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Transcriptional control of cognitive development.

Publication ,  Journal Article
Hong, EJ; West, AE; Greenberg, ME
Published in: Curr Opin Neurobiol
February 2005

Cognitive development is determined by both genetics and environment. One point of convergence of these two influences is the neural activity-dependent regulation of programs of gene expression that specify neuronal fate and function. Human genetic studies have linked several transcriptional regulators to neurodevelopmental disorders including mental retardation and autism spectrum disorders. Recent reports on two such factors, CREB-binding protein and methyl-CpG-binding protein 2, have begun to reveal how epigenetics and neuronal activity act to modulate the program of gene expression required for synaptic development and function.

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Published In

Curr Opin Neurobiol

DOI

ISSN

0959-4388

Publication Date

February 2005

Volume

15

Issue

1

Start / End Page

21 / 28

Location

England

Related Subject Headings

  • Transcription, Genetic
  • Transcription Factors
  • Humans
  • Cognition Disorders
  • Cognition
  • Animals
  • 3209 Neurosciences
  • 1702 Cognitive Sciences
  • 1109 Neurosciences
 

Citation

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Hong, E. J., West, A. E., & Greenberg, M. E. (2005). Transcriptional control of cognitive development. Curr Opin Neurobiol, 15(1), 21–28. https://doi.org/10.1016/j.conb.2005.01.002
Hong, Elizabeth J., Anne E. West, and Michael E. Greenberg. “Transcriptional control of cognitive development.Curr Opin Neurobiol 15, no. 1 (February 2005): 21–28. https://doi.org/10.1016/j.conb.2005.01.002.
Hong EJ, West AE, Greenberg ME. Transcriptional control of cognitive development. Curr Opin Neurobiol. 2005 Feb;15(1):21–8.
Hong, Elizabeth J., et al. “Transcriptional control of cognitive development.Curr Opin Neurobiol, vol. 15, no. 1, Feb. 2005, pp. 21–28. Pubmed, doi:10.1016/j.conb.2005.01.002.
Hong EJ, West AE, Greenberg ME. Transcriptional control of cognitive development. Curr Opin Neurobiol. 2005 Feb;15(1):21–28.
Journal cover image

Published In

Curr Opin Neurobiol

DOI

ISSN

0959-4388

Publication Date

February 2005

Volume

15

Issue

1

Start / End Page

21 / 28

Location

England

Related Subject Headings

  • Transcription, Genetic
  • Transcription Factors
  • Humans
  • Cognition Disorders
  • Cognition
  • Animals
  • 3209 Neurosciences
  • 1702 Cognitive Sciences
  • 1109 Neurosciences