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Decreased thrombogenicity of vascular prostheses following gas denucleation by hydrostatic pressure.

Publication ,  Journal Article
Demas, CP; Vann, R; Ritter, E; Sepka, RS; Klitzman, B; Barwick, WJ
Published in: Plast Reconstr Surg
December 1988

The high rate of thrombosis of 1.0-mm polytetrafluoroethylene (PTFE) grafts has limited their use in microvascular surgery. One possible reason for this is the blood-gas interface due to entrapped air in the interstices. The present study examines the effect on patency rates of elimination of this blood-gas interface by high pressurization. Comparing pressurized and nonpressurized grafts in the same animals showed a patency rate of 100 percent at 7 days for treated grafts, while the control (nonpressurized) grafts had all clotted by 1 hour. The implications for microvascular surgery as well as vascular surgery in general are discussed.

Duke Scholars

Published In

Plast Reconstr Surg

DOI

ISSN

0032-1052

Publication Date

December 1988

Volume

82

Issue

6

Start / End Page

1042 / 1045

Location

United States

Related Subject Headings

  • Vascular Patency
  • Surgery
  • Rats
  • Polytetrafluoroethylene
  • Male
  • Hydrostatic Pressure
  • Graft Occlusion, Vascular
  • Embolism, Air
  • Blood Vessel Prosthesis
  • Animals
 

Citation

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Demas, C. P., Vann, R., Ritter, E., Sepka, R. S., Klitzman, B., & Barwick, W. J. (1988). Decreased thrombogenicity of vascular prostheses following gas denucleation by hydrostatic pressure. Plast Reconstr Surg, 82(6), 1042–1045. https://doi.org/10.1097/00006534-198812000-00016
Demas, C. P., R. Vann, E. Ritter, R. S. Sepka, B. Klitzman, and W. J. Barwick. “Decreased thrombogenicity of vascular prostheses following gas denucleation by hydrostatic pressure.Plast Reconstr Surg 82, no. 6 (December 1988): 1042–45. https://doi.org/10.1097/00006534-198812000-00016.
Demas CP, Vann R, Ritter E, Sepka RS, Klitzman B, Barwick WJ. Decreased thrombogenicity of vascular prostheses following gas denucleation by hydrostatic pressure. Plast Reconstr Surg. 1988 Dec;82(6):1042–5.
Demas, C. P., et al. “Decreased thrombogenicity of vascular prostheses following gas denucleation by hydrostatic pressure.Plast Reconstr Surg, vol. 82, no. 6, Dec. 1988, pp. 1042–45. Pubmed, doi:10.1097/00006534-198812000-00016.
Demas CP, Vann R, Ritter E, Sepka RS, Klitzman B, Barwick WJ. Decreased thrombogenicity of vascular prostheses following gas denucleation by hydrostatic pressure. Plast Reconstr Surg. 1988 Dec;82(6):1042–1045.

Published In

Plast Reconstr Surg

DOI

ISSN

0032-1052

Publication Date

December 1988

Volume

82

Issue

6

Start / End Page

1042 / 1045

Location

United States

Related Subject Headings

  • Vascular Patency
  • Surgery
  • Rats
  • Polytetrafluoroethylene
  • Male
  • Hydrostatic Pressure
  • Graft Occlusion, Vascular
  • Embolism, Air
  • Blood Vessel Prosthesis
  • Animals