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The correlation evaluation of a tumor tracking system using multiple external markers.

Publication ,  Journal Article
Yan, H; Yin, F-F; Zhu, G-P; Ajlouni, M; Kim, JH
Published in: Med Phys
November 2006

The purpose of this study is to evaluate the correlations between external markers and internal targets for radiation therapy of lung cancer patients. Using an infrared camera system coupled with a clinical simulator, the simultaneous motions of multiple external markers and an internal target were obtained. The correlation between external and internal signals was analyzed using a cross-covariance function. A linear regression model was employed to generate a composite signal from multiple external markers in order to predict the internal target motion. The external and internal signals, and their correlations, demonstrated a wide range of variation with respect to marker location, motion dimension, and breathing pattern. The performance of the composite signal indicates that when more external signals were taken into account, the mean correlation between the composite signal and internal signal was improved. This implies that a combination of multiple external signals might be an improved way to predict internal target motion. Also, since the characteristics of respiratory signals can vary significantly, certain methods of preprocessing and external signal combination are necessary.

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Published In

Med Phys

DOI

ISSN

0094-2405

Publication Date

November 2006

Volume

33

Issue

11

Start / End Page

4073 / 4084

Location

United States

Related Subject Headings

  • Sensitivity and Specificity
  • Respiratory Mechanics
  • Reproducibility of Results
  • Radiotherapy, Conformal
  • Radiotherapy, Computer-Assisted
  • Photography
  • Nuclear Medicine & Medical Imaging
  • Lung Neoplasms
  • Image Interpretation, Computer-Assisted
  • Humans
 

Citation

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Yan, H., Yin, F.-F., Zhu, G.-P., Ajlouni, M., & Kim, J. H. (2006). The correlation evaluation of a tumor tracking system using multiple external markers. Med Phys, 33(11), 4073–4084. https://doi.org/10.1118/1.2358830
Yan, Hui, Fang-Fang Yin, Guo-Pei Zhu, Munther Ajlouni, and Jae Ho Kim. “The correlation evaluation of a tumor tracking system using multiple external markers.Med Phys 33, no. 11 (November 2006): 4073–84. https://doi.org/10.1118/1.2358830.
Yan H, Yin F-F, Zhu G-P, Ajlouni M, Kim JH. The correlation evaluation of a tumor tracking system using multiple external markers. Med Phys. 2006 Nov;33(11):4073–84.
Yan, Hui, et al. “The correlation evaluation of a tumor tracking system using multiple external markers.Med Phys, vol. 33, no. 11, Nov. 2006, pp. 4073–84. Pubmed, doi:10.1118/1.2358830.
Yan H, Yin F-F, Zhu G-P, Ajlouni M, Kim JH. The correlation evaluation of a tumor tracking system using multiple external markers. Med Phys. 2006 Nov;33(11):4073–4084.

Published In

Med Phys

DOI

ISSN

0094-2405

Publication Date

November 2006

Volume

33

Issue

11

Start / End Page

4073 / 4084

Location

United States

Related Subject Headings

  • Sensitivity and Specificity
  • Respiratory Mechanics
  • Reproducibility of Results
  • Radiotherapy, Conformal
  • Radiotherapy, Computer-Assisted
  • Photography
  • Nuclear Medicine & Medical Imaging
  • Lung Neoplasms
  • Image Interpretation, Computer-Assisted
  • Humans