Biosocial Theories of Crime
Role of genotype in the cycle of violence in maltreated children
Publication
, Chapter
Caspi, A; McClay, J; Moffitt, TE; Mill, J; Martin, J; Craig, IW; Taylor, A; Poulton, R
July 5, 2017
We studied a large sample of male children from birth to adulthood to determine why some children who are maltreated grow up to develop antisocial behavior, whereas others do not. A functional polymorphism in the gene encoding the neurotransmitter-metabolizing enzyme monoamine oxidase A (MAOA) was found to moderate the effect of maltreatment. Maltreated children with a genotype conferring high levels of MAOA expression were less likely to develop antisocial problems. These findings may partly explain why not all victims of maltreatment grow up to victimize others, and they provide epidemiological evidence that genotypes can moderate children's sensitivity to environmental insults.
Duke Scholars
ISBN
9780754629191
Publication Date
July 5, 2017
Start / End Page
205 / 208
Citation
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Caspi, A., McClay, J., Moffitt, T. E., Mill, J., Martin, J., Craig, I. W., … Poulton, R. (2017). Role of genotype in the cycle of violence in maltreated children. In Biosocial Theories of Crime (pp. 205–208).
Caspi, A., J. McClay, T. E. Moffitt, J. Mill, J. Martin, I. W. Craig, A. Taylor, and R. Poulton. “Role of genotype in the cycle of violence in maltreated children.” In Biosocial Theories of Crime, 205–8, 2017.
Caspi A, McClay J, Moffitt TE, Mill J, Martin J, Craig IW, et al. Role of genotype in the cycle of violence in maltreated children. In: Biosocial Theories of Crime. 2017. p. 205–8.
Caspi, A., et al. “Role of genotype in the cycle of violence in maltreated children.” Biosocial Theories of Crime, 2017, pp. 205–08.
Caspi A, McClay J, Moffitt TE, Mill J, Martin J, Craig IW, Taylor A, Poulton R. Role of genotype in the cycle of violence in maltreated children. Biosocial Theories of Crime. 2017. p. 205–208.
ISBN
9780754629191
Publication Date
July 5, 2017
Start / End Page
205 / 208