Current Appointments & Affiliations
Professor Emeritus of Chemistry
·
2004 - Present
Chemistry,
Trinity College of Arts & Sciences
Recent Publications
A highly stereoselective approach to novel 2,2,4-trisubstituted pyrrolidines by halocylization: Key intermediates towards syntheses of nitrogen analogs of Noxafil®
Journal Article Tetrahedron Letters · October 20, 2003 A convenient synthesis of novel 2,2,4-trisubstituted pyrrolidines via stereoselective 5-exo iodocyclization of the 2,2-disubstituted olefins 8 and 9 is described. Single crystal X-ray analysis of the oxazolidinone 15 confirmed the relative stereochemistry ... Full text CiteAn unusual acetonide group migration
Journal Article Tetrahedron Letters · September 15, 2003 Treatment of (2S,3R)-2,3-O-isopropyliden-4-penten-1,2,3-triol mesylate with uracil, K2CO3 did not provide the product of S N2 displacement, but an interesting acetonide group migration product 8. The structure of 8 was secu ... Full text CiteAsymmetric Synthesis of 4,4-Disubstituted-2-imidazolidinones: Potent NK1 Antagonists
Journal Article Organic Letters · 2003 CiteEducation, Training & Certifications
University of Glasgow (United Kingdom) ·
1963
Ph.D.
University of Glasgow (United Kingdom) ·
1959
B.S.