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Deep neural network for multiparametric ultrasound imaging of prostate cancer

Publication ,  Conference
Chan, DY; Morris, DC; Lye, T; Polascik, TJ; Palmeri, ML; Mamou, J; Nightingale, KR
Published in: IEEE International Ultrasonics Symposium, IUS
January 1, 2021

This study presents a deep neural network (DNN) for generating a multiparametric ultrasound (mpUS) volume of the prostate by combining data from acoustic radiation force impulse (ARFI) imaging, shear wave elasticity imaging (SWEI), B-mode imaging, and quantitative ultrasound-midband fit (QUS-MF). The DNN was trained using in vivo data to maximize the contrast-to-noise ratio between prostate cancer and healthy tissue. The network was evaluated in a prostate phantom, where the DNN was shown to increase the CNR of lesions as well as the CNR between the peripheral zone and the background. In a test in vivo dataset, the DNN improved the visibility of a histology-confirmed lesion. These findings suggest that deep learning may be a promising approach for providing enhanced imaging guidance during a biopsy of the prostate.

Duke Scholars

Published In

IEEE International Ultrasonics Symposium, IUS

DOI

EISSN

1948-5727

ISSN

1948-5719

Publication Date

January 1, 2021
 

Citation

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Chan, D. Y., Morris, D. C., Lye, T., Polascik, T. J., Palmeri, M. L., Mamou, J., & Nightingale, K. R. (2021). Deep neural network for multiparametric ultrasound imaging of prostate cancer. In IEEE International Ultrasonics Symposium, IUS. https://doi.org/10.1109/IUS52206.2021.9593332
Chan, D. Y., D. C. Morris, T. Lye, T. J. Polascik, M. L. Palmeri, J. Mamou, and K. R. Nightingale. “Deep neural network for multiparametric ultrasound imaging of prostate cancer.” In IEEE International Ultrasonics Symposium, IUS, 2021. https://doi.org/10.1109/IUS52206.2021.9593332.
Chan DY, Morris DC, Lye T, Polascik TJ, Palmeri ML, Mamou J, et al. Deep neural network for multiparametric ultrasound imaging of prostate cancer. In: IEEE International Ultrasonics Symposium, IUS. 2021.
Chan, D. Y., et al. “Deep neural network for multiparametric ultrasound imaging of prostate cancer.” IEEE International Ultrasonics Symposium, IUS, 2021. Scopus, doi:10.1109/IUS52206.2021.9593332.
Chan DY, Morris DC, Lye T, Polascik TJ, Palmeri ML, Mamou J, Nightingale KR. Deep neural network for multiparametric ultrasound imaging of prostate cancer. IEEE International Ultrasonics Symposium, IUS. 2021.

Published In

IEEE International Ultrasonics Symposium, IUS

DOI

EISSN

1948-5727

ISSN

1948-5719

Publication Date

January 1, 2021