Skip to main content
Journal cover image

Velocity changes in femoral vessel ultrasound with Doppler in Porcine hemorrhagic shock.

Publication ,  Journal Article
Antonescu, I; Moore, B; Peethumnongsin, E; Montgomery, SP
Published in: Heliyon
January 15, 2024

OBJECTIVE: Physician-directed point-of-care ultrasound (PoCUS) is routinely used to identify the etiology of shock and guide therapy in the ICU. We performed a preclinical study to determine what changes are manifested in the femoral vessels during hemorrhagic shock on Duplex imaging and to generate a femoral vessel sonographic profile over the time course of shock. DESIGN & SETTING: A preclinical study in swine was performed using a convenience sample of animals that were being used in a Trauma Surgery training lab. The animals developed progressive unregulated hemorrhage during the lab. SUBJECTS: Six anesthetized swine underwent Duplex studies of the femoral vessels prior to any hemorrhage and at two time points after the start of hemorrhage. INTERVENTIONS: N/A. MEASUREMENTS: Femoral vessel imaging was performed using a portable ultrasound (Sonosite and Clarius). MAIN RESULTS: Femoral arterial peak systolic velocity decreased in all animals with hemorrhage, from a mean (SD) of 77 (27) cm/s pre-hemorrhage to 42 (17) and 32 (16) cm/s at the two post-hemorrhage time points. There were also changes to the arterial waveform morphology. Mean venous velocities also decreased with hemorrhage (20, 11, 7 cm/s). Animals with severe hemorrhage had a cessation of venous flow during positive pressure ventilation. CONCLUSION: In this preclinical study, both femoral peak systolic velocity and venous velocity decreased with hemorrhage. Femoral vessels represent an easily accessible target for non-invasive hemodynamic monitoring. Changes in femoral vessel Duplex waveforms and velocities should be studied both in a larger sample of animals with controlled hemorrhage and in human trauma patients to determine whether changes appear in early hemorrhage, before the onset of clinically evident hemorrhagic shock.

Duke Scholars

Altmetric Attention Stats
Dimensions Citation Stats

Published In

Heliyon

DOI

ISSN

2405-8440

Publication Date

January 15, 2024

Volume

10

Issue

1

Start / End Page

e23269

Location

England
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Antonescu, I., Moore, B., Peethumnongsin, E., & Montgomery, S. P. (2024). Velocity changes in femoral vessel ultrasound with Doppler in Porcine hemorrhagic shock. Heliyon, 10(1), e23269. https://doi.org/10.1016/j.heliyon.2023.e23269
Antonescu, Ioana, Brad Moore, Erica Peethumnongsin, and Sean P. Montgomery. “Velocity changes in femoral vessel ultrasound with Doppler in Porcine hemorrhagic shock.Heliyon 10, no. 1 (January 15, 2024): e23269. https://doi.org/10.1016/j.heliyon.2023.e23269.
Antonescu I, Moore B, Peethumnongsin E, Montgomery SP. Velocity changes in femoral vessel ultrasound with Doppler in Porcine hemorrhagic shock. Heliyon. 2024 Jan 15;10(1):e23269.
Antonescu, Ioana, et al. “Velocity changes in femoral vessel ultrasound with Doppler in Porcine hemorrhagic shock.Heliyon, vol. 10, no. 1, Jan. 2024, p. e23269. Pubmed, doi:10.1016/j.heliyon.2023.e23269.
Antonescu I, Moore B, Peethumnongsin E, Montgomery SP. Velocity changes in femoral vessel ultrasound with Doppler in Porcine hemorrhagic shock. Heliyon. 2024 Jan 15;10(1):e23269.
Journal cover image

Published In

Heliyon

DOI

ISSN

2405-8440

Publication Date

January 15, 2024

Volume

10

Issue

1

Start / End Page

e23269

Location

England