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Accuracy of inhomogeneity correction in photon radiotherapy from CT scans with different settings.

Publication ,  Journal Article
Guan, H; Yin, F-F; Kim, JH
Published in: Phys Med Biol
September 7, 2002

We report an investigation on the accuracy of inhomogeneity correction in photon radiotherapy from CT scans with different settings. Specifically, the dosimetric differences from different CT scan parameters (kV, mAs) to phantoms and from different Hounsfield unit versus electron density (HU-ED) curves to patients are investigated. The absolute dose per monitor units (dose/MU) is used to quantify the results. We found that only for high-density bones (cranium, femoral tube, etc) using small field 18 MV beams, the dose/MU is up to 2% higher for CT scans using 80 kV than for 130 kV at a depth just beyond the bone and is up to 1-1.5% higher for CT scans using 80 mAs than for 300 mAs. For low-density bones (such as femoral head) and lung, the difference is 1% or less with different kV or mAs settings. The dose/MU varies with different HU-ED curves by up to 2%. The HU-ED curve from the stochiometric calibration was found to be more accurate based on a real measurement. A simplified 4-point curve provides nearly the same accuracy as the stochiometric calibration and may be used as an alternative for routine clinical application.

Duke Scholars

Published In

Phys Med Biol

DOI

ISSN

0031-9155

Publication Date

September 7, 2002

Volume

47

Issue

17

Start / End Page

N223 / N231

Location

England

Related Subject Headings

  • Tomography, X-Ray Computed
  • Skull
  • Sensitivity and Specificity
  • Reproducibility of Results
  • Radiotherapy, High-Energy
  • Radiotherapy, Conformal
  • Radiotherapy Planning, Computer-Assisted
  • Radiotherapy Dosage
  • Radiometry
  • Quality Control
 

Citation

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Guan, H., Yin, F.-F., & Kim, J. H. (2002). Accuracy of inhomogeneity correction in photon radiotherapy from CT scans with different settings. Phys Med Biol, 47(17), N223–N231. https://doi.org/10.1088/0031-9155/47/17/402
Guan, Huaiqun, Fang-Fang Yin, and Jae Ho Kim. “Accuracy of inhomogeneity correction in photon radiotherapy from CT scans with different settings.Phys Med Biol 47, no. 17 (September 7, 2002): N223–31. https://doi.org/10.1088/0031-9155/47/17/402.
Guan H, Yin F-F, Kim JH. Accuracy of inhomogeneity correction in photon radiotherapy from CT scans with different settings. Phys Med Biol. 2002 Sep 7;47(17):N223–31.
Guan, Huaiqun, et al. “Accuracy of inhomogeneity correction in photon radiotherapy from CT scans with different settings.Phys Med Biol, vol. 47, no. 17, Sept. 2002, pp. N223–31. Pubmed, doi:10.1088/0031-9155/47/17/402.
Guan H, Yin F-F, Kim JH. Accuracy of inhomogeneity correction in photon radiotherapy from CT scans with different settings. Phys Med Biol. 2002 Sep 7;47(17):N223–N231.
Journal cover image

Published In

Phys Med Biol

DOI

ISSN

0031-9155

Publication Date

September 7, 2002

Volume

47

Issue

17

Start / End Page

N223 / N231

Location

England

Related Subject Headings

  • Tomography, X-Ray Computed
  • Skull
  • Sensitivity and Specificity
  • Reproducibility of Results
  • Radiotherapy, High-Energy
  • Radiotherapy, Conformal
  • Radiotherapy Planning, Computer-Assisted
  • Radiotherapy Dosage
  • Radiometry
  • Quality Control