Bucket lists must be completed during cell death.
Publication
, Journal Article
Nozaki, K; Miao, EA
Published in: Trends in cell biology
September 2023
Regulated cell death occurs in many forms, including apoptosis, pyroptosis, necroptosis, and NETosis. Most obviously, the purpose of these pathways is to kill the cell. However, many cells need to complete a set of effector programs before they die, which we define as a cellular 'bucket list'. These effector programs are specific to the cell type, and mode and circumstances of death. For example, intestinal epithelial cells need to complete the process of extrusion before they die. Cells use regulatory mechanisms to temporarily prolong their life, including endosomal sorting complex required for transport (ESCRT)- and acid sphingomyelinase (ASM)-driven membrane repair. These allow cells to complete their bucket lists before they die.
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Published In
Trends in cell biology
DOI
EISSN
1879-3088
ISSN
0962-8924
Publication Date
September 2023
Volume
33
Issue
9
Start / End Page
803 / 815
Related Subject Headings
- Pyroptosis
- Protein Transport
- Humans
- Developmental Biology
- Cell Death
- Biological Transport
- Apoptosis
- 3101 Biochemistry and cell biology
- 11 Medical and Health Sciences
- 06 Biological Sciences
Citation
APA
Chicago
ICMJE
MLA
NLM
Nozaki, K., & Miao, E. A. (2023). Bucket lists must be completed during cell death. Trends in Cell Biology, 33(9), 803–815. https://doi.org/10.1016/j.tcb.2023.02.008
Nozaki, Kengo, and Edward A. Miao. “Bucket lists must be completed during cell death.” Trends in Cell Biology 33, no. 9 (September 2023): 803–15. https://doi.org/10.1016/j.tcb.2023.02.008.
Nozaki K, Miao EA. Bucket lists must be completed during cell death. Trends in cell biology. 2023 Sep;33(9):803–15.
Nozaki, Kengo, and Edward A. Miao. “Bucket lists must be completed during cell death.” Trends in Cell Biology, vol. 33, no. 9, Sept. 2023, pp. 803–15. Epmc, doi:10.1016/j.tcb.2023.02.008.
Nozaki K, Miao EA. Bucket lists must be completed during cell death. Trends in cell biology. 2023 Sep;33(9):803–815.
Published In
Trends in cell biology
DOI
EISSN
1879-3088
ISSN
0962-8924
Publication Date
September 2023
Volume
33
Issue
9
Start / End Page
803 / 815
Related Subject Headings
- Pyroptosis
- Protein Transport
- Humans
- Developmental Biology
- Cell Death
- Biological Transport
- Apoptosis
- 3101 Biochemistry and cell biology
- 11 Medical and Health Sciences
- 06 Biological Sciences