Stretching single molecules into novel conformations using the atomic force microscope.
Publication
, Journal Article
Fisher, TE; Marszalek, PE; Fernandez, JM
Published in: Nature structural biology
September 2000
A dense network of interconnected proteins and carbohydrates forms the complex mechanical scaffold of living tissues. The recently developed technique of single molecule force spectroscopy using the atomic force microscope (AFM) has enabled a detailed analysis of the force-induced conformations of these molecules and the determinants of their mechanical stability. These studies provide some of the basic knowledge required to understand the mechanical interactions that define all biological organisms.
Duke Scholars
Published In
Nature structural biology
DOI
ISSN
1072-8368
Publication Date
September 2000
Volume
7
Issue
9
Start / End Page
719 / 724
Related Subject Headings
- Stress, Mechanical
- Recombinant Fusion Proteins
- Proteins
- Protein Renaturation
- Protein Folding
- Protein Conformation
- Polysaccharides
- Polyproteins
- Mutagenesis
- Microscopy, Atomic Force
Citation
APA
Chicago
ICMJE
MLA
NLM
Fisher, T. E., Marszalek, P. E., & Fernandez, J. M. (2000). Stretching single molecules into novel conformations using the atomic force microscope. Nature Structural Biology, 7(9), 719–724. https://doi.org/10.1038/78936
Fisher, T. E., P. E. Marszalek, and J. M. Fernandez. “Stretching single molecules into novel conformations using the atomic force microscope.” Nature Structural Biology 7, no. 9 (September 2000): 719–24. https://doi.org/10.1038/78936.
Fisher TE, Marszalek PE, Fernandez JM. Stretching single molecules into novel conformations using the atomic force microscope. Nature structural biology. 2000 Sep;7(9):719–24.
Fisher, T. E., et al. “Stretching single molecules into novel conformations using the atomic force microscope.” Nature Structural Biology, vol. 7, no. 9, Sept. 2000, pp. 719–24. Epmc, doi:10.1038/78936.
Fisher TE, Marszalek PE, Fernandez JM. Stretching single molecules into novel conformations using the atomic force microscope. Nature structural biology. 2000 Sep;7(9):719–724.
Published In
Nature structural biology
DOI
ISSN
1072-8368
Publication Date
September 2000
Volume
7
Issue
9
Start / End Page
719 / 724
Related Subject Headings
- Stress, Mechanical
- Recombinant Fusion Proteins
- Proteins
- Protein Renaturation
- Protein Folding
- Protein Conformation
- Polysaccharides
- Polyproteins
- Mutagenesis
- Microscopy, Atomic Force