Bruce Klitzman | Scholars@Duke

Bruce Klitzman
Associate Professor in Surgery

Our overriding interests are in the fields of tissue engineering, wound healing, biosensors, and long term improvement of medical device implantation. My basic research interests are in the area of physiological mechanisms of optimizing substrate transport to tissue. This broad topic covers studies on a whole animal, whole organ, hemorheological, microvascular, cellular, ultrastructural, and molecular level. The current projects include:
1) control of blood flow and flow distribution in the microcirculation,
2) the effects of long-term synthetic and biologic implants on substrate transport to tissues,
3) tissue engineering; combining isolated cells, especially adult stem cells, with biomaterials to form specialized composite structures for implantation, with particular emphasis on endothelial cell physiology and its alteration by isolation and seeding on biomaterials.
4) decreasing the thrombogenicity of synthetic blood vessels and other blood-contacting devices, and improving their overall performance and biocompatibility.
5) reducing tissue damage resulting from abnormal perfusion (e.g., relative ischemia, anoxia, etc.) and therapies which minimize ischemic damage.
6) biosensor function, particularly glucose sensors in normal and diabetics.
7) measurement of tissue blood flow and oxygenation as an indicator of tissue viability and functional potential.
8) development of biocompatible materials for soft tissue reconstruction or augmentation.
9) improving performance of glaucoma drainage devices by directing a more favorable foreign body reaction
10) wound healing; particularly internal healing around foreign materials and the effect and prevention of microbes around implanted devices.

Current Appointments & Affiliations

Associate Professor in Surgery, Surgery, Plastic, Maxillofacial, and Oral Surgery, Surgery 2021
Assistant Research Professor in Cell Biology, Cell Biology, Basic Science Departments 1994
Associate Research Professor of Biomedical Engineering, Biomedical Engineering, Pratt School of Engineering 2010
Core Faculty in Innovation & Entrepreneurship, Duke Innovation & Entrepreneurship, Initiatives 2018

Contact Information

0112 Baker House, Trent Dr, Durham, NC 27710
Plastic Surgery, Duke University Medical Center, Durham, NC 27710
klitz@duke.edu (919) 630-7445
Google Scholar

Background
Education, Training, & Certifications
- Ph.D., University of Virginia 1979
Previous Appointments & Affiliations
- Associate Professor of Surgery, Surgery, Plastic, Maxillofacial, and Oral Surgery, Surgery 2008 - 2020
- Member of the Duke Cancer Institute, Duke Cancer Institute, Institutes and Centers 1985 - 2015
- Associate Research Professor of Biomedical Engineering, Biomedical Engineering, Pratt School of Engineering 2008 - 2010
- Associate Research Professor of Biomedical Engineering, Biomedical Engineering, Pratt School of Engineering 2008 - 2009
- Associate Research Professor of Biomedical Engineering, Biomedical Engineering, Pratt School of Engineering 2007 - 2008
- Assistant Research Professor of Biomedical Engineering, Biomedical Engineering, Pratt School of Engineering 2003 - 2007
- Associate Research Professor in Surgery, Surgery, Plastic, Maxillofacial, and Oral Surgery, Surgery 2005 - 2006
- Assistant Research Professor in Surgery, Surgery, Plastic, Maxillofacial, and Oral Surgery, Surgery 1994 - 2005
- Assistant Medical Research Professor of Physiology, Immunology, Basic Science Departments 1987 - 1988
Leadership & Clinical Positions at Duke
- Director, Tissue Viability Service, 1988-2003
  Study Program Director, Biomedical Engineering and Surgery Study Program, Third Year Medical Students, 2008-
Academic Positions Outside Duke
- Adjunct Associate Professor, Biomedical Engineering, Louisiana Tech University, Ruston, LA. 1982 - 1985
Recognition
In the News
- SEP 1, 2007 Time Magazine
  
  Time's Best Inventions of the Year
Awards & Honors
Research
Selected Grants
- University Training Program in Biomolecular and Tissue Engineering awarded by National Institutes of Health 1994 - 2027
- A Novel Scaffold to Promote Skin Regeneration awarded by FirstString Research, Inc. 2017 - 2019
- Bruce Klitzman Sponsored Professorship awarded by Profusa, Inc. 2017 - 2018
- Linking oxygen and bacterial ecology in necrotizing enterocolitis awarded by Hartwell Foundation 2015 - 2018
- In Vivo Testing of Glaucoma Drainage Devices in Rabbits awarded by Camras Vision, Inc. 2015 - 2016
- Establishing Implantable Oxygen Sensors and Correlation with Flap Viability awarded by The Plastic Surgery Foundation 2014 - 2016
- Plasmonics-Active SERS Nanoplatforms for In Vivo Diagnostics awarded by Defense Advanced Research Projects Agency 2012 - 2016
- Nanoplatform for Tracking Adipose-Derived Stem Cell Migration awarded by Southeastern Society of Plastic and Reconstructive Surgeons 2015 - 2016
- Luminescent Sensors for continuous monitoring of PAD awarded by Profusa, Inc. 2015 - 2016
- Biosensor Biocompatibility awarded by National Institutes of Health 1999 - 2015
- Optical measurement of subcutaneous glucose in rats awarded by Profusa, Inc. 2012 - 2014
- Non Muscle Myosin II Contractility Putatively Regulates Scar Contracture awarded by National Institutes of Health 2008 - 2013
- EPC Adhesion to Teflon-AF and ePTFE Vascular Grafts awarded by National Institutes of Health 1990 - 2013
- Biocompatibility of Implantable Biosensors awarded by Profusa, Inc. 2011 - 2012
- Advanced BioMaterials as Implantable Chemical Sensors awarded by Profusa, Inc. 2011
- Training in Biomolecular and Tissue Engineering awarded by National Institutes of Health 2003 - 2009
- Cell Viability in Implantable Diffusion Chambers awarded by National Institutes of Health 2000 - 2005
- Cellular Engineering of Chronically Implanted Devices awarded by NC Biotechnology Center 1999 - 2000
- Heat & Radiation Effects On Tumor Microcirculation awarded by National Institutes of Health 1997 - 1999
- Effects Of Heat And Radiation On Tumor awarded by National Institutes of Health 1996 - 1999
- Event Sponsorship: Tissue Engineering Interest Group awarded by NC Biotechnology Center 1998
- Effects Of Heat And Radiation On Tumor Microcirculation awarded by National Institutes of Health 1985 - 1996
- Effects Of Systemic Hematocrit On Microvessel Hematocrit awarded by National Institutes of Health 1986 - 1987
External Relationships
- Alievio (formerly Camras Vision)
- Chatham Bay Group/Everence
Publications & Artistic Works
Selected Publications
- Academic Articles
  - Straube, Tobias L., Stewart Farling, Marc A. Deshusses, Bruce Klitzman, Ira M. Cheifetz, and Travis P. Vesel. “Intravascular Gas Exchange: Physiology, Literature Review, and Current Efforts.” Respir Care 67, no. 4 (April 2022): 480–93. https://doi.org/10.4187/respcare.09288.
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  - Wu, Zi Jun, Mohamed M. Ibrahim, Amanda R. Sergesketter, Ryan M. Schweller, Brett T. Phillips, and Bruce Klitzman. “The Influence of Topical Vasodilator-Induced Pharmacologic Delay on Cutaneous Flap Viability and Vascular Remodeling.” Plast Reconstr Surg 149, no. 3 (March 1, 2022): 629–37. https://doi.org/10.1097/PRS.0000000000008829.
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  - Ruppert, David S., Mahmoud M. Mohammed, Mohamed M. Ibrahim, Emilio O. Bachtiar, Kevin Erning, Kayvan Ansari, Jeffrey I. Everitt, et al. “Poly(lactide-co-ε-caprolactone) scaffold promotes equivalent tissue integration and supports skin grafts compared to a predicate collagen scaffold.” Wound Repair Regen 29, no. 6 (November 2021): 1035–50. https://doi.org/10.1111/wrr.12951.
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  - Farling, Stewart, Tobias L. Straube, Travis P. Vesel, Nick Bottenus, Bruce Klitzman, Ira M. Cheifetz, and Marc A. Deshusses. “Development of a novel intravascular oxygenator catheter: Oxygen mass transfer properties across nonporous hollow fiber membranes.” Biotechnol Bioeng 118, no. 1 (January 2021): 345–56. https://doi.org/10.1002/bit.27574.
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  - Ibrahim, Mohamed M., Preet S. Patel, Zi Jun Wu, Jennifer S. Chien, Natalie A. Wisniewski, Mahmoud M. Mohammed, and Bruce Klitzman. “Detection of flap tissue ischemia in a rat model: Real-time monitoring of changes in oxygenation and perfusion through injectable biosensors.” Surgery 168, no. 5 (November 2020): 926–34. https://doi.org/10.1016/j.surg.2020.04.040.
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  - Kanick, Stephen C., Peter A. Schneider, Bruce Klitzman, Natalie A. Wisniewski, and Kerstin Rebrin. “Continuous monitoring of interstitial tissue oxygen using subcutaneous oxygen microsensors: In vivo characterization in healthy volunteers.” Microvasc Res 124 (July 2019): 6–18. https://doi.org/10.1016/j.mvr.2019.02.002.
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  - Scheuermann, Uwe, Mohamed M. Ibrahim, John Yerxa, William Parker, Matthew G. Hartwig, Bruce Klitzman, and Andrew S. Barbas. “Machine Perfusion of Liver Grafts With Implantable Oxygen Biosensors: Proof of Concept Study in a Rodent Model.” Transplant Direct 5, no. 7 (July 2019): e463. https://doi.org/10.1097/TXD.0000000000000905.
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  - Wang, H. N., J. K. Register, A. M. Fales, N. Gandra, E. H. Cho, A. Boico, G. M. Palmer, B. Klitzman, and T. Vo-Dinh. “Surface-enhanced Raman scattering nanosensors for in vivo detection of nucleic acid targets in a large animal model.” Nano Research 11, no. 8 (August 1, 2018): 4005–16. https://doi.org/10.1007/s12274-018-1982-3.
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  - Blueschke, Gert, Alina Boico, Ayele H. Negussie, Pavel Yarmolenko, Bradford J. Wood, Ivan Spasojevic, Ping Fan, et al. “Enhanced Drug Delivery to the Skin Using Liposomes.” Plast Reconstr Surg Glob Open 6, no. 7 (July 2018): e1739. https://doi.org/10.1097/GOX.0000000000001739.
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  - Reese, Aspen T., Eugenia H. Cho, Bruce Klitzman, Scott P. Nichols, Natalie A. Wisniewski, Max M. Villa, Heather K. Durand, et al. “Antibiotic-induced changes in the microbiota disrupt redox dynamics in the gut.” Elife 7 (June 19, 2018). https://doi.org/10.7554/eLife.35987.
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  - Ibrahim, Mohamed, Jennifer Bond, Manuel A. Medina, Lei Chen, Carlos Quiles, George Kokosis, Latif Bashirov, Bruce Klitzman, and Howard Levinson. “Characterization of the Foreign Body Response to Common Surgical Biomaterials in a Murine Model.” Eur J Plast Surg 40, no. 5 (November 2017): 383–92. https://doi.org/10.1007/s00238-017-1308-9.
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  - Chien, Jennifer S., Mahmoud Mohammed, Hysem Eldik, Mohamed M. Ibrahim, Jeremy Martinez, Scott P. Nichols, Natalie Wisniewski, and Bruce Klitzman. “Injectable Phosphorescence-based Oxygen Biosensors Identify Post Ischemic Reactive Hyperoxia.” Sci Rep 7, no. 1 (August 15, 2017): 8255. https://doi.org/10.1038/s41598-017-08490-0.
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  - Klitzman, B., J. S. Chien, M. Mohammed, H. Eldik, M. ibrahim, J. Martinez, S. P. Nichols, and N. A. Wisniewski. “Injectable Phosphorescence-based Oxygen Biosensors Identify Post Ischemic Reactive Hyperoxia.” Nature Scientific Reports 7, no. 1 (August 15, 2017): 1–10. https://doi.org/10.1038/s41598-017-08490-0.
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  - Schweller, Ryan M., Zi Jun Wu, Bruce Klitzman, and Jennifer L. West. “Stiffness of Protease Sensitive and Cell Adhesive PEG Hydrogels Promotes Neovascularization In Vivo.” Ann Biomed Eng 45, no. 6 (June 2017): 1387–98. https://doi.org/10.1007/s10439-017-1822-8.
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  - Wisniewski, Natalie A., Scott P. Nichols, Soya J. Gamsey, Steve Pullins, Kit Y. Au-Yeung, Bruce Klitzman, and Kristen L. Helton. “Tissue-Integrating Oxygen Sensors: Continuous Tracking of Tissue Hypoxia.” Adv Exp Med Biol 977 (2017): 377–83. https://doi.org/10.1007/978-3-319-55231-6_49.
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  - Ibrahim, M. M., M. A. Medina, J. Bond, L. Chen, C. Quiles, G. Kokosis, L. Bashirov, A. Selim, B. Klitzman, and H. Levinson. “FOREIGN BODY REACTION TO COMMONLY USED SURGICAL BIOMATERIALS.” Wound Repair and Regeneration 24, no. 2 (March 1, 2016): A12–13.
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  - Ibrahim, M. M., Z. Wu, J. Chien, and B. Klitzman. “NOVEL IMPLANTABLE OPTICAL OXYGEN MONITOR TO DETECT FLAP VIABILITY.” Wound Repair and Regeneration 24, no. 2 (March 1, 2016): A13–A13.
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  - Ibrahim, M. M., Z. Wu, R. Schweller, B. Phillips, and B. Klitzman. “TOPICAL VASODILATOR INDUCES PHARMACOLOGICAL DELAY ON CUTANEOUS FLAP VIABILITY AND VASCULAR REMODELING.” Wound Repair and Regeneration 24, no. 2 (March 1, 2016): A13–A13.
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  - Lorden, E., T. Ramchal, P. Chandra, L. Bashirov, M. M. Ibrahim, E. Hammett, B. Klitzman, et al. “PORE SIZE IMPACTS HYPERTROPHIC SCARRING-RELATED OUTCOMES IN 3D PRINTED POLYURETHANE SCAFFOLDS.” Wound Repair and Regeneration 24, no. 2 (March 1, 2016): A16–17.
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  - Laux, Peter, Tewes Tralau, Jutta Tentschert, Annegret Blume, Sascha Al Dahouk, Wolfgang Bäumler, Eric Bernstein, et al. “A medical-toxicological view of tattooing.” Lancet 387, no. 10016 (January 23, 2016): 395–402. https://doi.org/10.1016/S0140-6736(15)60215-X.
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  - Vallejo-Heligon, Suzana G., Nga L. Brown, William M. Reichert, and Bruce Klitzman. “Porous, Dexamethasone-loaded polyurethane coatings extend performance window of implantable glucose sensors in vivo.” Acta Biomater 30 (January 2016): 106–15. https://doi.org/10.1016/j.actbio.2015.10.045.
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  - Register, Janna K., Andrew M. Fales, Hsin-Neng Wang, Stephen J. Norton, Eugenia H. Cho, Alina Boico, Sulolit Pradhan, et al. “In vivo detection of SERS-encoded plasmonic nanostars in human skin grafts and live animal models.” Anal Bioanal Chem 407, no. 27 (November 2015): 8215–24. https://doi.org/10.1007/s00216-015-8939-0.
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  - Jung, Youngmee, HaYeun Ji, Zaozao Chen, Hon Fai Chan, Leigh Atchison, Bruce Klitzman, George Truskey, and Kam W. Leong. “Scaffold-free, Human Mesenchymal Stem Cell-Based Tissue Engineered Blood Vessels.” Sci Rep 5 (October 12, 2015): 15116. https://doi.org/10.1038/srep15116.
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  - Ibrahim, Mohamed Magdy, Jennifer Bond, Andrew Bergeron, Kyle J. Miller, Tosan Ehanire, Carlos Quiles, Elizabeth R. Lorden, et al. “A novel immune competent murine hypertrophic scar contracture model: a tool to elucidate disease mechanism and develop new therapies.” Wound Repair Regen 22, no. 6 (November 2014): 755–64. https://doi.org/10.1111/wrr.12238.
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  - Brown, Nga L., Michael B. Rose, Gert Blueschke, Eugenia H. Cho, Mark H. Schoenfisch, Detlev Erdmann, and Bruce Klitzman. “Bioburden after Staphylococcus aureus inoculation in type 1 diabetic rats undergoing internal fixation.” Plast Reconstr Surg 134, no. 3 (September 2014): 412e-419e. https://doi.org/10.1097/PRS.0000000000000434.
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  - Radiloff, Daniel, Yulin Zhao, Alina Boico, Gert Blueschke, Gregory Palmer, Andrew Fontanella, Mark Dewhirst, et al. “Anti-hypotensive treatment and endothelin blockade synergistically antagonize exercise fatigue in rats under simulated high altitude.” Plos One 9, no. 6 (2014): e99309. https://doi.org/10.1371/journal.pone.0099309.
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  - Hollenbeck, Scott T., Annika Senghaas, Issei Komatsu, Ying Zhang, Detlev Erdmann, and Bruce Klitzman. “Tissue engraftment of hypoxic-preconditioned adipose-derived stem cells improves flap viability.” Wound Repair Regen 20, no. 6 (November 2012): 872–78. https://doi.org/10.1111/j.1524-475X.2012.00854.x.
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  - Nichols, Scott P., Ahyeon Koh, Nga L. Brown, Michael B. Rose, Bin Sun, Danielle L. Slomberg, Daniel A. Riccio, Bruce Klitzman, and Mark H. Schoenfisch. “The effect of nitric oxide surface flux on the foreign body response to subcutaneous implants.” Biomaterials 33, no. 27 (September 2012): 6305–12. https://doi.org/10.1016/j.biomaterials.2012.05.053.
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  - Stroncek, J. D., L. C. Ren, B. Klitzman, and W. M. Reichert. “Patient-derived endothelial progenitor cells improve vascular graft patency in a rodent model.” Acta Biomater 8, no. 1 (January 2012): 201–8. https://doi.org/10.1016/j.actbio.2011.09.002.
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  - Le, Nga N., Michael B. Rose, Howard Levinson, and Bruce Klitzman. “Implant healing in experimental animal models of diabetes.” J Diabetes Sci Technol 5, no. 3 (May 1, 2011): 605–18. https://doi.org/10.1177/193229681100500315.
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  - Nichols, Scott P., Nga N. Le, Bruce Klitzman, and Mark H. Schoenfisch. “Increased in vivo glucose recovery via nitric oxide release.” Anal Chem 83, no. 4 (February 15, 2011): 1180–84. https://doi.org/10.1021/ac103070t.
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  - DeCroos, Francis Char, Yuji Kondo, Daniel Mordes, Maria Regina Lee, Sameer Ahmad, Sanjay Asrani, R Rand Allingham, Kevin C. Olbrich, and Bruce Klitzman. “In vitro fluid dynamics of the Ahmed glaucoma valve modified with expanded polytetrafluoroethylene.” Curr Eye Res 36, no. 2 (February 2011): 112–17. https://doi.org/10.3109/02713683.2010.512115.
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  - Prichard, Heather L., Thies Schroeder, William M. Reichert, and Bruce Klitzman. “Bioluminescence imaging of glucose in tissue surrounding polyurethane and glucose sensor implants.” J Diabetes Sci Technol 4, no. 5 (September 1, 2010): 1055–62. https://doi.org/10.1177/193229681000400504.
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  - Yang, Jun, Detlev Erdmann, J. C. Chang, Issei Komatsu, YiXin Zhang, DanRu Wang, Michael S. Hodavance, et al. “A model of sequential heart and composite tissue allotransplant in rats.” Plast Reconstr Surg 126, no. 1 (July 2010): 80–86. https://doi.org/10.1097/PRS.0b013e3181dbbb64.
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  - Koschwanez, H. E., W. M. Reichert, and B. Klitzman. “Intravital microscopy evaluation of angiogenesis and its effects on glucose sensor performance.” J Biomed Mater Res A 93, no. 4 (June 15, 2010): 1348–57. https://doi.org/10.1002/jbm.a.32630.
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  - Huang, Xin, Stefan Zauscher, Bruce Klitzman, George A. Truskey, William M. Reichert, Daniel J. Kenan, and Mark W. Grinstaff. “Peptide interfacial biomaterials improve endothelial cell adhesion and spreading on synthetic polyglycolic acid materials.” Ann Biomed Eng 38, no. 6 (June 2010): 1965–76. https://doi.org/10.1007/s10439-010-9986-5.
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  - Talaat, W. M., T. A. McGraw, and B. Klitzman. “Relationship between the canthal-tragus distance and the puncture point in temporomandibular joint arthroscopy.” Int J Oral Maxillofac Surg 39, no. 1 (January 2010): 57–60. https://doi.org/10.1016/j.ijom.2009.11.016.
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  - DeCroos, Francis Char, Sameer Ahmad, Yuji Kondo, Jessica Chow, Daniel Mordes, Maria Regina Lee, Sanjay Asrani, R Rand Allingham, Kevin C. Olbrich, and Bruce Klitzman. “Expanded polytetrafluoroethylene membrane alters tissue response to implanted Ahmed glaucoma valve.” Curr Eye Res 34, no. 7 (July 2009): 562–67. https://doi.org/10.1080/02713680902963167.
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  - Pradka, S. P., Y. S. Ong, Y. Zhang, S. J. Davis, A. Baccarani, C. Messmer, T. A. Fields, D. Erdmann, B. Klitzman, and L. S. Levin. “Increased signs of acute rejection with ischemic time in a rat musculocutaneous allotransplant model.” Transplant Proc 41, no. 2 (March 2009): 531–36. https://doi.org/10.1016/j.transproceed.2009.01.021.
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  - Schutte, Robert J., Lola Xie, Bruce Klitzman, and William M. Reichert. “In vivo cytokine-associated responses to biomaterials.” Biomaterials 30, no. 2 (January 2009): 160–68. https://doi.org/10.1016/j.biomaterials.2008.09.026.
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  - Koschwanez, H. E., F. Y. Yap, B. Klitzman, and W. M. Reichert. “In vitro and in vivo characterization of porous poly-L-lactic acid coatings for subcutaneously implanted glucose sensors.” J Biomed Mater Res A 87, no. 3 (December 1, 2008): 792–807. https://doi.org/10.1002/jbm.a.31824.
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  - Koschwanez, Heidi E., Bruce Klitzman, and W Monty Reichert. “Percutaneous window chamber method for chronic intravital microscopy of sensor-tissue interactions.” J Diabetes Sci Technol 2, no. 6 (November 2008): 977–83. https://doi.org/10.1177/193229680800200608.
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  - Prichard, Heather L., William Reichert, and Bruce Klitzman. “IFATS collection: Adipose-derived stromal cells improve the foreign body response.” Stem Cells 26, no. 10 (October 2008): 2691–95. https://doi.org/10.1634/stemcells.2008-0140.
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  - Mischen, Blaine T., Keith E. Follmar, Kurtis E. Moyer, Ben Buehrer, Kevin C. Olbrich, L Scott Levin, Bruce Klitzman, and Detlev Erdmann. “Metabolic and functional characterization of human adipose-derived stem cells in tissue engineering.” Plast Reconstr Surg 122, no. 3 (September 2008): 725–38. https://doi.org/10.1097/PRS.0b013e318180ec9f.
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  - Kovach, Stephen J., Kim E. Koger, Bruce Klitzman, Gunter Germann, and L Scott Levin. “Advantages of minimally invasive, balloon-dissector-assisted tissue expander placement: a clinical and experimental study.” Ann Plast Surg 60, no. 1 (January 2008): 89–97. https://doi.org/10.1097/SAP.0b013e318052ac32.
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  - Hetrick, Evan M., Heather L. Prichard, Bruce Klitzman, and Mark H. Schoenfisch. “Reduced foreign body response at nitric oxide-releasing subcutaneous implants.” Biomaterials 28, no. 31 (November 2007): 4571–80. https://doi.org/10.1016/j.biomaterials.2007.06.036.
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  - Baccarani, Alessio, Koji Yasui, Kevin C. Olbrich, Ahmed El-Sabbagh, Stephen Kovach, Keith E. Follmar, Detlev Erdmann, et al. “Efficacy of ethyl nitrite in reversing surgical vasospasm.” J Reconstr Microsurg 23, no. 5 (July 2007): 257–62. https://doi.org/10.1055/s-2007-985206.
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  - Norton, L. W., H. E. Koschwanez, N. A. Wisniewski, B. Klitzman, and W. M. Reichert. “Vascular endothelial growth factor and dexamethasone release from nonfouling sensor coatings affect the foreign body response.” J Biomed Mater Res A 81, no. 4 (June 15, 2007): 858–69. https://doi.org/10.1002/jbm.a.31088.
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  - Follmar, Keith E., Heather L. Prichard, Francis C. DeCroos, Howard T. Wang, L Scott Levin, Bruce Klitzman, Kevin C. Olbrich, and Detlev Erdmann. “Combined bone allograft and adipose-derived stem cell autograft in a rabbit model.” Ann Plast Surg 58, no. 5 (May 2007): 561–65. https://doi.org/10.1097/01.sap.0000245119.74126.09.
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  - Prichard, Heather L., William M. Reichert, and Bruce Klitzman. “Adult adipose-derived stem cell attachment to biomaterials.” Biomaterials 28, no. 6 (February 2007): 936–46. https://doi.org/10.1016/j.biomaterials.2006.09.012.
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  - Heitmann, Christoph, Farah N. Khan, Detlev Erdmann, Kevin C. Olbrich, A. Adam Sharkawy, and Bruce Klitzman. “Vein graft anastomoses with magnets.” J Plast Reconstr Aesthet Surg 60, no. 12 (2007): 1296–1301. https://doi.org/10.1016/j.bjps.2006.10.017.
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  - Lanzen, Jennifer, Rod D. Braun, Bruce Klitzman, David Brizel, Timothy W. Secomb, and Mark W. Dewhirst. “Direct demonstration of instabilities in oxygen concentrations within the extravascular compartment of an experimental tumor.” Cancer Res 66, no. 4 (February 15, 2006): 2219–23. https://doi.org/10.1158/0008-5472.CAN-03-2958.
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  - Ko, Jason, Joel Ross, Hani Awad, Herbert Hurwitz, and Bruce Klitzman. “The effects of ZD6474, an inhibitor of VEGF signaling, on cutaneous wound healing in mice.” J Surg Res 129, no. 2 (December 2005): 251–59. https://doi.org/10.1016/j.jss.2005.05.006.
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  - Nablo, Brian J., Heather L. Prichard, Renita D. Butler, Bruce Klitzman, and Mark H. Schoenfisch. “Inhibition of implant-associated infections via nitric oxide release.” Biomaterials 26, no. 34 (December 2005): 6984–90. https://doi.org/10.1016/j.biomaterials.2005.05.017.
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  - Sorg, Brian S., Cathryn D. Peltz, Bruce Klitzman, and Mark W. Dewhirst. “Method for improved accuracy in endogenous urea recovery marker calibrations for microdialysis in tumors.” J Pharmacol Toxicol Methods 52, no. 3 (November 2005): 341–49. https://doi.org/10.1016/j.vascn.2005.05.004.
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  - Olbrich, Kevin C., Ricardo Meade, William Bruno, Lior Heller, Bruce Klitzman, and L Scott Levin. “Halofuginone inhibits collagen deposition in fibrous capsules around implants.” Ann Plast Surg 54, no. 3 (March 2005): 293–96.
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  - Chan, Bernard P., Wenge Liu, Bruce Klitzman, William M. Reichert, and George A. Truskey. “In vivo performance of dual ligand augmented endothelialized expanded polytetrafluoroethylene vascular grafts.” J Biomed Mater Res B Appl Biomater 72, no. 1 (January 15, 2005): 52–63. https://doi.org/10.1002/jbm.b.30114.
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  - Dai, Qunsheng, Jianhua Huang, Bruce Klitzman, Chunming Dong, Pascal J. Goldschmidt-Clermont, Keith L. March, Joseph Rokovich, et al. “Engineered zinc finger-activating vascular endothelial growth factor transcription factor plasmid DNA induces therapeutic angiogenesis in rabbits with hindlimb ischemia.” Circulation 110, no. 16 (October 19, 2004): 2467–75. https://doi.org/10.1161/01.CIR.0000145139.53840.49.
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  - Erdmann, Detlev, Anne M. Pippen, Kenneth J. Moquin, Ranya Sweis, Laura E. Niklason, L Scott Levin, Kevin C. Olbrich, and Bruce Klitzman. “Immunohistochemical identification of vascular endothelial growth factor in pig latissimus dorsi musculocutaneous flaps following ischemia-reperfusion injury.” Ann Plast Surg 53, no. 4 (October 2004): 398–403. https://doi.org/10.1097/01.sap.0000125503.69220.69.
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  - Erdmann, Detlev, Ranya Sweis, Christoph Heitmann, Koji Yasui, Kevin C. Olbrich, L Scott Levin, A Adam Sharkawy, and Bruce Klitzman. “Side-to-side sutureless vascular anastomosis with magnets.” J Vasc Surg 40, no. 3 (September 2004): 505–11. https://doi.org/10.1016/j.jvs.2004.05.026.
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  - Wong, Michael S., Detlev Erdmann, Ranya Sweis, Christiane Pöllmann, Margaret Farrar, Gregory S. Georgiade, L Scott Levin, Kevin C. Olbrich, and Bruce Klitzman. “Basic fibroblast growth factor expression following surgical delay of rat transverse rectus abdominis myocutaneous flaps.” Plast Reconstr Surg 113, no. 7 (June 2004): 2030–36. https://doi.org/10.1097/01.prs.0000122217.16985.52.
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  - Lockhart, A Craig, Rod D. Braun, Daohai Yu, Joel R. Ross, Mark W. Dewhirst, Bruce Klitzman, Fan Yuan, et al. “A clinical model of dermal wound angiogenesis.” Wound Repair Regen 11, no. 4 (July 2003): 306–13. https://doi.org/10.1046/j.1524-475x.2003.11411.x.
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  - Erdmann, Detlev, Ranya Sweis, Michael S. Wong, Laura E. Niklason, Tracey V. du Laney, L Scott Levin, Bruce Klitzman, and Kevin C. Olbrich. “Vascular endothelial growth factor expression in pig latissimus dorsi myocutaneous flaps after ischemia reperfusion injury.” Plast Reconstr Surg 111, no. 2 (February 2003): 775–80. https://doi.org/10.1097/01.PRS.0000041534.99907.75.
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  - Lockhart, A Craig, Rod D. Braun, Daohai Yu, Joel R. Ross, Mark W. Dewhirst, Jeffrey S. Humphrey, Seth Thompson, et al. “Reduction of wound angiogenesis in patients treated with BMS-275291, a broad spectrum matrix metalloproteinase inhibitor.” Clin Cancer Res 9, no. 2 (February 2003): 586–93.
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  - Stenken, Julie A., William M. Reichert, and Bruce Klitzman. “Magnetic resonance imaging of a tissue/implanted device biointerface using in vivo microdialysis sampling.” Anal Chem 74, no. 18 (September 15, 2002): 4849–54. https://doi.org/10.1021/ac020234w.
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  - Wisniewski, N., B. Klitzman, B. Miller, and W. M. Reichert. “Decreased analyte transport through implanted membranes: differentiation of biofouling from tissue effects.” J Biomed Mater Res 57, no. 4 (December 15, 2001): 513–21. https://doi.org/10.1002/1097-4636(20011215)57:4<513::aid-jbm1197>3.0.co;2-e.
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  - Ettinger, S. N., C. C. Poellmann, N. A. Wisniewski, A. A. Gaskin, J. S. Shoemaker, J. M. Poulson, M. W. Dewhirst, and B. Klitzman. “Urea as a recovery marker for quantitative assessment of tumor interstitial solutes with microdialysis.” Cancer Res 61, no. 21 (November 1, 2001): 7964–70.
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  - Heller, L., L. S. Levin, and B. Klitzman. “Laser Doppler flowmeter monitoring of free-tissue transfers: blood flow in normal and complicated cases.” Plast Reconstr Surg 107, no. 7 (June 2001): 1739–45. https://doi.org/10.1097/00006534-200106000-00015.
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  - Ravin, A. G., K. C. Olbrich, L. S. Levin, A. L. Usala, and B. Klitzman. “Long- and short-term effects of biological hydrogels on capsule microvascular density around implants in rats.” J Biomed Mater Res 58, no. 3 (May 1, 2001): 313–18. https://doi.org/10.1002/1097-4636(2001)58:3<313::aid-jbm1023>3.0.co;2-o.
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  - Dewhirst, M. W., B. Klitzman, R. D. Braun, D. M. Brizel, Z. A. Haroon, and T. W. Secomb. “Review of methods used to study oxygen transport at the microcirculatory level.” Int J Cancer 90, no. 5 (October 20, 2000): 237–55.
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  - Sundin, B. M., M. A. Hussein, S. Glasofer, M. H. El-Falaky, S. M. Abdel-Aleem, R. E. Sachse, and B. Klitzman. “The role of allopurinol and deferoxamine in preventing pressure ulcers in pigs.” Plast Reconstr Surg 105, no. 4 (April 2000): 1408–21. https://doi.org/10.1097/00006534-200004040-00021.
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  - Brown, S. A., A. J. Mayberry, J. A. Mathy, T. M. Phillips, B. Klitzman, and L. S. Levin. “The effect of muscle flap transposition to the fracture site on TNFalpha levels during fracture healing.” Plast Reconstr Surg 105, no. 3 (March 2000): 991–98. https://doi.org/10.1097/00006534-200003000-00023.
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  - Klitzman, B., R. D. Braun, A. C. Lockhart, L. Heller, M. W. Dewhirst, and H. I. Hurwitz. “Wound-induced angiogenesis: A clinical model.” Edited by K. Messmer. Orthogonal Polarization Spectral Imaging 24 (January 1, 2000): 110–14.
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  - Dewhirst, M. W., E. T. Ong, R. D. Braun, B. Smith, B. Klitzman, S. M. Evans, and D. Wilson. “Quantification of longitudinal tissue pO2 gradients in window chamber tumours: impact on tumour hypoxia.” Br J Cancer 79, no. 11–12 (April 1999): 1717–22. https://doi.org/10.1038/sj.bjc.6690273.
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  - Sachse, R. E., S. A. Fink, and B. Klitzman. “Multimodality evaluation of pressure relief surfaces.” Plast Reconstr Surg 102, no. 7 (December 1998): 2381–87. https://doi.org/10.1097/00006534-199812000-00017.
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  - Sachse, R. E., S. A. Fink, and B. Klitzman. “Comparison of supine and lateral positioning on various clinically used support surfaces.” Ann Plast Surg 41, no. 5 (November 1998): 513–18. https://doi.org/10.1097/00000637-199811000-00011.
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  - Klitzman, B., C. Kalinowski, S. L. Glasofer, and L. Rugani. “Pressure ulcers and pressure relief surfaces.” Clin Plast Surg 25, no. 3 (July 1998): 443–50.
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  - Ritter, E. F., J. C. Cronan, A. M. Rudner, D. Serafin, and B. Klitzman. “Improved microsurgical anastomotic patency with low molecular weight heparin.” J Reconstr Microsurg 14, no. 5 (July 1998): 331–36. https://doi.org/10.1055/s-2007-1000186.
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  - Sharkawy, A. A., B. Klitzman, G. A. Truskey, and W. M. Reichert. “Engineering the tissue which encapsulates subcutaneous implants. II. Plasma-tissue exchange properties.” J Biomed Mater Res 40, no. 4 (June 15, 1998): 586–97. https://doi.org/10.1002/(sici)1097-4636(19980615)40:4<586::aid-jbm10>3.0.co;2-e.
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  - Sharkawy, A. A., B. Klitzman, G. A. Truskey, and W. M. Reichert. “Engineering the tissue which encapsulates subcutaneous implants. III. Effective tissue response times.” J Biomed Mater Res 40, no. 4 (June 15, 1998): 598–605. https://doi.org/10.1002/(sici)1097-4636(19980615)40:4<598::aid-jbm11>3.0.co;2-c.
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  - Bhat, V. D., B. Klitzman, K. Koger, G. A. Truskey, and W. M. Reichert. “Improving endothelial cell adhesion to vascular graft surfaces: clinical need and strategies.” J Biomater Sci Polym Ed 9, no. 11 (1998): 1117–35. https://doi.org/10.1163/156856298x00686.
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  - Ritter, E. F., M. M. Fata, A. M. Rudner, and B. Klitzman. “Heparin bonding increases patency of long microvascular prostheses.” Plast Reconstr Surg 101, no. 1 (January 1998): 142–46. https://doi.org/10.1097/00006534-199801000-00023.
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  - Sharkawy, A. A., B. Klitzman, G. A. Truskey, and W. M. Reichert. “Engineering the tissue which encapsulates subcutaneous implants. I. Diffusion properties.” J Biomed Mater Res 37, no. 3 (December 5, 1997): 401–12. https://doi.org/10.1002/(sici)1097-4636(19971205)37:3<401::aid-jbm11>3.0.co;2-e.
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  - Ritter, E. F., Y. B. Kim, H. P. Reischl, D. Serafin, A. M. Rudner, and B. Klitzman. “Heparin coating of vascular prostheses reduces thromboemboli.” Surgery 122, no. 5 (November 1997): 888–92. https://doi.org/10.1016/s0039-6060(97)90329-9.
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  - Musselwhite, J. M., B. Klitzman, W. Maixner, and E. J. Burkes. “Laser Doppler flowmetry: a clinical test of pulpal vitality.” Oral Surg Oral Med Oral Pathol Oral Radiol Endod 84, no. 4 (October 1997): 411–19. https://doi.org/10.1016/s1079-2104(97)90041-x.
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  - Ritter, E. F., M. Axelrod, K. W. Minn, E. Eades, A. M. Rudner, D. Serafin, and B. Klitzman. “Modulation of ultraviolet light-induced epidermal damage: beneficial effects of tocopherol.” Plast Reconstr Surg 100, no. 4 (September 1997): 973–80. https://doi.org/10.1097/00006534-199709001-00021.
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  - Viscardi, P. J., E. A. Page, H. G. Clark, D. Serafin, and B. Klitzman. “Iloprost in alginate decreases the thrombogenicity of expanded polytetrafluoroethylene.” J Reconstr Microsurg 13, no. 4 (May 1997): 303–6. https://doi.org/10.1055/s-2007-1000240.
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  - Maynor, M. L., R. E. Moon, B. Klitzman, P. J. Fracica, and A. Canada. “Brown recluse spider envenomation: a prospective trial of hyperbaric oxygen therapy.” Acad Emerg Med 4, no. 3 (March 1997): 184–92. https://doi.org/10.1111/j.1553-2712.1997.tb03738.x.
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  - Sonntag, K. D., B. Klitzman, E. J. Burkes, J. Hoke, and J. Moshonov. “Pulpal response to cavity preparation with the Er:YAG and Mark III free electron lasers.” Oral Surg Oral Med Oral Pathol Oral Radiol Endod 81, no. 6 (June 1996): 695–702. https://doi.org/10.1016/s1079-2104(96)80076-x.
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  - Ritter, E. F., J. P. Anthony, L. S. Levin, C. P. Demas, B. Klitzman, D. Skarada, and D. Serafin. “Microsurgical composite tissue transplantation at difficult recipient sites facilitated by preliminary installation of vein grafts as arteriovenous loops.” J Reconstr Microsurg 12, no. 4 (May 1996): 231–40. https://doi.org/10.1055/s-2007-1006482.
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  - Zavitsanos, G., L. Huang, W. Panza, D. Serafin, and B. Klitzman. “Limiting impairment of muscle function following ischemia and reperfusion in rabbits.” J Reconstr Microsurg 12, no. 3 (April 1996): 183–87. https://doi.org/10.1055/s-2007-1006474.
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  - Zhang, J., A. D. Sam, B. Klitzman, and C. A. Piantadosi. “Inhibition of nitric oxide synthase on brain oxygenation in anesthetized rats exposed to hyperbaric oxygen.” Undersea Hyperb Med 22, no. 4 (December 1995): 377–82.
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  - Kimura, H., N. Z. Wu, R. Dodge, D. P. Spencer, B. M. Klitzman, T. M. McIntyre, and M. W. Dewhirst. “Inhibition of radiation-induced up-regulation of leukocyte adhesion to endothelial cells with the platelet-activating factor inhibitor, BN52021.” Int J Radiat Oncol Biol Phys 33, no. 3 (October 15, 1995): 627–33. https://doi.org/10.1016/0360-3016(95)00205-D.
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  - Skarada, D. J., G. R. Erickson, K. L. Warnecke, T. V. du Laney, C. S. Greenberg, E. F. Ritter, and B. Klitzman. “Assessments of thrombogenicity by three in vitro techniques. Student Research Award in the Undergraduate, Master Candidate, or Health Science Degree Candidate Category, 21st annual meeting of the Society for Biomaterials, San Francisco, CA, March 18-22, 1995.” J Biomed Mater Res 29, no. 9 (September 1995): 1039–45. https://doi.org/10.1002/jbm.820290903.
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  - Zhang, J., H. Benveniste, B. Klitzman, and C. A. Piantadosi. “Nitric oxide synthase inhibition and extracellular glutamate concentration after cerebral ischemia/reperfusion.” Stroke 26, no. 2 (February 1995): 298–304. https://doi.org/10.1161/01.str.26.2.298.
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  - Hoke, J. A., E. J. Burkes, J. T. White, M. B. Duffy, and B. Klitzman. “Blood-flow mapping of oral tissues by laser Doppler flowmetry.” Int J Oral Maxillofac Surg 23, no. 5 (October 1994): 312–15. https://doi.org/10.1016/s0901-5027(05)80117-1.
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  - Kim, Y. B., H. P. Reisch, D. Serafin, and B. Klitzman. “Evaluation of the thrombogenecity of microvascular prosthesis by in vivo microscopy.” J Korean Med Sci 9, no. 5 (October 1994): 357–61. https://doi.org/10.3346/jkms.1994.9.5.357.
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  - Wu, N. Z., B. A. Ross, C. Gulledge, B. Klitzman, R. Dodge, and M. W. Dewhirst. “Differences in leucocyte-endothelium interactions between normal and adenocarcinoma bearing tissues in response to radiation.” Br J Cancer 69, no. 5 (May 1994): 883–89. https://doi.org/10.1038/bjc.1994.171.
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  - Klitzman, B. “Rheology and the regulation of oxygen delivery.” Microsurgery 15, no. 6 (1994): 369–73. https://doi.org/10.1002/micr.1920150603.
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  - Peterseim, D. S., C. H. Meyers, D. M. Craig, J. S. Heinle, A. M. Jayawant, J. J. Devaney, B. M. Klitzman, and P. Van Trigt. “Enhanced cardiac preservation with oxygenated University of Wisconsin solution.” J Surg Res 55, no. 6 (December 1993): 588–94. https://doi.org/10.1006/jsre.1993.1189.
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  - Wu, N. Z., B. Klitzman, G. Rosner, D. Needham, and M. W. Dewhirst. “Measurement of material extravasation in microvascular networks using fluorescence video-microscopy.” Microvasc Res 46, no. 2 (September 1993): 231–53. https://doi.org/10.1006/mvre.1993.1049.
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  - Wigod, M. D., and B. Klitzman. “Quantification of in vitro endothelial cell adhesion to vascular graft material.” J Biomed Mater Res 27, no. 8 (August 1993): 1057–62. https://doi.org/10.1002/jbm.820270811.
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  - Feldman, D. L., R. S. Sepka, and B. Klitzman. “Tissue oxygenation and blood flow on specialized and conventional hospital beds.” Ann Plast Surg 30, no. 5 (May 1993): 441–44. https://doi.org/10.1097/00000637-199305000-00008.
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  - Vann, R. D., E. F. Ritter, M. D. Plunkett, C. W. Wyble, C. V. Bensen, W. A. Gerth, W. J. Barwick, and B. Klitzman. “Patency and blood flow in gas denucleated arterial prostheses.” J Biomed Mater Res 27, no. 4 (April 1993): 493–98. https://doi.org/10.1002/jbm.820270410.
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  - Secomb, T. W., R. Hsu, M. W. Dewhirst, B. Klitzman, and J. F. Gross. “Analysis of oxygen transport to tumor tissue by microvascular networks.” Int J Radiat Oncol Biol Phys 25, no. 3 (February 15, 1993): 481–89. https://doi.org/10.1016/0360-3016(93)90070-c.
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  - Brizel, D. M., B. Klitzman, J. M. Cook, J. Edwards, G. Rosner, and M. W. Dewhirst. “A comparison of tumor and normal tissue microvascular hematocrits and red cell fluxes in a rat window chamber model.” Int J Radiat Oncol Biol Phys 25, no. 2 (January 15, 1993): 269–76. https://doi.org/10.1016/0360-3016(93)90348-y.
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  - Dewhirst, M. W., D. Madwed, R. E. Meyer, E. T. Ong, B. Klitzman, G. L. Rosner, and R. Dodge. “Reduction in tumor blood flow in skin flap tumor after hydralazine is not due to a vascular steal phenomenon.” Radiation Oncology Investigations 1, no. 5 (January 1, 1993): 270–78. https://doi.org/10.1002/roi.2970010504.
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  - Dewhirst, M. W., E. T. Ong, D. Madwed, B. Klitzman, T. Secomb, D. Brizel, J. Bonaventura, G. Rosner, B. Kavanagh, and J. Edwards. “Effects of the calcium channel blocker flunarizine on the hemodynamics and oxygenation of tumor microvasculature.” Radiat Res 132, no. 1 (October 1992): 61–68.
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  - Wu, N. Z., B. Klitzman, R. Dodge, and M. W. Dewhirst. “Diminished leukocyte-endothelium interaction in tumor microvessels.” Cancer Res 52, no. 15 (August 1, 1992): 4265–68.
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  - Dewhirst, M. W., R. Z. Vinuya, E. T. Ong, B. Klitzman, G. Rosner, T. W. Secomb, and J. F. Gross. “Effects of bradykinin on the hemodynamics of tumor and granulating normal tissue microvasculature.” Radiat Res 130, no. 3 (June 1992): 345–54.
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  - Dewhirst, M. W., E. T. Ong, B. Klitzman, T. W. Secomb, R. Z. Vinuya, R. Dodge, D. Brizel, and J. F. Gross. “Perivascular oxygen tensions in a transplantable mammary tumor growing in a dorsal flap window chamber.” Radiat Res 130, no. 2 (May 1992): 171–82.
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  - Bensen, C. V., R. D. Vann, K. E. Koger, and B. Klitzman. “Quantification of gas denucleation and thrombogenicity of vascular grafts.” J Biomed Mater Res 25, no. 3 (March 1991): 373–86. https://doi.org/10.1002/jbm.820250309.
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  - Minn, K. W., D. Serafin, E. Mikat, and B. Klitzman. “Reconstruction of rat femoral veins with microvascular prostheses.” Plast Reconstr Surg 87, no. 3 (March 1991): 536–42. https://doi.org/10.1097/00006534-199103000-00022.
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  - Clinton, M. S., R. S. Sepka, D. Bristol, W. C. Pederson, W. J. Barwick, D. Serafin, and B. Klitzman. “Establishment of normal ranges of laser Doppler blood flow in autologous tissue transplants.” Plast Reconstr Surg 87, no. 2 (February 1991): 299–309. https://doi.org/10.1097/00006534-199102000-00012.
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  - Axelrod, M., D. Serafin, and B. Klitzman. “Ultraviolet light and free radicals: an immunologic theory of epidermal carcinogenesis.” Plast Reconstr Surg 86, no. 3 (September 1990): 582–93. https://doi.org/10.1097/00006534-199009000-00037.
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  - Goldberg, M., D. Serafin, and B. Klitzman. “Quantification of neutrophil adhesion to skeletal muscle venules following ischemia-reperfusion.” J Reconstr Microsurg 6, no. 3 (July 1990): 267–70. https://doi.org/10.1055/s-2007-1006829.
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  - Perona, B. P., J. V. Bartolome, R. S. Sepka, D. Serafin, and B. Klitzman. “Acute difluoromethylornithine treatment increases skin flap survival in rats.” Ann Plast Surg 25, no. 1 (July 1990): 26–28. https://doi.org/10.1097/00000637-199007000-00006.
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  - Eshbaugh, W. G., B. G. Forley, E. F. Ritter, D. Serafin, and B. Klitzman. “Stimulation of DNA synthesis in human epidermis by UVB radiation and its inhibition by difluoromethylornithine.” Plast Reconstr Surg 85, no. 4 (April 1990): 593–96. https://doi.org/10.1097/00006534-199004000-00015.
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  - Goldberg, J., R. S. Sepka, B. P. Perona, W. C. Pederson, and B. Klitzman. “Laser Doppler blood flow measurements of common cutaneous donor sites for reconstructive surgery.” Plast Reconstr Surg 85, no. 4 (April 1990): 581–86. https://doi.org/10.1097/00006534-199004000-00013.
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  - Burk, R. W., D. Serafin, and B. Klitzman. “Toxic effects of catecholamines on skin.” Plast Reconstr Surg 85, no. 1 (January 1990): 92–99. https://doi.org/10.1097/00006534-199001000-00016.
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  - Smith, Y. R., B. Klitzman, M. N. Ellis, and F. C. Kull. “The effect of nicotinamide on microvascular density and thermal injury in rats.” J Surg Res 47, no. 5 (November 1989): 465–69. https://doi.org/10.1016/0022-4804(89)90103-0.
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  - Ritter, E. F., R. D. Vann, C. Wyble, W. J. Barwick, and B. Klitzman. “Hydrostatic pressure reduces thrombogenicity of polytetrafluoroethylene vascular grafts.” Am J Physiol 257, no. 4 Pt 2 (October 1989): H1076–81. https://doi.org/10.1152/ajpheart.1989.257.4.H1076.
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  - Demas, C. P., R. Vann, E. Ritter, R. S. Sepka, B. Klitzman, and W. J. Barwick. “Decreased thrombogenicity of vascular prostheses following gas denucleation by hydrostatic pressure.” Plast Reconstr Surg 82, no. 6 (December 1988): 1042–45. https://doi.org/10.1097/00006534-198812000-00016.
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  - Gelman, J., J. V. Bartolome, S. Jenkins, D. Serafin, S. M. Schanberg, and B. Klitzman. “Reduced cell death in skin flaps in rats treated with difluoromethylornithine.” Faseb J 1, no. 6 (December 1987): 474–77. https://doi.org/10.1096/fasebj.1.6.3119414.
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  - Klitzman, B. “Microvascular determinants of blood flow.” J Reconstr Microsurg 4, no. 1 (October 1987): 77–80. https://doi.org/10.1055/s-2007-1006968.
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  - Huang, L., C. T. Privalle, D. Serafin, and B. Klitzman. “Increased survival of skin flaps by scavengers of superoxide radical.” Faseb J 1, no. 2 (August 1987): 129–32. https://doi.org/10.1096/fasebj.1.2.3038647.
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  - Jenkins, S. D., R. S. Sepka, W. J. Barwick, D. Serafin, and B. Klitzman. “Routine clinical use of laser Doppler flowmeter to monitor free tissue transfer: preliminary results.” J Reconstr Microsurg 3, no. 4 (July 1987): 281–83. https://doi.org/10.1055/s-2007-1006996.
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  - Fleming, B. P., B. Klitzman, and W. O. Johnson. “Measurement of erythrocyte velocity by use of a periodic differential detector.” Am J Physiol 249, no. 4 Pt 2 (October 1985): H899–905. https://doi.org/10.1152/ajpheart.1985.249.4.H899.
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  - Klitzman, B., and S. J. Fronczak. “Mitochondrial distribution in hamster cremaster muscle.” Adv Exp Med Biol 180 (1984): 695–700. https://doi.org/10.1007/978-1-4684-4895-5_68.
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  - Klitzman, B., A. S. Popel, and B. R. Duling. “Oxygen transport in resting and contracting hamster cremaster muscles: experimental and theoretical microvascular studies.” Microvasc Res 25, no. 1 (January 1983): 108–31. https://doi.org/10.1016/0026-2862(83)90047-x.
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  - Klitzman, B., D. N. Damon, R. J. Gorczynski, and B. R. Duling. “Augmented tissue oxygen supply during striated muscle contraction in the hamster. Relative contributions of capillary recruitment, functional dilation, and reduced tissue PO2.” Circ Res 51, no. 6 (December 1982): 711–21. https://doi.org/10.1161/01.res.51.6.711.
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  - Klitzman, B., and P. C. Johnson. “Capillary network geometry and red cell distribution in hamster cremaster muscle.” Am J Physiol 242, no. 2 (February 1982): H211–19. https://doi.org/10.1152/ajpheart.1982.242.2.H211.
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  - Duling, B. R., and B. Klitzman. “Local control of microvascular function: role in tissue oxygen supply.” Annu Rev Physiol 42 (1980): 373–82. https://doi.org/10.1146/annurev.ph.42.030180.002105.
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  - Klitzman, B., and B. R. Duling. “Microvascular hematocrit and red cell flow in resting and contracting striated muscle.” Am J Physiol 237, no. 4 (October 1979): H481–90. https://doi.org/10.1152/ajpheart.1979.237.4.H481.
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  - Gorczynski, R. J., B. Klitzman, and B. R. Duling. “Interrelations between contracting striated muscle and precapillary microvessels.” Am J Physiol 235, no. 5 (November 1978): H494–504. https://doi.org/10.1152/ajpheart.1978.235.5.H494.
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- Book Sections
  - Kasili, P. M., and T. Vo-Dinh. “Monitoring apoptosis and anticancer drug activity in single cells using nanosensors.” In Nanotechnology in Biology and Medicine: Methods, Devices, and Applications, Second Edition, 423–38, 2017. https://doi.org/10.4324/9781315374581.
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  - Cho, E. H., A. Boico, N. A. Wisniewski, R. Gant, K. L. Helton, N. L. Brown, J. K. Register, T. Vo-Dinh, T. Schroeder, and B. Klitzman. “Micovascular integration into porous polyHEMA scaffold,” Vol. 8958, 2014. https://doi.org/10.1117/12.2037950.
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- Other Articles
  - Olbrich, K. C., R. A. Meade, W. Bruno, B. M. Sundin, L. Heller, D. Erdmann, L. S. Levin, and B. Klitzman. “Tempostatin™ (halofuginone) inhibits collagen deposition in fibrous capsules.” Transactions 7th World Biomaterials Congress, December 1, 2004.
  - Erdmann, D., and B. Klitzman. “Investigation of TRAM flap oxygenation and perfusion by near-infrared reflection spectroscopy and color-coded duplex sonography: Discussion.” Plastic and Reconstructive Surgery, January 1, 2004. https://doi.org/10.1097/01.PRS.0000100154.62985.59.
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  - Duncan, G. T., A. C. Lockhart, J. R. Ross, B. Klitzman, K. Olbrich, V. M. Lee, A. D. Proia, and H. I. Hurwitz. “Wound angiogenesis in healthy volunteers using OPSI technology: A potential surrogate marker for antiangiogenesis agents.” Clinical Cancer Research. AMER ASSOC CANCER RESEARCH, November 1, 2001.
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  - Wisniewski, N., N. Rajamand, W. Reichert, B. Klitzman, and U. Ungerstedt. “Metabolites at a biomaterial-tissue interface sampled by microdialysis - a comparison of the subcutaneous foreign body response in humans and rats over 8 days.” Annals of Biomedical Engineering, December 1, 2000.
  - Wisniewski, Natalie, Neda Rajamand, William Reichert, Bruce Klitzman, and Urban Ungerstedt. “Metabolites at a biomaterial-tissue interface sampled by microdialysis - a comparison of the subcutaneous foreign body response in humans and rats over 8 days.” Annals of Biomedical Engineering, 2000.
  - Wisniewski, N., B. Miller, B. Klitzman, and M. Reichert. “Characterization of analyte transport over time through implantable biosensor membranes using microdialysis.” Annual International Conference of the Ieee Engineering in Medicine and Biology Proceedings, December 1, 1999.
  - Molenaar, A. “Modulation of ultraviolet light-induced epidermal damage: beneficial effects of tocopherol.” Plast Reconstr Surg, October 1998. https://doi.org/10.1097/00006534-199810000-00113.
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  - Koger, K. E., L. S. Levin, and B. Klitzman. “Effects of internal pressure on blood flow in pig skin.” Faseb Journal, 1998.
  - Wisniewski, N., B. Klitzman, and W. M. Reichert. “Membrane biofouling measured by microdialysis.” Proceedings of the Controlled Release Society, January 1, 1998.
  - Sharkawy, A., B. Klitzman, G. Truskey, and W. Reichert. “Diffusion properties of tissue which encapsulates subcutaneous implants.” Polymeric Materials Science and Engineering, Proceedings of the Acs Division of Polymeric Materials Science and Engineering, January 1, 1997.
  - Laney, T. V. du, G. A. Truskey, and B. Klitzman. “Fibronectin enhances cell spreading and retention on ePTFE under shear in vitro.” Transactions of the Annual Meeting of the Society for Biomaterials in Conjunction With the International Biomaterials Symposium, December 1, 1996.
  - Sharkawy, A. A., B. Klitzman, G. A. Truskey, and W. M. Reichert. “Diffusion properties of capsular tissue.” Transactions of the Annual Meeting of the Society for Biomaterials in Conjunction With the International Biomaterials Symposium, December 1, 1996.
  - Skarada, D. J., T. V. du Laney, T. M. Steele, E. F. Ritter, and B. Klitzman. “Continual in vivo assessment of 1 mm diameter vascular prostheses.” Transactions of the Annual Meeting of the Society for Biomaterials in Conjunction With the International Biomaterials Symposium, December 1, 1996.
  - SONNTAG, K., E. J. BURKES, J. HOKE, and B. KLITZMAN. “PULPAL RESPONSE TO CAVITY PREPARATION WITH THE ERYAG LASER.” Journal of Dental Research. AMER ASSOC DENTAL RESEARCH, January 1, 1995.
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  - RITTER, E., R. VANN, R. SEPKA, and B. KLITZMAN. “REDUCTION IN THROMBOGENICITY OF MICROVASCULAR PROSTHESES.” Faseb Journal. FEDERATION AMER SOC EXP BIOL, March 25, 1988.
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  - Forley, B. G., L. Huang, J. Bartolome, D. Serafin, and B. Klitzman. “The potential role of polyamine inhibition in keloid therapy.” Surgical Forum, January 1, 1988.
  - KLITZMAN, B., J. GELMAN, D. SERAFIN, R. SEPKA, S. SCHANBERG, and J. V. BARTOLOME. “PROTECTION OF RAT SKIN AGAINST ISCHEMIC DAMAGE WITH DIFLUOROMETHYLORNITHINE.” Federation Proceedings. FEDERATION AMER SOC EXP BIOL, March 5, 1987.
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  - KLITZMAN, B., N. SCHRADER, R. SEPKA, and D. SERAFIN. “RELATIVE EFFECTS OF RED-CELLS AND PLATELETS ON RAT SKIN FLAP SURVIVAL.” Federation Proceedings. FEDERATION AMER SOC EXP BIOL, March 5, 1987.
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  - Ball, R., D. Serafin, and B. Klitzman. “Rat skin flap necrosis reduced with topical chlorpromazine.” Surgical Forum, January 1, 1987.
  - KLITZMAN, B., R. S. SEPKA, and D. SERAFIN. “EFFECTS OF SYSTEMIC HEMATOCRIT ON RAT SKIN FLAP SURVIVAL.” Biorheology. PERGAMON-ELSEVIER SCIENCE LTD, January 1, 1986.
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  - KLITZMAN, B. “RELATIVE INCREASE IN CAPILLARY HEMATOCRIT FOLLOWING ISOVOLEMIC HEMODILUTION.” Microvascular Research. ACADEMIC PRESS INC JNL-COMP SUBSCRIPTIONS, January 1, 1985.
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  - FLEMING, B. P., B. KLITZMAN, and W. O. JOHNSON. “A PERIODIC DIFFERENTIAL DETECTOR FOR MICROVASCULAR VELOCIMETRY.” International Journal of Microcirculation Clinical and Experimental. KARGER, January 1, 1984.
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  - FLEMING, B. P., B. KLITZMAN, and W. O. JOHNSON. “A PERIODIC DIFFERENTIAL DETECTOR FOR MICROVASCULAR VELOCIMETRY.” Microvascular Research. ACADEMIC PRESS INC JNL-COMP SUBSCRIPTIONS, January 1, 1984.
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  - KLITZMAN, B. “RELATIVE VELOCITY OF RED-CELLS AND SUB-MICRON PARTICLES IN MUSCLE CAPILLARIES.” International Journal of Microcirculation Clinical and Experimental. KARGER, January 1, 1984.
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  - KLITZMAN, B. “EFFECT OF FLUORESCENT LABELING OF RED-CELLS ON FLOW THROUGH CAPILLARIES.” Microvascular Research. ACADEMIC PRESS INC JNL-COMP SUBSCRIPTIONS, January 1, 1983.
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  - KLITZMAN, B., and P. C. JOHNSON. “FACTORS AFFECTING THE DISTRIBUTION OF RED-BLOOD-CELLS AT CAPILLARY BIFURCATIONS.” Microvascular Research. ACADEMIC PRESS INC JNL-COMP SUBSCRIPTIONS, January 1, 1981.
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  - KLITZMAN, B., and P. C. JOHNSON. “HETEROGENEITY OF RED-CELL FLUX AND CAPILLARY HEMATOCRIT IN STRIATED-MUSCLE CAPILLARIES.” Microvascular Research. ACADEMIC PRESS INC JNL-COMP SUBSCRIPTIONS, January 1, 1980.
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  - KLITZMAN, B., and B. R. DULING. “CAUSES OF LOW MICRO-VASCULAR HEMATOCRIT IN HAMSTER CREMASTER CAPILLARIES.” Microvascular Research. ACADEMIC PRESS INC JNL-COMP SUBSCRIPTIONS, January 1, 1979.
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  - KLITZMAN, B., and B. R. DULING. “ACUTE HEMATOCRIT CHANGES IN CAPILLARIES OF STRIATED-MUSCLE DURING FUNCTIONAL HYPEREMIA.” Microvascular Research. ACADEMIC PRESS INC JNL-COMP SUBSCRIPTIONS, January 1, 1978.
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  - Klitzman, B., and B. R. Duling. “Effects of oxygen and norepinephrine (NE) on capillary blood flow in contracting muscle.” Federation Proceedings, January 1, 1977.
- Conference Papers
  - Bottenus, N., T. Straube, S. Farling, T. Vesel, B. Klitzman, M. A. Deshusses, and I. M. Cheifetz. “Ultrasonic bubble detection and tracking using spatial coherence and motion modeling.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 11602, 2021. https://doi.org/10.1117/12.2580587.
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  - Patel, Preet, Mahmoud Ibrahim, Ryan Schweller, Bruce Klitzman, and Mohamid Ibrahim. “NOVEL IMPLANTABLE BIOSENSORS FOR LIFETIME-BASED MONITORING OF OXYGENATION TO PREDICT WOUND HEALING.” In Wound Repair and Regeneration, 27:A19–A19. WILEY, 2019.
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  - Wang, H. N., J. K. Register, A. M. Fales, N. Gandra, P. Strobbia, E. H. Cho, A. Boico, G. M. Palmer, B. Klitzman, and T. Vo-Dinh. “Implantable "smart tattoo" SERS nanosensors for in vivo detection of nucleic acid biotargets in a large animal model.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 10894, 2019. https://doi.org/10.1117/12.2514634.
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  - Ibrahim, Mohamed M., Jennifer S. Chien, Mahmoud M. Mohammed, Timothy King, and Bruce Klitzman. “Detection of Acute Vascular Occlusion Using Oxygen Monitoring in Myocutaneous Flaps.” In Wound Repair and Regeneration, 26:A15–A15. WILEY, 2018.
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  - Ibrahim, Mohamed M., Ryan M. Schweller, Mahmoud M. Mohammed, David B. Powers, and Bruce Klitzman. “Implantable Oxygen Platform for Continuous, Real-time Detection of Vascular Perfusion and Ischemia.” In Wound Repair and Regeneration, 26:A8–A8. WILEY, 2018.
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  - Ibrahim, Mohamed M., Hysem Eldik, Mahmoud M. Mohammed, Zi Jun Wu, and Bruce Klitzman. “COMPARISON OF INTRADERMAL AND SUBCUTANEOUS TISSUE OXYGEN TENSION MONITOR TO DETECT FLAP COMPROMISE.” In Wound Repair and Regeneration, 25:A40–A40. WILEY, 2017.
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  - Ibrahim, Mohamed M., Jennifer S. Chien, Mahmoud M. Mohammed, Timothy King, and Bruce Klitzman. “RAPID DETECTION OF ACUTE VASCULAR OCCLUSION USING OXYGEN MONITORING IN A RAT MYOCUTANEOUS FLAP MODEL.” In Wound Repair and Regeneration, 25:A40–A40. WILEY, 2017.
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  - Ibrahim, Mohamed M., Ryan M. Schweller, Mahmoud M. Mohammed, David B. Powers, and Bruce Klitzman. “NOVEL IMPLANTABLE OXYGEN BIOSENSORS FOR DETECTION OF VASCULAR PERFUSION AND ISCHEMIA.” In Wound Repair and Regeneration, 25:A40–A40. WILEY, 2017.
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  - Chien, J., M. Mohammed, H. Eldik, M. Ibrahim, S. Nichols, and B. Klitzman. “Implantable Oxygen Biosensors Reveals Post-occlusion Tissue Reactive Hyperoxia.” In Journal of Vascular Research, 54:37–38. KARGER, 2017.
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  - Shammas, Ronnie L., Andrew M. Fales, Bridget M. Crawford, Bruce Klitzman, Scott T. Hollenbeck, and Tuan VoDinh. “Plasmonic Gold-Nanostars for Tracking of Adult Stem Cells and for Selective Photothermal Ablation.” In Journal of the American College of Surgeons, 223:S100–S100. Ovid Technologies (Wolters Kluwer Health), 2016. https://doi.org/10.1016/j.jamcollsurg.2016.06.204.
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  - Eldik, H., B. Klitzman, M. Ibrahim, J. Martinez, S. Nichols, and N. Wisniewksi. “548 Real-time continuous monitoring of subcutaneous tissue oxygenation.” In Journal of Investigative Dermatology, 136:S254–S254. Elsevier BV, 2016. https://doi.org/10.1016/j.jid.2016.06.572.
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  - Eldik, H., M. Mohamed, J. Martinez, N. Wisiniewski, S. Nichols, and B. Klitzman. “LB823 Real-time continuous monitoring of tissue oxygenation: Quantifying critically ischemic flap regions.” In Journal of Investigative Dermatology, 136:B13–B13. Elsevier BV, 2016. https://doi.org/10.1016/j.jid.2016.05.082.
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  - Ibrahim, Mohamed, Vrad Levering, Eileen Lanham, James Parra, Harold Leraas, Gabriel Lopez, Bruce Klitzman, Andrew Peterson, and Howard Levinson. “MP24-17 PERVASIVE BIOFILM COVERAGE: AN ANALYSIS OF BIOFILM FORMATION IN INDWELLING URINARY CATHETERS.” In Journal of Urology, Vol. 195. Ovid Technologies (Wolters Kluwer Health), 2016. https://doi.org/10.1016/j.juro.2016.02.773.
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  - Gastrell, P., J. Cho, and B. Klitzman. “Improving the Biocompatibility of Implants in Irradiated Tissue Using an Adipose-Derived Stromal-Vascular Fraction.” In International Journal of Radiation Oncology*Biology*Physics, 93:E544–45. Elsevier BV, 2015. https://doi.org/10.1016/j.ijrobp.2015.07.1941.
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  - Ibrahim, Mohamed M., Zi Jun Wu, and Bruce Klitzman. “Novel implantable optical oxygen monitor to detect flap viability.” In Journal of the American College of Surgeons, 221:e87–88. Ovid Technologies (Wolters Kluwer Health), 2015. https://doi.org/10.1016/j.jamcollsurg.2015.08.128.
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  - Jung, Y., H. Ji, Z. Chen, H. Chan, L. Atchison, B. Klitzman, G. Truskey, and K. W. Leong. “Fabrication of Scaffold-free Tissue Engineered Blood Vessel using Nanopatterned Human Mesenchymal Stem Cell Sheet.” In Tissue Engineering Part A, 21:S271–S271. MARY ANN LIEBERT, INC, 2015.
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  - Gastrell, Philip, Jinny Cho, and Bruce Klitzman. “472. Low-Shear Sodding of an Implantable Expanded Polytetrafluoroethylene Scaffold with a Rat Adipose-Derived Stromal-Vascular Fraction.” In Molecular Therapy, 23:S187–S187. Elsevier BV, 2015. https://doi.org/10.1016/s1525-0016(16)34081-3.
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  - Gastrell, Philip, Jinny Cho, and Bruce Klitzman. “Low-shear Sodding of an Implantable Expanded Polytetrafluoroethylene Scaffold with a Rat Adipose-derived Stromal-vascular Fraction.” In Faseb Journal, Vol. 29, 2015.
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  - Boico, Alina, Eugenia Cho, Lynne Liao, Janna Register, Andrew Fales, Natalie Wisnewski, Sulolit Pradhan, Tuan Vo-Dihn, Gregory Palmer, and Bruce Klitzman. “Characterization of Inflammatory Cell Response to Implanted Porous P-HEMA in the Dermis Vs Subcutaneous Tissue.” In Faseb Journal, Vol. 29. FEDERATION AMER SOC EXP BIOL, 2015.
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  - Liao, Lin, Eugenia Cho, Alina Boico, Janna Register, Andrew Fales, Kristen Helton, Natalie Wisniewski, Tuan Vo-Dinh, Gregory Palmer, and Bruce Klitzman. “Vascularization of Porous PolyHEMA Scaffolds.” In Faseb Journal, Vol. 29. FEDERATION AMER SOC EXP BIOL, 2015.
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  - Ibrahim, M. M., M. A. Medina, J. Bond, A. Bergeron, L. Chen, C. Quiles, G. Kokosis, et al. “FOREIGN BODY RESPONSE TO FIVE COMMON SUBCUTANEOUS IMPLANTS.” In Wound Repair and Regeneration, 23:A27–A27. WILEY-BLACKWELL, 2015.
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  - Ibrahim, M. M., Z. Wu, and B. Klitzman. “NOVEL IMPLANTABLE OPTICAL OXYGEN MONITOR TO DETECT FLAP VIABILITY.” In Wound Repair and Regeneration, 23:A26–A26. WILEY-BLACKWELL, 2015.
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  - Cho, Eugenia, Alina Boico, Nga Brown, Natalie Wisniewski, Kristen Helton, Janna Register, Andrew Fales, et al. “Tissue integration of porous polyHEMA scaffold.” In Faseb Journal, Vol. 28. FEDERATION AMER SOC EXP BIOL, 2014.
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  - Ibrahim, Mohamed M., Jennifer Bond, Andrew Bergeron, Kyle J. Miller, Tosan Ehanire, Carlos Quiles, Mark Fisher, et al. “Abstract 34: a novel immune competent murine hypertrophic scar contracture model: a tool to elucidate disease mechanism and develop new therapies.” In Plast Reconstr Surg, 133:44–45, 2014. https://doi.org/10.1097/01.prs.0000445067.48096.d1.
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  - Cho, Eugenia H., Alina Boico, Natalie A. Wisniewski, Kristen L. Helton, Janna K. Register, Andrew M. Fales, Gregory M. Palmer, Tuan Vo-Dinh, Thies Schroeder, and Bruce Klitzman. “Abstract 88: microvascular integration into versatile tissue engineering platforms.” In Plast Reconstr Surg, 133:102, 2014. https://doi.org/10.1097/01.prs.0000445121.15610.63.
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  - Schroeder, Thies, Natalie Wisniewski, Alina Boico, Nga Le, Eugenia Cho, Kristen Helton, Rebecca Gant, and Bruce Klitzman. “Long-term tissue integration of porous biopolymers as a material platform for metabolic biosensor.” In Faseb Journal, Vol. 26. FEDERATION AMER SOC EXP BIOL, 2012.
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  - Schroeder, Thies, Natalie Wisniewski, Alina Boico, Nga Le, Eugenia Cho, Kristen Helton, Rebecca Gant, and Bruce Klitzman. “Long-term tissue integration of porous biopolymers as a material platform for metabolic biosensor.” In Faseb Journal, Vol. 24, 2010.
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  - Prichard, H. L., W. M. Reichert, and B. Klitzman. “Adipose stem cell attachment to glucose sensors.” In 8th World Biomaterials Congress 2008, 4:2099, 2008.
  - Levinson, Howard, Blaine Mischen, Bruce Klitzman, Detlev Erdmann, and Scott L. Levin. “Non muscle myosin II regulates contractile phenotypes.” In Journal of the American College of Surgeons, 205:S60–61. Ovid Technologies (Wolters Kluwer Health), 2007. https://doi.org/10.1016/j.jamcollsurg.2007.06.148.
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  - Kondo, Y., S. I. Ahmad, R. M. Lee, S. Asrani, K. C. Olbrich, R. R. Allingham, and B. Klitzman. “Outflow facility of a Glaucoma Valve enclosed in expanded polytetrafluoroethylene (ePTFE).” In Investigative Ophthalmology & Visual Science, Vol. 46. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2005.
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  - Erdmann, D., C. Heitmann, K. C. M. Pu, K. Olbrich, L. S. Levin, and B. Klitzman. “Anastomoses for vascular shunt, arterial graft, and flap vascularization performed using magnets.” In Journal of the American College of Surgeons, 199:S64–S64. ELSEVIER SCIENCE INC, 2004.
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  - Schoenfisch, M. H., B. J. Nablo, M. E. Robbins, R. D. Butler, and B. Klitzman. “Nitric oxide release as a means for improving the tissue-compatibility of in vivo subcutaneous glucose biosensors.” In Abstracts of Papers of the American Chemical Society, 228:U159–60. AMER CHEMICAL SOC, 2004.
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  - Dai, Q. S., J. H. Huang, B. Klitzman, J. Rokovich, E. Rebar, B. Johnstone, C. Kontos, and B. Annex. “A genetically engineered plasmid encoding a zinc finger VEGF-activating transcription factor induces angiogenesis in the rabbits with hind-limb ischemia.” In Molecular Therapy, 7:S330–31. ACADEMIC PRESS INC ELSEVIER SCIENCE, 2003.
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  - Klitzman, B., R. N. Sweis, and K. C. Olbrich. “Chronic percutaneous intravital microscopy using orthogonal polarization spectral imaging.” In Faseb Journal, 15:A53–A53. FEDERATION AMER SOC EXP BIOL, 2001.
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  - Brown, S. A., T. M. Phillips, J. Mathy, B. Klitzman, and L. S. Levin. “IL-8 levels in infected bone marrow are modulated by a muscle flap.” In Faseb Journal, 14:A177–A177. FEDERATION AMER SOC EXP BIOL, 2000.
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  - Lockhart, A. C., R. D. Braun, M. W. Dewhirst, J. S. Humphrey, F. Yuan, J. Grichnick, A. Proia, D. Conway, B. Klitzman, and H. I. Hurwitz. “Wound angiogenesis inhibition as a marker for anti-angiogenic efficacy.” In Faseb Journal, 14:A35–A35. FEDERATION AMER SOC EXP BIOL, 2000.
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  - Olbrich, K. C., A. G. Ravin, A. L. Usala, L. S. Levin, and B. Klitzman. “Vascular density and capsule thickness around implanted devices.” In Faseb Journal, 14:A445–A445. FEDERATION AMER SOC EXP BIOL, 2000.
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  - Brown, S. A., T. Phillips, A. J. Mayberry, J. A. Mathy, B. Klitzman, and L. S. Levin. “The effect of Staph. aureus on TNFa and IFNg levels during wound healing in a canine open fracture model.” In Faseb Journal, 13:A852–A852. FEDERATION AMER SOC EXP BIOL, 1999.
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  - Moore, F. M., L. S. Levin, B. Klitzman, and S. A. Brown. “A new wound model for the study of acute soft tissue injury using microdialysis.” In Faseb Journal, 13:A678–A678. FEDERATION AMER SOC EXP BIOL, 1999.
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  - HUSSEIN, M., S. ABDELALEEM, M. ELFALAKY, D. SERAFIN, and B. KLITZMAN. “CORRELATION BETWEEN SKELETAL-MUSCLE HIGH-ENERGY ADENINE-NUCLEOTIDE CONTENT AND APPLIED PRESSURE.” In Faseb Journal, 9:A693–A693. FEDERATION AMER SOC EXP BIOL, 1995.
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  - KLITZMAN, B., N. SCHRADER, R. E. MCLENDON, and M. W. DEWHIRST. “QUANTITATIVE MORPHOLOGY OF RAT CARCINOMA WITH RELEVANCE TO OXYGENATION.” In Faseb Journal, 8:A1046–A1046. FEDERATION AMER SOC EXP BIOL, 1994.
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  - SONNY, M., A. D. SAM, C. A. PIANTADOSI, and B. KLITZMAN. “EFFECTS OF HYPERBARIC-OXYGEN ON ARTERIOLAR DIAMETER IN RAT CREMASTER MUSCLE.” In Faseb Journal, 7:A557–A557. FEDERATION AMER SOC EXP BIOL, 1993.
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  - SAM, A. D., M. SONNY, C. A. PIANTADOSI, and B. KLITZMAN. “EFFECT OF HYPERBARIC-OXYGEN ON MUSCLE OXYGEN-TENSIONS.” In Faseb Journal, 7:A449–A449. FEDERATION AMER SOC EXP BIOL, 1993.
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  - WIGOD, M., and B. KLITZMAN. “INCREASED MICROVASCULAR ENDOTHELIAL-CELL ADHESION TO BIOMATERIALS.” In Faseb Journal, 7:A241–A241. FEDERATION AMER SOC EXP BIOL, 1993.
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  - SECOMB, T. W., R. HSU, M. W. DEWHIRST, B. KLITZMAN, and J. F. GROSS. “SIMULATION OF OXYGEN-TRANSPORT TO TUMOR-TISSUE BY MICROVASCULAR NETWORKS.” In Faseb Journal, 6:A2084–A2084. FEDERATION AMER SOC EXP BIOL, 1992.
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  - HOKE, J., J. BURKES, J. WHITE, and B. KLITZMAN. “EFFECTS OF HARD AND RESILIENT DENTURE MATERIALS ON TISSUE PERFUSION.” In Journal of Dental Research, 69:228–228. AMER ASSOC DENTAL RESEARCH, 1990.
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  - Klitzman, B. “Regional variations of laser doppler blood flow in ischemic skin flaps.” In Plastic and Reconstructive Surgery, 86:327–28, 1990. https://doi.org/10.1097/00006534-199008000-00022.
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  - KLITZMAN, B., N. SCHRADER, and P. ELIZALDE. “INCREASES IN PERFUSED CAPILLARY DENSITY, CAPILLARY HEMATOCRIT AND SYSTEMIC HEMATOCRIT INDUCED BY CHRONIC EXPOSURE TO HYPOXIA OR COLD.” In Faseb Journal, 2:A1870–A1870. FEDERATION AMER SOC EXP BIOL, 1988.
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  - PERONA, B., M. CLINTON, and B. KLITZMAN. “INVIVO PLATELET-AGGREGATION IN THE MICROVASCULATURE FOLLOWING ULTRASONIC STIMULATION.” In Faseb Journal, 2:A1876–A1876. FEDERATION AMER SOC EXP BIOL, 1988.
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  - KLITZMAN, B., J. MYERS, R. P. WATTS, and P. C. JOHNSON. “MEASUREMENT OF MICRO-VASCULAR HEMATOCRIT AND RED-CELL VELOCITY USING STROBOSCOPIC EPI-FLUORESCENCE MICROSCOPY.” In Federation Proceedings, 41:1759–1759. FEDERATION AMER SOC EXP BIOL, 1982.
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  - KLITZMAN, B., and B. R. DULING. “EFFECTS OF OXYGEN AND NOREPINEPHRINE (NE) ON CAPILLARY BLOOD-FLOW IN CONTRACTING MUSCLE.” In Federation Proceedings, 36:451–451. FEDERATION AMER SOC EXP BIOL, 1977.
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Artistic Works & Non-Print Media
- Musical Performances
  - City Trees by Michael Markowski. Musician. 2017
  - Duke Medicine Orchestra Concert. Musician. 2016
  - Duke Medicine Orchestra. Musician. 2015
Teaching & Mentoring
Recent Courses
- BES 301B: Research in BES 2022
- CELLBIO 493: Research Independent Study 2022
- BES 301B: Research in BES 2021
- CELLBIO 493: Research Independent Study 2021
- BES 301B: Research in BES 2020
- CELLBIO 493: Research Independent Study 2020
Advising & Mentoring
- I have mentored over 31 post-doctoral fellows, served on over 42 thesis committees, and over 45 medical students in their research. In addition, I serve on the Third Year Committee to oversee the mandatory full year of medical student research. I am also a member of the Medical Student Promotions Committee.
  
  Advising undergraduate students in Design. Mentoring two teams of 5 students each solving a complex problem in research.
Available to mentor:
- Faculty
- Fellow
- Masters
- PhD
- Post-Doc
- Professional
- Resident
- Undergraduate
Teaching Activities
- Lecturing on Vascular Physiology to First Year Medical Students; 1986-present
  Co-Director, Biodesign, Biomedical Engineering, 2015-6
Scholarly, Clinical, & Service Activities
Presentations & Appearances
- Development of an erasable tattoo ink. First International Conference on Tattoo Safety. Bundesinstitut fur Risikobewertung. June 2013 2013
Service to the Profession
- President. The Microcirculatory Society. 1998 - 1999 1998 - 1999
Service to Duke
Academic & Administrative Activities
- Founder, MD/MEng dual degree program at Duke University, 2017
Clinical Activities
- Director, Tissue Viability Service, Duke University Hospital, 1988-2003

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Education, Training, & Certifications

Previous Appointments & Affiliations

Leadership & Clinical Positions at Duke

Academic Positions Outside Duke

In the News

Awards & Honors

Selected Grants

External Relationships

Selected Publications

Academic Articles

Book Sections

Other Articles

Conference Papers

Artistic Works & Non-Print Media

Musical Performances

Recent Courses

Advising & Mentoring

Available to mentor:

Teaching Activities

Presentations & Appearances

Service to the Profession

Service to Duke

Academic & Administrative Activities

Clinical Activities