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Dedicated breast computed tomography: volume image denoising via a partial-diffusion equation based technique.

Publication ,  Journal Article
Xia, JQ; Lo, JY; Yang, K; Floyd, CE; Boone, JM
Published in: Med Phys
May 2008

Dedicated breast computed tomography (CT) imaging possesses the potential for improved lesion detection over conventional mammograms, especially for women with dense breasts. The breast CT images are acquired with a glandular dose comparable to that of standard two-view mammography for a single breast. Due to dose constraints, the reconstructed volume has a non-negligible quantum noise when thin section CT slices are visualized. It is thus desirable to reduce noise in the reconstructed breast volume without loss of spatial resolution. In this study, partial diffusion equation (PDE) based denoising techniques specifically for breast CT were applied at different steps along the reconstruction process and it was found that denoising performed better when applied to the projection data rather than reconstructed data. Simulation results from the contrast detail phantom show that the PDE technique outperforms Wiener denoising as well as adaptive trimmed mean filter. The PDE technique increases its performance advantage relative to Wiener techniques when the photon fluence is reduced. With the PDE technique, the sensitivity for lesion detection using the contrast detail phantom drops by less than 7% when the dose is cut down to 40% of the two-view mammography. For subjective evaluation, the PDE technique was applied to two human subject breast data sets acquired on a prototype breast CT system. The denoised images had appealing visual characteristics with much lower noise levels and improved tissue textures while maintaining sharpness of the original reconstructed volume.

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Published In

Med Phys

DOI

ISSN

0094-2405

Publication Date

May 2008

Volume

35

Issue

5

Start / End Page

1950 / 1958

Location

United States

Related Subject Headings

  • X-Rays
  • Tomography, X-Ray Computed
  • Sensitivity and Specificity
  • Radiographic Image Interpretation, Computer-Assisted
  • Quantum Theory
  • Nuclear Medicine & Medical Imaging
  • Models, Theoretical
  • Models, Statistical
  • Mammography
  • Image Processing, Computer-Assisted
 

Citation

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Xia, J. Q., Lo, J. Y., Yang, K., Floyd, C. E., & Boone, J. M. (2008). Dedicated breast computed tomography: volume image denoising via a partial-diffusion equation based technique. Med Phys, 35(5), 1950–1958. https://doi.org/10.1118/1.2903436
Xia, Jessie Q., Joseph Y. Lo, Kai Yang, Carey E. Floyd, and John M. Boone. “Dedicated breast computed tomography: volume image denoising via a partial-diffusion equation based technique.Med Phys 35, no. 5 (May 2008): 1950–58. https://doi.org/10.1118/1.2903436.
Xia JQ, Lo JY, Yang K, Floyd CE, Boone JM. Dedicated breast computed tomography: volume image denoising via a partial-diffusion equation based technique. Med Phys. 2008 May;35(5):1950–8.
Xia, Jessie Q., et al. “Dedicated breast computed tomography: volume image denoising via a partial-diffusion equation based technique.Med Phys, vol. 35, no. 5, May 2008, pp. 1950–58. Pubmed, doi:10.1118/1.2903436.
Xia JQ, Lo JY, Yang K, Floyd CE, Boone JM. Dedicated breast computed tomography: volume image denoising via a partial-diffusion equation based technique. Med Phys. 2008 May;35(5):1950–1958.

Published In

Med Phys

DOI

ISSN

0094-2405

Publication Date

May 2008

Volume

35

Issue

5

Start / End Page

1950 / 1958

Location

United States

Related Subject Headings

  • X-Rays
  • Tomography, X-Ray Computed
  • Sensitivity and Specificity
  • Radiographic Image Interpretation, Computer-Assisted
  • Quantum Theory
  • Nuclear Medicine & Medical Imaging
  • Models, Theoretical
  • Models, Statistical
  • Mammography
  • Image Processing, Computer-Assisted