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Avshalom Caspi

Edward M. Arnett Distinguished Professor of Psychology and Neuroscience
Psychology & Neuroscience
2020 W Main Street Suite 201, Box 104410, Durham, NC 27708
2020 W Main Street Suite 201, Box 104410, Durham, NC 27708

Overview


Caspi’s research is concerned with three questions: (1) How do childhood experiences shape aging and the course of health inequalities across the life span?  (2) How do genetic differences between people shape the way they respond to their environments? (3) How do mental health problems unfold across and shape the life course? 

Current Appointments & Affiliations


Edward M. Arnett Distinguished Professor of Psychology and Neuroscience · 2008 - Present Psychology & Neuroscience, Trinity College of Arts & Sciences
Professor of Psychology and Neuroscience · 2007 - Present Psychology & Neuroscience, Trinity College of Arts & Sciences
Professor in Psychiatry and Behavioral Sciences · 2012 - Present Psychiatry, Child & Family Mental Health & Community Psychiatry, Psychiatry & Behavioral Sciences
Faculty Research Scholar of DuPRI's Population Research Center · 2010 - Present Duke Population Research Center, Duke Population Research Institute
Faculty Research Scholar of DuPRI's Center for Population Health & Aging · 2011 - Present Center for Population Health & Aging, Duke Population Research Institute

In the News


Published January 13, 2025
How Fast Are You Aging? A ‘Speedometer’ Tells You
Published September 19, 2024
Mental Health Concerns Are a Huge Part of Primary Care Practice
Published March 14, 2024
Poor Neighborhoods Linked to Elevated Dementia Risk and Faster Brain Aging

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Recent Publications


DunedinPACNI estimates the longitudinal Pace of Aging from a single brain image to track health and disease.

Journal Article Nature aging · July 2025 To understand how aging affects functional decline and increases disease risk, it is necessary to develop measures of how fast a person is aging. Using data from the Dunedin Study, we introduce an accurate and reliable measure for the rate of longitudinal ... Full text Cite

Accelerated Epigenetic Aging and Prospective Morbidity and Mortality Among U.S. Veterans.

Journal Article J Gerontol A Biol Sci Med Sci · June 10, 2025 BACKGROUND: Epigenetic aging measures have promise as surrogate health outcomes in randomized control trials and observational cohort studies. The value of these measures, however, will reflect the extent to which they are associated with prospective healt ... Full text Link to item Cite
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Recent Grants


Duke-NCCU Interdisciplinary Postdoctoral Training Program in Child Psychiatric and Neurodevelopmental Conditions Program (DN-IPT)

Inst. Training Prgm or CMEPreceptor · Awarded by National Institutes of Health · 2024 - 2029

Duke University Psychiatry Physician-Scientist Residency Training Program

Inst. Training Prgm or CMEMentor · Awarded by National Institute of Mental Health · 2024 - 2029

Quantifying Individual Differences in Midlife Structural Brain Integrity Associated with Later AD/ADRD Risk

ResearchInvestigator · Awarded by National Institute on Aging · 2015 - 2027

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Education, Training & Certifications


Cornell University · 1986 Ph.D.
Cornell University · 1983 M.A.
University of California, Santa Cruz · 1981 B.A.