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Thermal Transformation of Alkenoylated Aziridines into Ring-Fused Pyrrolidines

Publication ,  Journal Article
Wenkert, D; Ferguson, SB; Porter, B; Qvarnstrom, A; McPhail, AT
Published in: Journal of Organic Chemistry
January 1, 1985

3-Phenyl- and 3-unsubstituted-2-alkenoyl-1-methylaziridines have been synthesized via Grignard reactions with the corresponding 2-cyanoaziridines. The 3-phenylated-2-alkenoylaziridines have been thermally transformed into ring-fused pyrrolidine compounds. The configurations and conformations of the aziridine and pyrrolidine compounds have been determined by 1H and 13C NMR spectroscopy and X-ray crystallography. © 1985, American Chemical Society. All rights reserved.

Duke Scholars

Published In

Journal of Organic Chemistry

DOI

EISSN

1520-6904

ISSN

0022-3263

Publication Date

January 1, 1985

Volume

50

Issue

21

Start / End Page

4114 / 4119

Related Subject Headings

  • Organic Chemistry
  • 3405 Organic chemistry
  • 3404 Medicinal and biomolecular chemistry
  • 0305 Organic Chemistry
  • 0304 Medicinal and Biomolecular Chemistry
 

Citation

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MLA
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Wenkert, D., Ferguson, S. B., Porter, B., Qvarnstrom, A., & McPhail, A. T. (1985). Thermal Transformation of Alkenoylated Aziridines into Ring-Fused Pyrrolidines. Journal of Organic Chemistry, 50(21), 4114–4119. https://doi.org/10.1021/jo00221a029
Wenkert, D., S. B. Ferguson, B. Porter, A. Qvarnstrom, and A. T. McPhail. “Thermal Transformation of Alkenoylated Aziridines into Ring-Fused Pyrrolidines.” Journal of Organic Chemistry 50, no. 21 (January 1, 1985): 4114–19. https://doi.org/10.1021/jo00221a029.
Wenkert D, Ferguson SB, Porter B, Qvarnstrom A, McPhail AT. Thermal Transformation of Alkenoylated Aziridines into Ring-Fused Pyrrolidines. Journal of Organic Chemistry. 1985 Jan 1;50(21):4114–9.
Wenkert, D., et al. “Thermal Transformation of Alkenoylated Aziridines into Ring-Fused Pyrrolidines.” Journal of Organic Chemistry, vol. 50, no. 21, Jan. 1985, pp. 4114–19. Scopus, doi:10.1021/jo00221a029.
Wenkert D, Ferguson SB, Porter B, Qvarnstrom A, McPhail AT. Thermal Transformation of Alkenoylated Aziridines into Ring-Fused Pyrrolidines. Journal of Organic Chemistry. 1985 Jan 1;50(21):4114–4119.
Journal cover image

Published In

Journal of Organic Chemistry

DOI

EISSN

1520-6904

ISSN

0022-3263

Publication Date

January 1, 1985

Volume

50

Issue

21

Start / End Page

4114 / 4119

Related Subject Headings

  • Organic Chemistry
  • 3405 Organic chemistry
  • 3404 Medicinal and biomolecular chemistry
  • 0305 Organic Chemistry
  • 0304 Medicinal and Biomolecular Chemistry