Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • M.D., Harvard University 1998
  • Ph.D., Harvard University 1998
  • B.A., Cornell University 1989
• 

  Previous Appointments & Affiliations

  • Associate Professor of Neurobiology, Neurobiology, Basic Science Departments 2013 - 2019
  • Assistant Professor of Neurobiology, Neurobiology, Basic Science Departments 2005 - 2013
• 

  Leadership & Clinical Positions at Duke

  • Associate Director, Medical Scientist Training Program
• Recognition
• 

  In the News

  • AUG 3, 2021

    Center for Advanced Genomic Technologies

    Two New Transgenic Mouse Lines Will Enable Innovative Studies Into Gene Regulation

  • DEC 10, 2014

    Genes Tell Story of Birdsong and Human Speech
• Research
• 

  Selected Grants

  • Roles for uniquely human enhancers in brain development and Wnt signaling awarded by National Institutes of Health 2023 - 2027
  • Duke Preparing Research Scholars in Biomedical Sciences- Post-Baccalaureate Research Education Program awarded by National Institutes of Health 2022 - 2027
  • Medical Scientist Training Program awarded by National Institutes of Health 2022 - 2027
  • Training Program in Developmental and Stem Cell Biology awarded by National Institutes of Health 2001 - 2027
  • Cell and Molecular Biology Training Program awarded by National Institutes of Health 2021 - 2026
  • Mechanisms Regulating Vascular Homeostasis awarded by National Institutes of Health 2021 - 2025
  • Genetic and Genomics Training Grant awarded by National Institutes of Health 2020 - 2025
  • Pharmacological Sciences Training Grant awarded by National Institutes of Health 2020 - 2025
  • Enhancer-mediated Bdnf Regulation awarded by National Institutes of Health 2022 - 2025
  • Orchestration of synaptic gene regulation by H3K27me3-dependent modulation of chromatin architecture awarded by Simons Foundation Autism Research Initiative 2023 - 2025
  • Combating obesity via cell-specific pharmacology of dopamine neurons awarded by  American Heart Association 2023 - 2024
  • Noncoding regulation of gene transcription in human neurons awarded by Ruth K. Broad Biomedical Research Foundation 2021 - 2024
  • Neurobiology Training Program awarded by National Institutes of Health 2019 - 2024
  • Functional and Mechanistic Dissection of GPCR Endosomal Signaling Dynamics awarded by National Institutes of Health 2022 - 2024
  • Using epigenome editing of transcriptional enhancers to regulate adult visual cortical plasticity awarded by National Institutes of Health 2022 - 2024
  • Psychostimulant-Induced Plasticity of Nucleus Accumbens Interneurons awarded by National Institutes of Health 2019 - 2024
  • Modulation of the Perineuronal Net Protein Brevican in the Nucleus Accumbens, and its Impact on Addiction-like Behavior awarded by National Institutes of Health 2020 - 2023
  • Epitranscriptomic Regulation of Synaptic Responses to Drugs of Abuse awarded by National Institutes of Health 2018 - 2023
  • IRES Track 1 IRTG Engaged in Dissecting and Reengineering the Regulatory Genome awarded by  National Science Foundation 2019 - 2023
  • Chromatin Mechanisms of Neuronal Maturation awarded by National Institutes of Health 2017 - 2023
  • Medical Scientist Training Program awarded by National Institutes of Health 1997 - 2022
  • The Role of the Lysine-Specific Histone Demethylase 6b, Kdm6b In Synapse Maturation awarded by National Institutes of Health 2019 - 2022
  • In Vivo Epigenome Editing with CRISPR-Based Histone Acetyltransferase Transgenic Mice awarded by National Institutes of Health 2016 - 2022
  • Bioinformatics and Computational Biology Training Program awarded by National Institutes of Health 2005 - 2021
  • Epigenome Editing Technologies to Control Diverse Biological Functions awarded by Allen Institute for Brain Science 2017 - 2021
  • HARDAC-M: Enabling memory-intensive computation for genomics awarded by North Carolina Biotechnology Center 2020 - 2021
  • Epigenomic modulation of psychostimulant-inducible Fosb in the nucleus accumbens awarded by National Institutes of Health 2020 - 2021
  • Genetics Training Grant awarded by National Institutes of Health 1979 - 2020
  • Organization and Function of Cellular Structure awarded by National Institutes of Health 1975 - 2020
  • Pharmacological Sciences Training Program awarded by National Institutes of Health 1975 - 2020
  • Basic predoctoral training in neuroscience awarded by National Institutes of Health 1992 - 2018
  • Regulation of Cocaine Reward and Reinforcement by MeCP2 awarded by National Institutes of Health 2013 - 2017
  • Genome-Wide Mapping of Enhancer Elements for Neuronal Differentiation Genes awarded by National Institutes of Health 2013 - 2016
  • Training in Fundamental &Translational Neuroscience awarded by National Institutes of Health 2005 - 2016
  • Amphetamine-Induced Transcriptional Plasticity in Striatal GABAergic Interneurons awarded by National Institutes of Health 2012 - 2015
  • Regulation of response to chronic antidepressant treatment by MeCP2 awarded by National Institutes of Health 2012 - 2014
  • Development of a Platform for Imaging Activity-Dependent Transcription in Neurons awarded by  National Science Foundation 2011 - 2013
  • Behavioral and Synaptic Consequences of MeCP2 Phosphorylation awarded by National Institutes of Health 2010 - 2011
  • Epigenetic regulation of transcriptional repression by drugs of abuse awarded by National Institutes of Health 2006 - 2011
  • A role for the epigenetic factor MeCP2 in neural response to psychostimulants awarded by National Institutes of Health 2008 - 2010
• 

  External Relationships

  • Massachusetts Institute of Technology
  • Michigan State University
  • University of Pennsylvania
  • Yale University
• Publications & Artistic Works
• 

  Selected Publications

  • Academic Articles

    • Ramesh, Vijyendra, Fang Liu, Melyssa S. Minto, Urann Chan, and Anne E. West. “Bidirectional regulation of postmitotic H3K27me3 distributions underlie cerebellar granule neuron maturation dynamics.” Elife 12 (April 24, 2023). https://doi.org/10.7554/eLife.86273.
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    • Green, Matthew V., David A. Gallegos, Jane-Valeriane Boua, Luke C. Bartelt, Arthy Narayanan, and Anne E. West. “Single-nucleus transcriptional profiling of GAD2-positive neurons from mouse lateral habenula reveals distinct expression of neurotransmission- and depression-related genes.” Biorxiv, January 9, 2023. https://doi.org/10.1101/2023.01.09.523312.
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    • Tremblay, Martine W., Matthew V. Green, Benjamin M. Goldstein, Andrew I. Aldridge, Jill A. Rosenfeld, Haley Streff, Wendy D. Tan, et al. “Mutations of the histone linker H1-4 in neurodevelopmental disorders and functional characterization of neurons expressing C-terminus frameshift mutant H1.4.” Hum Mol Genet 31, no. 9 (May 4, 2022): 1430–42. https://doi.org/10.1093/hmg/ddab321.
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    • Gallegos, David A., Melyssa Minto, Fang Liu, Mariah F. Hazlett, S. Aryana Yousefzadeh, Luke C. Bartelt, and Anne E. West. “Cell-type specific transcriptional adaptations of nucleus accumbens interneurons to amphetamine.” Mol Psychiatry, February 16, 2022. https://doi.org/10.1038/s41380-022-01466-1.
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    • Gemberling, Matthew P., Keith Siklenka, Erica Rodriguez, Katherine R. Tonn-Eisinger, Alejandro Barrera, Fang Liu, Ariel Kantor, et al. “Transgenic mice for in vivo epigenome editing with CRISPR-based systems.” Nat Methods 18, no. 8 (August 2021): 965–74. https://doi.org/10.1038/s41592-021-01207-2.
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    • Chan, Urann, Diwas Gautam, and Anne E. West. “Utilizing In Vivo Postnatal Electroporation to Study Cerebellar Granule Neuron Morphology and Synapse Development.” J Vis Exp, no. 172 (June 9, 2021). https://doi.org/10.3791/62568.
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    • Green, Matthew V., and Anne E. West. “TRPing into excitotoxic neuronal death.” Cell Calcium 93 (January 2021): 102331. https://doi.org/10.1016/j.ceca.2020.102331.
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    • Chen, Liang-Fu, Michelle R. Lyons, Fang Liu, Matthew V. Green, Nathan G. Hedrick, Ashley B. Williams, Arthy Narayanan, Ryohei Yasuda, and Anne E. West. “The NMDA receptor subunit GluN3A regulates synaptic activity-induced and myocyte enhancer factor 2C (MEF2C)-dependent transcription.” J Biol Chem 295, no. 25 (June 19, 2020): 8613–27. https://doi.org/10.1074/jbc.RA119.010266.
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    • Nord, Alex S., and Anne E. West. “Neurobiological functions of transcriptional enhancers.” Nat Neurosci 23, no. 1 (January 2020): 5–14. https://doi.org/10.1038/s41593-019-0538-5.
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    • Swahari, Vijay, and Anne E. West. “Histone demethylases in neuronal differentiation, plasticity, and disease.” Curr Opin Neurobiol 59 (December 2019): 9–15. https://doi.org/10.1016/j.conb.2019.02.009.
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    • West, Anne E. “Activity-Dependent Transcription Collaborates with Local Dendritic Translation to Encode Stimulus-Specificity in the Genome Binding of NPAS4.” Neuron 104, no. 4 (November 20, 2019): 634–36. https://doi.org/10.1016/j.neuron.2019.10.022.
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    • Tonn Eisinger, Katherine R., and Anne E. West. “Transcribing Memories in Genome Architecture.” Trends Neurosci 42, no. 9 (September 2019): 565–66. https://doi.org/10.1016/j.tins.2019.06.002.
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    • Kim, Namsoo, Haofang E. Li, Ryan N. Hughes, Glenn D. R. Watson, David Gallegos, Anne E. West, Il Hwan Kim, and Henry H. Yin. “A striatal interneuron circuit for continuous target pursuit.” Nat Commun 10, no. 1 (June 20, 2019): 2715. https://doi.org/10.1038/s41467-019-10716-w.
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    • Chen, Liang-Fu, Yen Ting Lin, David A. Gallegos, Mariah F. Hazlett, Mariana Gómez-Schiavon, Marty G. Yang, Breanna Kalmeta, et al. “Enhancer Histone Acetylation Modulates Transcriptional Bursting Dynamics of Neuronal Activity-Inducible Genes.” Cell Rep 26, no. 5 (January 29, 2019): 1174-1188.e5. https://doi.org/10.1016/j.celrep.2019.01.032.
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    • Gallegos, David A., Urann Chan, Liang-Fu Chen, and Anne E. West. “Chromatin Regulation of Neuronal Maturation and Plasticity.” Trends Neurosci 41, no. 5 (May 2018): 311–24. https://doi.org/10.1016/j.tins.2018.02.009.
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    • Wang, Xiaoting, David A. Gallegos, Vladimir M. Pogorelov, Justin K. O’Hare, Nicole Calakos, William C. Wetsel, and Anne E. West. “Parvalbumin Interneurons of the Mouse Nucleus Accumbens are Required For Amphetamine-Induced Locomotor Sensitization and Conditioned Place Preference.” Neuropsychopharmacology 43, no. 5 (April 2018): 953–63. https://doi.org/10.1038/npp.2017.178.
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    • Wijayatunge, Ranjula, Fang Liu, Karl B. Shpargel, Nicole J. Wayne, Urann Chan, Jane-Valeriane Boua, Terry Magnuson, and Anne E. West. “The histone demethylase Kdm6b regulates a mature gene expression program in differentiating cerebellar granule neurons.” Mol Cell Neurosci 87 (March 2018): 4–17. https://doi.org/10.1016/j.mcn.2017.11.005.
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    • West, Anne E. “Neurobiology: Domains to the rescue for Rett syndrome.” Nature 550, no. 7676 (October 19, 2017): 343–44. https://doi.org/10.1038/nature24151.
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    • Gómez-Schiavon, Mariana, Liang-Fu Chen, Anne E. West, and Nicolas E. Buchler. “BayFish: Bayesian inference of transcription dynamics from population snapshots of single-molecule RNA FISH in single cells.” Genome Biol 18, no. 1 (September 4, 2017): 164. https://doi.org/10.1186/s13059-017-1297-9.
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    • Chen, Liang-Fu, Allen S. Zhou, and Anne E. West. “Transcribing the connectome: roles for transcription factors and chromatin regulators in activity-dependent synapse development.” J Neurophysiol 118, no. 2 (August 1, 2017): 755–70. https://doi.org/10.1152/jn.00067.2017.
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    • Zannas, Anthony S., Jun H. Kim, and Anne E. West. “Regulation and function of MeCP2 Ser421 phosphorylation in U50488-induced conditioned place aversion in mice.” Psychopharmacology (Berl) 234, no. 6 (March 2017): 913–23. https://doi.org/10.1007/s00213-017-4527-7.
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    • Yang, Marty G., and Anne E. West. “Editing the Neuronal Genome: a CRISPR View of Chromatin Regulation in Neuronal Development, Function, and Plasticity.” Yale J Biol Med 89, no. 4 (December 2016): 457–70.
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    • Lyons, Michelle R., Liang-Fu Chen, Jie V. Deng, Caitlin Finn, Andreas R. Pfenning, Aditi Sabhlok, Kelli M. Wilson, and Anne E. West. “The transcription factor calcium-response factor limits NMDA receptor-dependent transcription in the developing brain.” J Neurochem 137, no. 2 (April 2016): 164–76. https://doi.org/10.1111/jnc.13556.
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    • Gray, Jesse M., Tae-Kyung Kim, Anne E. West, Alex S. Nord, Eirene Markenscoff-Papadimitriou, and Stavros Lomvardas. “Genomic Views of Transcriptional Enhancers: Essential Determinants of Cellular Identity and Activity-Dependent Responses in the CNS.” J Neurosci 35, no. 41 (October 14, 2015): 13819–26. https://doi.org/10.1523/JNEUROSCI.2622-15.2015.
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    • Norris, Kristi L., Rui Hao, Liang-Fu Chen, Chun-Hsiang Lai, Meghan Kapur, Peter J. Shaughnessy, Dennis Chou, et al. “Convergence of Parkin, PINK1, and α-Synuclein on Stress-induced Mitochondrial Morphological Remodeling.” J Biol Chem 290, no. 22 (May 29, 2015): 13862–74. https://doi.org/10.1074/jbc.M114.634063.
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    • Frank, Christopher L., Fang Liu, Ranjula Wijayatunge, Lingyun Song, Matthew T. Biegler, Marty G. Yang, Christopher M. Vockley, et al. “Regulation of chromatin accessibility and Zic binding at enhancers in the developing cerebellum.” Nat Neurosci 18, no. 5 (May 2015): 647–56. https://doi.org/10.1038/nn.3995.
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    • West, Anne E. “Cocaine shapes chromatin landscapes via Tet1.” Nat Neurosci 18, no. 4 (April 2015): 478–80. https://doi.org/10.1038/nn.3985.
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    • Whitney, Osceola, Andreas R. Pfenning, Jason T. Howard, Charles A. Blatti, Fang Liu, James M. Ward, Rui Wang, et al. “Core and region-enriched networks of behaviorally regulated genes and the singing genome.” Science 346, no. 6215 (December 12, 2014): 1256780. https://doi.org/10.1126/science.1256780.
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    • Wijayatunge, Ranjula, Liang-Fu Chen, Young May Cha, Anthony S. Zannas, Christopher L. Frank, and Anne E. West. “The histone lysine demethylase Kdm6b is required for activity-dependent preconditioning of hippocampal neuronal survival.” Mol Cell Neurosci 61 (July 2014): 187–200. https://doi.org/10.1016/j.mcn.2014.06.008.
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    • West, A. E., and V. Orlando. “Epigenetics in brain function.” Neuroscience 264 (April 4, 2014): 1–3. https://doi.org/10.1016/j.neuroscience.2014.02.001.
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    • Zannas, A. S., and A. E. West. “Epigenetics and the regulation of stress vulnerability and resilience.” Neuroscience 264 (April 4, 2014): 157–70. https://doi.org/10.1016/j.neuroscience.2013.12.003.
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    • Deng, Jie V., Yehong Wan, Xiaoting Wang, Sonia Cohen, William C. Wetsel, Michael E. Greenberg, Paul J. Kenny, Nicole Calakos, and Anne E. West. “MeCP2 phosphorylation limits psychostimulant-induced behavioral and neuronal plasticity.” J Neurosci 34, no. 13 (March 26, 2014): 4519–27. https://doi.org/10.1523/JNEUROSCI.2821-13.2014.
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    • Van Kanegan, Michael J., Dong Ning He, Denise E. Dunn, Peiying Yang, Robert A. Newman, Anne E. West, and Donald C. Lo. “BDNF mediates neuroprotection against oxygen-glucose deprivation by the cardiac glycoside oleandrin.” J Neurosci 34, no. 3 (January 15, 2014): 963–68. https://doi.org/10.1523/JNEUROSCI.2700-13.2014.
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    • Ghiretti, Amy E., Anna R. Moore, Rebecca G. Brenner, Liang-Fu Chen, Anne E. West, Nelson C. Lau, Stephen D. Van Hooser, and Suzanne Paradis. “Rem2 is an activity-dependent negative regulator of dendritic complexity in vivo.” J Neurosci 34, no. 2 (January 8, 2014): 392–407. https://doi.org/10.1523/JNEUROSCI.1328-13.2014.
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    • West, A. E., P. Pruunsild, and T. Timmusk. “Neurotrophins: transcription and translation.” Handb Exp Pharmacol 220 (2014): 67–100. https://doi.org/10.1007/978-3-642-45106-5_4.
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    • Agostino, P. V., R. -. K. Cheng, C. L. Williams, A. E. West, and W. H. Meck. “Acquisition of response thresholds for timed performance is regulated by a calcium-responsive transcription factor, CaRF.” Genes Brain Behav 12, no. 6 (August 2013): 633–44. https://doi.org/10.1111/gbb.12059.
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    • Schmidt, Heath D., Jacqueline F. McGinty, Anne E. West, and Ghazaleh Sadri-Vakili. “Epigenetics and psychostimulant addiction.” Cold Spring Harb Perspect Med 3, no. 3 (March 1, 2013): a012047. https://doi.org/10.1101/cshperspect.a012047.
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    • Gadalla, Kamal K. E., Mark E. S. Bailey, Rosemary C. Spike, Paul D. Ross, Kenton T. Woodard, Sahana Nagabhushan Kalburgi, Lavanya Bachaboina, et al. “Improved survival and reduced phenotypic severity following AAV9/MECP2 gene transfer to neonatal and juvenile male Mecp2 knockout mice.” Mol Ther 21, no. 1 (January 2013): 18–30. https://doi.org/10.1038/mt.2012.200.
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    • Hutchinson, Ashley N., Jay V. Deng, Sonia Cohen, and Anne E. West. “Phosphorylation of MeCP2 at Ser421 contributes to chronic antidepressant action.” J Neurosci 32, no. 41 (October 10, 2012): 14355–63. https://doi.org/10.1523/JNEUROSCI.2156-12.2012.
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    • Lyons, Michelle R., Charlotte M. Schwarz, and Anne E. West. “Members of the myocyte enhancer factor 2 transcription factor family differentially regulate Bdnf transcription in response to neuronal depolarization.” J Neurosci 32, no. 37 (September 12, 2012): 12780–85. https://doi.org/10.1523/JNEUROSCI.0534-12.2012.
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    • Su, Dan, Young May Cha, and Anne E. West. “Mutation of MeCP2 alters transcriptional regulation of select immediate-early genes.” Epigenetics 7, no. 2 (February 2012): 146–54. https://doi.org/10.4161/epi.7.2.18907.
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    • West, Anne E. “Regulated shuttling of the histone deacetylase HDAC5 to the nucleus may put a brake on cocaine addiction.” Neuron 73, no. 1 (January 12, 2012): 1–3. https://doi.org/10.1016/j.neuron.2011.12.016.
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    • Hutchinson, Ashley N., Jie V. Deng, Dipendra K. Aryal, William C. Wetsel, and Anne E. West. “Differential regulation of MeCP2 phosphorylation in the CNS by dopamine and serotonin.” Neuropsychopharmacology 37, no. 2 (January 2012): 321–37. https://doi.org/10.1038/npp.2011.190.
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    • Zhu, Y., M. R. Lyons, A. E. West, L. L. Satterwhite, and A. Wax. “Spectral-domain differential interference contrast (SD-DIC) microscopy for measuring live cell dynamics.” Biomedical Optics, Biomed 2012, January 1, 2012. https://doi.org/10.1364/biomed.2012.bm4b.5.
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    • Cohen, Sonia, Harrison W. Gabel, Martin Hemberg, Ashley N. Hutchinson, L Amanda Sadacca, Daniel H. Ebert, David A. Harmin, et al. “Genome-wide activity-dependent MeCP2 phosphorylation regulates nervous system development and function.” Neuron 72, no. 1 (October 6, 2011): 72–85. https://doi.org/10.1016/j.neuron.2011.08.022.
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    • Lyons, Michelle R., and Anne E. West. “Mechanisms of specificity in neuronal activity-regulated gene transcription.” Prog Neurobiol 94, no. 3 (August 2011): 259–95. https://doi.org/10.1016/j.pneurobio.2011.05.003.
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    • West, Anne E., and Michael E. Greenberg. “Neuronal activity-regulated gene transcription in synapse development and cognitive function.” Cold Spring Harb Perspect Biol 3, no. 6 (June 1, 2011). https://doi.org/10.1101/cshperspect.a005744.
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    • West, Anne E. “Biological functions and transcriptional targets of CaRF in neurons.” Cell Calcium 49, no. 5 (May 2011): 290–95. https://doi.org/10.1016/j.ceca.2011.04.003.
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    • Deng, Jie V., Ramona M. Rodriguiz, Ashley N. Hutchinson, Il-Hwan Kim, William C. Wetsel, and Anne E. West. “MeCP2 in the nucleus accumbens contributes to neural and behavioral responses to psychostimulants.” Nat Neurosci 13, no. 9 (September 2010): 1128–36. https://doi.org/10.1038/nn.2614.
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    • McDowell, Kelli A., Ashley N. Hutchinson, Sarah J. E. Wong-Goodrich, Matthew M. Presby, Dan Su, Ramona M. Rodriguiz, Krystal C. Law, Christina L. Williams, William C. Wetsel, and Anne E. West. “Reduced cortical BDNF expression and aberrant memory in Carf knock-out mice.” J Neurosci 30, no. 22 (June 2, 2010): 7453–65. https://doi.org/10.1523/JNEUROSCI.3997-09.2010.
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    • Pfenning, Andreas R., Tae-Kyung Kim, James M. Spotts, Martin Hemberg, Dan Su, and Anne E. West. “Genome-wide identification of calcium-response factor (CaRF) binding sites predicts a role in regulation of neuronal signaling pathways.” Plos One 5, no. 5 (May 27, 2010): e10870. https://doi.org/10.1371/journal.pone.0010870.
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    • Pfenning, A. R., T. K. Kim, J. M. Spotts, M. Hemberg, D. Su, and A. E. West. “Genome-wide identification of calcium-response factor (CaRF) binding sites predicts a role in regulation of neuronal signaling pathways.” Plos One 5, no. 5 (2010). https://doi.org/10.1371/journal.pone.0010870.
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    • Kokubo, Manabu, Masahiro Nishio, Thomas J. Ribar, Kristin A. Anderson, Anne E. West, and Anthony R. Means. “BDNF-mediated cerebellar granule cell development is impaired in mice null for CaMKK2 or CaMKIV.” J Neurosci 29, no. 28 (July 15, 2009): 8901–13. https://doi.org/10.1523/JNEUROSCI.0040-09.2009.
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    • West, Anne E. “Biological functions of activity-dependent transcription revealed.” Neuron 60, no. 4 (November 26, 2008): 523–25. https://doi.org/10.1016/j.neuron.2008.11.008.
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    • West, A. E. “Activity-dependent regulation of brain-derived neurotrophic factor transcription,” January 1, 2008, 155–73. https://doi.org/10.1007/978-0-387-73609-9_8.
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    • Pugazhenthi, Subbiah, Ketaki Phansalkar, Gerald Audesirk, Anne West, and Leigh Cabell. “Differential regulation of c-jun and CREB by acrolein and 4-hydroxynonenal.” Free Radic Biol Med 40, no. 1 (January 1, 2006): 21–34. https://doi.org/10.1016/j.freeradbiomed.2005.08.023.
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    • Hong, Elizabeth J., Anne E. West, and Michael E. Greenberg. “Transcriptional control of cognitive development.” Curr Opin Neurobiol 15, no. 1 (February 2005): 21–28. https://doi.org/10.1016/j.conb.2005.01.002.
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    • Chen, Wen G., Qiang Chang, Yingxi Lin, Alexander Meissner, Anne E. West, Eric C. Griffith, Rudolf Jaenisch, and Michael E. Greenberg. “Derepression of BDNF transcription involves calcium-dependent phosphorylation of MeCP2.” Science 302, no. 5646 (October 31, 2003): 885–89. https://doi.org/10.1126/science.1086446.
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    • Chen, Wen G., Anne E. West, Xu Tao, Gabriel Corfas, Marilyn N. Szentirmay, Michele Sawadogo, Charles Vinson, and Michael E. Greenberg. “Upstream stimulatory factors are mediators of Ca2+-responsive transcription in neurons.” J Neurosci 23, no. 7 (April 1, 2003): 2572–81. https://doi.org/10.1523/JNEUROSCI.23-07-02572.2003.
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    • West, Anne E., Eric C. Griffith, and Michael E. Greenberg. “Regulation of transcription factors by neuronal activity.” Nat Rev Neurosci 3, no. 12 (December 2002): 921–31. https://doi.org/10.1038/nrn987.
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    • Tao, Xu, Anne E. West, Wen G. Chen, Gabriel Corfas, and Michael E. Greenberg. “A calcium-responsive transcription factor, CaRF, that regulates neuronal activity-dependent expression of BDNF.” Neuron 33, no. 3 (January 31, 2002): 383–95. https://doi.org/10.1016/s0896-6273(01)00561-x.
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    • West, A. E. “Development: Fattening up the synapse.” Nature Reviews Neuroscience 3, no. 1 (January 1, 2002): 4. https://doi.org/10.1038/nrn711.
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    • West, A. E., W. G. Chen, M. B. Dalva, R. E. Dolmetsch, J. M. Kornhauser, A. J. Shaywitz, M. A. Takasu, X. Tao, and M. E. Greenberg. “Calcium regulation of neuronal gene expression.” Proc Natl Acad Sci U S A 98, no. 20 (September 25, 2001): 11024–31. https://doi.org/10.1073/pnas.191352298.
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    • Hughes, T. R., M. Mao, A. R. Jones, J. Burchard, M. J. Marton, K. W. Shannon, S. M. Lefkowitz, et al. “Expression profiling using microarrays fabricated by an ink-jet oligonucleotide synthesizer.” Nat Biotechnol 19, no. 4 (April 2001): 342–47. https://doi.org/10.1038/86730.
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    • Bonni, A., A. Brunet, A. E. West, S. R. Datta, M. A. Takasu, and M. E. Greenberg. “Cell survival promoted by the Ras-MAPK signaling pathway by transcription-dependent and -independent mechanisms.” Science 286, no. 5443 (November 12, 1999): 1358–62. https://doi.org/10.1126/science.286.5443.1358.
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    • West, A. E., C. Provoda, R. L. Neve, and K. M. Buckley. “Protein targeting in neurons and endocrine cells.” Advances in Pharmacology (San Diego, Calif.) 42 (1998): 247–49.
    • West, A. E., C. Provoda, R. L. Neve, and K. M. Buckley. “Protein targeting in neurons and endocrine cells.” Adv Pharmacol 42 (1998): 247–49. https://doi.org/10.1016/s1054-3589(08)60739-5.
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    • West, A. E., R. L. Neve, and K. M. Buckley. “Targeting of the synaptic vesicle protein synaptobrevin in the axon of cultured hippocampal neurons: evidence for two distinct sorting steps.” J Cell Biol 139, no. 4 (November 17, 1997): 917–27. https://doi.org/10.1083/jcb.139.4.917.
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    • West, A. E., R. L. Neve, and K. M. Buckley. “Identification of a somatodendritic targeting signal in the cytoplasmic domain of the transferrin receptor.” J Neurosci 17, no. 16 (August 15, 1997): 6038–47. https://doi.org/10.1523/JNEUROSCI.17-16-06038.1997.
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  • Conference Papers

    • West, Anne E. “Insights into the Roles of the Methyl-DNA Binding Protein MeCP2 in Addictive-like Behaviors.” In Neuropsychopharmacology, 38:S59–60. NATURE PUBLISHING GROUP, 2013.
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    • Zannas, Anthony S., Jay V. Deng, Ashley N. Hutchinson, William C. Wetsel, and Anne E. West. “Phosphorylation of MeCP2 in Reward-Related Circuits is Required for Amphetamine-Induced Conditioned Place Preference in Mice.” In Biological Psychiatry, 73:285S-285S. ELSEVIER SCIENCE INC, 2013.
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• Teaching & Mentoring
• 

  Recent Courses

  • NEUROBIO 393: Research Independent Study 2023
  • NEUROBIO 719: Concepts in Neuroscience I: Cellular and Molecular Neurobiology 2023
  • NEUROBIO 726S: Neurobiology Journal Club 2023
  • UPGEN 778B: University Program in Genetics and Genomics Biological Solutions Module Il 2023
  • NEUROBIO 393: Research Independent Study 2022
  • NEUROBIO 719: Concepts in Neuroscience I: Cellular and Molecular Neurobiology 2022
  • NEUROBIO 726S: Neurobiology Journal Club 2022
  • NEUROSCI 495: Research Independent Study 3 2022
  • NEUROBIO 393: Research Independent Study 2021
  • NEUROBIO 719: Concepts in Neuroscience I: Cellular and Molecular Neurobiology 2021
  • NEUROBIO 726S: Neurobiology Journal Club 2021
  • NEUROBIO 793: Research in Neurobiology 2021
  • NEUROSCI 493: Research Independent Study 1 2021
  • NEUROSCI 494: Research Independent Study 2 2021
• Scholarly, Clinical, & Service Activities
• 

  Outreach & Engaged Scholarship

  • Bass Connections Team Leader. Summer Neuroscience Program. 2022 - 2023  2022 - 2023
  • Summer Neuroscience Program Mentor. Summer Neuroscience Program. 2021 - 2022  2021 - 2022
  • Summer Neuroscience Program Mentor. Summer Neuroscience Program. 2020  2020
• 

  Service to the Profession

  • Participant. Faculty Curriculum on Anti-Racism. Duke Office of Faculty Advancement. January 11, 2021 - January 14, 2021  2021

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