A physical map of the human genome.
Publication
, Journal Article
McPherson, JD; Marra, M; Hillier, L; Waterston, RH; Chinwalla, A; Wallis, J; Sekhon, M; Wylie, K; Mardis, ER; Wilson, RK; Fulton, R; French, L ...
Published in: Nature
February 15, 2001
The human genome is by far the largest genome to be sequenced, and its size and complexity present many challenges for sequence assembly. The International Human Genome Sequencing Consortium constructed a map of the whole genome to enable the selection of clones for sequencing and for the accurate assembly of the genome sequence. Here we report the construction of the whole-genome bacterial artificial chromosome (BAC) map and its integration with previous landmark maps and information from mapping efforts focused on specific chromosomal regions. We also describe the integration of sequence data with the map.
Duke Scholars
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Published In
Nature
DOI
ISSN
0028-0836
Publication Date
February 15, 2001
Volume
409
Issue
6822
Start / End Page
934 / 941
Location
England
Related Subject Headings
- Repetitive Sequences, Nucleic Acid
- In Situ Hybridization, Fluorescence
- Humans
- Genome, Human
- General Science & Technology
- Gene Duplication
- DNA Fingerprinting
- Contig Mapping
- Cloning, Molecular
- Chromosomes, Artificial, Bacterial
Citation
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Chicago
ICMJE
MLA
NLM
McPherson, J. D., Marra, M., Hillier, L., Waterston, R. H., Chinwalla, A., Wallis, J., … International Human Genome Mapping Consortium, . (2001). A physical map of the human genome. Nature, 409(6822), 934–941. https://doi.org/10.1038/35057157
McPherson, J. D., M. Marra, L. Hillier, R. H. Waterston, A. Chinwalla, J. Wallis, M. Sekhon, et al. “A physical map of the human genome.” Nature 409, no. 6822 (February 15, 2001): 934–41. https://doi.org/10.1038/35057157.
McPherson JD, Marra M, Hillier L, Waterston RH, Chinwalla A, Wallis J, et al. A physical map of the human genome. Nature. 2001 Feb 15;409(6822):934–41.
McPherson, J. D., et al. “A physical map of the human genome.” Nature, vol. 409, no. 6822, Feb. 2001, pp. 934–41. Pubmed, doi:10.1038/35057157.
McPherson JD, Marra M, Hillier L, Waterston RH, Chinwalla A, Wallis J, Sekhon M, Wylie K, Mardis ER, Wilson RK, Fulton R, Kucaba TA, Wagner-McPherson C, Barbazuk WB, Gregory SG, Humphray SJ, French L, Evans RS, Bethel G, Whittaker A, Holden JL, McCann OT, Dunham A, Soderlund C, Scott CE, Bentley DR, Schuler G, Chen HC, Jang W, Green ED, Idol JR, Maduro VV, Montgomery KT, Lee E, Miller A, Emerling S, Kucherlapati, Gibbs R, Scherer S, Gorrell JH, Sodergren E, Clerc-Blankenburg K, Tabor P, Naylor S, Garcia D, de Jong PJ, Catanese JJ, Nowak N, Osoegawa K, Qin S, Rowen L, Madan A, Dors M, Hood L, Trask B, Friedman C, Massa H, Cheung VG, Kirsch IR, Reid T, Yonescu R, Weissenbach J, Bruls T, Heilig R, Branscomb E, Olsen A, Doggett N, Cheng JF, Hawkins T, Myers RM, Shang J, Ramirez L, Schmutz J, Velasquez O, Dixon K, Stone NE, Cox DR, Haussler D, Kent WJ, Furey T, Rogic S, Kennedy S, Jones S, Rosenthal A, Wen G, Schilhabel M, Gloeckner G, Nyakatura G, Siebert R, Schlegelberger B, Korenberg J, Chen XN, Fujiyama A, Hattori M, Toyoda A, Yada T, Park HS, Sakaki Y, Shimizu N, Asakawa S, Kawasaki K, Sasaki T, Shintani A, Shimizu A, Shibuya K, Kudoh J, Minoshima S, Ramser J, Seranski P, Hoff C, Poustka A, Reinhardt R, Lehrach H, International Human Genome Mapping Consortium. A physical map of the human genome. Nature. 2001 Feb 15;409(6822):934–941.
Published In
Nature
DOI
ISSN
0028-0836
Publication Date
February 15, 2001
Volume
409
Issue
6822
Start / End Page
934 / 941
Location
England
Related Subject Headings
- Repetitive Sequences, Nucleic Acid
- In Situ Hybridization, Fluorescence
- Humans
- Genome, Human
- General Science & Technology
- Gene Duplication
- DNA Fingerprinting
- Contig Mapping
- Cloning, Molecular
- Chromosomes, Artificial, Bacterial