Overview
Caspi’s research is concerned with three questions: (1) How do childhood experiences shape aging and the course of health inequalities across the life span? (2) How do genetic differences between people shape the way they respond to their environments? (3) How do mental health problems unfold across and shape the life course?
Current Appointments & Affiliations
Edward M. Arnett Distinguished Professor of Psychology and Neuroscience
·
2008 - Present
Psychology & Neuroscience,
Trinity College of Arts & Sciences
Professor of Psychology and Neuroscience
·
2007 - Present
Psychology & Neuroscience,
Trinity College of Arts & Sciences
Professor in Psychiatry and Behavioral Sciences
·
2012 - Present
Psychiatry, Child & Family Mental Health & Community Psychiatry,
Psychiatry & Behavioral Sciences
Faculty Research Scholar of DuPRI's Population Research Center
·
2010 - Present
Duke Population Research Center,
Duke Population Research Institute
Faculty Research Scholar of DuPRI's Center for Population Health & Aging
·
2011 - Present
Center for Population Health & Aging,
Duke Population Research Institute
Recent Publications
Correction: DNA methylation profiles of long-term cannabis users in midlife: a comprehensive evaluation of published cannabis-associated methylation markers in a representative cohort.
Journal Article Mol Psychiatry · July 4, 2025 Full text Link to item CiteDunedinPACNI estimates the longitudinal Pace of Aging from a single brain image to track health and disease.
Journal Article Nature aging · July 2025 To understand how aging affects functional decline and increases disease risk, it is necessary to develop measures of how fast a person is aging. Using data from the Dunedin Study, we introduce an accurate and reliable measure for the rate of longitudinal ... Full text CiteAccelerated Epigenetic Aging and Prospective Morbidity and Mortality Among U.S. Veterans.
Journal Article J Gerontol A Biol Sci Med Sci · June 10, 2025 BACKGROUND: Epigenetic aging measures have promise as surrogate health outcomes in randomized control trials and observational cohort studies. The value of these measures, however, will reflect the extent to which they are associated with prospective healt ... Full text Link to item CiteRecent Grants
Duke-NCCU Interdisciplinary Postdoctoral Training Program in Child Psychiatric and Neurodevelopmental Conditions Program (DN-IPT)
Inst. Training Prgm or CMEPreceptor · Awarded by National Institutes of Health · 2024 - 2029Duke University Psychiatry Physician-Scientist Residency Training Program
Inst. Training Prgm or CMEMentor · Awarded by National Institute of Mental Health · 2024 - 2029Quantifying Individual Differences in Midlife Structural Brain Integrity Associated with Later AD/ADRD Risk
ResearchInvestigator · Awarded by National Institute on Aging · 2015 - 2027View All Grants
Education, Training & Certifications
Cornell University ·
1986
Ph.D.
Cornell University ·
1983
M.A.
University of California, Santa Cruz ·
1981
B.A.