Metabolites at a biomaterial-tissue interface sampled by microdialysis - a comparison of the subcutaneous foreign body response in humans and rats over 8 days
Publication
, Other
Wisniewski, N; Rajamand, N; Reichert, W; Klitzman, B; Ungerstedt, U
Published in: Annals of Biomedical Engineering
2000
The purpose of this work was to study how closely the rat models the human subcutaneous (SQ) foreign body response. Polyamide microdialysis probes (CMA/Microdialysis; Solna, Sweden) were implanted subcutaneously in healthy human volunteers and in Sprague Dawley rats (n = 12 probes per group). Microdialysis samples were collected over 8 days and analyzed for glucose, lactate, pyruvate and glycerol content. Correpsonding blood samples were analyzed. Results showed significant differences in the microdialysate concentrations and 8 day trends in humans in rats.
Duke Scholars
Published In
Annals of Biomedical Engineering
Publication Date
2000
Volume
28
Issue
SUPPL 1
Start / End Page
19
Location
Washington, WA, USA
Related Subject Headings
- Biomedical Engineering
- 11 Medical and Health Sciences
- 09 Engineering
Citation
APA
Chicago
ICMJE
MLA
NLM
Wisniewski, N., Rajamand, N., Reichert, W., Klitzman, B., & Ungerstedt, U. (2000). Metabolites at a biomaterial-tissue interface sampled by microdialysis - a comparison of the subcutaneous foreign body response in humans and rats over 8 days. Annals of Biomedical Engineering. Washington, WA, USA.
Wisniewski, Natalie, Neda Rajamand, William Reichert, Bruce Klitzman, and Urban Ungerstedt. “Metabolites at a biomaterial-tissue interface sampled by microdialysis - a comparison of the subcutaneous foreign body response in humans and rats over 8 days.” Annals of Biomedical Engineering, 2000.
Wisniewski N, Rajamand N, Reichert W, Klitzman B, Ungerstedt U. Metabolites at a biomaterial-tissue interface sampled by microdialysis - a comparison of the subcutaneous foreign body response in humans and rats over 8 days. Vol. 28, Annals of Biomedical Engineering. 2000. p. 19.
Wisniewski, Natalie, et al. “Metabolites at a biomaterial-tissue interface sampled by microdialysis - a comparison of the subcutaneous foreign body response in humans and rats over 8 days.” Annals of Biomedical Engineering, vol. 28, no. SUPPL 1, 2000, p. 19.
Wisniewski N, Rajamand N, Reichert W, Klitzman B, Ungerstedt U. Metabolites at a biomaterial-tissue interface sampled by microdialysis - a comparison of the subcutaneous foreign body response in humans and rats over 8 days. Annals of Biomedical Engineering. 2000. p. 19.
Published In
Annals of Biomedical Engineering
Publication Date
2000
Volume
28
Issue
SUPPL 1
Start / End Page
19
Location
Washington, WA, USA
Related Subject Headings
- Biomedical Engineering
- 11 Medical and Health Sciences
- 09 Engineering