Skip to main content
Journal cover image

Synthesis and characterization of copper(II) complexes of cysteinyldopa and benzothiazine model ligands related to pheomelanin.

Publication ,  Journal Article
Tesema, YT; Pham, DM; Franz, KJ
Published in: Inorganic chemistry
August 2006

A new cysteinyldopa model ligand Cydo {3-[(2-aminoethyl)sulfanyl]-4,6-di-tert-butylbenzene-1,2-diol} was prepared and its reactivity with Cu(II) explored. Under anaerobic conditions, tetranuclear [Cu4(Cydo)4] is isolated, but in the presence of O2, a benzothiazine intermediate accumulates that is trapped as the Cu(II) complex [Cu(zine)2]. Under slightly different reaction conditions, the benzothiazine further oxidizes to benzothiazole (zole). All three compounds were characterized by X-ray crystallography, and the reactions were monitored spectrophotometrically.

Duke Scholars

Published In

Inorganic chemistry

DOI

EISSN

1520-510X

ISSN

0020-1669

Publication Date

August 2006

Volume

45

Issue

16

Start / End Page

6102 / 6104

Related Subject Headings

  • Thiazines
  • Melanins
  • Ligands
  • Inorganic & Nuclear Chemistry
  • Cysteinyldopa
  • Copper
  • Benzene Derivatives
  • 3403 Macromolecular and materials chemistry
  • 3402 Inorganic chemistry
  • 0399 Other Chemical Sciences
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Tesema, Y. T., Pham, D. M., & Franz, K. J. (2006). Synthesis and characterization of copper(II) complexes of cysteinyldopa and benzothiazine model ligands related to pheomelanin. Inorganic Chemistry, 45(16), 6102–6104. https://doi.org/10.1021/ic060262n
Tesema, Yohannes T., David M. Pham, and Katherine J. Franz. “Synthesis and characterization of copper(II) complexes of cysteinyldopa and benzothiazine model ligands related to pheomelanin.Inorganic Chemistry 45, no. 16 (August 2006): 6102–4. https://doi.org/10.1021/ic060262n.
Tesema, Yohannes T., et al. “Synthesis and characterization of copper(II) complexes of cysteinyldopa and benzothiazine model ligands related to pheomelanin.Inorganic Chemistry, vol. 45, no. 16, Aug. 2006, pp. 6102–04. Epmc, doi:10.1021/ic060262n.
Journal cover image

Published In

Inorganic chemistry

DOI

EISSN

1520-510X

ISSN

0020-1669

Publication Date

August 2006

Volume

45

Issue

16

Start / End Page

6102 / 6104

Related Subject Headings

  • Thiazines
  • Melanins
  • Ligands
  • Inorganic & Nuclear Chemistry
  • Cysteinyldopa
  • Copper
  • Benzene Derivatives
  • 3403 Macromolecular and materials chemistry
  • 3402 Inorganic chemistry
  • 0399 Other Chemical Sciences