Evaluation of information-theoretic similarity measures for content-based retrieval and detection of masses in mammograms.
The purpose of this study was to evaluate image similarity measures employed in an information-theoretic computer-assisted detection (IT-CAD) scheme. The scheme was developed for content-based retrieval and detection of masses in screening mammograms. The study is aimed toward an interactive clinical paradigm where physicians query the proposed IT-CAD scheme on mammographic locations that are either visually suspicious or indicated as suspicious by other cuing CAD systems. The IT-CAD scheme provides an evidence-based, second opinion for query mammographic locations using a knowledge database of mass and normal cases. In this study, eight entropy-based similarity measures were compared with respect to retrieval precision and detection accuracy using a database of 1820 mammographic regions of interest. The IT-CAD scheme was then validated on a separate database for false positive reduction of progressively more challenging visual cues generated by an existing, in-house mass detection system. The study showed that the image similarity measures fall into one of two categories; one category is better suited to the retrieval of semantically similar cases while the second is more effective with knowledge-based decisions regarding the presence of a true mass in the query location. In addition, the IT-CAD scheme yielded a substantial reduction in false-positive detections while maintaining high detection rate for malignant masses.
Duke Scholars
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Related Subject Headings
- Subtraction Technique
- Sensitivity and Specificity
- Reproducibility of Results
- Radiographic Image Interpretation, Computer-Assisted
- Radiographic Image Enhancement
- Pattern Recognition, Automated
- Nuclear Medicine & Medical Imaging
- Mammography
- Information Theory
- Information Storage and Retrieval
Citation
Published In
DOI
ISSN
Publication Date
Volume
Issue
Start / End Page
Location
Related Subject Headings
- Subtraction Technique
- Sensitivity and Specificity
- Reproducibility of Results
- Radiographic Image Interpretation, Computer-Assisted
- Radiographic Image Enhancement
- Pattern Recognition, Automated
- Nuclear Medicine & Medical Imaging
- Mammography
- Information Theory
- Information Storage and Retrieval