Colony size can be used to determine the MIC of fluconazole for pathogenic yeasts.
Publication
, Journal Article
Xu, J; Vilgalys, R; Mitchell, TG
Published in: J Clin Microbiol
August 1998
This report describes a new statistical method for estimating the MIC of fluconazole for yeasts pathogenic to humans. This method is based on comparison of the colony sizes on solid media containing different concentrations of fluconazole. By this method, the MICs of fluconazole for 10 yeast strains were comparable to results obtained by the standard method recommended by the National Committee for Clinical Laboratory Standards. This method is simple to perform and easy to interpret. The turnaround time is faster than other methods. The method should be applicable to the determination MICs of other antifungal drugs for yeasts.
Duke Scholars
Published In
J Clin Microbiol
DOI
ISSN
0095-1137
Publication Date
August 1998
Volume
36
Issue
8
Start / End Page
2383 / 2385
Location
United States
Related Subject Headings
- Yeasts
- Mycoses
- Microbiology
- Microbial Sensitivity Tests
- Humans
- Fluconazole
- Dose-Response Relationship, Drug
- Colony Count, Microbial
- Antifungal Agents
- 3207 Medical microbiology
Citation
APA
Chicago
ICMJE
MLA
NLM
Xu, J., Vilgalys, R., & Mitchell, T. G. (1998). Colony size can be used to determine the MIC of fluconazole for pathogenic yeasts. J Clin Microbiol, 36(8), 2383–2385. https://doi.org/10.1128/JCM.36.8.2383-2385.1998
Xu, J., R. Vilgalys, and T. G. Mitchell. “Colony size can be used to determine the MIC of fluconazole for pathogenic yeasts.” J Clin Microbiol 36, no. 8 (August 1998): 2383–85. https://doi.org/10.1128/JCM.36.8.2383-2385.1998.
Xu J, Vilgalys R, Mitchell TG. Colony size can be used to determine the MIC of fluconazole for pathogenic yeasts. J Clin Microbiol. 1998 Aug;36(8):2383–5.
Xu, J., et al. “Colony size can be used to determine the MIC of fluconazole for pathogenic yeasts.” J Clin Microbiol, vol. 36, no. 8, Aug. 1998, pp. 2383–85. Pubmed, doi:10.1128/JCM.36.8.2383-2385.1998.
Xu J, Vilgalys R, Mitchell TG. Colony size can be used to determine the MIC of fluconazole for pathogenic yeasts. J Clin Microbiol. 1998 Aug;36(8):2383–2385.
Published In
J Clin Microbiol
DOI
ISSN
0095-1137
Publication Date
August 1998
Volume
36
Issue
8
Start / End Page
2383 / 2385
Location
United States
Related Subject Headings
- Yeasts
- Mycoses
- Microbiology
- Microbial Sensitivity Tests
- Humans
- Fluconazole
- Dose-Response Relationship, Drug
- Colony Count, Microbial
- Antifungal Agents
- 3207 Medical microbiology