Skip to main content
Journal cover image

Differences between computer-aided diagnosis of breast masses and that of calcifications.

Publication ,  Journal Article
Markey, MK; Lo, JY; Floyd, CE
Published in: Radiology
May 2002

PURPOSE: To compare the performance of a computer-aided diagnosis (CAD) system for diagnosis of previously detected lesions, based on radiologist-extracted findings on masses and calcifications. MATERIALS AND METHODS: A feed-forward, back-propagation artificial neural network (BP-ANN) was trained in a round-robin (leave-one-out) manner to predict biopsy outcome from mammographic findings (according to the Breast Imaging Reporting and Data System) and patient age. The BP-ANN was trained by using a large (>1,000 cases) heterogeneous data set containing masses and microcalcifications. The performances of the BP-ANN on masses and microcalcifications were compared with use of receiver operating characteristic analysis and a z test for uncorrelated samples. RESULTS: The BP-ANN performed significantly better on masses than microcalcifications in terms of both the area under the receiver operating characteristic curve and the partial receiver operating characteristic area index. A similar difference in performance was observed with a second model (linear discriminant analysis) and also with a second data set from a similar institution. CONCLUSION: Masses and calcifications should be considered separately when evaluating CAD systems for breast cancer diagnosis.

Duke Scholars

Published In

Radiology

DOI

ISSN

0033-8419

Publication Date

May 2002

Volume

223

Issue

2

Start / End Page

489 / 493

Location

United States

Related Subject Headings

  • Sensitivity and Specificity
  • ROC Curve
  • Nuclear Medicine & Medical Imaging
  • Neural Networks, Computer
  • Middle Aged
  • Mammography
  • Humans
  • Female
  • Discriminant Analysis
  • Diagnosis, Differential
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Markey, M. K., Lo, J. Y., & Floyd, C. E. (2002). Differences between computer-aided diagnosis of breast masses and that of calcifications. Radiology, 223(2), 489–493. https://doi.org/10.1148/radiol.2232011257
Markey, Mia K., Joseph Y. Lo, and Carey E. Floyd. “Differences between computer-aided diagnosis of breast masses and that of calcifications.Radiology 223, no. 2 (May 2002): 489–93. https://doi.org/10.1148/radiol.2232011257.
Markey MK, Lo JY, Floyd CE. Differences between computer-aided diagnosis of breast masses and that of calcifications. Radiology. 2002 May;223(2):489–93.
Markey, Mia K., et al. “Differences between computer-aided diagnosis of breast masses and that of calcifications.Radiology, vol. 223, no. 2, May 2002, pp. 489–93. Pubmed, doi:10.1148/radiol.2232011257.
Markey MK, Lo JY, Floyd CE. Differences between computer-aided diagnosis of breast masses and that of calcifications. Radiology. 2002 May;223(2):489–493.
Journal cover image

Published In

Radiology

DOI

ISSN

0033-8419

Publication Date

May 2002

Volume

223

Issue

2

Start / End Page

489 / 493

Location

United States

Related Subject Headings

  • Sensitivity and Specificity
  • ROC Curve
  • Nuclear Medicine & Medical Imaging
  • Neural Networks, Computer
  • Middle Aged
  • Mammography
  • Humans
  • Female
  • Discriminant Analysis
  • Diagnosis, Differential