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Alimentary tract complications after renal transplantation.

Publication ,  Journal Article
Meyers, WC; Harris, N; Stein, S; Brooks, M; Jones, RS; Thompson, WM; Stickel, DL; Seigler, HF
Published in: Ann Surg
October 1979

A computer analysis of post renal transplantation gastrointestinal problems was performed to identify important associated clinical factors. Thirty-seven per cent of all transplant recipients developed one or more significant problems. Hemorrhage, nondiverticular intestinal perforation, and esophagitis occurred most frequently in hospitalized patients. Pancreatitis, diverticulitis, and gastroduodenal perforation occurred characteristically in long-term survivors with well functioning allografts. Eleven of 32 HLA identical recipients treated with maintenance corticosteroids during stable kidney function developed gastrointestinal disease while only one of 13 HLA identical recipients not given maintenance steroids developed a problem, which strongly suggests a causal role for steroids in the development of late complications. The association of preexisting peptic ulcer and diverticular disease with hemorrhage and perforation supports previous recommendations that documented peptic ulcer disease or diverticulitis should be corrected surgically prior to transplantation.

Duke Scholars

Published In

Ann Surg

DOI

ISSN

0003-4932

Publication Date

October 1979

Volume

190

Issue

4

Start / End Page

535 / 542

Location

United States

Related Subject Headings

  • Transplantation, Homologous
  • Tissue Donors
  • Surgery
  • Postoperative Complications
  • Pancreatitis
  • Middle Aged
  • Kidney Transplantation
  • Intestinal Perforation
  • Immunosuppression Therapy
  • Humans
 

Citation

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Meyers, W. C., Harris, N., Stein, S., Brooks, M., Jones, R. S., Thompson, W. M., … Seigler, H. F. (1979). Alimentary tract complications after renal transplantation. Ann Surg, 190(4), 535–542. https://doi.org/10.1097/00000658-197910000-00013
Meyers, W. C., N. Harris, S. Stein, M. Brooks, R. S. Jones, W. M. Thompson, D. L. Stickel, and H. F. Seigler. “Alimentary tract complications after renal transplantation.Ann Surg 190, no. 4 (October 1979): 535–42. https://doi.org/10.1097/00000658-197910000-00013.
Meyers WC, Harris N, Stein S, Brooks M, Jones RS, Thompson WM, et al. Alimentary tract complications after renal transplantation. Ann Surg. 1979 Oct;190(4):535–42.
Meyers, W. C., et al. “Alimentary tract complications after renal transplantation.Ann Surg, vol. 190, no. 4, Oct. 1979, pp. 535–42. Pubmed, doi:10.1097/00000658-197910000-00013.
Meyers WC, Harris N, Stein S, Brooks M, Jones RS, Thompson WM, Stickel DL, Seigler HF. Alimentary tract complications after renal transplantation. Ann Surg. 1979 Oct;190(4):535–542.

Published In

Ann Surg

DOI

ISSN

0003-4932

Publication Date

October 1979

Volume

190

Issue

4

Start / End Page

535 / 542

Location

United States

Related Subject Headings

  • Transplantation, Homologous
  • Tissue Donors
  • Surgery
  • Postoperative Complications
  • Pancreatitis
  • Middle Aged
  • Kidney Transplantation
  • Intestinal Perforation
  • Immunosuppression Therapy
  • Humans