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One-dimensional model of cardiac defibrillation.

Publication ,  Journal Article
Plonsey, R; Barr, RC; Witkowski, FX
Published in: Medical & biological engineering & computing
September 1991

The response of a single strand of cardiac cells to a uniform defibrillatory shock assuming steady-state linear conditions is examined. It is argued that the effect of this current is quantitatively described by the induced transmembrane potential even under passive conditions. The characteristics of the single strand are those that would exist if the heart was a system of equivalent parallel pathways from apex to base. It is shown that essentially every cell is both hyperpolarized and depolarised from the shock by an amount proportional to the stimulus intensity and the intercellular junctional resistance. For physiological values of model parameters the evaluated depolarisations are consistent with levels necessary to affect electrophysiological behaviour.

Duke Scholars

Published In

Medical & biological engineering & computing

DOI

EISSN

1741-0444

ISSN

0140-0118

Publication Date

September 1991

Volume

29

Issue

5

Start / End Page

465 / 469

Related Subject Headings

  • Models, Cardiovascular
  • Membrane Potentials
  • Humans
  • Heart
  • Electric Countershock
  • Biomedical Engineering
  • 4611 Machine learning
  • 4603 Computer vision and multimedia computation
  • 4003 Biomedical engineering
  • 0906 Electrical and Electronic Engineering
 

Citation

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ICMJE
MLA
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Plonsey, R., Barr, R. C., & Witkowski, F. X. (1991). One-dimensional model of cardiac defibrillation. Medical & Biological Engineering & Computing, 29(5), 465–469. https://doi.org/10.1007/bf02442315
Plonsey, R., R. C. Barr, and F. X. Witkowski. “One-dimensional model of cardiac defibrillation.Medical & Biological Engineering & Computing 29, no. 5 (September 1991): 465–69. https://doi.org/10.1007/bf02442315.
Plonsey R, Barr RC, Witkowski FX. One-dimensional model of cardiac defibrillation. Medical & biological engineering & computing. 1991 Sep;29(5):465–9.
Plonsey, R., et al. “One-dimensional model of cardiac defibrillation.Medical & Biological Engineering & Computing, vol. 29, no. 5, Sept. 1991, pp. 465–69. Epmc, doi:10.1007/bf02442315.
Plonsey R, Barr RC, Witkowski FX. One-dimensional model of cardiac defibrillation. Medical & biological engineering & computing. 1991 Sep;29(5):465–469.
Journal cover image

Published In

Medical & biological engineering & computing

DOI

EISSN

1741-0444

ISSN

0140-0118

Publication Date

September 1991

Volume

29

Issue

5

Start / End Page

465 / 469

Related Subject Headings

  • Models, Cardiovascular
  • Membrane Potentials
  • Humans
  • Heart
  • Electric Countershock
  • Biomedical Engineering
  • 4611 Machine learning
  • 4603 Computer vision and multimedia computation
  • 4003 Biomedical engineering
  • 0906 Electrical and Electronic Engineering