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Cluster analysis of BI-RADS™ descriptions of biopsy-proven breast lesions

Publication ,  Journal Article
Markey, MK; Lo, JY; Tourassi, GD; Floyd, CE
Published in: Proceedings of SPIE - The International Society for Optical Engineering
January 1, 2002

The purpose of this study was to identify and characterize clusters in a heterogeneous breast cancer computer-aided diagnosis database. Identification of subgroups within the database could help elucidate clinical trends and facilitate future model building. Agglomerative hierarchical clustering and k-means clustering were used to identify clusters in a large, heterogeneous computer-aided diagnosis database based on mammographic findings (BI-RADS™) and patient age. The clusters were examined in terms of their feature distributions. The clusters showed logical separation of distinct clinical subtypes such as architectural distortions, masses, and calcifications. Moreover, the common subtypes of masses and calcifications were stratified into clusters based on age groupings. The percent of the cases that were malignant was notably different among the clusters. Cluster analysis can provide a powerful tool in discerning the subgroups present in a large, heterogeneous computer-aided diagnosis database.

Duke Scholars

Published In

Proceedings of SPIE - The International Society for Optical Engineering

DOI

ISSN

0277-786X

Publication Date

January 1, 2002

Volume

4684 I

Start / End Page

363 / 370

Related Subject Headings

  • 5102 Atomic, molecular and optical physics
  • 4009 Electronics, sensors and digital hardware
  • 4006 Communications engineering
 

Citation

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Markey, M. K., Lo, J. Y., Tourassi, G. D., & Floyd, C. E. (2002). Cluster analysis of BI-RADS™ descriptions of biopsy-proven breast lesions. Proceedings of SPIE - The International Society for Optical Engineering, 4684 I, 363–370. https://doi.org/10.1117/12.467177
Markey, M. K., J. Y. Lo, G. D. Tourassi, and C. E. Floyd. “Cluster analysis of BI-RADS™ descriptions of biopsy-proven breast lesions.” Proceedings of SPIE - The International Society for Optical Engineering 4684 I (January 1, 2002): 363–70. https://doi.org/10.1117/12.467177.
Markey MK, Lo JY, Tourassi GD, Floyd CE. Cluster analysis of BI-RADS™ descriptions of biopsy-proven breast lesions. Proceedings of SPIE - The International Society for Optical Engineering. 2002 Jan 1;4684 I:363–70.
Markey, M. K., et al. “Cluster analysis of BI-RADS™ descriptions of biopsy-proven breast lesions.” Proceedings of SPIE - The International Society for Optical Engineering, vol. 4684 I, Jan. 2002, pp. 363–70. Scopus, doi:10.1117/12.467177.
Markey MK, Lo JY, Tourassi GD, Floyd CE. Cluster analysis of BI-RADS™ descriptions of biopsy-proven breast lesions. Proceedings of SPIE - The International Society for Optical Engineering. 2002 Jan 1;4684 I:363–370.

Published In

Proceedings of SPIE - The International Society for Optical Engineering

DOI

ISSN

0277-786X

Publication Date

January 1, 2002

Volume

4684 I

Start / End Page

363 / 370

Related Subject Headings

  • 5102 Atomic, molecular and optical physics
  • 4009 Electronics, sensors and digital hardware
  • 4006 Communications engineering