Overview
I am a classically trained virologist with a focus on molecular mechanisms of RNA virus pathogenesis. My career is dedicated to unraveling RNA virus:host relations and devising methods of exploiting them for cancer immunotherapy and vaccine design. My background is in translation regulation and mRNA metabolism, viral RNA sensing and innate immunity, and cancer immunology and immunotherapy. Basic mechanistic research in my laboratory is supporting an ambitious clinical translational research program with active multi-center clinical trials in several cancer indications.
Current Appointments & Affiliations
Cless Family Distinguished Professor in Neuro-Oncology
·
2023 - Present
Neurosurgery, Neuro-Oncology,
Neurosurgery
Professor of Neurosurgery
·
2016 - Present
Neurosurgery, Neuro-Oncology,
Neurosurgery
Professor in Medicine
·
2016 - Present
Medicine, Infectious Diseases,
Medicine
Professor in Molecular Genetics and Microbiology
·
2016 - Present
Molecular Genetics and Microbiology,
Basic Science Departments
Professor of Cell Biology
·
2022 - Present
Cell Biology,
Basic Science Departments
Member of the Duke Cancer Institute
·
1999 - Present
Duke Cancer Institute,
Institutes and Centers
Education, Training & Certifications
University of Hamburg (Germany) ·
1992
M.D.