 134, no. 22 (November 2016): 1720-1723.  Full Text
    • Gurbel, PA, and Tantry, US. "Antiplatelet therapy: What have we learned from the ANTARCTIC trial?." Nature Reviews Cardiology 13, no. 11 (November 1, 2016): 639-640.  Full Text
    • Chaudhary, R, Saadin, K, Bliden, KP, Harris, WS, Dinh, B, Sharma, T, Tantry, US, and Gurbel, PA. "Risk factors associated with plasma omega-3 fatty acid levels in patients with suspected coronary artery disease." Prostaglandins, leukotrienes, and essential fatty acids 113 (October 2016): 40-45.  Full Text
    • Bliden, KP, Chaudhary, R, Lopez, LR, Damrongwatanasuk, R, Guyer, K, Gesheff, MG, Franzese, CJ, Kaza, H, Tantry, US, and Gurbel, PA. "Oxidized Low-Density Lipoprotein-β2-Glycoprotein I Complex But Not Free Oxidized LDL Is Associated With the Presence and Severity of Coronary Artery Disease." The American journal of cardiology 118, no. 5 (September 2016): 673-678.  Full Text
    • Chaudhary, R, Bliden, KP, Garg, J, Mohammed, N, Tantry, U, Mathew, D, Toth, PP, Franzese, C, Gesheff, M, Pandya, S, and Gurbel, P. "Statin therapy and inflammation in patients with diabetes treated with high dose aspirin." Journal of Diabetes and its Complications 30, no. 7 (September 2016): 1365-1370.  Full Text
    • Bliden, KP, Tantry, US, Chaudhary, R, Byun, S, and Gurbel, PA. "Extended-release acetylsalicylic acid for secondary prevention of stroke and cardiovascular events." Expert Review of Cardiovascular Therapy 14, no. 7 (July 2016): 779-791. (Review)  Full Text
    • Kubica, J, Kubica, A, Jilma, B, Adamski, P, Hobl, E-L, Navarese, EP, Siller-Matula, JM, Dąbrowska, A, Fabiszak, T, Koziński, M, and Gurbel, PA. "Impact of morphine on antiplatelet effects of oral P2Y12 receptor inhibitors." International Journal of Cardiology 215 (July 2016): 201-208. (Review)  Full Text
    • Bedeir, K, Bliden, K, Tantry, U, Gurbel, PA, and Mahla, E. "Timing of Coronary Bypass Surgery in Patients Receiving Clopidogrel: The Role of VerifyNow." The Canadian Journal of Cardiology 32, no. 6 (June 2016): 724-725.  Full Text
    • Giustino, G, Kirtane, AJ, Baber, U, Généreux, P, Witzenbichler, B, Neumann, F-J, Weisz, G, Maehara, A, Rinaldi, MJ, Metzger, C, Henry, TD, Cox, DA, Duffy, PL, Mazzaferri, EL, Brodie, BR, Stuckey, TD, Gurbel, PA, Dangas, GD, Francese, DP, Ozan, O, Mehran, R, and Stone, GW. "Impact of Anemia on Platelet Reactivity and Ischemic and Bleeding Risk: From the Assessment of Dual Antiplatelet Therapy With Drug-Eluting Stents Study." The American Journal of Cardiology 117, no. 12 (June 2016): 1877-1883.  Full Text
    • Gurbel, PA, and Tantry, US. "Antithrombotic therapy in medically managed patients with non-ST-segment elevation acute coronary syndromes." Heart (British Cardiac Society) 102, no. 11 (June 2016): 882-892. (Review)  Full Text
    • Kwon, TJ, Tantry, US, Park, Y, Choi, Y-M, Ahn, J-H, Kim, KH, Koh, J-S, Park, J-R, Hwang, S-J, Kwak, CH, Hwang, J-Y, Gurbel, PA, Smith, SC, and Jeong, Y-H. "Influence of platelet reactivity on BARC classification in East Asian patients undergoing percutaneous coronary intervention. Results of the ACCEL-BLEED study." Thrombosis and Haemostasis 115, no. 5 (May 2016): 979-992.  Full Text
    • Navarese, EP, Kolodziejczak, M, Kereiakes, DJ, Tantry, US, O'Connor, C, and Gurbel, PA. "Proprotein Convertase Subtilisin/Kexin Type 9 Monoclonal Antibodies for Acute Coronary Syndrome: A Narrative Review." Annals of Internal Medicine 164, no. 9 (May 2016): 600-607. (Review)  Full Text
    • Bliden, KP, Tantry, US, Gesheff, MG, Franzese, CJ, Pandya, S, Toth, PP, Mathew, DP, Chaudhary, R, and Gurbel, PA. "Thrombin-Induced Platelet-Fibrin Clot Strength Identified by Thrombelastography: A Novel Prothrombotic Marker of Coronary Artery Stent Restenosis." Journal of Interventional Cardiology 29, no. 2 (April 2016): 168-178.  Full Text
    • Chaudhary, R, Bliden, KP, Tantry, US, Mohammed, N, Mathew, D, Gesheff, MG, Franzese, CJ, and Gurbel, PA. "Association of weight gain with coronary artery disease, inflammation and thrombogenicity." Journal of thrombosis and thrombolysis 41, no. 3 (April 2016): 394-403.  Full Text
    • Gurbel, PA, Jeong, Y-H, Navarese, EP, and Tantry, US. "Platelet-Mediated Thrombosis: From Bench to Bedside." Circulation research 118, no. 9 (April 2016): 1380-1391. (Review)  Full Text
    • Gurbel, PA, and Tantry, US. "Deciding about prolonged ticagrelor therapy in coronary clot formers: an ongoing dilemma." European heart journal 37, no. 14 (April 2016): 1143-1144.  Full Text
    • Reny, J-L, Fontana, P, Hochholzer, W, Neumann, FJ, Ten Berg, J, Janssen, PW, Geisler, T, Gawaz, M, Marcucci, R, Gori, A-M, Cuisset, T, Alessi, M-C, Berdagué, P, Gurbel, PA, Yong, G, Angiolillo, DJ, Aradi, D, Beigel, R, Campo, G, and Combescure, C. "Vascular risk levels affect the predictive value of platelet reactivity for the occurrence of MACE in patients on clopidogrel. Systematic review and meta-analysis of individual patient data." Thrombosis and Haemostasis 115, no. 4 (April 2016): 844-855. (Review)  Full Text
    • Doll, JA, Neely, ML, Roe, MT, Armstrong, PW, White, HD, Prabhakaran, D, Winters, KJ, Duvvuru, S, Sundseth, SS, Jakubowski, JA, Gurbel, PA, Bhatt, DL, Ohman, EM, Fox, KAA, and TRILOGY ACS Investigators, . "Impact of CYP2C19 Metabolizer Status on Patients With ACS Treated With Prasugrel Versus Clopidogrel." Journal of the American College of Cardiology 67, no. 8 (March 2016): 936-947.  Full Text
    • King, KR, Grazette, LP, Paltoo, DN, McDevitt, JT, Sia, SK, Barrett, PM, Apple, FS, Gurbel, PA, Weissleder, R, Leeds, H, Iturriaga, EJ, Rao, AK, Adhikari, B, Desvigne-Nickens, P, Galis, ZS, and Libby, P. "Point-of-Care Technologies for Precision Cardiovascular Care and Clinical Research: National Heart, Lung, and Blood Institute Working Group." Jacc: Basic to Translational Science 1, no. 1-2 (February 1, 2016): 73-86. (Review)  Full Text
    • Bliden, KP, Patrick, J, Pennell, AT, Tantry, US, and Gurbel, PA. "Drug delivery and therapeutic impact of extended-release acetylsalicylic acid." Future cardiology 12, no. 1 (January 2016): 45-58. (Review)  Full Text
    • Gurbel, PA, Bliden, KP, Turner, SE, Tantry, US, Gesheff, MG, Barr, TP, Covic, L, and Kuliopulos, A. "Cell-Penetrating Pepducin Therapy Targeting PAR1 in Subjects With Coronary Artery Disease." Arteriosclerosis, Thrombosis, and Vascular Biology 36, no. 1 (January 2016): 189-197.  Full Text
    • Gurbel, PA, and Tantry, US. "CardioPulse: Platelet inhibitors and their differences." European heart journal 37, no. 4 (January 2016): 323-326.  Full Text
    • Tantry, US, Liu, F, Chen, G, and Gurbel, PA. "Vorapaxar in the secondary prevention of atherothrombosis." Expert review of cardiovascular therapy 13, no. 12 (December 2015): 1293-1305. (Review)  Full Text
    • Tantry, US, and Gurbel, PA. "A Bigger Look Into the "Therapeutic Window" of Platelet Reactivity to Adenosine Diphosphate." JACC. Cardiovascular interventions 8, no. 15 (December 2015): 1988-1989.  Full Text
    • Gurbel, PA, and Tantry, US. "Inhibited and Uninhibited Platelet Deposition Within a Thrombus: Does It Depend on the Antiplatelet Drug?." Arteriosclerosis, thrombosis, and vascular biology 35, no. 10 (October 2015): 2081-2082.  Full Text
    • Jeong, Y-H, Smith, SC, and Gurbel, PA. "Long-Term Use of Ticagrelor in Patients with Prior Myocardial Infarction." The New England journal of medicine 373, no. 13 (September 2015): 1273-1274. (Letter)  Full Text
    • Tricoci, P, D'Andrea, DM, Gurbel, PA, Yao, Z, Cuchel, M, Winston, B, Schott, R, Weiss, R, Blazing, MA, Cannon, L, Bailey, A, Angiolillo, DJ, Gille, A, Shear, CL, Wright, SD, and Alexander, JH. "Infusion of Reconstituted High-Density Lipoprotein, CSL112, in Patients With Atherosclerosis: Safety and Pharmacokinetic Results From a Phase 2a Randomized Clinical Trial." Journal of the American Heart Association 4, no. 8 (August 25, 2015): e002171-null.  Full Text
    • Kowalewski, M, Schulze, V, Berti, S, Waksman, R, Kubica, J, Kołodziejczak, M, Buffon, A, Suryapranata, H, Gurbel, PA, Kelm, M, Pawliszak, W, Anisimowicz, L, and Navarese, EP. "Complete revascularisation in ST-elevation myocardial infarction and multivessel disease: meta-analysis of randomised controlled trials." Heart (British Cardiac Society) 101, no. 16 (August 2015): 1309-1317.  Full Text
    • Aradi, D, Kirtane, A, Bonello, L, Gurbel, PA, Tantry, US, Huber, K, Freynhofer, MK, ten Berg, J, Janssen, P, Angiolillo, DJ, Siller-Matula, JM, Marcucci, R, Patti, G, Mangiacapra, F, Valgimigli, M, Morel, O, Palmerini, T, Price, MJ, Cuisset, T, Kastrati, A, Stone, GW, and Sibbing, D. "Bleeding and stent thrombosis on P2Y12-inhibitors: collaborative analysis on the role of platelet reactivity for risk stratification after percutaneous coronary intervention." European Heart Journal 36, no. 27 (July 2015): 1762-1771. (Review)  Full Text
    • Navarese, EP, Kolodziejczak, M, Schulze, V, Gurbel, PA, Tantry, U, Lin, Y, Brockmeyer, M, Kandzari, DE, Kubica, JM, D'Agostino, RB, Kubica, J, Volpe, M, Agewall, S, Kereiakes, DJ, and Kelm, M. "Effects of Proprotein Convertase Subtilisin/Kexin Type 9 Antibodies in Adults With Hypercholesterolemia: A Systematic Review and Meta-analysis." Annals of internal medicine 163, no. 1 (July 2015): 40-51. (Review)  Full Text
    • Baber, U, Mehran, R, Kirtane, AJ, Gurbel, PA, Christodoulidis, G, Maehara, A, Witzenbichler, B, Weisz, G, Rinaldi, MJ, Metzger, DC, Henry, TD, Cox, DA, Duffy, PL, Mazzaferri, EL, Xu, K, Parise, H, Brodie, BR, Stuckey, TD, and Stone, GW. "Prevalence and impact of high platelet reactivity in chronic kidney disease: results from the Assessment of Dual Antiplatelet Therapy with Drug-Eluting Stents registry." Circulation. Cardiovascular interventions 8, no. 6 (June 2015): e001683-.  Full Text
    • Liu, F, Tantry, US, and Gurbel, PA. "P2Y12 receptor inhibitors for secondary prevention of ischemic stroke." Expert Opinion on Pharmacotherapy 16, no. 8 (June 2015): 1149-1165. (Review)  Full Text
    • Mahla, E, Tantry, US, and Gurbel, PA. "Platelet Function Testing Before CABG is Recommended in the Guidelines: But Do We Have Enough Evidence?." Journal of interventional cardiology 28, no. 3 (June 2015): 233-235.  Full Text
    • Rafeedheen, R, Bliden, KP, Liu, F, Tantry, US, and Gurbel, PA. "Novel antiplatelet agents in cardiovascular medicine." Current treatment options in cardiovascular medicine 17, no. 6 (June 2015): 383-.  Full Text
    • Franzese, CJ, Bliden, KP, Gesheff, MG, Pandya, S, Guyer, KE, Singla, A, Tantry, US, Toth, PP, and Gurbel, PA. "Relation of fish oil supplementation to markers of atherothrombotic risk in patients with cardiovascular disease not receiving lipid-lowering therapy." The American journal of cardiology 115, no. 9 (May 2015): 1204-1211.  Full Text
    • Gurbel, PA, Kreutz, RP, Bliden, KP, and Tantry, US. "Platelet activation and pneumonia: is soluble p-selectin the right marker?." Journal of the American College of Cardiology 65, no. 14 (April 2015): 1492-1493. (Letter)  Full Text
    • Jung, JH, Tantry, US, Gurbel, PA, and Jeong, Y-H. "Current antiplatelet treatment strategy in patients with diabetes mellitus." Diabetes & Metabolism Journal 39, no. 2 (April 2015): 95-113. (Review)  Full Text
    • Gurbel, PA, Kuliopulos, A, and Tantry, US. "G-protein-coupled receptors signaling pathways in new antiplatelet drug development." Arteriosclerosis, Thrombosis, and Vascular Biology 35, no. 3 (March 2015): 500-512. (Review)  Full Text
    • Lhermusier, T, Lipinski, MJ, Tantry, US, Escarcega, RO, Baker, N, Bliden, KP, Magalhaes, MA, Ota, H, Tian, W, Pendyala, L, Minha, S, Chen, F, Torguson, R, Gurbel, PA, and Waksman, R. "Meta-analysis of direct and indirect comparison of ticagrelor and prasugrel effects on platelet reactivity." The American Journal of Cardiology 115, no. 6 (March 2015): 716-723.  Full Text
    • Gurbel, PA, Gesheff, MG, Franzese, CJ, Bliden, KP, and Tantry, US. "Is light transmittance aggregometry still a useful tool to assess pharmacodynamic effects of antiplatelet therapy?." Platelets 26, no. 6 (January 2015): 608-609. (Letter)  Full Text
    • Gurbel, PA, Navarese, EP, and Tantry, US. "What is the best anticoagulant therapy during primary percutaneous coronary intervention for acute myocardial infarction?." Polskie Archiwum Medycyny Wewnetrznej 125, no. 6 (January 2015): 461-470. (Review)
    • Lee, K, Yoo, S-Y, Suh, J, Park, KH, Park, Y, Tantry, US, Park, K-S, Han, SH, Kang, WC, Shin, D-H, Lee, C, Choi, SW, Lee, J-H, Cho, YH, Lee, N-H, Jeong, MH, Ahn, Y, Kubica, J, Gurbel, PA, Park, J-H, and Jeong, Y-H. "Efficacy of cilostazol on inhibition of platelet aggregation, inflammation and myonecrosis in acute coronary syndrome patients undergoing percutaneous coronary intervention: The ACCEL-LOADING-ACS (ACCELerated Inhibition of Platelet Aggregation, Inflammation and Myonecrosis by Adjunctive Cilostazol Loading in Patients With Acute Coronary Syndrome) study." International Journal of Cardiology 190 (January 2015): 370-375. (Letter)  Full Text
    • Kahn, SR, Shapiro, S, Ducruet, T, Wells, PS, Rodger, MA, Kovacs, MJ, Anderson, D, Tagalakis, V, Morrison, DR, Solymoss, S, Miron, M-J, Yeo, E, Smith, R, Schulman, S, Kassis, J, Kearon, C, Chagnon, I, Wong, T, Demers, C, Hanmiah, R, Kaatz, S, Selby, R, Rathbun, S, Desmarais, S, Opatrny, L, Ortel, TL, Galanaud, J-P, and Ginsberg, JS. "Graduated compression stockings to treat acute leg pain associated with proximal DVT. A randomised controlled trial." Thrombosis and haemostasis 112, no. 6 (December 2014): 1137-1141.  Full Text
    • Park, Y, Jeong, Y-H, Tantry, US, Ahn, JH, Kim, KH, Koh, J-S, Park, J-R, Hwang, S-J, Kwak, CH, Hwang, J-Y, and Gurbel, PA. "Effect of adjunctive dipyridamole to DAPT on platelet function profiles in stented patients with high platelet reactivity. The result of the ACCEL-DIP Study." Thrombosis and Haemostasis 112, no. 6 (December 2014): 1198-1208.  Full Text
    • Tantry, US, Gesheff, M, Liu, F, Bliden, KP, and Gurbel, PA. "Resistance to antiplatelet drugs: what progress has been made?." Expert Opinion on Pharmacotherapy 15, no. 17 (December 2014): 2553-2564. (Review)  Full Text
    • Lev, EI, Bliden, KP, Jeong, Y-H, Pandya, S, Kang, K, Franzese, C, Tantry, US, and Gurbel, PA. "Influence of race and sex on thrombogenicity in a large cohort of coronary artery disease patients." Journal of the American Heart Association 3, no. 5 (October 20, 2014): e001167-null.  Full Text
    • Alexopoulos, D, Xanthopoulou, I, Storey, RF, Bliden, KP, Tantry, US, Angiolillo, DJ, and Gurbel, PA. "Platelet reactivity during ticagrelor maintenance therapy: a patient-level data meta-analysis." American Heart Journal 168, no. 4 (October 2014): 530-536. (Review)  Full Text
    • Gesheff, MG, Franzese, CJ, Bliden, KP, Contino, CJ, Rafeedheen, R, Tantry, US, and Gurbel, PA. "Review of pharmacokinetic and pharmacodynamic modeling and safety of proton pump inhibitors and aspirin." Expert Review of Clinical Pharmacology 7, no. 5 (September 2014): 645-653. (Review)  Full Text
    • Gurbel, PA, Bergmeijer, TO, Tantry, US, ten Berg, JM, Angiolillo, DJ, James, S, Lindahl, TL, Svensson, P, Jakubowski, JA, Brown, PB, Duvvuru, S, Sundseth, S, Walker, JR, Small, D, Moser, BA, Winters, KJ, and Erlinge, D. "The effect of CYP2C19 gene polymorphisms on the pharmacokinetics and pharmacodynamics of prasugrel 5-mg, prasugrel 10-mg and clopidogrel 75-mg in patients with coronary artery disease." Thrombosis and Haemostasis 112, no. 3 (September 2014): 589-597.  Full Text
    • Bliden, KP, Singla, A, Gesheff, MG, Toth, PP, Tabrizchi, A, Ens, G, Guyer, K, Singh, M, Franzese, CJ, Stapleton, D, Tantry, US, and Gurbel, PA. "Statin therapy and thromboxane generation in patients with coronary artery disease treated with high-dose aspirin." Thrombosis and Haemostasis 112, no. 2 (August 2014): 323-331.  Full Text
    • Gurbel, PA, Baker, BA, Bailey, WL, Bliden, KP, and Tantry, US. "Unravelling the smokers' paradox: cigarette smoking, high-risk coronary artery disease and enhanced clinical efficacy of oral P2Y₁₂ inhibitors." Thrombosis and Haemostasis 111, no. 6 (June 2014): 1187-1190. (Letter,Review)  Full Text
    • Gurbel, PA, Rafeedheen, R, and Tantry, US. "Update: Acute coronary syndromes (V). Personalized antiplatelet therapy." Revista Espanola De Cardiologia (English Ed.) 67, no. 6 (June 2014): 480-487. (Review)  Full Text
    • Gurbel, PA, Rafeedheen, R, and Tantry, US. "Tratamiento antiagregante plaquetario personalizado." Revista Española De Cardiología 67, no. 6 (June 2014): 480-487.  Full Text
    • Koh, J-S, Kim, I-S, Tantry, US, Yoon, S-E, Park, Y, Cho, SY, Lee, E-J, Park, JR, Hwang, S-J, Kwak, CH, Hwang, J-Y, Gurbel, PA, and Jeong, Y-H. "Pharmacodynamic efficacy and safety of adjunctive cilostazol loading to clopidogrel and aspirin loading: the results of the ACCEL-LOADING (Accelerated Platelet Inhibition by Cilostazol Loading) study." International Journal of Cardiology 174, no. 1 (June 2014): 129-132. (Letter)  Full Text
    • Erlinge, D, James, S, Duvvuru, S, Jakubowski, JA, Wagner, H, Varenhorst, C, Tantry, US, Brown, PB, Small, D, Moser, BA, Sundseth, SS, Walker, JR, Winters, KJ, and Gurbel, PA. "Clopidogrel metaboliser status based on point-of-care CYP2C19 genetic testing in patients with coronary artery disease." Thrombosis and Haemostasis 111, no. 5 (May 2014): 943-950.  Full Text
    • Kubica, J, Kozinski, M, Navarese, EP, Tantry, U, Kubica, A, Siller-Matula, JM, Jeong, Y-H, Fabiszak, T, Andruszkiewicz, A, and Gurbel, PA. "Cangrelor: an emerging therapeutic option for patients with coronary artery disease." Curr Med Res Opin 30, no. 5 (May 2014): 813-828. (Review)  Full Text  Link to Item
    • Angiolillo, DJ, Curzen, N, Gurbel, P, Vaitkus, P, Lipkin, F, Li, W, Jakubowski, JA, Zettler, M, Effron, MB, and Trenk, D. "Pharmacodynamic evaluation of switching from ticagrelor to prasugrel in patients with stable coronary artery disease: Results of the SWAP-2 Study (Switching Anti Platelet-2)." Journal of the American College of Cardiology 63, no. 15 (April 2014): 1500-1509.  Full Text
    • Gurbel, PA, Bliden, KP, and Tantry, US. "Letter by Grbel et al regarding article, "administration of a loading dose has no additive effect on platelet aggregation during the switch from ongoing clopidogrel treatment to ticagrelor in patients with acute coronary syndrome"." Circulation. Cardiovascular interventions 7, no. 2 (April 2014): 273-. (Letter)  Full Text
    • Gurbel, PA, Mahla, E, and Tantry, US. "The enigmatic search for optimal DAPT duration." European Heart Journal 35, no. 15 (April 2014): 951-954.  Full Text
    • Jeong, Y-H, Bliden, KP, Shuldiner, AR, Tantry, US, and Gurbel, PA. "Thrombin-induced platelet-fibrin clot strength: relation to high on-clopidogrel platelet reactivity, genotype, and post-percutaneous coronary intervention outcomes." Thrombosis and Haemostasis 111, no. 4 (April 2014): 713-724.  Full Text
    • Gouya, G, Arrich, J, Wolzt, M, Huber, K, Verheugt, FWA, Gurbel, PA, Pirker-Kees, A, and Siller-Matula, JM. "Antiplatelet treatment for prevention of cerebrovascular events in patients with vascular diseases: a systematic review and meta-analysis." Stroke 45, no. 2 (February 2014): 492-503. (Review)  Full Text
    • Gurbel, PA, and Tantry, US. "Antiplatelet and anticoagulant agents in heart failure: current status and future perspectives." JACC. Heart failure 2, no. 1 (February 2014): 1-14. (Review)  Full Text
    • Ahn, J-H, Tantry, US, Kim, K-H, Gurbel, P, and Jeong, Y-H. "PRASFIT-ACS: Important Evidence Against a “One-Guideline-Fits-All-Races” Approach to Antiplatelet Therapy." Circulation Journal 78, no. 10 (2014): 2563-2563.  Full Text
    • Cornel, JH, Ohman, EM, Neely, B, Clemmensen, P, Sritara, P, Zamoryakhin, D, Armstrong, PW, Prabhakaran, D, White, HD, Fox, KAA, Gurbel, PA, and Roe, MT. "Impact of smoking status on platelet function and clinical outcomes with prasugrel vs. clopidogrel in patients with acute coronary syndromes managed without revascularization: Insights from the TRILOGY ACS trial." American Heart Journal 168, no. 1 (January 1, 2014).  Full Text
    • Park, Y, Jung, JM, Tantry, US, Kim, K, Koh, JS, Park, JR, Hwang, S-J, Kwak, CH, Hwang, J-Y, Kim, S, Gurbel, PA, and Jeong, Y-H. "Pharmacodynamic effects of cilostazol versus clopidogrel in stented patients under proton pump inhibitor co-administration: the ACCEL-PARAZOL study." Journal of Atherosclerosis and Thrombosis 21, no. 11 (January 2014): 1121-1139.  Full Text
    • Tantry, US, Jeong, Y-H, and Gurbel, PA. "The clopidogrel-statin interaction." Circulation Journal : Official Journal of the Japanese Circulation Society 78, no. 3 (January 2014): 592-594. (Review)  Full Text
    • Kalra, K, Franzese, CJ, Gesheff, MG, Lev, EI, Pandya, S, Bliden, KP, Tantry, US, and Gurbel, PA. "Pharmacology of antiplatelet agents." Current Atherosclerosis Reports 15, no. 12 (December 1, 2013).  Full Text
    • Tantry, US, Bonello, L, Aradi, D, Price, MJ, Jeong, Y-H, Angiolillo, DJ, Stone, GW, Curzen, N, Geisler, T, Ten Berg, J, Kirtane, A, Siller-Matula, J, Mahla, E, Becker, RC, Bhatt, DL, Waksman, R, Rao, SV, Alexopoulos, D, Marcucci, R, Reny, J-L, Trenk, D, Sibbing, D, Gurbel, PA, and Working Group on On-Treatment Platelet Reactivity, . "Consensus and update on the definition of on-treatment platelet reactivity to adenosine diphosphate associated with ischemia and bleeding." Journal of the American College of Cardiology 62, no. 24 (December 2013): 2261-2273.  Full Text
    • Bliden, KP, Brener, M, Gesheff, MG, Franzese, CJ, Tabrizchi, A, Tantry, U, and Gurbel, PA. "PA tablets: investigational compounds combining aspirin and omeprazole for cardioprotection." Future Cardiol 9, no. 6 (November 2013): 785-797. (Review)  Full Text  Link to Item
    • Tantry, US, Mahla, E, Gesheff, MG, and Gurbel, PA. "Importance of measurement of platelet reactivity to ADP in patients with coronary artery disease: an historical account." Expert Rev Cardiovasc Ther 11, no. 11 (November 2013): 1547-1556. (Review)  Full Text  Link to Item
    • Gurbel, PA, and Tantry, US. "The Role of Platelet Function Testing in Risk Stratification and Clinical Decision-Making." Interventional Cardiology Clinics 2, no. 4 (October 2013): 607-614.  Full Text
    • Jeong, Y-H, Tantry, US, Min, JH, Park, Y, Navarese, EP, Koh, J-S, Park, JR, Hwang, S-J, Kho, E-H, Bliden, KP, Kwak, CH, Hwang, J-Y, Kim, S, and Gurbel, PA. "Influence of platelet reactivity and inflammation on peri-procedural myonecrosis in East Asian patients undergoing elective percutaneous coronary intervention." Int J Cardiol 168, no. 1 (September 20, 2013): 427-435.  Full Text  Link to Item
    • Doraiswamy, VA, Slepian, MJ, Gesheff, MG, Tantry, US, and Gurbel, PA. "Potential role of oral anticoagulants in the treatment of patients with coronary artery disease: focus on dabigatran." Expert Rev Cardiovasc Ther 11, no. 9 (September 2013): 1259-1267. (Review)  Full Text  Link to Item
    • Curzen, N, Gurbel, PA, Myat, A, Bhatt, DL, and Redwood, SR. "What is the optimum adjunctive reperfusion strategy for primary percutaneous coronary intervention?." Lancet (London, England) 382, no. 9892 (August 2013): 633-643. (Review)  Full Text
    • Erlinge, D, Gurbel, PA, James, S, Lindahl, TL, Svensson, P, Ten Berg, JM, Foley, DP, Wagner, H, Brown, PB, Luo, J, Zhou, C, Moser, BA, Jakubowski, JA, Small, DS, Winters, KJ, and Angiolillo, DJ. "Prasugrel 5 mg in the very elderly attenuates platelet inhibition but maintains noninferiority to prasugrel 10 mg in nonelderly patients: the GENERATIONS trial, a pharmacodynamic and pharmacokinetic study in stable coronary artery disease patients." Journal of the American College of Cardiology 62, no. 7 (August 2013): 577-583.  Full Text
    • Gurbel, PA, Bliden, KP, Logan, DK, Kereiakes, DJ, Lasseter, KC, White, A, Angiolillo, DJ, Nolin, TD, Maa, J-F, Bailey, WL, Jakubowski, JA, Ojeh, CK, Jeong, Y-H, Tantry, US, and Baker, BA. "The influence of smoking status on the pharmacokinetics and pharmacodynamics of clopidogrel and prasugrel: the PARADOX study." Journal of the American College of Cardiology 62, no. 6 (August 2013): 505-512.  Full Text
    • Myat, A, Ahmad, Y, Haldar, S, Tantry, US, Redwood, SR, Gurbel, PA, and Lip, GY. "Is bleeding a necessary evil? The inherent risk of antithrombotic pharmacotherapy used for stroke prevention in atrial fibrillation." Expert Rev Cardiovasc Ther 11, no. 8 (August 2013): 1029-1049. (Review)  Full Text  Link to Item
    • Obonska, K, Navarese, EP, Lansky, A, Tarantini, G, Rossini, R, Kozinski, M, Musumeci, G, Di Pasquale, G, Górny, B, Szczesniak, A, Kowalewski, M, Gurbel, PA, and Kubica, J. "Low-dose of oral factor Xa inhibitors in patients with a recent acute coronary syndrome: a systematic review and meta-analysis of randomized trials." Atherosclerosis 229, no. 2 (August 2013): 482-488. (Review)  Full Text  Link to Item
    • Stone, GW, Witzenbichler, B, Weisz, G, Rinaldi, MJ, Neumann, F-J, Metzger, DC, Henry, TD, Cox, DA, Duffy, PL, Mazzaferri, E, Gurbel, PA, Xu, K, Parise, H, Kirtane, AJ, Brodie, BR, Mehran, R, Stuckey, TD, and ADAPT-DES Investigators, . "Platelet reactivity and clinical outcomes after coronary artery implantation of drug-eluting stents (ADAPT-DES): a prospective multicentre registry study." Lancet (London, England) 382, no. 9892 (August 2013): 614-623.  Full Text
    • Tantry, US, and Gurbel, PA. "The next 10 years in personalized medicine in cardiology." Expert Rev Cardiovasc Ther 11, no. 8 (August 2013): 933-935.  Full Text  Link to Item
    • Gurbel, PA, and Tantry, US. "P2Y12 Receptor Blockade and Myocardial Perfusion." Jacc. Cardiovascular Interventions 6, no. 7 (July 2013): 684-686.  Full Text
    • Kim, I-S, Jeong, Y-H, Tantry, US, Park, Y, Lee, D-H, Bliden, KP, Koh, J-S, Park, JR, Jang, J-S, Hwang, S-J, Koh, E-H, Kwak, CH, Hwang, J-Y, Kim, S, and Gurbel, PA. "Relation between the vasodilator-stimulated phosphoprotein phosphorylation assay and light transmittance aggregometry in East Asian patients after high-dose clopidogrel loading." American Heart Journal 166, no. 1 (July 2013): 95-103.  Full Text
    • Jeong, Y-H, Abadilla, KA, Tantry, US, Park, Y, Koh, J-S, Kwak, CH, Hwang, J-Y, and Gurbel, PA. "Influence of CYP2C19*2 and *3 loss-of-function alleles on the pharmacodynamic effects of standard- and high-dose clopidogrel in East Asians undergoing percutaneous coronary intervention: the results of the ACCEL-DOUBLE-2N3 study." Journal of Thrombosis and Haemostasis : Jth 11, no. 6 (June 2013): 1194-1197. (Letter)  Full Text
    • Gurbel, PA, and Tantry, US. "Triple antithrombotic therapy with prasugrel in the stented patient: concern for more bleeding." J Am Coll Cardiol 61, no. 20 (May 21, 2013): 2067-2069.  Full Text  Link to Item
    • Bliden, KP, Baker, BA, Nolin, TD, Jeong, Y-H, Bailey, WL, Tantry, US, and Gurbel, PA. "Thienopyridine efficacy and cigarette smoking status." Am Heart J 165, no. 5 (May 2013): 693-703. (Review)  Full Text  Link to Item
    • Dahlen, JR, Price, MJ, Parise, H, and Gurbel, PA. "Evaluating the clinical usefulness of platelet function testing: considerations for the proper application and interpretation of performance measures." Thromb Haemost 109, no. 5 (May 2013): 808-816. (Review)  Full Text  Link to Item
    • Swiger, KJ, Yousuf, O, Bliden, KP, Tantry, US, and Gurbel, PA. "Cigarette smoking and clopidogrel interaction." Current Cardiology Reports 15, no. 5 (May 2013): 361-null. (Review)  Full Text
    • Lewis, JP, Ryan, K, O'Connell, JR, Horenstein, RB, Damcott, CM, Gibson, Q, Pollin, TI, Mitchell, BD, Beitelshees, AL, Pakzy, R, Tanner, K, Parsa, A, Tantry, US, Bliden, KP, Post, WS, Faraday, N, Herzog, W, Gong, Y, Pepine, CJ, Johnson, JA, Gurbel, PA, and Shuldiner, AR. "Genetic variation in PEAR1 is associated with platelet aggregation and cardiovascular outcomes." Circulation. Cardiovascular Genetics 6, no. 2 (April 2013): 184-192.  Full Text
    • Navarese, EP, Austin, D, Gurbel, PA, Andreotti, F, Tantry, U, James, S, Buffon, A, Kozinski, M, Obonska, K, Bliden, K, Jeong, Y-H, Kubica, J, and Kunadian, V. "Drug-coated balloons in treatment of in-stent restenosis: a meta-analysis of randomised controlled trials." Clin Res Cardiol 102, no. 4 (April 2013): 279-287.  Full Text  Link to Item
    • Tantry, US, Jeong, Y-H, Navarese, EP, Kubica, J, and Gurbel, PA. "Influence of genetic polymorphisms on platelet function, response to antiplatelet drugs and clinical outcomes in patients with coronary artery disease." Expert Review of Cardiovascular Therapy 11, no. 4 (April 2013): 447-462.  Full Text
    • Gurbel, PA, Bliden, KP, Fort, JG, Jeong, Y-H, Shuldiner, A, Chai, S, Gesheff, T, Antonino, M, Gesheff, M, Zhang, Y, and Tantry, US. "Spaced administration of PA32540 and clopidogrel results in greater platelet inhibition than synchronous administration of enteric-coated aspirin and enteric-coated omeprazole and clopidogrel." American Heart Journal 165, no. 2 (February 2013): 176-182.  Full Text
    • Saucedo, JF, Angiolillo, DJ, DeRaad, R, Frelinger, AL, Gurbel, PA, Costigan, TM, Jakubowski, JA, Ojeh, CK, Duvvuru, S, Effron, MB, and SWAP Investigators, . "Decrease in high on-treatment platelet reactivity (HPR) prevalence on switching from clopidogrel to prasugrel: insights from the switching anti-platelet (SWAP) study." Thrombosis and Haemostasis 109, no. 2 (February 2013): 347-355.  Full Text
    • Grześk, G, Kozinski, M, Tantry, US, Wicinski, M, Fabiszak, T, Navarese, EP, Grzesk, E, Jeong, Y-H, Gurbel, PA, and Kubica, J. "High-dose, but not low-dose, aspirin impairs anticontractile effect of ticagrelor following ADP stimulation in rat tail artery smooth muscle cells." Biomed Research International 2013 (January 2013): 928271-null.  Full Text
    • Jeong, Y-H, Bliden, KP, Antonino, MJ, Tantry, US, and Gurbel, PA. "Usefulness of thrombelastography platelet mapping assay to measure the antiplatelet effect of P2Y(12) receptor inhibitors and high on-treatment platelet reactivity." Platelets 24, no. 2 (2013): 166-169. (Letter)  Full Text  Link to Item
    • Lewis, JP, Horenstein, RB, Ryan, K, O'Connell, JR, Gibson, Q, Mitchell, BD, Tanner, K, Chai, S, Bliden, KP, Tantry, US, Peer, CJ, Figg, WD, Spencer, SD, Pacanowski, MA, Gurbel, PA, and Shuldiner, AR. "The functional G143E variant of carboxylesterase 1 is associated with increased clopidogrel active metabolite levels and greater clopidogrel response." Pharmacogenetics and Genomics 23, no. 1 (January 2013): 1-8.  Full Text
    • Singla, A, Bliden, KP, Jeong, Y-H, Abadilla, K, Antonino, MJ, Muse, WC, Mathew, DP, Bailon, O, Tantry, US, and Gurbel, PA. "Platelet reactivity and thrombogenicity in postmenopausal women." Menopause 20, no. 1 (January 2013): 57-63.  Full Text  Link to Item
    • Swiger, KJ, Yousuf, O, Bliden, KP, Tantry, US, and Gurbel, PA. "Cigarette smoking and clopidogrel interaction." Current Cardiology Reports 15, no. 5 (January 1, 2013).  Full Text
    • Tantry, US, and Gurbel, PA. "Antiplatelet drug resistance and variability in response: the role of antiplatelet therapy monitoring." Current Pharmaceutical Design 19, no. 21 (January 2013): 3795-3815. (Review)  Full Text
    • Gurbel, PA, Erlinge, D, Ohman, EM, Neely, B, Neely, M, Goodman, SG, Huber, K, Chan, MY, Cornel, JH, Brown, E, Zhou, C, Jakubowski, JA, White, HD, Fox, KA, Prabhakaran, D, Armstrong, PW, Tantry, US, and Roe, MT. "Platelet Function During Extended Prasugrel and Clopidogrel Therapy for Patients With ACS Treated Without Revascularization: The TRILOGY ACS Platelet Function Substudy." Jama (November 2012): 1-10.  Full Text
    • Jeong, Y-H, Tantry, US, Park, Y, Kwon, TJ, Park, JR, Hwang, S-J, Bliden, KP, Koh, E-H, Kwak, CH, Hwang, J-Y, Kim, S, and Gurbel, PA. "Pharmacodynamic effect of cilostazol plus standard clopidogrel versus double-dose clopidogrel in patients with type 2 diabetes undergoing percutaneous coronary intervention." Diabetes Care 35, no. 11 (November 2012): 2194-2197.  Full Text
    • Gurbel, PA, Nolin, TD, and Tantry, US. "Influence of smoking on treatment with clopidogrel - In reply." Jama Journal of the American Medical Association 308, no. 13 (October 3, 2012): 1323-1324. (Letter)  Full Text
    • Roe, MT, Armstrong, PW, Fox, KAA, White, HD, Prabhakaran, D, Goodman, SG, Cornel, JH, Bhatt, DL, Clemmensen, P, Martinez, F, Ardissino, D, Nicolau, JC, Boden, WE, Gurbel, PA, Ruzyllo, W, Dalby, AJ, McGuire, DK, Leiva-Pons, JL, Parkhomenko, A, Gottlieb, S, Topacio, GO, Hamm, C, Pavlides, G, Goudev, AR, Oto, A, Tseng, C-D, Merkely, B, Gasparovic, V, Corbalan, R, Cinteză, M, McLendon, RC, Winters, KJ, Brown, EB, Lokhnygina, Y, Aylward, PE, Huber, K, Hochman, JS, Ohman, EM, and TRILOGY ACS Investigators, . "Prasugrel versus clopidogrel for acute coronary syndromes without revascularization." The New England Journal of Medicine 367, no. 14 (October 2012): 1297-1309.  Full Text
    • Navarese, EP, Gurbel, P, Tantry, U, Obonska, K, Sukiennik, A, and Kubica, J. "Caution in interpreting the findings from small observational studies." International journal of cardiology 160, no. 1 (September 2012): 71-. (Letter)  Full Text
    • Park, Y, Jeong, Y-H, Tantry, US, Ahn, JH, Kwon, TJ, Park, JR, Hwang, S-J, Gho, E-H, Bliden, KP, Kwak, CH, Hwang, J-Y, Kim, S, and Gurbel, PA. "Accelerated platelet inhibition by switching from atorvastatin to a non-CYP3A4-metabolized statin in patients with high platelet reactivity (ACCEL-STATIN) study." European Heart Journal 33, no. 17 (September 2012): 2151-2162.  Full Text
    • Jeong, Y-H, Bliden, KP, Park, Y, Tantry, US, and Gurbel, PA. "Pharmacogenetic guidance for antiplatelet treatment." Lancet 380, no. 9843 (August 25, 2012): 725-. (Letter)  Full Text  Link to Item
    • Antonino, MJ, Jeong, Y-H, Tantry, US, Bliden, KP, and Gurbel, PA. "Role of genotype-based personalized antiplatelet therapy in the era of potent P2Y₁₂ receptor inhibitors." Expert Rev Cardiovasc Ther 10, no. 8 (August 2012): 1011-1022. (Review)  Full Text  Link to Item
    • Jeong, Y-H, Tantry, US, and Gurbel, PA. "Importance of potent P2Y(12) receptor blockade in acute myocardial infarction: focus on prasugrel." Expert Opinion on Pharmacotherapy 13, no. 12 (August 2012): 1771-1796. (Review)  Full Text
    • Gurbel, PA, Roe, MT, Jakubowski, JA, Shah, S, Erlinge, D, Goodman, SG, Huber, K, Chan, MY, Cornel, JH, Tantry, US, and Ohman, EM. "Translational platelet research in patients with coronary artery disease: what are the major knowledge gaps?." Thrombosis and Haemostasis 108, no. 1 (July 2012): 12-20. (Review)  Full Text
    • Jeong, Y-H, Bliden, KP, Antonino, MJ, Park, K-S, Tantry, US, and Gurbel, PA. "Usefulness of the VerifyNow P2Y12 assay to evaluate the antiplatelet effects of ticagrelor and clopidogrel therapies." American Heart Journal 164, no. 1 (July 2012): 35-42.  Full Text
    • Reny, J-L, Combescure, C, Daali, Y, Fontana, P, and PON1 Meta-Analysis Group, . "Influence of the paraoxonase-1 Q192R genetic variant on clopidogrel responsiveness and recurrent cardiovascular events: a systematic review and meta-analysis." Journal of Thrombosis and Haemostasis : Jth 10, no. 7 (July 2012): 1242-1251. (Review)  Full Text
    • Tantry, US, Navarese, EP, Kubica, J, Jeong, YH, and Gurbel, PA. "Ticagrelor in the treatment of coronary artery disease patients." Clinical Practice 9, no. 4 (July 1, 2012): 373-390. (Review)  Full Text
    • Angiolillo, DJ, Welsh, RC, Trenk, D, Neumann, F-J, Conley, PB, McClure, MW, Stephens, G, Kochman, J, Jennings, LK, Gurbel, PA, Wójcik, J, Dabrowski, M, Saucedo, JF, Stumpf, J, Buerke, M, Broderick, S, Harrington, RA, and Rao, SV. "Pharmacokinetic and pharmacodynamic effects of elinogrel: results of the platelet function substudy from the intravenous and oral administration of elinogrel to evaluate tolerability and efficacy in nonurgent percutaneous coronary intervention patients (INNOVATE-PCI) trial." Circulation. Cardiovascular Interventions 5, no. 3 (June 2012): 347-356.  Full Text
    • Gurbel, PA, Nolin, TD, and Tantry, US. "Clopidogrel efficacy and cigarette smoking status." Jama 307, no. 23 (June 2012): 2495-2496.  Full Text
    • Husted, SE, Storey, RF, Bliden, K, Tantry, US, Høimark, L, Butler, K, Wei, C, Teng, R, and Gurbel, PA. "Pharmacokinetics and pharmacodynamics of ticagrelor in patients with stable coronary artery disease: results from the ONSET-OFFSET and RESPOND studies." Clinical Pharmacokinetics 51, no. 6 (June 2012): 397-409.  Full Text
    • Mahla, E, Suarez, TA, Bliden, KP, Sequeira, AJ, Cho, P, Sell, J, Fan, J, Antonino, MJ, Tantry, US, Gurbel, PA, Rehak, P, and Metzler, H. "Response to letter regarding article, "platelet function measurement-based strategy to reduce bleeding and waiting time in clopidogrel-treated patients undergoing coronary artery bypass graft surgery: The timing based on platelet function strategy to reduce clopidogrel-associated bleeding related to CABG (TARGET-CABG) study"." Circulation: Cardiovascular Interventions 5, no. 3 (June 1, 2012). (Letter)  Full Text
    • Welsh, RC, Rao, SV, Zeymer, U, Thompson, VP, Huber, K, Kochman, J, McClure, MW, Gretler, DD, Bhatt, DL, Gibson, CM, Angiolillo, DJ, Gurbel, PA, Berdan, LG, Paynter, G, Leonardi, S, Madan, M, French, WJ, Harrington, RA, and INNOVATE-PCI Investigators, . "A randomized, double-blind, active-controlled phase 2 trial to evaluate a novel selective and reversible intravenous and oral P2Y12 inhibitor elinogrel versus clopidogrel in patients undergoing nonurgent percutaneous coronary intervention: the INNOVATE-PCI trial." Circulation. Cardiovascular Interventions 5, no. 3 (June 2012): 336-346.  Full Text
    • Gurbel, PA, Ohman, EM, Jeong, Y-H, and Tantry, US. "Toward a therapeutic window for antiplatelet therapy in the elderly." European Heart Journal 33, no. 10 (May 2012): 1187-1189.  Full Text
    • Navarese, EP, Buffon, A, Andreotti, F, Gurbel, PA, Kozinski, M, Kubica, A, Musumeci, G, Cremonesi, A, Tavazzi, L, Kubica, J, and Castriota, F. "Adenosine improves post-procedural coronary flow but not clinical outcomes in patients with acute coronary syndrome: a meta-analysis of randomized trials." Atherosclerosis 222, no. 1 (May 2012): 1-7. (Review)  Full Text  Link to Item
    • Mahla, E, Suarez, TA, Bliden, KP, Rehak, P, Metzler, H, Sequeira, AJ, Cho, P, Sell, J, Fan, J, Antonino, MJ, Tantry, US, and Gurbel, PA. "Platelet function measurement-based strategy to reduce bleeding and waiting time in clopidogrel-treated patients undergoing coronary artery bypass graft surgery: the timing based on platelet function strategy to reduce clopidogrel-associated bleeding related to CABG (TARGET-CABG) study." Circulation. Cardiovascular Interventions 5, no. 2 (April 2012): 261-269.  Full Text
    • Tantry, US, Navarese, EP, and Gurbel, PA. "Does gender have an influence on platelet function and the efficacy of oral antiplatelet therapy?." Interventional Cardiology Clinics 1, no. 2 (April 1, 2012): 223-230. (Review)  Full Text
    • Gurbel, PA, and Tantry, US. "Do platelet function testing and genotyping improve outcome in patients treated with antithrombotic agents?: platelet function testing and genotyping improve outcome in patients treated with antithrombotic agents." Circulation 125, no. 10 (March 2012): 1276-1287.  Full Text
    • Jeong, Y-H, Bliden, KP, Tantry, US, and Gurbel, PA. "High on-treatment platelet reactivity assessed by various platelet function tests: is the consensus-defined cut-off of VASP-P platelet reactivity index too low?." J Thromb Haemost 10, no. 3 (March 2012): 487-489. (Letter)  Full Text  Link to Item
    • Tantry, US, Jeong, Y-H, Navarese, EP, and Gurbel, PA. "Platelet function measurement in elective percutaneous coronary intervention patients: exploring the concept of a P2Y₁₂ inhibitor therapeutic window." JACC Cardiovasc Interv 5, no. 3 (March 2012): 290-292.  Full Text  Link to Item
    • Jeong, Y-H, Park, Y, Bliden, KP, Tantry, US, and Gurbel, PA. "High platelet reactivity to multiple agonists during aspirin and clopidogrel treatment is indicative of a global hyperreactive platelet phenotype." Heart 98, no. 4 (February 2012): 343-. (Letter)  Full Text  Link to Item
    • Gurbel, PA, Bliden, KP, Antonino, MJ, Gesheff, T, Cummings, CC, Dubois, BV, Herzog, WR, and Tantry, US. "Time dependence of clopidogrel loading effect: platelet activation versus platelet aggregation." Thrombosis Research 129, no. 1 (January 2012): 1-2.  Full Text
    • Kubica, J, Koziński, M, Navarese, EP, Tantry, US, Grześk, G, Fabiszak, T, Kubica, A, Świątkiewicz, I, Bliden, KP, and Gurbel, PA. "Updated evidence on intracoronary abciximab in ST-elevation myocardial infarction: a systematic review and meta-analysis of randomized clinical trials." Cardiology Journal 19, no. 3 (January 2012): 230-242. (Review)
    • Navarese, EP, Kozinski, M, Obonska, K, Margheri, M, Gurbel, PA, Kubica, J, and De Luca, G. "Clinical efficacy and safety of intracoronary vs. intravenous abciximab administration in STEMI patients undergoing primary percutaneous coronary intervention: a meta-analysis of randomized trials." Platelets 23, no. 4 (January 2012): 274-281.  Full Text
    • Tantry, US, Budaj, A, and Gurbel, PA. "Antiplatelet therapy beyond 2012: role of personalized medicine." Polskie Archiwum Medycyny Wewnetrznej 122, no. 6 (January 2012): 298-305. (Review)
    • Jeong, Y-H, Bliden, KP, Tantry, US, and Gurbel, PA. "The role of platelet function testing and genotyping in the stented patient treated with clopidogrel." J Am Coll Cardiol 58, no. 25 (December 13, 2011): 2701-2702. (Letter)  Full Text  Link to Item
    • Gurbel, PA, Bliden, KP, Fort, J, Zhang, Y, Plachetka, JR, Antonino, M, Gesheff, M, and Tantry, US. "Pharmacodynamic evaluation of clopidogrel plus PA32540: the Spaced PA32540 With Clopidogrel Interaction Gauging (SPACING) study." Clinical Pharmacology and Therapeutics 90, no. 6 (December 2011): 860-866.  Full Text
    • Jeong, Y-H, Tantry, US, Kim, I-S, Koh, J-S, Kwon, TJ, Park, Y, Hwang, S-J, Bliden, KP, Kwak, CH, Hwang, J-Y, and Gurbel, PA. "Effect of CYP2C19*2 and *3 loss-of-function alleles on platelet reactivity and adverse clinical events in East Asian acute myocardial infarction survivors treated with clopidogrel and aspirin." Circulation. Cardiovascular Interventions 4, no. 6 (December 2011): 585-594.  Full Text
    • Navarese, EP, Kubica, J, and Gurbel, PA. ""Sirolimus or paclitaxel drug eluting stent in left main disease: the winner is.. "." Int J Cardiol 152, no. 3 (November 3, 2011): 387-. (Letter)  Full Text  Link to Item
    • Gurbel, PA, Jeong, Y-H, and Tantry, US. "Vorapaxar: a novel protease-activated receptor-1 inhibitor." Expert Opin Investig Drugs 20, no. 10 (October 2011): 1445-1453. (Review)  Full Text  Link to Item
    • Lewis, JP, Fisch, AS, Ryan, K, O'Connell, JR, Gibson, Q, Mitchell, BD, Shen, H, Tanner, K, Horenstein, RB, Pakzy, R, Tantry, US, Bliden, KP, Gurbel, PA, and Shuldiner, AR. "Paraoxonase 1 (PON1) gene variants are not associated with clopidogrel response." Clinical Pharmacology and Therapeutics 90, no. 4 (October 2011): 568-574.  Full Text
    • Navarese, EP, De Luca, G, Castriota, F, Kozinski, M, Gurbel, PA, Gibson, CM, Andreotti, F, Buffon, A, Siller-Matula, JM, Sukiennik, A, De Servi, S, and Kubica, J. "Low-molecular-weight heparins vs. unfractionated heparin in the setting of percutaneous coronary intervention for ST-elevation myocardial infarction: a meta-analysis." J Thromb Haemost 9, no. 10 (October 2011): 1902-1915.  Full Text  Link to Item
    • Tantry, US, and Gurbel, PA. "Assessment of oral antithrombotic therapy by platelet function testing." Nature Reviews. Cardiology 8, no. 10 (October 2011): 572-579. (Review)  Full Text
    • Gurbel, PA, Jeong, Y-H, and Tantry, US. "Cutaneous clopidogrel hypersensitivity: give steroids and do not stop the clopidogrel." Journal of the American College of Cardiology 58, no. 14 (September 2011): 1455-1456.  Full Text
    • Storey, RF, Bliden, KP, Ecob, R, Karunakaran, A, Butler, K, Wei, C, Tantry, U, and Gurbel, PA. "Earlier recovery of platelet function after discontinuation of treatment with ticagrelor compared with clopidogrel in patients with high antiplatelet responses." Journal of Thrombosis and Haemostasis : Jth 9, no. 9 (September 2011): 1730-1737.  Full Text
    • Gurbel, PA, Mahla, E, and Tantry, US. "Peri-operative platelet function testing: the potential for reducing ischaemic and bleeding risks." Thromb Haemost 106, no. 2 (August 2011): 248-252. (Review)  Full Text  Link to Item
    • Gurbel, PA, Tantry, US, Bliden, KP, and Jeong, Y-H. "Immunity to thrombotic events is achievable if we stop the guessing game: is this the major hidden message from GRAVITAS?." Thromb Haemost 106, no. 2 (August 2011): 263-264.  Full Text  Link to Item
    • Gurbel, PA, and Tantry, US. "Clopidogrel response variability and the advent of personalised antiplatelet therapy. A bench to bedside journey." Thrombosis and Haemostasis 106, no. 2 (August 2011): 265-271. (Review)  Full Text
    • Bliden, KP, Tantry, US, Storey, RF, Jeong, Y-H, Gesheff, M, Wei, C, and Gurbel, PA. "The effect of ticagrelor versus clopidogrel on high on-treatment platelet reactivity: combined analysis of the ONSET/OFFSET and RESPOND studies." American Heart Journal 162, no. 1 (July 2011): 160-165.  Full Text
    • Jeong, Y-H, Bliden, KP, Tantry, US, Kim, I-S, Park, Y, and Gurbel, PA. "We need further studies for the development of "optimized antiplatelet therapy" based on ethnicity." Journal of the American College of Cardiology 58, no. 2 (July 2011): 198-null. (Letter)  Full Text
    • Jeong, Y-H, Bliden, KP, Tantry, US, and Gurbel, PA. "Do East Asians have different hypercoagulable states compared with Western population?." Am Heart J 162, no. 1 (July 2011): e19-e20. (Letter)  Full Text  Link to Item
    • Kandzari, DE, Mauri, L, Popma, JJ, Turco, MA, Gurbel, PA, Fitzgerald, PJ, and Leon, MB. "Late-term clinical outcomes with zotarolimus- and sirolimus-eluting stents. 5-year follow-up of the ENDEAVOR III (A Randomized Controlled Trial of the Medtronic Endeavor Drug [ABT-578] Eluting Coronary Stent System Versus the Cypher Sirolimus-Eluting Coronary Stent System in De Novo Native Coronary Artery Lesions)." Jacc. Cardiovascular Interventions 4, no. 5 (May 2011): 543-550.  Full Text
    • Bliden, KP, Tantry, US, DiChiara, J, and Gurbel, PA. "Further ex vivo evidence supporting higher aspirin dosing in patients with coronary artery disease and diabetes." Circ Cardiovasc Interv 4, no. 2 (April 1, 2011): 118-120.  Full Text  Link to Item
    • Tantry, US, Kereiakes, DJ, and Gurbel, PA. "Clopidogrel and proton pump inhibitors: influence of pharmacological interactions on clinical outcomes and mechanistic explanations." Jacc. Cardiovascular Interventions 4, no. 4 (April 2011): 365-380. (Review)  Full Text
    • Gurbel, PA, Shuldiner, AR, Bliden, KP, Ryan, K, Pakyz, RE, and Tantry, US. "The relation between CYP2C19 genotype and phenotype in stented patients on maintenance dual antiplatelet therapy." American Heart Journal 161, no. 3 (March 2011): 598-604.  Full Text
    • Gurbel, PA, and Tantry, US. "An initial experiment with personalized antiplatelet therapy: the GRAVITAS trial." Jama 305, no. 11 (March 2011): 1136-1137.  Full Text
    • Bergmeijer, TO, van Werkum, JW, Tantry, US, Gurbel, PA, and ten Berg, JM. "Platelet Function Testing in Clinical Practice - Experience and Views from Europe and the US." European Cardiology 7, no. 3 (January 1, 2011): 203-211.  Full Text
    • Gurbel, PA, and Tantry, US. "Antiplatelet therapy: Clopidogrel-PPI interaction, an ongoing controversy." Nature Reviews. Cardiology 8, no. 1 (January 2011): 7-8.  Full Text
    • Jeong, Y-H, Tantry, US, Bliden, KP, and Gurbel, PA. "Cilostazol to overcome high on-treatment platelet reactivity in korean patients treated with clopidogrel and calcium-channel blocker." Circulation Journal : Official Journal of the Japanese Circulation Society 75, no. 11 (January 2011): 2534-2536.  Full Text
    • Lau, WC, Welch, TD, Shields, T, Rubenfire, M, Tantry, US, and Gurbel, PA. "The effect of St John's Wort on the pharmacodynamic response of clopidogrel in hyporesponsive volunteers and patients: increased platelet inhibition by enhancement of CYP3A4 metabolic activity." Journal of Cardiovascular Pharmacology 57, no. 1 (January 2011): 86-93.  Full Text
    • Price, MJ, Tantry, US, and Gurbel, PA. "The influence of CYP2C19 polymorphisms on the pharmacokinetics, pharmacodynamics, and clinical effectiveness of P2Y(12) inhibitors." Reviews in Cardiovascular Medicine 12, no. 1 (January 2011): 1-12. (Review)  Full Text
    • Tantry, US, and Gurbel, PA. "Current options in oral antiplatelet strategies during percutaneous coronary interventions." Rev Cardiovasc Med 12 Suppl 1 (2011): S4-13. (Review)  Link to Item
    • Tantry, US, Bliden, KP, Wei, C, Storey, RF, Armstrong, M, Butler, K, and Gurbel, PA. "First analysis of the relation between CYP2C19 genotype and pharmacodynamics in patients treated with ticagrelor versus clopidogrel: the ONSET/OFFSET and RESPOND genotype studies." Circulation. Cardiovascular Genetics 3, no. 6 (December 2010): 556-566.  Full Text
    • Antonino, MJ, Coppolecchia, R, Mahla, E, Bliden, KP, Tantry, US, and Gurbel, PA. "Antiplatelet effects of aspirin with phytosterols: comparison with non-enteric coated aspirin alone." Thromb Res 126, no. 5 (November 2010): 384-385.  Full Text  Link to Item
    • Gurbel, PA, Kereiakes, D, and Tantry, US. "Elinogrel potassium: Receptor antagonist antiplatelet therapy." Drugs of the Future 35, no. 11 (November 1, 2010): 885-892. (Review)  Full Text
    • Gurbel, PA, Tantry, US, and Shuldiner, AR. "Letter by Gurbel et al regarding article, "Cytochrome 2C19*17 allelic variant, platelet aggregation, bleeding events, and stent thrombosis in clopidogrel-treated patients with coronary stent placement"." Circulation 122, no. 14 (October 2010): e478-null. (Letter)  Full Text
    • Gurbel, PA, and Tantry, US. "Acceptance of high platelet reactivity as a risk factor: now, what do we do about it?." Jacc. Cardiovascular Interventions 3, no. 10 (October 2010): 1008-1010.  Full Text
    • Mega, JL, Simon, T, Collet, J-P, Anderson, JL, Antman, EM, Bliden, K, Cannon, CP, Danchin, N, Giusti, B, Gurbel, P, Horne, BD, Hulot, J-S, Kastrati, A, Montalescot, G, Neumann, F-J, Shen, L, Sibbing, D, Steg, PG, Trenk, D, Wiviott, SD, and Sabatine, MS. "Reduced-function CYP2C19 genotype and risk of adverse clinical outcomes among patients treated with clopidogrel predominantly for PCI: a meta-analysis." Jama 304, no. 16 (October 2010): 1821-1830.  Full Text
    • Angiolillo, DJ, Saucedo, JF, Deraad, R, Frelinger, AL, Gurbel, PA, Costigan, TM, Jakubowski, JA, Ojeh, CK, Effron, MB, and SWAP Investigators, . "Increased platelet inhibition after switching from maintenance clopidogrel to prasugrel in patients with acute coronary syndromes: results of the SWAP (SWitching Anti Platelet) study." Journal of the American College of Cardiology 56, no. 13 (September 2010): 1017-1023.  Full Text
    • Bonello, L, Tantry, US, Marcucci, R, Blindt, R, Angiolillo, DJ, Becker, R, Bhatt, DL, Cattaneo, M, Collet, JP, Cuisset, T, Gachet, C, Montalescot, G, Jennings, LK, Kereiakes, D, Sibbing, D, Trenk, D, Van Werkum, JW, Paganelli, F, Price, MJ, Waksman, R, Gurbel, PA, and Working Group on High On-Treatment Platelet Reactivity, . "Consensus and future directions on the definition of high on-treatment platelet reactivity to adenosine diphosphate." Journal of the American College of Cardiology 56, no. 12 (September 2010): 919-933.  Full Text
    • Gurbel, PA, Kereiakes, DJ, and Tantry, US. "Ticagrelor for the treatment of arterial thrombosis." Expert Opinion on Pharmacotherapy 11, no. 13 (September 2010): 2251-2259. (Review)  Full Text
    • Mahla, E, Metzler, H, Tantry, US, and Gurbel, PA. "Controversies in oral antiplatelet therapy in patients undergoing aortocoronary bypass surgery." The Annals of Thoracic Surgery 90, no. 3 (September 2010): 1040-1051. (Review)  Full Text
    • Gurbel, PA, Bliden, KP, Navickas, IA, Mahla, E, Dichiara, J, Suarez, TA, Antonino, MJ, Tantry, US, and Cohen, E. "Adenosine diphosphate-induced platelet-fibrin clot strength: a new thrombelastographic indicator of long-term poststenting ischemic events." American Heart Journal 160, no. 2 (August 2010): 346-354.  Full Text
    • Gurbel, PA, Tantry, US, Shuldiner, AR, and Kereiakes, DJ. "Genotyping: one piece of the puzzle to personalize antiplatelet therapy." Journal of the American College of Cardiology 56, no. 2 (July 2010): 112-116.  Full Text
    • Storey, RF, Bliden, KP, Patil, SB, Karunakaran, A, Ecob, R, Butler, K, Teng, R, Wei, C, Tantry, US, Gurbel, PA, and ONSET/OFFSET Investigators, . "Incidence of dyspnea and assessment of cardiac and pulmonary function in patients with stable coronary artery disease receiving ticagrelor, clopidogrel, or placebo in the ONSET/OFFSET study." Journal of the American College of Cardiology 56, no. 3 (July 2010): 185-193.  Full Text
    • Hennekens, CH, Schneider, WR, Hebert, PR, Tantry, US, and Gurbel, PA. "Hypothesis formulation from subgroup analyses: nonadherence or nonsteroidal anti-inflammatory drug use explains the lack of clinical benefit of aspirin on first myocardial infarction attributed to "aspirin resistance"." American Heart Journal 159, no. 5 (May 2010): 744-748.  Full Text
    • Becker, RC, and Gurbel, PA. "Platelet P2Y12 receptor antagonist pharmacokinetics and pharmacodynamics: A foundation for distinguishing mechanisms of bleeding and anticipated risk for platelet-directed therapies." Thromb Haemost 103, no. 3 (March 2010): 535-544. (Review)  Full Text  Link to Item
    • Gurbel, P. "Aspirin - Scope and limitations." British Journal of Cardiology 17, no. SUPPL. 1 (March 1, 2010).
    • Gurbel, PA, Bliden, KP, Butler, K, Antonino, MJ, Wei, C, Teng, R, Rasmussen, L, Storey, RF, Nielsen, T, Eikelboom, JW, Sabe-Affaki, G, Husted, S, Kereiakes, DJ, Henderson, D, Patel, DV, and Tantry, US. "Response to ticagrelor in clopidogrel nonresponders and responders and effect of switching therapies: the RESPOND study." Circulation 121, no. 10 (March 2010): 1188-1199.  Full Text
    • Gurbel, PA, and Tantry, US. "Combination antithrombotic therapies." Circulation 121, no. 4 (February 2010): 569-583. (Review)  Full Text
    • Gurbel, PA, and Tantry, US. "Delivery of glycoprotein IIb/IIIa inhibitor therapy for percutaneous coronary intervention: why not take the intracoronary highway?." Circulation 121, no. 6 (February 2010): 739-741.  Full Text
    • Gurbel, PA, Bliden, KP, Antonino, MJ, Stephens, G, Gretler, DD, Jurek, MM, Pakyz, RE, Shuldiner, AR, Conley, PB, and Tantry, US. "The effect of elinogrel on high platelet reactivity during dual antiplatelet therapy and the relation to CYP2C19*2 genotype: first experience in patients." Journal of Thrombosis and Haemostasis : Jth 8, no. 1 (January 2010): 43-53.  Full Text
    • Gurbel, PA, Tantry, US, and Kereiakes, DJ. "Interaction between clopidogrel and proton-pump inhibitors and management strategies in patients with cardiovascular diseases." Drug, Healthcare and Patient Safety 2 (January 2010): 233-240.  Full Text
    • Tantry, US, Bliden, KP, Suarez, TA, Kreutz, RP, Dichiara, J, and Gurbel, PA. "Hypercoagulability, platelet function, inflammation and coronary artery disease acuity: results of the Thrombotic RIsk Progression (TRIP) study." Platelets 21, no. 5 (2010): 360-367.  Full Text  Link to Item
    • Gurbel, PA, Bliden, KP, Butler, K, Tantry, US, Gesheff, T, Wei, C, Teng, R, Antonino, MJ, Patil, SB, Karunakaran, A, Kereiakes, DJ, Parris, C, Purdy, D, Wilson, V, Ledley, GS, and Storey, RF. "Randomized double-blind assessment of the ONSET and OFFSET of the antiplatelet effects of ticagrelor versus clopidogrel in patients with stable coronary artery disease: the ONSET/OFFSET study." Circulation 120, no. 25 (December 2009): 2577-2585.  Full Text
    • Gurbel, PA, Tantry, US, and Shuldiner, AR. "The worry about clopidogrel "nonresponsiveness": identification and treatment in the post-percutaneous coronary intervention patient." Jacc. Cardiovascular Interventions 2, no. 11 (November 2009): 1102-1104.  Full Text
    • Singla, A, Antonino, MJ, Bliden, KP, Tantry, US, and Gurbel, PA. "The relation between platelet reactivity and glycemic control in diabetic patients with cardiovascular disease on maintenance aspirin and clopidogrel therapy." American Heart Journal 158, no. 5 (November 2009): 784.e1-784.e6.  Full Text
    • Tantry, US, and Gurbel, PA. "Platelet monitoring for PCI: is it really necessary?." Hamostaseologie 29, no. 4 (November 2009): 368-375. (Review)  Full Text
    • Tantry, US, Mahla, E, and Gurbel, PA. "Aspirin resistance." Prog Cardiovasc Dis 52, no. 2 (September 2009): 141-152. (Review)  Full Text  Link to Item
    • Gurbel, PA, Antonino, MJ, and Tantry, US. "Recent developments in clopidogrel pharmacology and their relation to clinical outcomes." Expert Opinion on Drug Metabolism & Toxicology 5, no. 8 (August 2009): 989-1004. (Review)  Full Text
    • Pinto Slottow, TL, Bonello, L, Gavini, R, Beauzile, P, Sushinsky, SJ, Scheinowitz, M, Kaneshige, K, Xue, Z, Torguson, R, Tantry, U, Pichard, AD, Satler, LF, Suddath, WO, Kent, K, Gurbel, P, and Waksman, R. "Prevalence of aspirin and clopidogrel resistance among patients with and without drug-eluting stent thrombosis." The American Journal of Cardiology 104, no. 4 (August 2009): 525-530.  Full Text
    • Shuldiner, AR, O'Connell, JR, Bliden, KP, Gandhi, A, Ryan, K, Horenstein, RB, Damcott, CM, Pakyz, R, Tantry, US, Gibson, Q, Pollin, TI, Post, W, Parsa, A, Mitchell, BD, Faraday, N, Herzog, W, and Gurbel, PA. "Association of cytochrome P450 2C19 genotype with the antiplatelet effect and clinical efficacy of clopidogrel therapy." Jama 302, no. 8 (August 2009): 849-857.  Full Text
    • Hoekstra, J, Cohen, M, Giugliano, R, Granger, CB, Gurbel, PA, Hollander, JE, Manoukian, SV, Saucedo, JF, and Pollack, CV. "Expert consensus on treatment strategies in non- ST-segment elevation acute coronary syndromes in patients undergoing percutaneous coronary intervention--an evidence-based review of clinical trial results and treatment guidelines from an emergency medicine perspective: report on a roundtable discussion." The American Journal of Emergency Medicine 27, no. 6 (July 2009): 720-728. (Review)  Full Text
    • Antonino, MJ, Mahla, E, Bliden, KP, Tantry, US, and Gurbel, PA. "Effect of long-term clopidogrel treatment on platelet function and inflammation in patients undergoing coronary arterial stenting." The American Journal of Cardiology 103, no. 11 (June 2009): 1546-1550.  Full Text
    • Gurbel, PA, and Tantry, US. "Antiplatelet resistance--fact or myth?." The American Heart Hospital Journal 7, no. 1 (June 2009): 50-57. (Review)
    • Gurbel, PA, Mahla, E, Antonino, MJ, and Tantry, US. "Response variability and the role of platelet function testing." The Journal of Invasive Cardiology 21, no. 4 (April 2009): 172-178. (Review)
    • Gilstad, JR, Gurbel, PA, and Andersen, RE. "Relationship between age and platelet activation in patients with stable and unstable angina." Arch Gerontol Geriatr 48, no. 2 (March 2009): 155-159.  Full Text  Link to Item
    • Gurbel, PA, Bliden, KP, Kreutz, RP, Dichiara, J, Antonino, MJ, and Tantry, US. "The link between heightened thrombogenicity and inflammation: pre-procedure characterization of the patient at high risk for recurrent events after stenting." Platelets 20, no. 2 (March 2009): 97-104.  Full Text  Link to Item
    • Hamed, MS, Gambert, S, Bliden, KP, Bailon, O, Singla, A, Antonino, MJ, Hamed, F, Tantry, US, and Gurbel, PA. "Dark chocolate effect on platelet activity, C-reactive protein and lipid profile: A pilot study Southern Medical Journal (2008) 101, (1203-1208))." Southern Medical Journal 102, no. 3 (March 1, 2009): 332-null.  Full Text
    • Lau, WC, and Gurbel, PA. "The drug-drug interaction between proton pump inhibitors and clopidogrel." Cmaj : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne 180, no. 7 (March 2009): 699-700.  Full Text
    • Mahla, E, Antonino, MJ, Tantry, US, and Gurbel, PA. "Point-of-care platelet function analysis ready for prime time?." Journal of the American College of Cardiology 53, no. 10 (March 2009): 857-859.  Full Text
    • Angiolillo, DJ, Bhatt, DL, Gurbel, PA, and Jennings, LK. "Advances in antiplatelet therapy: agents in clinical development." The American Journal of Cardiology 103, no. 3 Suppl (February 2009): 40A-51A. (Review)  Full Text
    • Gurbel, PA, Bliden, KP, Saucedo, JF, Suarez, TA, DiChiara, J, Antonino, MJ, Mahla, E, Singla, A, Herzog, WR, Bassi, AK, Hennebry, TA, Gesheff, TB, and Tantry, US. "Bivalirudin and clopidogrel with and without eptifibatide for elective stenting: effects on platelet function, thrombelastographic indexes, and their relation to periprocedural infarction results of the CLEAR PLATELETS-2 (Clopidogrel with Eptifibatide to Arrest the Reactivity of Platelets) study." Journal of the American College of Cardiology 53, no. 8 (February 2009): 648-657.  Full Text
    • Gurbel, PA, and Tantry, US. "Selecting optimal antiplatelet therapy based on platelet function monitoring in patients with coronary artery disease." Curr Treat Options Cardiovasc Med 11, no. 1 (February 2009): 22-32.  Link to Item
    • Gurbel, PA, Antonino, MJ, Bliden, KP, Dichiara, J, Suarez, TA, Singla, A, and Tantry, US. "Platelet reactivity to adenosine diphosphate and long-term ischemic event occurrence following percutaneous coronary intervention: a potential antiplatelet therapeutic target." Platelets 19, no. 8 (December 2008): 595-604.  Full Text
    • Gurbel, PA, and Tantry, US. "The rationale for and comparisons of different antiplatelet treatments in acute coronary syndrome." Journal of Interventional Cardiology 21 Suppl 1 (December 2008): S10-S17. (Review)  Full Text
    • Hamed, MS, Gambert, S, Bliden, KP, Bailon, O, Singla, A, Antonino, MJ, Hamed, F, Tantry, US, and Gurbel, PA. "Dark chocolate effect on platelet activity, C-reactive protein and lipid profile: a pilot study." Southern Medical Journal 101, no. 12 (December 2008): 1203-1208.  Full Text
    • Bliden, KP, Dichiara, J, Lawal, L, Singla, A, Antonino, MJ, Baker, BA, Bailey, WL, Tantry, US, and Gurbel, PA. "The association of cigarette smoking with enhanced platelet inhibition by clopidogrel." Journal of the American College of Cardiology 52, no. 7 (August 2008): 531-533.  Full Text
    • Cohen, M, Hoekstra, J, Giugliano, R, Granger, CB, Gurbel, PA, Hollander, JE, Manoukian, SV, Pollack, CV, and Saucedo, JF. "Treatment strategies in non-ST-elevation acute coronary syndromes in patients undergoing percutaneous coronary intervention: an evidence-based review of clinical trial results and treatment guidelines: report on a roundtable discussion." Journal of Interventional Cardiology 21, no. 4 (August 2008): 283-299. (Review)  Full Text
    • Gurbel, PA, Bliden, KP, Cohen, E, Navickas, IA, Singla, A, Antonino, MJ, Fissha, M, Kreutz, RP, Bassi, AK, and Tantry, US. "Race and sex differences in thrombogenicity: risk of ischemic events following coronary stenting." Blood Coagul Fibrinolysis 19, no. 4 (June 2008): 268-275.  Full Text  Link to Item
    • Dichiara, J, Bliden, KP, Tantry, US, Hamed, MS, Antonino, MJ, Suarez, TA, Bailon, O, Singla, A, and Gurbel, PA. "Response to comment on: dichiara et al. (2007) the effect of aspirin dosing on platelet function in diabetic and nondiabetic patients: an analysis from the aspirin-induced platelet effect (ASPECT) study: Diabetes 56:3014-3019, 2007." Diabetes 57, no. 5 (May 1, 2008). (Letter)  Full Text
    • Gurbel, PA, Antonino, MJ, and Tantry, US. "Antiplatelet treatment of cardiovascular disease: a translational research perspective." Polskie Archiwum Medycyny Wewnetrznej 118, no. 5 (May 2008): 289-297. (Review)
    • Kereiakes, DJ, and Gurbel, PA. "Peri-procedural platelet function and platelet inhibition in percutaneous coronary intervention." Jacc. Cardiovascular Interventions 1, no. 2 (April 2008): 111-121. (Review)  Full Text
    • Braunwald, E, Angiolillo, D, Bates, E, Berger, PB, Bhatt, D, Cannon, CP, Furman, MI, Gurbel, P, Michelson, AD, Peterson, E, and Wiviott, S. "Clinical considerations with the use of antiplatelet therapy in patients undergoing percutaneous coronary intervention." Clinical Cardiology 31, no. 3 Suppl 1 (March 2008): I28-I35. (Review)  Full Text
    • Braunwald, E, Angiolillo, D, Bates, E, Berger, PB, Bhatt, D, Cannon, CP, Furman, MI, Gurbel, P, Michelson, AD, Peterson, E, and Wiviott, S. "Antiplatelet strategies: evaluating their current role in the setting of acute coronary syndromes." Clinical Cardiology 31, no. 3 Suppl 1 (March 2008): I2-I9. (Review)  Full Text
    • Braunwald, E, Angiolillo, D, Bates, E, Berger, PB, Bhatt, D, Cannon, CP, Furman, MI, Gurbel, P, Michelson, AD, Peterson, E, and Wiviott, S. "Antiplatelet therapy and platelet function testing. Introduction." Clinical Cardiology 31, no. 3 Suppl 1 (March 2008): I1-null.  Full Text
    • Braunwald, E, Angiolillo, D, Bates, E, Berger, PB, Bhatt, D, Cannon, CP, Furman, MI, Gurbel, P, Michelson, AD, Peterson, E, and Wiviott, S. "The problem of persistent platelet activation in acute coronary syndromes and following percutaneous coronary intervention." Clinical Cardiology 31, no. 3 Suppl 1 (March 2008): I17-I20. (Review)  Full Text
    • Braunwald, E, Angiolillo, D, Bates, E, Berger, PB, Bhatt, D, Cannon, CP, Furman, MI, Gurbel, P, Michelson, AD, Peterson, E, and Wiviott, S. "Investigating the mechanisms of hyporesponse to antiplatelet approaches." Clinical Cardiology 31, no. 3 Suppl 1 (March 2008): I21-I27. (Review)  Full Text
    • Braunwald, E, Angiolillo, D, Bates, E, Berger, PB, Bhatt, D, Cannon, CP, Furman, MI, Gurbel, P, Michelson, AD, Peterson, E, and Wiviott, S. "Assessing the current role of platelet function testing." Clinical Cardiology 31, no. 3 Suppl 1 (March 2008): I10-I16. (Review)  Full Text
    • Gurbel, PA, and Tantry, US. "Prasugrel, a third generation thienopyridine and potent platelet inhibitor." Curr Opin Investig Drugs 9, no. 3 (March 2008): 324-336. (Review)  Link to Item
    • Gurbel, PA, Bliden, KP, Dichiara, J, Gesheff, T, Chaganti, SK, Etherington, A, Tantry, US, Newcomer, J, Weng, W, and Neerchal, NK. "Response to the letter regarding article, "Evaluation of dose-related effects of aspirin on platelet function: Results From the Aspirin-Induced Platelet Effect (ASPECT) study"." Circulation 117, no. 4 (January 29, 2008). (Letter)  Full Text
    • Gurbel, PA, Bilden, KP, and Tantry, US. "Diagnostics for aspirin resistance." Mol Diagn Ther 12, no. 1 (2008): 55-56.  Link to Item
    • Gurbel, PA, Kreutz, RP, Bliden, KP, DiChiara, J, and Tantry, US. "Biomarker analysis by fluorokine multianalyte profiling distinguishes patients requiring intervention from patients with long-term quiescent coronary artery disease: a potential approach to identify atherosclerotic disease progression." Am Heart J 155, no. 1 (January 2008): 56-61.  Full Text  Link to Item
    • Gurbel, PA, Lau, WC, and Tantry, US. "Omeprazole: a possible new candidate influencing the antiplatelet effect of clopidogrel." Journal of the American College of Cardiology 51, no. 3 (January 2008): 261-263.  Full Text
    • DiChiara, J, Bliden, KP, Tantry, US, Hamed, MS, Antonino, MJ, Suarez, TA, Bailon, O, Singla, A, and Gurbel, PA. "The effect of aspirin dosing on platelet function in diabetic and nondiabetic patients: an analysis from the aspirin-induced platelet effect (ASPECT) study." Diabetes 56, no. 12 (December 2007): 3014-3019.  Full Text  Link to Item
    • Kreutz, RP, Tantry, US, Bliden, KP, and Gurbel, PA. "Inflammatory changes during the 'common cold' are associated with platelet activation and increased reactivity of platelets to agonists." Blood Coagul Fibrinolysis 18, no. 8 (December 2007): 713-718.  Full Text  Link to Item
    • Gurbel, PA, Becker, RC, Mann, KG, Steinhubl, SR, and Michelson, AD. "Platelet function monitoring in patients with coronary artery disease." Journal of the American College of Cardiology 50, no. 19 (November 2007): 1822-1834. (Review)  Full Text
    • Gurbel, PA, Bliden, KP, Navickas, I, Cohen, E, and Tantry, US. "Post-coronary intervention recurrent ischemia in the presence of adequate platelet inhibition by dual antiplatelet therapy: what are we overlooking?." J Thromb Haemost 5, no. 11 (November 2007): 2300-2301. (Letter)  Full Text  Link to Item
    • Storey, RF, Husted, S, Harrington, RA, Heptinstall, S, Wilcox, RG, Peters, G, Wickens, M, Emanuelsson, H, Gurbel, P, Grande, P, and Cannon, CP. "Inhibition of platelet aggregation by AZD6140, a reversible oral P2Y12 receptor antagonist, compared with clopidogrel in patients with acute coronary syndromes." Journal of the American College of Cardiology 50, no. 19 (November 2007): 1852-1856.  Full Text
    • Gurbel, PA, DiChiara, J, and Tantry, US. "Antiplatelet Therapy After Implantation of Drug-Eluting Stents: Duration, Resistance, Alternatives, and Management of Surgical Patients." American Journal of Cardiology 100, no. 8 SUPPL. 2 (October 22, 2007).  Full Text
    • Dichiara, J, Bliden, KP, Tantry, US, Chaganti, SK, Kreutz, RP, Gesheff, TB, Kreutz, Y, and Gurbel, PA. "Platelet function measured by VerifyNow identifies generalized high platelet reactivity in aspirin treated patients." Platelets 18, no. 6 (September 2007): 414-423.  Full Text
    • Gurbel, PA, Bliden, KP, DiChiara, J, Newcomer, J, Weng, W, Neerchal, NK, Gesheff, T, Chaganti, SK, Etherington, A, and Tantry, US. "Evaluation of dose-related effects of aspirin on platelet function: results from the Aspirin-Induced Platelet Effect (ASPECT) study." Circulation 115, no. 25 (June 11, 2007): 3156-3164.  Full Text
    • Gurbel, P, Bliden, KP, and Tantry, U. "Evidence that pre-existent variability in platelet response to ADP accounts for 'clopidogrel resistance': a rebuttal." Journal of Thrombosis and Haemostasis : Jth 5, no. 5 (May 2007): 1087-1088. (Letter)  Full Text
    • Gurbel, PA, and Tantry, US. "[The role of clopidogrel in cardiovascular diseases]." Polskie Archiwum Medycyny Wewnetrznej 117, no. 5-6 (May 2007): 207-209.
    • Bliden, KP, DiChiara, J, Tantry, US, Bassi, AK, Chaganti, SK, and Gurbel, PA. "Increased risk in patients with high platelet aggregation receiving chronic clopidogrel therapy undergoing percutaneous coronary intervention: is the current antiplatelet therapy adequate?." Journal of the American College of Cardiology 49, no. 6 (February 2007): 657-666.  Full Text
    • Tantry, US, Bliden, KP, and Gurbel, PA. "AZD6140." Expert Opinion on Investigational Drugs 16, no. 2 (February 2007): 225-229. (Review)  Full Text
    • Gurbel, PA, Bliden, KP, Etherington, A, and Tantry, US. "Assessment of clopidogrel responsiveness: measurements of maximum platelet aggregation, final platelet aggregation and their correlation with vasodilator-stimulated phosphoprotein in resistant patients." Thrombosis Research 121, no. 1 (January 2007): 107-115.  Full Text
    • Gurbel, PA, Bliden, KP, Guyer, K, Aggarwal, N, and Tantry, US. "Delayed thrombin-induced platelet-fibrin clot generation by clopidogrel: a new dose-related effect demonstrated by thrombelastography in patients undergoing coronary artery stenting." Thrombosis Research 119, no. 5 (January 2007): 563-570.  Full Text
    • Gurbel, PA, and Kandzari, DE. "Stent thrombosis associated with first-generation drug-eluting stents: issues with antiplatelet therapy." Neth Heart J 15, no. 4 (2007): 148-150.  Link to Item
    • Gurbel, PA, and Tantry, US. "Stent thrombosis: role of compliance and nonresponsiveness to antiplatelet therapy." Rev Cardiovasc Med 8 Suppl 1 (2007): S19-S26. (Review)  Link to Item
    • Gurbel, PA, and Tantry, US. "Clopidogrel resistance?." Thrombosis Research 120, no. 3 (January 2007): 311-321. (Review)  Full Text
    • Gurbel, PA, Bliden, KP, and Tantry, US. "Effect of clopidogrel with and without eptifibatide on tumor necrosis factor-alpha and C-reactive protein release after elective stenting: results from the CLEAR PLATELETS 1b study." Journal of the American College of Cardiology 48, no. 11 (December 2006): 2186-2191.  Full Text
    • Kandzari, DE, Leon, MB, Popma, JJ, Fitzgerald, PJ, O'Shaughnessy, C, Ball, MW, Turco, M, Applegate, RJ, Gurbel, PA, Midei, MG, Badre, SS, Mauri, L, Thompson, KP, LeNarz, LA, Kuntz, RE, and ENDEAVOR III Investigators, . "Comparison of zotarolimus-eluting and sirolimus-eluting stents in patients with native coronary artery disease: a randomized controlled trial." Journal of the American College of Cardiology 48, no. 12 (December 2006): 2440-2447.  Full Text
    • Lau, WC, and Gurbel, PA. "Antiplatelet drug resistance and drug-drug interactions: Role of cytochrome P450 3A4." Pharmaceutical Research 23, no. 12 (December 2006): 2691-2708. (Review)  Full Text
    • Tantry, US, Bliden, KP, and Gurbel, PA. "Prasugrel." Expert Opinion on Investigational Drugs 15, no. 12 (December 2006): 1627-1633. (Review)  Full Text
    • Gurbel, PA, and Tantry, US. "Aspirin and clopidogrel resistance: consideration and management." Journal of Interventional Cardiology 19, no. 5 (October 2006): 439-448. (Review)  Full Text
    • Gurbel, PA, and Tantry, US. "Drug insight: Clopidogrel nonresponsiveness." Nature Clinical Practice. Cardiovascular Medicine 3, no. 7 (July 2006): 387-395. (Review)  Full Text
    • Tantry, US, Bliden, KP, and Gurbel, PA. "Reply." Journal of the American College of Cardiology 47, no. 12 (June 20, 2006): 2566-null. (Letter)  Full Text
    • Tantry, US, Etherington, A, Bliden, KP, and Gurbel, PA. "Antiplatelet therapy: current strategies and future trends." Future Cardiol 2, no. 3 (May 2006): 343-366.  Full Text  Link to Item
    • Bleske, BE, Nicklas, JM, Bard, RL, Brook, RD, Gurbel, PA, Bliden, KP, Rajagopalan, S, and Pitt, B. "Neutral effect on markers of heart failure, inflammation, endothelial activation and function, and vagal tone after high-dose HMG-CoA reductase inhibition in non-diabetic patients with non-ischemic cardiomyopathy and average low-density lipoprotein level." J Am Coll Cardiol 47, no. 2 (January 17, 2006): 338-341.  Full Text  Link to Item
    • Gurbel, PA, Lau, WC, Bliden, KP, and Tantry, US. "Clopidogrel resistance: implications for coronary stenting." Current Pharmaceutical Design 12, no. 10 (January 2006): 1261-1269. (Review)  Full Text
    • Gurbel, PA, and Singh, D. "Balloon angioplasty and repeat stenting may have similar long-term outcomes for people with in-stent restenosis: Commentary." Evidence Based Cardiovascular Medicine 10, no. 1 (January 1, 2006): 47-48.  Full Text
    • Gurbel, PA. "The relationship of platelet reactivity to the occurrence of post-stenting ischemic events: emergence of a new cardiovascular risk factor." Reviews in Cardiovascular Medicine 7 Suppl 4 (January 2006): S20-S28. (Review)
    • Wiviott, SD, Tantry, US, Gurbel, PA, American College of Cardiology, , and American Heart Association, . "Clinical applications of antiplatelet therapy." Reviews in Cardiovascular Medicine 7, no. 3 (January 2006): 130-146. (Review)
    • Tantry, US, Bliden, KP, and Gurbel, PA. "What is the best measure of thrombotic risks--pretreatment platelet aggregation, clopidogrel responsiveness, or posttreatment platelet aggregation?." Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions 66, no. 4 (December 2005): 597-598. (Letter)  Full Text
    • Gurbel, PA, Bliden, KP, Guyer, K, Cho, PW, Zaman, KA, Kreutz, RP, Bassi, AK, and Tantry, US. "Platelet reactivity in patients and recurrent events post-stenting: results of the PREPARE POST-STENTING Study." Journal of the American College of Cardiology 46, no. 10 (November 2005): 1820-1826.  Full Text
    • Gurbel, PA, Bliden, KP, Samara, W, Yoho, JA, Hayes, K, Fissha, MZ, and Tantry, US. "Clopidogrel effect on platelet reactivity in patients with stent thrombosis: results of the CREST Study." Journal of the American College of Cardiology 46, no. 10 (November 2005): 1827-1832.  Full Text
    • Tantry, US, Bliden, KP, and Gurbel, PA. "Overestimation of platelet aspirin resistance detection by thrombelastograph platelet mapping and validation by conventional aggregometry using arachidonic acid stimulation." J Am Coll Cardiol 46, no. 9 (November 1, 2005): 1705-1709.  Full Text  Link to Item
    • Tantry, US, Bliden, KP, and Gurbel, PA. "Resistance to antiplatelet drugs: current status and future research." Expert Opin Pharmacother 6, no. 12 (October 2005): 2027-2045. (Review)  Full Text  Link to Item
    • Kreutz, RP, Bliden, KP, Tantry, US, and Gurbel, PA. "Viral respiratory tract infections increase platelet reactivity and activation: an explanation for the higher rates of myocardial infarction and stroke during viral illness." J Thromb Haemost 3, no. 9 (September 2005): 2108-2109. (Letter)  Full Text  Link to Item
    • Michelson, AD, Cattaneo, M, Eikelboom, JW, Gurbel, P, Kottke-Marchant, K, Kunicki, TJ, Pulcinelli, FM, Cerletti, C, Rao, AK, Platelet Physiology Subcommittee of the Scientific and Standardization Committee of the International Society on Thrombosis and Haemostasis, , and Working Group on Aspirin Resistance, . "Aspirin resistance: position paper of the Working Group on Aspirin Resistance." Journal of Thrombosis and Haemostasis : Jth 3, no. 6 (June 2005): 1309-1311.  Full Text
    • Gurbel, PA, Bliden, KP, Hayes, KM, Yoho, JA, Herzog, WR, and Tantry, US. "The relation of dosing to clopidogrel responsiveness and the incidence of high post-treatment platelet aggregation in patients undergoing coronary stenting." Journal of the American College of Cardiology 45, no. 9 (May 2005): 1392-1396.  Full Text
    • Hermiller, JB, Raizner, A, Cannon, L, Gurbel, PA, Kutcher, MA, Wong, SC, Russell, ME, Ellis, SG, Mehran, R, Stone, GW, and TAXUS-IV Investigators, . "Outcomes with the polymer-based paclitaxel-eluting TAXUS stent in patients with diabetes mellitus: the TAXUS-IV trial." Journal of the American College of Cardiology 45, no. 8 (April 2005): 1172-1179.  Full Text
    • Gurbel, PA, Bliden, KP, Zaman, KA, Yoho, JA, Hayes, KM, and Tantry, US. "Clopidogrel loading with eptifibatide to arrest the reactivity of platelets: results of the Clopidogrel Loading With Eptifibatide to Arrest the Reactivity of Platelets (CLEAR PLATELETS) study." Circulation 111, no. 9 (March 2005): 1153-1159.  Full Text
    • Kreutz, RP, and Gurbel, PA. "Subacute stent thrombosis in an elderly man with clopidogrel resistance." Clinical Geriatrics 13, no. 3 (March 1, 2005): 37-40.
    • Poston, R, Gu, J, Brown, J, Gammie, J, White, C, Manchio, J, Pierson, RN, Griffith, BP, Gurbel, P, Tandry, U, and Gilbert, TB. "Hypercoagulability affecting early vein graft patency does not exist after off-pump coronary artery bypass." Journal of cardiothoracic and vascular anesthesia 19, no. 1 (February 2005): 11-18.  Full Text
    • Gelzer-Bell, R, and Gurbel, PA. "Diastolic heart failure in the older patient." Clinical Geriatrics 13, no. 1 (January 1, 2005): 18-21.
    • Gurbel, PA, Hayes, K, Bliden, KP, Yoho, J, and Tantry, US. "The platelet-related effects of tenecteplase versus alteplase versus reteplase." Blood Coagul Fibrinolysis 16, no. 1 (January 2005): 1-7.  Link to Item
    • Samara, WM, Bliden, KP, Tantry, US, and Gurbel, PA. "The difference between clopidogrel responsiveness and posttreatment platelet reactivity." Thrombosis Research 115, no. 1-2 (January 2005): 89-94.  Full Text
    • Gurbel, PA, Bliden, KP, Hayes, KM, and Tantry, U. "Platelet activation in myocardial ischemic syndromes." Expert Rev Cardiovasc Ther 2, no. 4 (July 2004): 535-545. (Review)  Full Text  Link to Item
    • Joynt, KE, Gattis, WA, Hasselblad, V, Fuzaylov, SY, Serebruany, VL, Gurbel, PA, Gaulden, LH, Felker, GM, Whellan, DJ, and O'Connor, CM. "Effect of angiotensin-converting enzyme inhibitors, beta blockers, statins, and aspirin on C-reactive protein levels in outpatients with heart failure." Am J Cardiol 93, no. 6 (March 15, 2004): 783-785.  Full Text  Link to Item
    • Gurbel, PA, Samara, WM, and Bliden, KP. "Failure of clopidogrel to reduce platelet reactivity and activation following standard dosing in elective stenting: implications for thrombotic events and restenosis." Platelets 15, no. 2 (March 2004): 95-99.  Full Text
    • Lau, WC, Gurbel, PA, Watkins, PB, Neer, CJ, Hopp, AS, Carville, DGM, Guyer, KE, Tait, AR, and Bates, ER. "Contribution of hepatic cytochrome P450 3A4 metabolic activity to the phenomenon of clopidogrel resistance." Circulation 109, no. 2 (January 5, 2004): 166-171.  Full Text
    • Gurbel, PA, and Bliden, KP. "A new method of representing drug-induced platelet inhibition: better description of time course, response variability, non-response, and heightened activity." Platelets 14, no. 7-8 (November 2003): 481-483.  Full Text
    • Gurbel, PA, and Bliden, KP. "Platelet activation after stenting with heparin-coated versus noncoated stents." Am Heart J 146, no. 4 (October 2003): E10-.  Full Text  Link to Item
    • Serebruany, VL, Malinin, AI, O'connor, CM, Gurbel, PA, and Substudy, ROCKET-IP. "Effects of roxifiban on platelet aggregation and major receptor expression in patients with coronary artery disease for the Roxifiban Oral Compound Kinetics Evaluation Trial-I (ROCKET-I Platelet Substudy)." American heart journal 146, no. 1 (July 2003): 91-98. (Academic Article)  Full Text
    • Gurbel, PA, Bliden, KP, Hiatt, BL, and O'Connor, CM. "Clopidogrel for coronary stenting: response variability, drug resistance, and the effect of pretreatment platelet reactivity." Circulation 107, no. 23 (June 9, 2003): 2908-2913.  Full Text
    • Gurbel, PA, Bliden, KP, and Hiatt, BL. "The early antiplatelet effects of clopidogrel loading for coronary stenting and the long-term stability of inhibition." Journal of Thrombosis and Haemostasis : Jth 1, no. 6 (June 2003): 1319-1321. (Letter)  Full Text
    • Gurbel, PA, and Bliden, KP. "Interpretation of platelet inhibition by clopidogrel and the effect of non-responders." Journal of Thrombosis and Haemostasis : Jth 1, no. 6 (June 2003): 1318-1319. (Letter)  Full Text
    • Gurbel, PA, and Bliden, KP. "Durability of platelet inhibition by clopidogrel." The American Journal of Cardiology 91, no. 9 (May 2003): 1123-1125.  Full Text
    • Serebruany, VL, Malinin, AI, Callahan, KP, Binbrek, A, Van De Werf, F, Alexander, JH, Granger, CB, Gurbel, PA, and Assessment of the Safety and Efficacy of a New Thrombolytic Agent platelet substudy, . "Effect of tenecteplase versus alteplase on platelets during the first 3 hours of treatment for acute myocardial infarction: the Assessment of the Safety and Efficacy of a New Thrombolytic Agent (ASSENT-2) platelet substudy." American Heart Journal 145, no. 4 (April 2003): 636-642.  Full Text
    • Gurbel, PA, Cummings, CC, Bell, CR, Alford, AB, Meister, AF, Serebruany, VL, and Plavix Reduction Of New Thrombus Occurrence (PRONTO) trial, . "Onset and extent of platelet inhibition by clopidogrel loading in patients undergoing elective coronary stenting: the Plavix Reduction Of New Thrombus Occurrence (PRONTO) trial." American Heart Journal 145, no. 2 (February 2003): 239-247.  Full Text
    • Samara, WM, and Gurbel, PA. "The role of platelet receptors and adhesion molecules in coronary artery disease." Coronary Artery Disease 14, no. 1 (February 2003): 65-79. (Review)  Full Text
    • Gurbel, PA, and Bliden, KP. "The stratification of platelet reactivity and activation in patients with stable coronary artery disease on aspirin therapy." Thromb Res 112, no. 1-2 (2003): 9-12.  Full Text  Link to Item
    • Gurbel, PA, Austin, B, Cho, PW, and Sequeira, AJ. "Correction of a saphenous vein graft to coronary vein anastamosis by selective retrograde coil-induced occlusion to arterialize the native vein." Catheter Cardiovasc Interv 57, no. 4 (December 2002): 541-544.  Full Text  Link to Item
    • Gurbel, PA, Galbut, B, Bliden, KP, Bahr, RD, Roe, MT, Serebruany, VL, Gibler, WB, Christenson, RH, Ohman, EM, and EARLY Platelet Substudy, . "Effect of eptifibatide for acute coronary syndromes: rapid versus late administration--therapeutic yield on platelets (The EARLY Platelet Substudy)." Journal of Thrombosis and Thrombolysis 14, no. 3 (December 2002): 213-219.  Full Text
    • Serebruany, VL, McKenzie, ME, Meister, AF, Fuzaylov, SY, Gurbel, PA, Atar, D, Gattis, WA, and O'Connor, CM. "Failure of platelet parameters and biomarkers to correlate platelet function to severity and etiology of heart failure in patients enrolled in the EPCOT trial: With special reference to the hemodyne® hemostatic analyzer." Pathophysiology of Haemostasis and Thrombosis 32, no. 1 (December 1, 2002): 8-15.  Full Text
    • Faxon, DP, Gibbons, RJ, Chronos, NAF, Gurbel, PA, Sheehan, F, and HALT-MI Investigators, . "The effect of blockade of the CD11/CD18 integrin receptor on infarct size in patients with acute myocardial infarction treated with direct angioplasty: the results of the HALT-MI study." Journal of the American College of Cardiology 40, no. 7 (October 2002): 1199-1204.  Full Text
    • Gurbel, PA, Callahan, KP, Malinin, AI, Serebruany, VL, and Gillis, J. "Could stent design affect platelet activation? Results of the Platelet Activation in STenting (PAST) Study." J Invasive Cardiol 14, no. 10 (October 2002): 584-589.  Link to Item
    • Bahr, RD, Gurbel, PA, Malinin, AI, Wentz, C, Christenson, RH, Roe, MT, Gibler, WB, Kitt, MM, Ohman, EM, and Serebruany, VL. "Relation of platelet activation and myocardial ischemia biomarkers dependent on type of chest pain (abrupt onset versus intermittent) in patients with angina pectoris or non-Q-wave acute myocardial infarction." Am J Cardiol 90, no. 3 (August 1, 2002): 310-312.  Link to Item
    • Gurbel, PA, Malinin, AI, Callahan, KP, Serebruany, VL, and O'Connor, CM. "Effect of loading with clopidogrel at the time of coronary stenting on platelet aggregation and glycoprotein IIb/IIIa expression and platelet-leukocyte aggregate formation." The American Journal of Cardiology 90, no. 3 (August 2002): 312-315.  Full Text
    • Gurbel, PA, Gattis, WA, Fuzaylov, SF, Gaulden, L, Hasselblad, V, Serebruany, VL, and O'Connor, CM. "Evaluation of platelets in heart failure: is platelet activity related to etiology, functional class, or clinical outcomes?." American heart journal 143, no. 6 (June 2002): 1068-1075. (Academic Article)
    • Gurbel, PA, and Serebruany, VL. "Adhesion molecules, platelet activation, and cardiovascular risk." Am Heart J 143, no. 2 (February 2002): 196-198.  Link to Item
    • Serebruanya, VL, McKenzie, ME, Meistera, AF, Fuzaylov, SY, Gurbel, PA, Atar, D, Gattis, WA, and O'Connor, CM. "Whole blood impedance aggregometry for the assessment of platelet function in patients with congestive heart failure (EPCOT trial)." European Journal of Heart Failure 4, no. 4 (2002): 461-467.  Full Text
    • Callahan, KP, Malinin, AI, Gurbel, PA, Alexander, JH, Granger, CB, Atar, D, and Serebruany, VL. "Platelets and thrombolysis: Cooperation or contrariety?." Heartdrug 1, no. 5 (December 1, 2001): 281-290. (Review)  Full Text
    • Serebruany, VL, Malinin, AI, Callahan, KP, Gurbel, PA, and Steinhubl, SR. "Statins do not affect platelet inhibition with clopidogrel during coronary stenting." Atherosclerosis 159, no. 1 (November 2001): 239-241. (Letter)  Full Text
    • Serebruany, VL, Cummings, CC, Malinin, AI, Steinhubl, SR, and Gurbel, PA. "Uniform platelet activation exists before coronary stent implantation despite aspirin therapy." Am Heart J 142, no. 4 (October 2001): 611-616.  Full Text  Link to Item
    • Serebruany, VL, O'Connor, CM, and Gurbel, PA. "Effect of selective serotonin reuptake inhibitors on platelets in patients with coronary artery disease." The American journal of cardiology 87, no. 12 (June 2001): 1398-1400. (Academic Article)
    • Serebruany, VL, Gurbel, PA, and O'Connor, CM. "Platelet inhibition by sertraline and N-desmethylsertraline: a possible missing link between depression, coronary events, and mortality benefits of selective serotonin reuptake inhibitors." Pharmacological Research 43, no. 5 (May 2001): 453-462.  Full Text
    • Serebruany, VL, Levine, DJ, Nair, GV, Meister, AF, and Gurbel, PA. "Usefulness of combining necrosis and platelet markers in triaging patients presenting with chest pain to the emergency department." J Thromb Thrombolysis 11, no. 2 (April 2001): 155-162.  Link to Item
    • Serebruany, VL, Malinin, AI, Bell, CR, and Gurbel, PA. "Heparin prevents xylum clot signature analyser to detect platelet inhibition with clopidogrel during coronary stenting [2]." Thrombosis Research 102, no. 1 (April 1, 2001): 95-97. (Letter)  Full Text
    • Gurbel, PA, O'Connor, CM, Dalesandro, MR, and Serebruany, VL. "Relation of soluble and platelet P-selectin to early outcome in patients with acute myocardial infarction after thrombolytic therapy." The American journal of cardiology 87, no. 6 (March 2001): 774-7, A7. (Academic Article)
    • Serebruany, VL, Alford, AB, Meister, AF, Fuzaylov, SY, Gattis, WA, Gurbel, PA, and O'Connor, CM. "Clinical utility of the platelet function analyzer (PFA-100) for the assessment of the platelet status in patients with congestive heart failure (EPCOT trial)." Thrombosis research 101, no. 6 (March 2001): 427-433. (Academic Article)
    • Ishizuka, Y, Minokawa, T, and Amemiya, S. "Micromere descendants at the blastula stage are involved in normal archenteron formation in sea urchin embryos." Development genes and evolution 211, no. 2 (February 2001): 83-88.  Full Text
    • Cummings, CC, McKenzie, ME, Horowitz, ED, Oshrine, BR, Callahan, KP, Gurbel, PA, and Serebruany, VL. "Platelet function and total length of intracoronary stents: is there a correlation?." Thromb Res 101, no. 2 (January 15, 2001): 105-107. (Letter)  Link to Item
    • Callahan, KP, Malinin, AI, Gurbel, PA, Alexander, JH, Granger, CB, and Serebruany, VL. "Platelet function and fibrinolytic agents: two sides of a coin?." Cardiology 95, no. 2 (January 2001): 55-60.  Full Text
    • McKenzie, ME, and Gurbel, PA. "The potential of monoclonal antibodies to reduce reperfusion injury in myocardial infarction." Biodrugs : Clinical Immunotherapeutics, Biopharmaceuticals and Gene Therapy 15, no. 6 (January 2001): 395-404.  Full Text
    • Semaan, HB, Gurbel, PA, Anderson, JL, Muhlestein, JB, Carlquist, JF, Horne, BD, and Serebruany, VL. "The effect of chronic azithromycin therapy on soluble endothelium-derived adhesion molecules in patients with coronary artery disease." J Cardiovasc Pharmacol 36, no. 4 (October 2000): 533-537.  Link to Item
    • Serebruany, VL, Atar, D, Murugesan, SR, Jerome, S, Semaan, H, and Gurbel, PA. "Effect of coronary thrombolysis on the plasma concentration of osteonectin (SPARC, BM40) in patients with acute myocardial infarction." J Thromb Thrombolysis 10, no. 2 (October 2000): 197-202.  Link to Item
    • Pothula, A, Serebruany, VL, Gurbel, PA, McKenzie, ME, and Atar, D. "Pathophysiology and therapeutic modification of thrombin generation in patients with coronary artery disease." Eur J Pharmacol 402, no. 1-2 (August 18, 2000): 1-10. (Review)  Link to Item
    • Davis, CJ, Gurbel, PA, Gattis, WA, Fuzaylov, SY, Nair, GV, O'Connor, CM, and Serebruany, VL. "Hemostatic abnormalities in patients with congestive heart failure: diagnostic significance and clinical challenge." International journal of cardiology 75, no. 1 (August 2000): 15-21. (Academic Article)
    • Gurbel, PA, Kereiakes, DJ, and Serebruany, VL. "Soluble P-selectin is not a surrogate marker for platelet P-selectin: evidence from a multicenter chest pain study group." J Thromb Thrombolysis 10, no. 1 (August 2000): 15-22.  Link to Item
    • Gurbel, PA, McKenzie, ME, and Serebruany, VL. "Initial platelet activity may predict efficacy after chronic oral glycoprotein IIb/IIIa blockade: should we still consider uniform treatment regimens?." Thromb Res 99, no. 1 (July 1, 2000): 105-107. (Letter)  Link to Item
    • Serebruany, VL, Lowry, DR, Fuzailov, SY, Levine, DJ, O'Connor, CM, and Gurbel, PA. "Moderate alcohol consumption is associated with decreased platelet activity in patients presenting with acute myocardial infarction." Journal of thrombosis and thrombolysis 9, no. 3 (April 2000): 229-234. (Academic Article)
    • Gurbel, PA, Kereiakes, DJ, Dalesandro, MR, Bahr, RD, O'Connor, CM, and Serebruany, VL. "Role of soluble and platelet-bound P-selectin in discriminating cardiac from noncardiac chest pain at presentation in the emergency department." American heart journal 139, no. 2 Pt 1 (February 2000): 320-328. (Academic Article)
    • Serebruany, VL, McKenzie, ME, Levin, DJ, and Gurbel, PA. "Monitoring platelet inhibition during chronic oral platelet glycoprotein IIb/IIIa blockade: are we missing something?." Thromb Haemost 83, no. 2 (February 2000): 356-357. (Letter)  Link to Item
    • GURBEL, P. "Oral platelet IIb/IIIa inhibitors : from attractive theory to clinical failures." J Thromb Thrombolysis 10 (2000): 217-220.  Full Text
    • Gurbel, PA, Kereiakes, DJ, Atar, D, and Serebruany, VL. "Baseline platelet aggregation and major receptor expression predict subsequent activity following thrombolysis for acute myocardial infarction." Scand Cardiovasc J 34, no. 1 (2000): 53-58.  Link to Item
    • Nair, GV, Gurbel, PA, Fuzaylov, SY, Davis, CJ, Ohman, EM, Bahr, RD, Christensen, RH, and Serebruany, VL. "Combining necrosis and platelet markers for perfecting myocardial infarction rule out: how close are we?." Cardiology 93, no. 1-2 (2000): 50-55. (Review)  Full Text  Link to Item
    • O'Connor, CM, Gurbel, PA, and Serebruany, VL. "Depression and ischemic heart disease." American Heart Journal 140, no. 4 SUPPL. (January 1, 2000).  Full Text
    • Semaan, HB, Gurbel, PA, Anderson, JL, Muhlestein, JB, Carlquist, JF, Horne, BD, and Serebruany, VL. "Soluble VCAM-1 and E-selectin, but not ICAM-1 discriminate endothelial injury in patients with documented coronary artery disease." Cardiology 93, no. 1-2 (2000): 7-10.  Full Text  Link to Item
    • Serebruany, VL, Kereiakes, DJ, Dalesandro, MR, and Gurbel, PA. "The flow cytometer model markedly affects measurement of ex vivo whole blood platelet-bound P-selectin expression in patients with chest pain: are we comparing apples with oranges." Thromb Res 96, no. 1 (October 1, 1999): 51-56.  Link to Item
    • Serebruany, VL, Yurovsky, VV, and Gurbel, PA. "Mild myocardial stunning affects platelet aggregation and certain hemostatic factors in swine." Clin Appl Thromb Hemost 5, no. 4 (October 1999): 236-242.  Link to Item
    • Murugesan, SR, Gurbel, PA, and Serebruany, VL. "Storing paraformaldehyde-fixed whole blood patient samples after chronic platelet glycoprotein IIb/IIIa blockade: core laboratory considerations." Thromb Res 95, no. 4 (August 15, 1999): 201-203. (Letter)  Link to Item
    • Gurbel, PA, O'Connor, CM, Cummings, CC, and Serebruany, VL. "Clopidogrel: the future choice for preventing platelet activation during coronary stenting?." Pharmacological Research 40, no. 2 (August 1999): 107-111. (Review)  Full Text
    • Nair, GV, Gurbel, PA, O'Connor, CM, Gattis, WA, Murugesan, SR, and Serebruany, VL. "Depression, coronary events, platelet inhibition, and serotonin reuptake inhibitors." The American journal of cardiology 84, no. 3 (August 1999): 321-3, A8. (Academic Article)
    • Serebruany, VL, Murugesan, SR, Pothula, A, Atar, D, Lowry, DR, O'Connor, CM, and Gurbel, PA. "Increased soluble platelet/endothelial cellular adhesion molecule-1 and osteonectin levels in patients with severe congestive heart failure. Independence of disease etiology, and antecedent aspirin therapy." European Journal of Heart Failure 1, no. 3 (August 1999): 243-249.  Full Text
    • Gurbel, PA, Murugesan, SR, Lowry, DR, and Serebruany, VL. "Plasma thromboxane and prostacyclin are linear related and increased in patients presenting with acute myocardial infarction." Prostaglandins Leukot Essent Fatty Acids 61, no. 1 (July 1999): 7-11.  Link to Item
    • O'Connor, CM, Gurbel, PA, and Serebruany, VL. "Usefulness of soluble and surface-bound P-selectin in detecting heightened platelet activity in patients with congestive heart failure." The American journal of cardiology 83, no. 9 (May 1999): 1345-1349. (Academic Article)
    • Serebruany, VL, and Gurbel, PA. "The relations of major platelet receptor expression during myocardial infarction. Monitoring efficacy of GPIIb/IIIa inhibitors by measuring P-selectin?." Thromb Haemost 81, no. 2 (February 1999): 314-316. (Letter)  Link to Item
    • Serebruany, VL, and Gurbel, PA. "Assessment of platelet activity by measuring platelet-derived substances in plasma from patients with acute myocardial infarction: surprising lessons from the GUSTO-III Platelet Study." Thromb Res 93, no. 3 (February 1, 1999): 149-150. (Letter)  Link to Item
    • McKenzie, ME, Gurbel, PA, Levine, DJ, and Serebruany, VL. "Clinical utility of available methods for determining platelet function." Cardiology 92, no. 4 (1999): 240-247. (Review)  Full Text  Link to Item
    • McKenzie, ME, Pothula, A, Gurbel, PA, Fuzaylov, SY, O'Connor, CM, Gattis, WA, and Serebruany, VL. "Failure of thrombin generation markers to triage patients presenting with chest pain." Cardiology 92, no. 1 (1999): 53-58. (Academic Article)
    • Serebruany, VL, Murugesan, SR, Pothula, A, Semaan, H, and Gurbel, PA. "Soluble PECAM-1, but not P-selectin, nor osteonectin identify acute myocardial infarction in patients presenting with chest pain." Cardiology 91, no. 1 (1999): 50-55.  Full Text  Link to Item
    • Serebruany, VL, Yurovsky, VV, and Gurbel, PA. "Effects of a novel Mac-1 inhibitor, NPC 15669, on hemostatic parameters during preconditioned myocardial infarction." Life Sci 65, no. 14 (1999): 1503-1513.  Link to Item
    • Serebruany, VL, and Gurbel, PA. "Effect of thrombolytic therapy on platelet expression and plasma concentration of PECAM-1 (CD31) in patients with acute myocardial infarction." Arterioscler Thromb Vasc Biol 19, no. 1 (January 1999): 153-158.  Link to Item
    • Gurbel, PA, Serebruany, V, Mergner, WJ, and Kolodgie, F. "Chapter 4 Myocardial cell injury during ischemia and reflow." Principles of Medical Biology 13, no. C (December 1, 1998): 127-166.  Full Text
    • Gurbel, PA, Dalesandro, MR, and Serebruany, VL. "Reteplase but not alteplase affects early soluble PECAM-1 and P-selectin release in patients with acute myocardial infarction." Thromb Haemost 80, no. 4 (October 1998): 725-. (Letter)  Link to Item
    • Serebruany, VL, Gurbel, PA, Murugesan, SR, Lowry, DR, Sturm, E, and Svetlov, SI. "Depressed plasma platelet-activating factor acetylhydrolase in patients presenting with acute myocardial infarction." Cardiology 90, no. 2 (October 1998): 127-130.  Full Text  Link to Item
    • Serebruany, VL, Gurbel, PA, Shustov, AR, Ohman, EM, and Topol, EJ. "Heterogeneity of platelet aggregation and major surface receptor expression in patients with acute myocardial infarction." Am Heart J 136, no. 3 (September 1998): 398-405.  Link to Item
    • Serebruany, VL, Gurbel, PA, and Investigators, GUSTOIII. "Depressed platelet status in an elderly patient with hemorrhagic stroke after thrombolysis for acute myocardial infarction - Response." STROKE 29, no. 9 (September 1998): 2002-2003.  Link to Item
    • Serebruany, VL, Schlossberg, ML, Edenbaum, LR, Herzog, WR, and Gurbel, PA. "Serial changes of soluble endothelin-1 levels during myocardial ischaemia-reperfusion. Effects of magnesium, diltiazem and a novel MAC-1 inhibitor." Pharmacol Res 38, no. 3 (September 1998): 165-172.  Full Text  Link to Item
    • Serebruany, VL, Bahr, RD, O'Connor, CM, Lowry, DR, and Gurbel, PA. "Antecedent aspirin therapy inhibits baseline platelet activity in patients presenting with acute myocardial infarction." Cardiology 90, no. 1 (July 1, 1998): 37-42.  Full Text
    • Gurbel, PA, Serebruany, VL, Shustov, AR, Bahr, RD, Carpo, C, Ohman, EM, and Topol, EJ. "Effects of reteplase and alteplase on platelet aggregation and major receptor expression during the first 24 hours of acute myocardial infarction treatment." Journal of the American College of Cardiology 31, no. 7 (June 1, 1998): 1466-1473.  Full Text
    • Serebruany, VL, Solomon, SR, Herzog, WR, and Gurbel, PA. "Plasma fibronectin during myocardial ischemia-reperfusion: effects of magnesium, diltiazem, and a novel Mac-1 inhibitor." Am J Hematol 57, no. 4 (April 1998): 309-314.  Link to Item
    • Gurbel, PA, and Serebruany, VL. "Soluble vascular cell adhesion molecule-1 and E-selectin in patients with acute myocardial infarction treated with thrombolytic agents." Am J Cardiol 81, no. 6 (March 15, 1998): 772-775.  Link to Item
    • Gurbel, PA, Serebruany, VL, Shustov, AR, Dalesandro, M, Gumbs, CI, Grablutz, LB, Bahr, RD, Ohman, EM, and Topol, EJ. "Increased baseline levels of platelet P-selectin, and platelet-endothelial cell adhesion molecule-1 in patients with acute myocardial infarction as predictors of unsuccessful thrombolysis." Coron Artery Dis 9, no. 7 (1998): 451-456.  Link to Item
    • Serebruany, VL, Atar, D, Dalesandro, MR, O'Connor, CM, and Gurbel, PA. "Changes in hemostasis after parenteral magnesium in myocardial ischemia-reperfusion: From animal studies to clinical trials." Magnesium Research 11, no. 2 (1998): 133-140.
    • Serebruany, VL, Gurbel, PA, Shustov, AR, Dalesandro, MR, Gumbs, CI, Grabletz, LB, Bahr, RD, Ohman, EM, and Topol, EJ. "Depressed platelet status in an elderly patient with hemorrhagic stroke after thrombolysis for acute myocardial infarction. GUSTO-III Investigators." Stroke 29, no. 1 (January 1998): 235-238.  Full Text
    • Serebruany, VL, Ordonez, JV, Yurovsky, VV, and Gurbel, PA. "Crossreactivity of Human versus Swine Platelet Surface Antigens Is Similar for Glycoproteins Ib and IIIa, but Not for the Glycoprotein IIb/IIIa Complex." J Thromb Thrombolysis 5, no. 1 (1998): 37-41.  Link to Item
    • Serebruany, VL, Solomon, SR, Shustov, AR, Herzog, WR, and Gurbel, PA. "Survival in Acute Myocardial Infarction Induced by Coronary Ligation: Prognostic Relevance of Certain Hemostatic Factors During the Occlusion Phase." J Thromb Thrombolysis 5, no. 1 (1998): 29-35.  Full Text  Link to Item
    • Gurbel, PA, and Serebruany, VL. "Myths and realities of P-selectin plasma levels in patients with acute myocardial infarction." Thromb Res 88, no. 3 (November 1, 1997): 343-344. (Letter)  Link to Item
    • Serebruany, VL, Schlossberg, ML, Edenbaum, LR, Herzog, WR, and Gurbel, PA. "Effects of intracoronary diltiazem on certain hemostatic parameters during acute myocardial infarction in swine." Int J Cardiol 61, no. 1 (August 29, 1997): 21-29.  Link to Item
    • Serebruany, VL, Herzog, WR, Schlossberg, ML, and Gurbel, PA. "Bolus magnesium infusion in humans is associated with predominantly unfavourable changes in platelet aggregation and certain haemostatic factors." Pharmacol Res 36, no. 1 (July 1997): 17-22.  Full Text  Link to Item
    • Gurbel, PA, Anderson, RD, Peels, HO, vanBoven, AJ, and denHeijer, P. "Coronary artery angioplasty with a helical autoperfusion balloon catheter." CATHETERIZATION AND CARDIOVASCULAR DIAGNOSIS 40, no. 2 (February 1997): 179-185.  Full Text  Link to Item
    • Serebruany, VL, Herzog, WR, and Gurbel, PA. "Serial changes of the plasma prostanoids during myocardial ischemia-reperfusion in swine. Effects of magnesium, diltiazem, and a novel Mac-1 inhibitor." Prostaglandins Leukot Essent Fatty Acids 56, no. 2 (February 1997): 135-142.  Link to Item
    • Gurbel, PA, Criado, FJ, Curnutte, EA, Patten, P, and Secada-Lovio, J. "Percutaneous revascularization of an extensively diseased saphenous vein bypass graft with a saphenous vein-covered Palmaz stent." Cathet Cardiovasc Diagn 40, no. 1 (January 1997): 75-78. (Review)  Link to Item
    • Serebruany, VL, Gurbel, PA, Ordoñez, JV, Herzog, WR, Rohde, M, Mortensen, SA, and Folkers, K. "Could coenzyme Q10 affect hemostasis by inhibiting platelet vitronectin (CD51/CD61) receptor?." Mol Aspects Med 18 Suppl (1997): S189-S194.  Link to Item
    • Serebruany, VL, Ordonez, JV, Herzog, WR, Rohde, M, Mortensen, SA, Folkers, K, and Gurbel, PA. "Dietary coenzyme Q10 supplementation alters platelet size and inhibits human vitronectin (CD51/CD61) receptor expression." J Cardiovasc Pharmacol 29, no. 1 (January 1997): 16-22.  Link to Item
    • Serebruany, VL, Herzog, WR, Schlossberg, ML, Edenbaum, LR, and Gurbel, PA. "Hemostatic changes after early versus late intracoronary magnesium during acute myocardial infarction in swine." J Cardiovasc Pharmacol 28, no. 6 (December 1996): 817-823.  Link to Item
    • Serebruany, VL, Herzog, WR, and Gurbel, PA. "Mild myocardial stunning affects platelet aggregation and hemostasis in swine." Faseb Journal 10, no. 3 (December 1, 1996).
    • Serebruany, VL, Herzog, WR, Edenbaum, LR, Shustov, AR, and Gurbel, PA. "Changes in the haemostatic profile during magnesium deficiency in swine." Magnes Res 9, no. 3 (October 1996): 155-163.  Link to Item
    • Serebruany, VL, Schlossberg, ML, Edenbaum, LR, Herzog, WR, and Gurbel, PA. "Intracoronary magnesium and diltiazem affect to a similar extent certain hemostatic factors during acute myocardial infarction in swine." Pharmacology 53, no. 4 (October 1996): 224-233.  Full Text  Link to Item
    • Serebruany, VL, Herzog, WR, and Gurbel, PA. "Serial changes of natural antithrombotics during myocardial ischemia-reperfusion in swine. Effects of magnesium, diltiazem, and a novel Mac-1 inhibitor." Blood Coagul Fibrinolysis 7, no. 6 (September 1996): 632-640.  Link to Item
    • Gurbel, PA, Serebruany, VL, Komiathy, SF, Collins, ME, Bittar, GD, Schlossberg, ML, and Mergner, W. "Pretreatment with an inhibitor of mac-1 alters regional and systemic platelet function during ischemia-reperfusion in swine." Pharmacology 53, no. 2 (August 1996): 79-86.  Full Text  Link to Item
    • Serebruany, VL, Herzog, WR, Atamas, SP, Gurbel, PA, Rohde, M, Mortensen, SA, and Folkers, K. "Hemostatic changes after dietary coenzyme Q10 supplementation in swine." J Cardiovasc Pharmacol 28, no. 2 (August 1996): 175-181.  Link to Item
    • Serebruany, VL, Solomon, SR, Edenbaum, LR, Herzog, WR, and Gurbel, PA. "Mac-1 inhibitor affects certain hemostatic parameters during myocardial stunning in swine." Pharmacology 53, no. 2 (August 1996): 87-97.  Full Text  Link to Item
    • Anderson, RD, and Gurbel, PA. "The effect of intra-aortic balloon counterpulsation on coronary blood flow velocity distal to coronary artery stenoses." Cardiology 87, no. 4 (July 1996): 306-312.  Full Text  Link to Item
    • Gurbel, PA, Navetta, FI, Bates, ER, Muller, DW, Tenaglia, AN, Miller, MJ, Muhlstein, B, Hermiller, JB, Davidson, CJ, Aguirre, FV, Beauman, GJ, Berdan, LG, Leimberger, JD, Bovill, EG, Christenson, RH, and Ohman, EM. "Lesion-directed administration of alteplase with intracoronary heparin in patients with unstable angina and coronary thrombus undergoing angioplasty." Catheterization and Cardiovascular Diagnosis 37, no. 4 (April 1996): 382-391.  Full Text
    • Gurbel, PA. ""Functional characteristics of a new perfusion balloon: comparison with the Flowtrack 40 in a closed chest swine"." Cathet Cardiovasc Diagn 36, no. 4 (December 1995): 377-378. (Letter)  Link to Item
    • Gurbel, PA, and O'Connor, CM. "Zofenopril after anterior myocardial infarction." The New England journal of medicine 332, no. 25 (June 1995): 1715-. (Academic Article)  Full Text
    • Benitez, RM, Gurbel, PA, Chong, H, and Rajasingh, MC. "Penetrating atherosclerotic ulcer of the aortic arch resulting in extensive and fatal dissection." Am Heart J 129, no. 4 (April 1995): 821-823.  Link to Item
    • Pimentel, CX, Schreiter, SW, and Gurbel, PA. "The use of the Tracker catheter as a guidewire support device in angioplasty of angulated and tortuous circumflex coronary arteries." J Invasive Cardiol 7, no. 3 (April 1995): 66-71.  Link to Item
    • Gurbel, PA, Serebruany, VL, Komjathy, SF, Collins, ME, Sane, DC, Scott, HI, Schlossberg, ML, and Herzog, WR. "Regional and Systemic Platelet Function Is Altered by Myocardial Ischemia-Reperfusion." J Thromb Thrombolysis 1, no. 2 (1995): 187-194.  Link to Item
    • Gurbel, PA, and O'Connor, CM. "Zofenopril after anterior myocardial infarction." New England Journal of Medicine 332, no. 25 (1995): 1715--.
    • Gurbel, PA. "Letters to the editor." Catheterization and Cardiovascular Diagnosis 36, no. 4 (January 1, 1995): 377-377. (Letter)  Full Text
    • Herzog, WR, Gurbel, PA, Vogel, RA, Schlossberg, ML, Schneider, AI, and Serebruany, VL. "Effects of a Novel Leumedin NPC 15669 on Myocardial Stunning and Preconditioned Infarction Size in Swine." J Thromb Thrombolysis 1, no. 2 (1995): 163-170.  Link to Item
    • Serebruany, VL, Herzog, WR, Gurbel, PA, Schlossberg, ML, Scott, HJ, and Vogel, RA. "NPC 15669, an Antiinflammatory Leucine Derivative, Reduces In Vitro Platelet Aggregability in Both Swine and Human Plasma." J Thromb Thrombolysis 1, no. 2 (1995): 171-178.  Link to Item
    • Gurbel, PA, Anderson, RD, MacCord, CS, Scott, H, Serebruany, V, and Herzog, WR. "Accelerated intravenous dosing of recombinant tissue-type plasminogen activator causes rapid but unstable reperfusion in a canine model of acute myocardial infarction." Coron Artery Dis 5, no. 11 (November 1994): 929-936.  Link to Item
    • Ohman, EM, George, BS, White, CJ, Kern, MJ, Gurbel, PA, Freedman, RJ, Lundergan, C, Hartmann, JR, Talley, JD, and Frey, MJ. "Use of aortic counterpulsation to improve sustained coronary artery patency during acute myocardial infarction. Results of a randomized trial. The Randomized IABP Study Group." Circulation 90, no. 2 (August 1994): 792-799.  Full Text
    • Ohman, EM, Marquis, JF, Ricci, DR, Brown, RI, Knudtson, ML, Kereiakes, DJ, Samaha, JK, Margolis, JR, Niederman, AL, and Dean, LS. "A randomized comparison of the effects of gradual prolonged versus standard primary balloon inflation on early and late outcome. Results of a multicenter clinical trial. Perfusion Balloon Catheter Study Group." Circulation 89, no. 3 (March 1994): 1118-1125.  Full Text
    • Gurbel, PA, Anderson, RD, MacCord, CS, Scott, H, Komjathy, SF, Poulton, J, Stafford, JL, and Godard, J. "Arterial diastolic pressure augmentation by intra-aortic balloon counterpulsation enhances the onset of coronary artery reperfusion by thrombolytic therapy." Circulation 89, no. 1 (January 1994): 361-365.  Link to Item
    • Gurbel, PA, MacCord, CS, Anderson, RD, Scott, H, Atar, D, Mergner, W, and Herzog, WR. "A canine model of acute coronary artery thrombosis for the evaluation of reperfusion strategies." Cardiology 84, no. 1 (1994): 1-8.  Full Text  Link to Item
    • Tapson, VF, Gurbel, PA, Witty, LA, Pieper, KS, and Stack, RS. "Pharmacomechanical thrombolysis of experimental pulmonary emboli: Rapid low-dose intraembolic therapy." Chest 106, no. 5 (1994): 1558-1562.
    • Herzog, WR, Atar, D, Gurbel, PA, Vogel, RA, Schlossberg, ML, and Serebruany, VL. "Effect of magnesium sulphate infusion on ex vivo platelet aggregation in swine." Magnes Res 6, no. 4 (December 1993): 349-353.  Link to Item
    • Tapson, VF, Davidson, CJ, Gurbel, PA, Sheikh, KH, Kisslo, KB, and Stack, RS. "Rapid and accurate diagnosis of pulmonary emboli in a canine model using intravascular ultrasound imaging." Chest 100, no. 5 (1991): 1410-1413.
    • Gurbel, PA, Davidson, CJ, Ohman, EM, Smith, JE, and Stack, RS. "Selective infusion of thrombolytic therapy in the acute myocardial infarct-related coronary artery as an alternative to rescue percutaneous transluminal coronary angioplasty." Am J Cardiol 66, no. 12 (October 15, 1990): 1021-1023.  Link to Item
    • Hurwitz, JL, Kanter, RJ, Gurbel, P, Greenfield, RA, Kasell, JH, and Davidson, CJ. "AV blockade via selective AV nodal artery injection in a patient." Am Heart J 120, no. 4 (October 1990): 986-988.  Link to Item
    • Navetta, FI, Barber, MJ, Gurbel, PA, Moreadith, RW, Bernstein, R, Hlatky, MA, Coleman, RE, and Bashore, TM. "Myocardial ischemia in constrictive pericarditis." Am Heart J 116, no. 4 (October 1988): 1107-1111.  Link to Item
    • Haber, RH, Oddone, EZ, Gurbel, PA, and Stead, WW. "Acute pulmonary decompensation due to amphotericin B in the absence of granulocyte transfusions." The New England journal of medicine 315, no. 13 (September 1986): 836-. (Academic Article)
    • Navarese, EP, Gurbel, PA, Andreotti, F, Tantry, U, Jeong, Y-H, Kozinski, M, Engstrøm, T, Di Pasquale, G, Kochman, W, Ardissino, D, Kedhi, E, Stone, GW, and Kubica, J. "Optimal timing of coronary invasive strategy in non-ST-segment elevation acute coronary syndromes: a systematic review and meta-analysis." Ann Intern Med 158, no. 4: 261-270. (Review)  Full Text  Link to Item

  • Book Sections

    • Tantry, US, Myat, A, and Gurbel, PA. "Monitoring of antiplatelet therapy." In Platelets in Thrombotic and Non-Thrombotic Disorders: Pathophysiology, Pharmacology and Therapeutics: an Update, 671-679. March 8, 2017.  Full Text
    • Tantry, US, and Gurbel, PA. "Markers of platelet function." In New Therapeutic Agents in Thrombosis and Thrombolysis: Third Edition, 409-427. April 19, 2016.
    • Gurbel, PA, Gesheff, M, Bliden, KP, and Tantry, US. "Light Transmission Aggregometry." In Antiplatelet Therapy in Cardiovascular Disease, 51-57. June 3, 2014.  Full Text
    • Gurbel, PA, Jeong, YH, and Tantry, US. "Personalizing Antiplatelet Therapy." In Antiplatelet Therapy in Cardiovascular Disease, 267-276. June 3, 2014.  Full Text
    • Gurbel, PA, and Tantry, US. "Platelet Pathophysiology and its Role in Thrombosis." In Antiplatelet Therapy in Cardiovascular Disease, 1-7. June 3, 2014.  Full Text
    • Tantry, US, Bliden, KP, Meeran, T, and Gurbel, PA. "Clopidogrel Resistance." In Antiplatelet Therapy in Cardiovascular Disease, 285-292. June 3, 2014.  Full Text
    • Tantry, US, Doraiswamy, VA, Stokken, G, Slepian, MJ, and Gurbel, PA. "Thrombelastography and Other Novel Techniques." In Antiplatelet Therapy in Cardiovascular Disease, 102-107. June 3, 2014.  Full Text
    • Gurbel, PA, and Tantry, US. "Acute coronary syndromes." In New Oral Anticoagulants, 35-57. November 1, 2013.  Full Text
    • Gurbel, PA, and Tantry, US. "Antiplatelet drug resistance and variability in response: The role of antiplatelet therapy monitoring." In Antiplatelet and Anticoagulation Therapy, 45-112. January 1, 2013.  Full Text
    • Gurbel, PA, and Tantry, US. "Monitoring of Antiplatelet Therapy." In Platelets, 603-633.: Elsevier, 2013.  Full Text
    • Gurbel, PA, and Tantry, US. "Antithrombotic therapies." In Advances in Acute Coronary Syndrome Management, 45-66. March 1, 2012.  Full Text
    • Gurbel, PA, DiChiara, J, Antonino, MJ, and Tantry, US. "CRP and its role in coronary heart disease: New research developments." In C-Reactive Protein: New Research, 35-42. December 1, 2009.
    • "Thienopyridine Response Variability and Resistance." In Antiplatelet Therapy In Ischemic Heart Disease, 77-93. February 19, 2009.  Full Text
    • Reichman, J. "Preface." In Profili evolutivi del diritto Industriale. 2001. (Chapter)

  • Conference Papers

    • Mahla, E, Prueller, F, Farzi, S, Pregartner, G, Raggam, RB, Beran, E, Toller, W, Berghold, A, Tantry, US, and Gurbel, PA. "Does Platelet Reactivity Predict Bleeding in Patients Needing Urgent Coronary Artery Bypass Grafting During Dual Antiplatelet Therapy?." December 2016.  Full Text
    • Alexander, W, Gibson, CM, Hylek, EM, and Gurbel, P. "American Heart Association 2008 Scientific Sessions. The ATLAS TIMI 46 trial: Rivaroxaban." January 1, 2009.
    • Gurbel, PA, and Anderson, RD. "New concept in coronary angioplasty: Dilatation with a helical balloon that allows simultaneous autoperfusion." January 1997.  Link to Item

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