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A transcranial magnetic stimulator inducing near-rectangular pulses with controllable pulse width (cTMS).

Publication ,  Journal Article
Peterchev, AV; Jalinous, R; Lisanby, SH
Published in: IEEE Trans Biomed Eng
January 2008

A novel transcranial magnetic stimulation (TMS) device with controllable pulse width (PW) and near-rectangular pulse shape (cTMS) is described. The cTMS device uses an insulated gate bipolar transistor (IGBT) with appropriate snubbers to switch coil currents up to 6 kA, enabling PW control from 5 micros to over 100 micros. The near-rectangular induced electric field pulses use 2%-34% less energy and generate 67%-72% less coil heating compared to matched conventional cosine pulses. CTMS is used to stimulate rhesus monkey motor cortex in vivo with PWs of 20 to 100 micros, demonstrating the expected decrease of threshold pulse amplitude with increasing PW. The technological solutions used in the cTMS prototype can expand functionality, and reduce power consumption and coil heating in TMS, enhancing its research and therapeutic applications.

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Published In

IEEE Trans Biomed Eng

DOI

ISSN

0018-9294

Publication Date

January 2008

Volume

55

Issue

1

Start / End Page

257 / 266

Location

United States

Related Subject Headings

  • Transducers
  • Transcranial Magnetic Stimulation
  • Signal Processing, Computer-Assisted
  • Equipment Failure Analysis
  • Equipment Design
  • Biomedical Engineering
  • 4603 Computer vision and multimedia computation
  • 4009 Electronics, sensors and digital hardware
  • 4003 Biomedical engineering
  • 0906 Electrical and Electronic Engineering
 

Citation

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Peterchev, A. V., Jalinous, R., & Lisanby, S. H. (2008). A transcranial magnetic stimulator inducing near-rectangular pulses with controllable pulse width (cTMS). IEEE Trans Biomed Eng, 55(1), 257–266. https://doi.org/10.1109/TBME.2007.900540
Peterchev, Angel V., Reza Jalinous, and Sarah H. Lisanby. “A transcranial magnetic stimulator inducing near-rectangular pulses with controllable pulse width (cTMS).IEEE Trans Biomed Eng 55, no. 1 (January 2008): 257–66. https://doi.org/10.1109/TBME.2007.900540.
Peterchev AV, Jalinous R, Lisanby SH. A transcranial magnetic stimulator inducing near-rectangular pulses with controllable pulse width (cTMS). IEEE Trans Biomed Eng. 2008 Jan;55(1):257–66.
Peterchev, Angel V., et al. “A transcranial magnetic stimulator inducing near-rectangular pulses with controllable pulse width (cTMS).IEEE Trans Biomed Eng, vol. 55, no. 1, Jan. 2008, pp. 257–66. Pubmed, doi:10.1109/TBME.2007.900540.
Peterchev AV, Jalinous R, Lisanby SH. A transcranial magnetic stimulator inducing near-rectangular pulses with controllable pulse width (cTMS). IEEE Trans Biomed Eng. 2008 Jan;55(1):257–266.

Published In

IEEE Trans Biomed Eng

DOI

ISSN

0018-9294

Publication Date

January 2008

Volume

55

Issue

1

Start / End Page

257 / 266

Location

United States

Related Subject Headings

  • Transducers
  • Transcranial Magnetic Stimulation
  • Signal Processing, Computer-Assisted
  • Equipment Failure Analysis
  • Equipment Design
  • Biomedical Engineering
  • 4603 Computer vision and multimedia computation
  • 4009 Electronics, sensors and digital hardware
  • 4003 Biomedical engineering
  • 0906 Electrical and Electronic Engineering