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Fast modelling of the collimator-detector response in Monte Carlo simulation of SPECT imaging using the angular response function.

Publication ,  Journal Article
Song, X; Segars, WP; Du, Y; Tsui, BMW; Frey, EC
Published in: Phys Med Biol
April 21, 2005

Interactions of incident photons with the collimator and detector, including septal penetration, scatter and x-ray fluorescence, are significant sources of image degradation in applications of SPECT including dual isotope imaging and imaging using radioisotopes that emit high- or medium-energy photons. Modelling these interactions using full Monte Carlo (MC) simulations is computationally very demanding. We present a new method based on the use of angular response functions (ARFs). The ARF is a function of the incident photon's direction and energy and represents the probability that a photon will either interact with or pass through the collimator, and be detected at the intersection of the photon's direction vector and the detection plane in an energy window of interest. The ARFs were pre-computed using full MC simulations of point sources that include propagation through the collimator-detector system. We have implemented the ARF method for use in conjunction with the SimSET/PHG MC code to provide fast modelling of both interactions in the patient and in the collimator-detector system. Validation results in the three cases studied show that there was good agreement between the projections generated using the ARF method and those from previously validated full MC simulations, but with hundred to thousand fold reductions in simulation time.

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Published In

Phys Med Biol

DOI

ISSN

0031-9155

Publication Date

April 21, 2005

Volume

50

Issue

8

Start / End Page

1791 / 1804

Location

England

Related Subject Headings

  • Transducers
  • Tomography, Emission-Computed, Single-Photon
  • Sensitivity and Specificity
  • Reproducibility of Results
  • Phantoms, Imaging
  • Nuclear Medicine & Medical Imaging
  • Monte Carlo Method
  • Models, Statistical
  • Models, Biological
  • Image Interpretation, Computer-Assisted
 

Citation

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Song, X., Segars, W. P., Du, Y., Tsui, B. M. W., & Frey, E. C. (2005). Fast modelling of the collimator-detector response in Monte Carlo simulation of SPECT imaging using the angular response function. Phys Med Biol, 50(8), 1791–1804. https://doi.org/10.1088/0031-9155/50/8/011
Song, X., W. P. Segars, Y. Du, B. M. W. Tsui, and E. C. Frey. “Fast modelling of the collimator-detector response in Monte Carlo simulation of SPECT imaging using the angular response function.Phys Med Biol 50, no. 8 (April 21, 2005): 1791–1804. https://doi.org/10.1088/0031-9155/50/8/011.
Song X, Segars WP, Du Y, Tsui BMW, Frey EC. Fast modelling of the collimator-detector response in Monte Carlo simulation of SPECT imaging using the angular response function. Phys Med Biol. 2005 Apr 21;50(8):1791–804.
Song, X., et al. “Fast modelling of the collimator-detector response in Monte Carlo simulation of SPECT imaging using the angular response function.Phys Med Biol, vol. 50, no. 8, Apr. 2005, pp. 1791–804. Pubmed, doi:10.1088/0031-9155/50/8/011.
Song X, Segars WP, Du Y, Tsui BMW, Frey EC. Fast modelling of the collimator-detector response in Monte Carlo simulation of SPECT imaging using the angular response function. Phys Med Biol. 2005 Apr 21;50(8):1791–1804.
Journal cover image

Published In

Phys Med Biol

DOI

ISSN

0031-9155

Publication Date

April 21, 2005

Volume

50

Issue

8

Start / End Page

1791 / 1804

Location

England

Related Subject Headings

  • Transducers
  • Tomography, Emission-Computed, Single-Photon
  • Sensitivity and Specificity
  • Reproducibility of Results
  • Phantoms, Imaging
  • Nuclear Medicine & Medical Imaging
  • Monte Carlo Method
  • Models, Statistical
  • Models, Biological
  • Image Interpretation, Computer-Assisted