Poliovirus and its cellular receptor: a molecular genetic dissection of a virus/receptor affinity interaction.
Publication
, Journal Article
Solecki, D; Gromeier, M; Harber, J; Bernhardt, G; Wimmer, E
Published in: J Mol Recognit
1998
The ability of a virus to attach to a susceptible host cell is of utmost importance for the initiation of viral life cycle. Cell surface proteins called viral receptors mediate the initial steps of virus attachment and uptake. Poliovirus (PV) is one of the most studied animal viruses and its interaction with its cellular receptor, the human poliovirus receptor (hPVR) has been well characterized. This review will present our current understanding of the PV/hPVR interaction at the genetic and biochemical level. In addition, we will also discuss the implications of the PV/hPVR interaction on PV tissue tropism and the evolution of the three PV serotypes.
Duke Scholars
Published In
J Mol Recognit
DOI
ISSN
0952-3499
Publication Date
1998
Volume
11
Issue
1-6
Start / End Page
2 / 9
Location
England
Related Subject Headings
- Receptors, Virus
- Protein Conformation
- Poliovirus
- Poliomyelitis
- Organ Specificity
- Molecular Biology
- Models, Molecular
- Humans
- Genes, Viral
- Evolution, Molecular
Citation
APA
Chicago
ICMJE
MLA
NLM
Solecki, D., Gromeier, M., Harber, J., Bernhardt, G., & Wimmer, E. (1998). Poliovirus and its cellular receptor: a molecular genetic dissection of a virus/receptor affinity interaction. J Mol Recognit, 11(1–6), 2–9. https://doi.org/10.1002/(SICI)1099-1352(199812)11:1/6<2::AID-JMR380>3.0.CO;2-D
Solecki, D., M. Gromeier, J. Harber, G. Bernhardt, and E. Wimmer. “Poliovirus and its cellular receptor: a molecular genetic dissection of a virus/receptor affinity interaction.” J Mol Recognit 11, no. 1–6 (1998): 2–9. https://doi.org/10.1002/(SICI)1099-1352(199812)11:1/6<2::AID-JMR380>3.0.CO;2-D.
Solecki D, Gromeier M, Harber J, Bernhardt G, Wimmer E. Poliovirus and its cellular receptor: a molecular genetic dissection of a virus/receptor affinity interaction. J Mol Recognit. 1998;11(1–6):2–9.
Solecki, D., et al. “Poliovirus and its cellular receptor: a molecular genetic dissection of a virus/receptor affinity interaction.” J Mol Recognit, vol. 11, no. 1–6, 1998, pp. 2–9. Pubmed, doi:10.1002/(SICI)1099-1352(199812)11:1/6<2::AID-JMR380>3.0.CO;2-D.
Solecki D, Gromeier M, Harber J, Bernhardt G, Wimmer E. Poliovirus and its cellular receptor: a molecular genetic dissection of a virus/receptor affinity interaction. J Mol Recognit. 1998;11(1–6):2–9.
Published In
J Mol Recognit
DOI
ISSN
0952-3499
Publication Date
1998
Volume
11
Issue
1-6
Start / End Page
2 / 9
Location
England
Related Subject Headings
- Receptors, Virus
- Protein Conformation
- Poliovirus
- Poliomyelitis
- Organ Specificity
- Molecular Biology
- Models, Molecular
- Humans
- Genes, Viral
- Evolution, Molecular