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Relaxation of hyperpolarized 129Xe in a deflating polymer bag.

Publication ,  Journal Article
Möller, HE; Cleveland, ZI; Driehuys, B
Published in: J Magn Reson
September 2011

In magnetic resonance imaging with hyperpolarized (HP) noble gases, data is often acquired during prolonged gas delivery from a storage reservoir. However, little is known about the extent to which relaxation within the reservoir will limit the useful acquisition time. For quantitative characterization, 129Xe relaxation was studied in a bag made of polyvinyl fluoride (Tedlar). Particular emphasis was on wall relaxation, as this mechanism is expected to dominate. The HP 129Xe magnetization dynamics in the deflating bag were accurately described by a model assuming dissolution of Xe in the polymer matrix and dipolar relaxation with neighboring nuclear spins. In particular, the wall relaxation rate changed linearly with the surface-to-volume ratio and exhibited a relaxivity of κ=0.392±0.008 cm/h, which is in reasonable agreement with κ=0.331±0.051 cm/h measured in a static Tedlar bag. Estimates for the bulk gas-phase 129Xe relaxation yielded T1bulk=2.55±0.22 h, which is dominated by intrinsic Xe-Xe relaxation, with small additional contributions from magnetic field inhomogeneities and oxygen-induced relaxation. Calculations based on these findings indicate that relaxation may limit HP 129Xe experiments when slow gas delivery rates are employed as, for example, in mouse imaging or vascular infusion experiments.

Duke Scholars

Published In

J Magn Reson

DOI

EISSN

1096-0856

Publication Date

September 2011

Volume

212

Issue

1

Start / End Page

109 / 115

Location

United States

Related Subject Headings

  • Xenon Isotopes
  • Xenon
  • Respiratory Mechanics
  • Radio Waves
  • Polyvinyls
  • Polymers
  • Mice
  • Magnetic Resonance Imaging
  • Image Processing, Computer-Assisted
  • Electromagnetic Fields
 

Citation

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MLA
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Möller, H. E., Cleveland, Z. I., & Driehuys, B. (2011). Relaxation of hyperpolarized 129Xe in a deflating polymer bag. J Magn Reson, 212(1), 109–115. https://doi.org/10.1016/j.jmr.2011.06.017
Möller, Harald E., Zackary I. Cleveland, and Bastiaan Driehuys. “Relaxation of hyperpolarized 129Xe in a deflating polymer bag.J Magn Reson 212, no. 1 (September 2011): 109–15. https://doi.org/10.1016/j.jmr.2011.06.017.
Möller HE, Cleveland ZI, Driehuys B. Relaxation of hyperpolarized 129Xe in a deflating polymer bag. J Magn Reson. 2011 Sep;212(1):109–15.
Möller, Harald E., et al. “Relaxation of hyperpolarized 129Xe in a deflating polymer bag.J Magn Reson, vol. 212, no. 1, Sept. 2011, pp. 109–15. Pubmed, doi:10.1016/j.jmr.2011.06.017.
Möller HE, Cleveland ZI, Driehuys B. Relaxation of hyperpolarized 129Xe in a deflating polymer bag. J Magn Reson. 2011 Sep;212(1):109–115.
Journal cover image

Published In

J Magn Reson

DOI

EISSN

1096-0856

Publication Date

September 2011

Volume

212

Issue

1

Start / End Page

109 / 115

Location

United States

Related Subject Headings

  • Xenon Isotopes
  • Xenon
  • Respiratory Mechanics
  • Radio Waves
  • Polyvinyls
  • Polymers
  • Mice
  • Magnetic Resonance Imaging
  • Image Processing, Computer-Assisted
  • Electromagnetic Fields