Hilliard Foster Seigler | Scholars@Duke

Hilliard Foster Seigler
Professor of Surgery

Our laboratory is involved with tumor immunobiology with special interest in human melanoma. The laboratory is current focusing on the cellular and humoral responses to melanoma tumor cell vaccines. We completed Duke University's first gene therapy program utilizing autologous melanoma cells transduced with the gene for human gamma interferon. The serological and cellular studies indicated that patients made a significant and measurable response to immunization with these gene-modified tumor cells. We immunized 100 patients with autologous dendritic cells pulsed with either autologous tumor lysate or specific melanoma tumor peptides. The cell-mediated immune response to the vaccines was addressed in a serial fashion. At the present time, we are evaluating HLA identical donor stem cells in an effort to produce graft vs. tumor responses in patients with metastatic melanoma.

Current Appointments & Affiliations

Professor of Surgery, Surgical Oncology, Surgery 1977

Contact Information

Box 3966 Med Ctr, Durham, NC 27710
Room 469 Seeley Mudd Bldg, Durham, NC 27710
seigl001@mc.duke.edu (919) 684-3942

Background
Education, Training, & Certifications
- M.D., University of North Carolina - Chapel Hill 1960
Previous Appointments & Affiliations
- Professor of Immunology in the Department of Immunology, Immunology, Basic Science Departments 1994 - 2018
- Professor of Immunology in the Department of Microbiology and Immunology, Molecular Genetics and Microbiology, Basic Science Departments 1991 - 1992
Research
Selected Grants
- Dendritic Cell Vaccine Against Melanoma awarded by National Institutes of Health 1997 - 1998
- Immunization - Gamma Ifn Transduced Autologous Melanoma awarded by National Institutes of Health 1996 - 1998
- Immunization With Gamma Ifn Transduced Autologous Melanoma awarded by National Institutes of Health 1995 - 1998
- Surrogate Markers Of Tumor Specific Immunity awarded by National Institutes of Health 1994 - 1998
- Immmunization With Ifn Transduced Autologous Melanoma awarded by National Institutes of Health 1994 - 1998
- Immunization With Gamma Interferon Transduced Autologous.. awarded by National Institutes of Health 1994 - 1998
- Molecularly-Defined Taa As Human Anti-Tumor Ctl Targets awarded by National Institutes of Health 1993 - 1997
- Molecularly-Defined Taa As Human Anti-Tumor Ctl Targets awarded by National Institutes of Health 1992 - 1997
- Molecularly-Defined Taa As Human Anti-Tumor Ctl Targets awarded by National Institutes of Health 1992 - 1997
- Diagnostics And New Therapeutics In Surgical Training awarded by National Institutes of Health 1993 - 1994
- Diagnostics And New Therapeutics In Surgical Oncology awarded by National Institutes of Health 1992 - 1994
- Diagnosis And New Therapeutics In Surgical Oncology awarded by National Institutes of Health 1991 - 1994
- Diagnosis And New Therapeutics In Surgical Oncology awarded by National Institutes of Health 1989 - 1991
- Diagnosis & New Therapeutics In Surgical Oncology awarded by National Institutes of Health 1985 - 1986
Publications & Artistic Works
Selected Publications
- Books
  - Shingleton, W. W., and H. F. Seigler. Management of recurrent melanoma of the extremity. Vol. vol.6, 1975.
- Academic Articles
  - Beasley, Georgia M., Paul Speicher, Ketan Sharma, Hilliard Seigler, April Salama, Paul Mosca, and Douglas S. Tyler. “Efficacy of repeat sentinel lymph node biopsy in patients who develop recurrent melanoma.” J Am Coll Surg 218, no. 4 (April 2014): 686–92. https://doi.org/10.1016/j.jamcollsurg.2013.12.025.
    Full Text Link to Item
  - Seigler, H. F. “Surgical training programs continue to evolve.” Journal of Surgical Radiology 3, no. 1 (December 21, 2012): 12–15.
  - Raymond, Amanda K., Georgia M. Beasley, Gloria Broadwater, Christina K. Augustine, James C. Padussis, Ryan Turley, Bercedis Peterson, Hilliard Seigler, Scott K. Pruitt, and Douglas S. Tyler. “Current trends in regional therapy for melanoma: lessons learned from 225 regional chemotherapy treatments between 1995 and 2010 at a single institution.” J Am Coll Surg 213, no. 2 (August 2011): 306–16. https://doi.org/10.1016/j.jamcollsurg.2011.03.013.
    Full Text Link to Item
  - Bhattacharya, Syamal D., Judson B. Williams, Sebastian G. de la Fuente, Paul C. Kuo, and Hilliard F. Seigler. “Does protected research time during general surgery training contribute to graduates' career choice?” Am Surg 77, no. 7 (July 2011): 907–10.
    Link to Item
  - Aldrink, Jennifer H., M Angelica Selim, Diana L. Diesen, Jeffrey Johnson, Scott K. Pruitt, Douglas S. Tyler, and Hilliard F. Seigler. “Pediatric melanoma: a single-institution experience of 150 patients.” J Pediatr Surg 44, no. 8 (August 2009): 1514–21. https://doi.org/10.1016/j.jpedsurg.2008.12.003.
    Full Text Link to Item
  - Beasley, Georgia M., Abigail Caudle, Rebecca P. Petersen, Nicole S. McMahon, James Padussis, Paul J. Mosca, Jonathan S. Zager, et al. “A multi-institutional experience of isolated limb infusion: defining response and toxicity in the US.” J Am Coll Surg 208, no. 5 (May 2009): 706–15. https://doi.org/10.1016/j.jamcollsurg.2008.12.019.
    Full Text Link to Item
  - Beasley, Georgia M., Rebecca P. Petersen, Jin Yoo, Nicole McMahon, Thomas Aloia, William Petros, Gretchen Sanders, et al. “Isolated limb infusion for in-transit malignant melanoma of the extremity: a well-tolerated but less effective alternative to hyperthermic isolated limb perfusion.” Ann Surg Oncol 15, no. 8 (August 2008): 2195–2205. https://doi.org/10.1245/s10434-008-9988-9.
    Full Text Link to Item
  - Dannull, Jens, Diem-Thu Lesher, Robert Holzknecht, Wenning Qi, Gabi Hanna, Hilliard Seigler, Douglas S. Tyler, and Scott K. Pruitt. “Immunoproteasome down-modulation enhances the ability of dendritic cells to stimulate antitumor immunity.” Blood 110, no. 13 (December 15, 2007): 4341–50. https://doi.org/10.1182/blood-2007-04-083188.
    Full Text Link to Item
  - Petersen, Rebecca P., Steven I. Hanish, John C. Haney, Charles C. Miller, William R. Burfeind, Douglas S. Tyler, Hilliard F. Seigler, Walter Wolfe, Thomas A. D’Amico, and David H. Harpole. “Improved survival with pulmonary metastasectomy: an analysis of 1720 patients with pulmonary metastatic melanoma.” J Thorac Cardiovasc Surg 133, no. 1 (January 2007): 104–10. https://doi.org/10.1016/j.jtcvs.2006.08.065.
    Full Text Link to Item
  - Onaitis, Mark, Kirk Ludwig, Anthony Perez-Tamayo, Marcia Gottfried, Linda Russell, Phillip Shadduck, Theodore Pappas, Hilliard F. Seigler, and Douglas S. Tyler. “The Kraske procedure: a critical analysis of a surgical approach for mid-rectal lesions.” J Surg Oncol 94, no. 3 (September 1, 2006): 194–202. https://doi.org/10.1002/jso.20591.
    Full Text Link to Item
  - Ravin, Adam G., Nancy Pickett, Jeffrey L. Johnson, Samuel R. Fisher, L Scott Levin, and Hilliard F. Seigler. “Melanoma of the ear: treatment and survival probabilities based on 199 patients.” Ann Plast Surg 57, no. 1 (July 2006): 70–76. https://doi.org/10.1097/01.sap.0000208960.96944.c9.
    Full Text Link to Item
  - Posther, Katherine E., M Angelica Selim, Paul J. Mosca, Wilma E. Stanley, Jeffrey L. Johnson, Douglas S. Tyler, and Hilliard F. Seigler. “Histopathologic characteristics, recurrence patterns, and survival of 129 patients with desmoplastic melanoma.” Ann Surg Oncol 13, no. 5 (May 2006): 728–39. https://doi.org/10.1245/ASO.2006.03.091.
    Full Text Link to Item
  - Gaca, Jeffrey G., Rebecca P. Petersen, Bercedis L. Peterson, David H. Harpole, Thomas A. D’Amico, Theodore N. Pappas, Hilliard F. Seigler, Walter G. Wolfe, and Douglas S. Tyler. “Pathologic nodal status predicts disease-free survival after neoadjuvant chemoradiation for gastroesophageal junction carcinoma.” Ann Surg Oncol 13, no. 3 (March 2006): 340–46. https://doi.org/10.1245/ASO.2006.02.023.
    Full Text Link to Item
  - Grichnik, James M., James A. Burch, Ryan D. Schulteis, Siqing Shan, Jie Liu, Timothy L. Darrow, Carol E. Vervaert, and Hilliard F. Seigler. “Melanoma, a tumor based on a mutant stem cell?” J Invest Dermatol 126, no. 1 (January 2006): 142–53. https://doi.org/10.1038/sj.jid.5700017.
    Full Text Link to Item
  - Sampson, J. H., T. D. Shafman, J. H. Carter, A. H. Friedman, and H. F. Seigler. “Brain metastases from malignant melanoma,” December 1, 2005, 430–38. https://doi.org/10.1016/B978-0-7216-8148-1.50059-0.
    Full Text
  - Aloia, Thomas A., Elizabeth Grubbs, Mark Onaitis, Paul J. Mosca, Tsung-Yen Cheng, Hilliard Seigler, and Douglas S. Tyler. “Predictors of outcome after hyperthermic isolated limb perfusion: role of tumor response.” Arch Surg 140, no. 11 (November 2005): 1115–20. https://doi.org/10.1001/archsurg.140.11.1115.
    Full Text Link to Item
  - Hall, Jennifer G., Christopher Herman, Jonathan L. Cook, Douglas Tyler, Hilliard F. Seigler, and Paul J. Mosca. “Melanoma arising in a skin graft.” Ann Plast Surg 54, no. 1 (January 2005): 92–96. https://doi.org/10.1097/01.sap.0000136974.62109.01.
    Full Text Link to Item
  - Seigler, Hilliard F. “Axillary lymph node dissection versus the sentinel lymph node technique in breast cancer.” Ann Surg 240, no. 1 (July 2004): 7–8. https://doi.org/10.1097/01.sla.0000132567.28613.a7.
    Full Text Link to Item
  - Seigler, Hilliard F. “Mucosal melanoma.” J Surg Oncol 86, no. 4 (July 1, 2004): 187–88. https://doi.org/10.1002/jso.20078.
    Full Text Link to Item
  - Czito, Brian G., Timothy J. Hong, Darrel P. Cohen, Douglas S. Tyler, Catherine G. Lee, Mitchell S. Anscher, Kirk A. Ludwig, et al. “A Phase I trial of preoperative eniluracil plus 5-fluorouracil and radiation for locally advanced or unresectable adenocarcinoma of the rectum and colon.” Int J Radiat Oncol Biol Phys 58, no. 3 (March 1, 2004): 779–85. https://doi.org/10.1016/S0360-3016(03)01567-0.
    Full Text Link to Item
  - Mosca, Paul J., Douglas S. Tyler, and Hilliard F. Seigler. “Surgical management of cutaneous melanoma: current practice and impact on prognosis.” Adv Surg 38 (2004): 85–119.
    Link to Item
  - Morse, Michael A., H Kim Lyerly, Timothy M. Clay, Omar Abdel-Wahab, Stephen Y. Chui, Jennifer Garst, Jared Gollob, et al. “Immunotherapy of surgical malignancies.” Curr Probl Surg 41, no. 1 (January 2004): 15–132. https://doi.org/10.1016/S0011384003001321.
    Full Text Link to Item
  - Kalady, Matthew F., Rebekah R. White, Jeffrey L. Johnson, Douglas S. Tyler, and Hilliard F. Seigler. “Thin melanomas: predictive lethal characteristics from a 30-year clinical experience.” Ann Surg 238, no. 4 (October 2003): 528–35. https://doi.org/10.1097/01.sla.0000090446.63327.40.
    Full Text Link to Item
  - Kypson, Alan P., Emilie Morphew, Relief Jones, Marcia R. Gottfried, and Hilliard F. Seigler. “Heterotopic ossification in rectal cancer: Rare finding with a novel proposed mechanism.” J Surg Oncol 82, no. 2 (February 2003): 132–36. https://doi.org/10.1002/jso.10181.
    Full Text Link to Item
  - Tyler, D. S., and H. F. Seigler. “Invited critique.” Archives of Surgery 138, no. 1 (January 1, 2003): 67.
  - Lysyi, M. V., and P. M. Zuzyak. “Combined hardening of composite materials based on aluminum.” Materials Science 38, no. 6 (November 1, 2002): 903–6. https://doi.org/10.1023/A:1024284423143.
    Full Text
  - Gamel, John W., Stephen L. George, Michael J. Edwards, and Hilliard F. Seigler. “The long-term clinical course of patients with cutaneous melanoma.” Cancer 95, no. 6 (September 15, 2002): 1286–93. https://doi.org/10.1002/cncr.10813.
    Full Text Link to Item
  - Huang, Li, Libing Feng, Limin Yang, Weiguo Zhou, Shouyuan Zhao, and Changben Li. “Screen and identification of proteins interacting with ADAM19 cytoplasmic tail.” Mol Biol Rep 29, no. 3 (September 2002): 317–23. https://doi.org/10.1023/a:1020409217215.
    Full Text Link to Item
  - Davies, Helen, Graham R. Bignell, Charles Cox, Philip Stephens, Sarah Edkins, Sheila Clegg, Jon Teague, et al. “Mutations of the BRAF gene in human cancer.” Nature 417, no. 6892 (June 27, 2002): 949–54. https://doi.org/10.1038/nature00766.
    Full Text Link to Item
  - White, Rebekah R., Wilma E. Stanley, Jeffrey L. Johnson, Douglas S. Tyler, and Hilliard F. Seigler. “Long-term survival in 2,505 patients with melanoma with regional lymph node metastasis.” Ann Surg 235, no. 6 (June 2002): 879–87. https://doi.org/10.1097/00000658-200206000-00017.
    Full Text Link to Item
  - Gonzàlez-Stawinski, Gonzalo V., Jason M. Rovak, Hilliard F. Seigler, John P. Grant, Matthew F. Kalady, Shanka Biswas, and Theodore N. Pappas. “Poor outcome and quality of life in female patients undergoing secondary surgery for recurrent peptic ulcer disease.” J Gastrointest Surg 6, no. 3 (2002): 396–402. https://doi.org/10.1016/s1091-255x(01)00029-4.
    Full Text Link to Item
  - Onaitis, M. W., R. B. Noone, R. Fields, H. Hurwitz, M. Morse, P. Jowell, K. McGrath, et al. “Complete response to neoadjuvant chemoradiation for rectal cancer does not influence survival.” Ann Surg Oncol 8, no. 10 (December 2001): 801–6. https://doi.org/10.1007/s10434-001-0801-2.
    Full Text Link to Item
  - Ackley, C. D., V. G. Prieto, R. C. Bentley, M. G. Horenstein, H. F. Seigler, and C. R. Shea. “Primary chondroid melanoma.” J Cutan Pathol 28, no. 9 (October 2001): 482–85. https://doi.org/10.1034/j.1600-0560.2001.028009482.x.
    Full Text Link to Item
  - Zennadi, R., Z. Abdel-Wahab, H. F. Seigler, and T. L. Darrow. “Generation of melanoma-specific, cytotoxic CD4(+) T helper 2 cells: requirement of both HLA-DR15 and Fas antigens on melanomas for their lysis by Th2 cells.” Cell Immunol 210, no. 2 (June 15, 2001): 96–105. https://doi.org/10.1006/cimm.2001.1809.
    Full Text Link to Item
  - White, R. R., T. J. Halperin, J. A. Olson, M. S. Soo, R. C. Bentley, and H. F. Seigler. “Impact of core-needle breast biopsy on the surgical management of mammographic abnormalities.” Ann Surg 233, no. 6 (June 2001): 769–77. https://doi.org/10.1097/00000658-200106000-00006.
    Full Text Link to Item
  - Onaitis, M. W., R. B. Noone, M. Hartwig, H. Hurwitz, M. Morse, P. Jowell, K. McGrath, et al. “Neoadjuvant chemoradiation for rectal cancer: analysis of clinical outcomes from a 13-year institutional experience.” Ann Surg 233, no. 6 (June 2001): 778–85. https://doi.org/10.1097/00000658-200106000-00007.
    Full Text Link to Item
  - Owen, S. A., L. L. Sanders, L. J. Edwards, H. F. Seigler, D. S. Tyler, and J. M. Grichnik. “Identification of higher risk thin melanomas should be based on Breslow depth not Clark level IV.” Cancer 91, no. 5 (March 1, 2001): 983–91.
    Link to Item
  - Vollmer, R. T. “The correlation of serial prostate specific antigen measurements with clinical outcome after external beam radiation therapy of patients for prostate carcinoma.” Cancer 91, no. 5 (March 1, 2001): 1063–65.
    Link to Item
  - Vollmer, R. T., and H. F. Seigler. “Using a continuous transformation of the Breslow thickness for prognosis in cutaneous melanoma.” Am J Clin Pathol 115, no. 2 (February 2001): 205–12. https://doi.org/10.1309/WAVR-560R-NU5E-4Q96.
    Full Text Link to Item
  - Kalady, M. F., D. C. White, R. C. Fields, R. E. Coleman, F. R. Schuler, H. F. Seigler, and D. S. Tyler. “Validation of delayed sentinel lymph node mapping for melanoma.” Cancer J 7, no. 6 (2001): 503–8.
    Link to Item
  - Vollmer, R. T., and H. F. Seigler. “A model for pretest probability of lymph node metastasis from cutaneous Melanoma.” Am J Clin Pathol 114, no. 6 (December 2000): 875–79. https://doi.org/10.1309/V1XY-TKBU-HP6P-BBVL.
    Full Text Link to Item
  - Onaitis, M. W., P. M. Kirshbom, T. Z. Hayward, F. J. Quayle, J. M. Feldman, H. F. Seigler, and D. S. Tyler. “Gastrointestinal carcinoids: characterization by site of origin and hormone production.” Ann Surg 232, no. 4 (October 2000): 549–56. https://doi.org/10.1097/00000658-200010000-00010.
    Full Text Link to Item
  - O’Leary, J. A., K. R. Berend, J. L. Johnson, L. S. Levin, and H. F. Seigler. “Subungual melanoma. A review of 93 cases with identification of prognostic variables.” Clin Orthop Relat Res, no. 378 (September 2000): 206–12.
    Link to Item
  - Tyler, D. S., M. Onaitis, A. Kherani, A. Hata, E. Nicholson, M. Keogan, S. Fisher, E. Coleman, and H. F. Seigler. “Positron emission tomography scanning in malignant melanoma.” Cancer 89, no. 5 (September 1, 2000): 1019–25.
    Link to Item
  - Uchitomi, Y., I. Mikami, A. Kugaya, N. Akizuki, K. Nagai, Y. Nishiwaki, T. Akechi, and H. Okamura. “Depression after successful treatment for nonsmall cell lung carcinoma.” Cancer 89, no. 5 (September 1, 2000): 1172–79. https://doi.org/10.1002/1097-0142(20000901)89:5<1172::aid-cncr27>3.0.co;2-u.
    Full Text Link to Item
  - Yang, S., D. Kittlesen, C. L. Slingluff, C. E. Vervaert, H. F. Seigler, and T. L. Darrow. “Dendritic cells infected with a vaccinia vector carrying the human gp100 gene simultaneously present multiple specificities and elicit high-affinity T cells reactive to multiple epitopes and restricted by HLA-A2 and -A3.” J Immunol 164, no. 8 (April 15, 2000): 4204–11. https://doi.org/10.4049/jimmunol.164.8.4204.
    Full Text Link to Item
  - Dong, X. D., D. Tyler, J. L. Johnson, P. DeMatos, and H. F. Seigler. “Analysis of prognosis and disease progression after local recurrence of melanoma.” Cancer 88, no. 5 (March 1, 2000): 1063–71. https://doi.org/10.1002/(sici)1097-0142(20000301)88:5<1063::aid-cncr17>3.0.co;2-e.
    Full Text Link to Item
  - Yang, S., C. E. Vervaert, J. Burch, J. Grichnik, H. F. Seigler, and T. L. Darrow. “Murine dendritic cells transfected with human GP100 elicit both antigen-specific CD8(+) and CD4(+) T-cell responses and are more effective than DNA vaccines at generating anti-tumor immunity.” Int J Cancer 83, no. 4 (November 12, 1999): 532–40. https://doi.org/10.1002/(sici)1097-0215(19991112)83:4<532::aid-ijc16>3.0.co;2-k.
    Full Text Link to Item
  - White, D. C., F. R. Schuler, S. K. Pruitt, D. K. Culhane, H. F. Seigler, R. E. Coleman, and D. Tyler. “Timing of sentinel lymph node mapping after lymphoscintigraphy.” Surgery 126, no. 2 (August 1999): 156–61.
    Link to Item
  - Dong, X. D., Z. Abdel-Wahab, P. Dematos, T. Fong, S. K. Pruitt, and H. F. Seigler. “MCA106 fibrosarcoma cells transduced with granulocyte/macrophage colony-stimulating factor are not superior to the wild-type cells in suppressing the growth of hepatic metastases.” J Surg Oncol 71, no. 1 (May 1999): 36–45. https://doi.org/10.1002/(sici)1096-9098(199905)71:1<36::aid-jso8>3.0.co;2-x.
    Full Text Link to Item
  - Dematos, P., and H. F. Seigler. “Monitoring antitumour immune response during immunotherapy of cancer: why and how?” Biodrugs 11, no. 4 (April 1999): 239–47. https://doi.org/10.2165/00063030-199911040-00003.
    Full Text Link to Item
  - Yang, S., C. E. Vervaert, H. F. Seigler, and T. L. Darrow. “Tumor cells cotransduced with B7.1 and gamma-IFN induce effective rejection of established parental tumor.” Gene Ther 6, no. 2 (February 1999): 253–62. https://doi.org/10.1038/sj.gt.3300820.
    Full Text Link to Item
  - Dong, X. D., P. DeMatos, V. G. Prieto, and H. F. Seigler. “Melanoma of the gallbladder: a review of cases seen at Duke University Medical Center.” Cancer 85, no. 1 (January 1, 1999): 32–39.
    Link to Item
  - DeMatos, P., D. S. Tyler, and H. F. Seigler. “Malignant melanoma of the mucous membranes: a review of 119 cases.” Ann Surg Oncol 5, no. 8 (December 1998): 733–42. https://doi.org/10.1007/BF02303485.
    Full Text Link to Item
  - Mooney, E. E., H. F. Seigler, and L. J. Layfield. “Reporting fine-needle aspirates of breast: a survey of preferences among surgeons.” Diagn Cytopathol 19, no. 4 (October 1998): 317–20. https://doi.org/10.1002/(sici)1097-0339(199810)19:4<317::aid-dc20>3.0.co;2-p.
    Full Text Link to Item
  - DeMatos, P., D. Tyler, and H. F. Seigler. “Mucosal melanoma of the female genitalia: a clinicopathologic study of forty-three cases at Duke University Medical Center.” Surgery 124, no. 1 (July 1998): 38–48.
    Link to Item
  - DeMatos, P., Z. Abdel-Wahab, C. Vervaert, D. Hester, and H. Seigler. “Pulsing of dendritic cells with cell lysates from either B16 melanoma or MCA-106 fibrosarcoma yields equally effective vaccines against B16 tumors in mice.” J Surg Oncol 68, no. 2 (June 1998): 79–91. https://doi.org/10.1002/(sici)1096-9098(199806)68:2<79::aid-jso3>3.0.co;2-h.
    Full Text Link to Item
  - Abdel-Wahab, Z., P. DeMatos, D. Hester, X. D. Dong, and H. F. Seigler. “Human dendritic cells, pulsed with either melanoma tumor cell lysates or the gp100 peptide(280-288), induce pairs of T-cell cultures with similar phenotype and lytic activity.” Cell Immunol 186, no. 1 (May 25, 1998): 63–74. https://doi.org/10.1006/cimm.1998.1298.
    Full Text Link to Item
  - DeMatos, P., Z. Abdel-Wahab, C. Vervaert, and H. F. Seigler. “Vaccination with dendritic cells inhibits the growth of hepatic metastases in B6 mice.” Cell Immunol 185, no. 1 (April 10, 1998): 65–74. https://doi.org/10.1006/cimm.1998.1277.
    Full Text Link to Item
  - Sampson, J. H., J. H. Carter, A. H. Friedman, and H. F. Seigler. “Demographics, prognosis, and therapy in 702 patients with brain metastases from malignant melanoma.” J Neurosurg 88, no. 1 (January 1998): 11–20. https://doi.org/10.3171/jns.1998.88.1.0011.
    Full Text Link to Item
  - DeMatos, P., W. G. Wolfe, C. R. Shea, V. G. Prieto, and H. F. Seigler. “Primary malignant melanoma of the esophagus.” J Surg Oncol 66, no. 3 (November 1997): 201–6. https://doi.org/10.1002/(sici)1096-9098(199711)66:3<201::aid-jso9>3.0.co;2-g.
    Full Text Link to Item
  - Abdel-Wahab, Z., C. Weltz, D. Hester, N. Pickett, C. Vervaert, J. R. Barber, D. Jolly, and H. F. Seigler. “A Phase I clinical trial of immunotherapy with interferon-gamma gene-modified autologous melanoma cells: monitoring the humoral immune response.” Cancer 80, no. 3 (August 1, 1997): 401–12. https://doi.org/10.1002/(sici)1097-0142(19970801)80:3<401::aid-cncr8>3.0.co;2-u.
    Full Text Link to Item
  - Yang, S., T. L. Darrow, C. E. Vervaert, and H. F. Seigler. “Immunotherapeutic potential of tumor antigen-pulsed and unpulsed dendritic cells generated from murine bone marrow.” Cell Immunol 179, no. 1 (July 10, 1997): 84–95. https://doi.org/10.1006/cimm.1997.1151.
    Full Text Link to Item
  - Yang, S., T. L. Darrow, and H. F. Seigler. “Generation of primary tumor-specific cytotoxic T lymphocytes from autologous and human lymphocyte antigen class I-matched allogeneic peripheral blood lymphocytes by B7 gene-modified melanoma cells.” Cancer Res 57, no. 8 (April 15, 1997): 1561–68.
    Link to Item
  - Seigler, H. F. “Advances in the care of the patient with malignant melanoma.” Ann Surg 225, no. 1 (January 1997): 15–16. https://doi.org/10.1097/00000658-199701000-00002.
    Full Text Link to Item
  - Abdel-Wahab, Z., M. Dar, S. Osanto, T. Fong, C. E. Vervaert, D. Hester, D. Jolly, and H. F. Seigler. “Eradication of melanoma pulmonary metastases by immunotherapy with tumor cells engineered to secrete interleukin-2 or gamma interferon.” Cancer Gene Ther 4, no. 1 (1997): 33–41.
    Link to Item
  - Darrow, T. L., Z. Abdel-Wahab, M. A. Quinn-Allen, and H. F. Seigler. “Recognition and lysis of human melanoma by a CD3+, CD4+, CD8- T-cell clone restricted by HLA-A2.” Cell Immunol 172, no. 1 (August 25, 1996): 52–59. https://doi.org/10.1006/cimm.1996.0214.
    Full Text Link to Item
  - Abdel-Wahab, Z., M. M. Dar, D. Hester, C. Vervaert, R. Gangavalli, J. Barber, T. L. Darrow, and H. F. Seigler. “Effect of irradiation on cytokine production, MHC antigen expression, and vaccine potential of interleukin-2 and interferon-gamma gene-modified melanoma cells.” Cell Immunol 171, no. 2 (August 1, 1996): 246–54. https://doi.org/10.1006/cimm.1996.0200.
    Full Text Link to Item
  - CHARI, RAVI S., DOUGLAS S. TYLER, MITCHELL S. ANSCHER, L. I. N. D. A. RUSSEL, BRYAN M. CLARY, J. A. M. E. S. HATHORN, and HILLIARD F. SEIGLER. “Letter to the Editor.” Annals of Surgery 224, no. 1 (July 1996): 109–109. https://doi.org/10.1097/00000658-199607000-00025.
    Full Text
  - Dar, M. M., Z. Abdel-Wahab, C. E. Vervaert, T. Darrow, J. Barber, and H. F. Seigler. “Immunological memory induced by genetically transduced tumor cells.” Ann Surg Oncol 3, no. 3 (May 1996): 247–54. https://doi.org/10.1007/BF02306279.
    Full Text Link to Item
  - Stidham, K. R., W. M. Ricci, C. Vervaert, Z. Abdel-Wahab, H. F. Seigler, and T. L. Darrow. “Modulation of specific active immunization against murine melanoma using recombinant cytokines.” Surg Oncol 5, no. 5–6 (1996): 221–29. https://doi.org/10.1016/s0960-7404(96)80025-9.
    Full Text Link to Item
  - Reintgen, D., C. Slingluff, J. Wong, and H. F. Seigler. “Pregnancy in association with malignant melanoma.” Clinical Consultations in Obstetrics and Gynecology 7, no. 4 (December 1, 1995): 257–67.
  - Darrow, T. L., Z. Abdel-Wahab, and H. F. Seigler. “Immunotherapy of Human Melanoma With Gene-Modified Tumor Cell Vaccines.” Cancer Control 2, no. 5 (October 1995): 415–23. https://doi.org/10.1177/107327489500200505.
    Full Text Link to Item
  - Spiegel, D. A., J. H. Sampson, W. J. Richardson, A. H. Friedman, E. Rossitch, W. T. Hardaker, and H. F. Seigler. “Metastatic melanoma to the spine. Demographics, risk factors, and prognosis in 114 patients.” Spine (Phila Pa 1976) 20, no. 19 (October 1, 1995): 2141–46. https://doi.org/10.1097/00007632-199510000-00013.
    Full Text Link to Item
  - Chari, R. S., D. S. Tyler, M. S. Anscher, L. Russell, B. M. Clary, J. Hathorn, and H. F. Seigler. “Preoperative radiation and chemotherapy in the treatment of adenocarcinoma of the rectum.” Ann Surg 221, no. 6 (June 1995): 778–86. https://doi.org/10.1097/00000658-199506000-00016.
    Full Text Link to Item
  - Reintgen, D., C. W. Cruse, K. Wells, C. Berman, N. Fenske, F. Glass, K. Schroer, R. Heller, M. Ross, and G. Lyman. “The orderly progression of melanoma nodal metastases.” Ann Surg 220, no. 6 (December 1994): 759–67. https://doi.org/10.1097/00000658-199412000-00009.
    Full Text Link to Item
  - Abdel-Wahab, Z., W. P. Li, S. Osanto, T. L. Darrow, J. Hessling, C. E. Vervaert, M. Burrascano, J. Barber, and H. F. Seigler. “Transduction of human melanoma cells with interleukin-2 gene reduces tumorigenicity and enhances host antitumor immunity: a nude mouse model.” Cell Immunol 159, no. 1 (November 1994): 26–39. https://doi.org/10.1006/cimm.1994.1292.
    Full Text Link to Item
  - Abdel-Wahab, Z. A., S. Osanto, T. L. Darrow, J. R. Barber, C. E. Vervaert, R. Gangavalli, T. J. McCallister, and H. F. Seigler. “Transduction of human melanoma cells with the gamma interferon gene enhances cellular immunity.” Cancer Gene Ther 1, no. 3 (September 1994): 171–79.
    Link to Item
  - Davidoff, A. M., C. Cirrincione, and H. F. Seigler. “Malignant melanoma in children.” Ann Surg Oncol 1, no. 4 (July 1994): 278–82. https://doi.org/10.1007/BF02303565.
    Full Text Link to Item
  - Barnes, B. C., H. F. Seigler, T. S. Saxby, M. S. Kocher, and J. M. Harrelson. “Melanoma of the foot.” J Bone Joint Surg Am 76, no. 6 (June 1994): 892–98. https://doi.org/10.2106/00004623-199406000-00013.
    Full Text Link to Item
  - Seigler, H. F., T. L. Darrow, Z. Abdel-Wahab, R. Gangavalli, and J. Barber. “A phase I trial of human gamma interferon transduced autologous tumor cells in patients with disseminated malignant melanoma.” Hum Gene Ther 5, no. 6 (June 1994): 761–77. https://doi.org/10.1089/hum.1994.5.6-761.
    Full Text Link to Item
  - Stidham, K. R., J. L. Johnson, and H. F. Seigler. “Survival superiority of females with melanoma. A multivariate analysis of 6383 patients exploring the significance of gender in prognostic outcome.” Arch Surg 129, no. 3 (March 1994): 316–24. https://doi.org/10.1001/archsurg.1994.01420270094020.
    Full Text Link to Item
  - Slingluff, C. L., K. R. Stidham, W. M. Ricci, W. E. Stanley, and H. F. Seigler. “Surgical management of regional lymph nodes in patients with melanoma. Experience with 4682 patients.” Ann Surg 219, no. 2 (February 1994): 120–30. https://doi.org/10.1097/00000658-199402000-00003.
    Full Text Link to Item
  - Husain, I., J. L. Mohler, H. F. Seigler, and J. M. Besterman. “Elevation of topoisomerase I messenger RNA, protein, and catalytic activity in human tumors: demonstration of tumor-type specificity and implications for cancer chemotherapy.” Cancer Res 54, no. 2 (January 15, 1994): 539–46.
    Link to Item
  - Shaw, H. M., W. H. McCarthy, J. F. Thompson, K. R. Stidham, J. L. Johnson, and H. F. Seigler. “Survival superiority of females with melanoma.” Archives of Surgery 129, no. 12 (1994): 1343–44.
  - Abdel-Wahab, Z., W. P. Li, T. Darrow, E. D. Nudelman, A. Towell, and H. F. Seigler. “Cell surface reactive human monoclonal antibody directed to human melanoma-associated gangliosides.” Melanoma Res 3, no. 6 (December 1993): 415–23. https://doi.org/10.1097/00008390-199311000-00004.
    Full Text Link to Item
  - Seigler, H. F. “Surgical margins around primary cutaneous melanomas.” Ann Surg 218, no. 5 (November 1993): 702.
    Link to Item
  - Gamel, J. W., S. L. George, W. E. Stanley, and H. F. Seigler. “Skin melanoma. Cured fraction and survival time as functions of thickness, site, histologic type, age, and sex.” Cancer 72, no. 4 (August 15, 1993): 1219–23. https://doi.org/10.1002/1097-0142(19930815)72:4<1219::aid-cncr2820720414>3.0.co;2-0.
    Full Text Link to Item
  - Meisenberg, B. R., M. Ross, J. J. Vredenburgh, R. Jones, E. J. Shpall, H. F. Seigler, D. M. Coniglio, K. Wu, and W. P. Peters. “Randomized trial of high-dose chemotherapy with autologous bone marrow support as adjuvant therapy for high-risk, multi-node-positive malignant melanoma.” J Natl Cancer Inst 85, no. 13 (July 7, 1993): 1080–85. https://doi.org/10.1093/jnci/85.13.1080.
    Full Text Link to Item
  - Langford, F. P., S. R. Fisher, D. W. Molter, and H. F. Seigler. “Lentigo maligna melanoma of the head and neck.” Laryngoscope 103, no. 5 (May 1993): 520–24. https://doi.org/10.1288/00005537-199305000-00007.
    Full Text Link to Item
  - Wolfe, W. G., A. L. Vaughn, H. F. Seigler, J. W. Hathorn, K. A. Leopold, and F. G. Duhaylongsod. “Survival of patients with carcinoma of the esophagus treated with combined-modality therapy.” J Thorac Cardiovasc Surg 105, no. 4 (April 1993): 749–55.
    Link to Item
  - Slingluff, C. L., R. T. Vollmer, and H. F. Seigler. “Multiple primary melanoma: incidence and risk factors in 283 patients.” Surgery 113, no. 3 (March 1993): 330–39.
    Link to Item
  - Sampson, J. H., A. H. Friedman, H. F. Seigler, and J. H. Carter. “Epidural spinal metastases from malignant melanoma: Demographics, prognosis and treatment.” Canadian Journal of Neurological Sciences 20:S25 (1993).
  - Seigler, H. F. “Clinicopathologic factors relating to surgical margins for cutaneous melanoma.” Ann Surg 217, no. 1 (January 1993): 1. https://doi.org/10.1097/00000658-199301000-00001.
    Full Text Link to Item
  - Seigler, H. F. “Letter to the editor [5].” Annals of Surgery 218, no. 5 (January 1, 1993): 702.
  - Crowley, N. J., and H. F. Seigler. “Possibilities of immunotherapy and gene therapy for malignant melanoma.” Semin Surg Oncol 9, no. 3 (1993): 273–78.
    Link to Item
  - Reintgen, D., M. Ross, K. Bland, H. F. Seigler, and C. Balch. “Prevention and early detection of melanoma: a surgeon's perspective.” Semin Surg Oncol 9, no. 3 (1993): 174–87.
    Link to Item
  - Crowley, N. J., and H. F. Seigler. “Relationship between disease-free interval and survival in patients with recurrent melanoma.” Arch Surg 127, no. 11 (November 1992): 1303–8. https://doi.org/10.1001/archsurg.1992.01420110045011.
    Full Text Link to Item
  - Slingluff, C. L., R. K. Dodge, W. E. Stanley, and H. F. Seigler. “The annual risk of melanoma progression. Implications for the concept of cure.” Cancer 70, no. 7 (October 1, 1992): 1917–27. https://doi.org/10.1002/1097-0142(19921001)70:7<1917::aid-cncr2820700719>3.0.co;2-5.
    Full Text Link to Item
  - Fisher, S. R., J. Langford, D. W. Molter, and H. F. Seigler. “Thin malignant melanomas of the head and neck.” Laryngoscope 102, no. 8 (August 1992): 850–54. https://doi.org/10.1288/00005537-199208000-00002.
    Full Text Link to Item
  - Abdel-Wahab, Z. A., T. L. Darrow, C. E. Vervaert, A. A. Giannopoulou, W. Li, and H. F. Seigler. “Inhibition of the growth of human melanoma metastases in nude mice by melanoma-specific murine monoclonal antibody.” Surg Oncol 1, no. 2 (April 1992): 115–25. https://doi.org/10.1016/0960-7404(92)90024-f.
    Full Text Link to Item
  - Harpole, D. H., C. M. Johnson, W. G. Wolfe, S. L. George, and H. F. Seigler. “Analysis of 945 cases of pulmonary metastatic melanoma.” J Thorac Cardiovasc Surg 103, no. 4 (April 1992): 743–48.
    Link to Item
  - Darrow, T. L., Z. Wahab, M. A. Quinn-Allen, and H. F. Seigler. “Human melanoma-mediated inhibition of autologous CD4+ helper tumor-infiltrating lymphocyte growth in vitro.” Cancer 69, no. 7 (April 1, 1992): 1843–49. https://doi.org/10.1002/1097-0142(19920401)69:7<1843::aid-cncr2820690728>3.0.co;2-d.
    Full Text Link to Item
  - Crowley, N. J., C. E. Vervaert, and H. F. Seigler. “Human xenograft-nude mouse model of adoptive immunotherapy with human melanoma-specific cytotoxic T-cells.” Cancer Res 52, no. 2 (January 15, 1992): 394–99.
    Link to Item
  - Abdel-wahab, Z. A., W. E. Gillanders, T. L. Darrow, and H. F. Seigler. “Generation of human IgG, IgA, and IgM anti-melanoma monoclonal antibodies utilizing lymphocytes of an actively immunized melanoma patient.” Hum Antibodies Hybridomas 3, no. 1 (January 1992): 32–39.
    Link to Item
  - Reintgen, D. S., C. Cox, C. L. Slingluff, and H. F. Seigler. “Recurrent malignant melanoma: the identification of prognostic factors to predict survival.” Ann Plast Surg 28, no. 1 (January 1992): 45–49. https://doi.org/10.1097/00000637-199201000-00013.
    Full Text Link to Item
  - Slingluff, C. L., and H. F. Seigler. “Prospects for cellular immunotherapy for metastatic melanoma.” Ann Plast Surg 28, no. 1 (January 1992): 110–13. https://doi.org/10.1097/00000637-199201000-00028.
    Full Text Link to Item
  - Slingluff, C. L., and H. F. Seigler. “Immunotherapy for malignant melanoma with a tumor cell vaccine.” Ann Plast Surg 28, no. 1 (January 1992): 104–7. https://doi.org/10.1097/00000637-199201000-00026.
    Full Text Link to Item
  - Slingluff, C. L., and H. F. Seigler. “Malignant melanoma and pregnancy.” Ann Plast Surg 28, no. 1 (January 1992): 95–99. https://doi.org/10.1097/00000637-199201000-00024.
    Full Text Link to Item
  - Slingluff, C. L., and H. F. Seigler. “"Thin" malignant melanoma: risk factors and clinical management.” Ann Plast Surg 28, no. 1 (January 1992): 89–94. https://doi.org/10.1097/00000637-199201000-00023.
    Full Text Link to Item
  - Fisher, S. R., H. F. Seigler, and S. L. George. “Therapeutic and prognostic considerations of head and neck melanoma.” Ann Plast Surg 28, no. 1 (January 1992): 78–80. https://doi.org/10.1097/00000637-199201000-00020.
    Full Text Link to Item
  - Slingluff, C. L., and H. F. Seigler. “Anorectal melanoma: clinical characteristics and the role of abdominoperineal resection.” Ann Plast Surg 28, no. 1 (January 1992): 85–88. https://doi.org/10.1097/00000637-199201000-00022.
    Full Text Link to Item
  - Herzberg, A. J., B. J. Kerns, M. J. Borowitz, H. F. Seigler, and R. B. Kinney. “DNA ploidy of malignant melanoma determined by image cytometry of fresh frozen and paraffin-embedded tissue.” J Cutan Pathol 18, no. 6 (December 1991): 440–48. https://doi.org/10.1111/j.1600-0560.1991.tb01382.x.
    Full Text Link to Item
  - Branum, G. D., and H. F. Seigler. “Role of surgical intervention in the management of intestinal metastases from malignant melanoma.” Am J Surg 162, no. 5 (November 1991): 428–31. https://doi.org/10.1016/0002-9610(91)90254-b.
    Full Text Link to Item
  - Crowley, N. J., R. Dodge, R. T. Vollmer, and H. F. Seigler. “Malignant melanoma in black Americans. A trend toward improved survival.” Arch Surg 126, no. 11 (November 1991): 1359–64. https://doi.org/10.1001/archsurg.1991.01410350049008.
    Full Text Link to Item
  - Abdel-Wahab, Z., T. Darrow, C. E. Vervaert, N. J. Crowley, and H. F. Seigler. “Cell binding and tumor inhibiting functions of a new antihuman melanoma murine monoclonal antibody.” Mol Biother 3, no. 3 (September 1991): 163–69.
    Link to Item
  - Crowley, N. J., C. E. Vervaert, and H. F. Seigler. “Treatment of human melanoma hepatic metastases in nude mice with human cytotoxic T lymphocytes.” Arch Surg 126, no. 4 (April 1991): 433–37. https://doi.org/10.1001/archsurg.1991.01410280031003.
    Full Text Link to Item
  - Crowley, N. J., T. L. Darrow, M. A. Quinn-Allen, and H. F. Seigler. “MHC-restricted recognition of autologous melanoma by tumor-specific cytotoxic T cells. Evidence for restriction by a dominant HLA-A allele.” J Immunol 146, no. 5 (March 1, 1991): 1692–99.
    Link to Item
  - Branum, G. D., R. E. Epstein, G. S. Leight, and H. F. Seigler. “The role of resection in the management of melanoma metastatic to the adrenal gland.” Surgery 109, no. 2 (February 1991): 127–31.
    Link to Item
  - Reintgen, D., J. Becker, and H. F. Seigler. “Experimental trials of immunotherapy for malignant melanoma.” Semin Surg Oncol 7, no. 4 (1991): 192–98. https://doi.org/10.1002/ssu.2980070404.
    Full Text Link to Item
  - Crowley, N. J., and H. F. Seigler. “The role of elective lymph node dissection in the management of patients with thick cutaneous melanoma.” Cancer 66, no. 12 (December 15, 1990): 2522–27. https://doi.org/10.1002/1097-0142(19901215)66:12<2522::aid-cncr2820661213>3.0.co;2-z.
    Full Text Link to Item
  - Crowley, N. J., C. E. Vervaert, and H. F. Seigler. “Efficacy of human tumor-specific cytotoxic T cells in the treatment of human melanoma hepatic metastases in nude mice.” Surgical Forum 41 (December 1, 1990): 432–34.
  - Slingluff, C. L., R. Vollmer, and H. F. Seigler. “Acral melanoma: a review of 185 patients with identification of prognostic variables.” J Surg Oncol 45, no. 2 (October 1990): 91–98. https://doi.org/10.1002/jso.2930450207.
    Full Text Link to Item
  - Slingluff, C. L., H. F. Seigler, T. L. Darrow, and C. H. Evans. “Implications of leukoregulin to autologous tumor-specific human T-cell populations.” J Biol Response Mod 9, no. 4 (August 1990): 387–94.
    Link to Item
  - Crowley, N. J., and H. F. Seigler. “Late recurrence of malignant melanoma. Analysis of 168 patients.” Ann Surg 212, no. 2 (August 1990): 173–77. https://doi.org/10.1097/00000658-199008000-00010.
    Full Text Link to Item
  - Green, D. M., T. V. Samulski, C. Vervaert, E. C. Halperin, J. R. Oleson, and H. Seigler. “Effects of hyperthermia and irradiation on the growth of mouse melanoma tumors following immunotherapy.” J Surg Oncol 44, no. 4 (August 1990): 256–59. https://doi.org/10.1002/jso.2930440413.
    Full Text Link to Item
  - Slingluff, C. L., D. S. Reintgen, R. T. Vollmer, and H. F. Seigler. “Malignant melanoma arising during pregnancy. A study of 100 patients.” Ann Surg 211, no. 5 (May 1990): 552–57. https://doi.org/10.1097/00000658-199005000-00005.
    Full Text Link to Item
  - Crowley, N. J., C. L. Slingluff, T. L. Darrow, and H. F. Seigler. “Generation of human autologous melanoma-specific cytotoxic T-cells using HLA-A2-matched allogeneic melanomas.” Cancer Res 50, no. 3 (February 1, 1990): 492–98.
    Link to Item
  - Crowley, N. J., C. L. Slingluff, C. E. Vervaert, T. L. Darrow, and H. F. Seigler. “Inhibition of the growth of human melanoma xenografts in nude mice by human tumor-specific cytotoxic T-cells.” J Surg Oncol 43, no. 2 (February 1990): 67–72. https://doi.org/10.1002/jso.2930430202.
    Full Text Link to Item
  - Darrow, T. L., M. A. Quinn-Allen, N. J. Crowley, and H. F. Seigler. “Modulation of in vitro autologous melanoma-specific cytotoxic T-cell responses by phorbol dibutyrate and ionomycin.” Cell Immunol 125, no. 2 (February 1990): 508–17. https://doi.org/10.1016/0008-8749(90)90103-x.
    Full Text Link to Item
  - Akwari, O. E., A. Tucker, H. F. Seigler, and K. M. Itani. “Hepatobiliary cystadenoma with mesenchymal stroma.” Ann Surg 211, no. 1 (January 1990): 18–27. https://doi.org/10.1097/00000658-199001000-00004.
    Full Text Link to Item
  - Slingluff, C. L., R. T. Vollmer, and H. F. Seigler. “Anorectal melanoma: clinical characteristics and results of surgical management in twenty-four patients.” Surgery 107, no. 1 (January 1990): 1–9.
    Link to Item
  - Fisher, S. R., R. Cameron, D. J. Hoyt, T. B. Cole, H. F. Seigler, and W. C. Meyers. “Free jejunal interposition graft for reconstruction of the esophagus.” Head Neck 12, no. 2 (1990): 126–30. https://doi.org/10.1002/hed.2880120206.
    Full Text Link to Item
  - Crowley, N. J., T. L. Darrow, and H. F. Seigler. “Generation of autologous tumor-specific cytotoxic T-cells using allogeneic melanomas: Restriction by a dominant HLA-A region antigen.” Surgical Forum 40 (December 1, 1989): 438–40.
  - Knechtle, S. J., D. C. Castle, H. F. Seigler, and R. R. Bollinger. “Renal transplantation in the American black.” Transplant Proc 21, no. 6 (December 1989): 3931–33.
    Link to Item
  - Slingluff, C. L., T. L. Darrow, and H. F. Seigler. “Melanoma-specific cytotoxic T cells generated from peripheral blood lymphocytes. Implications of a renewable source of precursors for adoptive cellular immunotherapy.” Ann Surg 210, no. 2 (August 1989): 194–202. https://doi.org/10.1097/00000658-198908000-00010.
    Full Text Link to Item
  - Darrow, T. L., C. L. Slingluff, and H. F. Seigler. “The role of HLA class I antigens in recognition of melanoma cells by tumor-specific cytotoxic T lymphocytes. Evidence for shared tumor antigens.” J Immunol 142, no. 9 (May 1, 1989): 3329–35.
    Link to Item
  - Reintgen, D. S., R. Vollmer, and H. F. Seigler. “Juvenile malignant melanoma.” Surg Gynecol Obstet 168, no. 3 (March 1989): 249–53.
    Link to Item
  - Seigler, H. F., M. K. Wallack, C. E. Vervaert, J. A. Bash, K. M. Roberson, and G. M. Stuhlmiller. “Melanoma patient antibody responses to melanoma tumor-associated antigens defined by murine monoclonal antibodies.” J Biol Response Mod 8, no. 1 (February 1989): 37–52.
    Link to Item
  - Crowley, N. J., T. L. Darrow, and H. F. Seigler. “Generation of autologous tumor-specific cytotoxic T-cells using HLA-A region matched allogeneic melanoma.” Curr Surg 46, no. 5 (1989): 393–96.
    Link to Item
  - Stuhlmiller, G. M., K. M. Roberson, and H. F. Seigler. “Serological response of non-human primates to human melanoma disialoganglioside GD3.” Cancer Immunol Immunother 29, no. 3 (1989): 205–10. https://doi.org/10.1007/BF00199997.
    Full Text Link to Item
  - Slingluff, C. L., R. Vollmer, and H. F. Seigler. “Stage II malignant melanoma: presentation of a prognostic model and an assessment of specific active immunotherapy in 1,273 patients.” J Surg Oncol 39, no. 3 (November 1988): 139–47. https://doi.org/10.1002/jso.2930390302.
    Full Text Link to Item
  - Slingluff, C. L., T. Darrow, C. Vervaert, M. A. Quinn-Allen, and H. F. Seigler. “Human cytotoxic T cells specific for autologous melanoma cells: successful generation from lymph node cells in seven consecutive cases.” J Natl Cancer Inst 80, no. 13 (September 7, 1988): 1016–26. https://doi.org/10.1093/jnci/80.13.1016.
    Full Text Link to Item
  - SHOUP, S. A., J. W. TELLO, H. F. SEIGLER, W. W. JOHNSTON, J. SCHLOM, D. D. BIGNER, and S. H. BIGNER. “THE IMMUNOCYTOCHEMICAL DIAGNOSIS OF METASTATIC MELANOMA IN CYTOLOGIC SPECIMENS.” Acta Cytologica 32, no. 5 (September 1, 1988): 781–781.
    Link to Item
  - Slingluff, C. L., R. T. Vollmer, D. S. Reintgen, and H. F. Seigler. “Lethal "thin" malignant melanoma. Identifying patients at risk.” Ann Surg 208, no. 2 (August 1988): 150–61. https://doi.org/10.1097/00000658-198808000-00004.
    Full Text Link to Item
  - Darrow, T. L., C. L. Slingluff, and H. F. Seigler. “Autologous lymph node cell-derived tumor-specific cytotoxic T-cells for use in adoptive immunotherapy of human melanoma.” Cancer 62, no. 1 (July 1, 1988): 84–91. https://doi.org/10.1002/1097-0142(19880701)62:1<84::aid-cncr2820620116>3.0.co;2-r.
    Full Text Link to Item
  - Fisher, S. R., D. S. Reintgen, and H. F. Seigler. “Juvenile malignant melanoma of the head and neck.” Laryngoscope 98, no. 2 (February 1988): 184–89. https://doi.org/10.1288/00005537-198802000-00013.
    Full Text Link to Item
  - Johnston, W. W., H. F. Seigler, and M. D. Perry. “Fine needle aspiration biopsy of metastatic melanoma.” Cancer Treat Res 43 (1988): 103–22. https://doi.org/10.1007/978-1-4613-1751-7_7.
    Full Text Link to Item
  - Mahvi, D. M., H. F. Seigler, W. C. Meyers, H. Kalthoff, W. H. Schmiegel, and R. S. Metzgar. “DU-PAN-2 levels in serum and pancreatic ductal fluids of patients with benign and malignant pancreatic disease.” Pancreas 3, no. 4 (1988): 488–93. https://doi.org/10.1097/00006676-198808000-00020.
    Full Text Link to Item
  - Genkins, S. M., J. A. Tucker, H. F. Seigler, and N. R. Dunnick. “Biliary cystadenoma with mesenchymal stroma: CT and angiographic appearance.” J Comput Assist Tomogr 12, no. 3 (1988): 527–29. https://doi.org/10.1097/00004728-198805010-00039.
    Full Text Link to Item
  - Peters, W. P., W. D. Henner, L. B. Grochow, G. Olsen, S. Edwards, H. Stanbuck, A. Stuart, J. Gockerman, J. Moore, and R. C. Bast. “Clinical and pharmacologic effects of high dose single agent busulfan with autologous bone marrow support in the treatment of solid tumors.” Cancer Res 47, no. 23 (December 1, 1987): 6402–6.
    Link to Item
  - Wallack, M. K., J. A. Bash, E. Leftheriotis, H. Seigler, K. Bland, H. Wanebo, C. Balch, and A. A. Bartolucci. “Positive relationship of clinical and serologic responses to vaccinia melanoma oncolysate.” Arch Surg 122, no. 12 (December 1987): 1460–63. https://doi.org/10.1001/archsurg.1987.01400240108020.
    Full Text Link to Item
  - Slingluff, C. L., T. L. Darrow, and H. F. Seigler. “Human T cells specifically activated against autologous malignant melanoma.” Arch Surg 122, no. 12 (December 1987): 1407–11. https://doi.org/10.1001/archsurg.1987.01400240053009.
    Full Text Link to Item
  - Burton, G. V., E. B. Cox, G. S. Leight, L. R. Prosnitz, J. D. Iglehart, G. A. Olsen, H. F. Seigler, and L. L. Hart. “Inflammatory breast carcinoma. Effective multimodal approach.” Arch Surg 122, no. 11 (November 1987): 1329–32. https://doi.org/10.1001/archsurg.1987.01400230117020.
    Full Text Link to Item
  - Saltz, J., C. E. Buckley, E. Cox, and H. F. Seigler. “The prognostic significance of recall antigen testing in melanoma patients.” Am J Med Sci 294, no. 5 (November 1987): 287–93. https://doi.org/10.1097/00000441-198711000-00001.
    Full Text Link to Item
  - Reintgen, D. S., R. Vollmer, C. Y. Tso, and H. F. Seigler. “Prognosis for recurrent stage I malignant melanoma.” Arch Surg 122, no. 11 (November 1987): 1338–42. https://doi.org/10.1001/archsurg.1987.01400230126022.
    Full Text Link to Item
  - Flowers, J. L., H. F. Seigler, K. S. McCarty, and J. Konrath. “Absence of estrogen receptor in human melanoma as evaluated by a monoclonal antiestrogen receptor antibody.” Arch Dermatol 123, no. 6 (June 1987): 764–65.
    Link to Item
  - Wolfe, W. G., G. V. Burton, H. F. Seigler, I. R. Crocker, and A. L. Vaughn. “Early results with combined modality therapy for carcinoma of the esophagus.” Ann Surg 205, no. 5 (May 1987): 563–71. https://doi.org/10.1097/00000658-198705000-00016.
    Full Text Link to Item
  - Stuhlmiller, G. M., T. L. Darrow, D. M. Haupt, and H. F. Seigler. “Immune response of chimpanzee to purified melanoma 250 kilodalton tumor-associated antigen.” Cancer Immunol Immunother 25, no. 3 (1987): 193–200. https://doi.org/10.1007/BF00199147.
    Full Text Link to Item
  - Perry, M. D., H. F. Seigler, and W. W. Johnston. “Diagnosis of metastatic malignant melanoma by fine needle aspiration biopsy: a clinical and pathologic correlation of 298 cases.” J Natl Cancer Inst 77, no. 5 (November 1986): 1013–21.
    Link to Item
  - MCCARTY, K. S., E. SZABO, J. L. FLOWERS, E. B. COX, G. S. LEIGHT, L. MILLER, J. KONRATH, et al. “USE OF A MONOCLONAL ANTIESTROGEN RECEPTOR ANTIBODY IN THE IMMUNOHISTOCHEMICAL EVALUATION OF HUMAN-TUMORS.” Cancer Research 46, no. 8 (August 1, 1986): 4244–48.
    Link to Item
  - Seigler, H. F. “Investigative studies in the diagnosis and treatment of melanoma.” Invest Radiol 21, no. 7 (July 1986): 596–600. https://doi.org/10.1097/00004424-198607000-00017.
    Full Text Link to Item
  - Caldwell, D. S., G. W. Kernodle, and H. F. Seigler. “Pectoralis pyomyositis: an unusual cause of chest wall pain in a patient with diabetes mellitus and rheumatoid arthritis.” J Rheumatol 13, no. 2 (April 1986): 434–36.
    Link to Item
  - OLSEN, G. A., J. P. GOCKERMAN, B. WALSH, T. WAY, S. AVERY, S. REMINE, C. GILBERT, et al. “HIGH-DOSE BUSULFAN (BU) WITH AUTOLOGOUS BONE-MARROW SUPPORT (ABMS) - A PHASE-I TRIAL.” Proceedings of the American Association for Cancer Research 27 (March 1, 1986): 236–236.
    Link to Item
  - Wallack, M. K., K. R. McNally, E. Leftheriotis, H. Seigler, C. Balch, H. Wanebo, A. A. Bartolucci, and J. A. Bash. “A Southeastern Cancer Study Group phase I/II trial with vaccinia melanoma oncolysates.” Cancer 57, no. 3 (February 1, 1986): 649–55. https://doi.org/10.1002/1097-0142(19860201)57:3<649::aid-cncr2820570342>3.0.co;2-6.
    Full Text Link to Item
  - Bollinger, R. R., C. Miceli, and O. J. Finn. “Monitoring the donor-specific response of renal transplant patients by needle biopsy and long-term culture of alloreactive T-cell clones.” Transplantation Proceedings 18, no. 4 (January 1, 1986): 748–49.
  - Perry, M. D., M. Gore, H. F. Seigler, and W. W. Johnston. “Fine needle aspiration biopsy of metastatic melanoma. A morphologic analysis of 174 cases.” Acta Cytol 30, no. 4 (1986): 385–96.
    Link to Item
  - Fisher, S. R., T. B. Cole, W. C. Meyers, and H. F. Seigler. “Pharyngoesophageal reconstruction using free jejunal interposition grafts.” Arch Otolaryngol 111, no. 11 (November 1985): 747–52. https://doi.org/10.1001/archotol.1985.00800130079010.
    Full Text Link to Item
  - Mahvi, D. M., W. C. Meyers, R. C. Bast, H. F. Seigler, and R. S. Metzgar. “Carcinoma of the pancreas. Therapeutic efficacy as defined by a serodiagnostic test utilizing a monoclonal antibody.” Ann Surg 202, no. 4 (October 1985): 440–45. https://doi.org/10.1097/00000658-198510000-00005.
    Full Text Link to Item
  - Georgiade, G. S., R. Riefkohl, E. Cox, K. S. McCarty, H. F. Seigler, N. G. Georgiade, and J. C. Snowhite. “Long-term clinical outcome of immediate reconstruction after mastectomy.” Plast Reconstr Surg 76, no. 3 (September 1985): 415–20. https://doi.org/10.1097/00006534-198509000-00014.
    Full Text Link to Item
  - Seigler, H. F. “Immunodiagnosis of human malignancy.” Ann Surg 201, no. 4 (April 1985): 415–22. https://doi.org/10.1097/00000658-198504000-00003.
    Full Text Link to Item
  - Reintgen, D. S., K. S. McCarty, R. Vollmer, E. Cox, and H. F. Seigler. “Malignant melanoma and pregnancy.” Cancer 55, no. 6 (March 15, 1985): 1340–44. https://doi.org/10.1002/1097-0142(19850315)55:6<1340::aid-cncr2820550630>3.0.co;2-t.
    Full Text Link to Item
  - Johnston, W. W., M. J. Borowitz, G. M. Stuhlmiller, and H. F. Seigler. “Expression of a melanoma-tumor-associated antigen as demonstrated by a monoclonal antibody (D6.1) in cytopathologic preparations of human tumor cells from effusions and needle aspirates.” Anal Quant Cytol Histol 7, no. 1 (March 1985): 72–80.
    Link to Item
  - MAHVI, D. M., W. C. MEYERS, H. F. SEIGLER, and R. S. METZGAR. “CLINICAL-STUDIES OF A PANCREATIC ONCOFETAL ANTIGEN (DU-PAN-2).” Digestive Diseases and Sciences 30, no. 10 (January 1, 1985): 982–982.
    Link to Item
  - Mahvi, D. M., R. C. Bast, and W. C. Meyers. “Clinical studies of an oncofetal antigen (DU-PAN-2) detected by a monoclonal antibody to pancreatic adenocarcinoma.” Proceedings of the American Association for Cancer Research VOL. 26 (January 1, 1985).
  - PETERS, W. P., J. P. GOCKERMAN, G. A. OLSEN, J. O. MOORE, G. LEIGHT, H. F. SEIGLER, and R. C. BAST. “HIGH-DOSE COMBINATION ALKYLATING AGENT THERAPY WITH AUTOLOGOUS BONE-MARROW SUPPORT AS INITIAL THERAPY FOR METASTATIC BREAST-CANCER.” Breast Cancer Research and Treatment 6, no. 2 (January 1, 1985): 182–182.
    Link to Item
  - Reintgen, D. S., D. E. Paull, H. F. Seigler, E. B. Cox, and K. S. McCarty. “Sex related survival differences in instances of melanoma.” Surg Gynecol Obstet 159, no. 4 (October 1984): 367–72.
    Link to Item
  - Metzgar, R. S., N. Rodriguez, O. J. Finn, M. S. Lan, V. N. Daasch, P. D. Fernsten, W. C. Meyers, W. F. Sindelar, R. S. Sandler, and H. F. Seigler. “Detection of a pancreatic cancer-associated antigen (DU-PAN-2 antigen) in serum and ascites of patients with adenocarcinoma.” Proc Natl Acad Sci U S A 81, no. 16 (August 1984): 5242–46. https://doi.org/10.1073/pnas.81.16.5242.
    Full Text Link to Item
  - Reintgen, D. S., W. Thompson, J. Garbutt, and H. F. Seigler. “Radiologic, endoscopic, and surgical considerations of melanoma metastatic to the gastrointestinal tract.” Surgery 95, no. 6 (June 1984): 635–39.
    Link to Item
  - Akimaru, K., T. Shoji, and H. F. Seigler. “[In vivo evaluation of cellular immunity in melanoma patients against melanoma].” Nihon Geka Gakkai Zasshi 85, no. 2 (February 1984): 93–101.
    Link to Item
  - MCCARTY, K. S., E. COX, G. LEIGHT, G. GEORGIADE, D. L. INGRAM, G. BURTON, and H. F. SEIGLER. “ESTROGEN BINDING IN BREAST-CARCINOMA - REPLY.” Archives of Pathology & Laboratory Medicine 108, no. 10 (January 1, 1984): 772–73.
    Link to Item
  - REINTGEN, D. S., E. COX, R. VOLLMER, K. S. MCCARTY, and H. F. SEIGLER. “PROGNOSTIC MODEL FOR STAGE-1 CUTANEOUS MELANOMA BASED ON HISTOLOGIC AND CLINICAL-VARIABLES.” Laboratory Investigation 50, no. 1 (January 1, 1984): A48–A48.
    Link to Item
  - Stuhlmiller, G. M., M. J. Borowitz, and H. F. Seigler. “D6.1, a murine antimelanoma monoclonal antibody from congenitally athymic nude mice immunized with purified melanoma tumor-associated antigen.” Hybridoma 3, no. 4 (1984): 333–46. https://doi.org/10.1089/hyb.1984.3.333.
    Full Text Link to Item
  - Reintgen, D. S., W. Thompson, J. Garbutt, and H. F. Seigler. “Radiologic, endoscopic and surgical considerations of malignant melanoma metastatic to the small intestine.” Curr Surg 41, no. 2 (1984): 87–89.
    Link to Item
  - Silverman, P. M., D. K. Heaston, M. Korobkin, and H. F. Seigler. “Computed tomography in the detection of abdominal metastases from malignant melanoma.” Invest Radiol 19, no. 4 (1984): 309–12. https://doi.org/10.1097/00004424-198407000-00013.
    Full Text Link to Item
  - Reintgen, D. S., D. Sullivan, E. Coleman, W. Briner, B. P. Croker, and H. F. Seigler. “Lymphoscintigraphy for malignant melanoma. Surgical considerations.” Am Surg 49, no. 12 (December 1983): 672–78.
    Link to Item
  - Gussack, G. S., D. Reintgen, E. Cox, S. R. Fisher, T. B. Cole, and H. F. Seigler. “Cutaneous melanoma of the head and neck. A review of 399 cases.” Arch Otolaryngol 109, no. 12 (December 1983): 803–8. https://doi.org/10.1001/archotol.1983.00800260025006.
    Full Text Link to Item
  - Reintgen, D. S., E. B. Cox, K. S. McCarty, R. T. Vollmer, and H. F. Seigler. “Efficacy of elective lymph node dissection in patients with intermediate thickness primary melanoma.” Ann Surg 198, no. 3 (September 1983): 379–85. https://doi.org/10.1097/00000658-198309000-00014.
    Full Text Link to Item
  - Heaston, D. K., C. E. Putman, B. A. Rodan, E. Nicholson, C. E. Ravin, M. Korobkin, J. T. Chen, and H. F. Seigler. “Solitary pulmonary metastases in high-risk melanoma patients: a prospective comparison of conventional and computed tomography.” Ajr Am J Roentgenol 141, no. 1 (July 1983): 169–74. https://doi.org/10.2214/ajr.141.1.169.
    Full Text Link to Item
  - Reintgen, D. S., B. Croker, C. Verveart, and H. F. Seigler. “Functional and morphologic changes associated with insulinoma transplantation into diabetic rats.” Am J Pathol 112, no. 1 (July 1983): 1–6.
    Link to Item
  - Reintgen, D. S., K. Shimizu, E. Coleman, W. Briner, J. Kitzmiller, G. Eisenbarth, and H. F. Seigler. “Immunodiagnosis of tumors in vivo using radiolabeled monoclonal antibody A2B5.” J Surg Oncol 23, no. 3 (July 1983): 205–11. https://doi.org/10.1002/jso.2930230318.
    Full Text Link to Item
  - Silverman, P. M., D. K. Heaston, M. Korobkin, and H. F. Seigler. “COMPUTED TOMOGRAPHY (CT) OF ABDOMINAL METASTASIS FROM MALIGNANT MELANOMA.” Investigative Radiology 18, no. 4 (July 1983): S24–S24. https://doi.org/10.1097/00004424-198307000-00116.
    Full Text
  - Fisher, S. R., T. B. Cole, and H. F. Seigler. “Application of posterior neck dissection in treating malignant melanoma of the posterior scalp.” Laryngoscope 93, no. 6 (June 1983): 760–65. https://doi.org/10.1288/00005537-198306000-00012.
    Full Text Link to Item
  - Feldman, J. M., C. A. Castleberry, C. Vervaert, and H. F. Seigler. “Comparison of monoamine oxidase in golden hamster islets and insulinoma.” Res Commun Chem Pathol Pharmacol 40, no. 2 (May 1983): 307–20.
    Link to Item
  - Reintgen, D., and H. F. Seigler. “In Reply.” Jama: The Journal of the American Medical Association 249, no. 11 (March 18, 1983): 1438. https://doi.org/10.1001/jama.1983.03330350019017.
    Full Text
  - Reintgen, D. S., K. S. McCarty, B. Woodard, E. Cox, and H. F. Seigler. “Metastatic malignant melanoma with an unknown primary.” Surg Gynecol Obstet 156, no. 3 (March 1983): 335–40.
    Link to Item
  - Cance, W. G., C. Vervaert, and H. F. Seigler. “Transplantation of rat insulinoma allografts with cyclosporin A.” Surgery 93, no. 2 (February 1983): 279–88.
    Link to Item
  - FERGUSON, B. J., R. VOLLMER, D. REINTGEN, D. E. PAULL, H. F. SEIGLER, E. B. COX, and K. S. MCCARTY. “HISTOLOGIC-STUDY OF PARAMETERS INFLUENCING SEX-DIFFERENCES IN SURVIVAL FOR PATIENTS WITH MELANOMA.” Laboratory Investigation 48, no. 1 (January 1, 1983): A24–A24.
    Link to Item
  - REINTGEN, D. S., N. J. PICKETT, V. S. LUCAS, A. T. HUANG, and H. F. SEIGLER. “CLINICAL-TRIAL OF DTIC, CCNU, BLEOMYCIN, AND VINCRISTINE (BOLD) CHEMOTHERAPY FOR METASTATIC MELANOMA.” Proceedings of the American Association for Cancer Research 24, no. MAR (January 1, 1983): 143–143.
    Link to Item
  - Shimizu, K., D. Reintgen, R. Rowley, E. Coleman, W. Briner, H. Seigler, and G. S. Eisenbarth. “In vivo and in vitro binding of iodinated monoclonal antibody A2B5 to RIN insulinoma cells.” Hybridoma 2, no. 1 (1983): 69–77. https://doi.org/10.1089/hyb.1983.2.69.
    Full Text Link to Item
  - Reintgen, D. S., K. S. McCarty, E. Cox, and H. F. Seigler. “Malignant melanoma in the American black.” Curr Surg 40, no. 3 (1983): 215–17.
    Link to Item
  - Reintgen, D. S., K. M. McCarty, E. Cox, and H. F. Seigler. “Malignant melanoma in black American and white American populations. A comparative review.” Jama 248, no. 15 (October 15, 1982): 1856–59.
    Link to Item
  - McCarty, K. S., R. Sasso, D. Budwit, G. S. Georgiade, and H. F. Seigler. “Immunoglobulin localization in the normal human mammary gland: variation with the menstrual cycle.” Am J Pathol 107, no. 3 (June 1982): 322–26.
    Link to Item
  - Morzycka, M., B. P. Croker, H. F. Siegler, and C. C. Tisher. “Evaluation of recurrent glomerulonephritis in kidney allografts.” Am J Med 72, no. 4 (April 1982): 588–98. https://doi.org/10.1016/0002-9343(82)90453-3.
    Full Text Link to Item
  - BUDWIT, D. A., R. SASSO, H. F. SEIGLER, N. G. GEORGIADE, and K. S. MCCARTY. “IMMUNOGLOBULIN LOCALIZATION IN THE NORMAL HUMAN MAMMARY-GLAND - VARIATION WITH THE MENSTRUAL-CYCLE.” Laboratory Investigation 46, no. 1 (January 1, 1982): A11–A11.
    Link to Item
  - Georgiade, G., N. Georgiade, K. S. McCarty, and H. F. Seigler. “Rationale for immediate reconstruction of the breast following modified radical mastectomy.” Ann Plast Surg 8, no. 1 (January 1982): 20–28. https://doi.org/10.1097/00000637-198201000-00006.
    Full Text Link to Item
  - McCarty, K. S., D. E. Nichols, and G. Leight. “Comparison of clinical response to hormone therapy using estrogen receptor analyses by biochemical versus histochemical methods.” Laboratory Investigation 46, no. 1 (January 1, 1982).
  - REINTGEN, D., K. SHIMIZU, E. COLEMAN, G. S. EISENBARTH, W. BRINER, and H. F. SEIGLER. “INVIVO TUMOR-LOCALIZATION USING RADIOLABELED MONOCLONAL ANTIBODY-A2B5.” Surgical Forum 33 (January 1, 1982): 431–34.
    Link to Item
  - Stuhlmiller, G. M., M. J. Borowitz, B. P. Croker, and H. F. Seigler. “Multiple assay characterization of murine monoclonal antimelanoma antibodies.” Hybridoma 1, no. 4 (1982): 447–60. https://doi.org/10.1089/hyb.1.1982.1.447.
    Full Text Link to Item
  - Stuhlmiller, G. M., D. C. Sullivan, C. E. Vervaert, B. P. Croker, C. C. Harris, and H. F. Seigler. “In vivo tumor localization using tumor-specific monkey xenoantibody, alloantibody, and murine monoclonal xenoantibody.” Ann Surg 194, no. 5 (November 1981): 592–601. https://doi.org/10.1097/00000658-198111000-00007.
    Full Text Link to Item
  - Sullivan, D. C., B. P. Croker, C. C. Harris, P. Deery, and H. F. Seigler. “Lymphoscintigraphy in malignant melanoma: 99mTc antimony sulfur colloid.” Ajr Am J Roentgenol 137, no. 4 (October 1981): 847–51. https://doi.org/10.2214/ajr.137.4.847.
    Full Text Link to Item
  - Mutzner, P. A., G. M. Stuhlmiller, H. F. Seigler, W. E. Stumpf, and M. Sar. “[Basis for a specific-active immunotherapy in malignant melanoma].” Schweiz Med Wochenschr 111, no. 36 (September 5, 1981): 1322–25.
    Link to Item
  - Akimaru, K., G. M. Stuhlmiller, and H. F. Seigler. “Allotransplantation of insulinoma into the testis of diabetic rats.” Transplantation 32, no. 3 (September 1981): 227–32. https://doi.org/10.1097/00007890-198109000-00009.
    Full Text Link to Item
  - Thompson, W. M., W. C. Meyers, J. B. Hanks, H. F. Seigler, R. Postlethwait, R. S. Jones, O. K. Akwari, and T. B. Cole. “FUNCTION OF JEJUNAL AUTOTRANSPLANTS FOR REPLACEMENT OF THE CERVICAL ESOPHAGUS.” Investigative Radiology 16, no. 5 (September 1981): 399–399. https://doi.org/10.1097/00004424-198109000-00078.
    Full Text
  - Chen, J. T., N. S. Dahmash, C. E. Ravin, D. K. Heaston, C. E. Putman, H. F. Seigler, and J. C. Reed. “Metastatic melanoma in the thorax: report of 130 patients.” Ajr Am J Roentgenol 137, no. 2 (August 1981): 293–98. https://doi.org/10.2214/ajr.137.2.293.
    Full Text Link to Item
  - McCarty, K. S., J. W. Grant, N. Georgiade, W. Wilkinson, R. Graham, B. J. Ferguson, D. Deubner, and H. F. Seigler. “Immunoglobulin localization in benign and malignant lesions of the human mammary gland.” Cancer 48, no. 1 (July 1, 1981): 69–75. https://doi.org/10.1002/1097-0142(19810701)48:1<69::aid-cncr2820480115>3.0.co;2-m.
    Full Text Link to Item
  - Georgiade, G. S., N. G. Georgiade, K. S. McCarty, B. J. Ferguson, and H. F. Seigler. “Modified radical mastectomy with immediate reconstruction for carcinoma of the breast.” Ann Surg 193, no. 5 (May 1981): 565–73. https://doi.org/10.1097/00000658-198105000-00005.
    Full Text Link to Item
  - Reintgen, D., W. G. Wolfe, S. Osofsky, and H. F. Seigler. “Renal artery stenosis in children.” J Pediatr Surg 16, no. 1 (February 1981): 26–31. https://doi.org/10.1016/s0022-3468(81)80110-8.
    Full Text Link to Item
  - Feldman, J. M., C. Vervaert, C. Klatt, and H. F. Seigler. “Therapy of malignant hamster insulinomas with monoamine precursors.” Diabetologia 20, no. 2 (February 1981): 148–54. https://doi.org/10.1007/BF00262019.
    Full Text Link to Item
  - CROKER, B. P., M. MORZYCKA, H. F. SEIGLER, and C. C. TISHER. “RECURRENT GLOMERULONEPHRITIS-(GN) IN TRANSPLANTS.” Kidney International 19, no. 1 (January 1, 1981): 265–265.
    Link to Item
  - LEVINE, S. J., M. T. GAILLARD, H. F. SEIGLER, and R. S. METZGAR. “CHARACTERIZATION OF MONOCLONAL-ANTIBODIES TOHUMAN PANCREATIC TUMOR-CELLS.” Proceedings of the American Association for Cancer Research 22, no. MAR (January 1, 1981): 301–301.
    Link to Item
  - PAULL, D. E., H. F. SEIGLER, E. B. COX, and K. S. MCCARTY. “FACTORS INFLUENCING SEX-DIFFERENCES IN SURVIVAL FOR PATIENTS WITH MELANOMA.” Proceedings of the American Association for Cancer Research 22, no. MAR (January 1, 1981): 163–163.
    Link to Item
  - Akimaru, K., G. M. Stuhlmiller, and H. F. Seigler. “In vivo evaluation of cell mediated immunity against human melanoma.” J Surg Oncol 17, no. 3 (1981): 263–78. https://doi.org/10.1002/jso.2930170309.
    Full Text Link to Item
  - Akimaru, K., G. M. Stuhlmiller, and H. F. Seigler. “Human melanoma growth in the peritoneal cavity of the athymic mouse--a model for in vivo study of cell-mediated immunity.” J Surg Oncol 17, no. 4 (1981): 309–20. https://doi.org/10.1002/jso.2930170403.
    Full Text Link to Item
  - Akimaru, K., G. M. Stuhlmiller, and H. F. Seigler. “Influence of mouse hepatitis virus on the growth of human melanoma in the peritoneal cavity of the athymic mouse.” J Surg Oncol 17, no. 4 (1981): 327–39. https://doi.org/10.1002/jso.2930170405.
    Full Text Link to Item
  - Bullard, D. E., E. B. Cox, and H. F. Seigler. “Central nervous system metastases in malignant melanoma.” Neurosurgery 8, no. 1 (January 1981): 26–30. https://doi.org/10.1227/00006123-198101000-00006.
    Full Text
  - McCarty, K. S., D. S. Reintgen, and H. F. Seigler. “Cytochemistry of sex steroid receptors: a critique.” Breast Cancer Res Treat 1, no. 4 (1981): 315–25. https://doi.org/10.1007/BF01806747.
    Full Text Link to Item
  - McCook, T. A., S. R. Mills, D. R. Kirks, D. K. Heaston, H. F. Seigler, R. B. Malone, and S. G. Osofsky. “Percutaneous transluminal renal artery angioplasty in a 3 1/2-year-old hypertensive girl.” J Pediatr 97, no. 6 (December 1980): 958–60. https://doi.org/10.1016/s0022-3476(80)80434-3.
    Full Text Link to Item
  - Seigler, H. F., V. S. Lucas, N. J. Pickett, and A. T. Huang. “DTIC, CCNU, bleomycin and vincristine (BOLD) in metastatic melanoma.” Cancer 46, no. 11 (December 1, 1980): 2346–48. https://doi.org/10.1002/1097-0142(19801201)46:11<2346::aid-cncr2820461104>3.0.co;2-6.
    Full Text Link to Item
  - McCarty, K. S., J. Wortman, S. Stowers, D. B. Lubahn, and H. F. Seigler. “Sex steroid receptor analysis in human melanoma.” Cancer 46, no. 6 (September 15, 1980): 1463–70. https://doi.org/10.1002/1097-0142(19800915)46:6<1463::aid-cncr2820460628>3.0.co;2-q.
    Full Text Link to Item
  - Reintgen, D., B. Croker, C. Vervaert, J. Feldman, and H. F. Seigler. “Immunological consequences of transplanting rat insulinomas.” Transplantation 30, no. 1 (July 1980): 16–22. https://doi.org/10.1097/00007890-198007000-00004.
    Full Text Link to Item
  - Copeland, D. D., J. D. Sink, and H. F. Seigler. “Primary intracranial melanoma presenting as a suprasellar tumor.” Neurosurgery 6, no. 5 (May 1980): 542–45. https://doi.org/10.1227/00006123-198005000-00008.
    Full Text
  - McCarty, K. S., G. H. Kesterson, T. K. Barton, H. F. Seigler, and N. G. Georgiade. “Selection of patients for heterotopic implantation of the areola and nipple.” Surg Gynecol Obstet 150, no. 4 (April 1980): 545–47.
    Link to Item
  - COX, E., W. W. SHINGLETON, J. MARTELL, E. NICHOLSOR, and H. F. SEIGLER. “SPECIFIC ACTIVE IMMUNIZATION IN MELANOMA - PROGNOSTIC FACTORS.” Proceedings of the American Association for Cancer Research 21, no. MAR (January 1, 1980): 131–131.
    Link to Item
  - MOSSLER, J. A., S. STOWERS, D. LUBAHN, H. F. SEIGLER, K. S. MCCARTY, and J. LASZLO. “COMPARATIVE-ANALYSIS OF SEX STEROID BINDING IN HUMAN-MELANOMA.” Proceedings of the American Association for Cancer Research 21, no. MAR (January 1, 1980): 476–476.
    Link to Item
  - Meyers, W. C., H. F. Seigler, J. B. Hanks, W. M. Thompson, R. Postlethwait, R. S. Jones, O. K. Akwari, and T. B. Cole. “Postoperative function of "free" jejunal transplants for replacement of the cervical esophagus.” Ann Surg 192, no. 4 (1980): 439–50. https://doi.org/10.1097/00000658-198010000-00002.
    Full Text Link to Item
  - Reintgen, D., J. Feldman, C. Vervaert, and H. F. Seigler. “Transplantation of insulinoma into the diabetic Syrian hamster.” Ann Surg 191, no. 1 (January 1980): 105–13. https://doi.org/10.1097/00000658-198001000-00019.
    Full Text Link to Item
  - SEIGLER, H. F., C. VERVAERT, and G. STUHLMILLER. “SPECIFIC ISOTOPIC SCAN LOCALIZATION OF HUMAN-MELANOMA USING IODINATED MONOSPECIFIC ANTIBODY.” Proceedings of the American Association for Cancer Research 21, no. MAR (January 1, 1980): 200–200.
    Link to Item
  - Seigler, H. F. “Melanoma.” Adv Surg 14 (1980): 231–57.
    Link to Item
  - Mutzner, P. A., G. M. Stuhlmiller, and H. F. Seigler. “Characterization of melanoma cell membrane tumor-associated antigens using xenoserum, alloserum, and autoserum: I. immunofluorescence.” J Surg Oncol 14, no. 4 (1980): 367–77. https://doi.org/10.1002/jso.2930140411.
    Full Text Link to Item
  - Kesterson, G. H., N. Georgiade, H. F. Seigler, T. K. Barton, and K. S. McCarty. “Cystosarcoma phylloides. A steroid receptor and ultrastructure analysis.” Ann Surg 190, no. 5 (November 1979): 640–47. https://doi.org/10.1097/00000658-197911000-00014.
    Full Text Link to Item
  - Feldman, J. M., D. S. Reintgen, and H. F. Seigler. “Monoamine oxidase and catechol-O-methyltransferase activity in hamster and rat insulinomas.” Diabetologia 17, no. 4 (October 1979): 249–56. https://doi.org/10.1007/BF01235862.
    Full Text Link to Item
  - Meyers, W. C., N. Harris, S. Stein, M. Brooks, R. S. Jones, W. M. Thompson, D. L. Stickel, and H. F. Seigler. “Alimentary tract complications after renal transplantation.” Ann Surg 190, no. 4 (October 1979): 535–42. https://doi.org/10.1097/00000658-197910000-00013.
    Full Text Link to Item
  - Seigler, H. F., E. Cox, F. Mutzner, L. Shepherd, E. Nicholson, and W. W. Shingleton. “Specific active immunotherapy for melanoma.” Ann Surg 190, no. 3 (September 1979): 366–72. https://doi.org/10.1097/00000658-197909000-00012.
    Full Text Link to Item
  - Ruderman, R. J., G. G. Poehling, R. Gray, M. Nardone, W. Goodman, and H. F. Seigler. “Orthopedic complications of renal transplantation in children.” Transplant Proc 11, no. 1 (March 1979): 104–6.
    Link to Item
  - SEIGLER, H. F., V. S. LUCAS, N. J. PICKETT, and A. T. HUANG. “PHASE-II STUDY OF BLEOMYCIN, ONCOVIN LOMUSTINE AND DTIC (BOLD) IN STAGE-IV METASTATIC MELANOMA.” Proceedings of the American Association for Cancer Research 20, no. MAR (January 1, 1979): 427–427.
    Link to Item
  - Seigler, H. F., V. S. Lucas, N. J. Pickett, and A. T. Huang. “A phase II study of bleomycin, oncovin, lomustine and DTIC (BOLD) in stage IV metastatic melanoma.” Proceedings of the American Association for Cancer Research Vol. 20 (1979): No.C-566.
  - Seigler, H. F., V. S. Lucas, N. J. Pickett, and A. T. Huang. “A phase II study of bleomycin, oncovin, lomustine and DTIC (BOLD) in stage IV metastatic melanoma.” Proceedings of the American Association for Cancer Research Vol. 20 (January 1, 1979).
  - Avent, J., C. Vervaert, and H. F. Seigler. “Non-specific and specific active immunotherapy in a B16 murine melanoma system.” J Surg Oncol 12, no. 1 (1979): 87–96. https://doi.org/10.1002/jso.2930120111.
    Full Text Link to Item
  - Oddson, T. A., R. P. Rice, H. F. Seigler, W. M. Thompson, F. M. Kelvin, and W. M. Clark. “The spectrum of small bowel melanoma.” Gastrointestinal Radiology 3, no. 4 (October 1, 1978): 419–23.
  - Oddson, T. A., R. P. Rice, H. F. Seigler, W. M. Thompson, F. M. Kelvin, and W. M. Clark. “The spectrum of small bowel melanoma.” Gastrointest Radiol 3, no. 4 (October 1, 1978): 419–23. https://doi.org/10.1007/BF01887106.
    Full Text Link to Item
  - Thompson, W. M., W. Meyers, H. F. Seigler, and R. P. Rice. “Gastrointestinal complications of renal transplantation.” Semin Roentgenol 13, no. 4 (October 1978): 319–28. https://doi.org/10.1016/0037-198x(78)90018-4.
    Full Text Link to Item
  - Ward, F. E., N. R. Mendell, H. F. Seigler, J. M. MacQueen, and D. B. Amos. “Factors which have a significant effect on the survival of human skin grafts.” Transplantation 26, no. 3 (September 1978): 194–98. https://doi.org/10.1097/00007890-197809000-00014.
    Full Text Link to Item
  - Harrison, L. H., M. W. Flye, and H. F. Seigler. “Incidence of anatomical variants in renal vasculature in the presence of normal renal function.” Ann Surg 188, no. 1 (July 1978): 83–89. https://doi.org/10.1097/00000658-197807000-00014.
    Full Text Link to Item
  - Sink, J. D., S. A. Kramer, D. D. Copeland, and H. F. Seigler. “Cloacogenic carcinoma.” Ann Surg 188, no. 1 (July 1978): 53–59. https://doi.org/10.1097/00000658-197807000-00009.
    Full Text Link to Item
  - Stewart, W. R., R. H. Gelberman, J. M. Harrelson, and H. F. Seigler. “Skeletal metastases of melanoma.” J Bone Joint Surg Am 60, no. 5 (July 1978): 645–49.
    Link to Item
  - Stuhlmiller, G. M., R. W. Green, and H. F. Seigler. “Solubilization and partial isolation of human melanoma tumor-associated antigens.” J Natl Cancer Inst 61, no. 1 (July 1978): 61–67. https://doi.org/10.1093/jnci/61.1.61.
    Full Text Link to Item
  - Hemstreet, G. P., J. R. Dawson, and H. F. Seigler. “Tumor membrane lymphocyte stimulation assay in patients with renal cell carcinoma.” Cancer Res 38, no. 5 (May 1978): 1447–56.
    Link to Item
  - Runge, P. M., J. N. Schwartz, H. F. Seigler, B. H. Woodard, and J. D. Shelburne. “Gallbladder with ectopic gastric mucosa: ultrastructural analysis.” Arch Pathol Lab Med 102, no. 4 (April 1978): 209–11.
    Link to Item
  - STUHLMILLER, G. M., R. W. GREEN, and H. F. SEIGLER. “PARTIAL ISOLATION OF HUMAN MELANOMA TUMOR ASSOCIATED ANTIGENS.” Proceedings of the American Association for Cancer Research 19, no. MAR (January 1, 1978): 12–12.
    Link to Item
  - Seigler, H. F. “Invited commentary.” World Journal of Surgery 1, no. 5 (September 1, 1977): 553–54. https://doi.org/10.1007/BF01556180.
    Full Text
  - Seigler, H. F., and B. F. Fetter. “Current management of melanoma.” Ann Surg 186, no. 1 (July 1977): 1–12. https://doi.org/10.1097/00000658-197707000-00001.
    Full Text Link to Item
  - Stuhlmiller, G. M., J. A. Boylston, H. F. Seigler, and B. F. Fetter. “Immunodiagnosis of melanoma using chimpanzee antihuman melanoma antiserum.” Am J Clin Pathol 67, no. 6 (June 1977): 573–79. https://doi.org/10.1093/ajcp/67.6.573.
    Full Text Link to Item
  - Seigler, H. F., F. E. Ward, R. E. McCoy, J. L. Weinerth, J. C. Gunnells, and D. L. Stickel. “Long-term results with forty-five living related renal allograft recipients genotypically identical for HLA.” Surgery 81, no. 3 (March 1977): 274–83.
    Link to Item
  - Stuhlmiller, G. M., and H. F. Seigler. “Enzymatic susceptibility and spontaneous release of human melanoma tumor-associated antigens.” J Natl Cancer Inst 58, no. 2 (February 1977): 215–21. https://doi.org/10.1093/jnci/58.2.215.
    Full Text Link to Item
  - BUCKLEY, C. E., D. H. WHITE, and H. F. SEIGLER. “HLA-B7 ASSOCIATED TUBERCULIN HYPORESPONSIVENESS IN BCG TREATED PATIENTS.” Clinical Research 25, no. 1 (January 1, 1977): A53–A53.
    Link to Item
  - Buckley, C. E., D. H. White, and H. F. Seigler. “HLA-B7 associated tuberculin hyporesponsiveness in BCG treated patients.” American Review of Respiratory Disease 115, no. 4 II (January 1, 1977): 48.
  - Snyderman, R., H. F. Seigler, and L. Meadows. “Abnormalitieis of monocyte chemotaxis in patients with melanoma: effects of immunotherapy and tumor removal.” J Natl Cancer Inst 58, no. 1 (January 1977): 37–41. https://doi.org/10.1093/jnci/58.1.37.
    Full Text Link to Item
  - Buckley, C. E., D. H. White, and H. F. Seigler. “HLA-B7 associated tuberculin hyporesponsiveness in BCG treated melanoma patients.” Monogr Allergy 11 (1977): 97–105.
    Link to Item
  - Kilpatrick, R. J., and H. F. Seigler. “Specific cytotoxic antibody in the sera of patients with melanoma.” J Surg Res 21, no. 5 (November 1976): 301–5. https://doi.org/10.1016/0022-4804(76)90041-x.
    Full Text Link to Item
  - Woodhall, P. B., R. C. McCoy, J. C. Gunnells, and H. F. Seigler. “Apparent recurrence of progressive systemic sclerosis in a renal allograft.” Jama 236, no. 9 (August 30, 1976): 1032–34.
    Link to Item
  - Lober, C. W., H. F. Seigler, and A. Spock. “Cystic fibrosis in a black woman.” Jama 235, no. 11 (March 15, 1976): 1140–41.
    Link to Item
  - Seigler, H. F., F. E. Ward, R. C. McCoy, J. C. Gunnells, R. A. Gutman, C. C. Tisher, J. L. Weinerth, and D. L. Stickel. “Renal transplantation between HL-A haploidentical donor-recipient pairs: functional and morphological evaluation.” Surgery 79, no. 3 (March 1976): 241–47.
    Link to Item
  - STUHLMILLER, G., and H. F. SEIGLER. “ENZYMATIC SUSCEPTIBILITY AND PARTIAL ISOLATION OF A MELANOMA ASSOCIATED ANTIGEN.” Proceedings of the American Association for Cancer Research 17, no. MAR (January 1, 1976): 213–213.
    Link to Item
  - Seigler, H., C. E. Buckley, L. B. Sheppard, B. J. Horne, and W. W. Shingleton. “Adoptive transfer and specific active immunization of patients with malignant melanoma.” Ann N Y Acad Sci 277, no. 00 (1976): 522–32. https://doi.org/10.1111/j.1749-6632.1976.tb41726.x.
    Full Text Link to Item
  - Stuhlmiller, G. M., T. Mohanakumar, R. S. Metzgar, and H. F. Seigler. “The use of non-human primates for production of antisera to human tumor-associated antigens.” J Immunol Methods 12, no. 3–4 (1976): 267–74. https://doi.org/10.1016/0022-1759(76)90048-x.
    Full Text Link to Item
  - Mills, S. A., H. F. Seigler, and W. G. Wolfe. “The incidence and management of pulmonary mycosis in renal allograft patients.” Ann Surg 182, no. 5 (November 1975): 617–26. https://doi.org/10.1097/00000658-197511000-00014.
    Full Text Link to Item
  - Thompson, W. M., H. F. Seigler, and R. P. Rice. “Ileocolonic perforation. A complication following renal transplantation.” Am J Roentgenol Radium Ther Nucl Med 125, no. 3 (November 1975): 723–30. https://doi.org/10.2214/ajr.125.3.723.
    Full Text Link to Item
  - Stuhlmiller, G. M., and H. F. Seigler. “Characterization of a chimpanzee anti-human melanoma antiserum.” Cancer Res 35, no. 8 (August 1975): 2132–37.
    Link to Item
  - McCoy, R., J. Clapp, and H. F. Seigler. “Membranoproliferative glomerulonephritis. Progression from the pure form to the crescentic form with recurrence after transplantation.” Am J Med 59, no. 2 (August 1975): 288–92. https://doi.org/10.1016/0002-9343(75)90366-6.
    Full Text Link to Item
  - Seigler, H. F., R. S. Metzgar, T. Mohanakumar, and G. M. Stuhlmiller. “Human melanoma and leukemia associated antigens difined by nonhuman primate antisera.” Fed Proc 34, no. 8 (July 1975): 1642–46.
    Link to Item
  - Shingleton, W. W., H. F. Seigler, L. H. Stocks, and R. W. Downs. “Management of recurrent melanoma of the extremity.” Cancer 35, no. 3 (March 1975): 574–79. https://doi.org/10.1002/1097-0142(197503)35:3<574::aid-cncr2820350303>3.0.co;2-5.
    Full Text Link to Item
  - Seigler, H. F., W. W. Shingleton, and K. L. Pickrell. “Intralesional BCG, intravenous immune lymphocytes, and immunization with neuraminidase-treated tumor cells to manage melanoma; A clinical assessment.” Plast Reconstr Surg 55, no. 3 (March 1975): 294–98.
    Link to Item
  - GILBERTSEN, R. B., H. F. SEIGLER, and R. S. METZGAR. “IMMUNE COMPETENCE OF CHIMPANZEES FOLLOWING THYMECTOMY, SPLENECTOMY, AND X-IRRADIATION.” Federation Proceedings 34, no. 3 (January 1, 1975): 1022–1022.
    Link to Item
  - Gilbertsen, R. B., H. F. Seigler, and R. S. Metzgar. “Immune competence of chimpanzees following thymectomy, splenectomy, and X irradiation.” Federation Proceedings 34, no. 3 (January 1, 1975).
  - Seigler, H. F., W. W. Shingleton, B. J. Horne, and K. L. Pickrell. “The use of BCG, adoptive transfer, and neuraminidase treated tumor cells in the management of melanoma.” Behring Inst.Mitt. No. 56 (January 1, 1975): 214–23.
  - Shingleton, W. W., and H. F. Seigler. “Management of recurrent melanoma of the extremity.” Excerpta Medica, Ics No. 354 vol.6 (1975): 103–6.
  - Levy, N. L., H. F. Seigler, and W. W. Shingleton. “A multiphase immunotherapy regimen for human melanoma: clinical and laboratory results.” Cancer 34, no. 4 Suppl (October 1974): suppl:1548-57. https://doi.org/10.1002/1097-0142(197410)34:8+<1548::aid-cncr2820340829>3.0.co;2-t.
    Full Text Link to Item
  - Gilbertsen, R. B., R. S. Metzgar, and H. F. Seigler. “Immunologic studies on T and B lymphocytes in chimpanzees: effects of thymectomy and irradiation.” Transplant Proc 6, no. 2 (June 1974): 183–88.
    Link to Item
  - Seigler, H. F., F. E. Ward, R. S. Metzgar, S. M. Stulting, M. B. Phaup, and B. J. Adams. “Mixed-lymphocyte-culture responses in chimpanzee families.” Transplant Proc 6, no. 2 (June 1974): 135–39.
    Link to Item
  - Ward, F. E., H. F. Seigler, R. S. Metzgar, D. M. Reid, E. D. Hill, and C. E. Guthrie. “Histocompatibility testing in chimpanzee families.” Transplant Proc 6, no. 2 (June 1974): 129–34.
    Link to Item
  - Ward, F. E., H. F. Seigler, and R. S. Metzgar. “Summary of the proceedings of the second international workshop on transplantation genetics of nonhuman primates.” Transplant Proc 6, no. 2 (June 1974): 223–27.
    Link to Item
  - Seigler, H. F., F. E. Ward, R. S. Metzgar, and S. M. Stulting. “Histocompatibility testing and mixed lymphocyte culture responses in chimpanzee families.” Transplantation 17, no. 3 (March 1974): 265–71. https://doi.org/10.1097/00007890-197403000-00005.
    Full Text Link to Item
  - Gonzales, E. T., J. H. Grimes, H. F. Seigler, and W. G. Young. “Renal artery aneurysm in a solitary kidney: successful surgical repair.” South Med J 67, no. 3 (March 1974): 368–70. https://doi.org/10.1097/00007611-197403000-00034.
    Full Text Link to Item
  - Seigler, H. F., W. W. Shingleton, R. S. Metzgar, and C. E. Buckley. “Immune responsiveness and immunotherapy in patients with metastatic melanoma.” Bol.Asoc.Med.P.R. 66, no. 7 (January 1, 1974): 129–31.
  - Seigler, H. F., F. E. Ward, D. B. Amos, and D. L. Stickel. “The immunogenetics of the major histocompatibility chromosomal region in man.” Surgery 74, no. 2 (August 1973): 190–97.
    Link to Item
  - Yunis, E. J., H. F. Seigler, R. L. Simmons, and D. B. Amos. “HL A typing, mixed leukocyte reactivity, and skin graft survival in a family with a recombinant at the HL-1 chromosomal region (major transplantation region).” Transplantation 15, no. 5 (May 1973): 435–40.
    Link to Item
  - MacDonell, R. C., J. H. Patterson, G. T. Zwiren, H. F. Seigler, R. S. Metzgar, D. B. Caplan, J. J. Corrigan, J. W. Bland, P. A. Ahmann, and B. L. Behrens. “Cross circulation between children in hepatic coma and chimpanzees. Clinical, biochemical, and coagulation observations.” J Pediatr 82, no. 4 (April 1973): 591–97. https://doi.org/10.1016/s0022-3476(73)80583-9.
    Full Text Link to Item
  - Metzgar, R. S., P. M. Bergoc, M. A. Moreno, and H. F. Seigler. “Brief communication: melanoma-specific antibodies produced in monkeys by immunization with human melanoma cell lines.” J Natl Cancer Inst 50, no. 4 (April 1973): 1065–68. https://doi.org/10.1093/jnci/50.4.1065.
    Full Text Link to Item
  - Ward, F. E., and H. F. Seigler. “Mixed lymphocyte reactions and skin graft survival in an HL-A recombinant family.” Transplant Proc 5, no. 1 (March 1973): 359–62.
    Link to Item
  - Ward, F. E., H. F. Seigler, R. S. Metzgar, and D. M. Reid. “Cross-reactivity of primate alloantigens: absorption of anti-HL-A reactivity from human alloantisera by chimpanzee lymphocytes.” Tissue Antigens 3, no. 5 (1973): 389–401. https://doi.org/10.1111/j.1399-0039.1973.tb00509.x.
    Full Text Link to Item
  - Yunis, E. J., H. F. Seigler, R. L. Simmons, and D. B. Amos. “Hl-a typing, mixed leukocyte reactivity, and skin graft survival in a family with a recombinant at the hl-1 chromosomal region (Major transplantation region).” Transplantation 11, no. 5 (January 1, 1973): 435–40. https://doi.org/10.1097/00007890-197311050-00003.
    Full Text
  - Stickel, D. L., H. F. Seigler, N. L. Harris, and M. F. Ross. “The rehabilitation of renal allograft recipients.” Transplant Proc 4, no. 4 (December 1972): 755–57.
    Link to Item
  - Seigler, H. F., D. L. Stickel, J. C. Gunnells, R. McCoy, F. E. Ward, E. E. Anderson, and D. B. Amos. “Renal transplantation between histocompatible donor-recipient pairs.” Transplant Proc 4, no. 4 (December 1972): 439–46.
    Link to Item
  - Seigler, H. F., J. C. Gunnells, R. R. Robinson, F. E. Ward, D. B. Amos, D. T. Rowlands, P. M. Burkholder, W. J. Klein, and D. L. Stickel. “Renal transplantation between HL-A identical donor-recipient pairs. Functional and morphological evaluation.” J Clin Invest 51, no. 12 (December 1972): 3200–3215. https://doi.org/10.1172/JCI107147.
    Full Text Link to Item
  - Seigler, H. F., W. W. Shingleton, R. S. Metzgar, C. E. Buckley, P. M. Bergoc, D. S. Miller, B. F. Fetter, and M. B. Phaup. “Non-specific and specific immunotherapy in patients with melanoma.” Surgery 72, no. 1 (July 1972): 162–74.
    Link to Item
  - Balner, H., A. D. Barnes, J. D’Amaro, C. C. Darrow, P. Démant, B. W. Gabb, A. Piazza, et al. “Joint report of first histocompatibility workshop on primates.” Transplant Proc 4, no. 1 (March 1972): 141–47.
    Link to Item
  - Metzgar, R. S., H. F. Seigler, F. E. Ward, E. D. Hill, and T. Mohanakumar. “Characterization of chimpanzee leukocyte alloantisera.” Transplant Proc 4, no. 1 (March 1972): 49–54.
    Link to Item
  - Seigler, H. F., R. S. Metzgar, F. E. Ward, and D. M. Reid. “Reactions of human HL-A sera with orangutan and gorilla lymphocytes.” Transplant Proc 4, no. 1 (March 1972): 83–86.
    Link to Item
  - Ward, F. E., H. F. Seigler, and R. S. Metzgar. “Cytotoxicity reactions of chimpanzee antisera with human lymphocyte donors phenotyped or genotyped for HL-A.” Transplant Proc 4, no. 1 (March 1972): 63–69.
    Link to Item
  - Metzgar, R. S., H. F. Seigler, F. E. Ward, and D. T. Rowlands. “Immunological studies on eluates from human renal allografts.” Transplantation 13, no. 2 (February 1972): 131–37. https://doi.org/10.1097/00007890-197202000-00012.
    Full Text Link to Item
  - Anderson, E. E., J. F. Glenn, H. F. Seigler, and D. L. Stickel. “Urologic complications in renal transplantation.” J Urol 107, no. 2 (February 1972): 187–92. https://doi.org/10.1016/s0022-5347(17)60979-0.
    Full Text Link to Item
  - Anderson, E. E., J. F. Glenn, H. F. Seigler, R. D. Ensor, and D. L. Stickel. “Urologic morbidity in renal transplantation.” South Med J 64, no. 12 (December 1971): 1513–15. https://doi.org/10.1097/00007611-197112000-00021.
    Full Text Link to Item
  - Amos, D. B., E. E. Anderson, J. F. Glenn, J. C. Gunnells, S. L. Lancaster, J. M. MacQueen, R. R. Robinson, H. F. Seigler, D. L. Stickel, and F. E. Ward. “Selection of donors for kidney transplantation.” Transplant Proc 3, no. 2 (June 1971): 993–1003.
    Link to Item
  - Seigler, H. F., F. E. Ward, D. B. Amos, M. B. Phaup, and D. L. Stickel. “The immunogenicity of human HL-A haplotypesas measured by skin graft survival times and mixed leukocyte reactions.” J Exp Med 133, no. 3 (March 1, 1971): 411–23. https://doi.org/10.1084/jem.133.3.411.
    Full Text Link to Item
  - Seigler, H. F., F. E. Ward, D. B. Amos, and D. L. Stickel. “Comparisons of mixed leukocyte reactions with skin graft survival in families genotyped for HL-A.” Transplant Proc 3, no. 1 (March 1971): 115–17.
    Link to Item
  - Yunis, E. J., J. M. Plate, F. E. Ward, H. F. Seigler, and D. B. Amos. “Anomalous MLR responsiveness among siblings.” Transplant Proc 3, no. 1 (March 1971): 118–20.
    Link to Item
  - Seigler, H. F., W. B. Kremer, R. S. Metzgar, F. E. Ward, A. T. Haung, and D. B. Amos. “HL-A antigenic loss in malignant transformation.” J Natl Cancer Inst 46, no. 3 (March 1971): 577–84.
    Link to Item
  - Anderson, E. E., J. F. Glenn, H. F. Seigler, and D. L. Stickel. “Urologic complications in renal transplantation.” Trans Am Assoc Genitourin Surg 63 (1971): 56–63.
    Link to Item
  - Metzgar, R. S., and H. F. Seigler. “Tissue antigens of man and chimpanzees; their role in xenografting.” Transplant Proc 2, no. 4 (December 1970): 463–67.
    Link to Item
  - Seigler, H. F., D. B. Amos, F. E. Ward, C. H. Andrus, J. G. Southworth, B. G. Hattler, and D. L. Stickel. “Immunogenetics of consanguineous allografts in man. I. Histocompatibility testing and skin allografts.” Ann Surg 172, no. 2 (August 1970): 151–59. https://doi.org/10.1097/00000658-197008000-00001.
    Full Text Link to Item
  - Stickel, D. L., H. F. Seigler, D. B. Amos, F. E. Ward, J. C. Gunnells, A. R. Price, and E. E. Anderson. “Immunogenetics of consanguineous allografts in man. II. Correlation of renal allografting with HL-A genotyping.” Ann Surg 172, no. 2 (August 1970): 160–79. https://doi.org/10.1097/00000658-197008000-00002.
    Full Text Link to Item
  - Seigler, H. F., D. L. Stickel, F. E. Ward, C. H. Andrus, W. J. Klein, J. C. Gunnells, and D. B. Amos. “Correlations of test skin grafts and renal allograft function in human subjects genotyped for HL-A.” Surgery 68, no. 1 (July 1970): 86–91.
    Link to Item
  - Seigler, H. F., and R. S. Metzgar. “Embryonic development of human transplantation antigens.” Transplantation 9, no. 5 (May 1970): 478–86. https://doi.org/10.1097/00007890-197005000-00007.
    Full Text Link to Item
  - Stickel, D. L., H. F. Seigler, D. B. Amos, F. E. Ward, J. G. Southworth, R. R. Robinson, J. C. Gunnells, E. E. Anderson, and J. F. Glenn. “Kidney transplantation using living donors.” N C Med J 31, no. 4 (April 1970): 119–24.
    Link to Item
  - Seigler, H. F., N. F. Mendes, and R. S. Metzgar. “Accelerated rejection of skin grafts in recipients sensitized with extracted human histocompatibility antigens.” Surgery 67, no. 2 (February 1970): 261–66.
    Link to Item
  - Stickel, D. L., H. F. Seigler, and F. E. Ward. “Methods to prevent rejection of homografts in man: a report on living related kidney donor selection by HL-A genotyping.” Am Surg 36, no. 2 (February 1970): 109–15.
    Link to Item
  - Matter, B., C. F. Zukoski, D. A. Killen, and E. Ginn. “Transplanted carcinoma in an immunosuppressed patient.” Transplantation 9, no. 1 (January 1970): 71–74. https://doi.org/10.1097/00007890-197001000-00021.
    Full Text Link to Item
  - Amos, D. B., H. F. Seigler, J. G. Southworth, and F. E. Ward. “Skin graft rejection between subjects genotyped for HL-A.” Transplant Proc 1, no. 1 (March 1969): 342–46.
    Link to Item
  - Rowlands, D. T., R. B. Vanderbeek, H. F. Seigler, and P. A. Ebert. “Rejection of canine cardiac allografts.” Am J Pathol 53, no. 4 (October 1968): 617–29.
    Link to Item
  - Amos, B., F. E. Ward, C. M. Zmijewski, B. G. Hattler, and H. F. Seigler. “Graft donor selection based upon single locus (haplotype) analysis within families.” Transplantation 6, no. 4 (July 1968): 524–34. https://doi.org/10.1097/00007890-196807000-00003.
    Full Text Link to Item
  - Metzgar, R. S., C. M. Zmijewski, H. F. Seigler, and S. R. Oleinick. “A comparison of the leukocyte agglutination and mixed agglutination techniques for detecting human tissue isoantigens.” Transplantation 6, no. 1 (January 1968): 84–90.
    Link to Item
  - Metzgar, R. S., and H. F. Seigler. “Fractionation studies of human antisera containing leukocyte-agglutinating and cytotoxic isoantibodies.” Transplantation 5, no. 2 (January 1, 1967): 310–16. https://doi.org/10.1097/00007890-196703000-00020.
    Full Text
  - PEACOCK, E. E., H. F. SEIGLER, and P. W. BIGGERS. “USE OF TANNED COLLAGEN SPONGES IN THE TREATMENT OF LIVER INJURIES.” Ann Surg 161, no. 2 (February 1965): 238–47. https://doi.org/10.1097/00000658-196502000-00013.
    Full Text Link to Item
- Conference Papers
  - Farrow, N. E., M. C. Turner, A. K. Salama, H. F. Seigler, D. S. Tyler, and G. Beasley. “Overall Survival Improved for Contemporary Patients with Melanoma.” In Annals of Surgical Oncology, 26:S162–S162. SPRINGER, 2019.
    Link to Item
  - Reese, A. S., C. G. Willett, D. S. Tyler, H. F. Seigler, R. W. Clough, and B. G. Czito. “Potential Benefit of Radiation Therapy in Resectable Anorectal Melanoma.” In International Journal of Radiation Oncology*Biology*Physics, 75:S274–75. Elsevier BV, 2009. https://doi.org/10.1016/j.ijrobp.2009.07.633.
    Full Text
  - Posther, K. E., P. J. Mosca, M. A. Selim, W. E. Stanley, J. L. Johnson, D. S. Tyler, and H. F. Seigler. “Histopathologic characteristics, recurrence patterns, and survival of 129 patients with desmoplastic melanoma.” In Annals of Surgical Oncology, 11:S78–S78. Springer Science and Business Media LLC, 2004. https://doi.org/10.1007/bf02524057.
    Full Text
  - White, R., P. Mosca, W. Stanley, J. Johnson, D. S. Tyler, and H. F. Seigler. “Specific active immunotherapy for primary melanoma: Experience with 5399 Patients.” In Annals of Surgical Oncology, 11:S59–60. Springer Science and Business Media LLC, 2004. https://doi.org/10.1007/bf02523997.
    Full Text
  - Gandy, K. L., N. J. Chao, G. D. Long, V. Sartain, H. F. Seigler, and D. A. Rizzieri. “Donor-specific tolerance after hematopoietic reconstitution with Campath-1H treated mobilized peripheral blood cells in a sublethal preconditioning regimen.” In Blood, 100:410A-410A. AMER SOC HEMATOLOGY, 2002.
    Link to Item
  - Gaca, J. G., D. H. Harpole, T. A. D’Amico, T. Pappas, H. F. Seigler, W. G. Wolfe, and S. Tyler. “Pathologic nodal status predicts disease-free survival after neoadjuvant chemoradiation for gastroesophageal junction carcinoma.” In Gastroenterology, 123:1–2. W B SAUNDERS CO, 2002.
    Link to Item
  - Kalady, M. F., D. C. White, M. W. Onaitis, E. Coleman, H. F. Seigler, and D. Tyler. “Validation of delayed sentinel lymph node mapping for melanoma.” In Cancer Journal, 7:521–22. JONES AND BARTLETT PUBLISHERS, 2001.
    Link to Item
  - Gonzalez-Stawinski, Gonzalo V., Jason M. Rovak, Hillard F. Seigler, John P. Grant, and Theodore N. Pappas. “Poor outcome and quality of life in female patients undergoing secondary surgery for recurrent peptic ulcer disease.” In Gastroenterology, 120:A491–A491. Elsevier BV, 2001. https://doi.org/10.1016/s0016-5085(08)82434-1.
    Full Text
  - Rodan, Bruce A., Dennis K. Heaston, Charles E. Putman, Melvyn Korobkin, Hilliard F. Seigler, James T. T. Chen, Richard S. Breiman, Panol C. Ram, and Carl E. Ravin. “SOLITARY PULMONARY METASTASIS IN ADVANCED LOCAL MALIGNANT MELANOMAS.” In Investigative Radiology, 16:426–426. Ovid Technologies (Wolters Kluwer Health), 1981. https://doi.org/10.1097/00004424-198109000-00132.
    Full Text

Some information on this profile has been compiled automatically from Duke databases and external sources. (Our About page explains how this works.) If you see a problem with the information, please write to Scholars@Duke and let us know. We will reply promptly.

Education, Training, & Certifications

Previous Appointments & Affiliations

Selected Grants

Selected Publications

Books

Academic Articles

Conference Papers